LOCUS       DAVLTG010000001        82786 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLTG010000001 DAVLTG010000000
VERSION     DAVLTG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.001"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            158..1639
                     /locus_tag="VYN12_000001"
     CDS             158..1639
                     /locus_tag="VYN12_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1414465.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRITSQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2000..3001
                     /locus_tag="VYN12_000002"
     CDS             2000..3001
                     /locus_tag="VYN12_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1414466.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3151..4068
                     /locus_tag="VYN12_000003"
     CDS             3151..4068
                     /locus_tag="VYN12_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1414467.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4079..4969
                     /locus_tag="VYN12_000004"
     CDS             4079..4969
                     /locus_tag="VYN12_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1414468.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4998..6614
                     /locus_tag="VYN12_000005"
     CDS             4998..6614
                     /locus_tag="VYN12_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1414469.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6624..7943
                     /locus_tag="VYN12_000006"
     CDS             6624..7943
                     /locus_tag="VYN12_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1414470.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8154..8226)
                     /locus_tag="VYN12_000007"
     tRNA            complement(8154..8226)
                     /locus_tag="VYN12_000007"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8191..8193),aa:Lys,seq:ctt)
     gene            complement(8491..9762)
                     /locus_tag="VYN12_000008"
     CDS             complement(8491..9762)
                     /locus_tag="VYN12_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1414471.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            10060..10275
                     /locus_tag="VYN12_000009"
     CDS             10060..10275
                     /locus_tag="VYN12_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414472.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10265..10513
                     /locus_tag="VYN12_000010"
     CDS             10265..10513
                     /locus_tag="VYN12_000010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414473.1"
                     /translation="MKNRIIDVFEVVNRLLVITVENPDFEDLRVNQFVKIGDKKYRVR
                     SVPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH"
     gene            10650..10829
                     /locus_tag="VYN12_000011"
     CDS             10650..10829
                     /locus_tag="VYN12_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1414474.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10866..11318
                     /locus_tag="VYN12_000012"
     CDS             10866..11318
                     /locus_tag="VYN12_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1414475.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11609..12079
                     /locus_tag="VYN12_000013"
     CDS             11609..12079
                     /locus_tag="VYN12_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1414476.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12098..13186
                     /locus_tag="VYN12_000014"
     CDS             12098..13186
                     /locus_tag="VYN12_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1414477.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLMLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYCENLLAELEKEMLEGTEDGTRNF"
     gene            13167..13595
                     /locus_tag="VYN12_000015"
     CDS             13167..13595
                     /locus_tag="VYN12_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1414478.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYKLMPIEEFLNSKQAVPQLQGRLRDYLEESL"
     gene            13592..14065
                     /locus_tag="VYN12_000016"
     CDS             13592..14065
                     /locus_tag="VYN12_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414479.1"
                     /translation="MITLVRAGAEDLETIIAIQRASFKAVYEKYHDEYDPYLEDCERI
                     KWKLVERPNSYYYFVKEDEENIGFLRVQTNAELTKAWLGTAAILPQYQGKGYGSKGLS
                     LLEKEFPTITQWDLCTVLQDAGMVAFYEKNGYRQIHIEAEKEGMDMVYMKKLIEK"
     gene            14203..15153
                     /locus_tag="VYN12_000017"
     CDS             14203..15153
                     /locus_tag="VYN12_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1414480.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            15155..15898
                     /locus_tag="VYN12_000018"
     CDS             15155..15898
                     /locus_tag="VYN12_000018"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1414481.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVSGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15909..17705
                     /gene="pepF"
                     /locus_tag="VYN12_000019"
     CDS             15909..17705
                     /gene="pepF"
                     /locus_tag="VYN12_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1414482.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(17765..18442)
                     /locus_tag="VYN12_000020"
     CDS             complement(17765..18442)
                     /locus_tag="VYN12_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1414483.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            18689..19459
                     /locus_tag="VYN12_000021"
     CDS             18689..19459
                     /locus_tag="VYN12_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414484.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            19452..20216
                     /locus_tag="VYN12_000022"
     CDS             19452..20216
                     /locus_tag="VYN12_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414485.1"
                     /translation="MFKLSFQSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            20641..21431
                     /locus_tag="VYN12_000023"
                     /pseudo
     CDS             20641..21431
                     /locus_tag="VYN12_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            21537..22205
                     /locus_tag="VYN12_000024"
     CDS             21537..22205
                     /locus_tag="VYN12_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1414486.1"
                     /translation="MKKFVAELIGTFMLVFIGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAFSIGTVSGAHLNPAVSIAMFVNKRLSSKDLVNYILGQVVGAFIASGAVFLLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLIIGLS
                     LMAMILVGLNITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(22230..22397)
                     /locus_tag="VYN12_000025"
     CDS             complement(22230..22397)
                     /locus_tag="VYN12_000025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414487.1"
                     /translation="MFEVVDRTDEVSLKHCFEVADRTDEVSNHTYGKVKLTWFEEIFE
                     EYHTKKPCSSR"
     gene            complement(22459..22992)
                     /gene="queF"
                     /locus_tag="VYN12_000026"
     CDS             complement(22459..22992)
                     /gene="queF"
                     /locus_tag="VYN12_000026"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1414488.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(23297..23611)
                     /gene="trxA"
                     /locus_tag="VYN12_000027"
     CDS             complement(23297..23611)
                     /gene="trxA"
                     /locus_tag="VYN12_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1414489.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(23628..23849)
                     /locus_tag="VYN12_000028"
     CDS             complement(23628..23849)
                     /locus_tag="VYN12_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1414490.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(23948..24328)
                     /locus_tag="VYN12_000029"
     CDS             complement(23948..24328)
                     /locus_tag="VYN12_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1414491.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRICCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(24472..25425)
                     /locus_tag="VYN12_000030"
     CDS             complement(24472..25425)
                     /locus_tag="VYN12_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1414492.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(25493..26701)
                     /gene="sstT"
                     /locus_tag="VYN12_000031"
                     /pseudo
     CDS             complement(25493..26701)
                     /gene="sstT"
                     /locus_tag="VYN12_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            26840..27400
                     /locus_tag="VYN12_000032"
     CDS             26840..27400
                     /locus_tag="VYN12_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1414493.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            27457..28365
                     /locus_tag="VYN12_000033"
     CDS             27457..28365
                     /locus_tag="VYN12_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1414494.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            28317..28907
                     /locus_tag="VYN12_000034"
     CDS             28317..28907
                     /locus_tag="VYN12_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1414495.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            28910..30016
                     /gene="yqeH"
                     /locus_tag="VYN12_000035"
     CDS             28910..30016
                     /gene="yqeH"
                     /locus_tag="VYN12_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1414496.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            30231..30542
                     /gene="yhbY"
                     /locus_tag="VYN12_000036"
     CDS             30231..30542
                     /gene="yhbY"
                     /locus_tag="VYN12_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1414497.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            30594..31223
                     /locus_tag="VYN12_000037"
     CDS             30594..31223
                     /locus_tag="VYN12_000037"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1414498.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            31223..31816
                     /gene="yqeK"
                     /locus_tag="VYN12_000038"
     CDS             31223..31816
                     /gene="yqeK"
                     /locus_tag="VYN12_000038"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1414499.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            31817..32317
                     /locus_tag="VYN12_000039"
     CDS             31817..32317
                     /locus_tag="VYN12_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1414500.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            32330..32683
                     /gene="rsfS"
                     /locus_tag="VYN12_000040"
     CDS             32330..32683
                     /gene="rsfS"
                     /locus_tag="VYN12_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1414501.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEADSVDISEALA"
     gene            32792..33532
                     /locus_tag="VYN12_000041"
     CDS             32792..33532
                     /locus_tag="VYN12_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1414502.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTDFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSGDMLKIAEKRASSAKQKIDFIEGNMLDLSKSGQYD
                     FVTCYSDSICYMQDEVEVGDVFKEVYNVLNEDGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEVLTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            33542..34639
                     /locus_tag="VYN12_000042"
     CDS             33542..34639
                     /locus_tag="VYN12_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1414503.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIVDLYTERGAEMESFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVDKDVDFASATALRQHQSDQDFLERFMPSVALFEQG
                     SKVSWDDYFPLLRYQILLNPDLTTVYQVNQEMVVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            34877..35131
                     /locus_tag="VYN12_000043"
     CDS             34877..35131
                     /locus_tag="VYN12_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1414504.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            35135..35389
                     /locus_tag="VYN12_000044"
     CDS             35135..35389
                     /locus_tag="VYN12_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV1414505.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            35580..37193
                     /locus_tag="VYN12_000045"
     CDS             35580..37193
                     /locus_tag="VYN12_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1414506.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            37323..37949
                     /gene="gmk"
                     /locus_tag="VYN12_000046"
     CDS             37323..37949
                     /gene="gmk"
                     /locus_tag="VYN12_000046"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1414507.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            37974..38288
                     /locus_tag="VYN12_000047"
     CDS             37974..38288
                     /locus_tag="VYN12_000047"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1414508.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            38354..40750
                     /locus_tag="VYN12_000048"
     CDS             38354..40750
                     /locus_tag="VYN12_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1414509.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            40763..41698
                     /locus_tag="VYN12_000049"
     CDS             40763..41698
                     /locus_tag="VYN12_000049"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1414510.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            41691..43004
                     /gene="rsmB"
                     /locus_tag="VYN12_000050"
     CDS             41691..43004
                     /gene="rsmB"
                     /locus_tag="VYN12_000050"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1414511.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            43019..43759
                     /locus_tag="VYN12_000051"
     CDS             43019..43759
                     /locus_tag="VYN12_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1414512.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAYPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            43756..45735
                     /gene="pknB"
                     /locus_tag="VYN12_000052"
     CDS             43756..45735
                     /gene="pknB"
                     /locus_tag="VYN12_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1414513.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            45850..46608
                     /locus_tag="VYN12_000053"
     CDS             45850..46608
                     /locus_tag="VYN12_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1414514.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            46610..47059
                     /locus_tag="VYN12_000054"
     CDS             46610..47059
                     /locus_tag="VYN12_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1414515.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            47121..47744
                     /locus_tag="VYN12_000055"
                     /pseudo
     CDS             47121..47744
                     /locus_tag="VYN12_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            47812..48060
                     /locus_tag="VYN12_000056"
     CDS             47812..48060
                     /locus_tag="VYN12_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414516.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            48191..49363
                     /locus_tag="VYN12_000057"
     CDS             48191..49363
                     /locus_tag="VYN12_000057"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1414517.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            49363..50637
                     /locus_tag="VYN12_000058"
     CDS             49363..50637
                     /locus_tag="VYN12_000058"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1414518.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(50672..51637)
                     /locus_tag="VYN12_000059"
     CDS             complement(50672..51637)
                     /locus_tag="VYN12_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1414519.1"
                     /translation="MVTKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(51618..53072)
                     /locus_tag="VYN12_000060"
     CDS             complement(51618..53072)
                     /locus_tag="VYN12_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1414520.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGHKTN"
     gene            53449..55332
                     /locus_tag="VYN12_000061"
     CDS             53449..55332
                     /locus_tag="VYN12_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1414521.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     SQGNKVKAGDVLGKFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            55481..56368
                     /locus_tag="VYN12_000062"
     CDS             55481..56368
                     /locus_tag="VYN12_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1414522.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVVRHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(56688..57305)
                     /locus_tag="VYN12_000063"
     CDS             complement(56688..57305)
                     /locus_tag="VYN12_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1414523.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(57720..57933)
                     /locus_tag="VYN12_000064"
                     /pseudo
     CDS             complement(57720..57933)
                     /locus_tag="VYN12_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(58418..58498)
                     /locus_tag="VYN12_000065"
                     /pseudo
     CDS             complement(58418..58498)
                     /locus_tag="VYN12_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            58614..59507
                     /locus_tag="VYN12_000066"
     CDS             58614..59507
                     /locus_tag="VYN12_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414524.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQDQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            59504..60703
                     /locus_tag="VYN12_000067"
     CDS             59504..60703
                     /locus_tag="VYN12_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414525.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(61115..61882)
                     /locus_tag="VYN12_000068"
     CDS             complement(61115..61882)
                     /locus_tag="VYN12_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414526.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(61899..62594)
                     /locus_tag="VYN12_000069"
     CDS             complement(61899..62594)
                     /locus_tag="VYN12_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414527.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(62599..62964)
                     /locus_tag="VYN12_000070"
     CDS             complement(62599..62964)
                     /locus_tag="VYN12_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1414528.1"
                     /translation="MSWTFDNKKTIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            63104..63577
                     /gene="nrdR"
                     /locus_tag="VYN12_000071"
     CDS             63104..63577
                     /gene="nrdR"
                     /locus_tag="VYN12_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1414529.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            63578..64747
                     /locus_tag="VYN12_000072"
     CDS             63578..64747
                     /locus_tag="VYN12_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1414530.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPDLAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQII
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            64748..65644
                     /gene="dnaI"
                     /locus_tag="VYN12_000073"
     CDS             64748..65644
                     /gene="dnaI"
                     /locus_tag="VYN12_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1414531.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            65641..66354
                     /locus_tag="VYN12_000074"
     CDS             65641..66354
                     /locus_tag="VYN12_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1414532.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            66368..67678
                     /gene="der"
                     /locus_tag="VYN12_000075"
     CDS             66368..67678
                     /gene="der"
                     /locus_tag="VYN12_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1414533.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDTIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            67769..68104
                     /locus_tag="VYN12_000076"
     CDS             67769..68104
                     /locus_tag="VYN12_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414534.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            68244..68594
                     /locus_tag="VYN12_000077"
     CDS             68244..68594
                     /locus_tag="VYN12_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414535.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(68826..69677)
                     /locus_tag="VYN12_000078"
     CDS             complement(68826..69677)
                     /locus_tag="VYN12_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1414536.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            70004..70396
                     /locus_tag="VYN12_000079"
     CDS             70004..70396
                     /locus_tag="VYN12_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414537.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            70418..71209
                     /locus_tag="VYN12_000080"
     CDS             70418..71209
                     /locus_tag="VYN12_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414538.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            71202..71843
                     /locus_tag="VYN12_000081"
     CDS             71202..71843
                     /locus_tag="VYN12_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414539.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMILYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            71847..72479
                     /locus_tag="VYN12_000082"
     CDS             71847..72479
                     /locus_tag="VYN12_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1414540.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            72507..72794
                     /locus_tag="VYN12_000083"
     CDS             72507..72794
                     /locus_tag="VYN12_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414541.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            72940..75453
                     /gene="secA"
                     /locus_tag="VYN12_000084"
     CDS             72940..75453
                     /gene="secA"
                     /locus_tag="VYN12_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1414542.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            75534..76565
                     /locus_tag="VYN12_000085"
     CDS             75534..76565
                     /locus_tag="VYN12_000085"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1414543.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            76567..77598
                     /locus_tag="VYN12_000086"
     CDS             76567..77598
                     /locus_tag="VYN12_000086"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1414544.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            77637..78005
                     /locus_tag="VYN12_000087"
     CDS             77637..78005
                     /locus_tag="VYN12_000087"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1414545.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            77995..79098
                     /locus_tag="VYN12_000088"
     CDS             77995..79098
                     /locus_tag="VYN12_000088"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1414546.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFIEASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            79117..81132
                     /gene="recG"
                     /locus_tag="VYN12_000089"
     CDS             79117..81132
                     /gene="recG"
                     /locus_tag="VYN12_000089"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1414547.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRIQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMLALHLEKKEHLD"
     gene            81448..82428
                     /locus_tag="VYN12_000090"
     CDS             81448..82428
                     /locus_tag="VYN12_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1414548.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDHVYNWLCGSEIPFKYLK"
BASE COUNT        24755 a        15351 c        18533 g        24147 t
ORIGIN      
        1 acggtaaaat aagaaaattg tttatatatt gtctccgtag tgttattata cgaaataaaa
       61 gattttagga aaagtcgtta tatcatgcta tacctattct ttgtggtata attgcaagag
      121 gtttaatccg ataatttata aagagagaaa gatattcatg agagatttat tatctaaaaa
      181 aagtcatagg caattagaat tattagaatt attatttgaa cataaacgtt ggtttcatcg
      241 ttctgaacta gcagagttat taaattgtac agaacgtgca gtcaaagatg atctatccca
      301 tgttaaatct gcttttcctg acttgatttt tcattcttct actaatggta tacgcattat
      361 taataccgat gatagtgata ttgaaatggt ttaccatcat ttctttaaac attcaactca
      421 tttttcgatt ttagaattca tcttctttaa tgaaggttgt caagctgaga gtatttgtaa
      481 agaattttat atcagttcat cttcgctcta tcgtattact agccaaatca ataaagtgat
      541 taaaaggcaa tttcaatttg aagtcagtct gacccctgtt caaatcattg gaaatgagag
      601 agacattcgt tacttttttg cacaatattt ttcagaaaaa tattatttcc tagaatggcc
      661 atttgaaaat ttttcatcag agccactatc tcaattgtta gaattggttt ataaggaaac
      721 aagctttcca atgaatttgt caacgcatag aatgctaaag ttgctcctag ttacgaacct
      781 atatagaata aagtttggtc attttatgga agtagataaa gattctttta acgaccaaag
      841 tttggatttt ttaatgcagg cagaaggaat agaaggtgtt gctcagagtt ttgaatcaga
      901 atacaatatc tctttagatg aagaagttgt ttgccaatta tttgtgtctt actttcaaaa
      961 aatgtttttc atagatgaaa gtctctttat gaaatgcgta aaaaaggata gttatgtcga
     1021 aaaatcttac catctattga gtgattttat tgatcagatt tcagtcaagt atcagattga
     1081 aatggagaat aaggataatc tgatttggca tctgcataat accgcacatc tgtatcgtca
     1141 agagttgttt actgagttta ttttatttga tcaaaaaggg aatacaatca ggaactttca
     1201 aaatattttt ccaaaatttg tttcagatat aaaaaaagag ctttctcact atttagagac
     1261 tcttgaggtt tgttctagtt caatgatggt aaatcatcta tcttatacct tcatcactca
     1321 taccaaacat ttggtgatta atttgctaca aaatcagcct aaactaaagg ttttagttat
     1381 gagtaatttt gatcagtatc atgcaaaatt cgttgcagag acactttctt attactgtag
     1441 caataatttt gaactggaag tttggactga attagaatta tcaaaggaat ctttagaaga
     1501 ttcatcttat gatatcatta tttctaattt tattattcct cctattgaaa ataagagact
     1561 catctattca aataatataa acacggtctc actcatatat ttgttaaatg ccatgatgtt
     1621 tattcgatta gatgagtaac caaaaataac aaaaaaacgc tatttcgcgt ttgaactgta
     1681 cctcaaaagt tagacagaaa aaatctaatt tttggggtgt ttttgttaag aaaagacctt
     1741 caatcattta agcaaaatgt acatctagat ttatagccct ctaaaactct tgcttttttg
     1801 tagaagatac gaaaaaagcc ataaaaccaa ggcttttcct gttttatgta gatgtttaca
     1861 catgaaaatt gaagtatttt caaaagctaa ttggagtgat tttattcatg atgggataaa
     1921 tgatctggcc aaaaatgatt gagaaatagt tgcttaaaaa gcatttgcat gatactatat
     1981 attgaaagga ggtgataata tggtagaaca aagaaaatca attaccatga aagatgttgc
     2041 tttagaagca ggagttagtg ttggaactgt ttcacgtgta attaataaag aaaaaggcat
     2101 taaagaagta actttgaaaa aagtggaaca agcgattaaa actttgaatt acattccaga
     2161 ttactacgct agaggaatga aaaaaaatcg aacagaaacg attgcaatca ttgtaccaag
     2221 tatctggcat cccttctttt cagaatttgc tatgcatgtg gaaaatgaag tctataagag
     2281 aaataacaaa ttactcttat gttctatcaa tggtacaaat agagagcaag actatctgga
     2341 gatgttgcgt cataataaag ttgatggagt ggttgccatt acctatagtc caattgaaca
     2401 ttacttgacg tcaggaattc cctttgttag tattgaccgc acatactcag atattgccat
     2461 tccttgtgtt tcatcagata atgatgcagg tggaagagaa gcagctaaac aattaattag
     2521 taaaggatgt cagcatttag cctttgtggg cggacataat acaaccatta atgaaaccaa
     2581 acgtcgtaga atttcatttg aaaagtatgt ccaagagcat aaaatacctc ttagtatttt
     2641 tgatttggat gagacagtta ctgactatta tggaaagcta gagagtttct tggaagaaaa
     2701 ttcttctata gatggaattt ttacaatcaa cgattttaca gctttggatg tgattgaaat
     2761 actagaaaaa aatggcaaac gtattcctca tgatgtccaa attattggat acgatggaat
     2821 taaaatggct ggagatagag attatctact ttcaactatt gaacaaccat tggaagaaat
     2881 ggcaaaagaa gcggttcgta ttttgtttga tataattgat ggaaagactg ttaatttgca
     2941 gacaatccta ccagtaaaat ttgttgaagg aaaaacaaca aaaaatgaaa ataagtcttg
     3001 acagaaagcg ctatcaatga tagaatgaat tcagataaaa agatttattt ttaaaacaaa
     3061 aatgaaacgt ttcaaaaaaa gaaataaaga gacagcgcca agcgctatct tttctagaaa
     3121 aaaatgaaac gtttcaaaaa ggaggttgct atgaatagca aagcgaagca agtttctctt
     3181 tgggaaagaa tcaagaaaca aaaactcttg ttattgatga ctgtccctgg tttagtttta
     3241 acctttatct ttaaatacat ccctatgtat ggggttttaa ttgcatttaa agattacaat
     3301 cctttaaaag gaattttagg gagtgattgg attggttttt ctgagtttac aaaattcata
     3361 tcctctccca actttggtat cttgttagcc aacacattaa aattaagtat ctatggttta
     3421 ttgcttggct ttttaccacc aatcattctt gctattatgc tcaatcaact cttgagtgaa
     3481 aaagtcaaaa aacgaattca gctcatttta tacgcaccaa actttatctc agttgttgtt
     3541 attgtcggta tgattttcct cttcttttca gtgggaggac caatcaacaa ttttctttct
     3601 atgtttggaa tgaaggctga cttcttgaca aatccagact tctttagacc tttatacatc
     3661 tttagtggta tctggcaagg aatgggctgg gcttcaacgc tctacacggc aacattggta
     3721 aatgtagatc cagccttagt agaagcagcc cgactggatg gagccaatat cttccaacga
     3781 atctggcaca ttgatattcc agctcttaag cctattatgg ttatccaatt tgttttagct
     3841 gcaggtggaa ttatgaatgt cggatatgaa aaagcattct tgatgcagac atcgttaaat
     3901 ttgccaactt ctgaaattat ctcgacatat gtctataaag ttggtcttgt atcaggagac
     3961 tattcttact caacagcggt tggtttgttt aatgcagtga ttaacgtagt attgcttgtt
     4021 gcagttaacc aaatcgttaa acgcatgaat aatggtgaag gaatttaagg aggaaagtat
     4081 gaaaaattcg attatggata caaaatttga tagacgtatc ttactcttaa ataaaatcat
     4141 tattgtcttt atcgttttga tgactttgct tcctttactt tatatcgtcg tagcatcctt
     4201 tatggatcct aaggttctgg ttagtagagg gattagcttt aatccagccg attggactgt
     4261 agaaggttac cagcgtgtat tcagtgacca atctattcta agaggtttta tcaattctct
     4321 actatactct tttggatttg cagctttaac agtattgcta tctgtgttta cagcttatcc
     4381 tctttctaag aaagacttgg ttggacgtcg ttggattaac tacttcttga ttgtgactat
     4441 gttctttggt ggtggtttag tcccaactta cttgctcgta aaagaattgg gaatgctcaa
     4501 tactccatgg gctatcattg ttccaggtgc tgtcaacgtt tggaatatta ttcttgctag
     4561 ggcctatttc caaggattgc ctgaagaatt agttgaagct gctgtcattg atggtgcaaa
     4621 tgatttacag attttcttca aaatcatgct tcctcttgca aaaccaatta tgtttgttct
     4681 cttcctttat gcttttgtag gacagtggaa ctcatacttt gatgcaatga tttatatcaa
     4741 ggatccaaac ttggaaccat tgcaacttgt acttcgtaaa attctcattc agagccaacc
     4801 aggtcaagac atgattggag cacaagcggc tatgaatgaa atgaaacgtt tagctgaatt
     4861 gattaaatac gcaactattg tcatttccag cttgccattg attgttatgt atccattctt
     4921 ccaaaaatac tttgataaag gaattatggc tggttcactt aaaggataaa aaaagaaaaa
     4981 ataaaaggag ttttctcatg aaattcaaaa cattctcaaa atcagcagtt ttgttgacag
     5041 ctagtttagc agtacttgca gcctgtggct caaaaaatac agcttcaagt ccagattata
     5101 agttggaagg tgtaacattc ccgcttcaag aaaagaaaac attgaagttt atgacagcca
     5161 gttcaccgtt atctcctaaa gacccaaatg aaaagttaat tttgcaacgt ttggagaagg
     5221 aaactggcgt tcatattgac tggaccaact accaatccga ctttgcagaa aaacgtaact
     5281 tggatatttc tagtggtgat ttaccagatg ctatccacaa cgacggagct tcagatgtgg
     5341 acttgatgaa ctgggctaaa aaaggtgtta ttattccagt tgaagatttg attgataaat
     5401 acatgccaaa tcttaagaaa attttggatg agaaaccaga gtacaaggcc ttgatgacag
     5461 cacctgatgg gcacatttac tcattcccat ggattgaaga gcttggagat ggtaaagagt
     5521 ctattcacag cgtcaacgat atggcttgga ttaacaaaga ttggcttaag aaacttggtc
     5581 ttgaaatgcc aaaaactact gatgatttga ttaaagtcct agaagctttc aaaaacgggg
     5641 atccaaatgg aaatggagag gctgatgaaa ttccattttc atttattagt ggtaacggaa
     5701 acgaagattt taaattccta tttgctgcat ttggtatagg ggataacgat gatcatttag
     5761 tagtaggaaa tgatggcaaa gttgacttca cagcagataa cgataactat aaagaaggtg
     5821 tcaaatttat ccgtcaattg caagaaaaag gcttgattga taaagaagct ttcgaacatg
     5881 attggaatag ttacattgct aaaggtcatg atcagaaatt tggtgtttac tttacatggg
     5941 ataagaataa tgttactgga agtaacgaaa gttatgatgt tttaccagta cttgctggac
     6001 caagtggtca aaaacacgta gctcgtacaa acggtatggg atttgcacgt gacaagatgg
     6061 ttattaccag tgtaaacaaa aacctagaat tgacagctaa atggattgat gcacaatacg
     6121 ctccactcca atctgtgcaa aataactggg gaacttacgg agatgacaaa caacaaaaca
     6181 tctttgaatt ggatcaagcg tcaaatagtc taaaacactt accactaaac ggaactgcac
     6241 cagcagaact tcgtcaaaag actgaagtag gaggaccact agctatccta gattcatact
     6301 atggtaaagt aacaaccatg cctgatgatg ccaaatggcg tttggatctt atcaaagaat
     6361 attatgttcc ttacatgagc aatgacaata actatccaag agtctttatg acacaggaag
     6421 atttggacaa gattgcccat atcgaggcag atatgaatga ctatatctac cgtaaacgtg
     6481 ctgaatggat tgtaaatggc aatattgata ctgagtggga tgattacaag aaagaacttg
     6541 aaaaatacgg actttctgat tacctcgcta ttaaacaaaa atactacgac caataccaag
     6601 caaacaaaaa ctagaggttg attatgggag ataagaaata cacagtagaa aaagccaatc
     6661 gttttatagc agaaaataaa catctcgtta atactcaata taagcctgaa gaacattttt
     6721 cagctgagat tggttggatc aatgatccaa atggatttgt ctattttcgt ggagaatacc
     6781 atctctttta tcaattctat ccatatgata gtgtttgggg gcctatgcac tggggacatg
     6841 ctaaaagtaa ggacttggtg acttgggagc acttgccagt ggcacttgct cctgaccaag
     6901 attatgaccg aaatggttgt ttctcaggct ctgccattgt caaggatgat cgcctctggc
     6961 tcatgtacac tgggcatatc gaagaaaaaa ccggtgtccg ccaagtgcaa aatatggcat
     7021 tttcagatga cgggattcac tttgaaaaga tttcccaaaa tccagttgta actggaacag
     7081 acttgccaga tgagttgatt gctgctgatt tccgtgaccc aaaactcttt gaaaaagatg
     7141 gacgctatta ctccgtagta gctgccaaac acaaggataa tgtgggctgt atcgttctac
     7201 tagggtccga taacctagta gaatggcagt tcgaatccat ctttttaaaa gggggagaac
     7261 accaaggctt tatgtgggaa tgcccagatt acttcgagtt agatgggaaa gattgcctta
     7321 ttatgtcacc catgcgttat cagcgtgagg gagactcata tcataacatc aactcatcgc
     7381 ttttgttcac gggtaaggta gattggggag aaaaacgttt tatcccagaa tcagttcaag
     7441 aaattgatca tggccaagac ttctatgcgc ctcaaacatt gttggacaat caaaatcgtc
     7501 gtatcctgat tgcttggatg cagacatggg ggcgtaccct tccaacccat gaccaagaac
     7561 acaaatgggc atgtgccatg actttaccta gaattctaag attggaagat ggcaaactaa
     7621 gacaattccc tgttaaaaaa ggccaatatc aaatccaaat agataaagat tgtcattacc
     7681 acttaggaaa tgatatagat tatcttgaat ttggttatga cagtaatgcg cagcaagttt
     7741 acattgatcg tagccatctt attcaaaaaa ttctaggtga agaagaacag gacactagtc
     7801 gacggtatgt agatattgaa gctaaagaat tggaagttgt tctagataaa aattccatcg
     7861 agatttttgt caatcaaggt gaagcaagct tgactgcaac ttattactta acggtgccag
     7921 ctgagctatc acgaattgat taaaaattaa gttatttctc ctaaagaaaa agttctcttt
     7981 ctaaaatagt ggaaagagga ctttttgtgt tttgggtata taagcttagt ttatggtatt
     8041 tgtaaaattg gtgttggatt atgatttaaa ctagttttct aaagaatttg aaaaaaattt
     8101 tatttaagca aaaaaaagcc ctatattata agacttttcc tgttgtattt aaatgccccc
     8161 tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca gctgagctaa
     8221 ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc
     8281 aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga cggcctacat
     8341 gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa cacttaagtg
     8401 tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttca aaaaaaatca
     8461 agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt cgatagcttc
     8521 ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga aatagtgatg
     8581 attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat agttgtgtgg
     8641 atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc catcacgtag
     8701 gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct tatccatagc
     8761 tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat tggcaatgag
     8821 aatgcgggct tctgggaacc caatcttctg ggcagcatcc agagcagtca cggtatgaat
     8881 ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca agcgacgagc
     8941 gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac tggcatccac
     9001 atctgagcca cggatagact tttgcagggc agatagaaca tcatagtgac cgtctccatc
     9061 cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta aggtgatgtg
     9121 gcgaatgccc tcgtcattct caggggtaga gagaacagcc aagtccagtg agttaaaggc
     9181 agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct catctagttc
     9241 tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg cctctttgac
     9301 gtcttggtta gacagaggtt ccaactcaaa aatttgaaca cggctacgaa tggcaggagt
     9361 gacggaaaag aaaggatttt cagttgttgc tccaatcatg atgaccagtc cactttccaa
     9421 gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt ctagcaatag
     9481 gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct ttttactatc
     9541 aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat
     9601 actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc ggttggcttc
     9661 caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga tgacctggtc
     9721 gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc tttctagcgt
     9781 ggatttgagt agaatgactc atctactata tcttactatg tccattctag cctattagtt
     9841 gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt ttactattta
     9901 atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct caaaatagga
     9961 tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg aatgtcattg
    10021 tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggaact accaagtcag
    10081 gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca
    10141 gggaaaagaa aacttttctt ccgggaagat actccaaaag agattttaga tttgtacgaa
    10201 aacattaaat ctaaacttga ttttgcttac caagaagttc attctaataa tgggttgaaa
    10261 aaatatgaaa aatagaataa ttgatgtttt tgaagtagta aatcgcctcc ttgtaataac
    10321 tgttgaaaat cctgatttcg aagacttgag agttaatcag tttgtaaaaa ttggagataa
    10381 aaagtataga gtacgcagtg ttcctatgat tcattcaact ccgcctcaat ctgtcttaga
    10441 tcgagatact tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt
    10501 tactactcat tagaaaaata ggtatgaata aattggcttc ccttagaacc acatctaggg
    10561 gcttttatgt ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta
    10621 taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac
    10681 tccttacggc ccatggttgg ataaagacta gaggcggtaa aggctcccat attaaaatgg
    10741 aaaagcaagg ggaaagacct atcacaatcc ttcatggtga gctgaataag tacactgaaa
    10801 gagggataag aaagcaagct gggttgtaaa attcagcccc tgctttttga tatggaggta
    10861 gtgaaatgtt agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag
    10921 cgacttattt tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt
    10981 ctgaggcttt ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga
    11041 gtgatggaga gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc
    11101 cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta
    11161 tggtatctgt tgatgtatca gaatacctag gaagtcagga acccattaaa aagactttga
    11221 ccataccaaa atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt
    11281 tgacagacgc tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta
    11341 atagtcaata aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt
    11401 tattagccct ttcgagggct ttttatattg atttttatga gaaatgaaga aatcagactt
    11461 ttaagaaaat cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa
    11521 aataattttg tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga
    11581 ttaaagagtc gcatagaaag aggacaaaat ggcaacatac ggatttttag atattttaga
    11641 ggaagagttg gacaagaact ttccctttga ctttgagatt agttgggaca agcgtaacca
    11701 cgcggtagaa gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga
    11761 tgaagatgga gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa
    11821 tcctgccaag tcaaccgtca atgcagaaga ctatttaacg gttatccctt atctacctaa
    11881 aaaaggattt tctcgcgagt ttttagctta ttttgccctt ttcctcaaag atactgcgga
    11941 ggttgggcta gataccctca tggacttttt ggaagatcca gaagcagagg aatttgttat
    12001 ggaatggaat caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta
    12061 tccttatcca agatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt
    12121 ggtttatgtg ctagctgttg tctttattat gctagctttt gcttgtggaa caatcgcatt
    12181 tgcagagttg gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct
    12241 aagcatgtat ttaatcttta ttcttcatga gctgggtcat gctttttgtg gctacttgac
    12301 aggctatcgg ctggtggctt ttggattagg acattttatt ttgaccaaaa agtcaggcag
    12361 gtttcatctt agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa
    12421 agaggatgaa agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct
    12481 cggcttgata ttattggcga tagtgtttgg atttttgaca agaagctggt attttgcagg
    12541 gacttggatt tttcttaatt tatctttctt cctaaataac attttgccag tcgacatcac
    12601 cgatggagca aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct
    12661 gatgttgagg cattctgccc agaccttgct agctcctcaa gaatatgatt taaaagactt
    12721 tgttcaagca gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca
    12781 aggtgaagtt tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt
    12841 acttgagagg acaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat
    12901 cgccttgttg gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa
    12961 atcgtttctg tctctcaaac tgtccaatct tcaagtgata caagcttggt atcaatttaa
    13021 ggtaaagaaa gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga
    13081 tagtagtcga atgttgaggg acgagaaacg ctattgtgaa aacttgttag cagagctgga
    13141 aaaggaaatg ttagaaggaa ctgaagatgg aactagaaat ttctgatttc caaggttgca
    13201 agattgccct cttttgtggg gataagctac tgacgatttt gcgtgatgac aaggacgata
    13261 tcccttgtcc caacatgtgg gagttgccag gtggtggccg tgaaggggac gaaagccctt
    13321 ttgaatgcgc tcggcgtgaa gtttatgagg aactgggaat tcatttagat gaagactgtc
    13381 tgctttggag caagatttat cctagcgtaa tttttaaagg caagaaatcg gtctttatgg
    13441 ttggtcagct aagacaagaa caatttgaca atatcatctt cggagatgaa ggacagggct
    13501 ataaattgat gcctattgag gaatttctca attctaaaca ggcagtgcct cagttgcagg
    13561 gaagattgag agattatttg gaggaaagtt tatgataaca cttgttcgag cgggagcaga
    13621 ggatttagaa actattattg caattcagag agccagcttt aaggctgttt atgaaaaata
    13681 ccatgatgaa tatgaccctt atctcgagga ctgcgaacga attaagtgga aattagtcga
    13741 gcgtcccaat agctattact actttgtaaa agaagatgaa gaaaacatcg gatttttacg
    13801 agttcagacc aatgccgagt taacgaaagc ttggttggga acggcagcga ttttgcctca
    13861 gtatcaagga aaagggtatg gatctaaagg tttaagctta ctggaaaaag aatttccaac
    13921 catcacacaa tgggatttgt gtacggtgtt acaggatgca ggcatggttg ctttttacga
    13981 gaaaaacggc tatcgtcaaa tccacattga ggctgaaaaa gaaggcatgg atatggtcta
    14041 catgaaaaaa ttgatagaga aatagaaagg atggttcggt taaatttcta aactgaaccc
    14101 gccctaaaca cggtgccaaa aagataaact tctcttagac acaaacgtct tcagagagtt
    14161 tcctattttg gctttgtgtt ttacgggctt ggtatcttaa taatggaaac atggcaagag
    14221 ttaaaagtta cagtgaagcg tgagggagag gagttggttt ccaatctctt gattgagtta
    14281 ggtgcccaag gggtagcaat tgaagacagc atggactatg tgggaaatgt ggaccgattc
    14341 ggtgaaattt tcccagaggt ggagcaacag gaagaaatcg tagtgaccgc ctactaccct
    14401 gaaacggttg atgtagcagc agttgaagcg gatttgcagg ctcgtctggc agaattgacc
    14461 gactttatgg acctaggaga agtcaagatg ggcacgactg ccttggctga ggaagactgg
    14521 gctgacaact ggaagaagta ttatgaaccg gcacgcatca cccatgacct gaccatcgta
    14581 ccgtcatgga cggactatga ggcaacagca ggagaaaaga ttatcaagct ggatcctggt
    14641 atggcctttg ggacagggac ccacccaaca accaagatga gcctctttgc cttggaacag
    14701 gttcttcgtg gtggcgaaac agtgctagat gtagggactg gttcaggggt tctttctatt
    14761 gcaagctcac tcctaggtgc caaggagatt ttcgcctatg acttggatga tgtggcggtt
    14821 cgtgtcgctc aggaaaatat tgagctcaac actggtatgg aaaatatcca tgtagcagca
    14881 ggagacttgc ttaagggagt tgagattgaa gcagatgtca tcgtggctaa tatcttggcg
    14941 gatatcctca ttcatctaat agacgatgcc tatcgtttgg tcaaggacga aggctacctg
    15001 atcatgagtg gcattatcaa ggataagtgg gacatggtgc gcgagtcggc tgaatcagct
    15061 ggatttttcc tcgaaactca catggttcaa ggggaatgga atacctgtgt ctttaagaaa
    15121 accaaggata tctctggtgt gattggaggc tagcatgcag cagtattttg taaaaggcag
    15181 tgctatctct cctgtcacta tcgaggacaa ggaaaccagt aagcatatgt ttcaggttat
    15241 gcgcttgaaa gaagaggatg aggttacctt agtctttgat gatggcatca agcgcttggc
    15301 gcgcgtgctg gatatggaaa atcgtcagtt tgagttggtc caagaattaa atgacaatgt
    15361 ggaactacca gtccaagtga ccatcgcatc tggatttccc aagggagaca agctggagtt
    15421 catcgctcaa aaagtaaccg aactgggggc tagccaaatc tgggcctttc ctgcagactg
    15481 gtcagttgcc aagtgggatg gcaagaaatt gggtaaaaaa gttgaaaaac tagaaaaaat
    15541 tgcccttgga gcagccgagc aaagcaagcg taatattgta ccaagtatta aacttttcga
    15601 gaaaaaagca gattttctag ctcagctgga ccagtttgac tctatcatag tagcctatga
    15661 agaatcagct aaagaaggag aagccgctgc gctcttacaa gcggtctctg gtcttgaaac
    15721 aggagccaaa ctgctcttta tctttggacc agaaggcggt ctctcacctg cagaaatcga
    15781 aagttttgaa gctaagggag ccgttttggt aggcctaggt cctcgtattt tgcgagcaga
    15841 aacagcaccg ctttacgcct tatcagccct tagtgtttta gtagaattag agaaataaga
    15901 ggaagaaaat ggaacaaaaa caccgttcag aatttccaga gaaggaactc tgggacttaa
    15961 cagccctata ccaagaccgt gaggatttct tgcgtgcaat cgagaaagct cgcgaagaca
    16021 tcaaccagtt tagccgtgat tacaagggca atcttcacac ttttgaggat ttcgagaagg
    16081 cctttgcgga attggaacag atctacattc agatgagcca tattggcaac tatggtttta
    16141 tgcctcagac gacggactat agcaatgacg aatttgccaa tattgcccaa gctgggatgg
    16201 aatttgaaac agatgccagc gtagccttga ccttctttga cgatgccttg gtggtagcag
    16261 acgaggaagt cttggaccgt ttgggtgaat tgcctcactt gacggcagct attcgtcagg
    16321 ccaaaatcaa aaaagcccac tatctagggg ctgatgtgga gaaggccttg accaatctcg
    16381 gtgaagtttt ctatagtccg caggacattt atactaagat gcgagctggg gattttgaaa
    16441 tggctgactt tgaagcccat ggcaagacct acaaaaacag ctttgtcacc tatgagaatt
    16501 tctaccaaaa tcacgaggat gccgaggttc gtgagaaatc cttccgttcc ttctcagagg
    16561 gacttcgtaa gcaccaaaat acggctgcag cagcctatct ggctcaggtc aagtctgaaa
    16621 aactcttggc tgatatgaag ggatacgact ctgtctttga ttatcttcta gctgaacaag
    16681 aagtggaccg tgtcatgttt gatcgccaga ttgacctcat catgaaggac tttgcaccag
    16741 tcgctcagag atacctcaag catgttgcca aggtaaatgg tcttgaaaag atgacctttg
    16801 cagactggaa attggacttg gacagcgccc tgaatcctga agtgactatt gacgatgcct
    16861 atgatttggt catgaagtcg gtagaacctt tggggcaaga atattgtcag gaagttgctc
    16921 gttaccaaga agagcgctgg gtggactttg ctgctaacag tggcaaggat tccggtggtt
    16981 atgcggcgga cccatatcgc gtacaccctt atgtactcat gagctggaca ggccgtttga
    17041 gcgatgtcta taccttgatt catgaaatcg ggcattctgg tcaattcatc ttttcagaca
    17101 atcatcaaag ttacttcaat gcccatatgt cgacctacta tgttgaagca ccgtcaacct
    17161 tcaatgaatt gctactcagt gattacttgg agaaccagtc taatgaccca cgtcaaaaac
    17221 gcttcgctct ggctcatcgc ttgacagaca cctacttcca taactttatc acccacctct
    17281 tggaagcagc cttccagcgt aaggtgtata cattgattga agaaggggag acctttggag
    17341 caagcaaact caacagcatt atgaaggaag ttttgacaga tttctgggga gatgctattg
    17401 aaattgatga tgatgcagct ttgacttgga tgcgccaagc tcactactat atgggcttgt
    17461 atagttacac ctactcagca ggactagtca tctcgacagc tggttacctt catcttaaaa
    17521 actcagaaac tggagctgaa gactggctta atctcctcaa atcaggtggt agcaagacac
    17581 cacttgagtc agccatgatt atcggtgctg atatttcaac agacaaacca ctccgtgata
    17641 ccatccaatt cttgtctgac acagttgacc agattatcgc ctacagtgct gagttggggg
    17701 agtaagggga tagagaggtt gttatagaat gggtatggac agttatttgc ttaaaagtcc
    17761 atgtttaaat cccccattcc ttttcgagga attctttgcc cttctctgta atggtaagtg
    17821 aacgtggcgt ttgtgcaggg atgaccaatt gtttttcact gaaaaattct aaaagagcat
    17881 tgccgagagc tccgccgaca tgatttttac gttcgctcca atccaaacat ttagggcaaa
    17941 atttccgttt tttctttttc aattcatccg tatcaatgtg taattttctt tggaaataag
    18001 acttcccagc ttcagtgagt tggaagtctt tttctgattc gctgaggaga ttttcttgca
    18061 agagataatt ggtaatggaa atgccaagct caccagcaat atggtcatag caggtgcgag
    18121 cgacctttaa ttcctttttg tgaatgtgtt gtttataact tttgacatca cgctgaggag
    18181 agtagaagct gagaaattcc agcatttctg caatggcagc actttttaaa gaataataat
    18241 gaaaacgtcc ataggtttgt agagtggtta cctgcgcttc ggtaagtaat ttgaggtgat
    18301 agctgacagt atgttgcttg attttggtaa agctggcaat ttcgttaacc gtgtgagctt
    18361 ttccatccat tagaatatct aaaatgtgca tccgagaagg gtctgataag agttttgtga
    18421 tgatgaaaat atctggttcc ataaaaattt tctccaaatt tcatatatcg attattttct
    18481 atcttttatt atactataat taaagcacaa gaaaaataga ttttaaaaat gttttactag
    18541 agaatatttt aaattttatt gtctgagttt aaatggaggt aaaattacaa aagtaattgc
    18601 agcagtatcc acagttgaag gacgttaatc ttaagattac attctcaaca ttttttcaaa
    18661 agtgagatga attaacaaag tatcgaacat gctctatttg tgggggaaag aaagagtgaa
    18721 gaagttaagt gttaaaaatc taaaaaagca atatggttct tatgaagctg tcaagggaat
    18781 tagctttgaa ttgggagaag gagagtgttt gggtatcttg ggaatcaacg gtgctggcaa
    18841 aacatccact ttaaagatga tttactcact gacctcaatt tcctcaggag agattgatat
    18901 cttggggcaa aatattgaaa ccaatcgtcg taagagtaaa tcttgtctgg gtattgtagg
    18961 gcaggaggat atgctggata tgaccttgaa tgtttatgat aatctttttg ctcacggtct
    19021 atgttatggt atctcatctg tcgaacttag gaagagaatc gattctctct tggattttgt
    19081 tcaactgagc aaacatgcgc aaaagatggt gaatcagctg tcgggtggga tgcgacgacg
    19141 tcttgtcttg gcaagagctc tcatcaatcg gcctgatatt atcattttag atgaaccgac
    19201 agttggttta gacattcaat cccgcaatat tatttgggat aaacttttgg agttgaagga
    19261 attaggtgtt tctatcatta ttacttccca ctatatgaat gagattgaat atttgacaga
    19321 tagggtgctg atgctccacc aagggactat caaagaagaa ggaactgtag aagacttgct
    19381 catcaagtat gatgctgaca accttgagac gctttttttg gggttgactg ggacagagaa
    19441 ggaggacttg catgtttaag ttatcatttc agtccatcgg acacgttgtg gtacgcaact
    19501 acatgagttt tagaaattta tttaaaattt caattgtccc caaccttatc gaccccctct
    19561 tttatctttt agcaatggga tttggagttg gtgcctactt gacgcatgtt aacggtatgc
    19621 tctaccgtga ttttgtcatt acaggtttaa ttgctgcgac tgccatgtct gcggccaccg
    19681 cagaaacaac ggtcaatgcc tttatccagt ataagattga aaagacttat gatgctatgt
    19741 tgatgacgcc aatcaatacg agtgatattg tggtgggtca ggctatctgg gcaggtattc
    19801 gtgcagtgat tttcggtggg attttttggc tgatttccat gcttatcaca gcgcattttc
    19861 atgtcttgat gttattgatt cctctgattt tatttatagt gggttatttg tttggtgttt
    19921 taggactaat ctttacctac ttggcaccgt ctagggaatt tctgaattac tacaatgttt
    19981 tggtaatccg tcctctttat atgttttcag ataccttctt tcccattact tccttgcccc
    20041 caatacttgg tgatttgact tggttttctc ccttgtatca cgctacccgc atgattcgta
    20101 ttatatgggg aggtgaggtg acaggtttgt atcttcatct tatctggttg atagccttgg
    20161 cgctcttgat aacggtgctt cctatgtata tgttacatcg tagatattat agatagtcta
    20221 attatttgtg atgttgtagt catattctaa tttatactaa acgttattcg aatttggaca
    20281 ggtatgggaa ctgtgcctat caatattgta atttatggaa gttgaaatag tacggttcag
    20341 tttttaaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    20401 tcactttatt ataactagtt tttcgcaatt tttgagacag aaatgtgatt tttgtgataa
    20461 agttctatca ttacaagttc atttgtggta atatggaata aatcatttat gtatcctttc
    20521 agaaatgtgc tgtttctctg aatataaatg tctttttctc tttaacttaa ttttacaaat
    20581 tgctaaagtc atttaaggac agctttttga acagttgcta gaaatgtaga ggtattgacc
    20641 atgtatcaaa agttacttag aaaaatagca gaagaaaaac caagttataa ccaggaagaa
    20701 atccagtggc tacttgatca tttgggagat ccttctccag aaattcgtga tgaccttgtt
    20761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggaaca atttcatttc
    20821 attgctgaag ggatttcatc tgatggaggg ttagataaag atattgataa ggtaggcctg
    20881 tcaacccttg aacgttcttt tagggcgctt atttatgcaa atctcttgtc tgcagatgcc
    20941 aaccagcaat cgatttttat caggaattaa atgcaggaat tcgtaatgtc cttttaaatc
    21001 aaggtttgta ttatctttca aaagaaaagg atacaacggg tttttcaagt cagtatggtt
    21061 gggttcatgc ttttgcacat ggagccgatt tactgacaga ggtggtttgt catcccaact
    21121 ttcctaaaaa cagagttcat gaagtatttg atatacttgg ccaactattt aaaagagttt
    21181 cgattcgctt tacagatgat gaggattggc gtttagcaag agtgatctat gaacctattt
    21241 tacaagggaa gttagcgcaa gagcaagtag cttcttggat aaaagctgtt gactttccga
    21301 tagaagaaag agaagatttt tataaatttt ccaacttcag atcctgtctg ttggaagtct
    21361 atgttcaact tgaccagaga aatagtttac aagatgactt gaaagaagct atccagtctt
    21421 ttcaatacta agaaaaagcg agtcagattt tcaaaaaact ttccaagcaa ttttcttgaa
    21481 accctttccc tcttttgata gactagtatc tagtttttga aaaaaggaga aagaaaatga
    21541 aaaaatttgt tgctgagtta atcggtacgt tcatgcttgt gttcatcgga acaggagctg
    21601 ttgtttttgg aaatggtttt gatggccttg gtcaccttgg aattgctttt gcctttggtt
    21661 tggcaatcgt agtcgcagct ttctcaattg gaactgtttc aggtgctcac ttgaacccag
    21721 ctgtttcgat tgctatgttt gttaacaagc gtttgtcatc aaaagacctt gtaaactaca
    21781 tccttggaca agttgtcgga gcttttattg cttctggcgc tgtcttcttg ctcttggcaa
    21841 attcaggtat gtcaactgct agtcttggtg aaaatgcttt ggcaaacggt gtcactgtct
    21901 ttggtggttt cttgtttgaa gtcatcgcaa ctttcttgtt tgttttggtt atcatgactg
    21961 tgacttcaga aagtaaagga aatggcgcga ttgctggttt gataatcggt ttgtccttga
    22021 tggcgatgat ccttgtcgga ttgaacatta ctggactttc agtaaaccca gctcgtagct
    22081 tggcaccagc tgtcttggta ggcggcgcag cccttcaaca agtttggatt ttcatccttg
    22141 caccaatcgc tggtggagtt cttgcagccc ttgttgcaaa aaatttcctt ggaacagaag
    22201 aataattgaa actcaaaaag ccttgctcct catcttgagg aacagggctt tttcgtatga
    22261 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgccgtaggt atggttactg
    22321 acttcgtcag ttctatctgc aacctcaaaa cagtgtttta agctgacttc gtcagttcta
    22381 tctacaacct caaacactgc tttgagtaac ctgcggctaa cttcctagtt tgctctttga
    22441 ttttcattga gtatgacttt agcggttgtc aattttctct ggataaaggt cgtgttggaa
    22501 gaggcgttgt tctgccaagc cctcatactt agttccttgc ttaccgtagt tgtagtaggg
    22561 gtcgattgaa atgccaccgc gcggagtgaa tttcccccag acttctaaat agcgagggtc
    22621 tagcaagttg accaagtctt tcccgatggt gttgatacag ttttcgtgga aatctccgtg
    22681 gtttcggtag ctaaatagat atagtttgag ggattttgac tcgacacaga gcttgtcagg
    22741 aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca gtgatttgtc ccagcagaga
    22801 catatcgagg atatggtgac gaatgccctg ttccttagcg atttctctat taatttgaat
    22861 ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct tcgactgttt catagtgttg
    22921 catggcccag aaaaggcagg ttgttgaatc ttgaccacca ctaaagacga ccaaggctga
    22981 ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc agagcatgca aaaagctccc
    23041 attagggagc taaaaaatac caaatcgagt ttttttagcg atggcatatc ccaaacatcg
    23101 taatattcta cttatatagt aaaatgaaat aagaacagga caaatcgatc aggacagtca
    23161 aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctgctat
    23221 agtctagcat attttttgaa aaatggcaaa gggcaagaaa aaagagacca aagaaagtac
    23281 ttggtctctc gtttgattag ctcaattcag caatgatggc cttgatttgt tctgctgtgt
    23341 gaacacctgc aacctgtttg acaacttggc cgtctttttt gaagagaaga gttggaatag
    23401 acatgattcc aaaagcacga gctgtgtttg gattttcatc aacgtccatt ttaacgattt
    23461 tcaagacatc ttctgaaagt tcttcagaca atttgtccaa gattggacct tgcatacgac
    23521 atggaccaca ccaagttgcc cagaagtcta ctaagaccaa accgtctttt gtttcttgtt
    23581 cgaatgttgc atctgtaatt gcttttgcca ttgtatttct ccttttttta gttatattgg
    23641 cttaaatctt gtttcatgag atagaagaag atatctccat aagtcccatg gtagtccaaa
    23701 ttatggccct tgtaagttaa tttttggaca gggtagtagt ctgcgacgcc gataaggcaa
    23761 gcttgttgcg aacgttcaaa gtcttcataa gactcgaaag tcacagttct ttcgttcttg
    23821 ctggcatcta tataggtaat ttcaatcata tttaaaactc ctttgtttaa tgctaacttt
    23881 attttactcc ttataaaaga gaatgtcaag aaaaatgatt gcgcacgcaa ctttttttaa
    23941 aatcatctta aatcaagaaa tccaaacctg cttccaagct ttcttcgaca gtcttttgta
    24001 gcgaggccag tgtcttttgc ccatcatttg tcaggcagat aaaactagag cgtctatctt
    24061 gatggcaaca tatgcgactg agtagaccgc aatttttagc ttccaagcga gccaccatcc
    24121 tagaaactgc gctcgggctc agatgaagct tatctggcag gtcaatctgg cgtagagatt
    24181 tttcttcagc caagtccaga tagtagagca ggtagaactc tttcaaggtc agactttgct
    24241 cgctctgttg ggcaatggtc tcttccaaga gactttcaat ttctttctga cgccgattga
    24301 agtcaaacca tttttccaaa taggtcatag tgtctccttt ctttttagag tcataaaata
    24361 gaagaaagtc cattaacggg cagtctctgc gtcacaagat gattgcgcat gcaataatta
    24421 tactactttt caagaatgct ggcaagctct gttttttagt ggttttattt tttactgtcc
    24481 atatttttgg taaaaatcaa cttttacttg gatgaaggtt ttggcttcac gtaggagttg
    24541 aagaagggtg gcgcgggttt caaactcttc tcttgtcttg ggcagactgc ggttccggaa
    24601 gacttccaga taacgttcaa tttcatctag caaatcagaa gcaggattgg tctggctcag
    24661 ttgacctgca atttttgaaa agagttgcgc taagatcagg ctttcactgg cggcaaggtg
    24721 acaagtgtta atctgttggg ccatgtttct caggatacga ctttgtcgtt gtctcatctc
    24781 aaagtagtgg atatggtagt cggtctggtg aaagaggtgg tcagagtgat ccaaatagac
    24841 cagtctgagg gcttctttca aaagcgtgtc taattctgct accagctgtg ctcggttgcg
    24901 tccgtctcct ctggataaat agtatttgaa gcgctggagg atatctttta acttttcttc
    24961 caccagcgtg tggtagtgct ggatttcctc ttctcgtgaa ggcatataga gattaacaag
    25021 caaggcaaat cctgtaccaa tagcaaagag aaggaattca ttgactagaa ggtctggaga
    25081 ggttgactct tgaaccaaga gatggctaac caaaacagtg cttggtgtga tgccaatttc
    25141 ccagcccatc ttgtaggcta aaggaacgta gaaggccaga tagaggccga gactccagat
    25201 atgaaatccg ctcaagtgaa aagctagaac accgatagcc agagctagaa gcatagaaaa
    25261 aagacgattg cgagccagtt ttaaagtact tctacgcgta tcagataggc tcaagagagc
    25321 gataattcca gccgaaactg ctgatgaaag attgagaaaa taagcaagca ggcaggcaag
    25381 acaggtagct aagatgagct tggtcgtacg ttggctaata gacataagaa tttcctaata
    25441 agttagaata aaagcgtaaa agacaagaca tgagcaggct tgccttgatg agttattttt
    25501 tacgggttgc tgcgtattcg gcaacggcgg taaagaggac atctgtagaa gagttaaggg
    25561 ctgtttcaca tgagtcttgg atgacaccaa tcacaaaacc aaccccaaca acttgtatgg
    25621 caatatcgtt agaaataccg aaaaggctac aagcaactgg gataagaagg agggaacctc
    25681 cggcaatacc tgaagcacca caggctgaga tagctgctac cacactgagg acaaaggctg
    25741 tggcaaagtc aacaggaatt ccaagagtgt taactgcagc aagggtcaaa acgttaatgg
    25801 taatcgctac tccagccata ttgatagtag aaccgagtgg gatagaaaca gaataggtat
    25861 ctgggttgag tccaaggtca tggcagagtt tcatgttgac aggaatgtta gccgcagaac
    25921 tacgagtgaa aaaggctgtc acaccgctga cacggaggca gttccaaact agagggtaag
    25981 gattacgtct cataaagaag aaggcaatca aagggtgacc acaagggcaa caaaaagcat
    26041 agtcgttact aatagaacca ataaaatacc gtagttggca aggcttccga ctcccttgtc
    26101 agaaatggtt ttaaaaacaa gaccaaggct tccaaatgga gccagattga tgatccattc
    26161 gacaatttta gaagtcacgt cagcgatagt ttttagcaat tctttactat ttttactggc
    26221 ttctctcata gcgattccaa aaatgactgc ccaagataag attccaatat agttagcagt
    26281 aaacagggcg ttgactgggc tgtcaaccag tttgagcaag aggttgctga gaacctgccc
    26341 aaccccatct ggtggtgcaa tttcagtatt ggcactattt agggtaattt caatagggac
    26401 gatgaaactt gctagtacag ctacaagagc agcggcgaaa gtccctatca taggatatac
    26461 aagaaaacaa cagttttcat attgctatct tgtccctttt gatgttggga aagggcattg
    26521 gcaacgaggg caaagactag gataggagca acagctttta gacctccaac gaataaatcc
    26581 ccgagtagcc caatccctga gagattagga agggtcagtc ctaggattcc ccacaaagca
    26641 taccaatcaa gatacgcttg acaaggcttg ccttattcca agcatgaatg attcttttca
    26701 taataatctc ctttttgtgt agtgattatg attatagtat aaatgataga caaaatcaag
    26761 aattttctgt ctattttttg aatatttatg gagaatgaga ctgatgaaaa tatggtataa
    26821 tgaaataaag gagttttata tgcaaaaatt tattcaggct tatattgaaa agctagatgt
    26881 gacaaccatt atcgagaata ttctaaccaa ggtcatttct cttttactgc ttttgattgt
    26941 attttatatt gctaaaaaaa tgcttcatac catggtgcag agaattgtca aaccttctct
    27001 aaaaatgtct cgtcatgatg tcggacgcca aaaaaccatc tcacgtttac tagaaaatgt
    27061 gtttaattat acgctatatt tctttttact ctactgcatt ttgtctattt taggtttgcc
    27121 agtttctagt ttgctggctg gagctggtat tgctggggta gcgattggta tgggagccca
    27181 aggctttctg tctgatgtca tcaatggctt tttcatcctc tttgaacgtc aactggatgt
    27241 gggagatgag gtcgttctga caaatggacc gattactgta tcgggtaagg ttgtcagtgt
    27301 gggaattcgt acgacacagc tgcgtagcga ggagcaagcc cttcactttg tccctaaccg
    27361 aaatatcaca gttgttagca atttctcacg cacagactag acctgttatt ttaagtaatt
    27421 tgtggtacaa tagagggagt ttaataagga gaaaagatgg ttttagaaaa gcagttgggc
    27481 aatggttgta cctggataga cctagaccta ggaaagttga ataaactaga agacctttct
    27541 gaaatttacg gtttggacaa ggaaaccatt gaatacgcac tggatagaaa cgagcgcgcc
    27601 cacatggact accaccgtga aagtgggacg gttaccttta tctataatgt cctagacgta
    27661 aaaaaggaca aggcctacta tgagactttt cccatgacct ttatcgtcga gcatcgtcgc
    27721 ctgattacca ttagtaatac caagaacgcc tatgtcattg aacagatgac tcgttatctg
    27781 gagagccatg acacgctttc gatttataag tttctctttg ccagtctgga aatcatcagc
    27841 aatgcctact atcctgtcat tgagcagatg gacaagagta gggatgaggt caatgacctc
    27901 ttgcgccagc gaactaccaa gaaaaacctc tttgccctgt ctgatttgga gactggtatg
    27961 gtttatctga cggcagctgc caaacaaaat cggattttgt tagagcatat tcaaggtcat
    28021 gccttgtatc gtagttttga tgagattgag agagaacagt ttgatgatgc tatgattgag
    28081 gctcatcagc tggtatccat gacagaccta atctctcaga ttttacagca gctttcagcc
    28141 tcttacaaca atattctaaa caataatctg aatgacaatt tgacaacctt gactatcatt
    28201 tcagtcttgc tagctgtttt ggcagtcgtg acaggctttt tcggaatgaa tgttccctta
    28261 cctttaacag atgagcccca tgcttggctc tatatcagtt tggctagtgc aggtttgtgg
    28321 attgttttat ccttgttact aaggaaaatt gcgaaaaaaa gttaagaaaa ggagccagaa
    28381 tggcgattga aaattatata ccagattttg ctgtggaagc agtctatgat ctgacagtcc
    28441 caagcctgca ggcgcaggga atcaaggctg ttttggtcga tttggataat accctcattg
    28501 cttggaacaa ccctgatgga acgccagaga tgaagcaatg gctacatgac cttcgggacg
    28561 cgggtattgg cattatcgta gtgtcaaata acaccaaaaa acgcgttcaa cgagcagttg
    28621 agaaatttgg gattgattac gtttactggg ccttgaagcc cttcacattt ggtattgacc
    28681 gtgccatgaa ggaattccac tatgacaaaa aggaagtggt catggttggc gaccagctca
    28741 tgacagatat acgagcagcc caccgtgcag ggattcggtc aattttagtc aaacccttgg
    28801 tccaacatga ctcaatcaaa acgcagatta accgaactcg tgagcgtcgt gttatgagaa
    28861 aaatcactga aaagtacgga ccgattacat ataaaaaagg aatttaacta tggaagaaat
    28921 tctctgtatt ggttgtggag caaccattca gacgacagat aaagctggtc ttggttttac
    28981 cccccagtcg gcacttgaaa aaggtttgga gactggcgaa gtctattgcc aacgctgttt
    29041 ccgtctccgc cactacaatg aaatcacaga tgtccagttg acgaacgatg atttcctcaa
    29101 gctcttgcac gaggtgggag acagtgatgc cttagtggtc aatgtcattg atatctttga
    29161 ttttaatggc tctgtcatcc caggtttacc acgtttcgtc tcgggcaatg atgtcctctt
    29221 ggtaggaaat aaaaaagata tcctccctaa gtcagttaag tctggtaaga ttagccagtg
    29281 gctcatgaaa cgtgcccatg aagaaggtct tcgtccagtc gatgtggtcc taacttcagc
    29341 acaaaataaa catgccatta aggaagtcat tgacaagatt gaacactacc gtaagggccg
    29401 cgatgtctat gtggtcggtg tgaccaacgt tggaaaatca actctaatca atgctattat
    29461 ccaagaaatc acgggtgatc agaatgtcat cactacttca cgcttcccag ggacaacctt
    29521 ggacaaaata gagattccgc ttgacgacgg atcttatatt tacgatacgc cgggaattat
    29581 ccaccgccac cagatggctc actacttgac ggccaaaaac ctcaagtatg tcagtcctaa
    29641 aaaggaaatc aagcctaaga cctatcagct taatcctgag caaaccctat ttttaggtgg
    29701 tttgggacgc tttgacttta tagcaggaga aaagcaagga tttactgctt tctttgataa
    29761 tgaactcaaa ctccatcgta gcaagcttga aggagctagt gctttctacg ataagcacct
    29821 gggaactctt ctgacaccac caaatagcaa ggaaaaagaa gatttcccaa ggctagtcca
    29881 gcatgtcttt accattaaag ataagacaga cctagtcatc tcaggcctag gttggattcg
    29941 tgtaacaggc atagcaaaag tcgccgtctg ggcaccagaa ggcgtcgccg tcgtcacacg
    30001 aaaagcaatt atttaagcac agaaaggaaa gggttgtctg aatttgggcg agcaaggcga
    30061 gccccataga gaatactttt cgctgtggtg taagttggta caagtgattg taccaactgc
    30121 ggaaaatttg agaccttagg ctcaaatttt agtcatgaaa gtccgaagga ctttgctgac
    30181 gtccgtcacc acttcagaaa agtataaaaa gaaactcttt taaagaaatt atgtcattaa
    30241 catcaaaaca acgtgccttc ctcaacagcc aggcacacac cctcaaacct atcatccaaa
    30301 tcgggaaaaa tggactcaac gaccaaatca aaaccagcgt ccgtcaagct cttgatgcgc
    30361 gtgaattaat caaggttact ctcttacaaa acacagatga aaacatccac gaagtagctg
    30421 aaattttgga agaagaaatc ggtgtggata cagtccaaaa aataggacgc atcttgattt
    30481 tgtttaaaca atctagcaag aaagaaaatc gcaagatttc taagaaagtc aaagaaatct
    30541 aagaccgaaa ctccaaataa ctgtttttat agagaaataa aggggactag cctatgacaa
    30601 tcgaactatt gactcccttt accaaggtag agttggagcc agaaatcaag gagaaaaaac
    30661 gcaaacaagt tgggatttta ggggggaatt ttaaccctgt tcacaatgcc catctcattg
    30721 ttgcggatca agtacggcaa cagttgggac tggatcaagt tcttctcatg cctgaatacc
    30781 aacctcctca cgttgataaa aaggaaacca tccctgaaca ccatcgtctc aagatgcttg
    30841 agttggcaat tgagggaatt gacggcctag tcattgaaac cattgagttg gagcgcaagg
    30901 gtatttccta cacctacgac accatgaaga ttttgacaga gaagaatcca gatacggatt
    30961 attactttat catcggtgcc gacatggttg actatctgcc taagtggtac cgaattgatg
    31021 aactggttga catggttcag tttgtggggg ttcagcgtcc acgctacaag gcagggactt
    31081 cctatccagt tatctgggtg gacgtaccgc tcatggatat ctcgtccagc atggtgcggg
    31141 acttcattgc ccaaggtcgg aaacccaact ttctcctacc tcagccagtg ctagactaca
    31201 tcgagaagga ggggctctac tgatgtccta tcaagactat atcaactgct cccgtgaggc
    31261 cttgttggaa aaaatggcag agcttctacc tgagaaacgt ctaacccatt gtctaggtgt
    31321 ggagcgtgcc gctatggagt tagctcagcg ctttggtgta gatgttgaga aagcaagtct
    31381 agcaggtctt cttcatgact atgctaaaaa gttgtcagat caggaatttc tagacttgat
    31441 tgaccgttac cagctagacc ctgacctcaa aaactggggt aataatgtct ggcatggtat
    31501 ggtcggaatt tacaaaattc aggaagattt ggatttgcat gattcagaaa tcctgcgagc
    31561 cattgaagtc catacagtcg gtgctggtca aatgacagac ctagataagg tcatctacgt
    31621 cgcagactat atcgagcaca atcgagcctt tcctggagta gatgtggcgc gtgagattgc
    31681 aagtctatcg ctcaataagg cggtggccta cgaaacagct cgtaccgtgg agtatctagc
    31741 tcatcaggga ttccccatct atccccaaac ccttgaaacc tataacgcct ttgtgcacta
    31801 tttgaaagag aactaaatga agacggcttt tataatcatt gatgttcaga atgttttagt
    31861 agaaactggg ttccagacaa aaagtctatt gggaaaaatt tcttatttac aaaaccaggc
    31921 tagaagcaag aatattgaaa ttatctatgt tcaacatatt gagaactctg aagctcaaac
    31981 atcagaagat tggcagttat ctgcgctttt aaatcgaaaa cctgctgaaa aggtctttca
    32041 gaagaagtat aacagtattt tcaaagaaac tggcttaaaa gaatacttgg ataaacaggg
    32101 gattgaaaaa ttagttttat gtggtatgca gacagaatat tgtgtggata cttctgtcaa
    32161 ggttgccttt gaatatggct atcagcttat tgttccagaa ggtgctgtca caacctttga
    32221 tggggatgac attccagcag aaacgattaa tgaattttat gaggacattt gggaggagcg
    32281 ctttgcagat gtcctagatt acaaacatat tttctaaaaa gaggattaaa tgaacgaaaa
    32341 agaattacta gaactagtcg tgaaagcggc tgatgagaaa cgtgcggagg atatcctcgc
    32401 acttgatgta caagatttga ctagtgtgac ggactacttt gtcatcacta gctcaatgaa
    32461 tagccgtcag ttggacgcta tcgcagctaa tatccgtgaa aaagtagctc aagcgggctt
    32521 taaaggtagc catgtcgaag gcgatgcagc tggaggctgg gtcttactgg acctcggtgc
    32581 tgttgtcgtg catatctttt cagaagaaat gcgtgcccat tataatctag agaagctatg
    32641 gcatgaggcg gattcagtag atatttcaga agctcttgct tagaagatga actcagttgt
    32701 agtcaactgg gtttctttgc ttattttaga aaattgatgg aaaggtaaag agcgagtggt
    32761 gtttgccatg gaggctcttg gtatcatgat tatggcaact tatgaaacct ttgcggcggt
    32821 ctatgatgca gtcatggacg atagtttata tgataaatgg acggattttt ctctgcgtca
    32881 cttgcctaag accaaggaga gaaagaaact cttagaattg gcttgtggga caggtattca
    32941 gtctgtacgc ttttctcaag ctggttttga tgtgactgga cttgatttga gtggggatat
    33001 gttgaagatt gccgagaaga gagcttcttc agccaaacaa aagattgatt ttattgaagg
    33061 caatatgctg gatttgtcca agtcaggtca atatgatttt gtcacgtgtt actcggactc
    33121 gatctgctat atgcaggatg aagtagaagt cggggatgtt tttaaggaag tgtataatgt
    33181 gctcaacgaa gatggtgtct tcatctttga tgtgcattcg acttaccaga cagatgaggt
    33241 cttcccaggt tattcttacc atgaaaatgc ggaagatttt gccatgctct gggatacata
    33301 tgaggacgaa gctcctcact ccatcgtgca tgagttgact ttctttatca aggaggctga
    33361 cggttccttt agtcgccacg atgaagtgca tgaggagcga acctatgagg tcttgaccta
    33421 tgatattttg ctggaacagg ctggattcaa atccttcaaa ctctatgcgg actttgagga
    33481 caaggaaccg acagagacaa gtacccgttg gttttttgtc gcgcagaagt aggagattag
    33541 catgaccatc acaggtatta ttgcggagtt caatcctttt cataatgggc acaaatacct
    33601 gctggatcag gctgaggggc tgaaaatcgt tgccatgtca ggaaatttca tgcagcgtgg
    33661 agagcctgct atcgtggaca agtggacaag ggcccagatg gcactggaaa atggcgcaga
    33721 cttggtagtg gaattgccct ttttagtcag tgttcaggcg gcagatttct ttggccaagg
    33781 agctgtggat atcttggctc gattgggcat agatagcctc gcttttggaa cggaggaagt
    33841 tctggattac cagaaaattg ttgacttata cacagagcga ggtgctgaga tggagagttt
    33901 tgtggaaaat ctgcctgatt ccctttccta tccccagaaa acccaggcca tgtggaagga
    33961 atttgcaggt cttgattttt caggaaatac gcccaaccat gttcttgctc tggcctatgc
    34021 caaggcggtt gcgggacgaa acatcaagtt gcatccgatt cagcgtcagg gggctggcta
    34081 tcattctgtg gacaaggatg tggactttgc ctcggcgaca gctctgcgcc agcatcagtc
    34141 agaccaagat ttcttagaac gctttatgcc ttctgttgcc ctctttgagc agggtagtaa
    34201 ggtgagctgg gatgactatt ttcctttgct ccgatatcaa attttgttaa atcccgacct
    34261 aaccaccgtc tatcaggtca atcaagaaat ggtagtacgc attaaggaag ccatcaagac
    34321 agcccagtct gtggaagaat tggtcgagtt agtgactacc aaacgttaca ccaaggcgcg
    34381 tgtcagacgc ctattgacct atattttgat gcaggctaga gaaaatgtct tgccagaagt
    34441 cattcatgtc cttggattta ctgaaaaagg taggcaacat ctcaagtctt tgaaaggtca
    34501 ggtcagtcta gtcagccgaa ttggcaaaga accttgggat gctatgaccc aaaaagcaga
    34561 ccagatttac caactaggaa atccaagtat agcagaccag aattttggaa gagtgccgat
    34621 tagaatagaa acaaactaag tctaccgaaa ggtaggcttt ttgagatttt ttacgaataa
    34681 tactcttcga aaatcaaatt caaatcgcgt caacgtcgcc ttgccgtact caagtacagc
    34741 ctgcggctag tttcctagtt tgctctttga ttttcattga gtataaatag atagaaaaga
    34801 aaatcttgta caagttcctg acaatttctt tcttttcgtg tataatagtg gaaaagagct
    34861 aaaacgaggt atggttatgg aagcagtcct ttactcaaca ttccgaaatc atttaaagga
    34921 ctacatgaag aaggtaaatg atgaatttga gcctttgacg gtggtcaata aaaatccaga
    34981 tgaggacatt gtagtccttt caaagagtga gtgggatagt atccaagaaa ccctgagaat
    35041 tgctcaaaat aaggaacttt ctgataaggt tttgcgagga atggctcaag ttcgtgctgg
    35101 aagtactcag gtccatgtta ttgaggagta agaaatgctg ctcaagttta cagaagatgc
    35161 ctgggcagat tattgctact ggcaaaatca ggataagaaa acgttaaaaa gaatcaataa
    35221 actaatcaag gatattcaac gtgatccctt tacaggaata ggtaaaccag aaccactcaa
    35281 atatgattac caaggagcct ggtcacggcg tattgatgca gaaaatcgct tgatttatat
    35341 gatggatgga gatagcgtgg ctttcttgtc ctttaaagat cattactaag tctattgaaa
    35401 ggtaggcttt ttctcaagtc tctactaaac tactatttct aaacaacaag tttattttgg
    35461 taaatgtgtt ccaaattccc caaaacatat tctattttag gtttgtgaaa atcacttttt
    35521 tatggtagaa tgtaaaagaa tgtatgtcat tcggaataac aataaaatga ggtaaaaaca
    35581 tggaaatcat gtcgcttgcg attgctgttt ttgccgtcat cattggttta gtcattggat
    35641 atgtcagcat ctcagctaag atgaaatcat ctcaggaagc tgcagagttg atgcttttaa
    35701 atgctgaaca agaagcaact aatttacgtg gacaagctga gcgtgaagcg gatttacttg
    35761 ttaatgaagc caaacgtgaa agcaagtctc ttaaaaaaga agcactattg gaggccaaag
    35821 aagaagccag aaaataccgt gaagaagtgg acgctgaatt caaatcagaa cgtcaagaac
    35881 tcaaacaaat cgaaagtcgt ttgacagaga gagctactag ccttgaccgt aaggacgaca
    35941 atttgacgag taaagaacaa acacttgaac aaaaagaaca aagtatttct gatagagcga
    36001 aaaaccttga tgcgcgtgaa gagcaattag aggaagtcga aagacaaaaa gaagcagaac
    36061 tagagcgtat tggtgctctg tctcaggcag aagcacgaga tattatcttg gctcagacag
    36121 aggaaaactt gaccagggag attgccagtc gcattcgcga agctgagcaa gaggtcaagg
    36181 aacgttctga caaaatggcc aaggacatct tggttcaagc tatgcaacgt atcgctggtg
    36241 aatatgtagc ggagtcaaca aactcaacag ttcatctgcc agacgatact atgaagggac
    36301 gcattattgg tcgtgaaggt cgtaacattc gtacctttga aagtttgaca ggggtcgatg
    36361 tgattatcga cgatacacca gaagtggtga ccttgtcagg atttgatccg attcgtcgtg
    36421 agattgcccg tatgactatg gaaatgttgc tcaaagatgg tcgtatacat ccagctcgta
    36481 tcgaagagtt ggttgagaaa aaccgtcaag agattgacaa taagattcgt gaatacggtg
    36541 aggctgctgc ctatgaaatt ggtgcgccaa accttcatcc agacttgatg aagattatgg
    36601 gacgtttgca gttccgtact tcatatggac aaaatgtttt gcgccattcg attgaggttg
    36661 ctaagttggc tggtatcatg gcgagcgaac ttggtgaaaa tgcggctctt gcccgtcgtg
    36721 ctggattcct tcacgatatc gggaaagcca ttgaccatga ggttgaaggt agccacgttg
    36781 aaatcggtat ggaattggcc cgtaagtaca aggaaccccc agttgtggtg aatacgattg
    36841 ctagtcacca cggagatgtt gaagctgaga gcgtgatagc agttatcgtc gctgcagcag
    36901 atgccttgag cgcagcccgt ccaggtgctc gtagtgagtc tcttgaaagc tacatcaagc
    36961 gtctccatga tttggaagaa attgctaacg gctttgaagg agtgcaaact agctttgccc
    37021 ttcaagcagg acgtgaaatt cgtatcatgg tcaatccagg aaaaatcaag gacgacaaag
    37081 tcacaatctt ggctcacaaa gttcgtaaga aaattgaaaa caatctcgat tatccaggaa
    37141 atatcaaggt aaccgtgatt cgcgagcttc gtgcagtaga ttatgctaaa taaataagaa
    37201 agagcagttg aaaaattact gcttttttgt tacactagat agaaagactg taaaggataa
    37261 tctggctttt tgccattatt ctagagaaat gttatttcac agattgacta aaaggagaca
    37321 caatggcaga ccgaggctta ctaatcgttt tttctggtcc ttcaggggtt ggaaaaggaa
    37381 cggttagaag agagattttt gagagttctg aaaaccaatt tcaatattct gtatcgatga
    37441 cgacacgcgc acaacgtcct ggagaagtgg acggtgttga ctatttcttc cgtactcgtg
    37501 aagaatttga agagctgatt cgtcaaggac agatgttgga atacgcagaa tatgtcggta
    37561 actactatgg aactcctctg acctatgtca atgaaacctt ggacaaggga atcgatgttt
    37621 tccttgaaat tgaagttcag ggtgctcttc aggtcaagaa aaaggttcca gatgctgtct
    37681 ttatcttcct gacaccacca gatttggatg aattgcaaga tcgcttggta ggtcgtggaa
    37741 cagatagtgc agaagtgatt gcccaacgaa tcgaaaaggc caaggaagaa attgccctca
    37801 tgcgtgagta tgattatgcg attgtcaacg atcaggtacc cctagctgct gaacgtgtca
    37861 aatgtgtgat tgaagcagaa cacttctgtg tggatcgtgt cattggtcac tatcaggaga
    37921 tgttaccaaa atctccaact acccgataaa atttagaaaa taggtacaag caaatgatgt
    37981 taaaaccctc tattgatacc ttgctcgaca aggttccttc aaaatattca ctcgtaatct
    38041 tggaagcaaa acgtgcccac gaattggaag caggtgcccc agcaactcaa ggtttcaagt
    38101 ctgaaaaatc aactcttcgc gctttagaag aaatcgaatc aggaaacgtt acaattcacc
    38161 cagatccaga aggaaaacgt gaagcagtgc gtcgccgtat cgaagaagaa aaacgccgca
    38221 aagaagaaga agaaaagaaa atcaaagagc aaattgctaa agaaaaagaa gatggtgaaa
    38281 aaatttaagg ttggggggac tcaatcttat tttttctatt gcaagaatgt actgacaagg
    38341 aggaggtgag aagatggccc tagctaagat tatcgtagat gtgcccttga tgcagacgga
    38401 ccagccctat agttacagga ttccggagga atttgaggga atgctggaag ttgggatgcg
    38461 ggttcatgtg ccttttggta agggtaatcg cctgattcaa gggattgttc ttggtttgga
    38521 gtcccaatca gatggagaag agatggagca agatttaaaa gatattgcag aggtgctgga
    38581 tttttctcct gttctcacgc cagaacaact ctggctggct gaggagttac gcaaatctgt
    38641 cttctcctac aaaatctcta tcctcaaggc catgcttccg ggatttctga attctagcta
    38701 tgacaagatt ctctatcctc tggaaggctt gagtcaggaa gaacgagtac gcctgtttga
    38761 ttcagaagat tcgctagcct tttcttctct ggatttaggt aagcaagctg aaatgatgcg
    38821 tttgactaga aaaggcctgc ttggtctgga atatcaggca gtcgatcaaa agaaggtcaa
    38881 gacccagtct tggtatgagg ttgaccatgc tcaattagaa ggtgttgaga tttctacacg
    38941 tgccaagaaa aagttggaac tgagagatta tctgctgtct catccagaga gcgcttcctt
    39001 ggctagcttg ttagagtcct actcgcgaga gcaagtcaac ttctttgtgg atcaaggtgc
    39061 tgttaccata gtccaaaagg aagttcgacg ctcggctgct tattttgaag gaattgaagc
    39121 aagtagacct ttggagttaa atccagaaca aagacaggcg cgtgatgcgg ttgtgagttc
    39181 tattggcagt tctcaacctc cctttctact tcaagggatt acaggaagtg ggaagaccga
    39241 ggtttacttg cagattatcc aaggtgccct ggataagggt aagacagcta ttttgctggt
    39301 acctgagatt tccttgactc ctcagatgac cgagcgtttt atagcacgtt ttggggacaa
    39361 ggtagccatt cttcactcag gattatccaa tggcgaaaag tatgatgaat ggcgcaaggt
    39421 ggagcgtggc gatgcccaag ttgttgttgg tgccagatct gctatctttg ctcctctgaa
    39481 aaatctgggt gtcatgatta ttgatgaaga gcatgaagcg gcttataagc aggacagcaa
    39541 tccccgttac catgccagag aggtagctat tttacgggct cagtataatc aagcaactct
    39601 ggtacttgga tctgcaacgc cgagcttaga gagccgggca cgtgctggca aaggcgtcta
    39661 tcaacactta cgtctaaccc aacgtgccaa tcctttggct acaatccctg aggttcaagt
    39721 gattgacttt cgagactata tcggacaaaa tgagacgtca aactttacgc ctcctttgct
    39781 agaggctatc caagaccgtc tggttaaaaa agagcaggtg gttctcatgc tcaatcgccg
    39841 tggttattct agctttgtca tgtgtcggga gtgtgggacg gtggatactt gtcccaactg
    39901 cgatatttct ctgaccttgc atatggatac caagactatg aactgccatt attgtggttt
    39961 ctcgaaggat attcctcagg tctgtcctaa ctgtaagagc cgcagtattc gttactatgg
    40021 gacgggaact cagaaggctt atgatgagct agcagaactc tttccccaag ctcgcattct
    40081 gaggatggat gtggatacga ctcgaaagaa aggcagtcac caagccttgc ttgaccagtt
    40141 tgggcgaggg gaagcggata ttttacttgg tactcagatg attgcaaagg gtttggattt
    40201 tcccaatgtt accctagtcg gagttctaaa tgcggatacg gccttgaatc tgcctgattt
    40261 ccgttcttct gagagaacct tccagctctt gactcaggtg gcaggtcgag caggtcgggc
    40321 tgaaaaagca ggtcaagtct tgatacagtc ctacaattcg cagcactatg ctattcgatt
    40381 tgctaaggat caagattacg aaggctttta tgcctatgaa atgggaatca gacgacaact
    40441 cggctatcca ccttactatt tcacgattgg tattaccctt tctcacaaga aagaagaaga
    40501 ggttttcaaa cgtgcctatg aagtcatgaa cattttgcgg tcaggcttgt cagagaccag
    40561 tcccattctg gggccaacgc caaaaccgat tgcccgtacc cacaacctct atcattacca
    40621 gattttaatt aaataccgtt tagaagatga gctggggccg accctcaacc aggtcttggc
    40681 cttgactcaa gaacgggaaa atagtgagct ccgtctcagc attgaccatg agccgcagca
    40741 atttttataa gaaggagaag atatgacaaa actaatcttt atggggaccc ccgacttttc
    40801 agcaacagtc ttaaaaggac ttttgacaga tgaccgttac gaaattctag ccgttgtgac
    40861 ccagccagac cgtgctgttg gtcgtaaaaa agttatccaa gaaaccccag tcaagcaggc
    40921 tgccaaggaa gcaggactat ctatctacca acctgaaaaa ttatctggaa gtccagagat
    40981 ggaagaactt atgaagctag gagcagatgg aattgtgact gctgcttttg ggcagtttct
    41041 cccaagcaaa ctccttgata gcatggactt tgctgtcaac gttcatgcct ccctccttcc
    41101 tagacaccgt ggtggtgcgc ctatccatta tgccttgatt caaggggatg aggaagctgg
    41161 tgtgaccatc atggaaatgg ttaaggaaat ggatgcagga gatatgattt ctcgtcgcag
    41221 cattccgatc acagatgagg acaatgttgg caccttgttt gaaaaattgg cgctagttgg
    41281 tcgtgatttg cttttggaca ctctgcctgc ctatattgct ggtgatatca aacctgaacc
    41341 gcaggatacg agtcaggtta ccttctctcc aaatataaag ccagaggaag aaaaactgga
    41401 ctggaacaaa accaatcgtc aactctttaa ccaaattcgt ggaatgaacc cctggcctgt
    41461 tgcccatgct ttccttaagg gcgaccgctt taagatttat gaagccctac cagtagaagg
    41521 tcagggaaat ccaggtgaga ttctctctat cggcaagaaa gaattgattg tcgcaacggc
    41581 tgaaggggct ctatccctca aacaagtgca gccagctggt aagcctaaga tggacattgc
    41641 ttccttcctc aacggagttg gacgtacatt gactgtagga gaacgatttg gtgactaaag
    41701 tagaaacggc tagaagttta gctctagcag tgctagagga tgtttttgtg aaccaagcat
    41761 actcaaatat cgccttaaat aagcatctaa aggggagtca acttttggca gcagacaagg
    41821 gcttagtgac cgagctggtc tatggaacgg tagcccgtaa actgactctg gaatggtacc
    41881 tatcccactt tatcgaagac agagaccagt tagacagctg gctctatgtc cttcttctca
    41941 tgagtgccta ccaactccgc tatttggaca agattccaga tcatgctgtg gtcaatgaag
    42001 cagtggaatt ggccaaactt cgtaaaaaag gcagtgaaaa attggtcaat gccctccttc
    42061 gccgtatctt gcgtgaaggc tggccagata ttgctagcat caagcgaaaa aacaagcgtg
    42121 actccattgc ctattctctc ccagtttggc tagttgccaa actcaaggaa gaatacggag
    42181 aggagagagc aaaagccatc tttgaaagcc tgttagtgcg aaacaaagcc agtattcgtg
    42241 taacagacct aagtcgaaaa gaggaaatcc aagccttgtt ggaggcgaat gattcccttt
    42301 tagcaaccac tggtctggtt aaggagcagg ggcattttgc agggcataat ttgtttgcgg
    42361 atggagccat taccatccaa gacgagtcca gtcagctggt tgctccgacg cttgatttac
    42421 aaggtgatga gcgagtgctt gatgcctgtg cggctccagg tgggaaaaca gcccatatag
    42481 cctcttatct tacgacaggt caggttactg ctctggactt gtacgaccac aagttggatt
    42541 taattcaaga aaatgcccaa cgtctgggag ttgaagatcg ggttcaaact caaaaattgg
    42601 atgccagaaa ggtgcatgag ttttttgacc aggattcctt tgataagatt ttggtggatg
    42661 ctccttgttc aggaatcggt cttttgcgcc gaaaaccaga tatcaaatac aataaagaaa
    42721 cggcagattt cgcgtccttg caggaaattc agttagaaat attaggtagt gtttgtcaaa
    42781 tactaggcaa aggtggtata ataacttata gcacctgcac tatcgtctca gaggagaatt
    42841 ttcaagtcgt taaggccttt ttagagagtc atcccgagtt cgagcaggta aaactagaac
    42901 atgaatgtaa ggatatcatg aaagacggct gtatcctcat tacacctgaa ttgtatggaa
    42961 gtgatggatt cttcatcagt caatttcgca agatatcgga ttaggaagga actgacacat
    43021 ggaaatttca ttattaacag atgttggtca gaaacgaaca aataaccaag actatgtcaa
    43081 ccactatgtc aatagagctg gacgtaccat gattatttta gctgatggga tgggaggtca
    43141 tcgcgcaggg aatatcgcta gtgaaatggc ggtcacagac ctgggtgtag cttgggttga
    43201 tacccagatc gatacagtca atgaagtgcg tgaatggttc gcccattacc tagaaattga
    43261 aaatcaaaag attcaccagc ttggtcagga tgaagcttac agaggcatgg gaactacttt
    43321 ggaagtcctt gctattattg ataatcaggc tatctatgct catattggtg attcgcgtat
    43381 cggcttgatt cgtggagaag aataccatca gttgacgagc gatcattcct tggttaatga
    43441 attgctcaag gctggtcaat tgacaccaga agaggcagaa gcttatccgc aaaaaaatat
    43501 tatcacccag tctattgggc aaaaagatga aattcagcct gattttggga cagttatcct
    43561 tgagtcaggt gactatctct tgctcaatag tgacggcttg accaacatga tttcaggcag
    43621 tgagattcgt gatattgtaa ccagtgatat tcctttagca gataaaacgg agacacttgt
    43681 tcgttttgct aacaatgcag gaggtttaga caacattacg gttgcccttg tttctatgaa
    43741 cgaggaggat gcagaatgat ccaaatcggc aagatttttg ccggacgcta tcggattgtc
    43801 aaacagattg gtcgaggagg catggcggat gtctacctag ccaaagactt aatcttagat
    43861 ggggaagaag tggcagtgaa ggttctgagg accaactacc agacggaccc gatagctgta
    43921 gctcgttttc agcgtgaagc gagagctatg gcagatctag accatcctca tatcgttcgg
    43981 ataacagata ttggcgagga agacggtcaa cagtatcttg caatggagta tgtggctgga
    44041 ctggacctca aacgctatat caaggaacat tatcctcttt ctaatgaaga agcagtccgt
    44101 atcatgggac aaattctctt ggctatgcgc ttggcccata ctcgaggaat tgttcacagg
    44161 gacttgaaac ctcaaaatat ccttttgaca ccagatggga ctgccaaggt cacagacttt
    44221 gggattgctg tagcctttgc agagacaagt ctgacccaga ctaactcgat gttgggctca
    44281 gttcattact tgtcaccaga gcaggcgcgt ggttctaagg cgactgtgca gagtgatatc
    44341 tatgccatgg ggattatttt ctatgagatg ttgacaggcc atatccctta tgacggggat
    44401 agcgcggtga ccattgccct ccagcatttc cagaaacccc tgccgtccgt tattgcagaa
    44461 aatccatctg tacctcaggc tttagaaaat gttattatca aggcaactgc taaaaagttg
    44521 accaatcgct accgatcggt ttcagagatg tatgtggact tgtctagtag cttgtcctac
    44581 aatcgtagaa atgaaagtaa gttaatcttt gatgaaacga gcaaggcaga taccaagacc
    44641 ttgccgaagg tttctcagag taccttgaca tctattccta aggttcaagc gcagacagaa
    44701 cacaaatcaa tcaaaaaccc aagccaggct gtgacagagg aaacttacca accacaagca
    44761 ccgaaaaaac atagatttaa gatgcgttac ctgattttgt tggccagcct tgtattggtg
    44821 gcagcttctc ttatttggat cttatccaga actcctgcaa ccattgccat tccggatgtg
    44881 gcaggtcaga cagttgcaga ggccaaggca acgctcaaaa aagccaattt tgagattggt
    44941 gaggagaaga cagaggctag tgaaaaggtg gaagaagggc ggattatccg tacagatcct
    45001 ggcgctggaa ctggtcgaaa agaaggaacg aaaatcaatc tggttgtctc atcaggcaaa
    45061 caatccttcc aaattagtaa ttatgtcggc cggaaatctt ctgatgttat cgcggaatta
    45121 aaagagaaaa aagttccaga taatttgatt aaaattgagg aagaagagtc caatgagagt
    45181 gaggctggaa cggtcctgaa gcaaagtcta ccagaaggta cgacctatga cttgagcaag
    45241 gcaactcaaa ttgttttgac agtagctaaa aaagctacga cgattcaatt agggaactat
    45301 attggacgga actctacaga agtaatctca gaactcaagc agaagaaggt tcctgagaat
    45361 ttgattaaga tagaggaaga agagtccagc gaaagcgaac caggaacgat tatgaaacaa
    45421 agtccaggtg ccggaacgac ttatgatgtg agtaaaccta ctcaaattgt cttgacagta
    45481 gctaaaaaag ttacaagtgt tgccatgccg agttacattg gttccagctt ggagtttact
    45541 aagaacaatt tgattcaaat tgttgggatt aaggaagcta atatagaagt tgtagaagtg
    45601 acgacagcgc ctgcaggtag tgtagaaggc atggttgttg aacaaagtcc tagagcaggt
    45661 gaaaaggtag acctaaataa gactagagtc aagatttcaa tctacaaacc taaaacaact
    45721 tcagctactc cttaaaagca gatggataat caaaatgagt aatcaatctt tgtcatgatt
    45781 tcatggcaaa gatttttttt gagtccggat ttgtgataga atagagggag ttgataaaag
    45841 gaggaaagca tggaagaatc aaaagaatta aatgccgtca ttgatgtgat tatgctagcg
    45901 gggactattc tccttaaaag tggctcagaa atccatcgtg tagaagatac catgattcga
    45961 atcgcgcatt cgcaggggat tgtggattgc aatgtccttg ccatgcctgc cgctatcttt
    46021 ttctctattg aaaataccaa tatttcgcgc atgaagcgcg tgacctcctc ttcttataac
    46081 atcgaaaaag tctgcgatgt gaaccagatt tctcgtcagc tagttggggg gcagattgac
    46141 ttagaaacag cctttaagca attgacggcc ttgcaagcca aaccccttcc ctatactaag
    46201 ttgcaggtaa ctctggctgc gacctttagt gctcctttct tttcagttat gtttagcgga
    46261 aatatctacg acgcacttgg ggcaggagtg gcgaccttat ttggttttgc cttttccctc
    46321 tatgtggaaa aatttatccg aattcccttt gtgacagcct ttgctggagc ctttgtcttt
    46381 gggataattg cccagttttg ggctcgctac acaggttttc cttcaacggc agatttgatt
    46441 atagctggtg cggtcatgcc gtttgtacca ggtattgcct tgaccaatgc ggtccgtgat
    46501 attatgacca accacataaa ctctggtatg agtaagatgt ttgaatccct gctcattacc
    46561 ctcgctttag gggcaggaac ttctgtcgcc ttggtattga tgaactaata tgacactaac
    46621 aaccttttta ttacaagcag tagcaagttt tcttgccatt atcacttttt taatcgtact
    46681 caatgtgcaa cggtctatgc tcttacctgg agggattttg ggcatgactg tctggctaat
    46741 ctatctcttg ctcaaggaac cgaccaatgt cattgtagct accttcattg cagccattat
    46801 tggttcttgt gtcagccaga ttttaagtat tctttataag acacctgctg tggtctttat
    46861 cttggccatt ttggcaccgc tggttccagg ttatctctcc taccgaacaa ctgccttttt
    46921 tgtgacaggg gactataata aagcactggc aagtgcgacc ttggttgtca tgttggcttt
    46981 ggtaatctct attggaatgg ctagcggaac agtgattctc agactctatc attatataaa
    47041 aacacatcga gtatcgtaga ctttacagaa ataaaagaat tttctgaaaa atgagataaa
    47101 taaattgata acgctttcta tatgtgcgag aataccgcac ttatgaagaa attgcggctg
    47161 attttggtat tcacgaaagc aacttaatcc gtcggagcca atgggttgaa gtaactcttg
    47221 ttcaaagtgg tgttacgatt tcaagaactc ctctcagctt tgaggacacg ataatgattg
    47281 atgtgacgga agtaaaaatc aatcgcccta aaaaacaatt agcgaattat tctggtaaaa
    47341 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
    47401 tggatatcgc tgtgaactat agtcatgata tgaagttgtt caaaatgagt tgcagaaata
    47461 tcggacaagc tggtaaaatc ttggctgaca gtgattatca agggctcatg aagatatatc
    47521 ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaacagct gaagataaag
    47581 cctgtaacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
    47641 aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
    47701 tgaatttgat tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
    47761 ctactttcct tattgtctgt aaatctactg accttgttgt ttatcccagt catggtttct
    47821 agttcgggct cagagtttca aagtggatgg caagagcatc aattgattgc tgagaaggtt
    47881 agtaaaacac ttgataagac atttgataag gatgtcagag aaattccgac cagtcagttt
    47941 tatcaaaaat ttgtagatga gatgggaagg acttactcag gaaatttgat cctccaggag
    48001 ctgataactg tgaatggagc ttataaagct acttatatcg gtgaactctc tagcaactaa
    48061 tcattcttta aaatgatgac caataagagg cttgatttgg tgaatcaagt cttttttctc
    48121 tcttttactg ccatttgtga taaaatagta tagaacgatt ttttacatga atgataaaac
    48181 agaggtaaat atgacaatcg gtattgataa gattggtttt gcgaccagtc aatatgtctt
    48241 gaaattacaa gacttagcag aagcgagggg aattgaccct gaaaaattaa gtaaaggact
    48301 cttactcaag gaattgagta ttgcgcccct aactgaggac attgtgacct tggcggccag
    48361 tgctagtgac tctattttaa ctgagcaaga aagacaagaa gttgacatgg tcattgtggc
    48421 taccgagtca ggaattgacc agagtaaggc tgcggccgtc tttgtgcatg gcttgctggg
    48481 catccagccc tttgctcgta gtttcgagat taaagaagcc tgttatggag cgactgctgc
    48541 ccttcattat gccaaattgc atgtggaaaa ttctccggag tccaaggtct tggtcattgc
    48601 cagtgatatt gccaaatacg gtattgaaac tccaggagaa ccaactcaag gtgctggaag
    48661 tgtagctatg ttgattacac aaaatccacg catgatggcc tttaataatg acaatgtagc
    48721 tcagacccgt gacatcatgg atttctggcg accaaattac tcgacaactc cttatgtaaa
    48781 tggtgtttat tctacccaac aatacttgga tagtttgaaa acgacttggc ttgaatatca
    48841 aaaacgctac cagcttactc tggatgattt tgcggctgtt tgtttccact tgccttatcc
    48901 taaattagcg ctaaaaggct tgaaaaaaat catggataag agcctgcctc aagagaaaaa
    48961 agacctctta caaaagcatt ttgaccagtc tattctctac agtcaaaagg tggggaatat
    49021 ctacacaggt tcacttttcc ttggactttt gtctctcttg gaaaatacag atagcttgaa
    49081 agctggggat aaaatcgccc tttatagtta cggaagtgga gctgtggctg agttcttcag
    49141 tggtgaattg gttgaaggat atgaagctta tttggataaa gaccgcttga acaagctcaa
    49201 ccaacgaact gccctatccg ttgcagacta tgaaaaggtc ttttttgagg aagtaaactt
    49261 ggatgaaaca aactctgccc agtttgctgg ctatgaaaat caagattttg ccttggttga
    49321 aattcttgac caccaacgcc gttatagcaa ggttgaaaaa taatgaagat aagttggaat
    49381 ggattttcta aaaaatcata ccaagagcgc ctcgagctgc taaaagctca ggcgctcctt
    49441 agtcctgaga gacaagctag tctggagaag gatgaacaga tgagtgtgac tgtggcagac
    49501 cagctgagtg agaatgtggt gggaactttt tctctgcctt attcgctggt tccggaggta
    49561 cttgtcaacg gtcaggaata caccgttccc tatgtgacag aagaaccctc tgtggttgcg
    49621 gcggccagct atgccagcaa aatcatcaag cgtgcaggtg gttttactgc acaagtccat
    49681 cagcgccaga tgattgggca ggtagccctt tatcaaattg ctaatcctaa actagcgcaa
    49741 gagaagattg ccagcaagaa agcggagctc ttggagcttg ccaatcaagc ctatccttct
    49801 atcgttaaac gtgggggtgg ggcgagtgac ctgcatgtcg agcagataaa aggtgaacca
    49861 gactttctcg ttgtttatat tcatgttgat acccaggaag ccatgggtgc caatatgctc
    49921 aacaccatgc tggaagcctt gaaaccagtc ttagaagaac tcagtcaggg acagagtctc
    49981 atgggaatcc tgtccaacta cgcgaccgat tctctggtga ctgcaagctg tcgcatggcc
    50041 tttcgctact tgagccgcca aaaggatcaa ggacgagaga ttgcggagaa aattgcattg
    50101 gctagtcagt ttgcgcaggc tgatccttac cgagctgcta ctcataataa aggaattttt
    50161 aatggtattg atgcgatttt gattgccact ggtaatgact ggcgtgccat cgaagctggg
    50221 gcccatgcct ttgccagtcg agatggacgc tatcaaggtc ttagctgctg gacgctggac
    50281 cttgaaagag aagaattggt cggtgagatg accctgccca tgcctgtagc gactaagggt
    50341 ggctctatcg gcctcaaccc acgtgtagct ctcagtcatg atctactagg aaatccttct
    50401 gccagagaat tagcccagat tatcgtgtcc atcggtcttg ctcaaaattt tgcagccctc
    50461 aaagccttgg taagtacggg catccagcaa ggtcacatga aactacaggc caaatcccta
    50521 gctctcctag ctggggctag tgaatctgaa gttgctcccc tagtagagcg cctcatctca
    50581 gataaaacct ttaacctaga gacagcccag cgctatctcg aaaatttaag atcataaaaa
    50641 ctcagacgaa tcggtctgag ttttcttgtg tttaaatact ttttcctggt aatagtgtaa
    50701 ctggtaagaa gtaaccagtt gtggcgactt ccttgccttc aatcttttgc aagagaagat
    50761 caatagtgag acaagcaatc tcttccaaag gttgcttgat agtagccaat tgagggtagt
    50821 aattttcgat aaagtaggtc ccatcatagc cgatgacctt gagctctttt gggacagaaa
    50881 tgcccaattc ttgagcgatt ttaatgacca gaatagctgt caaatcatcc gaagcaaaaa
    50941 tggcatctgg tttttcccgg gtcaagatat tcttgatttc catttctttt ctgacgggag
    51001 aaaagtcact ggaaacattg ataataggag cttttgggag tacggatgca aaaccagcgt
    51061 ggcgcagtcc ggttggcgaa ttagaattgt cattccctgt aatcatgatg atagactggg
    51121 cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc agcatagttg tcagaggaga
    51181 caacagggat gtctggcgat aggtttcggt caaaggaaat aatcggcgct gtcacacgat
    51241 tgtagtcttc gattcctagg ttgtgactac cagaaatgat gccgtctacc tgattggctt
    51301 ccaacatttc gatgtattcg cgttccttct cagaatcatg ttcactgttg cagatgatgg
    51361 tcttgtaacc atttttgaag agttggtgtt ccaatttatc aatcaattct gcatagaaaa
    51421 cattggaaat attggggaaa atcaagccga ttaacttagc tgattttcct tgcagactac
    51481 gagccaggtt gttgggttta tagcccaatt ctctcatggc ttcattgact ttttggatgg
    51541 ttttctcaga tagataccct tttttattga taacccgaga aacggtagta ggactgacgc
    51601 ctgcaagttt ggcgacatca gttagttttg tgaccataat ctaattcata gtaaattcca
    51661 gttgggtttc cagatttgat caggatacca ttttggtccg catgtgggaa gacacgacca
    51721 gaaaatactt tttctccttt attgatgaaa atttcaaaga cagagttatc gatgaagatt
    51781 gtagcagtag tagcctgatt ctcgataggg caagaacgag ttgtcccaaa ttcttgggca
    51841 tactgttctc cagcctggct acgatccact gtcacttgac cgtttacaag gtcaaagttg
    51901 attgaaagtc ccttaccttc tttatcagca agtaagacaa tctcgctctg gctattagct
    51961 tccaagttga gttcaagttc gtaagtgttc ttggtttggg aacggtttga gaaggcttct
    52021 tcagaagcac gaaggtcctt aatagcagcg actggatact ggtagagctt gtcgtctttg
    52081 atagtgagtt ccttgaccaa agagaaggtt ccttggtggt caaaacggtc agatgggtaa
    52141 gaaacatctg gcaaaccaag ccagctaact gctagagcac gcccatcagg agcgttgaag
    52201 gcttgagttg cataggcttc gaaaccgtaa tccatgtttt gaagttgaga cacatctacc
    52261 attttggcat ttttagggtc aaaggaagcc ccaatcttat acatatttgg aaagatatta
    52321 tcgtagtcta gaactttctt atccaatcct tgtggacagt agagaaggac aggatgttcc
    52381 tctacaaaga ccagattagg acattccatc atgtaggcag tacggtcgtt agcaaagtca
    52441 aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga cagccttgta gagacggacg
    52501 aagccttttt tctccaagtc ctgtccaccg acgacagcat agtattgacc tttaaagtta
    52561 aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg gctggtcaat caagatcttg
    52621 tcaatctttg taatcttacc ctccttgtcc atcaaagcac cgatctggta tgggtgacgg
    52681 atccagtttt catcgcgaac atttcctgta taaaatagga ataagttatc gccaaattgc
    52741 atggcagaac cagagtaggc accgtggcta tctaatggag tatctggtaa aactttgatt
    52801 ccagtttctt taaagtgaac caaatcatca ctttctagct gtgcccaaga tttcaaaccg
    52861 tgggctgcac caaaaggaaa attctggtaa aagaggatcc acttgccatc aaagtaagaa
    52921 aagccatttg ggtcgttgag aagtcctgtt tttggctcaa catggtaatg agtatgccat
    52981 ggagattgtg ccatattttc ctttatatgt tgaatttctt cttgcgtcca atcttgataa
    53041 agtctgtaac gacgctcagt tgtccattcc attcattcct ccaaaaatct tatcactttt
    53101 aatagtaact gttttcgata aaaaatgcaa gccttttata ttaaaaaaga gaaaaaactg
    53161 tcaaacgatt atcataaaat aaatacagga aatcaatcaa atttttacga aaatgtgaaa
    53221 gataatgaaa taaaagactt tttaaccaag gtttcaaact tatttttcaa gaaattcctg
    53281 atgaaacagt caaaaacaat caatctaaag cttgcccact aagtagatag aatatttttt
    53341 ctgcaaaacg cttgacatat ttttaaaaca tgataaaata atagtcgtaa gggcgaataa
    53401 aatcgctttc aaacaagaac aaaatgttat ataaggagat ttttgcaaat gaacaatcag
    53461 gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg aaaatgtcaa tagtgttgcc
    53521 cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag agaaaatcaa taaagaagtg
    53581 attgagaact tggaaaaagt tcaaggtgct ttctttaact cagggcaata ccaaattatc
    53641 tttggtacag gtacagttaa caaaatgtac gatgaagttg ttgtacttgg cttaccaaca
    53701 tcatctaagg atgacatgaa agcagaagtt gctaaacaag ggaactggtt ccaacgtgct
    53761 atccgtactt tcggtgatgt tttcgttcca atcatcccag ttatcgtagc gacaggtctc
    53821 ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc cacttccagg tgactttgca
    53881 acttacacac aaatcttgac agatacagcc ttcatcatct tgccaggttt ggttgtgtgg
    53941 tcaaccttcc gtgtatttgg tggaaatcct gccgttggta tcgttcttgg tatgatgctt
    54001 gtctctggct cacttccaaa cgcttgggca gttgctcaag gtggtgaagt aacagcgatg
    54061 aacttctttg gtttcatccc tgttgttggt ttgcaaggtt ctgttcttcc agccttcatc
    54121 atcggggttg tcggagctaa atttgaaaaa gctgtccgca aggttgttcc agatgtcatt
    54181 gacctcttgg taacaccatt cgtgacactt ttggtcatgt ctatccttgg actctttgtc
    54241 attggaccag ttttccacgt tgttgaaaac tacatcctta ttgctacaaa agcgattctt
    54301 agcatgccat ttggtcttgg tggtttcttg attggtgggg ttcaccaatt gatcgtcgtg
    54361 tcaggtgtgc accacatctt caacttgctt gaagtgcaat tacttgctgc tgaccatgct
    54421 aacccattca acgctatcat cacagctgct atgacagctc aaggtgctgc tactgttgcg
    54481 gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg ctttcccggc tgctctttct
    54541 gccttcctag gtattacaga gcctgctatc ttcggggtga acttgcgctt ccgtaaacca
    54601 ttcttccttt cattgattgc tggtgcaatc ggtggtggat tggcttctat ccttggactt
    54661 gctggtactg gtaatggtat caccatcatc cctggtacaa tgctttatgt gggtaacgga
    54721 caacttccac aataccttct tatggtagct gtatcatttg cccttggttt tgctcttact
    54781 tacatgtttg gttacgaaga tgaagtagac gcaactgcag ctgcaaaaca agctgaagtg
    54841 gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa atgaaacact tgtaactcct
    54901 atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc cagtcttctc aagtggagct
    54961 atgggacaag gtatcgctgt gaaaccaagc caaggcgtgg tctatgcacc agctgatgct
    55021 gaagtttcaa ttgcctttcc aacagggcac gcttttggtt tgaaaacaag aaatggtgct
    55081 gaagttttga ttcacgttgg tattgacact gtatctatga acggtgacgg ttttgaagca
    55141 aaagtttctc aaggtaataa ggtgaaagct ggcgatgttc tgggaaaatt tgactcaaac
    55201 aaaatcgctg cagctggact tgatgataca acaatggtta tcgttacaaa tacaggtgac
    55261 tacgcttcag tagctccagt cgcaacaggt tcagtttcga agggggatgc tgtgatcgaa
    55321 gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca aatgacatgt ttgttcgttt
    55381 ttattagata gtaagattta cagaggaaaa tctaaaaaat agagacattt agactttcga
    55441 agtatgctat aataaagaaa ataaaaacaa gaggtttatc atgacaaaat tatatggaag
    55501 cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt gatgaaaact ttaacgttgt
    55561 agaaaaaaca caatttccaa caacaactcc aatcgaaaca atcgataaaa ccattgagtt
    55621 cttctcaaaa ttcgataacc ttgctggtct tgcagttggt tcatttgggc cgattgatat
    55681 tgacaaaaac tcaaaaactt atggctttat cacgacgact ccaaaaccaa actgggcaaa
    55741 tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg ccaatgtact tcacaacaga
    55801 cgtaaacagc tctgcttacg gtgaagtggt tgcccgtaac aatgctggtg gtcgtatcga
    55861 aaacttggtt tactacacaa tcggtacagg tatcggtgca ggtgtcatcc aacgtggtga
    55921 gtttatcggt ggtgtgggtc accctgaaat gggtcattat tatgttgtta gacacccaat
    55981 ggatattgaa aaagagttta agggtgtttg tcctttccat aagggatgtc tggaaggcta
    56041 tgcagctggt ccaagtttgg aagctcgtac aggtgtacgt ggggaaaata ttgaactcaa
    56101 caaccctgtt tgggatgttc aagcctacta tatcgctcaa gctgcggtta atgcgacagt
    56161 gactttccgc ccagacgtga ttgtctttgg tggaggggtc atggctcaac aacatatgct
    56221 ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt tacctaccag taccagatgt
    56281 gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt tctgccacac ttgggaactt
    56341 tgttcttgca aaagaagttt caaaataaag cacaaaatcc gcttgggaaa ccaaacggat
    56401 tttgtggttg aaaacaatat ttttgagcct ttccttaagt gattacggac ggtagcgact
    56461 ttcttcgaaa ttccatacct aaactttgag acactaggct caaagtttcc gaatacctga
    56521 aaccattaga tttcaggtgt ttctatcacg gcgggaaggc taggtaagtc ctcgcctcac
    56581 tatcgaaaaa tatgcatgat ttccatacca aagtatattt agtatcaagc tatagttaat
    56641 ctacgcttta aaaatccact tgggaaacca aacggatttt ttacgtgtca aagcatttgc
    56701 cagaaaaagt caataatata ggtcagaccg taggtataaa ccacgagggt aaagggtttg
    56761 gtcagaatga tgatggtcat gtagcgcttg aaactcatct tggtcagggc agccagcata
    56821 cagagaaagt cagctgggct aatgggccaa atcatcataa aaataaagaa gcggtcaaaa
    56881 cgattgccct tatctagcca gccgatgtac ttgtcgtagg tgcgcttgct gacgacagac
    56941 tggacaaagg cagctccgta taggcgcact agataaaaga taatggcaca gccaatcacg
    57001 atgccgatat agttgtagat agtcccgatg atgtgcccgt agataaagac cccagccacc
    57061 gaggtcaagg cccctggaat gatagggacg acagtctgta aaatctgtaa aaagataaag
    57121 agaggtggac cccagatgcc tgcctgctgg ataaaggcag agagggtttc cttggattgt
    57181 aaaatcccag cctgataagc ccaaatacag aaaatcaaac tcccaacccc accgacaatc
    57241 gatgagatat tgataactcg ctgcagaagg ggagaaacag ctttcatttg tttatcctgt
    57301 gacatgtaaa ctcctcatag atagtatatt tctactatac catattttgg aggagaaagg
    57361 gggaatgagt cttttttgat aaggaataga aagtaaatag cccttcgaga cttagaatag
    57421 gtctgtcaac taaaggttat atgcattcta ggtttcgaat aatcgcaatt ccataaattt
    57481 aaaagcattc taagtttcga atagcttatc tgagataatt ttgaggcatt cgcgctttcg
    57541 aatagtcatt ttccctaaag tttagatgta ttctgaagct agaaagacta aaatctaaaa
    57601 gtagtaagag tctctctctg atggacgtaa tttatggcta gtatgaatcc tttgaattgt
    57661 tagttaattt taatattaat cagttctgaa ataattacta aatatagtta gatggtgaat
    57721 taattattgc taaatttcaa gttcaagtta gtcatccaga agtcttctct gggggacttg
    57781 tagttcaagc attttttagg atagttgtta atccactttt cgatgaatgc gacttccttt
    57841 gtagtcgttt tcttagttcc ctgaggtaac catctatgaa tgaacttgtt gtgattttta
    57901 ttagatccta tagtggtgtg cataatagat ataatagatt gaaactagaa tagtacgcat
    57961 ctacttctaa aacattgtta gaaatcgatt tgactgtccc gatctatttg tcctgttttt
    58021 atttcatttt actatataat ccttagaaaa catatcggac aagcggttga attccgttcc
    58081 gtccattagt agataaagga ttactccttc ttgaaatgac agatgaactt gtttcttata
    58141 aaaatgttgt ctgaaactat tcgctttttt ccagaagttt tagaggaaga aaactttatg
    58201 aggaaaaagg agttactcaa ataacaattc aggattaaaa atagacagtt gaggagcgga
    58261 aggtataaat taagtttgct actgtataat ggatttatca ctaatactct tcgaaaatct
    58321 cttcaaacca cgtcagcttc gccttgccgt agatatagtt actgacttcg tcagttctat
    58381 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tttatctgca acctcaaagc
    58441 tgtactttga gcagcctacg gctagcttcc tagtttgctc tttgcttttc attgagtata
    58501 aaagtgctcc aggccatatt ttacacagca atagtcttct aaaaatggac aaaaacattg
    58561 taaaggctat caaaaaggag tataatgagt gcaagaaatt tcggaggtga aagatgctag
    58621 aagtaagaag tctagagaaa agttttggat ccaagcaagt tttgtttggt attgactttc
    58681 aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga
    58741 ttttccatag tattttaaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg
    58801 atattcgtca ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc
    58861 ctaaattgac agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca
    58921 aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctga
    58981 cagataaaat caagagtctg tcaaaaggaa atcagcagaa gattcagctc attattactc
    59041 tgattcatga accagacctg attatcttgg atgagccttt tagtggattg gacccagtta
    59101 atacagaatt gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct
    59161 tttctgacca tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag
    59221 atggccgtgt ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacgc
    59281 gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac
    59341 aggtgagctt gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa
    59401 gggaactctt cccaatcttg actcaagatc aatatatcgc aacatttgac caacaagcgc
    59461 caactatcga tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt
    59521 tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat
    59581 ttcgccgttc ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat
    59641 ggctaaaaat aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa
    59701 gaatgtaaat ggtgttaact tcgactataa agatgaagca agtgccaaag aagcaattaa
    59761 agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt
    59821 ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa
    59881 tgaactgcaa aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg
    59941 cttagcgcag acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt
    60001 tattcaaaca attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta
    60061 tgcgggtgta acggctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt
    60121 tttttctagc ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt
    60181 gattttaacg catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa
    60241 agatttgcca ttcttggctc agtctggtat tttggatcac ttgggagatg ctatctcact
    60301 gaataccttg ctctttattt tgatcagtct tttcatgtat gtagtcttgg cagccttcct
    60361 aggatctatg gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt
    60421 gattatgggt ggtttttttg gagtgacagc tctaggtgca gctggtgaca atctcctctt
    60481 gaagattggt tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa
    60541 tggctatgcg gggggagcag aagcatggat ttcacttgct attacagtga tttttgcggt
    60601 ggtagcaaca ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt
    60661 agggatttgg aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc
    60721 gaggttttta aaggtgaaaa gggtggaatc acgaacctaa ttatgtacac attatgtaaa
    60781 caggttgctt gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt
    60841 ctaaaacatt cttataaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca
    60901 ttttgcgata tagtgaaagg aaataagtca gctcacaaaa aacgcataat atcaaggatt
    60961 ttttgaactg ccccccaaaa gttagatttt ttctgtctaa cttttggggg cagttcatat
    61021 tcaacacttg atactatgcg ttttctaatt ttaaagactt tttgcctggt ctcttttgtt
    61081 ctatgagtat gttacatatc taggtaaaaa ttatttaaag caaattaacc ttatttctca
    61141 agatgtagta ggttccgaga taaaagatag ctatgaatat gagttcttta acaatggcta
    61201 tacctgctcc catatagaaa tggtcattga gtcctaccag tgaattgaca tagaaattag
    61261 aactaagatt gaagaaaagt tcaataaatc caatgacgat ttggatacca atgtaggctg
    61321 caacagcgag tgctgtacgg tattcattga aaagctgtcc aatggaaata gccaggtaga
    61381 tgcagaggat tcctgaaatg gtatttagta ggaaggatat acctgtaaga aagatctgag
    61441 ggagatgtgt ttctacaaat gtaatcacat aagaaagagg aatccattct ggagctgtta
    61501 aagccagaat aataacagca cttagagcca atacagcggt gctaatcaat gaccagataa
    61561 aggcaccgat tagtttggct gtgatgatat ggtgttcaga aactggcaag gtcaaagtca
    61621 gatagccttg tcggtcgtag acactacctt tgaagcgttt aataatcaag aaaatggttg
    61681 aaatcgcaag tgtaagcatc aagccaccaa agactgtagc tagaaaaagt agcatagtag
    61741 cctgactttc ttggtaaggt agatttttaa agccttgtgt ctgtattccg atgagggcag
    61801 aaaggactag cacggctgcg tagagggcta aataccactt gttaacattt ttaaattcgt
    61861 agtgaactaa attccaaaac ataaataatc tcctttgctt aggccttaaa ttcctgacgg
    61921 aagagttggt caatggattc acctgactcg tagcgaatat catctacatt tccttgacgg
    61981 acgacttttc cgtcttttag gaagacaatt tcatccaaga ttggctcgat atcagaaatc
    62041 aagtgggtag aaatcaaaac ggtagaagtt ggtgagtagt tgttgataat ggtattgagg
    62101 atataagcac gggctgctgg atccacccca ccaatgggtt catccaaaac atagagacga
    62161 gcatcacggc tcataaccaa aatcagttga accttttctt tgtttccttt tgatagtttc
    62221 ttgagacgac tattttcatc aatgcccagg tctgcaagta gatgatgagc gcgttcaaga
    62281 ttgaaatctt tatagaaggt cttgaagtag gttagggctt ctttgacctt catttgctca
    62341 ttgagatagg tcgtatcagg caaataagct acaacggcct tggttgctgg gcttgggtcc
    62401 atgtcgttga tgaggacacg tccttgatct ggttgtaaga ggccattaat tagtttaatc
    62461 agggttgttt ttcctgagcc gtttggccca agaaggccga caatttttcc agctggaatg
    62521 tcaagagaaa cattttcaag ggctggtgtt gctccatatg atttggatac attttcaaat
    62581 actagtaatg acataggctt aaactccttt aatataatca ctgactacgc ctggtagttc
    62641 ttctttttca tagccaaaat ggatcatgga ggaaacgaag tgttccaatt cttcttctga
    62701 taattgtttg cgtgactgag cgattagctc cttatcctta gtcacaaatc gtccagttgt
    62761 tcgcttgctg tagacaaatc cttctcgttc aaggtctgat aaggctcttt ggatggtatt
    62821 gggattgaca ccagcctcgc tagctagctc cctcacggtt ggaagttgtt gattgggttc
    62881 cagtgtatgg gaaacaatct gaagcttgat tttctccata atctgtaaat agatggtttt
    62941 tttgttgtca aatgtccagg acatcttagt ctcctttctc ttatcctttt gtcttaacta
    63001 aataatacaa caaaacaaaa aacttgtcaa gcaaaaagaa gaattgtttt gggaatcgct
    63061 taaaaaatgg tataatgaaa agaaaacgat aaggagggaa aggatgcgtt gtccaaaatg
    63121 tggggctacc aagtcaagtg ttatcgatag tcgccaagca gaagaaggga acaccattcg
    63181 tagaagacgt gagtgcgacg aatgccaaca ccgttttaca acctacgaac gagtagaaga
    63241 aagaacctta gtggttgtta aaaaagatgg cacacgggaa caattctcca gagataaaat
    63301 ctttaatggg attatccgct cagcccagaa acgtcctgtg tcaagtgatg aaatcaacat
    63361 ggtagtcaat cgtatcgaac agaaactccg tggtcgaaat gaaaatgaaa ttcaaagtga
    63421 ggacattggt tcactcgtca tggaggagtt ggctgaattg gacgagatta cctatgtacg
    63481 ttttgctagt gtctatcgta gttttaagga tgtcagtgag ttagagagct tgctccaaca
    63541 aatcacccag tcctctaaaa agaaaaagga aagataaatg aagccaattg accgtttttc
    63601 ttatctaaag aataatcggg tgtcgcaaga tacctcatct ctggtacagt gctacctccc
    63661 gattatcggt caggaggcac tgagccttta tctttatacg attagttttt gggataatgg
    63721 tagaaaggaa tatctttttt caagtatcct caatcatctc aactttggga tggatagact
    63781 gataaaatca ttgaaaatct tatctgcttt taatctcttg actctctatc aaaaggggga
    63841 tgtttatcag ctagccctcc atgctcctct atctagtcaa gacttcttgg ggcatcctgt
    63901 ttatcgcaga ctcttagaga aaaagattgg cgatgtagct gtggaggatt tgaaagttga
    63961 aagtgctgat ggtgaagaaa tacctgtctc actcaatcaa gtctttccag acttggcaga
    64021 actaggcagt caagaagacc ttggtctcaa gaagaaagtg gccaacgatt ttgacttgga
    64081 ccattttcgt cagcttatgg ctcgagatgg acttcgcttt gcggatgagc agtccgatgt
    64141 cttaaacctc tttgctattg ccgaggagaa gaaatggact tggtttgaaa cctatcaatt
    64201 ggccaagtca acagctgttt ctcagattat ttcaaccaaa cgcatgcgtg aaaaaattgc
    64261 tcaaaaacca gtttcctctg actttagtct taaggaagcg accattatca aagaagccaa
    64321 aagtaaaact gccctgcagt tcttggcaga aatcaagcaa acacgcaagg gaaccattac
    64381 ccaaacagaa agagaactct tgcaacagat ggctggcttg ggcttgctgg acgaagtcat
    64441 caatatcatt cttttattga cctttaataa ggtcgattcg gcaaatatca atgagaaata
    64501 tgccatgaag gtagccaatg actatgccta tcaaaagatt cattcggcag aaaaggcagt
    64561 cttgcgcatc cgtgagcgag gacagaaagc aaaaacacaa aaacagaatc agactgcccc
    64621 agtaaaaacc aatgttccta aatggagtaa tcctgaatat aagaatgaaa ccagcgagga
    64681 aactcgtctg gaactagaac gtaagaagca agaactatta gctcgattag aaaaaggagg
    64741 agattagatg gaaagtgtcg gagacgtact caaacgtcaa cccagccgtt tttattatca
    64801 agatttggtc cagaaaatca tgaaggaccc tgatgttgcg gcttttatcc agcaagaatc
    64861 cttgactcca gaggaattaa atcgcagtat ctccaagttt aatcagtaca tcaccgagcg
    64921 tgacaagttt ctccgtgggg atacggatta tattgccaaa ggctacaagc cgattttggt
    64981 taagaatcat ggctatgcag atgtttcata tgaagaaact cctgagctaa tcgcggctga
    65041 aaaagaagcg gctattaaga accgtctcaa gttaatcaat ctaccagcca gtctcaagaa
    65101 agctagtttg gctcaagttg acttggatga tttggggcgc ttaccagttt ttgaaaagct
    65161 actagccttc gtggagcaat atccagctat tcgaaaaggt ctttacttat atggagactt
    65221 tggtgtgggt aaaagtttca tggtggcggc cttagctcat gatttatcag aaaaacgtgg
    65281 tgtttcatca actctcctcc actatcctag ctttgtcatt gatgtcaaaa atgctatcgg
    65341 tgatggcaat gttaagacct tagtggatga gattaagctt tctgaagtcc tgattttaga
    65401 tgatattggt gccgagcaat ccaccgcttg ggtgcgtgac gaaatcctgc aggtcattct
    65461 ccaatatcgg atgcaggaaa atttaccgac ctttttcaca tccaacttca actttgaaga
    65521 tttggagaag cattttgcga aagtgaaaca tggaaatgac gaaacctggg aagccagacg
    65581 ggtcatggaa cgcatccgtt atttggctga ggagactcgt ttagaaggag taaaccgtcg
    65641 atgacagaaa ccattaaatt gatgaaggct catacttcag tgcgcaggtt taaagagcaa
    65701 gaaattcccc aagtagactt aaatgagatt ttgacagcag cccagatggc atcatcttgg
    65761 aagaatttcc aatcctactc tgtgattgtg gtacgaagtc aagagaagaa agatgccttg
    65821 tatgaattgg tacctcaaga agccattcgc cagtctgctg ttttccttct ctttgtcgga
    65881 gatttgaacc gagcagaaaa gggagcccga cttcataccg acaccttcca accccaaggt
    65941 gtggaaggtc tcttgattag ttcggtcgat gcagctcttg ctggacaaaa cgccttgttg
    66001 gcagctgaaa gcttgggcta tggtggtgtg attatcggtt tggttcgata caagtctgaa
    66061 gaagtggcag agctctttaa cctacctgac tacacctatt ctgtctttgg gatggcactg
    66121 ggtgtgccaa atcaacatca tgatatgaaa ccgagactgc cactagagaa tgttgtcttt
    66181 gaggaagaat accaagaaca gtcaactgag gcaatccaag cttatgaccg tgttcaggct
    66241 gactatgctg gggcgcgtgc gaccacaagc tggagtcagc gcctagcaga acagtttggt
    66301 caagctgaac caagctcaac tagaaaaaat cttgaacaga agaaattatt gtagaaagtg
    66361 agaaattatg gccctaccaa ctattgccat tgtaggacgt cccaatgttg ggaaatcaac
    66421 cctatttaat cggatcgctg gtgagcgaat ctccattgta gaagatgtcg aaggagtgac
    66481 acgtgaccgt atttatgcaa cgggtgagtg gctcaatcgt tcttttagca tgattgatac
    66541 aggaggaatt gatgatgtcg atgctccttt catggaacaa atcaagcacc aggcagaaat
    66601 tgccatggaa gaagcagatg ttatcgtctt tgtcgtgtcc ggtaaggaag gaattaccga
    66661 tgcagacgaa tacgtagccc gtaagcttta taagacccac aaaccagtta tcctcgcagt
    66721 taacaaggtg gacaaccctg agatgcgaaa tgatatctat gatttctatg ccctcggttt
    66781 gggtgaacca ctgcctatct catctgtcca tggtatcggt acaggggatg tactagatgc
    66841 gattgtggaa aaccttccaa atgaatatga agaagaaaat ccagatgtca ttaagtttag
    66901 cctgattggt cgtccaaacg ttggaaaatc aagcttgatc aatgctatct tgggcgaaga
    66961 ccgtgttatt gctagtcctg ttgctggaac aactcgtgat gccattgata cccactttac
    67021 agatacagat ggtcaagagt ttaccatgat tgatacggct ggtatgcgta agtctggtaa
    67081 ggtttatgaa aatactgaga aatactctgt tatgcgtgcc atgcgtgcta ttgaccgttc
    67141 agatgtggtc ttgatggtca tcaatgcgga agaaggcatt cgtgagtacg acaagcgtat
    67201 cgcaggattt gcccatgaag ctggtaaagg gatgattatc gtggtcaaca agtgggatac
    67261 gcttgaaaaa gataaccaca ctatgaaaaa ctgggaagaa gatatccgtg agcagttcca
    67321 atacctgcct tacgcaccga ttatctttgt atcagcttta accaagcaac gtctccacaa
    67381 acttcctgag atgattaagc aaatcagcga aagtcaaaat acacgtattc catcagctgt
    67441 cttgaacgat gtcatcatgg ataccattgc catcaaccca acaccgacag acaaaggaaa
    67501 acgtctcaag attttctatg cgacccaagt ggcaaccaaa ccaccaacct ttgtcatctt
    67561 tgtcaatgaa gaagaactca tgcacttttc ttacctgcgt ttcttggaaa atcaaatccg
    67621 caaggccttt gtttttgagg gaacaccgat tcatctcatc gcaagaaaac gcaaataaaa
    67681 aagtagaatc tggaatgaca gttccggatt tttttgatat aataaaataa tagaaaacgc
    67741 tatcaaaaga aggagggtga tgtcggtgat ggaacatttg tttaaattct tacttttagc
    67801 accgtacttt tattttgata actggattga gaaggccaac agaaatagta agttttttcc
    67861 aattttttat tatttttact ggttttacat ccccttctat tctcttttta gccttgcttg
    67921 gacagttgtt tcagttctgt ttttcaatac cgtcttgaga aatgtgacag atatcaagtt
    67981 atggggcatt tggtttcttt ttattctgct agctattggt atgaattggt taacttattc
    68041 ctgtttcaaa gaaatgtttc gcttgagaca ggaactaggg aagtctaagg gtggaaggca
    68101 ttgatttata tcggtttcta tttgtaggag gtggcttatg gtacctctaa aatcatttat
    68161 tacacgctat tccaaggttt atattggtaa taacatttaa tagaacgaaa ctaaagaaaa
    68221 caatttaaaa aaggaggctt gtgatggaac acttgtttaa aatgataatc ttattaccct
    68281 gtttttactt tttcagctgg attgacaagg ataatagaga aagtaaattt ttcccaattt
    68341 tttactattt ttactggatt tacatcaccc tctatgctct ttttagcctt gcttggacag
    68401 ttttttcagt tctgtttttc aatatcgtct tgagaaattt gacagatatc aagttatggg
    68461 gtatttggct attattacta cttatcgctt ttgctagtga ctggttagac tatatctgtt
    68521 tcaaaaaaat gcttgacttg agacgggaac tagggaaatc taaaggtgtg cataaaggaa
    68581 ggtgtaggaa ctaaaaaatg actgtatcta tgatttgttt atggagctat agatacagtc
    68641 atttttattt tgattatgaa acttgagaga aatattcatc ttgtatagtg gattgaatat
    68701 ggaataatac aatacaactt ataaaacatt ggtataaaat gctttagatc ccctaattga
    68761 ttcgttcaca ttctattaca ttctattaca atctactata ataaaatgat gagagttatt
    68821 acaaattata ggtttgaaaa atcattaatt tctttttcga gtattttaac taatgcctct
    68881 tctttggtta gtcgtaataa agttattcct ttatcaatca aatcggagtt atgttgtagt
    68941 attcccaagc gtacttgaga gaatccaaga atatcgtata tttttaattc ttctgctaat
    69001 accaaaagtt gtagggtgat tgtttcacat tctttgaata aatgatgttg aaaatataca
    69061 gtggagagat tggctaaaaa agatgataaa aatgcttttg tttctcggaa gtatttatat
    69121 ttctcgatgg ttttcataat tctatcaata agaaggggaa gattttcaga aggaaagaaa
    69181 aagagaatgg ttccaagcaa tttcaaatca ctaatgtacc atgtatccat aggttcaaga
    69241 tagtcccaaa tttcttcata caaatctttc aagacgtggt tgtttttgaa tcctttagtt
    69301 cgtaactctg tgacaatttt tgtatgacga tagatatttt gaataggaac atcgtgatgt
    69361 gtcttaagat atttttgaca tttctcagtg agttcaacca tttttctagt atcttgaaaa
    69421 gtagacggat tttggctctc tacaataata tctcgccttt tactaggatg gtattcgttg
    69481 catatatact tgaattctgc caagctcata tcaatttgtt caagaagaaa taccatgttt
    69541 tcaaaactgg gaataacttt accgtgttca atatttgtta gagttgttcg atgtatgact
    69601 tgtccacata catcttgttg ggtcaatcct tttgactttc gaatttcttt aaaaatttgt
    69661 ccataatccc atctcatatt gttcctccta ggtaaatgtg aatattttct acatttataa
    69721 aaaacgtaga aaaaggtggt attattatat caaaaaggag ggaaaaagtc atgggcttta
    69781 aaaaatattt gaagaattta ccgaaaaact ctggattttt gatttggagt tggattcaac
    69841 ttatctggtt tgaaacatgg ttttggggat aaagaaatta gagtctatac ataataagta
    69901 aaggaggaat ttgtatgata taccatcgtt tagaataagt ctatatttaa aatagaagtt
    69961 ataaggaatc ttcttgaata aaaaatgaaa ggaaacagaa aaaatgaaaa ttaagaaatt
    70021 attgaaaatg gttattcctg ttttaatgat aagtgctgtt ggaactactt tcgtagaagc
    70081 aaatcagata ggtgctttta gtaattttgt tattactacc agttataaga gaacaggtta
    70141 tttgactaaa gaaaatgaag gtgcggaata tatcatgaac ttaaatcctt gtagaaattt
    70201 acatcccatg actgttaagc atcgtatagt aaattctaat ggagaagctc gtagtggaga
    70261 atcgttaaca acctgtggta ctcgttcaac tcatggtaat tgggcaacgg ttggctatgt
    70321 ttatgcagca gatatggcaa gacaaaattg gtgggattta tcagctgcca tttcaggtag
    70381 ttggtcacca aattaattcg taaagtaggt ataatttatg aagattcctc tcttaacttt
    70441 tgcaaggcat aaatttgttt atgtcttgct tactttgctt tttcttgctt tggtttatcg
    70501 tgatgttttg atgacttatt tcttttttga tattcatgcg cccgatctag ctaaattcga
    70561 tggacaagca attaaaaatg acttattaaa atcagcatta gattttcgta ttctccagtt
    70621 caatctaggt ttttatcaat catttattat tccaatcatc attgttttgc taggttttca
    70681 atatattgag ctgaaaaata aagttttacg attgagtatt ggaagagaag tgagttatca
    70741 agggttaaaa agaaagttga ctttgcaagt tgcaagtatc ccttgtttga tatatttagt
    70801 gactgtgctg ataattgcaa ttataaccta tttctttggg actttttctc ctcttggatg
    70861 gaattctcta ttttctgatg gaagtggttt acaaagactc ctagatggag agataaaaag
    70921 ctatttgttc tttacttgtg tcctactaat cggtattttc atcaatgcaa tctatttttt
    70981 acaaatagtt gattatgtgg ggaatgtgac tcgttcggca atcacctatt tgatgtttct
    71041 ttggcttggt tctatgctgc tctatagtgc cttgccttac tatatggttc ctatgacgag
    71101 tttgatgcaa gctagctatg gggatgtaag tttgatgaaa ctctttactc cttatatcct
    71161 ttatattgtc ccttatatgg tgcttgaaaa atatgaagat aatgtttaag aattttaaca
    71221 atatttggct aaagagaaag atcgttttac tacttcgtat agttctgatg atgattttga
    71281 taaactatct attgtcaaca gcggttcaaa agcaggatgc tgttatcttt ttcaagagag
    71341 aattgatttc aatcttttcc tataatgact attctgaagc gaatttagaa atccccaaac
    71401 tcttgttaaa cctttcgctt ttcatggtag gatggctctc tgtcatttta cttgaaagtg
    71461 atttggcaga ccattaccat cacttgattc gctatcaatc aagctccttt ttcgattata
    71521 caaggaaacg attggttgtc atttctaaat tttttactca agatttactt gtctggttcc
    71581 ttggtttact tccgctagga attcatttca aaacagtcgc acttttcttt ttacttgctc
    71641 agttaatgat tttgtactta ctactgtctt atctgatagc actgattagt gcgggcgctg
    71701 gtttttcctt ttttctctat tttttagcat ttgtgggaca agaatggatg atggatcata
    71761 ttgtaacagt gtatttacta ctcttaagct tattagttat gttgattgtt agtcgcttgg
    71821 aagagaaatt taagaaagga taaacgatga gacttgaaat tataaatgga cagaaaattt
    71881 atgggaaaag acctatttta aatcagttga atttggtgtt tcaatcagga aaaatttatg
    71941 gacttaaagg tgataatgga tctggcaaga cggttctttt aaagatactt gctggttata
    72001 ttaagcttga caaaggaaaa gttcttcaag acgggaaagt ctacgggata aaaaatcatt
    72061 atattcagga tgcaggaatt ttaattgaaa aagtcgagtt tttatctcat ttatccctga
    72121 gagaaaattt ggaactgtta aggtattttt catctaaagt tacggaaaaa agaattgcct
    72181 attggattca atactatgat ttacaggaat ttgaagacat tgaataccgt catttatcct
    72241 taggaacaaa gcaaaaaatg gccttgattc aagcctttat ttcctctcct tctatactct
    72301 ttctcgatga acctatgaat gctttggatg agaagagtgt gaggttaacc aaacaggtca
    72361 ttttatctta cctgaaaaaa gaaaatggtc tggttatcct gacatcgcac atatcggaag
    72421 atatttcaga cctttgtaca gatgtattag ttgtcgaaaa tggacatata caaatgtaaa
    72481 ggatatacaa tcctaggaga tggcttatgg cacatctaaa atcatttatt acacgctatt
    72541 ccaaggttta tattggttta gttctgctga tctggctgtc tttcttcttt atcccttggg
    72601 atagagcgat tctgggggta aggattgaca tcttcatcat acagaaaatc ttgctagctt
    72661 ttggaattct gtccattctc atggccttgc tgtccaagaa agtcagtctc tttgtttttg
    72721 gactgatttg ctgtctttct ctttggatta acttatttat cacatttgcc attttgccga
    72781 tttttggcaa ttaaacagtc ataaaagtcg gagaggttag cttgaaaact aacctctttt
    72841 tccttttcaa aatggggatt cttccttgaa aataatcagt aattgtgcta aaattaaagg
    72901 aacattctaa aatattcgga atttaaagta aggaaaaaca tggctaatat tttaaaaaca
    72961 attatcgaaa atgataaagg agaaatccgt cgtctggaaa agatggctga caaggttttc
    73021 aaatacgaag accaaatggc tgctttgact gacgaccaac taaaagcaaa aacagttgaa
    73081 tttaaggaac gttatcaaaa tggagaatca ctggattcat tgctttacga agcatttgcg
    73141 gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc cttataaggt tcaggtcatg
    73201 ggggggattg ttcttcacca tggtgacgtg ccagagatgc gtacagggga agggaaaacc
    73261 ttgactgcga ccatgccggt atacctcaat gccctttcag gtaaaggggt tcacgtagtt
    73321 acggttaatg aatacctgtc agaacgtgac gcgactgaga tgggtgaatt gtactcttgg
    73381 cttggtttgt cagtagggat taacttggct accaaatctc caatggagaa aaaagaagcc
    73441 tatgagtgtg atattactta ctcaactaac tcagaaatcg gatttgacta ccttcgtgac
    73501 aacatggtcg ttcgcgccga aaacatggta caacgtccgc ttaactatgc cttggtcgat
    73561 gaggttgact ctatcttgat tgacgaggct cgtacacctt tgattgtatc aggtgccaat
    73621 gcggttgaaa ccagtcagtt gtatcacatg gcagaccact atgtaaaatc tttgaacaaa
    73681 gatgactaca tcatcgatgt gcagtctaag actattggtt tgtctgattc agggattgac
    73741 agggctgaaa gctacttcaa acttgaaaac ctctatgaca tcgaaaacgt ggctttgact
    73801 cactttatcg ataacgccct tcgtgccaac tacatcatgc ttctcgatat tgactatgtg
    73861 gtgagcgaag agcaagaaat cttgattgtc gaccaattta caggtcgtac catggaaggt
    73921 cgtcgttatt ctgatggatt gcaccaagct attgaagcca aagaaggtgt gccaatccag
    73981 gatgaaacca agacatctgc ctcaatcacg taccaaaacc tcttccgtat gtacaagaaa
    74041 ttgtctggta tgacgggtac aggtaagact gaggaagaag aattccgtga aatctacaac
    74101 attcgtgtta ttccaatccc aacaaaccgt cctgttcaac gtattgacca ctcagacctt
    74161 ctttatgcaa gtatcgaatc taagtttaaa gcggttgtcg aagacgttaa ggctcgttac
    74221 caaaagggtc aacctgtctt ggttggtaca gtagcggttg aaactagtga ctacatttct
    74281 aagaaattgg ttgcagctgg tgttcctcac gaagtcttga atgccaaaaa ccactataga
    74341 gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg ttaccatcgc aaccaacatg
    74401 gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc gtgaacttgg aggactttgt
    74461 gttattggta cagaacgtca tgaaagtcgt cgtatcgata accagcttcg tggacgttca
    74521 ggtcgtcaag gagatccagg tgagtcacaa ttctacctat ctcttgaaga tgatttgatg
    74581 aaacgttttg gttctgaacg cttgaaggga atctttgaac gcttgaacat gtctgaagag
    74641 gccattgagt ctcgcatgtt gacgcgtcag gttgaagcag ctcagaaacg tgtcgaagga
    74701 aataactacg atacccgtaa acaagtcctt caatacgatg atgtcatgcg tgaacaacgt
    74761 gagattatct atgctcaacg ttacgatgtc atcactgcag atcgtgactt ggcacctgaa
    74821 attcagtcta tgatcaaacg cacgattgaa cgtgtcgttg atggtcatgc gcgtgccaaa
    74881 caagatgaaa aactagaggc aattttgaac tttgctaagt acaacttgct tcctgaagat
    74941 tctattacga tggaagactt gtcaggcttg tctgataagg ccatcaagga agagcttttc
    75001 caacgttcct tgaaggttta cgatagtcag gtttcaaaac tacgcgatga agaagcagtt
    75061 aaagaattcc aaaaagtttt gattctacga gtggtggata acaagtggac agatcatatc
    75121 gatgcccttg atcaattgcg taacgcggtt ggacttcgtg gctatgctca gaacaaccct
    75181 gttgttgagt atcaggcaga aggtttccgt atgtttaatg atatgattgg ttcgattgag
    75241 tttgatgtga cacgcttgat gatgaaagca caaattcatg aacaagaaag accacaggca
    75301 gaacgtcata tcagtacaac agcgactcgc aatatcgctg ctcaccaagc aagtatgcca
    75361 gaagatttgg atttgagcca gattggacgc aatgaacttt gcccatgtgg ttctggtaag
    75421 aaatttaaaa actgtcacgg taaaagacaa taaaatgaga tagtttagag gcggatatct
    75481 tgtgaaaagt aaatttttac tgggtatccg tttgctttat aaggagatga gttatggtat
    75541 ttacagcaaa aagctctaaa ataaatatag aagaagttcg tgccttgtca aaattagaag
    75601 gtcaggcttt ggagaggaaa tcacagagag atcaagagct agaagccatt atacgtggag
    75661 aagaccagcg aattctcttg gtaatcgggc catgctcatc tgataacgaa gaagctgtcc
    75721 ttgaatacgc taagcgtttg gcagtcctac aagaagaagt ggcagatcgt atctttatgg
    75781 ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga tggctataaa ggcttgattc
    75841 accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg aatcaaagcc gttcgccatc
    75901 ttcactatcg tgtcatcaca gaaacaggga tgacaactgc tgatgaaatg ctttatcctg
    75961 aaaaccttcc gcttgtagat gatttgattt cttacatggc agttggtgcc cgttcagttg
    76021 aagaccagca acaccgcttt gtggcaagtg gggcaggatt ttctactggt tttaaaaatc
    76081 caacctctgg aaatctcaat gtcatgttta atgggattta tgctgctcaa aacaaacaaa
    76141 gtttcctttt cttaggaaaa gaagtagaaa caactgggaa cccgctttca cacgctattc
    76201 ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa ctactattat gacaatttaa
    76261 ttgataccat tgcccagtat gagaaaatgg gcttggaaaa tccttttatc atcattgata
    76321 ccaatcatga caattctggt aagcagtata ttgaacagat ccgaattgtc cgccagacct
    76381 tgattaaccg tgcttggaat gaaaaaatta agcagttcgt tcgtggtttt atgattgagt
    76441 cttatctaga agatggtcga caaaatgagc cagaagtatt tggtaagtct atcacagacc
    76501 cttgcctggg ttgggataac acagaagctc ttgtcagaga aatttacaaa acgttaggag
    76561 aataagatgg catttattga aaaaggtcaa gaaatcgata tggaagtcat caaggctgaa
    76621 acccaattgt ctgcggaagc cttgagactc aaggaaagcc gtgacaggga attggcagat
    76681 attatttcag gggaagatga ccgtattctc ttggtgattg gtccttgctc ttctgataat
    76741 gaagaggcgg tcttggaata tgctcgccgt ttatccgcct tgcaaaagaa ggtagcggac
    76801 aagattttca tggtcatgcg cgtgtatact gctaagcctc gtaccaatgg agacggctat
    76861 aaaggattgg ttcaccagcc agatacttct aaggctccaa gcctgattaa cggcttgcag
    76921 gctgtgcgcc agttgcacta ccgcgtgatt acagagactg gtttgacaac ggcagatgag
    76981 atgctttatc cgtcaaatct gatcttggtg gatgacttgg tcagctacca tgccgttgga
    77041 gctcgttctg tggaagacca agagcaccgc tttgtggctt ctgggattga tgcaccagta
    77101 gggatgaaaa atccaacctc aggaaatttg ggtgttatgt ttaacgccat ctatgctgct
    77161 caaaacaagc aaaccttcct ttatcatggg caggaagttg agacatcagg taatcctttg
    77221 gcccatgtta tcctccgtgg agcagtcaac gagtatggca attatatgcc gaattactac
    77281 tatgaaaacc tactccaagc cattgaacgc tatgaaacca tgggacttga aaatcctttt
    77341 atcctcattg acaccaacca tgataactca ggcaagcaat atatggagca gattcgaatt
    77401 gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa ttaaaaagac ggttcgagga
    77461 tttatgattg aatcttacct agcagatggt cgtcaaaacc aaccagagat ctttggttgc
    77521 tctattactg acccttgcct aggttgggaa aatacagagg ccttggtaga agagatttat
    77581 gttaccttga caaaataagt gaaaaggatg gagttgggga atctcaactc cttttgatga
    77641 gaatgatagt tggacacgga attgacatcg aagaattggc ttcgatagaa agcgcagtta
    77701 cacgacatga aggatttgct aagcgtgtac tgaccgctca ggaaatggag cgcttcacca
    77761 gtctcaaagg acgcaggcaa atagaatatt tagctggtcg ctggtcggct aaggaggcct
    77821 tttccaaggc tatgggaacg ggcattagca agctcggttt tcaggatttg gaagtcttga
    77881 acaatgaacg tggggcgcct tattttagtc aggcaccatt ttcaggaaag atttggctgt
    77941 ctatcagcca caccgatcag tttgtgacag ccagtgtcat tttggaggaa aatcatgaaa
    78001 gctagtccac atagaccaac caaggctctg attcatctgg gagctattcg acaaaatatt
    78061 cagcaaatgg gggctcatat ccctcaagga acgctcaagt tggctgtggt caaggccaat
    78121 gcttatggtc atggagctgt tgccgttgcc aaggcaattc aagatgatgt tgatggcttt
    78181 tgcgtttcca atatcgatga agccattgaa ctcagacaag ctggactcag caagccaatc
    78241 ctcattttag gagtttctga aatcgaagct gttgctctag ctaaagaata tgacttcacc
    78301 ttgacagtgg ctggactgga gtggattcaa gcactcttag ataaggaagt ggacctaact
    78361 ggattgacag tccacctcaa gattgattca gggatgggac ggattggttt tatagaggca
    78421 agtgaggttg agcaggctca agatttgctc caacaacacg gtgttcgtgt tgaaggaatc
    78481 tttacccact ttgctactgc tgatgaggaa tcagatgact attttaatgc ccagttagaa
    78541 cggtttaaaa ctattttagc tagtatgaag gaagttccag agctggttca tgctagcaat
    78601 tctgcaacga ctctttggca tgtagagact attttcaatg cggttcgtat gggagatgcc
    78661 atgtatggtc tcaatccaag tggagcggtc ttggatttgc cttatgattt gataccggcc
    78721 ttgaccttgg agtctgctct ggttcatgtc aagacagttc cagctggagc ttgcatgggc
    78781 tatggagcaa cttatcaagc ggatagcgag caagtcatcg cgaccgtgcc aatcgggtat
    78841 gcagatggat ggacaagaga catgcaaaat ttctctgtct tggtagatgg ccaagcttgc
    78901 ccaattgttg gcagggtttc gatggaccaa atcactattc gattgcctaa gctttatccg
    78961 ctaggaacca aggtaacctt gattggctcc aatggggata aggaaatcac tgcaactcag
    79021 gtagcgacct accgcgtaac cattaactat gaggtggttt gcctcctcag cgaccgtatt
    79081 ccgagagaat attattagaa aagaaaggag tggagcatga atctacatca acccttgcat
    79141 gtcttgcctg gtgtgggacc aaagtcagca gaaaaatacg ccaaactagg aattgaaaac
    79201 ttgcaagatc tcttgctcta ctttcctttc cgttatgaag acttcaaaac caagcaggtg
    79261 ctggagctgg aagacggtga gaaggcagtt ctttctggtc aggtagtgac tcctgctagt
    79321 gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta gtctcaagca gggagaggtc
    79381 gtttttgcgg tgaatttctt taaccagccc tatctggctg ataaaataga gttgggagca
    79441 acccttgctg tctttggaaa atgggaccgc gctaaggcta gtctgactgg gatgaaggtt
    79501 ctggctcagg tagaagatga cctccagcct gtttatcgtc tggctcaggg aatcagtcag
    79561 gccagtctgg ttaaggtcat caagacggct tttgatcagg gactggacct cttaatagaa
    79621 gaaaatctgc cccagtcttt actagacaaa tacaaactca tgtcccgttg tcaggcagtc
    79681 cgagctatgc attttccaaa ggatttggca gaatacaagc aggctcttcg ccgtataaag
    79741 tttgaggaac tcttttattt ccaaatgcag ctgcagacgc tcaagtctga aaatagaatt
    79801 cagggaagtg gtctggttct ggattggtct caggaaaaag tgacagcagt taaagcaagt
    79861 cttccttttg ccctgaccca agctcaggaa aagagtttgc aggaaatttt aactgatatg
    79921 aagtccgacc accacatgaa tcgtctccta caaggggatg tggggagtgg aaaaacggta
    79981 gtcgctggct tggccatgtt tgcggcagtg acagcaggtt atcaggctgc cctaatggta
    80041 ccaacagaaa tcctcgcaga gcaacacttt gagagtttac agaacctttt tcccaatttg
    80101 aaactggctc tcttgacagg ttccttgaaa gctgcagaaa agagagaagt cttggagacc
    80161 attgccaagg gtgaggctga tttgattata ggaactcacg ctctgataca agatggggtg
    80221 gagtatgctc gtcttggttt gattattatc gatgagcagc accgttttgg tgtagggcaa
    80281 aggcgtattt tacgggaaaa aggtgacaat ccagatgtcc tcatgatgac ggcgactccc
    80341 attccacgga cgcttgccat cacagccttt ggagatatgg atgtttccat tatcgaccag
    80401 atgccagcag gtcggaagcc tattgtgacg cgctggatca aacatgagca actacctcag
    80461 gtcttgactt ggttagaggg ggaaattcaa aaaggttccc aagcctatgt catctctcct
    80521 ttgattgaag aatcagaagc tctagatttg aaaaatgcca ttgccttatc agaagagctg
    80581 acggctcatt ttgcaggcaa ggcagaggtg gctcttctac atggtaggat gaagagtgac
    80641 gaaaaagacc agatcatgca ggatttcaag gagagaaaga cggatattct ggtttcgacg
    80701 acggttattg aggttggggt caacgttccc aatgcgactg tcatgattat catggatgcc
    80761 gatcgcttcg ggctcagcca gcttcaccag cttagaggtc gtgtcggtcg gggggacaag
    80821 cagtcctacg ctgttctcgt tgccaatccc aagacggatt ctgggaaaga ccgcatgcgc
    80881 atcatgacag aaacgaccaa tggatttgtc cttgcggagg aagatttgaa aatgcgtggt
    80941 tctggtgaga tttttggaac cagacagtca ggacttccag agttccaagt ggctgatatt
    81001 atcgaagatt ttccgatttt agaagaagca agaaaggttg ctagctacat tagttctata
    81061 gaagcttggc aagaagatcc agagtggcgc atgcttgccc ttcatctgga aaagaaagaa
    81121 catctggatt aagctttctc taaggaaaac ttaagctagt ttttaggttt ggctcttata
    81181 ctaaagtcat caaaaagaaa cgaggactct catatgacag taacgattaa agtaaattac
    81241 caaaccactt tccaaaagaa ggaagcaaaa aactagtata aacagaagag agagcgaaat
    81301 gctctttttc gtttctaaaa ctactttcag cccatcatcc taaaagtaaa gaatctaaat
    81361 tcactttcta tttacccttc tttcttgcat tgattacata gatatgctac agttgtggta
    81421 acgattacaa aataaaagga gcatgctatg aaaaatccag ctttgctaga agaaattaag
    81481 acctatagag gaagggatga ggttccggaa gactttgatg ctttctggga tggggaagtg
    81541 aaaaatgttt ccacgcttcc atcctaccac ttggaggaaa gagatttcca cattcctcaa
    81601 gtcaagtgct atgagttaac atttgaagga agcaaggaag gaaaggtcta tgcacgcatt
    81661 gttcttccaa agagtgagga gaaggttcca ttaatcttcc attttcatgg ttatatggga
    81721 cgtggctggg actgggccga catgctgggc ttcaccgtag ctggttacgg tgttgtttcc
    81781 atggatgtgc ggggccagtc aggttactca caagacggct tgcgttctcc tttaggaaat
    81841 accgtgaagg ggcatattat ccgtggtgct gtggaaggtc gggaccacct cttttataag
    81901 gatgtttatc tggatattta ccagttggtc gaaattgttg ctagtctgtc tcaggttgat
    81961 gagaagcgtc tttctagcta tggtgcctca caaggagggg ctctagctct agttgcagca
    82021 gcgctcaatc ctcgaattca gaaaacagtt gccatttatc ccttcttgtc agacttcaga
    82081 cgggtgattg agattggtaa tactagcgag gcttacgacg aacttttccg ttatttcaag
    82141 tttcacgacc ccttccatga aacagaggag gaaatcatgg cgacccttgc ctatatcgat
    82201 gtcaaaaatc ttgcccatcg tatccaaggt gaggttaaga tgattacggg cttggacgac
    82261 gatgtttgct atcccattac ccagtttgcg atttataatc gtctgacctg cgataaaacc
    82321 tatcgtatca tgcctgagta tgctcacgaa gccatgaatg tatttgttaa tgaccacgtc
    82381 tacaactggc tctgtggaag tgagattcct tttaaatatc taaaataagg agtcgactct
    82441 aagcataaaa tcttaaaaat tacaaacacg catagtatca ggggattaag aaaacttgat
    82501 actatgcgtt ttatcatgga aatatagtaa aatgaaataa gaacaggaca aatcgatcag
    82561 gacagtcaaa tcgatttcta acaatgtttt agaagtagat gtgtactatt ctagtttcaa
    82621 tctattatat ttatagaatt ttttgttgct agatttgtca aattgcttaa aataattttt
    82681 ttcagaaagc aaaagccgat acctatcgag tagggtagtt cttgctatcg tcaggcttgt
    82741 ctgtaggtgt taatactttt caaaaatctc tttaaaccac gtcagc
//
LOCUS       DAVLTG010000002        80869 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLTG010000002 DAVLTG010000000
VERSION     DAVLTG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.002"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(60..263)
                     /locus_tag="VYN12_000091"
     CDS             complement(60..263)
                     /locus_tag="VYN12_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414549.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(256..1338)
                     /locus_tag="VYN12_000092"
     CDS             complement(256..1338)
                     /locus_tag="VYN12_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1414550.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1464..2246)
                     /locus_tag="VYN12_000093"
     CDS             complement(1464..2246)
                     /locus_tag="VYN12_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1414551.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2246..3589)
                     /locus_tag="VYN12_000094"
     CDS             complement(2246..3589)
                     /locus_tag="VYN12_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1414552.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3688..5004)
                     /locus_tag="VYN12_000095"
     CDS             complement(3688..5004)
                     /locus_tag="VYN12_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1414553.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5197..6423
                     /locus_tag="VYN12_000096"
     CDS             5197..6423
                     /locus_tag="VYN12_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1414554.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6622..8196
                     /locus_tag="VYN12_000097"
     CDS             6622..8196
                     /locus_tag="VYN12_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1414555.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8461..9249
                     /gene="codY"
                     /locus_tag="VYN12_000098"
     CDS             8461..9249
                     /gene="codY"
                     /locus_tag="VYN12_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1414556.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9249..9824
                     /locus_tag="VYN12_000099"
     CDS             9249..9824
                     /locus_tag="VYN12_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1414557.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGNLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            9906..9991
                     /locus_tag="VYN12_000100"
     tRNA            9906..9991
                     /locus_tag="VYN12_000100"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9940..9942,aa:Leu,seq:aag)
     gene            10274..11404
                     /gene="ugpC"
                     /locus_tag="VYN12_000101"
     CDS             10274..11404
                     /gene="ugpC"
                     /locus_tag="VYN12_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1414558.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11527..11697)
                     /locus_tag="VYN12_000102"
     CDS             complement(11527..11697)
                     /locus_tag="VYN12_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414559.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            11905..12663
                     /locus_tag="VYN12_000103"
     CDS             11905..12663
                     /locus_tag="VYN12_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1414560.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12750..13262
                     /locus_tag="VYN12_000104"
     CDS             12750..13262
                     /locus_tag="VYN12_000104"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1414561.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13444..14388
                     /locus_tag="VYN12_000105"
     CDS             13444..14388
                     /locus_tag="VYN12_000105"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1414562.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFLEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14397..15074
                     /locus_tag="VYN12_000106"
     CDS             14397..15074
                     /locus_tag="VYN12_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1414563.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLIQVSADFRN
                     AMDLWKD"
     gene            15172..15930
                     /locus_tag="VYN12_000107"
     CDS             15172..15930
                     /locus_tag="VYN12_000107"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1414564.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            15968..17473
                     /gene="lytC"
                     /locus_tag="VYN12_000108"
     CDS             15968..17473
                     /gene="lytC"
                     /locus_tag="VYN12_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1414565.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGTRYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            17969..18487
                     /locus_tag="VYN12_000109"
     CDS             17969..18487
                     /locus_tag="VYN12_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1414566.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18617..19123
                     /locus_tag="VYN12_000110"
     CDS             18617..19123
                     /locus_tag="VYN12_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1414567.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19123..19293
                     /locus_tag="VYN12_000111"
     CDS             19123..19293
                     /locus_tag="VYN12_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414568.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19325..20557
                     /gene="clpX"
                     /locus_tag="VYN12_000112"
     CDS             19325..20557
                     /gene="clpX"
                     /locus_tag="VYN12_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1414569.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRMGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20566..21153
                     /locus_tag="VYN12_000113"
     CDS             20566..21153
                     /locus_tag="VYN12_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1414570.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21164..21544
                     /locus_tag="VYN12_000114"
     CDS             21164..21544
                     /locus_tag="VYN12_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1414571.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21596..22486
                     /gene="rapZ"
                     /locus_tag="VYN12_000115"
     CDS             21596..22486
                     /gene="rapZ"
                     /locus_tag="VYN12_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1414572.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22483..23460
                     /locus_tag="VYN12_000116"
     CDS             22483..23460
                     /locus_tag="VYN12_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1414573.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSGMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23457..24368
                     /gene="whiA"
                     /locus_tag="VYN12_000117"
     CDS             23457..24368
                     /gene="whiA"
                     /locus_tag="VYN12_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1414574.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24402..25367)
                     /locus_tag="VYN12_000118"
     CDS             complement(24402..25367)
                     /locus_tag="VYN12_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1414575.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25503..26360
                     /locus_tag="VYN12_000119"
     CDS             25503..26360
                     /locus_tag="VYN12_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1414576.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26347..27126
                     /locus_tag="VYN12_000120"
     CDS             26347..27126
                     /locus_tag="VYN12_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1414577.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27150..28502
                     /locus_tag="VYN12_000121"
     CDS             27150..28502
                     /locus_tag="VYN12_000121"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1414578.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
                     "
     gene            28576..28950
                     /locus_tag="VYN12_000122"
     CDS             28576..28950
                     /locus_tag="VYN12_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1414579.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            28952..29800
                     /locus_tag="VYN12_000123"
     CDS             28952..29800
                     /locus_tag="VYN12_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1414580.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30066..30833
                     /locus_tag="VYN12_000124"
     CDS             30066..30833
                     /locus_tag="VYN12_000124"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1414581.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            30845..32029
                     /locus_tag="VYN12_000125"
     CDS             30845..32029
                     /locus_tag="VYN12_000125"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1414582.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32026..33897
                     /locus_tag="VYN12_000126"
     CDS             32026..33897
                     /locus_tag="VYN12_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1414583.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKSDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLNKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMSRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34040..35224)
                     /gene="mntE"
                     /locus_tag="VYN12_000127"
                     /pseudo
     CDS             complement(34040..35224)
                     /gene="mntE"
                     /locus_tag="VYN12_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
     gene            35528..38224
                     /locus_tag="VYN12_000128"
     CDS             35528..38224
                     /locus_tag="VYN12_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1414584.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAMDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFASDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38237..39028
                     /gene="yghU"
                     /locus_tag="VYN12_000129"
                     /pseudo
     CDS             38237..39028
                     /gene="yghU"
                     /locus_tag="VYN12_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
     gene            39144..39554
                     /locus_tag="VYN12_000130"
     CDS             39144..39554
                     /locus_tag="VYN12_000130"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1414585.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39566..41161
                     /locus_tag="VYN12_000131"
     CDS             39566..41161
                     /locus_tag="VYN12_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414586.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41328..41492
                     /locus_tag="VYN12_000132"
     CDS             41328..41492
                     /locus_tag="VYN12_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1414587.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41571..42299
                     /gene="yaaA"
                     /locus_tag="VYN12_000133"
     CDS             41571..42299
                     /gene="yaaA"
                     /locus_tag="VYN12_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1414588.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42577..43125)
                     /locus_tag="VYN12_000134"
     CDS             complement(42577..43125)
                     /locus_tag="VYN12_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1414589.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAARESVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43446..43934
                     /locus_tag="VYN12_000135"
     CDS             43446..43934
                     /locus_tag="VYN12_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1414590.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            43931..45118
                     /locus_tag="VYN12_000136"
     CDS             43931..45118
                     /locus_tag="VYN12_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1414591.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     CTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45111..45335
                     /locus_tag="VYN12_000137"
     CDS             45111..45335
                     /locus_tag="VYN12_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1414592.1"
                     /translation="MIDHFEIKVKDLQISGGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            45492..46838
                     /gene="asnS"
                     /locus_tag="VYN12_000138"
     CDS             45492..46838
                     /gene="asnS"
                     /locus_tag="VYN12_000138"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1414593.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            46991..47281
                     /locus_tag="VYN12_000139"
     CDS             46991..47281
                     /locus_tag="VYN12_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1414594.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47293..47763
                     /gene="ssbA"
                     /locus_tag="VYN12_000140"
     CDS             47293..47763
                     /gene="ssbA"
                     /locus_tag="VYN12_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1414595.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            47795..48034
                     /locus_tag="VYN12_000141"
     CDS             47795..48034
                     /locus_tag="VYN12_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1414596.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48329..49729
                     /locus_tag="VYN12_000142"
     CDS             48329..49729
                     /locus_tag="VYN12_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1414597.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            49731..50090
                     /locus_tag="VYN12_000143"
     CDS             49731..50090
                     /locus_tag="VYN12_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1414598.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50144..50893
                     /locus_tag="VYN12_000144"
     CDS             50144..50893
                     /locus_tag="VYN12_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1414599.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            50883..51182
                     /locus_tag="VYN12_000145"
     CDS             50883..51182
                     /locus_tag="VYN12_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1414600.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51253..52188
                     /locus_tag="VYN12_000146"
     CDS             51253..52188
                     /locus_tag="VYN12_000146"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1414601.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52274..52786
                     /locus_tag="VYN12_000147"
     CDS             52274..52786
                     /locus_tag="VYN12_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1414602.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            52823..53419
                     /locus_tag="VYN12_000148"
                     /pseudo
     CDS             52823..53419
                     /locus_tag="VYN12_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53520..53714
                     /locus_tag="VYN12_000149"
     CDS             53520..53714
                     /locus_tag="VYN12_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1414603.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(53760..55205)
                     /locus_tag="VYN12_000150"
     CDS             complement(53760..55205)
                     /locus_tag="VYN12_000150"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1414604.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55311..56933
                     /locus_tag="VYN12_000151"
     CDS             55311..56933
                     /locus_tag="VYN12_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1414605.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57136..59094
                     /locus_tag="VYN12_000152"
     CDS             57136..59094
                     /locus_tag="VYN12_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414606.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKSKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59266..60222
                     /locus_tag="VYN12_000153"
     CDS             59266..60222
                     /locus_tag="VYN12_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414607.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFEGGKSVSG"
     gene            60226..60948
                     /locus_tag="VYN12_000154"
     CDS             60226..60948
                     /locus_tag="VYN12_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1414608.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGKKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            61105..62199
                     /locus_tag="VYN12_000155"
     CDS             61105..62199
                     /locus_tag="VYN12_000155"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1414609.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            62207..63373
                     /locus_tag="VYN12_000156"
     CDS             62207..63373
                     /locus_tag="VYN12_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1414610.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSIKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTV
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            63466..66564
                     /locus_tag="VYN12_000157"
     CDS             63466..66564
                     /locus_tag="VYN12_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1414611.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREKDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            66612..67229
                     /locus_tag="VYN12_000158"
     CDS             66612..67229
                     /locus_tag="VYN12_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1414612.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKLVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            67240..68574
                     /locus_tag="VYN12_000159"
     CDS             67240..68574
                     /locus_tag="VYN12_000159"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1414613.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            68584..69048
                     /locus_tag="VYN12_000160"
     CDS             68584..69048
                     /locus_tag="VYN12_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414614.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKVIRLESPDELLSYFGMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            69045..69539
                     /locus_tag="VYN12_000161"
     CDS             69045..69539
                     /locus_tag="VYN12_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414615.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVDLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            69620..71275
                     /gene="mltG"
                     /locus_tag="VYN12_000162"
     CDS             69620..71275
                     /gene="mltG"
                     /locus_tag="VYN12_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1414616.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            71346..71828
                     /gene="greA"
                     /locus_tag="VYN12_000163"
     CDS             71346..71828
                     /gene="greA"
                     /locus_tag="VYN12_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1414617.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            72381..72779
                     /locus_tag="VYN12_000164"
     CDS             72381..72779
                     /locus_tag="VYN12_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414618.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            73224..74231
                     /locus_tag="VYN12_000165"
     CDS             73224..74231
                     /locus_tag="VYN12_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1414619.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSNVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKRTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            74306..74506
                     /locus_tag="VYN12_000166"
     CDS             74306..74506
                     /locus_tag="VYN12_000166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1414620.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            74541..75257
                     /gene="atpB"
                     /locus_tag="VYN12_000167"
     CDS             74541..75257
                     /gene="atpB"
                     /locus_tag="VYN12_000167"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1414621.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            75271..75765
                     /gene="atpF"
                     /locus_tag="VYN12_000168"
     CDS             75271..75765
                     /gene="atpF"
                     /locus_tag="VYN12_000168"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1414622.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            75765..76301
                     /locus_tag="VYN12_000169"
     CDS             75765..76301
                     /locus_tag="VYN12_000169"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1414623.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            76316..77821
                     /locus_tag="VYN12_000170"
     CDS             76316..77821
                     /locus_tag="VYN12_000170"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1414624.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVHFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            77837..78715
                     /locus_tag="VYN12_000171"
     CDS             77837..78715
                     /locus_tag="VYN12_000171"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1414625.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            78801..80207
                     /gene="atpD"
                     /locus_tag="VYN12_000172"
     CDS             78801..80207
                     /gene="atpD"
                     /locus_tag="VYN12_000172"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1414626.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            80218..80637
                     /locus_tag="VYN12_000173"
     CDS             80218..80637
                     /locus_tag="VYN12_000173"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1414627.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDNKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(80679..>80869)
                     /locus_tag="VYN12_000174"
     CDS             complement(80679..>80869)
                     /locus_tag="VYN12_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1414628.1"
                     /translation="KEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRI
                     FIALNIKKERTKFVLSRA"
BASE COUNT        24018 a        15086 c        18262 g        23503 t
ORIGIN      
        1 attttcctca ttttctagtg aaattgaact ttttctaaca tcttttgata gatgacttct
       61 taatcaatta tcatttccat tgttgtttct tggggtttca tcccttgtct ttgataaaag
      121 cggagagcac cctcgttatc attccagaca cttagggtta gattattgca gccaatttct
      181 ttagcataat agcagaaaaa tgacaataaa atagccccta gatattttga aaggaaagca
      241 taggggctat atagtttaat caaaataaag caaatctttg ctggtgcttg taaagaggtc
      301 gaagccatcc ttggtaacaa caccgcagtc ttcaatacga acaccgactt taccagggat
      361 atagatacct ggttcaacag agaagcacat gccttcttcg atgaccatgt cgtttccttc
      421 catgatagat gggaattcat ggacatccat accgatacca tgcccgagac ggtggttgaa
      481 gtactcacca taaccagctt tttcgatgac ctcacgggca gcgcggtcca cttcatgagc
      541 agtcacacct ggcttgataa agtcaagagc agcttgttgg gcttcaagag tcaagttgta
      601 aatatctttc ttgaattggt ctggtttgcc gacagcgact gtacgagtca tatctgacgc
      661 atagccattg accagaacac ccaggtcaaa gaggagaaga gcatcatttt caaccttatt
      721 agctgctgga atgccgtgtg gattcgcagc attatcacca gtcaagacca tggtatcaaa
      781 gctcatttca taaccttcac gtttcatggc aaagtcgatt tgtgcgatga tatctgtctc
      841 agtcttatca agagaaatat tgtcaaaacc aacatgaaca gccttgtcag cataaagacc
      901 tgcaaccatc attttttgca cttcatcagc tgatttgatg aggcgcatgc gttggatacg
      961 aggagtgagg ttgtcaaact cagcagtctc aaaaactgtt ttcaaaccat ggtatttggt
     1021 caagatgaga ttgtcaaact caacagcgac acgtttgaag tcaagttgtg gaagagcatg
     1081 tttgattttt tgccatggat tttcagaatc gacatagccc actactggga aggaaacggt
     1141 gctacttgca cgttctactt caagagctgg gacaaagagg agaggttcct gatccgctag
     1201 gacaaagagg aacatttggc gttcatgggg atcactgtaa aaaccagtga ggtaattgat
     1261 tgtgacgggg tcagatacga cagcgacgtc tagtttttct gattcaagat atgttaggat
     1321 ttgttgtaat ttagacatat gctaccttct ttctacccct ctattttggc aaaaaatgag
     1381 agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa ctccgacaag ataacggagt
     1441 tctttgatat cattttcctt tgtttaagaa aagtcagcct tgcttttgac gtcactgtac
     1501 tcttcagcga tttcttggct gagaatgtcc tcataggcag ggagttggat gtcctgacca
     1561 tatttcttct tgagggcagt agtaactagg cgataagcca gattggcatt acgagagagg
     1621 ataggcccgt ggaagtagga accaaagaca ttcttataat gaaccccttc accgaccttt
     1681 tcttcgttgt ttccatttcc atagacaacc tgtcccagcg gtttttggtc atcagagagg
     1741 aaggtacgac cttggtgatt ttcaaatcca tagtaggttt catcgaaatc ttcattgtga
     1801 atcttgatgt caccgataaa acggttattg gtctggttga gcgtgtagtg tcccatgacc
     1861 cctagccctt cgatacgttt tcctgaagct tcaacataat attgacccaa tagttggaaa
     1921 ccaccgcaga tagccagaac tacaccgtcg ttttggatgt agttgtcaat gctctctttt
     1981 ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt cttgaccacc accgaaaaag
     2041 gcgatgtcgt agtgattttc atcaaagtca tcatggagag aaacgatgtc aacggtcaca
     2101 tgggctccca gtttttcagc cacatacttg agcatgagga tgtttccatt gtccccgtag
     2161 gtattcatga gatttccgta gaggtgggca atgttgagct gataggggta attgctatct
     2221 tttgaggaaa gtgaagtata aaccattagt tcatctcctt tctaacaatc tgacgactag
     2281 ccagcagttc acgaaattcc agcatggcag tataagttgc cagaatatag gcatgcttgc
     2341 agtcttgatt ctcaatggtc ttgagaactt gctccagatt actcgtttca gtgattttct
     2401 cagctggata gccagtcact cggaggcgac gagcgatttc agaatgacga acaccgccag
     2461 cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa gtctgcatcc cagatccagc
     2521 tagtgtcaat tccatctgca tagttggcat taaggaggac agataggcta aatggataag
     2581 gtgctagttt gatcatttcg atagcttggg ttgcaccgac tggattttta atcaagacaa
     2641 gggtacattc cttgtcaccg atatgaaagg tttcttggcg tccaaagaca gcacggctct
     2701 tgtcaaatcc ctgtttgatg agttgggaat ctgcgccgag gaaacgggcg atggccacag
     2761 cagctagggc gttatagata ttatagagcc cgccgatttg gataccgtat tcttggccgt
     2821 ctatgacaaa gcgagagcga ttgttggtca actcaaccag ttttgtcaaa cgatagtcga
     2881 gatcaggacg tttacatcca caaccttcac agatataggc acccaagttt gcataggtat
     2941 tatgctcata tttgaggatg ccttggcagt caggacagag aatcccttcg gtattgtagt
     3001 gagcaagttg ggctggtcct ttttccaagt caaaaccaaa atactctata gggtttggaa
     3061 tagttggctt gtagaaaagt ggactgtctc cgttaaggag aacagtagca gttggaactt
     3121 ttcgaatggc atccaatatc atgttatagg tagtatagat ttcaccgaaa cggtccatct
     3181 ggtcacggaa gatattagta atgacaaaaa gactaggctg gatatagtca cagatacgag
     3241 atagactggc ttcgtcaatt tcgaggacgg caatattttt cccagttttt gaagatttgg
     3301 ctgttaggaa ggttgttgca atccctgtaa tcatgttggc accgcttggg ttggttagaa
     3361 cttgaccata aacctctttt aaaatgccga cagtgagggc agttgtcagg gtttttccat
     3421 ttgttccagt gacaacgaca atctcgtagt tcttagctag gctttgtaaa atatctttat
     3481 caaattgaag ggcgactttc cctgggagcg tacttccacg tccaagacgg cttaaaacga
     3541 agtgggaaga acgcccagca agaaggccca aagtagtttt taagttcatg tttctattat
     3601 atcacaaaag agggaaaaga cagatttggt gtttcgtaga agtaaaaaca gcccaaagag
     3661 ggctgtcagt taagatgaga tttcaactta aatcgcaaac aagtcattca agttctcagc
     3721 caaggttggg tgagtgaaga tttgttttgt gaagtaagtg taaggaatct tgttgtccat
     3781 agcaacagta atgatgttga tgatttcttg agaaccttct gagaagatgc ttgcaccaag
     3841 aatttctttt gtttcagtat taacaacagc tttgaaagct ccgcgaaggt ctccatttac
     3901 gtgaccacga ggcatggctg caacagggat ttctttcact gcgtatggaa gtttcaaatc
     3961 agctgcttgg ctttcagtca aaccaacttg tgaaagtgca ggtgtgatga acatagtatt
     4021 tggcacattg agacggtcct caagtgtgta gctgccatct ccagcaaggt agctgtaaac
     4081 aacacggaag tcatcaagtg aaatgtaagt aaattgaagg ccaccgttga catctccaac
     4141 tgcaaagaca ccaggaacgt ttgtttgaca gtgtttgtct actttaatag caccacgttc
     4201 agttagttca atatctgtat tttcaagttg aagtggttct acatttggtt tgcgtccagt
     4261 tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca gttacgacaa gcacttggtc
     4321 accatcgttt ttgatttcag tagtatggat attttgaagc aattcaatgc catcttcttc
     4381 catgtattgt ttagcaagag ctgcgatgga aggttctgca cgaggtagga atgtatccaa
     4441 ggcatctagg actgtgacct tgcttccaag tttgttgtaa aggccggcaa attcaagacc
     4501 gatatttccg ccaccaagga ttccaagttt ttcaggtaat ttgtccaagc tttggatacc
     4561 tgttgagtca aagatgtttt tgcttgtagc aagtccagga attggcaaga cgtttgaaac
     4621 agcaccagtg ttgatgacga ttgtttcagc agtcagttct ttcttttcat caccagcttg
     4681 gatttcgatg actttatttg aaaggaagtg agcttccgca tcaaagatat ctacgcctgt
     4741 accagcaaca gtcgcatagt ttttaccgtt gaggcgacca gtgatcgtgt ttttagtagc
     4801 aatcacttct tcaaaagaca agtccttttc agcagcaact agcaaggttt tagttgggat
     4861 acaaccaatg ttgatacaag ttccaccgta catagccttg ctgcgttcaa cgagggcaac
     4921 ttttttgcca gctgaagcca atttacctgc tagtgtttta ccagctttac caaatccaat
     4981 aacaattaaa tcgtatgtta acatttatct tcctcctatt cgaatttcat tctagcacaa
     5041 gaaaaaaact tttgcacaat tctgctacgg aaaagacaga aaaagataaa aacgctttcc
     5101 agacaaaaaa ctagtaattt tttgacaagc ttgataaact aaaatcctat ctatttttat
     5161 ataagaaaga ataaatgttc gaaaatagga ggttttatga aatcgaatcg ttatattatt
     5221 gcctttgctg gggtcatttt acacttaatg ctgggttcga cttatgcttg gagtgtttat
     5281 cgtaacccta ttattgaaaa aacgggatgg gatcaggctt ctgttgcctt cgcctttagt
     5341 ctagcaatct tttgtttggg cttatcggct gcatttatgg ggcgtttggt agaaaaattt
     5401 ggtccgaaag tcatggggag tctatctgct tttctatacg caggtggaaa tatcttaaca
     5461 ggatttgcaa tagaccgtca ggaactgtgg ttgttgtatc tagcttatgg cattttaggt
     5521 gggcttggtt tgggagcagg ctatattacc cctgtgtcaa cgattataaa atggtttcct
     5581 gataaacgtg gtctcgcaac aggtttagcg attatggggt ttggttttgc ttctttattg
     5641 actagtccca tagcgcaaca cctcatcgca ggggtaggga ttgtagaaac tttttatatt
     5701 ttaggagcaa gttactttat tatcatgctc ctagcttcac aattcattaa gcgtccaaat
     5761 gagcaagagc ttgcaatttt atcttcttca gggaaagaaa aaacagcctc tttgacgcaa
     5821 ggaatggctg caaatcaggc tctaaaaagc aatcggtttt atatgctttg gattattttc
     5881 tttatcaaca tagcttgtgg tttaggctta atttcagcgg catcgccaat ggcacaggag
     5941 atggctggct tgtctacaag tcatgcagca gtaatggtgg gtgttttggg gattttcaat
     6001 ggatttggtc gcttgctctg ggcgagtttg tctgactata tcggtcgccc tctaaccttt
     6061 agtatattac tgcttgtcaa tcttttcttt tctctctcac tttggctctt tacagattcc
     6121 gttttatttg tagttgctat gtctattttg atgacttgct atggagctgg tttttctttg
     6181 attccagctt atctcagtga tatttttgga accaaggaat tggccgctct gcatggttat
     6241 attttaacag cttgggcaat ggctggttta gcgggaccta ttttattagc agagacttat
     6301 aaaatggctc attcgtacac acaaaccttg ttcgtttttc tcattttata cagtatcgcc
     6361 ttggctttgt cttattatct aggtcgttca atcaaaaaag aaagtcaaaa accgcttaca
     6421 tgattttctg tagaaatggg gctatctttt gctctggtct tgtgttatac tagataggtt
     6481 gcaaagaaaa cagtactttt cttttgtgga aaagaagcaa cacgatttta tatctagtta
     6541 tatgaaaata cgtcataaaa agaaaagtat aaactaagcc ctatagggtg gcttcgcacc
     6601 acctttagaa agaagaataa cgtgaaattt aatgaattaa acttgtctgc tgatttgcta
     6661 gcagaaattg aaaaagctgg ttttgtagaa gctagtccta tccaagaaca aactattcct
     6721 ttggcccttg aaggcaagga tgttatcggt caagctcaga ctggtacagg aaaaactgca
     6781 gcctttggct tgcctaccct tgaaaaaatc cgtatagaag aagcgactat tcaagccttg
     6841 gtcatcgctc caactcgtga actagctgtc caaagtcaag aagaactctt ccgctttggt
     6901 cgtagtaagg gagtcaaagt ccgttcagta tatggcggat caagcattga aaaacaaatt
     6961 aaggctctta aatctggtgc ccatatcgtg gtgggaactc caggtcgcct cttggacttg
     7021 attaaacgca aggccttgaa attacaagac attgaaaccc ttatccttga cgaagcggat
     7081 gaaatgctta acatgggctt ccttgaagac atcgaagcca ttatttcccg tgtacctgag
     7141 aaccgtcaaa ctttgctttt ctcagcaact atgccagatg ccatcaaacg tatcggtgtt
     7201 cagtttatga aagcccctga acatgtcaag attgcggcta aggaattgac aacagaattg
     7261 gttgaccagt actatatccg tgttaaggaa caagaaaaat ttgacaccat gactcgtctc
     7321 atggatgtgg cacaaccaga actcgctatt gtatttggtc gtaccaaacg ccgtgtggat
     7381 gaattgactc gtggtttgaa aattcgtggc ttccgtgcag aaggaattca tggcgaccta
     7441 gaccaaaaca aacgtcttcg tgtccttcgt gactttaaaa atggcaatct tgatgttttg
     7501 gttgcgacag acgttgcagc gcgtggtttg gatatttcag gtgtgaccca tgtctacaac
     7561 tacgatattc cacaagatcc tgagagttat gttcaccgta tcggtcgtac aggtcgtgct
     7621 ggtaagtcag gtcaatctat tacttttgtt gctccaaacg aaatgggtta ccttcaaatc
     7681 attgaaaact tgactaagaa acgcatgaaa ggtctcaaac ctgcaagtgt agaagaatcc
     7741 ttccaatcaa aaaaacaggt agctctcaag aaaatcgaac gtgattttgc agatgaaacc
     7801 attcgtgcca actttgagaa atttggtaag gatgctcgca aattggctgc tgagtttact
     7861 ccagaagaat tggcaatgta tatcttgagt ctgacagtcc aagacccaga tagccttcca
     7921 gaagtggaga ttgcacgtga aaaaccacta ccgtttaaac catcaggtaa tggtttcggt
     7981 ggtaaagcta agggaggtcg tggaggccgt cgtggggacg accgtcgaga gcgtgatcgt
     8041 cgtggcaatg gtcgccgtga tgagttcaaa aaaggaagtc gtggcaacga tcgttttgat
     8101 aaggaaaaac gttaccgtaa ggataataaa aaaccacgca atactttaag cgaaaagcaa
     8161 acaggctttg ttattcgtaa caaaggtgat aaataagaaa aagcggttca aaatgaatcg
     8221 cttttttata taaggagacc gaatgtgaaa aagacaaata aaattattat attatctttt
     8281 ataatattat gatacacaaa aataggcgac ttgtcaatag aaaaggaaca atttaattaa
     8341 aaatattctg gtttttaatt aaattgtaag tcaatgcaag tcaataagga attttcagat
     8401 aattattgaa aaagagacgt ttttatgtta taatgatagc gattaaattc gaggtgaaaa
     8461 atggcacatt tattagaaaa aactagaaaa attacatcaa ttttgaaacg ctcagaggag
     8521 cagttgcagg atgagctccc ttacaacgct attacgcgtc agttagcgga tattattcat
     8581 tgcaatgcct gcattatcaa tagtaaggga cgtctgcttg gctattttat gcgttataaa
     8641 acaaatacag atcgcgtaga gcaattcttc caaactaaga ttttcccaga tgactacgtt
     8701 caaggggcta atatgattta cgaaacagaa gcaaacttgc ctgttgagca tgatatgagt
     8761 attttccctg ttgagagtag agatgatttt ccagatggct tgacgactat tgcaccgatt
     8821 catgtatcgg ggattcgcct tggttctttg attatttggc gtaatgataa aaaattcgaa
     8881 gatgaggact tggttcttgt tgagattgcc agtaccgttg ttgggattca gcttcttaac
     8941 ttccaacgtg aagaagatga gaaaaatatt cgtcgtcgta ctgctgtcac catggcggtc
     9001 aatacccttt cttactccga actccgtgct gtttcagcaa ttttagggga attaaatgga
     9061 aatgaaggga agttgactgc gtcagtgatt gcagatcgta tcggaatcac tcgctctgtg
     9121 attgtcaatg ctcttcgtaa acttgagtct gcggggatta ttgaaagtcg ctcacttgga
     9181 atgaagggaa cctatcttaa ggtcttgatt tcagatattt ttgaagaagt gaagaaaaga
     9241 gattactaat gacaaaggct ttaatttcga ttgattatac agaagatttt gttgctgata
     9301 gtgggaagct gacagcaggt gctccagctc aggcgatttc ggatgccatc agcaaggtaa
     9361 ctcgattagc ttttgaacga ggagattata tcttctttac tattgatgct catgaagaaa
     9421 acgattgttt ccatccggaa agtaagttat ttcctcctca taatctgatt gggacgagtg
     9481 gacggaattt atatggaaat ttggggatct tttatcaaga gcatggttca gacagtcgtg
     9541 tcttttggat ggataaacgc cattactcag ctttttcagg gactgaccta gatattcgtt
     9601 tgagagagcg tagagtgtct accgttatct taacaggtgt cttgacggat atctgtgtcc
     9661 tacatacagc tatagatgcc tataatctag gatatgacat cgagattgtt aaaccagctg
     9721 ttgcttccat ctggcctgaa aatcatcaat ttgccctagg tcatttcaaa aatacactcg
     9781 gagctaagtt agtagatgaa aatctaaatg aactttctga gtaacctggt tggtgaaaat
     9841 gaaaaaattt gaaaaaaagt gttgacaagc atcccaaaag ttgatatact agtaaagtaa
     9901 tcgatgcggg gatggcggaa ttggcagacg cgcaggacta aggatcctgt gaccgcttta
     9961 ggtcgtgagg gttcaagtcc ctctctccgc ataggaaaag agttagctaa agctagctct
    10021 tttgtatttc tctaaaaaat tagaatccag tcaaatgtag tggagaatca gcgaaaatat
    10081 gggaaaactg atccttgttt ctgcttttgt catagaagaa taataaagat tatcttcttc
    10141 aaattctccg atattctcta aagttttgtg caagttgcac agaacttttt tatttttttg
    10201 gtcatcttgc catagaaata taaagcgttt tcatctataa tataattatc aaaagacaaa
    10261 aggagttcac ctcatggtag aattgaatct taaaaatatt tacaaaaaat atccaaacag
    10321 cgaacactat tcagttgaag atttcaactt gaacatcaaa gataaagaat ttatcgtttt
    10381 cgtaggacct tcaggatgtg gtaaatcaac tacactccgt atgattgctg gtcttgaaga
    10441 catcacagaa ggtactgcat ctatcgatgg cgtggttgtc aacgacgtag ctccaaaaga
    10501 ccgtgatatc gccatggtat tccaaaacta cgctctttac ccacacatga ctgtttatga
    10561 caacatggct ttcggtttga aattgcgtaa atacagcaaa gaagacatta acaaacgtgt
    10621 tcaagaagca gctgaaatac ttggattgaa agaattcttg gaacgtaaac cggctgacct
    10681 ttcaggtggt caacgtcaac gtgttgccat ggggcgtgcg attgtccgtg atgcgaaagt
    10741 attcttgatg gacgaacctt tgtcaaactt ggatgccaaa cttcgtgtat caatgcgtgc
    10801 tgaaatcgct aaaattcacc gtcgtatcgg agctacaact atctatgtaa ctcacgacca
    10861 aacagaagcg atgacacttg cagaccgtat cgttattatg tcagctacta agaaccctgc
    10921 tggtacaggt actatcggac gtgtagaaca aatcggtact cctcaagaag tttacaaaaa
    10981 tccagttaac aaattcgttg caggattcat cggaagccca gctatgaact tcatcaacgt
    11041 gaaattggtt ggtagcgaaa ttgtttctga cggtttccgt ttgaaagtgc cagaaggagc
    11101 attgaaagtt cttcgtgaaa aaggctacga aggaaaagaa ttgatctttg gtatccgtcc
    11161 agaagacgtg aatgcagaac ctgctttcct tgaaacattc ccagactgtg ttgtaaaagc
    11221 gactatctct gtatcagaac tgcttggttc agaatctcac ctttactgcc aagttggtaa
    11281 agacgagttt gttgcaaaag ttgatgctcg tgactacttg caaacaggtg caacagttga
    11341 gcttggattt gacttgaaca aagcacactt cttcgatgta gaaactgaaa aaacaatcta
    11401 ctaagaataa ataaaattca aagcactaca agaaaagata tctctttatc aattgtagtg
    11461 gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt tgctagggaa
    11521 gtcatattat acatctatat tgtgatgctc tttatactct tcgaaaatct cttcaaacca
    11581 cgtcaacgtc gccttgccgt acgtatgatt actgacttcg tcagttttat ctgcaacctc
    11641 aaagctgtac tttgagtagc ttacggctag tttcctagtt tgctctttga tttccattga
    11701 gtattatttg tgggtaccat ctacaagtga agctatatgc gtaaactacg tgagcaattg
    11761 aattcgaact agagaggtaa taataaattt atgctatagt tatggtgact tgtatgcttt
    11821 tgattctagt ttatcaaata atagattaga attgtcagat aatatcattt tgtgttataa
    11881 tgaagaaaaa acagaggtgt tcaaatgtca gaagcaggtc ataagttttt agcaaaattg
    11941 gggaaaaaac gcttacgtcc aggtggaaag cgtgccacag attggttaat tgcagaagga
    12001 ggattttcaa aagaaaagag aatactagag gttgcgtgta ataggggaac tacagcaatt
    12061 gagttggcac agcgttttgg ttgcaagata actgctgttg atatggatgc tcaagcttta
    12121 gaagtggcta aaaaatctgc tggaacggca ggtgttgctc atttaatcag ttttgaaaga
    12181 gcaaatgcaa tgaaacttcc ttatcaagat gctagttttg atattgttat aaatgaagct
    12241 atgctgacta tgcaagccga tcaagctaag aaaaaatgtg taatggaata tctaagggta
    12301 ttaaaacctg gaggtcttct attgacgcat gatgtgcttc ttaaggaagc taaagagtct
    12361 atcagacagg aattatcaca agcaattcat gtaaatgtag gtcctttaac tcaagatggt
    12421 tgggaacagg tgatgataga atcaggttat tgtgatgtga aagtattgac tggtgaaatg
    12481 acattaatga aattatcggg tatgatttat gacgaaggtt tgctaggaac tttgaaaatt
    12541 tgtgtaaatg cttgtaaaaa ggagaataga aagcagtttt taactatgta taaaatgttt
    12601 gctaagaata aacagaaatt gggttttatt gcgatggcta gttataaatc gtcaaaacgt
    12661 tagataatta ttgaagttaa cttttccttt tttctttctt aaaaaatatg ctataataga
    12721 gagtaaaaaa ctttgaaaga aagaaaaaga tgaatttaaa agattacatt gcaacaattg
    12781 aaaattatcc aaaggaaggc attaccttcc gtgatattag tcctttgatg gctgatggaa
    12841 atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag aaagtcgaca
    12901 tgatcgtggg acctgaagct cgtggattta tcgtgggttg tccagttgcc tttgagttgg
    12961 gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc acgcgaagtt atttctgctg
    13021 actatgaaaa agagtacggt gtcgatacct tgactatgca cgcggatgcc attaagccag
    13081 gtcaacgtgt tcttattgta gatgaccttt tggcgacagg tggaactgtt aaggcaacta
    13141 tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt gttgaattgg
    13201 atgaattgaa cggccgtgaa aaaatcggtg actacgacta caaagttctt atgcattatt
    13261 aatgaaaaca gtccctaggg ctgttttctc tacactagga tataaaaata gactataact
    13321 agttagagaa aaactataat tgaaaactat atcttcttgc agtataataa aaggactaag
    13381 tgtttgagat ttgtcttcaa acatatgcaa ttattcctga aagagtacag ttaggagagg
    13441 gttatgccga ttcgaattga taaaaaattg ccagctgttg agattttacg gacagagaat
    13501 atctttgtca tggatgatca acgtgctgcc caccaagata tccgtccttt gaagatttta
    13561 attttaaatc tcatgccaca gaaaatggtc acagagaccc agttgttgcg ccacttggct
    13621 aatacacccc tacaactgga tattgatttt ctctatatgg agagccaccg ttctaaaaca
    13681 actcgttcag agcacatgga gaccttctat aaaacttttc ttgaagtcaa ggatgagtat
    13741 tttgatggga tgatcatcac gggtgctcca gttgagcatt taccatttga ggaagtggac
    13801 tattgggagg aatttagaca gatgcttgag tggtctaaga ctcatgtcta ttcgaccctt
    13861 catatctgtt ggggggctca ggctgggctt tatctgcgct atggtgtaga aaaataccag
    13921 atggacagta agctatcagg tatttatcct caggacaccc taaaagaggg tcaccttcta
    13981 tttagaggct ttgatgatag ctatgtatct cctcattcac ggcacacgga gatttctaag
    14041 gaagaggtct taaacaagac caatctcgag attttatcag aaggacctca ggttggggtt
    14101 tctattttgg ccagtcgtga tttacgagaa atttatagtt ttggtcattt ggagtatgac
    14161 cgtgatacct tggcaaaaga gtattttcga gatcgtgatg caggtttcga cccacatatt
    14221 ccagaaaatt actttaaaga tgatgatgtt aatcaggtac cttgtctttg ttggtcttca
    14281 tctgcagccc tctttttcag taattgggta aaccatgcgg tctatcagga gacgcctttt
    14341 gactggagaa agatagaaga tgatgcatct gcatatgggt atttataaga ggaattatga
    14401 catatttaga cgcttttaaa tcaggtacct tggttttacc gagtgccctg ctcttgcatt
    14461 ttaaggaact ctttccttct agcgacgatt ttctggtttg gcaatttttc tatttgcaaa
    14521 atacgacagg cttagaagaa atgtcgccaa gccagattgc tgaaaggatt ggcaaggaaa
    14581 tttcggatgt caaccagtcc atttctaatc tgacggaaag gggactgctc cagtatcgta
    14641 ctatcgaatt aaatggcgaa attgaattgc tctttgatgc tagtttggcc ttggaacgtt
    14701 tggatgacct gtttggagca gttcattcaa gttcagacca gctaacacct caaaaccagc
    14761 tcaaggattt ggtggaaacc ttccagcagg agttgggacg attgttgacg ccttttgaga
    14821 ttgaggattt gaccaagaca ctaaaggaag atggaaccag tgctgacttg attaaggagg
    14881 ctcttcgtga agctgttttg aatggaaaac caaactggaa gtacattcag gcgattttga
    14941 gaaactggcg ccatgaagga atcaagagtg tggctcaaat tgaggccaag agagcagaaa
    15001 gagaagcaag caatcctcag ttgatacagg tatctgcaga tttcagaaat gccatggatc
    15061 tctggaagga ttaatccatg caagtaggct tgaaatccga gtaagatttg caagctgtgt
    15121 ataattgtga tagaataaat agaaaataaa ttgaaaaaag aggtatgtga aatgtcacgt
    15181 aaaccattta tcgctggtaa ctggaaaatg aacaaaaatc cagaagaagc taaagcattc
    15241 gttgaagcag ttgcatcaaa acttccttca tcagatcttg ttgaagcagg tatcgctgct
    15301 ccagctcttg atttgacaac tgttcttgct gttgcaaaag gctcaaacct taaagttgct
    15361 gctcaaaact gctactttga aaatgcaggt gctttcactg gtgaaactag cccacaagtt
    15421 ttgaaagaaa tcggtactga ctacgttgtt atcggtcact cagaacgccg tgactacttc
    15481 catgaaactg acgaagatat caacaaaaaa gcaaaagcaa tctttgcgaa cggtatgctt
    15541 ccaatcatct gttgtggtga atcacttgaa acttacgaag ctggtaaagc tgctgaattc
    15601 gtaggtgctc aagtatctgc tgcattggct ggattgactg ctgaacaagt tgctgcctca
    15661 gttatcgctt atgagccaat ctgggctatc ggtactggta aatcagcttc acaagacgat
    15721 gcacaaaaaa tgtgtaaagt tgttcgtgac gttgtagctg ctgactttgg tcaagaagtc
    15781 gcagacaaag ttcgtgttca atacggtggt tctgttaaac ctgaaaatgt tgcttcatac
    15841 atggcttgcc cagacgttga cggtgccctt gtaggtggtg cgtcacttga agctgaaagc
    15901 ttcttagctt tgcttgactt tgtaaaataa tcagtaagta gcaaaagcta ggtggaacag
    15961 cattcagatg tctgttacat tttttatagg agagcaaaga ttgaaaacaa aaattggatt
    16021 agcaagtatc tgtttactag gcttggcaac tagtcatgtc gctgcaaatg aaactgaagt
    16081 agcaaaaact tcgcaggata caacgacagc ttcaagtagt tcagagcaaa atcagtcttc
    16141 taataaaacg caaacgagcg cagaagtaca gactaatgct gctgcccact gggatgggga
    16201 ttattatgta aaggatgatg gttctaaagc tcaaagtgaa tggatttttg acaactacta
    16261 taaggcttgg ttttatatta attcagatgg tcgttactcg cagaatgaat ggcatggaaa
    16321 ttactacctg aaatcaggtg gatatatggc ccaaaacgag tggatctatg acagtaatta
    16381 caagagttgg ttttatctca agtcagatgg ggcttatgct catcaagaat ggcaattgat
    16441 tggaaataag tggtactact tcaagaagtg gggttacatg gctaaaagcc aatggcaagg
    16501 aagttatttc ttgaatggtc aaggagctat gatgcaaaat gaatggctct atgatccagc
    16561 ctattctgct tatttttatc taaaatccga tggaacttat gctaaccaag agtggcaaaa
    16621 agtgggcggc aaatggtact atttcaagaa gtggggctat atggctcgga atgagtggca
    16681 aggcaactac tatttgactg gaagtggtgc catggcgact gacgaagtga ttatggatgg
    16741 tactcgctat atctttgcgg cctctggtga gctcaaagaa aagaaagatt tgaatgtcgg
    16801 ctgggttcac agagatggta agcgctattt ctttaataat agagaagaac aagtgggaac
    16861 cgaacatgct aagaaagtca ttgatattag tgagcacaat ggtcgtatca atgattggaa
    16921 aaaggttatt gatgagaacg aagtggatgg tgtcattgtt cgtctaggtt atagcggtaa
    16981 agaagacaag gaattggcgc ataacattaa ggagttaaac cgtctgggaa ttccttatgg
    17041 tgtctatctc tatacctatg ctgaaaatga gaccgatgct gagagtgacg ctaaacagac
    17101 cattgaactt ataaagaaat acaatatgaa cctgtcttac cctatctatt atgatgttga
    17161 gaattgggaa tatgtaaata agagtaagag agctccaagt gatacaggca cttgggttaa
    17221 aatcatcaac aagtacatgg acacgatgaa gcaggcgggt tatcaaaatg tgtatgtcta
    17281 tagctatcgt agtttattac agacgcgttt aaaacaccca gatattttaa aacatgtaaa
    17341 ctgggtagcg gcctatacga atgctttaga atgggaaaac cctcattatt caggaaaaaa
    17401 aggttggcaa tatacctctt ctgaatacat gaaaggaatc caagggcgcg tagatgtcag
    17461 cgtttggtat taagcgatga tttgaaagag ggatgtgata gtagcaccct ctttttcttt
    17521 gttttatgat agttcatcct cgagtaaatt caagatcttg ctcggaaatg aagcttatat
    17581 agtagattga atatagacaa ataccttgtg attggtaaaa cattttagaa attcatttac
    17641 ctttcctaat cgacttggtt tcatcttatt tcaatctatt atagtattgg ggaatttctt
    17701 caaaccacat cagcttggtc agttctacct gcgacctcaa aacttgtgct ttggtcaagc
    17761 tgggtttagt ttcctagttt gctgatggat ttccattgac tataagcatc caaccctctt
    17821 tttgtcttct aaagaattct taaattatca gtctattgca acttttctca tataagttct
    17881 ttgtcttgct attggttttc cttagtagta tactaaggta gtaatcatta agaagtggtt
    17941 acaaaaaata atgaatgagg taaagaaaat ggtagaattg aaaaaagaag cagtaaaaga
    18001 cgtaacatca ttgacaaaag cagcgccagt agcattggca aaaacaaagg aagtcttgaa
    18061 ccaagctgtt gctgatttgt atgtagctca cgttgctttg caccaagtgc actggtatat
    18121 gcatggtcgt ggtttccttg tatggcatcc aaaaatggat gagtacatgg aagctcttga
    18181 cggtcaattg gatgaaatca gcgaacgctt gattacactc ggtggaagcc cattctctac
    18241 attgacagag ttccttcaaa atagtgaaat cgaagaagaa gctggtgaat accgtaatgt
    18301 tgaagaaagc ttggaacgtg ttcttgttat ctaccgttac ttgtcagaac ttttccaaaa
    18361 aggtttggat gtcactgatg aagaaggtga cgatgtaaca aacggtatct ttgcaggcgc
    18421 taaaactgaa acagataaaa caatttggat gcttgcagcc gaacttggac aagcacctgg
    18481 tttgtaagaa ataaggaaac atagataaat ctgtaggaaa tttcttacag attttttcta
    18541 ttttgtaagc tattccaaac cagtcttttt ttgagttttt tgataaaata gtactatcag
    18601 tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt tgggcccagg atgaagaggg
    18661 tgtgattggt aaggaaaatc gtctgccttg gcatttgcca gcagaattgc agcactttaa
    18721 agaaacaact ctgaatcatg ctatcttgat ggggcgtgtg acctttgatg ggatggggcg
    18781 tcgcttgctt ccaaaacggg aaaccttgat tttgacgcgt aatccggaag aaaagataga
    18841 tggggttgct acttttcagg acgtccagtc tgttcttgac tggtatcagg ctcaagaaaa
    18901 gaatctctac attctcggtg ggaagcaaat ttttcaggct tttgaagctt accttgatga
    18961 agtgattgtc actcacattc atgctcgggt ggaaggagat acctatttcc ctgaagaact
    19021 tgacttgtct ctttttgaga cagtttcaag caaattttac gccaaagatg agaagaatcc
    19081 ttatgatttt accatccaat accgcaagag aaaggaagtc taatggaacg gagtttattt
    19141 ggtctattca cggcttttct gtgtttcatc tgctttctgg caggagcaca agcttttcgt
    19201 aaaaagcgtt acgggctttc tatcctcctt tggttaaatg cctttaccaa tctggtcaat
    19261 agtattcatg ctttttacat gaccttattt tagatagaat gacagtatag aatggaagga
    19321 aatcatgtct acaaatagaa aaaatgatat gatggtttat tgctcatttt gtggcaaaaa
    19381 ccaagaagaa gtacaaaaaa taattgctgg caacaatgct tttatttgta atgaatgcgt
    19441 ggagttagct caggaaatca ttcgagaaga attggttgag gaagtcttgg cagacttgtc
    19501 tgaggtgcca aaaccaattg aactcctcca tatcttgaac cactatgtaa ttggtcaaga
    19561 tcgtgccaag cgtgccttgg cagtggcggt ttataaccac tacaaacgca tcaatttcca
    19621 cgatacacgc gaagagtcag aagatgtgga tttgcagaag tcaaacattt tgatgattgg
    19681 cccaactggt tcagggaaaa ctttccttgc ccagaccttg gctaagagct tgaatgtacc
    19741 ttttgctatt gcggatgcga cagctctgac ggaggctggt tatgtgggtg aggatgtgga
    19801 aaatatcctc ctcaaactct tgcaggttgc tgactttaac atcgaacgtg cagagcgtgg
    19861 cattatctat gtggatgaaa ttgacaagat tgccaagaag agtgagaatg tgtctatcac
    19921 acgtgatgtt tctggtgaag gggtgcaaca agcccttctc aagattatcg agggaactgt
    19981 tgctagcgtg ccgcctcaag gtggacgcaa acatccacaa caagagatga ttcaagtgga
    20041 tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat ggtattgaag aaattgtcaa
    20101 acaacgtatg ggtgaaaaag tcatcggatt tggtcaaaac aataaggcga ttgacgaaaa
    20161 cagctcatac atgcaagaaa tcatcgctga agacattcaa aaatttggta ttatccctga
    20221 gttgattgga cgcttgcctg tttttgcggc tcttgagcaa ttgactgttg atgacttggt
    20281 tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa taccaaacct tgctttctta
    20341 tgatgatgtt gagttggaat ttgacgacga agcccttcaa gagattgcta ataaagcaat
    20401 cgaacggaag acaggggcgc gtggacttcg ctccattatc gaagaaacca tgctagatgt
    20461 tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt cgcatcacta aagaaactgt
    20521 cgatggaacg gataaaccga tcctagaaac agcctagagg tgactatgga acttaataca
    20581 cacaatgctg aaatcttgct cagtgcagct aataagtccc attatccgca ggatgaactg
    20641 ccagagattg ccctagcagg gcgttcaaat gttggtaaat ccagctttat caacactatg
    20701 ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg gtaaaaccca gctcctgaac
    20761 ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc ctggttatgg ctatgcccgt
    20821 gtttctaaaa aggaacgtga aaagtggggg tgcatgattg aggagtactt aacgactcgg
    20881 gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc atgacccgtc agcagatgat
    20941 gtgcagatgt acgaatttct caagtattat gagattccag tcatcattgt ggcgaccaag
    21001 gcggacaaga ttcctcgtgg taaatggaac aagcatgaat cagcaatcaa aaagaaatta
    21061 aactttgacc caagtgacga tttcatcctc ttttcatctg tcagcaaggc agggatggat
    21121 gaggcttggg atgcaatctt agaaaaattg tgaggaaaag aaaatggcaa aaacaattca
    21181 tacagataag gccccaaagg ctatcggacc ctatgttcaa ggaaaaatcg ttggcaacct
    21241 tttgtttgct agcggtcaag ttcccctatc ccctgaaact ggggaaattg taggagagaa
    21301 tatccaagaa cagacagagc aagtcttgaa aaacatcggt gctattttgg cagaagcagg
    21361 aacagacttt gaccatgttg tcaaaacaac ttgcttcttg agcgatatga acgactttgt
    21421 tccttttaat gaggtttacc aaacggcctt caaagaggaa ttcccagctc gttcagctgt
    21481 ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt gaagtcatcg cagagattgg
    21541 ataagctagt tgaagtttgg tgttgccaaa cttcttttga tataaggaga aaaagatgac
    21601 aaagaaacaa cttcacttgg tgattgtgac agggatgagt ggcgcaggga aaactgtagc
    21661 cattcagtcc ttcgaggatc taggttattt caccattgat aatatgccgc cagctctctt
    21721 gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat cctaagttgg ccttggtagt
    21781 ggatatgcgt agccgttctt tcttttcaga gattcaagct gttttggatg agttggaaaa
    21841 tcaagatggt ttggatttca aaatcctctt tttggatgcg gctgataagg aattggtcgc
    21901 tcgttacaag gaaaccagac ggagtcaccc actagcagca gacggtcgta ttttagatgg
    21961 aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat atgagccaaa atgtggtgga
    22021 tacgactgaa ctcactccac gtgagctgcg caaaaccctt gcagagcagt tttcagacca
    22081 agaacaagcc cagtctttcc gtatcgaagt catgtctttc ggatttaagt atggaatccc
    22141 gattgatgcg gacttggtct ttgatgtccg tttcttgcca aatccctatt atttaccaga
    22201 actgagaaac caaacgggtg tggatgaacc tgtttatgat tatgtcatga accatcctga
    22261 gtcagaagac ttttatcaac atttattggc cttgattgag ccgattctgc caagttacca
    22321 aaaggaaggt aagtccgttt tgaccattgc catgggatgt acgggtggac aacaccgtag
    22381 tgtggcattt gctaaacgct tggtgcagga cttatccaag aattggtctg ttaatgaagg
    22441 gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt tcatgagaaa accaaagata
    22501 acggtgattg gtggagggac tggaattccc gtcattctaa aaagtctgcg ggaaaaagat
    22561 gtggaaatcg cagctatcgt gacggtggca gatgatggtg gttcttcagg tgaactccga
    22621 aaaaatatgc aacagttgac accgccaggt gatcttcgta atgtccttgt ggccatgtcg
    22681 ggtatgccta agttttatga gaaggtcttt cagtatcggt tctctgagga tgccggagcc
    22741 tttgctggcc atccattggg aaatctcatc attgctggct tgtcagaaat gcagggttca
    22801 acctataatg ccatgcagtt attgagcaaa tttttccata caacagggaa aatttatcct
    22861 tccagtgacc atcctttgac ccttcatgca gtctttcagg atgggacaga agtggctgga
    22921 gagagtcata ttgtagacca tcgaggcata attgacaatg tctatgtgac caatgcccta
    22981 aacgatgata cgcctctggc cagccgtcga gtagtgcaga ccatccttga aagtgacatg
    23041 attgtcctag ggccaggttc cctctttacc tctattttgc ccaatatcgt gattaaggaa
    23101 attgggcggg ctcttttgga aaccaaggca gaaattgcct atgtctgcaa tatcatgacc
    23161 caacgtgggg agacggaaca ctttacagat agcgaccacg tggaagtctt gcatcgtcac
    23221 cttggtcgcc cttttatcga cactgtcttg gtgaatattg aaaaagtgcc tcaggaatac
    23281 atgaattcca accgttttga tgaatacttg gtgcaagtgg aacacgattt tgtaggtctt
    23341 tgtaagcaag tttcgcgcgt gatttcatct aacttccttc gtctggaaaa tggcggtgcc
    23401 ttccacgatg gagatttgat tgtggacgag ttgatgcgca ttatacaggt gaaaaaatga
    23461 gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca ccatctgagc tggcatgaat
    23521 tatctgccat tatcaaaatg tctggtagca tcggtctctc gacttcgggc ttgactttgt
    23581 cagttgtgac agaaaatgcc aaactggccc gtcacctcta tgagtccttt ctccatttct
    23641 atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa tcttcgcaag aatcgcgtct
    23701 ataccgtttt tacagatgaa aaggtgcagg atttgttaag tgatttgcac ttggcagact
    23761 ctttctttgg cctggaaaca ggtattgatg aggcgatttt atcggatgag gaagcaggtc
    23821 gtgcctatct ctgtggcgct ttcttggcaa atgggagcat tcgtgaccct gagtcaggca
    23881 agtaccagtt ggaaatcagt tctgtttatc tggaccacgc gcaaggaatt gcctcccttc
    23941 tccaacagtt tttactggat gccaaggtgc ttgagcgcaa gaagggggct gtgacctatc
    24001 tccagcgagc agaagacatt atggacttct tgatagtaat cggagccatg caggcacgtg
    24061 atgattttga gcgggttaag attttgcgag aaacccgtaa cgacctcaat cgggctaata
    24121 atgccgagac agctaatatc gctcggacag tttctgccag catgaagacc attaacaata
    24181 tcagtaaaat caaagatatc atgggcttag aaaatttgcc agtagatttg caggaagtgg
    24241 cgcaactgag aattcagcac ccagactact ctatccagca gttagcagat agtctcagca
    24301 cccctctgac caaaagtggt gtcaatcaca gactcagaaa aatcaataag atagcggatg
    24361 aattataaaa ccacgaatcc tatgtgactc gtggttcttt tttataaact agtagagtgt
    24421 tttggttgta ctttttgttc agggtcaatg tagttgatag cgttgttgac agcagttgga
    24481 gcttctccga ggcctgtcgc aatcagatca atttttccgt catagtagca gcagtcaccg
    24541 atagcataga tacctgcttg gctggattcc tgtttgctgt tgacgataat cttgtgacgg
    24601 ttgaggtcga gcccccagtt tttaaggtta ccgacagaag atttgaaacc atagttgaca
    24661 aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt tgacttttgt gatttcaagt
    24721 ttatcaagtg tttttccatt tccaaggagt tggctagggg cgaatggtgt cttgatggtt
    24781 acagatgatt cttgcaaggc ttgaacactg tgttccaagg cacggaaatt atctctgcgg
    24841 tgaacaaggg tagttggtgc gattttttca aaagccaaag cccaatccac agccgagtct
    24901 cccccaccaa gaatcgtcac tttcttacca gcgtattgct gaatgttaga aacgtggtag
    24961 tggatatttt catagccctc aacactttca agttccagcg gacgtggttt gaaggcaccg
    25021 ccacccatag cgatgataac tgttttagtc aggtgacttc ctttagaagt tgtgatggca
    25081 aattcttctt gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat
    25141 ccatttagct gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct
    25201 ggtacgtcta ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga
    25261 agagagtcga tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc
    25321 ccgacaggac caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg
    25381 ttttttctag tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg
    25441 gaaaaaaata ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag
    25501 ggatgaattt tcaacaatta tccaatctgc aatattggac cagtttgttt gcaagtccat
    25561 ggacgatagc tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta
    25621 caaaagctat tgcaggaacc aagattatga ttttggtacg tggagttttg gtgtttattt
    25681 tagctcaaat ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa
    25741 ttattactta tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt
    25801 tggaacgttt gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac
    25861 agatgattcg tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct
    25921 tggttgctat tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg
    25981 atgctaagat ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg
    26041 atggtgcggt gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga
    26101 caaaaaacac agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat
    26161 cagaagtctc agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa
    26221 cctataatgg aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg
    26281 aaatcttact tccaaaagag gaagtgggtc ttagttttaa agaacgattg ctaggaggat
    26341 ggaaacatga aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta
    26401 tttgtctatg ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg
    26461 gaaacctata ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag
    26521 tattttatta gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta
    26581 tcgctagcta gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca
    26641 gatgccggtg ttggaacgat tgaagttcct ttgagcattg aagatttacc caatgggctg
    26701 accgctgtgg cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat
    26761 aaggtaaaga ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa
    26821 aatgtcatgg tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga
    26881 attgataaga ttatcgctgt tttgccaact agcgaacgta taacaggtaa ttacagtggt
    26941 tcagtacctt tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg
    27001 tttgatacaa taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat
    27061 tcaagtacaa gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg
    27121 aattaaaaat agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc
    27181 gtggagaagc taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag
    27241 gctatgttct tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac
    27301 gtatttcagg ggaaatgttg gaatcggcct tggtggcagg tctcctttca gtagggattc
    27361 acgtatacaa acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag
    27421 gagcaagtgc cggtgtcatg atttctgcta gccacaaccc agcccttgat aacggaatca
    27481 agttctttgg cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct
    27541 tgctagatgc tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg
    27601 tagattatcc agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc
    27661 ttgatggaat gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc
    27721 aaatctttgc agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta
    27781 acatcaacct taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa
    27841 gtgggtcagc tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg
    27901 agaatggtga catcgttgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg
    27961 aaaaaggaca attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc
    28021 acaaggcctt gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg
    28081 ttgttgaaga aatgagaaaa tcaggctaca accttggtgg tgaacagtct ggtcacgtta
    28141 tcttgatgga ttacaatacc acaggtgatg gtcaattatc agcagttcaa ttgactaaaa
    28201 tcatgaagga aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac
    28261 aaaaattagt taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag
    28321 ctatcaaggc catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg
    28381 ttcgtccaag tggaacagaa cccctcttgc gtgttatggc agaagcgcct acaacagaag
    28441 aagtaaacta ctatgttgat accatcacag atgtagttcg tgctgaaatt gggattgact
    28501 aaatcctaga aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag
    28561 ccgatggaga aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt
    28621 gatgcgcgta attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg
    28681 aatttccaat tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcatcttg
    28741 agctttatga ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat
    28801 atcgatggcc gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg
    28861 gctcgtccat gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta
    28921 gacttaccag gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc
    28981 tgcttatctc agtgcagaga tcttgcaaag agaagacttg tttgtcttgg atattcctgt
    29041 caatattgat ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca
    29101 aaaaatggct caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga
    29161 tgaaatctta acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc
    29221 ttctggaatt tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt
    29281 aaccattgct ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag
    29341 cgtctttaat tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat
    29401 tcaaatcagc cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg
    29461 tggacgcctt tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct
    29521 ttattttaac gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc
    29581 caccaaacgc ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat
    29641 tgtcattcat gggaatgctc ctgaaaaggc tgaagaattg cgtcagcatt tgcttgattt
    29701 tggcttgggt tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg
    29761 agcaggaagt attgctctag gttatattcc agtgatttag ttggcacttc taggctagtt
    29821 aatcttagaa attgaacacg gactacctgc ctcttgaaaa aagatgcctg tcttgccttt
    29881 cgtggaaagt cagtgccatt ccctattttt caggggcagc taaggtcctt tgtatcttga
    29941 taattgaaca cgcctggaac cctgtgtgaa aaagatagtt cttccaagaa gtagacactt
    30001 cttgatcaga attcctattt tcactttgtg ttcttacagg ctttgtattt tggacaggag
    30061 tagagatgag tattcgagta attattgccg gttttaaggg aaagatgggc caggctgctt
    30121 gtcagatggt attgactgat ccagacttgg acttggtagc agttttggat ccttttgagt
    30181 ctgagtcaga atggcagggt attcctgttt tcaaggataa ggctgattta gctggttttg
    30241 aagcggatgt ctggatagat tttactactc cagctgttgc ctacgaaaat acacgttttg
    30301 ctcttgaaaa tggctttgct ccagtagttg gaacgactgg tttcacgagt gaagaaattg
    30361 cagagctaaa agaattttct cgtgcccaag acttgggtgg cctgattgcc cctaactttg
    30421 ccttgggtgc tgtcttactc atgcaatttg cgacgcaggc tgccaaatat ttcccaaatg
    30481 tggagattat tgagctccat catgacaaga aaaaggatgc tccgagtgga acagccatta
    30541 aaacagctga gttgatggca gaggttcgag agtcaattca gcaaggtgca gcagatgagg
    30601 aagagctgat tgctggtgct cgtggtgctg actttgatgg tatgcgcatc cactcagttc
    30661 gtttgccagg cttggtagct catcaggaag tcatctttgg caatcaggga gaagggttga
    30721 ccctccgtca tgactcctat gatcgcatct ccttcatgac aggagtcaat ttgggaatta
    30781 aagaagttgt caagcgtcat gagcttgtct atggattaga acacttatta tgagattaac
    30841 gcaaatgcct tctgaatttc agaaggcttt accagtatta gaaaaaatta aagaagcagg
    30901 ctttgaggct tattttgttg ggggctctgt tcgagatgcc cttctccata gccctatcca
    30961 cgatgtggat attgcgacgt cttcttatcc agaagagacc aagcagattt ttccgcgaac
    31021 agccgatatc ggaatcgagc atggaaccgt cttggtctta gatggggatg aggagtatga
    31081 ggtaacaacc tttcggacag aggatgtcta tgtggactat cgcagaccca gtgcggtttc
    31141 ctttgtgcgc tcgctagaag aagacctcaa acgccgtgat ttcacagtca acgcctttgc
    31201 cttggatgag acaggagaaa tcgttgactt gttccatggt ttagaagatt tggaaaagca
    31261 agtcttgcga gcagttggag tggctagtga gcgtttcaac gaagatgctt tacggattat
    31321 gcgtggtttc cgttttcagg ctagtcttgg ttttgcactt gagccagaaa catttaaagc
    31381 tatgaagacc ttgacgccgc ttttggagaa aatttctgta gagcgtacct tcgtcgaatt
    31441 tgataaactc ttgctggctc cattttggag aaggggcttg gcttccatga ttgagagtca
    31501 agcttatgac tatctccctg atatggcatc tagccaggac aagctcaaca gactgtttga
    31561 tttggagact gattttactt ttgaatcctc tgaacaagcc tgggcggctt tactatgggc
    31621 tttggagatt gaaaatgcgc agtcattttt gaaatcttgg aagacctcac gccagtttgc
    31681 caagcaagtt caggatttgc tgattatttt ggctctgcgt gaaaatggag aattgagcaa
    31741 gcgagattgt tatcgctttg acatagattt gcttttacag gctgaaaatc ttcgtcaagc
    31801 tcaaggaaaa gaagtcaacc cacaagccat cacagaaaaa taccaaagct tgactatcca
    31861 tgacaagaaa gagattcaga ttaatggcga tattttgatc aaggaatatg gctatcagcc
    31921 aggcccagac ttgggagaga ttttaacaga gattgagttt gccattgtcg atggagaatt
    31981 ggagaataat cgtgaagcca tccatgctta cctgagggag aaaaaatgag tgattttatc
    32041 gttgaaaaac taagtaaatc cgttggtgac aagaccgttt ttagggatat ttcctttatt
    32101 atccatgact tagacagaat tggtttaatc ggtgtcaatg ggactggcaa gaccaccctt
    32161 ttggacgtcc tttctggtgt ttctggattt gatggggatg tcagtccttt ttcagctaaa
    32221 agtgattacc agattggtta tttgactcag gatcctgatt ttgatgatag aaagacagtt
    32281 ttggatacgg ttctatctag tgaactcaag gaaatccagc tcattcgtga gtatgaattg
    32341 attatgctcg actatagtga ggacaagcag gcgcgtttgg aacgtgtcat ggcagagatg
    32401 gactctctcc aagcttggga aatcgagagt caggtcaaga ccgttcttaa caaattgggc
    32461 attcaagact tatctactcc tgttggggaa ttgtcaggtg gtctgagaag acgggtacag
    32521 ttggcacaag tcttacttgg caaccacgac cttttgcttt tggatgagcc gaccaaccat
    32581 ctggatattg cgattattga gtggctgacc ctctttttga aaaattctaa gaagaccgtc
    32641 ctttttatca ctcacgatcg ttatttctta gacgctttgt caacacggat tttcgagttg
    32701 gagcgagcag gcttgacaga atatcagggc aattaccagg actatgttcg ccttaaggca
    32761 gaacaggacg agcgcgatgc agctctactt cataaaaaag aacaactcta caaacaagaa
    32821 ctggcctgga tgagcagaca accgcaggcg cgtgcgacca agcaacaagc tcgtatcaat
    32881 cgtttccatg atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga cttgactatg
    32941 aactttgaaa ccagtcggat tgggaagaaa gtcatcgagt ttcaggatgt ttcctttgcc
    33001 tatgaaaata agcccatttt gcaagatttt aatctcttag ttcaggctaa agaccgtatt
    33061 ggaattgttg gggacaatgg tgttggaaaa tcaaccctac ttaacctgat tgcaggaagt
    33121 cttgagccga cagcaggaca agttgtgatt ggggaaactg ttcgcatcgc ctatttctct
    33181 caacaaattg agggtttgga tgaaagcaag cgtgtgatca attacctgca ggaagtggca
    33241 gaggaggtca agaccagtgg tggttctacg acttccatcg ctgagttgct ggagcaattc
    33301 ctcttcccac gttcgacgca tgggaccttg attgagaagt tgtcaggggg tgagaaaaaa
    33361 cgtctttatc tcctcaaact gcttttggaa aaaccaaatg ttcttctttt agacgagcca
    33421 accaatgacc tagatattgc aactttgaca gtcttagaga atttcttgca aggttttgca
    33481 ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc gaccaagatt
    33541 ctcgcttttg aggatggcaa gattcgtcct ttctttggtc attacaccga ctatcttgat
    33601 gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa ggaaaaagtg
    33661 gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga gtgggcaagt
    33721 attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga ggaaatgcag
    33781 gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga tgagaaaaat
    33841 gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga tagttaagac
    33901 tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa gtacagcctg
    33961 cgaccggctt cctaatttgc actttgattt ttattgagta taaacgaata gaaaaatctc
    34021 gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata ttttgccagg
    34081 tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag cagatgagtt
    34141 tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt aactcttttt
    34201 tggtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag acaaaatcat
    34261 cagtcaagag ttcttctagt tggtttcctt ggtcaatcaa ttgttcacgc ataagcaatt
    34321 ttttatagac attgtctaaa atttcatcct caaggatagg tgctggttcg atatggacat
    34381 cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc gcgatttcat
    34441 ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg tagatgttgc
    34501 taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt tccatgatag
    34561 ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta aaggaagact
    34621 agatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata gcaaccagtt
    34681 tatccacaat cggataattg aaactactag ctaggatggc aatggcggtt ccaagtgagg
    34741 taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag ttggatttct
    34801 tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa atgattccta
    34861 gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt tgaatggtat
    34921 ctcttagaac atcgaaaccg acatagaaca tgatgataga agtgatcaag cttgccaaat
    34981 cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc gccatccgaa
    35041 tcccgattaa gagggctaca tttccaatga tgtccgatac gttattaaaa ccatcggcca
    35101 ccaaactgga tgaatgaagg agatgaccag ctgctaattt ggctgcagac aagatcaaat
    35161 aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag atagattgct
    35221 tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt tcaaggaaaa
    35281 attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat aatggtacta
    35341 ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt ttatgctgaa
    35401 aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac aggtctcttt
    35461 ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa tgtcaaggag
    35521 gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc ctgaagaggt
    35581 cttgcaggct atggatgcga ccgagcaagg tttgtcatca agtgaggcgg aaaagcgcct
    35641 tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct tggtcaaatt
    35701 catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa tcttgtcagt
    35761 cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg tggttatcat
    35821 caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctattg aagccctcaa
    35881 atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag agattgactc
    35941 taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg taccagcgga
    36001 cctacgtttg atagaagcca actctcttaa aattgaagaa gcagccttga caggtgaatc
    36061 tgtaccagtc gaaaaagact tgtcagtcga gcttgcgaca gatgctggta ttggtgaccg
    36121 tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg gtgttgttgt
    36181 caatacaggt atgtatactg aagttggtca tattgctggt atgcttcaag atgcggatga
    36241 gactgataca ccactcaaac aaaacttgaa caacctttct aaggtcttga cctatgctat
    36301 cttggtcatt gcccttgtta cttttgtagt gggtgtcttc attcaaggga aaaatccact
    36361 tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag gacttcctgc
    36421 tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac attccatcgt
    36481 tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt ctgataagac
    36541 tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg cggttctaca
    36601 tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt cagttgtctt
    36661 ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa ccgaaacagc
    36721 ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag agaaatatcc
    36781 tcgtgtagct gaattgccat ttgcctctga ccgtaagctc atgtcaacag ttcacccatt
    36841 gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct taaaacgttg
    36901 tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta caaatctcat
    36961 tcatacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag gtgcttataa
    37021 gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg atttaatttt
    37081 tactggtttg attgggatga ttgaccctga acgtcctgaa gccgctgagg ctgttcgtgt
    37141 ggctaaggaa gcgggaatcc gtccgattat gattacaggt gaccaccaag acacagcgga
    37201 agccattgcc aaacgtttgg gaatcattga cgcaaacgat acagaaggtc acgttttaac
    37261 tggtgctgaa ctcaatgaac tgtcagatga agaatttgaa aaagtcgttg gtcaatactc
    37321 tgtttatgcc cgtgtgtctc cagaacacaa ggttcgtatc gtcaaggctt ggcaaaaaca
    37381 aggtaaagtc gttgccatga caggtgacgg tgtcaatgac gcgccagctc tgaaaacagc
    37441 cgatatcggt atcggtatgg gaatcactgg tacagaggtt tctaaggggg cttctgatat
    37501 gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag gacgtaaggt
    37561 cttctcaaac attcaaaaga ctattcagta cctactttct gctaatactg ctgaagtatt
    37621 aaccatcttc ctatcaacct tgtttggttg ggatgtcttg cagccggttc atcttttgtg
    37681 gatcaacttg gtaacggata ccttcccagc tatcgctctt ggtgttgaac ctgcggagcc
    37741 tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag gtggtgtttt
    37801 gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg tttatggcct
    37861 tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag atgccctaac
    37921 gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg tcaagtctgt
    37981 ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact ggtccatctt
    38041 ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag gaatcttcca
    38101 cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct tctcaatgat
    38161 tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca agaatgcgat
    38221 ttaagggagg tttcggatgt cagcatatca attaccgacc gtatggcagg atgaagctag
    38281 taatcaagga gcttttacgg ggctaaacag accaacagca ggtgcccgtt tcgaacaaaa
    38341 cttgccaaaa ggagaacaag ctttttagct ttattcactg ggaacaccaa atggtgtgaa
    38401 ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg cttacgactt
    38461 gtataagatt gctatcatgg atggggatca attcggctca gactttgtga agctcaatcc
    38521 aaattccaag attccagcct tattggacca gtcaggtact gaaaacgtaa gagtctttga
    38581 gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac caagtaatcc
    38641 tgtggaaaag gtagaagttt tgaattggct attctggcaa gcaggtgcag caccttttct
    38701 aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat atcctattaa
    38761 ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat tggctcagaa
    38821 accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt cttggtatgg
    38881 acagttagtt caaggaaatc tttaccaagg ttctgcaaaa ttcttggatg cctcaagtta
    38941 tcaaaatcta gtaaaatggg cagaaaaagt tgccaatcgt ccagctgtta agcgtggctt
    39001 ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg ctttttgcta
    39061 cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta taatatagta
    39121 aaaagcaaga ggagtgtgag gaagtggaaa agaaaattgt gaaggatatc ttatttttat
    39181 ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat ttgcaggata
    39241 cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt ggggtgcaga
    39301 agcgcgtgat tatctttaat cttggcttgg ttcctgtggt catgtttaac ccagtgcttc
    39361 tgtcctttga aggatcctat gaggcagaag aaggctgttt gtccttggta ggtgtgagat
    39421 caactaagcg ttatgaaacc ataaggcttg cctatcgtga cagcaagtgg caggaacaga
    39481 ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat cacttggaag
    39541 gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta tttttatcgc
    39601 aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat ttctcttctt
    39661 cctctgtggg catttgttag ttgtggcaat attatttggc tttggcaagg ggataaacct
    39721 tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc ttgagggttt
    39781 caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc ttctcttggc
    39841 agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg ccaatgtagt
    39901 cacggttacg gaaaaagact ttactgaatt tcctaagagt gacaccagta aggttcctat
    39961 cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc taaccgataa
    40021 ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg ggaaacctta
    40081 tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc aagccaaggg
    40141 aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg tggacttgaa
    40201 gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac gtcacctgcg
    40261 cttgaagtac ccgaccaaaa tctttaaaac tccatctttt gaggtggacg atgagggcaa
    40321 tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgcggttc ctcgtcctgc
    40381 ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct tatcagatgt
    40441 tccagaatgg gtggacagga tctatccagc agaggaaacc attgagcaaa ttaactacaa
    40501 cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaacg tgacccagac
    40561 taccaagggc tataattact tgtctatcgg taatgacatc tatctctaca caggtgtgac
    40621 gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc gaacaggaga
    40681 aatcactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat cagcagaagg
    40741 tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc tcaatgacaa
    40801 gcctctctac atcatgggct taaaggacaa tgctggcttg gtcaaagagt acgccctggt
    40861 agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga tgctcagcaa
    40921 gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca tcaagggagt
    40981 agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct ttaaagttga
    41041 tggcaagata tacaaggtca aggcttcagt atccgatgac cttccttacc ttgaaaatgg
    41101 taaaaccttc gaaggtcaag taggaaaaga caattatctc aagaccttta aagtacaata
    41161 atactcttcg aaaatctcta gctctatctg caacctcaaa acagtgtttt gagcagcctg
    41221 cggctagttt cctagtttgc tctttgattt tcattgagta taaaaaaggt ttatttaata
    41281 aatatatgtt ataataaggt aaattaagcc taatggagga caaagaaatg ggtttttatt
    41341 tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt tctcagttca
    41401 aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca gcccttgttc
    41461 tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca aaccgaggtt
    41521 tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat atgaaaattt
    41581 taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca attcctttaa
    41641 aaccagaaag tcagaccgtg cttgatgcct tggctctcta ttctgccagt caattggaga
    41701 gtttctacaa ggtatcggct gagaaagcgg cggaagaatt tcaaaatatc caagctttga
    41761 aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt atgtaccgca
    41821 acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat catgtcttca
    41881 ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct caccgtttgg
    41941 attttttgat gaaattaaaa gtcgctggta agactttgaa gagccattgg aaggcagtct
    42001 atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca gagtttgaga
    42061 ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg gaggatagag
    42121 gcggtcagct gaagattcac tcaactatct ccaagaaagc gcgcggggcc tttctaacag
    42181 ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac tttgctggat
    42241 ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag gaagtataga
    42301 aatcagatat tttgtatttg gcaatatgta tcatcagctg ttttagttta taaatgagaa
    42361 aaaaagcgaa caagctagtc ttctgagtgt cagaaaagta gtcttgttcg cttttattat
    42421 gttatactct tcgaaaatct cttcaagcca cgtcagcgtc gccttaccgt atatatgtca
    42481 ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagcagct tgcggctagc
    42541 ttcctagttt gctttttgat ttttattgag tgttagttac ttgatagctt cgaccaagtc
    42601 ttgagcttgt ttttcaagtg agtttaggac tgtttcttca agaaccaatt ttccgtctgc
    42661 ccaggcagag tcattaacac gtgcagcagt gaaatcacca acgccttgtg tacggataaa
    42721 tggcaagagg tctttgtaga tagcgaaaag ttgatcgtgc cctgcattgg ctacagatga
    42781 tactgtgaca aacttgtctt gaagggcaga aacgccacgt gtatcagaca agtcaagggc
    42841 acgagatagc cagtcaagca agtttttcac tgtaccaggg atagagaagt tgtagactgg
    42901 agagaaaatc cagatagcat ccgcaacgag aactgattca cgagcagcag ctacagctgg
    42961 atgtgttgga acttccaaat cttggctgaa gagaggaagg gctgaataat caaggtagct
    43021 aacttccgct ttaccagcaa gtgctttctc agcttcgagc gccatttggt ggttgaaaga
    43081 accttgacgt agtgatccga cgataaataa tactttttta gacatgatgt gtctcctttt
    43141 tcttaaaatt tcgagaactc tctcgttgtt ataaaatata ttacaacaaa acaaaagaac
    43201 ttgcaagaaa tttgctcaga gtttatttga aaattgtaaa atttcggaaa ctctagtcat
    43261 ttgtgactga aaaagtaaga actgtttcac tttcaaaatc ggttttgttt gaagggagaa
    43321 atagaattgg ttgctcaaag cacagctttg aggttgcaga taaagctgac gtggtttgaa
    43381 gagattttcg aagagtattc ttatattcac ttgtaataaa gcttaataga tggtaaaata
    43441 gacgagtgaa aaaaagacaa aacaaagcaa aaaataatct actgtggcag tatggtctag
    43501 ggatgacgat tttgtttgtg gttatcagtg cttcctttct gtatatggtt tctcttagca
    43561 tgaaacccta tcaaacagct aaaagtgaag gagaaaaatt agctcagcag tatgcaggat
    43621 tagagcaggc tgatcaggtt gatttataca atggcttgga atcttattac agcgttcttg
    43681 gtcgtaataa acagcaagaa gcgcttgctg tcctgattgg taaagatgac cataagattt
    43741 acgtttatca gctaaatcag ggtatttcac aagaaaaagc agaaacggtt tctaaggaaa
    43801 agggagctgg cgagattgac aagataacct ttggtcgtta tcaagacaag ccaatctggg
    43861 aagttaagtc aggatctgat ttttatctag tagattttga aacaggagca ttggtcaaca
    43921 aggagggcct atgaaattat ccaaccgtgt tttagaaatg gaagaaagtg tgactttggc
    43981 tgctggagcc cgtgccaaag cactgaaggc tgagggtaga gatattttgt ctctaacctt
    44041 gggtgagcca gatttcacta ctcccaaaaa tatccaagat gccgccattg catcgattcg
    44101 agatgggcgt gcttcttttt atacagtaac ctcaggtctg ccagagctta aggcggtggt
    44161 caatagctac tttgagcgct tttacggcta ttctgtagcg tcaaatcaag tgacagtcgc
    44221 tgcgggagcc aaatattctc tctatacctt ctttatggct gtggtcaatc caggtgatga
    44281 agtcatcatc ccaaccccat actgggttag ctatggagat caggtcaaga tggcagaagg
    44341 cgttcccgtc tttgtttctg ctaaggaaga caatcacttt aaggtgaccg tagagcagtt
    44401 agaagcagct tgcactgaca agaccaaggt tttggtgctg aattcgccat ctaatcccac
    44461 aggtatgatt tacacccgtg aggaactctt ggcaattgga aactgggctg tagaaaatga
    44521 tattctcatc ctagcagacg atatctatgg ccgcttggtt tataatggtc atgagttcac
    44581 accgatttct agcctatcgg aagcgattcg caagcaaaca gtggtcatca atggtgtgtc
    44641 taaaacctat gccatgactg gttggcggat tggttatgcc gttggggaag cagacattat
    44701 cgctgccatg tccaagattg caggtcaaac aacttcgaat ccgtcagcag tagcccaata
    44761 tgcagcagtt gaggctctat caggtgagca agatactgta gaaagcatgc gtcaggcctt
    44821 tgaggaacgt cttaatacca tctatcccct ccttgcagaa gtgccaggat ttgaagtggt
    44881 caaaccgcaa ggggccttct atctcttccc aaatgtcaaa aaggccatgg agatgaaagg
    44941 ctacacggat gtgacagact ttacaactgt tatcttagaa gaagccgaag tggccttggt
    45001 aacaggagct ggatttggag caccagaaaa tgtccgcctc agctatgcga cagacctaga
    45061 cacgcttaaa gaagcagtcg aacgcttgaa agcatttatg ggtagtgaga atgattgatc
    45121 attttgagat taaggtaaag gatttacaaa tttcaggagg attttatagg agttttctcg
    45181 ctcctttgga ctataaattg gcttttaaga ctagttctct aattagtttt ctatccccga
    45241 acagccctca tcctggtggt gatttttggc tgactcaagg aacacaagat cctgttcatt
    45301 ttgctttttt agcagaaaat aaggaagaag tttaggcttg ttatgaggct ggcttagagg
    45361 caggtgggcg agacaatggg gctcctggtt atcgaagtga gcgtccgatt tactatgctg
    45421 cttttatgat tgacctggat gggaacaata tagaggtggt ttgccataaa gaataaaaaa
    45481 gaaaaggaaa aataatgaca aaacgtgtaa cgattattga cgtaaaagac tatgttggtc
    45541 aggaagtgac gattggcgct tgggttgcca acaaatcagg aaaagggaaa atcgctttct
    45601 tacaattgcg tgatggaaca gccttctttc aaggtgtggc ttttaaacca aactttgtcg
    45661 aaaaatttgg tgaagaagtg ggacttgaga agtttgatgt tatcaaacgc ttgagccaag
    45721 aaacgtctgt ttatgtgaca ggtattgtca aagaggacga acgttctaaa tttggctatg
    45781 agttggacat cacagacatc gaagtgatcg gtgaatctca agactaccca atcacaccaa
    45841 aagaacacgg aacagacttt ttgatggata accgtcactt gtggctacgc tctcgtaagc
    45901 aagtagctgt gttgcaaatc cgtaacgcta ttatctatgc aacttatgag ttctttgaca
    45961 agaacggttt tatgaagttt gacagcccaa ttctttcagg aaatgcggca gaagattcta
    46021 cagaactctt tgaaactgac tacttcggaa cgccagccta cttgagccaa tcaggtcagc
    46081 tttacctaga agcaggggct atggctcttg gtcgtgtctt tgactttggt ccagttttcc
    46141 gtgctgaaaa atcaaaaaca cgccgtcact tgactgagtt ctggatgatg gatgctgagt
    46201 actcatactt gacacatgat gagtcgcttg acttgcaaga agcttatgtg aaagctcttc
    46261 tacaaggtgt tcttgaccgc gcgcctcaag ccttggaaac cttggaacgt gatacagaac
    46321 tcttgaaacg ctacattgca gagccattca aacgtatcac ttacgatcaa gccattgacc
    46381 tcttgcaaga gcatgaaaat gatgaagatg ctgactacga gcatcttgag catggtgatg
    46441 actttgggtc accacacgaa acttggattt caaaccactt tggtgtgcca acatttgtca
    46501 tgaactatcc agcagccatc aaggccttct acatgaaacc agttcctgga aatccagagc
    46561 gcgtgctttg tgcagacttg cttgctccag aaggctatgg agaaattatc ggtgggtcta
    46621 tgcgtgagga agattacgat gcccttgtcg ctaagatgga tgaacttggc atggatcgta
    46681 cagaatatga attctacctt gaccttcgta aatacggtac agttccacac ggaggatttg
    46741 gtatcggtat cgaacgtatg gtaaccttcg cagcaggaac aaaacatatc cgtgaagcta
    46801 ttccattccc acgtatgttg caccgtatca aaccataaga acaggaaaac gcccatgtgg
    46861 cgttttttcg aattctagtg tttttacttg cgtaaaaaaa ttttttctag tataatagtt
    46921 tattgtgagc gaacctcact taccccttgc aaagtcttgg ggtcattaga ccaaaaggag
    46981 gaacatatca atggctaaat acgaaattct ttatatcatt cgtccaaaca ttgaagaaga
    47041 agctaaaaac gctttggtag cacgttttga ctctattttg actgacaacg gtgcaactgt
    47101 tgttgaatca aaaacttggg aaaaacgtcg tcttgcatac gaaatccaag atttccgtga
    47161 aggactttac cacatcgtta acgttgaagc aaatgacgat gcagctctta aagagtttga
    47221 ccgtctttca aaaatcaacg ctgacattct tcgtcacatg atcgtcaaaa ttgacgcgta
    47281 agaaggtaaa ctatgattaa caatgttgta cttgtagggc gtatgacacg tgacgctgaa
    47341 ttgcgttata ccccatcaaa tgtagcagtt gcgactttta ctcttgcagt aaaccgtaca
    47401 tttaagagtc aaaatggtga acgtgaggct gattttatca atgtcgttat gtggcgccaa
    47461 caggctgaaa atcttgctaa ctgggctaaa aaaggctcac ttatcggggt gacaggtcgt
    47521 atccagactc gtagttacga taaccagcaa ggacaacgtg tctacgtgac agaggtcgtg
    47581 gctgagaatt tccaaatgtt ggaaagccgt agtgtgcgtg agggtcacac aggtggagct
    47641 tactctgcac caactgcaaa ctattcagca cctacaaatt cagtaccaga cttttcacgt
    47701 aatgaaaatc catttggagc aacaaaccca ttggatattt cagatgatga tttaccattc
    47761 taatggacaa ctaaatttat aaaggagaaa aaacatggct caacaacgtc gtggcggatt
    47821 caaacgccgt aaaaaagttg attacatcgc agcaaacaaa attgaatatg ttgattacaa
    47881 agatactgag cttcttagcc gtttcgtttc agaacgtggg aaaatccttc ctcgtcgtgt
    47941 aacaggaact tcagctaaaa accaacgtaa agtaacaaca gctatcaaac gcgctcgcgt
    48001 aatggctttg atgcctttcg taaacgaaga ttaaagaaaa gacccagttg ggtctctttt
    48061 tcatgagctt gaaaacaaga aagcgaatta agaccccaac gggtcttttt tcacaagctt
    48121 tgaaatgaga gagcgagtta ggctcagtgg ctcccttttt acgagtttga aaacaagaga
    48181 acacattaaa agcacgatgg agctttttca taaatatgtc tcttttctca tccaagaaat
    48241 taaaataaaa atgataaact ttttgaaaat aggggatttg cctactttat gatataatgg
    48301 aaagagttag attgaaagag gtagtgagat ggacgcgaaa ttaagataca aggcaaagaa
    48361 gatcaagatt gtcttttttg atattgatga tacattgcgg aattcaaaga cagggtttat
    48421 tccaactaca attcccactg tttttaaaca gttgcgtgaa aaaggaattt taacaggaat
    48481 cgcctctgga cgtggcattt ttggtgttgt tccagagatt cgtgatctca agcctgactt
    48541 ttttgtaact ttgaatgggg cttatatcga agataaaaaa ggtcaggtca tttatcagca
    48601 tcagattgaa aagtcagatg ttgaggagta tatctcttgg gctaagcaag aaggaattga
    48661 gtatggcttg gttgggagtc atgatgccaa gttgtcgact cgcaccgata tgatgagtga
    48721 agctatcaat ccaatttatc ccgacttaga tgtagatccc gatttccatg aaaaagaaga
    48781 tatctatcag atgtggactt ttgaagataa gggagatgac ttgcacttgc ctgacagtct
    48841 ctcagacaaa cttcgcatgg ttcgttggca tcaacattcg tctgatattg tgccgatttc
    48901 aggctccaaa gcgacggggg tggaaaaggt tgtggaacac cttggcttga aaccagagaa
    48961 ggtcatggtt tttggagatg gtctcaacga cttggaactc tttgattatg ctggaatcag
    49021 cgttgccatg ggaatttctc atgataaaat caaagaaaaa gcagattata ttacaaaaac
    49081 attagaagaa gatggcattt ttgctgcctt agaagtattt ggtatggtag aaaaagaatt
    49141 gcattttcca caagtagaca ttgaaacagt agaaggtcct cttgcgacta ttaagaccaa
    49201 tcacggagac ttacgtatca agcttttccc tgaacatgct cctaaaacag tggctaactt
    49261 tgtatctctt tcaaaagatg gctactatga tggtgtcatt ttccaccgta ttatcaagga
    49321 ctttatgatc caaggtggag acccaactgg aactggtatg ggtggccagt caatctacgg
    49381 cgaatctttt gaggatgaat tctcagaaga gctttacaat atccgtggtg ctctttccat
    49441 ggcaaatgct ggtccaaata ccaacggcag ccagttcttt atcgtgcaaa accaacacct
    49501 accttattct aagaaagaaa ttactcgtgg tggttggcca gaaccgattg cagaaatcta
    49561 tgccaatcaa ggtgggacac ctcacctaga ccgccgtcac acggtttttg gtcagttagc
    49621 tgatgaagca tcttacgctg tcttggatgc cattgctgct gttgagacag gagctatgga
    49681 caagccagtt gaagatgttg taattgaaac tattgaaatc gaggactaag atgaaaatcg
    49741 gtgataagct aaaggggcgt attacaggga ttcagcccta cggtgccttt gttgagttag
    49801 agacgggtga tacggggctg attcacattt cagaaattcg gacaggattt attgaaaata
    49861 ttcatgaaac cttgaaagtc gatgaagagg ttcaagttca ggtagtggat ttagatgaat
    49921 ttacggggaa agccagtctt tctatccgca ctttggagga agaaaagtac cagtttccta
    49981 gacggagacg cttttcaagc gaccgcttta actacggttt tgctcccttt cgacgaatgc
    50041 taccaatctg gactggagaa gccctgcacc atttaaaaaa gaagaagtag tttagagttt
    50101 tatatttttt gtaatgttaa tatgaatttg ctataatagg accatggaag aagaacaatt
    50161 attaaaatca ggagagcgca ttaaccagct cttttcgaca gatatcaaaa tcattcaaaa
    50221 tagagaggtt tttagctatt cggtggatag tgttctctta tcacgatttc cacgttttcc
    50281 taagaagggg ttgattgtgg atttctgtgc tgggaatgga gcagtggggc tttttgctag
    50341 cactcgtact caagcacaga tattgtctgt tgagattcag gagcgtttgg cggatatggc
    50401 tgaacgctct gtccgtttga atggattaga ggagcaaatg caggtcatct gcgatgattt
    50461 gaaaaatatg cctgctcaca ttcaggggag taaggtggat atgattttgt gtaatccacc
    50521 ctatttcaag gtggatcctt attctaatct gaacgagagt gaacattatc tcttggctcg
    50581 acacgaaatc acgactaatt tggaagaaat ctgtcgtagt gcccagagta ttctcaagtc
    50641 taatgggcgt ttggccatgg ttcatcgtcc tgatcgactt ctggatattt tggatacgtt
    50701 aaaacgacat aatctagccc ctaagcgcct gcagtttgtt tatccaaaaa gagaaaagga
    50761 agccaatatg cttttgattg aggcgatcaa ggatggctca acaagtggct ttaaggtctt
    50821 acctcctttg attgtccaca atgatgatgg ctcttatacg cccgaaatcg aagagattta
    50881 ttatggatca taaggcttat atgtacgttc tggagtgtcg tgatggatcc tactatatag
    50941 gctatacgac tgatatgaga agacgcctcg ctatccacaa tagtgggaag ggagccaaat
    51001 atacacgagc acgcttgcca gtcaaactta tctatgctca aggttttgcc agtaaggaag
    51061 aagccatgtc ggctgaagct cttctcaagc gtaagaagag gccacagaag gaagaatttt
    51121 tatctgaaaa tcaagataga aatttactca gttattttga agaatcgtgg ggagtccttt
    51181 gactcctctt acctttgtca aaaagcgaaa aaaatgctac aataaagaaa ataaacaaaa
    51241 tgaggtatta tcatgtccaa gattctagta tttggtcacc aaaatccaga ctcagatgcc
    51301 atcggatcat ctgtagcttt tgcctacctt gcaaaagaag cttacggttt ggatacggaa
    51361 gctgttgccc ttggaactcc aaatgaagaa acagcctttg tcttgaacta ttttggtgtg
    51421 gaagcaccac gtgttatcac ttctgccaaa gcagaggggg cagagcaagt tatcttgact
    51481 gaccacaatg aattccaaca atctgtatca gatatcgctg aagtagaagt ttacggtgtt
    51541 gtagaccacc accgtgtggc taactttgaa actgcaagcc cactttacat gcgtttggag
    51601 ccagttggat cagcgtcttc aatcgtttac cgtatgttca aagaacatgg tgtagctgtg
    51661 cctaaagaga ttgcaggttt gatgctttca ggtttgattt cagataccct tcttttgaaa
    51721 tcaccaacaa cacacccaac agataaaatc attgctcctg aattggctga attggctggt
    51781 gtgaacttgg aagaatatgg tttggcaatg ttgaaagctg gtaccaactt ggctagcaaa
    51841 tctgctgaag aattgattga tatcgatgct aagacttttg aactcaacgg aaataatgtc
    51901 cgtgttgccc aagtgaacac agttgacatc gctgaagttt tggaacgcca agcagaaatt
    51961 gaagctgcaa tgcaagctgc caacgaatca aacggctact ctgactttgt cttgatgatt
    52021 acagatatcg tcaactcaaa ctcagaaatc ttggctcttg gtgccaatat ggacaaggtc
    52081 gaagcggctt tcaacttcaa acttgaaaac aatcatgcct tccttgctgg tgccgtttca
    52141 cgtaagaaac aagtggtacc tcaattgact gaaagcttta atgcgtaaga ttttgggtgt
    52201 cagctcaaaa tcggaaagtc tagtttgcct tatatcgaaa ggagtttcgg ctcctttttt
    52261 ctaggagtga agtatgttag aaaatggcga tttgattttt gtgagagatg ggtcagacat
    52321 gggacaggcc atccagactt ccacaggtaa ctatagccat gttgccattt atttggatgg
    52381 gatgatttat catgctagtg gacaggctgg tgttgtctgt caagaaccgg cagacttctt
    52441 tgagtccaat catttatacg acctctatgt ttacccagaa atggatatcc agtcggtgaa
    52501 ggaaagagct tgcaaacatc ttggagcacc ctacaatgct tctttctatc cagatgcagc
    52561 tggtttttac tgctcccagt atatagcaga aatcctacct atttttgaaa ctattcctat
    52621 gaaatttgga gatggggagc aggagattag tgatttttgg agggagtatt acatagaact
    52681 aggtctgcct gttcctctga accaagctgg taccaatcct agtcagttgg cagcatcgcc
    52741 tctgttacaa tgtaaagaaa ggaatcttca tgattcagat ttttaattca tctcgtttga
    52801 cgagacagcc atttttggag aattgatccg ctatctggat cagtatgagg atgtgattct
    52861 acgggaaatt aaggctcaat ttccagatgt tgcagttgat aaactcatgg aagagtatat
    52921 aaaggcaggc ttgattctac gtgaaaataa gcgctattac ctcaattttc ctacgcttga
    52981 atcacttgat agtcttgaac tggatcaaga gatttttgtc agagaagcta gtccggtcta
    53041 tcaagccttg ttggagcaga gttttgagac ggaattgcgc aatcaaatca atgcagctat
    53101 tttagttgaa aagacggact ttgcgcgcat taaaatgacc ctgtccaatt atttttacaa
    53161 ggtcaaacag cagtatcctt tgacagaaaa acagcaggag ctctatgaca ttttaggaga
    53221 tgttaatcct gagtatgccc tcaagtatat gacggctttt ttgttgaaat ttctcaaaaa
    53281 agaccagctt atgcagaaat gccgtgatat ctttgtggac agttaggttg tcttaggcta
    53341 tattgtgcaa aatgaagatg gaaagtatga gttggctatc gattttgata aggagaggtt
    53401 aactttctac ttagcgtgat ttcttgtttc tgagtacatt gtttgacttt ccttagtatt
    53461 cggtataaac tatatgtaac cggtaacaca tatcggaata aactaaagga gacaatcata
    53521 tgtcacttga aaacaaattg gaacaagcaa caggcgctgt caaagaaggt tttggtaaag
    53581 ttactggaga cagcaagaca gaacttgaag gagctgttga aaaaacagtt tctaaggcaa
    53641 aagacgttgt agaagacgca aaaggtgctg tagaaggtgc cgttgaaggt ttgaaaaacg
    53701 tttttactaa ataataggaa aaaatcaagg gtttcatttt cccttgattt tttctattct
    53761 tataaataat tttctgcgac ggctgtatct cctgggtagg attctttctt gccctggatg
    53821 atttggtaac aatcggctcc cttacccgca ataataactg catctaattc gtgatttgtg
    53881 atagccattg ccgccttgat ggcttcttgg cgatccgcaa tcttctcaac aggatgattg
    53941 atgtagctac taatttcatc tgcaatggcc attgggtctt catagttagg gtcatcagca
    54001 gtcagaaaga cttgaatctc agggtgttga ttgaggagga ggccaaagtc cttacgacga
    54061 ctttctccct tgtttcctgt tgatcccaga accagagcaa tctttccggt ttgatgagtt
    54121 tcaaccacat tgatgagttt tttcagacta tccccattgt gggcatagtc gatgaagacc
    54181 ttggctccat ttttctgagt gaggacttcc atacgaccag gaacgcgggt tgcagcgatg
    54241 ccttttttga tgtcctcaag acttgctccg agacggagac aagcaagtcc agcagcaact
    54301 gcattttctt ggttgaagtt gccaatgagt tggatatcat aatctccagc gagtttaccc
    54361 gtagctgaaa atctaaaggc tttggaattc tcgatttggt tatcaaattg gctaccatag
    54421 aaatcatggt cttgatcttc aacctgttct ttcaagactg agaagtggtc catgtcactg
    54481 ttaatgatga ctgctcggct attttccatc aagagacgct tgtggtagaa atagtcttca
    54541 aagctagggt gttcaatcgg gccgatatgg tctaggctga tatttaggaa aactcccaca
    54601 tcaaaggtta gaccatagac acgtttgacc agataggctt gactggagac ttccatgatg
    54661 aggtgggtac ggtcattttg cacagcctga ttcatcatgt caaagaggtc aatactctca
    54721 ggggttgtca acgctgactt aaagaaagtc tctccatcaa gagttgtgtt catggtcgac
    54781 aacatagcag gtcgatgccc ttgagataag atgttatagg cgaaataggc tgctgttgtc
    54841 ttacccttag taccagtaaa ggcaaggagt ttgagttttt cctgtggatt accatagaac
    54901 tccatggcaa tcaaactcat ggctttcttt atatcgttca caatgatgac agggataccg
    54961 acttcgtagt ccttttcagc tatataccaa gctaagcctt gtgttatagc agaaagaagg
    55021 tattcttttt taaaggcagc gccttttgca aaaaaaagag tgtcttctgt tacttttcgg
    55081 ctgtcgtagc tgatgctatc aaaaacaact ttgctgtagt tgtagtggta atgaccttgg
    55141 tcaataattt cgcgaaaaag gccatctttc tttaaaatat ctaatacagt ttcaattttt
    55201 atcatacttt ctattgtaaa ccgaaagtcg caaatttaca agtgacaagg aaaagtttat
    55261 aatggaagat aaggagtttt tcctagttat caaaattgaa tgaggaatct atgtcgcacg
    55321 aaaacaatca ccagcaggcc cagatgttac gggggactgc ttggctaacg gctagtaact
    55381 ttatcagtcg cctactcggg gctgtttaca ttatcccttg gtacatctgg atgggggctt
    55441 atgcagctaa ggcaaatggt ctctttacca tgggttacaa tatctatgct tggttcttgt
    55501 tggtttcaac agcggggatt ccagttgcgg tggccaagca agttgccaag tataatacca
    55561 tgcgagaaga agagcatagc tttgccctga ttcggagctt cttaggcttt atgacaggac
    55621 taggcctggt ttttgcttta gtcttgtatg tctttgctcc ttggctagca gacttgtctg
    55681 gcgtgggcaa agacttgatc ccaatcatgc aaagcttggc ttggggagtc ttgattttcc
    55741 cgtctatgag tgttatccga ggatttttcc aagggatgaa taacctcaaa ccctatgcca
    55801 tgagccaaat tgctgagcag gtcattcgtg ttatctggat gctcctagca acctttatca
    55861 ttatgaagct cggttcagga gattatctag cagccgttac ccaatcaacc tttgctgcct
    55921 ttgtcggtat ggtagccagt tttgcagtct tgatttattt ccttgcccaa gaaggttcac
    55981 tcaaaagagt ctttgaaaca ggagataaga ttaacagtaa gcgtctcttg gttgatacca
    56041 ttaaggaagc cattcctttt atcctgacag ggtctgccat ccagctcttc cagattttgg
    56101 atcagctgac ctttatcaat agtatgagct ggtttaccaa ctacagcaat gaggacttgg
    56161 ttgtcatgtt ttcttatttc tcagccaatc ctaataaaat cacgatgatt ttgatttctg
    56221 taggggtttc gattgggagt gttggtttgc cacttttgac ggaaaactat gtcaaggggg
    56281 acttgaaagc agcttctcgt ctcgttcagg acagtctcac cctactcttt atgttcttgc
    56341 taccagcaac agttggagtg gttatggtag gagaacctct ttatacggtc ttctatggta
    56401 agccagatag tttggctctg ggcttatttg tctttgcagt tttgcagtct attattttag
    56461 gcttgtacat ggtcttgtct ccaatgcttc aggccatgtt ccgcaaccgc aaggccgttc
    56521 tctattttat ctatggttct attgccaagc tagtcttgca actacctacc atcgccctct
    56581 tccacagtta tggtcctttg atttcaacaa ccattgctct catcattcct aacgtcttga
    56641 tgtatcggga tatttgtaaa gtaactggtg tcaagcgcaa ggtgattttg aagcgaacca
    56701 ttttaatcag tttgctgacc ctagtcatgt ttctgttaat aggaaccatc cagtggctgt
    56761 taggattttt cttccaacca agtggacgtt tgtggagctt cttttatgta gctcttgtcg
    56821 gtgccatggg gggtggactt tatatggtta tgagtctgcg tacctatttg ttagataagg
    56881 taataggaaa agcccaagca gatcgcctgc gagcaaaatt taagctttcg taaggtagca
    56941 tttataaata aaaggaataa gttgaacaat cttttaggag aacttgaaac ttattccttt
    57001 tttagcgtaa aaatagctaa aattatcttt caaaaataga aaatgaggtt tttttcgatt
    57061 ttttggaaaa ataattgact aaacaaacca aacgttgtat aataaaacaa atatttaaag
    57121 caggaggttc tggaaatgaa aaagtctaag agcaaatatc taaccttggc aggtcttgtc
    57181 ctgggtacag gagttttatt gagcgcgtgt ggaaattcta gcacggcgtc aaaaacctac
    57241 aactatgttt attcaagtga tccatctagc ttgaactatc tagcagaaaa ccgcgcagca
    57301 acatccgata ttgttgcaaa tttggtagac gggttattag aaaatgacca atatgggaat
    57361 attattccat cattagcaga ggattggact gtttctcagg acggtttgac ctatacctac
    57421 aaacttcgta aggatgccaa gtggtttact tctgagggag aagaatatgc gcctgtaact
    57481 gcccaggatt ttgtgacagg tttgcaatat gcagctgata aaaaatcaga agccttgtat
    57541 ctagtgcagg actctgttgc tggtttggat gactatatca ctggtaaaac aagcgacttt
    57601 tcaactgtcg gtgtcaaggc acttgatgac caaacggttc aatatacttt ggttaaacca
    57661 gaactttact ggaattcaaa aacacttgca acgatacttt ttcctgttaa tgcagatttc
    57721 ctgaaatcaa aaggggatga ttttgggaag gcggatccat ctagtatttt gtacaatgga
    57781 cctttcttga tgaaagcact tgtctcaaaa tctgctattg aatataagaa aaaccctaat
    57841 tactgggatg ctaagaatgt ctttgtagac gatgtgaaat tgacctacta tgatggtagc
    57901 gaccaagaat cactggaacg taattttaca gctggtgctt atactacggc tcgtcttttt
    57961 cctaacagct ccagctatga agggattaaa gaaaaataca aaaacaatat catatatagt
    58021 atgcaaaatt caacttcata tttctttaat tttaacctag ataggaagtc ttacaattat
    58081 acttctaaaa caagtgacat tgaaaagaaa tcgactcagg aagcagttct caataaaaac
    58141 ttccgtcagg ctatcaattt tgcttttgac agaacatctt atggggctca gtctgaaggg
    58201 aaagaaggtg caacaaagat tttgcgtaac ctagtggttc ctccaaactt tgtcagtatc
    58261 aagggaaaag actttggtga agttgtagcc tctaagatgg tcaactatgg taaggaatgg
    58321 caaggtatca actttgcgga tggtcaagac ccttactaca atcctgagaa atccaaggct
    58381 aagtttgcgg aagctaagaa agaactcgaa gcaaagggtg ttcaattccc aatccacttg
    58441 gataagactg tggaagtaac agataaagta ggcatacaag gagttagttc tatcaaacaa
    58501 tcaattgaat ctgttttagg ttctgataat gtagtgattg acattcagca attaacatca
    58561 gatgagtttg acagttcagg ctactttgct caaacagctg ctcagaaaga ctatgattta
    58621 tatcatggcg gttggggacc tgattatcaa gacccgtcaa cctatctcga tatttttaat
    58681 actaatagtg gaggagttct acaaaatctt ggactagagc ctggagaagc caatgacaag
    58741 gctaaggaag ttggactgga tgtctatact caaatgttgg aagaagctaa taaagagcaa
    58801 gatccagcca aacgttatga gaaatatgct gatattcaag cttggttgat tgatagttct
    58861 ttagttcttc caagtgtttc gcgtggggga acaccatcat tgagaagaac cgtaccattt
    58921 gctgctgcct atggtttaac cggtacaaaa gggattgaat catataaata cctcaaagta
    58981 caagataaga ttgtcacaac agacgaatat gcaaaagcta gagaaaaatg gttgaaagaa
    59041 aaagaagaat ccaataaaaa agcccaagaa gaattggcaa aacatgtcaa ataaaatcta
    59101 attgtagata agtttgtgta agaagtcttt gtgcttaaaa acgcataata tcaggtatat
    59161 aaaatcctag atgttatgcg ttttgttata ggaagattta ttagatttta tcctcaaatt
    59221 gagttattcc cgactttatc cgttgaaata ttataaggag tatttatgaa attaaaatta
    59281 ttaagagtag atactaaggt gattatgggg agtttcttcc ttgttctgtc tagtctactt
    59341 gctttgttgc ttccccttat cttaaaaggt ttaatagatg ggagttctat tgaaaatata
    59401 ggttccaaag tatttcaatc gtttttgatt tttattggtc aagccttgtt ttcttctatt
    59461 ggttactatc tgtttagtca atcgggtgaa aaaaagatag caaaaatcag gaaaaaagtg
    59521 atagaggggt tgatttatgc agagaaatcc ttctttgata agagccaaag tggggagttg
    59581 acttctgcca ttgtcaatga catgagtgtc attcgtgagt ttttaattac gactttccca
    59641 aatattattc tgagtttagt tatggtactt ggttccattg tagtcttatt tagtcttgat
    59701 tggaatcttt ctctactttt attcatcact cttccttgta tgatgtttat tatcttgccc
    59761 ctttccaata tcagtgaaaa gtatagtcgt cgtttacagg aggaaatcgg atttttaaca
    59821 gggcaattga ctgaaaagat tcaagaacat gaattaatta agactaacca agcagagaaa
    59881 agtgtacagg atgttttgga taattgtatt gaaagggtac aaaacaattc actgaaatca
    59941 gatagggtta cttcttttga gaccccgttt gctctcttat ttatctttgc gactatagct
    60001 gtgatgctaa cctatggggg ttatcgggtc agcgcaggat atatatctgt gggaaccttg
    60061 gtttcgtttt tgatttacct ctttcaatta cttaatccta ttagtaatat agctaatttt
    60121 gtaactgttt attctaggag caagggatct tcagttgcac tggagaactt gcttgcagtt
    60181 cctaaagaaa aatttgaggg aggaaaatcg gtatcaggat aaaggttgaa ttttaaccat
    60241 gtctattttg gttatgatga aaatcgacct gtcttaaagg atattacttg ttcaattttc
    60301 aaggggaaaa aaattgcttt tgttggacca tctggatcag gaaaatcaac gattgtgcgt
    60361 ttgttagagc ggttttataa accgctttca ggagatattc taatggagca atcaagtata
    60421 tatgatttta acttaaaaga atggagaagt aaaatcgctt gggtttcaca aaataatgca
    60481 gtcttatctg gcagtattcg tgacaatctt tgtctcggtt tgaatcgctt agtaactgat
    60541 gatgaattga tgaaagtgct agacttagta tcactaggtg atgagattcg ctccatgaaa
    60601 gagggactag atactgaagt tggtgaacgc ggacgattct tgtcaggggg gcaaagccaa
    60661 agacttcaaa tagctagagc ctacttaaaa gatgctgaaa ttcttatatt tgatgaagcc
    60721 actgctaatc ttgatgcgga ttctgagtat gcgattatca gtagcctcta ttctgtatta
    60781 aaggagaaga cggttgtgat tatagcgcat agtttgtcaa cggtaaaaga tgtggattgt
    60841 attttcttct tagaggaggg gaaaatcact ggctcaggaa ctcataagga actactggaa
    60901 aatcatgagc gttatgctcg ttttgtgcag gagcaaatga tagagtgaag tgtcttttga
    60961 gattcaccat tttatagtct attaaaggga gcaggaaaaa ctcccttttt atatagtttg
    61021 aaactataac tagctcttga aaagaagaaa atgagttgat gaaaataagt ggtacaatag
    61081 ttactataga tttggaggta ttgtatgagc aaggaattac acattaacac aattttggcc
    61141 caggcgggta ttaagtcaga tgaagcgaca ggtgcattgg tgacaccgct tcatttttca
    61201 acgacctatc agcatccaga gtttggtcga tctactgggt ttgactatac gcgcactaaa
    61261 aatccaactc gtagtaaggc tgaggaagtc ttggcggcta ttgagtcagc agactatgcc
    61321 ctagcgacta gctcagggat gtcagctatt gtactggcct ttagcgtctt tccagtagga
    61381 agtaaggtct tggcagtgcg tgatctttac ggtggttctt ttcgctggtt taaccaagtg
    61441 gagcaggaag gtcatttcca ttttacctat gccaatacag aagaagagtt gattgccgag
    61501 ttagaaaagg atgtggatgt tctctatatc gaaaccccaa ccaatccctt gatgttggaa
    61561 tttgatatcg aaaaactagc aaaattggct catgctaagg gtgccaaagt ggtggtggac
    61621 aataccttct acagccctat ctaccaacgt ccgattgaag atggagcaga tatcgttctc
    61681 cattcagcaa ccaagtatct agcaggccac aatgatgtct tggctggagt ggttgtgacc
    61741 aatagtttag aactatacga gaagcttttt tacaatctca atacaacagg ggcagtcttg
    61801 tctccatttg acagctacca gttgcttcgt ggtctcaaga ctttgtctct tcgtatggag
    61861 cgctcaacag ctaacgccca agaagtggtt gcctttttga aggattctcc agcagttaag
    61921 gaagttctct acactggtcg tggaggcatg atttccttta aagtagccga tgaaacacgc
    61981 attcctcata ttttgaacag tctcaaggtc ttctcttttg cggaaagttt gggtggagtg
    62041 gaaagtctta ttacttatcc aacgactcaa actcatgctg atattccagc agaagtacgc
    62101 cattcttatg gtttgacaga tgacctcttg cgtttgtcta ttgggattga ggatgctaga
    62161 gatttgattg cagatttgcg ccaagcctta gaaggataag acaaagatgg gaaaatatga
    62221 ttttacaagc ctgcccaacc gtttagggca ccatacctat aaatggaaag aaacagaaac
    62281 ggatagtgaa gttctaccag cttggatagc ggatatggac tttgtggtct tgcctgaaat
    62341 ccgccaagcc gtgcaaactt acgcagacca actggtttat ggttatacct atgccagtga
    62401 agacttaatt aaggaagttc aaaagtggga agctacacaa tacggttaca actttgacaa
    62461 agaggctctt gtctttatcg agggtgtggt accagccatc tcaacagcta ttcaaacctt
    62521 tacaaaagaa ggcgaggcgg ttttaattaa cacgcctgtc tacccaccct ttgctcgcag
    62581 tatcaagttg aataatcgta gattgattac taattcctta gtggaaaagg atggtctgtt
    62641 tgagattgac tttgaccaac ttgaaaagga tttggtggaa gaggaggtta aactctatat
    62701 tctttgcaac cctcacaatc ctggtggacg tgtttgggaa aaagaagtgt tggagaagat
    62761 tggccaactc tgccaaaaac acggtgtttt gttagtttcg gatgagattc accaagattt
    62821 gaccctcttt ggtcacaaac accagtcttt caataccgtc aatcctgcct tcaaaaattt
    62881 tgctatcgtc ttgagcagtg ccactaaaac atttaatatt gctggaacaa aaaattccta
    62941 tgcagtcatt gaaaatccta agttgagact ggctttccag aaacgcctgt tggccaataa
    63001 tcagcatgaa atttcaggct tgggttattt ggcgacagaa gctgcctatc gatacggtaa
    63061 agattggcta gaggaactca agcaagtctt tgaagaccac atcaattatg tggtggatct
    63121 atttggaaaa gagactaaaa tcaaggtcat gaaaccgcaa ggtacctact tgatttggct
    63181 tgacttttca gcttatgacc tgactgatga aacattgcaa gagttgttga gaaatgaagc
    63241 caaggttatc ctcaaccgtg gtttggattt tggagaggaa ggaagtctcc atgcccgcat
    63301 caatatagct atgcccaaat ctctgttgca agaagtctgt cagcggattg tggctacttt
    63361 tgccaaacgt taaaaatcca gccttctagg agaaaagtct tcctagaagg ctattttcat
    63421 aggagaaaat atggtataat aaaaagataa ggtaaaggtg aaaatatggc taaattgatt
    63481 ccggggaaag ttcgtatcga aggtgttgcc ctttatgaaa ctggtaaggt tgatatcatc
    63541 aaggaaaaga acaatcggct ctacgctcgc gttgcagaag aagaactgcg ctatagttta
    63601 gaggatgatt tggttttttg tgcctgtgat ttttttcaaa agaggggcta ctgtgtgcat
    63661 ttggcagcgc tagagcattt tctgaaaaat gatgagcgtg gtcaggaaat cttgtggagt
    63721 ctggaagaag gtcatgaaga aaaagaggct gttgaaacca aggtgacctt gggtggcaag
    63781 tttttggatc gaattttatc tccaaaatca gaatgcgcct atgagttatc agctgtgggt
    63841 caggtggaag caggaaccaa tcatatcttg tggactctga gaatcggcca aatcaatagc
    63901 caaaaatact atgtcattcg ggatattcca ctttttttaa ggattgtcga gcagagaaag
    63961 tcgtatatga ttggcaagat ttatgaggag tctctttctt gggaagcctt tgatgatgcc
    64021 agccaagaac ttttgacttt cttgcacgga ctaacggagg aagggctggt tccagacctc
    64081 tttttccaaa accaaggtcg gcacctcttt ttccctctga ccttttttga gcagggtgtg
    64141 aatttactga tggccttgcc ccattttcaa tttgaccatc aagtggatag ctaccaaacc
    64201 ctgctttttc aggatatgca tgctgatgcc aatctatttg cctttacagt aacagaatac
    64261 tcggattatt ttgaaatgga aatcagtgag agtcctaggg ttaatgtctt ttatcaggga
    64321 gcagtacttt tccataaagg tcaggtttat tttttaacag accagcagat gcgtcttctc
    64381 aaggaaatta aagtgttacc tgtgggtcaa caaggaaaga aatacttgca atttgatagc
    64441 agtgatcgag acaaattggc ctcctgtctg actcttttta tccagatggg caccgtttca
    64501 gctccagaac gtctacaaat caaaactttt gcgccctctt tttactttga cagggaaaaa
    64561 gataatcgga ttcgtttaga aattcagttt gattatggaa atagacaggt atctagccga
    64621 caagagctag aagaattacc attttcaagt gacgcggact tagaagaaag aattttccaa
    64681 gtctgtttgg ctgcgggctt tgaagccgat tttcaatctt ggcgtcaggc cttaaaagcg
    64741 gagtctgtct atcatttttt tcatgatatc attccagtct ttgaaaaact cgggcatgtt
    64801 gacctatcag ataaactaga agagctttat agcctagcga gtcctcaggt gcagattgcc
    64861 tccaagggag gtctcttgga aatccagttt gattttcaaa atattgccca ggaggaaatc
    64921 gaccaagcca tgcaggcctt ggttgccaat caggattttt atattgattc gtctaatcaa
    64981 gtttactttt tcgatgaaga aaccaagaaa attcggcaaa atctacagga actggggcaa
    65041 tttgaattaa aagatgggac cttgcaggct cggaaatcct tggcctacag tttagctcat
    65101 ctctttgaag ggcgagaccg tgtttctttt tcacaagaat tccagaatct ggcccaggat
    65161 ttgacacatc cagaggactt tcctcgacag gcaactcagg ttcaggctga cttgcgagat
    65221 tatcaggaaa agggaattgg ctggttgcag atgctccatc attatggttt tggtgggatt
    65281 ttggctgatg atatgggact tgggaaaacc cttcagacca ttgctttttt gactagtcaa
    65341 gtgacaaaag aaagtcgggt tttgattctc gctccgtcag gtttgattta caactgggca
    65401 gatgagtttc agaaatttgc cccacagttg gatgtggctg ttgttcatgg tttgaaagca
    65461 agtcgtgagg agattcttgc cgagagccat caaatctatg tgactagcta tgccaccttc
    65521 cgtcaggaca gtgagtttta tcaggggatg gcctttgact tccttttctt agatgaggct
    65581 caggtcatga aaaatgccca gaccaagatt gcccagacct tgagacaatt tgtggtgccg
    65641 tcggtctttg ccttgtcagg aactccgatt gaaaaccatc tgggtgagtt gtggtctatt
    65701 ttccaaatcg tcatgcccgg acttttgcca agcaagaaag aatttatgaa attgccagca
    65761 gagcgagtgg ctcagtttat caagcctttc gtgatgcgac gcaagaaaga agaagttctg
    65821 actgaattgc cagacttgat tgaggtggtt tataaaaatg aactggaaga ccagcaaaag
    65881 gctatttacc ttgcccagtt acaacagatg cgagaccatc tggctcaagt gtcagaacag
    65941 gaatttcagc gaagtcgtgt ggaaatttta tctggtttga tgcgcttgcg tcaaatatgt
    66001 gacactcctg ccctgtttat ggaagattat cagggagcca gcggcaaact agatagtctc
    66061 cgagacctac tggtacaggt ggcagacggc ggacaccgtg tcttgatttt ctctcagttc
    66121 aagggaatgt tggaaaaaat tgaacaagaa ctgccagact tgggcctgac atcctttaaa
    66181 attacgggtt caaccccagc caaggaaaga caagacatga ccaaggcctt taaccaagga
    66241 gaaagagatg cctttctgat ttccctcaag gctggtgggg tcggtctgaa cctgacaggt
    66301 gcagatacag tgatcttggt tgacctttgg tggaatcctg cggtggaagc gcaagccatt
    66361 ggccgtgccc atcggatggg tcaggaagaa acggttgagg tctatcgctt ggtgaccaag
    66421 ggaaccattg aagaaaaaat tcaggaactc caagaacaaa agaaacatct ggtgtcacaa
    66481 gtattggatg gtacagagtc acgtggtagt ctgaccctag cagaaattag agaaattttg
    66541 ggaatttctg aagccagcac ttgaaaaatc aagacaatac gctataatga agtgttgaaa
    66601 ggaaatagaa aatgaaacaa gaacgatttc cattggtgtc agatgacgag gtcatgttga
    66661 ctgaaatgcc agtcatgaat ctctatgatg agtctgatct gatcagtaat atcaagggtg
    66721 agtatcgaga taaaaattat ttagaatggg ctcctattac tgaagaaaaa ctagtaaaac
    66781 cgattgaaaa gcaagtcgaa aaacctaaaa aggctccttt aggggttaaa aaagaaggaa
    66841 agagctatgc ggaggtggcg cgtgaagaag cgcgtgcgga cttgaaaaag aaacgctctg
    66901 ctaactacct aactcaggat ttcagccttg cgagacgtca ttctcagccc agtctagtta
    66961 gacagggcaa tcaaccgaca actcctttcc aaaaggaaaa tcctggtgaa tttgtcaaat
    67021 atagccaaaa attgacccag tctcattata tcttggcgga agaagttcat tctatcccta
    67081 ccaagaatga agaagtgtca gcacctgctc caaagaaaaa caattatgat tttctaaaga
    67141 agagccaaat ctacaataaa aaaagtaaac aaacagaaca agaacgtcgg gttgcccaag
    67201 agttgaatct gaccagaatg acagaatagg ggagaaaaca tgtcaaagac atatcatttt
    67261 atcggaatta agggatcagg gatgagtgcc ttggccttga tgttgcacca gatggggcac
    67321 aaggttcagg gatcagatgt tgaaaagtac tactttaccc aacgcggtct tgagcaggca
    67381 ggaattacca ttcttccttt tgatgaaaag aatctagacg gtgatatgga aattatcgct
    67441 ggaaatgcct ttcgtccaga taacaacgtc gaaattgcct atgcggacca aaatggtatc
    67501 agctacaaac gttaccatga gtttctaggt agctttatgc gtgactttgt tagcatggga
    67561 gtagcaggag cacatggaaa aacttcaacg acaggtatgt tgtctcatgt cttgtctcac
    67621 attacagata ccagcttctt gattggagat gggacaggtc gtggttcggc taatgccaaa
    67681 tattttgtct ttgaatctga cgaatatgag cgtcacttca tgccttacca cccagaatac
    67741 tctattatca ccaacattga ctttgaccat ccagattatt tcacaagtct cgaggatgtt
    67801 ttcaatgcct ttaacgacta tgccaaacaa attaccaagg gtctttttgt ctatggtgaa
    67861 gatgctgaat tgcgtaagat tacgtctgat gcaccaattt attattatgg ttttgaagct
    67921 gaaggcaatg actttgtagc tagtgatctt cttcgttcaa caactggttc aaccttcacc
    67981 gttcatttcc gtggacaaaa cttggggcaa ttccacattc caacctttgg tcgtcacaat
    68041 atcatgaatg cgacagccgt tattggtctt ctttacacag caggatttga tttgaacttg
    68101 gtgcgtgagc acttgaaaac atttgccggt gttaaacgtc gtttcactga gaaaattgtc
    68161 aatgatacag tgattattga tgactttgcc catcatccaa cagaaattat tgcgaccttg
    68221 gatgcggctc gtcagaaata cccaagcaag gaaattgtag cagtctttca accgcatacc
    68281 tttacaagaa ccattgcctt gttggacgac tttgcccatg ctttaaacca agcagatgct
    68341 gtttatctag cgcaaattta tggctcggct cgtgaagtag atcatggtga cgttaaggta
    68401 gaagacctag ccaacaaaat caacaaaaaa caccaagtga ttactgttga aaatgtttct
    68461 ccgctcctag accatgacaa tgctgtttac gtctttatgg gagcaggaga catccaaacc
    68521 tatgaatact catttgagcg tctcttgtct aacttgacaa gcaatgttca ataggatgtt
    68581 cccatggaaa ttccaattaa gattattcag gcaagcaagt ctgatttgcc tgagataggg
    68641 gcacttcaga cctcgtcttt tccagctgaa aagcagcaac tttcccatat tttagaagaa
    68701 agtatccgta agtgtgcgga tacctttctt ctagctaggg atgaaaatca acttttaggc
    68761 tatattttat caagtcccca gtcagacaat ccgcaatgtc taaaagtaca ttctttagtc
    68821 atcgagtctg accatcagag acagggcctg ggaacacttc ttcttgcagc cttgaaagag
    68881 gtggcagttg agctggatta caaagtgatt cgtttggaga gtcctgatga gctgctttcc
    68941 tattttggaa tgaacggttt tgttgatgaa gaagaaactt tgctctatgc aactagccag
    69001 ggctatagta tgatttggtt taatcccttt tatctggagg aacaatgaaa atcagacaag
    69061 caagattaga agatttggat cggattgttg aacttgaatt tgaaaatttt tcggtcgaag
    69121 aagccattcc tccttctgtc tttgaagcac atttgagaga aattcagacc tcttttctgg
    69181 ttgctgaaaa agaaggaaga atcatgggtt atatcgaagg accagttgac ctgcaccgcc
    69241 atctgcaaga ccagtctttt acagaagaaa taaaagacta tagtcatgag cctggtggtt
    69301 atatctctgt gacctgtctg tctattgcca aggaggcaca gggactcgga ctgggtcaga
    69361 aattgctgac agccttgaaa gaagttgctc ttgaagatga gagagatggc attaatctaa
    69421 cctgtcatga ctatctcatc gcctattatg aaaaacatgg atttgtcaac gaaggccagt
    69481 cccagtcaac ctttgcaggg gaaacatggt atgatatggt ctgggaaatg aaaaaataag
    69541 ttaggaaaag tatcatagat tgcttttttt ggacttttaa gatataatat tatggattat
    69601 caacaaggag gaaaaacttt tgagtgaaaa gtcaagagaa gaagagaaat taagctttaa
    69661 agagcagatt ctgagagatt tagaaaaagt aaaaggctat gatgaagttc tgaaagaaga
    69721 tgaggcagta gttcgcactc ctgcaaatga accttcagct gaagaactca tggctgattc
    69781 cttgtcaacg gtagaggaga ttatgagaaa agctcctacc gtgcctactc acccaagtca
    69841 aggtgtacca gcttctccag cagatgagat tcaaagagaa actcctggtg ttccaagtca
    69901 tccaagtcaa gatgtacctt cttctccagc ggaagaaagt ggatcaagac caggtccagg
    69961 tcctgttaga cctaagaaac ttgaaagaga atacaatgaa accccaacaa gggtagctgt
    70021 ttcctatacg acggcagaga aaaaagcaga acaagcaggt ccagaaacac ctacgcctgc
    70081 tacagaaaca gtggatatca tcagagatac atcacgtcgt agccgtagag aaggagcaaa
    70141 acccgctaag cctaagaaag agaagaagtc acatgtgaaa gcttttgtga tttcattcct
    70201 tgtattcctt gccttgctct cagcaggtgg ttactttggt taccagtacg tgctagattc
    70261 cttattacct atcgatgcta attctaagaa atatgtgacg gttggaattc cagaaggttc
    70321 aaacgttcaa gaaatcggta cgacgcttga aaaagctggt ttggtaaagc atggtctgat
    70381 ttttagtttt tatgccaagt ataaaaatta taccgacttg aaagcaggtt actacaattt
    70441 gcaaaagagt atgagtacag aagacttact caaagagttg caaaaaggtg gaacagatga
    70501 accgcaagaa cctgtacttg cgactttgac aattccagaa ggttatacct tggatcagat
    70561 tgctcaagct gtgggtcaat tgcaaggtga cttcaaagag tctttgacag cggagacttt
    70621 cttggctaaa gttcaagatg agacgtttat cagtcaagca gtagcgaaat atcctacttt
    70681 actggaaagt ttgcctgtaa aagacagcgg tgcgcgttat cgtttggaag gatacctttt
    70741 cccagctaca tactctatca aggaaagcac aactattgag agcttgattg atgagatgtt
    70801 agctgctatg gataagaacc tatctcctta ctatagtact atcaaatcta aaaacttgac
    70861 tgtcaatgag ttgttgacca ttgcttcctt ggtcgaaaaa gaaggtgcca agacagaaga
    70921 tcgtaagctc attgcaggtg tattctacaa tcgtttgaat cgtgatatgc cacttcaaag
    70981 taatattgca atcttgtatg cccaaggaaa actggggcaa aatatcagtc tagctgagga
    71041 tgttgcgatt gataccaaca ttgattcacc ttataatgtt tataaaaatg taggtctcat
    71101 gcctggtcca gtcgatagtc caagtctgga tgcgattgag tcaagcatca atcaaactaa
    71161 gagcgataac ctctactttg tagcagatgt cacagaaggc aaggtctact atgctaacaa
    71221 tcaagaagac cacgaccgca atgtcgctga acatgtaaac agcaaattaa actaaacaaa
    71281 ctaaaattat gtgatatttc acataatttt ctttagaaaa tattatcaga agaaagttga
    71341 gaaaaatggc agaaaaaaca tatcctatga cccttgagga aaaggagaaa cttgaaaaag
    71401 aattagaaga attgaaattg gttcgtcgac cagaagtggt agaacgcatt aagattgccc
    71461 gttcatacgg tgatctttca gaaaacagtg agtacgaagc agctaaggat gaacaagcct
    71521 ttgtcgaagg acaaatctct agcttagaaa caaaaatccg ctatgctgaa atcgtcaata
    71581 gcgacgcagt tgcccaggac gaagtagcga ttggtaaaac agtcaccatc caagaaattg
    71641 gcgaggacga agaagaagtt tatattatcg taggttcagc tggtgcggat gcctttgcag
    71701 gtaaggtttc aaatgaaagc ccaattgggc aggccttgat tggcaagaaa acaggtgaca
    71761 cagcaacaat tgaaacgcct gttggtagct atgatgtaaa aatcttgaag gttgaaaaaa
    71821 cagcctaaaa acagaaaaag gagtggggag gcgatgtgct tcactcactc ctttttccat
    71881 tttgctattc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttgccg tatatatggt
    71941 tactgacttt gtcagtttca tctacaacct caaaacagtg ttttgagcta acttcgtcag
    72001 tttcatctac aacctcaaaa ccatgttttg agccgacttc gtcagtttca tctacaacct
    72061 caaaaccatg ctttgagctg acttcgtcag tttcatctac aacctcaaaa ccatgctttg
    72121 agctgacttc gtcagtttca tctacaacct caaaaccatg ctttgagctg acttcgtcag
    72181 ttctatctac aacctcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct
    72241 ctttgatttt tattgagtat tagatgtata gtgcattgaa gttaaaatag tacactttga
    72301 tttctaagac attgttagaa attagattaa attccttaat cgatttgcgc atgttttatt
    72361 tcatttcact atactttaga ttggaaaata aggaatcaca taaatcgcaa gaaataggga
    72421 atctgattcg tgtttataac cgttcaaaaa gagaagaggc tgaaagtgag ccacttaatc
    72481 tttatgtcga agatgaaaag ggcaatctcc tggcaggttt gatagcagag acttttggaa
    72541 attggctaga aatcgagtat ttgtttgtaa aagaggaact gcgagggcaa ggaatcggtt
    72601 caaaactatt gcaacaggca gaaagtgaag ctaagaatcg aaattgttgt tttgcctttg
    72661 tcaatactta ccagttccag gcaccggact tttatcagaa acatggctac aaggaagttt
    72721 tttctttgca agactatctc tacattaggc aaagatatta ttaccaaaag aatctgtaag
    72781 gtgagtatgg aggtataata caaagagagg ctcgcacata agtatggagg tggactgatg
    72841 tatatgagta actatcgata aataccagtt ataacctaga aattgtgtct ttctagacga
    72901 tattgaggac aatataatcg tagccccaaa attaggaatc aagacttatc aggttaagaa
    72961 aagaagtgat gttgttgata ttttaaacaa tttatttaaa ctaaaaactc tctatctatt
    73021 aatccgagat tcccctctcg gattttgtgt tgctttcatt aaatttacag gtaagacttg
    73081 ctagcttcag taaatataca caagtttttc agaatagagt gaaatccaaa agaaaatgga
    73141 aataatgaaa gctcttgtag gcataagaaa acacctctgt gttatacttg ttgttcaacc
    73201 acaaacacaa gaaaggcaca gagatgcaag acaattatac tacaaaagcc aaacatttga
    73261 caatcgatag ccgtcgctta atcgaaagat ggaaaaaaga agggaaatca aatagagaaa
    73321 ttgcctctct gcttggaaaa gttcctcaaa ctatccacac tgaaatcaag cgtgggacag
    73381 tccgacaatg tcttggaaaa gggcgcttca aagaggttta ttctgccgac tatgctcaac
    73441 agtcttatga aaataatcgc aagcgctcgg tcaagaaatc aagcttgacc aaggaactaa
    73501 aggaaaagat tctccactat cataaccaaa aattttcgcc tgaaatgatg gtgatggcta
    73561 aaggggttaa cgtgggaatt tcaaccattt actattggat tcatcatgga aaattggggt
    73621 taagcaaaca ggatctgctt taccctagaa aaggaaaagc gcttaagaaa caggctagca
    73681 ccaactttaa acctgctggt caatccatcg aacagcggtc tgaagctatc aatcttcgct
    73741 tggagaatgg gcattatgag attgatacgg ttctacttac gagagcgaaa aactactgct
    73801 tgcttgtctt gacggatcga aaaagtagac atcagatcat ccgattgatt ccaaataaaa
    73861 gtgctgaggt ggtcaatcag gctctaaaac tcatcttaaa acaacacaag attctttcca
    73921 tcacggcaga taatggaacg gaattcaatc gcttgtctaa tgtattttct gaggagcaca
    73981 tttattatgc acatccctat gcctcttggg aaaggggaac taatgagaat cacaacaggc
    74041 tcattcgtag atggttacct aagagaacca agaaaatgac tcccaaagaa gtcgcattca
    74101 tcgaaaagtg gattaacaac tatcctaaaa aatgcttgga ctacaagtca cccagagaag
    74161 acttctggat ggctaacttg aacttgaaat ttagcaaaat ggaaataatt tttattaaac
    74221 gcttccaata gcggttaaaa gttgacaaat ttaaatttta ggactacact aagtaagtaa
    74281 attttatttt aaaggagaat ttgttatgaa tttaacattt ttaggcttat gtattgcctg
    74341 tatgggcgta tctgtcggtg aaggtttatt gatgaatgga ctgtttaaat cagtagcacg
    74401 ccaaccagat atgctttctg agtttcgtag tttgatgttt ttaggtgttg cctttattga
    74461 aggaactttc tttgtaactc ttgtcttctc atttattatc aaataaatac atggaacgag
    74521 aagaaaaggg aggattttag atggaagaaa gtattaatcc aatcatctct attggtcctg
    74581 ttatcttcaa tctgactatg ttagccatga ctttgttgat tgtgggagtt atttttgtct
    74641 ttatttattg ggcaagccgc aatatgacct tgaaacccaa aggaaagcaa aatgtacttg
    74701 agtatgtcta tgactttgtt attggattta cagaacctaa cattggttcg cgctacatga
    74761 aagattactc actctttttc ctttgtttat tccttttcat ggtgattgcc aataaccttg
    74821 gcttaatgac aaagattcaa acgatcgatg ggactaactg gtggagttcg ccaaccgcta
    74881 atttacagta tgacttaacc ttatcttttc ttgtcatttt gttgacacat atagaaagcg
    74941 ttcgtcgtcg tggatttaaa aaaagtataa aatcttttat gagtcctgtt tttgtcatac
    75001 cgatgaatat cttggaagaa tttacaaact tcttatcttt ggctttgcgg atttttggga
    75061 atatctttgc aggagaggtc atgacgagtt tgttacttct tctttcccac caagctattt
    75121 attggtatcc agtagccttt ggagctaatt tggcttggac tgcattttct gtctttattt
    75181 cctgcatcca agcttatgtt tttactcttt tgacatctgt gtatttaggg aataagatta
    75241 atattgaaga ggaatagaaa ggagtaactg atgcacgtaa cagtaggtga attaattggt
    75301 aattttgttt taatcactgg ctcttttatt cttttgctag tcttgattaa aaaatttgca
    75361 tggtctaata ttacaggcat tttcgaagaa agagctgaaa aaattgcttc agatattgac
    75421 agagctgaag aagcccgtca aaaagcagaa gtattggctc aaaaacgcga agatgaattg
    75481 gctggtagcc gtaaagaagc taagacaatc attgaaaatg caaaggaaac agctgagcaa
    75541 agtaaggcta atatcttagc agatgctaaa ctagaagcag gacacttaaa agaaaaagcc
    75601 aatcaagaaa ttgctcaaaa taaagtagaa gctttacaga gtgttaaggg tgaggtcgca
    75661 gatttgacca tcagcttagc tggtaaaatc atctcacaaa accttgacag tcatgcccat
    75721 aaagcactca ttgatcagta tatcgatcag ctaggagaag cttaatggac aagaaaacag
    75781 taaaggtaat tgaaaaatac agcatgcctt ttgtccaatt ggtacttgaa aaaggagaag
    75841 aagaccgtat cttttcagac ttgactcaaa tcaagcaagt tgttgaaaaa acaggtctgc
    75901 cttctttttt aaaacaagtg gcagtagacg agtcggataa ggaaaaaaca attgcttttt
    75961 tccaagattc tgtgtcacct ttattacaaa actttatcca ggttctggcc tacaatcaca
    76021 gagcaaatct tttttatgat gtgcttgtag attgcttgaa ccgacttgaa aaagaaacaa
    76081 atcgatttga agtgacgatt acgtctgctc atcctctaac tgatgaacag aagactcgtt
    76141 tgctcccttt gattgagaaa aaaatgtctc tgaaagtaag gagtgtaaaa gaacaaatcg
    76201 atgaaagtct cattggtggt tttgtcattt ttgccaatca caagacaatt gatgtgagta
    76261 ttaaacaaca acttaaagtt gttaaagaaa atttgaaata gaaagtggtg ttcttttggc
    76321 aattaacgca caagaaatca gcgctttaat taagcaacaa attgaaaatt tcaaacccaa
    76381 ttttgatgtg actgaaacag gtgttgtaac ctatatcggg gacggtatcg cgcgtgctca
    76441 cggccttgaa aatgtcatga gtggagagtt gttgaatttt gaaaacggct cttatggtat
    76501 ggctcaaaac ttggagtcaa cagacgttgg tattatcatc ctaggtgact ttacagatat
    76561 ccgtgaaggc gatacaatcc gccgtacagg gaaaatcatg gaagtccctg taggtgaaag
    76621 tctgattggt cgtgttgtgg atccgcttgg tcgtccagtt gacggtcttg gagaaatcca
    76681 cactgataaa actcgtccag tagaagcacc agctcctggt gttatgcaac gtaagtctgt
    76741 ttcagaacca ttgcaaactg gtttgaaagc tattgacgcc cttgtaccga ttggtcgtgg
    76801 tcaacgtgag ttgattatcg gtgaccgtca gacagggaaa acaaccattg cgattgatac
    76861 aatcttgaac caaaaagatc aagatatgat ctgtatctac gtcgcgattg gacaaaaaga
    76921 atcaacagtt cgtacgcaag tagaaacact tcgtcagtac ggtgccttgg actacacaat
    76981 cgttgtgaca gcctctgctt cacaaccatc tccattgctc ttcctagctc cttatgctgg
    77041 ggttgctatg gcggaagaat ttatgtatca aggtaagcat gttttgattg tatacgatga
    77101 tctatcaaaa caagcggtag cttatcgtga actgtcgctc ttgcttcgtc gtcctccagg
    77161 tcgtgaagcc ttcccagggg atgttttcta tctccacagc cgtttgcttg agcgctcagc
    77221 taaagtttct gatgaacttg gtggtggatc aattacagcc ctaccattta tcgagacaca
    77281 agcaggagat atctcagcct atatcgcaac caacgtgatt tctatcactg atggacaaat
    77341 cttccttggc gatggcctct tcaatgcagg tattcgtcca gccatcgatg cgggttcatc
    77401 tgtatctcgt gtaggtggtt ctgcacaaat caaagccatg aagaaggttg ctggtacact
    77461 tcgtatcgac cttgcttcat accgtgagtt ggaagccttt actaagtttg gttctgactt
    77521 ggacgcagca acacaggcta agttgaaccg tggacgtcgt accgttgagg tcttgaaaca
    77581 acctgttcac aaaccattac ctgttgagaa acaagtaacc attctttatg ctttgacaca
    77641 tggtttcttg gatactgttc cagtagatga tattgttcat ttcgaggaag agttccatac
    77701 cttctttgat gctcaacatc cagagatttt ggaaaccatt cgtgatacaa aagacttgcc
    77761 agaagaagca gtcttggatg ctgcgattac agagtttctc aatcaatcta gcttccaata
    77821 agaatagagg tgtcagatgg cagtatctct aaatgatatt aaaacaaaaa tcgcctcaac
    77881 aaaaaatacg agtcaaatca ctaatgccat gcaaatggta tcggctgcta agctaggtcg
    77941 ttctgaagaa gctgctcgca acttccaagt ttacgctcag aaagtgcgta aacttttgac
    78001 agatatcctt catggtaatg gagctggtgc ttcaactaat ccgatgttga ttagccgttc
    78061 tgtgaagaag acaggctata tcgttatcac ttcagaccgc ggtttggttg gaggttataa
    78121 ttcctctatt ttgaaagctg ttatggagtt gaaagaagaa taccacccag acggtaaagg
    78181 ttttgaaatg atctgtatcg gtgggatggg agctgatttc tttaaggctc gcggtattca
    78241 accactttat gaattacgtg gcttggcaga ccaacctagc tttgatcaag ttcgtaagat
    78301 tatttcaaaa actgttgaaa tgtaccaaaa tgaactcttt gatgagcttt atgtttgcta
    78361 caaccaccat gtcaatacgc taaccagtca aatgcgtgtg gaacaaatgc ttccgattgt
    78421 tgacttggat ccaaatgaag cggatgaaga gtacagcttg acttttgaat tggaaaccag
    78481 ccgagaagaa attctggagc agttgttgcc tcagtttgca gaaagtatga tttacggtgc
    78541 cattatcgat gccaagacag ctgagaatgc tgcgggtatg acagccatgc aaacagcgac
    78601 agataatgct aagaaagtca tcaatgattt gacaattcag tataaccgtg ccagacaggc
    78661 ggcgattaca caagaaatta cagaaatcgt agcaggtgct agtgccttag aataggctct
    78721 agtccagctc gtatgaaaat gaacttagga cctagttgag ctaggaaccg acagtatctt
    78781 atatagaata ggagaaggag atgagttcag gtaaaattgc tcaggttatc ggtcccgttg
    78841 tagacgtttt gtttgcagca ggggaaaaac ttcctgagat taacaatgca cttgtcgtct
    78901 acaaaaatga cgaaagaaaa acaaaaatcg tccttgaagt agccttggag ttaggagatg
    78961 gtatggttcg tactatcgcc atggaatcaa cagatgggtt gactcgtgga atggaagtat
    79021 tggacacagg tcgtccaatc tctgtaccag taggtaaaga aactttggga cgtgtcttca
    79081 acgttttggg agataccatt gatttggaag ctccttttac agaagacgca gagcgtcagc
    79141 caattcataa aaaagctcca acttttgatg agttgtctac ctcttctgaa atccttgaaa
    79201 cagggatcaa ggttattgac cttcttgccc cttaccttaa aggtggtaaa gttggacttt
    79261 tcggtggtgc cggagttggt aaaaccgtct taatccaaga attgattcac aacattgccc
    79321 aagagcacgg tggtatttca gtatttactg gtgttgggga acgtactcgt gaggggaatg
    79381 acctttactg ggaaatgaaa gaatcaggcg ttatcgagaa aacagccatg gtctttggtc
    79441 agatgaatga gccaccagga gcacgtatgc gtgttgccct tactggtttg acaatcgctg
    79501 aatacttccg tgatgtggaa ggccaagacg tgcttctctt tatcgataat atcttccgtt
    79561 tcactcaggc tggttcagaa gtatctgccc ttttgggtcg tatgccatca gccgttggtt
    79621 accaaccaac acttgctacg gaaatgggtc aattgcaaga acgtatcaca tcaaccaaga
    79681 agggttctgt aacctctatc caggctatct atgtgccagc ggatgactat actgacccag
    79741 cgccagcaac agccttcgct cacttggatt caacaacaaa cttggaacgt aaattggtac
    79801 aattgggtat ctacccagcc gttgacccac ttgcttcaag ctcacgtgcc ttggcacctg
    79861 aaatcgttgg agaagagcac tatgcagttg ctgctgaagt aaaacgtgtc cttcaacgtt
    79921 accatgaatt gcaagatatc attgctatcc ttggtatgga tgagctttct gatgaagaaa
    79981 agaccttggt tgctcgcgcc cgtcgtatcc agttcttctt gtcacaaaac ttcaacgttg
    80041 cggaacaatt tactggtcag ccaggttctt atgttccagt tgctgaaact gtacgtggct
    80101 ttaaggaaat ccttgatggt aaatacgacc acttgccaga agatgccttc cgtggtgtag
    80161 gttctatcga agatgtgatt gcaaaagctg aaaaaatggg attttaagag gtgatctatg
    80221 gctcagttaa ctgtccagat cgtgacacca gatggtctcg tctatgatca ccatgccagc
    80281 tatgtatcgg ttcgaactct ggatggtgag atggggatct tgccacgaca tgaaaatatg
    80341 attgcagttt tagcagttga tgaagtaaag gtaaaacgta tcgataataa agatcacgtg
    80401 aactggattg cagtaaacgg tggcgttatt gaaattgcca atgatatgat cacaatcgtc
    80461 gctgactctg cagaacgtgc tcgtgatatc gatatcagtc gtgcagaacg tgccaaactt
    80521 cgtgcagaac gtgcaattga agaagcacaa gacaaacatt tgattgacca agaacgtcgt
    80581 gctaagattg ctttgcaacg tgctattaac cgtattaatg tcggaaatag actataagaa
    80641 aaaatggctc tttgtcaact gtagtgggtt gaagtcagct aagctcgaga aaggacaaat
    80701 tttgtccttt cttttttgat attcagagcg ataaaaatcc gttttttgaa gttttcaaag
    80761 ttccgaaaac caaaggcatt gcgcttgata agtttgatga gattattggt cgcttccaat
    80821 ttggcgtttg aatagggtag ttgaagggcg ttgacgattt tctctttgt
//
LOCUS       DAVLTG010000003        79796 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLTG010000003 DAVLTG010000000
VERSION     DAVLTG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.003"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(75..1094)
                     /gene="adhP"
                     /locus_tag="VYN12_000175"
     CDS             complement(75..1094)
                     /gene="adhP"
                     /locus_tag="VYN12_000175"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1414629.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1433..2245)
                     /locus_tag="VYN12_000176"
     CDS             complement(1433..2245)
                     /locus_tag="VYN12_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1414630.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKETIKKVAEKGHQIIITTG
                     RPYRMSKDFYHELGLNTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVRRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPENQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2435..3853
                     /locus_tag="VYN12_000177"
     CDS             2435..3853
                     /locus_tag="VYN12_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1414631.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGILL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFKDLKTIFGAALGSEGLGALISDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTSIGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLASLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQAK
                     DVHVMIWILDALFILNYISMAL"
     gene            3958..4665
                     /locus_tag="VYN12_000178"
     CDS             3958..4665
                     /locus_tag="VYN12_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1414632.1"
                     /translation="MIKKNIWDEVLNRGKWLIIFLVGLLFSQFPLALATFLTSRKFPL
                     LQTGLLVGALSLVVLTVFIIGARKTQLASFGLSFFKAKDLARLALSYLVILAFNILGV
                     VLLHLMNETTTSNQSNINDLVQNSSLISSFFLLLLIAPICEEILCRGVIPKKLFRGKE
                     NVGYIVGAIIFALLHLPTNLPSLLIYGGMSTVLTWTVYKTQRLEMSILLHMIVNGIFF
                     CLLALVVILSRTLGISV"
     gene            4759..5739
                     /gene="folP"
                     /locus_tag="VYN12_000179"
     CDS             4759..5739
                     /gene="folP"
                     /locus_tag="VYN12_000179"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1414633.1"
                     /translation="MMKSLEGVTDMSTKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMARVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFETLPIEDLMDAFFERALARANQAGIAQENILLDLGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5741..7063
                     /locus_tag="VYN12_000180"
     CDS             5741..7063
                     /locus_tag="VYN12_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1414634.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     QSLLEGEAVANLQSTTEFEIITALAYDYFAAEQVEVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVSHQKSVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     HGRELASNDLLGQALEETSWPGRLEVVSRDPLMILDGAHNPHAIKALLATLQERFADY
                     RKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFDDSRATDESVLEEAAKSRNLNYQG
                     WQDFLEQKLTDKKEEKKTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            7044..7598
                     /gene="folE"
                     /locus_tag="VYN12_000181"
     CDS             7044..7598
                     /gene="folE"
                     /locus_tag="VYN12_000181"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1414635.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMEYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7757..8569
                     /gene="folK"
                     /locus_tag="VYN12_000182"
     CDS             7757..8569
                     /gene="folK"
                     /locus_tag="VYN12_000182"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1414636.1"
                     /translation="MDQLQIKDLEIFAYHGLFPSEKELGQKFVVSAILFYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETTEDLIETVAYKLVERTFEAYPLVQEMKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNQGIHILKESSVLTT
                     EPWGGVEQDSFANQVVEVETWLPAPVLLESLLAIESEMGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYNALKQ"
     gene            complement(8615..8932)
                     /locus_tag="VYN12_000183"
     CDS             complement(8615..8932)
                     /locus_tag="VYN12_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1414637.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9289..9735
                     /gene="rplM"
                     /locus_tag="VYN12_000184"
     CDS             9289..9735
                     /gene="rplM"
                     /locus_tag="VYN12_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1414638.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9755..10147
                     /gene="rpsI"
                     /locus_tag="VYN12_000185"
     CDS             9755..10147
                     /gene="rpsI"
                     /locus_tag="VYN12_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1414639.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10409..10831)
                     /locus_tag="VYN12_000186"
     CDS             complement(10409..10831)
                     /locus_tag="VYN12_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1414640.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            10978..11154
                     /locus_tag="VYN12_000187"
     CDS             10978..11154
                     /locus_tag="VYN12_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414641.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            11555..13768
                     /locus_tag="VYN12_000188"
     CDS             11555..13768
                     /locus_tag="VYN12_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1414642.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13990..14466)
                     /locus_tag="VYN12_000189"
     CDS             complement(13990..14466)
                     /locus_tag="VYN12_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1414643.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQR
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINTFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14689..17892
                     /locus_tag="VYN12_000190"
     CDS             14689..17892
                     /locus_tag="VYN12_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1414644.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18245..18630
                     /gene="tnpA"
                     /locus_tag="VYN12_000191"
                     /pseudo
     CDS             18245..18630
                     /gene="tnpA"
                     /locus_tag="VYN12_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(19009..19638)
                     /locus_tag="VYN12_000192"
     CDS             complement(19009..19638)
                     /locus_tag="VYN12_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1414645.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(19648..20649)
                     /locus_tag="VYN12_000193"
     CDS             complement(19648..20649)
                     /locus_tag="VYN12_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1414646.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(20680..21321)
                     /locus_tag="VYN12_000194"
     CDS             complement(20680..21321)
                     /locus_tag="VYN12_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1414647.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(21340..22155)
                     /locus_tag="VYN12_000195"
     CDS             complement(21340..22155)
                     /locus_tag="VYN12_000195"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1414648.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            22426..22860
                     /locus_tag="VYN12_000196"
     CDS             22426..22860
                     /locus_tag="VYN12_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1414649.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            22872..24062
                     /locus_tag="VYN12_000197"
     CDS             22872..24062
                     /locus_tag="VYN12_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1414650.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDEFCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            24073..24564
                     /locus_tag="VYN12_000198"
     CDS             24073..24564
                     /locus_tag="VYN12_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1414651.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            24579..25358
                     /locus_tag="VYN12_000199"
     CDS             24579..25358
                     /locus_tag="VYN12_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1414652.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            25345..26163
                     /locus_tag="VYN12_000200"
     CDS             25345..26163
                     /locus_tag="VYN12_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1414653.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            26163..26456
                     /locus_tag="VYN12_000201"
     CDS             26163..26456
                     /locus_tag="VYN12_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1414654.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            26478..28379
                     /locus_tag="VYN12_000202"
                     /pseudo
     CDS             26478..28379
                     /locus_tag="VYN12_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
     gene            28439..29440
                     /locus_tag="VYN12_000203"
     CDS             28439..29440
                     /locus_tag="VYN12_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1414655.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(29550..29885)
                     /locus_tag="VYN12_000204"
     CDS             complement(29550..29885)
                     /locus_tag="VYN12_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414656.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRISVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(29896..30138)
                     /locus_tag="VYN12_000205"
     CDS             complement(29896..30138)
                     /locus_tag="VYN12_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414657.1"
                     /translation="MKKEKKQLRHPGLKAGSIYGIVIFFIIPPIDTLTSDNPNFITSL
                     LNTKHIFKTILGAFFFGVMMHIVDSLRIARAKKDQD"
     gene            complement(30149..30691)
                     /locus_tag="VYN12_000206"
     CDS             complement(30149..30691)
                     /locus_tag="VYN12_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1414658.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLRYPGLKAGLFFGLWIFFITPLLDILIGEGQDYFQSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKAKKDQDND"
     gene            complement(30707..30901)
                     /locus_tag="VYN12_000207"
     CDS             complement(30707..30901)
                     /locus_tag="VYN12_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1414659.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            31067..32017
                     /gene="rsmH"
                     /locus_tag="VYN12_000208"
     CDS             31067..32017
                     /gene="rsmH"
                     /locus_tag="VYN12_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1414660.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQERLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            32029..32346
                     /gene="ftsL"
                     /locus_tag="VYN12_000209"
     CDS             32029..32346
                     /gene="ftsL"
                     /locus_tag="VYN12_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1414661.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            32350..34602
                     /gene="pbpX"
                     /locus_tag="VYN12_000210"
     CDS             32350..34602
                     /gene="pbpX"
                     /locus_tag="VYN12_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1414662.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIIPGTEQVSQQTVDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTKDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPSGEYFNSSELKIADVTIRDWDVNDGLTTGRMMTFLQGF
                     ALSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     NYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            34604..35584
                     /locus_tag="VYN12_000211"
     CDS             34604..35584
                     /locus_tag="VYN12_000211"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1414663.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLFTSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGIGLLASLLTLAILYLM"
     gene            35724..35912
                     /locus_tag="VYN12_000212"
     CDS             35724..35912
                     /locus_tag="VYN12_000212"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414664.1"
                     /translation="MLEIDLTVLIDLSCSYFILLYSFEMVDRTDEVSSKHGFEVVDKA
                     KLMWFEEVFEECKKILVS"
     gene            36189..38294
                     /locus_tag="VYN12_000213"
     CDS             36189..38294
                     /locus_tag="VYN12_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1414665.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AYYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            38755..39090
                     /locus_tag="VYN12_000214"
                     /pseudo
     CDS             38755..39090
                     /locus_tag="VYN12_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(39157..39639)
                     /locus_tag="VYN12_000215"
     CDS             complement(39157..39639)
                     /locus_tag="VYN12_000215"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1414666.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(39734..41218)
                     /locus_tag="VYN12_000216"
     CDS             complement(39734..41218)
                     /locus_tag="VYN12_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1414667.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            41371..42978
                     /locus_tag="VYN12_000217"
     CDS             41371..42978
                     /locus_tag="VYN12_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1414668.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            43143..43310
                     /locus_tag="VYN12_000218"
     CDS             43143..43310
                     /locus_tag="VYN12_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV1414669.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(43303..43812)
                     /locus_tag="VYN12_000219"
                     /pseudo
     CDS             complement(43303..43812)
                     /locus_tag="VYN12_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            44063..45508
                     /locus_tag="VYN12_000220"
     CDS             44063..45508
                     /locus_tag="VYN12_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1414670.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLMSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEHPDYASKIKKIYTKGFTKKVEAP
                     KTSKDQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALSFVRERYSLADGDRDRGRNQQKVIVAILQKLTSS
                     EALKNYSRIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGMGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            45510..46241
                     /gene="cps4B"
                     /locus_tag="VYN12_000221"
     CDS             45510..46241
                     /gene="cps4B"
                     /locus_tag="VYN12_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV1414671.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTSDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHIIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            46250..46942
                     /gene="cpsC"
                     /locus_tag="VYN12_000222"
     CDS             46250..46942
                     /gene="cpsC"
                     /locus_tag="VYN12_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV1414672.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPAMTPSSPNVRRNTLVGFLGGAAVTVITVLLIELLDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     gene            46952..47641
                     /locus_tag="VYN12_000223"
     CDS             46952..47641
                     /locus_tag="VYN12_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1414673.1"
                     /translation="MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSY
                     GSYGNYRKQKK"
     gene            47656..49017
                     /locus_tag="VYN12_000224"
     CDS             47656..49017
                     /locus_tag="VYN12_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1414674.1"
                     /translation="MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIVGSLVGLILCG
                     LVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            49023..49766
                     /locus_tag="VYN12_000225"
     CDS             49023..49766
                     /locus_tag="VYN12_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEV1414675.1"
                     /translation="MNERIQILGITIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCYEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMKHLLELSNEKG
                     YSVYFFGAKEDVLQDMLKIFEERYPALNVVGYRNGYFSPEDEKHIQEDIKEKKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQNAHLEWLFRVAN
                     EPKRLFKRYFVGNVSFIRKVLRAKRGYKL"
     gene            49763..50587
                     /locus_tag="VYN12_000226"
     CDS             49763..50587
                     /locus_tag="VYN12_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV1414676.1"
                     /translation="MNQTEIVKLIQKVELDAIKEFQKICKENNIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREGYDKLPGIFKDRIIAGKYQVLAYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSFLRKLYFGKVYWYRFLASLGTTYVGDH
                     VDMHSAKQKLIIGFFKKLGFAKLFPQNYVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDAFFKVPTEYDRYLKRLYGENYLHEEPSDDEKKSHLGGQ"
     gene            50589..51467
                     /locus_tag="VYN12_000227"
     CDS             50589..51467
                     /locus_tag="VYN12_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1414677.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTG
                     EKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEF
                     EKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLA
                     LKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNF
                     ESTSYFLKLMKENEGV"
     gene            51468..52802
                     /locus_tag="VYN12_000228"
     CDS             51468..52802
                     /locus_tag="VYN12_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEV1414678.1"
                     /translation="MTYLFLLCLTLFLLTFFYFFAFNQDLIAPPVVMSVMFLISSVFA
                     LINVQNWNIEYSGLAYLLIISGIIVFSMPLLALNSPILNTKIKVTDRLIDIQFWKIAL
                     TIIVDLIILYLYRREIHNLALSHGYTGSNFQWFFRNATSYEGELTVRTSIRVLIRIID
                     VSAYIFGYTFINNFFIYSHKRSKDLLLLVPFLIFISKTLLSGGRLDIIKILIAYVVMA
                     YIQQKRKVGWDKVISHKYMRLGFVGLIAGIPTFYYSLFLSGRSTTRTVFESISTYLGG
                     SIQHFNQYIQNPIGVAEVFGDESFVAIMNILGNLGFVNYNSTVHLEFRQLGITMGNVY
                     TFFRRPWHDFGLVGMYIFSFVVGVFFAIFYLKLRKSRAGFKLDIHTIIYSYFFYWIFL
                     SSIEQYSFTTISLFTLVFIVLVYLMAFFYWNLDFHRGKLVIKLSDTSIKSEN"
     gene            52830..54254
                     /locus_tag="VYN12_000229"
     CDS             52830..54254
                     /locus_tag="VYN12_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414679.1"
                     /translation="MNSKIKNILTNFSYVISSNLLTVLTSSLVVLIFPKLMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYNNLDRKQFYSQMILFSSFLMIISLLLF
                     GLNVLAVTDSNARYIYNMTIISMIITNLRTLYVYVLQMTNRLKDSSIILLSDRVLYVL
                     LLFLFIVFGWHEYKVMILADILGRSFSLILSFWICKDIVFQPLSKFIFNIKESFDNIR
                     VGINLMLSNIASSLIIGIVRLGIQWNWNIETFGKVSLTLSVSNLLMTFINAIGLVVFP
                     LLRRTKAENLPKIYSNLRNVLMLIMFAILLIYYPLKIVLDLWLPAYQDALIFMTLIFP
                     MSVYEGKMALVINTYLKALRMERDILRVNALVMLISMGVTLVTTYLLNSLELTVVSIV
                     VLLALRSIIAELILSKKLDVSVKKDIVLEFLLTLVFISSSWYLPIGLAVIVYTIAYGL
                     YLYLKHEDIKTYLAYFKASKKTSN"
     gene            54319..55407
                     /gene="wecB"
                     /locus_tag="VYN12_000230"
     CDS             54319..55407
                     /gene="wecB"
                     /locus_tag="VYN12_000230"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEV1414680.1"
                     /translation="MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMV
                     SPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
                     GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYEDVKVIYPIHKNPLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSG
                     EYKKMSQASNPYGNGDASQQIVQILRGI"
     gene            55570..56439
                     /gene="rfbA"
                     /locus_tag="VYN12_000231"
     CDS             55570..56439
                     /gene="rfbA"
                     /locus_tag="VYN12_000231"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1414681.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            56440..57033
                     /locus_tag="VYN12_000232"
     CDS             56440..57033
                     /locus_tag="VYN12_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1414682.1"
                     /translation="MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            57045..58091
                     /gene="rfbB"
                     /locus_tag="VYN12_000233"
     CDS             57045..58091
                     /gene="rfbB"
                     /locus_tag="VYN12_000233"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1414683.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(58153..59007)
                     /gene="rfbD"
                     /locus_tag="VYN12_000234"
     CDS             complement(58153..59007)
                     /gene="rfbD"
                     /locus_tag="VYN12_000234"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1414684.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            59253..61235
                     /locus_tag="VYN12_000235"
     CDS             59253..61235
                     /locus_tag="VYN12_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414685.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKAEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAVVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGGITDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            61536..66845
                     /locus_tag="VYN12_000236"
     CDS             61536..66845
                     /locus_tag="VYN12_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1414686.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDTDNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDASTVEKPEFKLSSLASDEDKAPAPELKQE
                     VTKRETAEQSLPATGESQSDTALFLAGVSLALSALFVAKTKKD"
     gene            complement(67013..69178)
                     /locus_tag="VYN12_000237"
     CDS             complement(67013..69178)
                     /locus_tag="VYN12_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1414687.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGSRHQSSNVSFGINQAVETNRDWGSAMKPITDYAPALEYDIYDSTAS
                     IVHDVPYNYPGTDTPLYNWDKVYFGNITIQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKKYGASSEKMAAAYAAFANGGIYHKPMYINKIVFS
                     DGSSKEYADPGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLPQAGKTGTSNYTDD
                     EIENYIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFYVAAKVYRSMMTY
                     LSEDNNPGDWTMPEGLYRSGEFVFKKGARSAWTAPAPQQAPTPESSSSTSESSTSQSS
                     STTPSTNNSANNNTNNQQPNTTPGQQNQNQNQNPQPAQP"
     gene            complement(69175..69771)
                     /gene="recU"
                     /locus_tag="VYN12_000238"
     CDS             complement(69175..69771)
                     /gene="recU"
                     /locus_tag="VYN12_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1414688.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            69837..70364
                     /locus_tag="VYN12_000239"
     CDS             69837..70364
                     /locus_tag="VYN12_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1414689.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            70434..70763
                     /gene="gpsB"
                     /locus_tag="VYN12_000240"
     CDS             70434..70763
                     /gene="gpsB"
                     /locus_tag="VYN12_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1414690.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            70784..71164
                     /gene="rnpB"
                     /locus_tag="VYN12_000241"
     ncRNA           70784..71164
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYN12_000241"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            71249..72406
                     /locus_tag="VYN12_000242"
     CDS             71249..72406
                     /locus_tag="VYN12_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1414691.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            72418..73812
                     /gene="mapZ"
                     /locus_tag="VYN12_000243"
     CDS             72418..73812
                     /gene="mapZ"
                     /locus_tag="VYN12_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1414692.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            73888..75312
                     /gene="gndA"
                     /locus_tag="VYN12_000244"
     CDS             73888..75312
                     /gene="gndA"
                     /locus_tag="VYN12_000244"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1414693.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            75324..76013
                     /locus_tag="VYN12_000245"
     CDS             75324..76013
                     /locus_tag="VYN12_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1414694.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            76111..77127
                     /gene="cbpC"
                     /locus_tag="VYN12_000246"
     CDS             76111..77127
                     /gene="cbpC"
                     /locus_tag="VYN12_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1414695.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMATGWYQDGSTWYYLNASNGGMKTGWFQVNGKWYYAYGSGALAVNTTVDGYSVNYNG
                     DWVR"
     gene            complement(77246..78478)
                     /locus_tag="VYN12_000247"
     CDS             complement(77246..78478)
                     /locus_tag="VYN12_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1414696.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILYQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(78521..79108)
                     /locus_tag="VYN12_000248"
     CDS             complement(78521..79108)
                     /locus_tag="VYN12_000248"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414697.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHIFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            complement(79008..79346)
                     /locus_tag="VYN12_000249"
     CDS             complement(79008..79346)
                     /locus_tag="VYN12_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV1414698.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLPLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
BASE COUNT        24417 a        14244 c        17578 g        23557 t
ORIGIN      
        1 tgaattctta tttaaaaatt taatataaaa aagttagaag aagcttccaa cttttaaaat
       61 aggtttctat tagattagtg ggtgaagtcg agtaccatac gtccttggat ttgacctttt
      121 tccatttcgt cgaaaatggc aacagcatct tctactggac gtttttgaac aactggggct
      181 accagacctt ctgcaccaaa ttggaaggct tcttctaagt ctttacgagt tccgacaaga
      241 gaaccgatga cttggattcc atcgaggact gttttaacga tactgagttc catcatttca
      301 gaaggaagac caacagcgac gacgcgacca ccagcacgaa cggagtcaac agcctggttg
      361 aaggcaactt tagacacagc agttacgaca gctgaatgag ctcctccatc agtttttcct
      421 ttaatgagtc cagctacatc ttcaacttcg aggccgttaa tcacaatgtc agcgcctact
      481 tcttttgcaa gggcaagttt gtcattgttg atatcgactg cgataacatg agcattgaat
      541 acttttttag cgtattgaac agcgaggtta ccaagtccac cagcaccgta aagaacaacc
      601 cattggcctg gttcaacttt tgcttctttg atagctttat aggttgttac tccagcacat
      661 gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa ccttgacagc atagtcagca
      721 gttacgatac attgttcagc cataccaccg tctactgagt agccagcatt tttcactgta
      781 cggcaaaggg tttcgcgacc agttgtacag tattcgcaag tgccacatcc ttcaaagaac
      841 caagcaacgc tgacgcggtc accgacttta aggcttttca catctggagc aatctcttta
      901 acgataccga taccttcgtg cccaagaaca cgtcctggga cttgaccaaa gtcaccatga
      961 gcaacgtgga gatcggtgtg gcaaacgcca cagtattcaa cttctacaag tgcttcccca
     1021 gtttcaagtg gacggagtac tttttcttca atagcaacac cagtgctttc tggatttaca
     1081 acaacagctt tcatagctat cctccttgat attgaccgag aacagggaca acgggactgg
     1141 attgattttt tgtcaacaga gtcgagtgtg acgagctctc ttgtatttat atgtgaagta
     1201 tatcacaaaa gaaagccttt tccaaggttt tggagacaaa aagtagaaca atcgattaac
     1261 tggttgatga gactgtgaaa agagcacaaa gaccagcttg caagctggtc atactcttcg
     1321 aaaatctctt caaaccacgt cagcttcatc tacaacctca aagcagtgct ttgagcaacc
     1381 tacggctagc ttcctagttt gctctttgat tctcattgag tatcagtata ggttataaga
     1441 ataagtcttg tagggttttg gcaaccccat cttggtcgtt ggtaagggaa atttgctcat
     1501 ctgcataagg gagtagctct ggattggcat ttttcatggc ataacccttc ccagcaaaag
     1561 cgagcatttc ggtatcattg tgttcatctc caaaggcaat caaatctttt ttgtcacgat
     1621 tcattatctt gagcaagtag tccaaagcaa aggccttgtt gacacctttt ggggtacatt
     1681 caaggatatt gagcggacct ccccaggtat tgatagacag ttgatgctgg tagaaggcgt
     1741 tcatttcttt tgccagagca tatttgtcac tggctctagt ctgtaacaga atacagttag
     1801 gatccttggt tactaactca ggctgaaatt gattttcagg ctggaaagct tctacaccaa
     1861 atagtttggg attagcaatt tcttcattgg gatttgtaat gtaaaatttt ttacggtatt
     1921 ctccagcgat aaaatcggct tgaatgtcct ctgaacgtcg aaccatgtct agcagatatt
     1981 ttttgtctac agttaaacac ttttcaaaat cccaaacttg gtctggtaaa tgagtaaggg
     2041 agccgttgaa attaatcata ggagtgttta agcctagttc atggtaaaaa tcttttgaca
     2101 tgcggtaagg gcgacccgtc gtaataataa tctgatggcc tttttcagca acttttttaa
     2161 tggtttcttt ggtaaagtca gaaatttgac tgtctgagtt gagcagggtt ccatccaggt
     2221 caactgcaat aatttttttc gtcataggga cctttctagt gtcttttcag ataagatgtc
     2281 tactattata acagaaagca ggcagaaaag cagattcgaa acaaaaaaag aaatttcatc
     2341 aaattcttaa ataaatcaaa caaagatatt gaaaaagtga atgataaatg atataattct
     2401 attattgttc gtaaaaatta aaaggagatt gataatggac aaattattta aactaaaaga
     2461 gaacggtaca gacgttcgta cagaggttct cgctggttta acaactttct ttgcaatgag
     2521 ctatattctc tttgtaaacc cacaaattct ttcgcaaaca ggaatgcctg ctcagggtgt
     2581 attcctcgca acgattattg gtgcagttgc tggtaccctg atgatggcct tctacgctaa
     2641 cttaccttat gcccaagcgc caggtatggg actcaatgcc ttctttacct ttacagttgt
     2701 attcggactt ggttattctt ggcaagaagc cctagctatg gtcttcatct gtggaattat
     2761 ctcattgatt attaccttga caaatgttcg taaaatgatc attgaatcga ttcccaatgc
     2821 tcttcgctca gctatttcag ctggtatcgg tgtcttcctt gcctatgtag ggattaagaa
     2881 tgctggactt ttgaaattta cgattgatcc aggtaactat actgttgtag gagaaggggc
     2941 tgacaaagct caagcaacga ttgcagcaaa ctcttcagca gttccaggat tggtcagctt
     3001 taataatcca gctgttttgg tggctcttgc aggactcgct atcacaattt tctttgtcat
     3061 caaaggaatt aaagggggaa ttctcctctc tatcttgaca acaactgttc ttgctattgc
     3121 agttggtttg gtagatttgt caagcatcga ttttgctaat aaccatgttg gtgcagcttt
     3181 taaagatttg aagacaatct ttggtgcagc tcttggttca gaaggtttgg gagctttgat
     3241 ttcagataca gctcgcttgc ctgaaactct gatggctatt cttgcctttt cattgacaga
     3301 tatttttgat acaattggta ccttgatcgg tacaggtgaa aaagttggta tcgtagcgac
     3361 aaatggtgaa aatcatcaat cagctaagtt agacaaggct ctttactctg acttgattgg
     3421 tacttcaatt ggtgccatcg caggtacttc gaacgtaacg acttatgttg agtctgctgc
     3481 tggtatcggt gcaggtggac gtactggttt gacagccttg gtcgtggcaa tctgttttgc
     3541 gatctcaagc ttctttagcc cacttctagc gattgtacca acagccgcta cagctccaat
     3601 cttgattatc gttgggatta tgatgttggc tagcttgaaa aatatccatt gggacgatat
     3661 gtctgaagcg gttcctgctt tcttcacatc tatctttatg ggattcagct actctatcac
     3721 tcaagggatt gcagttggtt tcttgactta cactttgact aagcttgtca aaggtcaagc
     3781 taaagatgtt catgtcatga tttggatttt ggatgctttg tttatcctta actacatcag
     3841 tatggcacta taaatgctat aatataaaaa ggggttctcc cctttttata ttatagttac
     3901 ttgaaaattg cttcaaacta ggtaggtgat tttgattgaa tggtaggagt ataattgatg
     3961 ataaaaaaga atatttggga tgaagtatta aacaggggga agtggttaat aatctttcta
     4021 gtagggcttt tgttttctca gtttccttta gccctagcaa cttttttaac tagcagaaaa
     4081 tttccactgc ttcaaacggg actattagta ggggccttat ctcttgtggt tttaactgta
     4141 tttataatag gtgctaggaa aacacagttg gctagttttg gtttatcgtt tttcaaggct
     4201 aaggatttgg ctagattggc cttaagctat ctagtgattc ttgcctttaa tattcttggt
     4261 gtggtcttac tgcatttgat gaatgaaaca acaaccagca atcaatcaaa tattaatgat
     4321 ttggtccaga atagttcctt aatttccagt tttttcttac tgcttctaat agctcctatt
     4381 tgtgaggaga ttttatgtcg aggagtgatt cctaaaaaac tctttcgtgg taaagaaaat
     4441 gtgggttata tagtcggtgc tattatcttt gccttgcttc atttaccgac aaatctacct
     4501 tctcttctta tctatggagg aatgtcaact gtgctaactt ggacagttta taaaacccaa
     4561 cgtttggaaa tgtctatctt acttcacatg attgttaatg gaattttttt ctgtttgttg
     4621 gctctcgtgg tgattttgag tcggacatta gggatctctg tttaagattt ttgacaattg
     4681 cttacttgtt tctgctggga aaaagatgaa tgcaatcgtg tccatctttt tctttttatg
     4741 gtaaaataga gaaataatat gatgaaaagc cttgagggag tgaccgatat gtcaactaaa
     4801 gccaatcatg caaagacagc tatttgcgga attatcaatg taaccccaga ctccttttcg
     4861 gatggtggtc aattttttgc tcttgagcag gcactccagc aggctcgtaa attgatagca
     4921 gaaggggcta gcatgctaga tatcggcgga gaatcgactc ggccgggaag tagctatagc
     4981 tatgttgaga tagaagagga aatccagcgt gttgttccag ttattaaggc tattcgcaag
     5041 gaaagtgatg tcctcatctc tattgatact tggaagagcc aggtagcaga ggctgctttg
     5101 gctgctggtg ccaatctagt caacgatatc actggtctca tgggcgatga aaaaatggct
     5161 cgtgtggttg ctaaggctgg agcgaaagtg gttatcatgt ttaatccagt catggctcgt
     5221 cctcagcatc ctagctcgct catctttcct cattttggct ttggtcaagc ttttacagag
     5281 gaagagttag ctgactttga aacattgcca atcgaagact tgatggatgc tttctttgaa
     5341 cgagcactag cgagagcaaa tcaagctgga attgcacaag aaaatatcct gttggatctg
     5401 ggaatcggct ttggtctgac caagaaagaa aatctgcttc ttttacggga cctggataaa
     5461 ctacatcaga agggctatcc aatctttctt ggagtgtcgc gcaagcggtt tgtcatcaat
     5521 atccttgaag aaagtggttt tgaagtcaat cctgagacag aacttggttt ccgaaatcgg
     5581 gacacggctt cggctcatgt aactagtatc gctgcgagac agggtgtaga agtggtgcgc
     5641 gtgcatgacg tagctagtca caggatggca gttgaaattg cctctgccat tcgtctggct
     5701 gatgaagcgg aaaatttaga tttaaaacaa tataaataag atgaaagaaa ttgaaaataa
     5761 tcagtggatt gctaactacc ggacggatca accgcatttt ggcttggaac gaatggtgga
     5821 actgttagcc ttgcgtggaa atccccatct caaactcaag gtcatccata tcggagggac
     5881 taacggcaag ggttcgacca ttgctttttt gaagaatatg ctggaaaagc tagggctgag
     5941 agttggggtg ttcagctcgc cctatctcat tcattacaca gaccagatta gcatcaatgg
     6001 ggaatccatt ccagaggcta ggctagaagc cctcatggca gactatcagt ctttgctgga
     6061 gggagaagcg gtcgccaatt tacagagtac aaccgagttt gagattatca cagccctggc
     6121 ctatgactac tttgccgcag agcaagtaga agtggctatc atggaagtcg gtatgggtgg
     6181 acttttagat agtaccaatg tctgtcagcc cattttgaca ggaattacga ctattggctt
     6241 ggaccatgta gccctacttg gtgatacctt ggaagccata gcagagcaga aagctggtat
     6301 tatcaaacaa ggtattccct tggtgacagg tcgtatcgct ccagaagctt tggctgtgat
     6361 tgaccgcatt gcggaaggga aagatgcgcc gagacttgcc tacgggacag attatcaggt
     6421 cagccatcaa aagagtgtgg ttacaggcga agtctttgac tatacaagtg ttgtcaggca
     6481 aggtcgcttc caaactggcc tgcttggctt gcaccagata gagaatgctg ggatggccat
     6541 agctttactt gatacttttt gtcaagaaca tggtcgagag ctagcaagca atgacctgct
     6601 tggtcaagcc ttggaagaaa caagttggcc agggcgtttg gaagttgtgt cgagagaccc
     6661 cctgatgatt ttggatggag cccacaatcc ccatgcgatc aaggccttat tggcaacctt
     6721 gcaagaacgc tttgcggatt atcgtaagga aatcctcttt acttgcatca aaaccaaggc
     6781 cttagaggat atgttggact tgctgggggc catgccagat accgagctaa ctctaacaca
     6841 ttttgacgat agtcgggcga ctgatgaaag cgtgctggaa gaggcggcta agtctagaaa
     6901 tctcaactac caaggttggc aggattttct agagcagaaa ttgacagata aaaaagaaga
     6961 gaaaaaaaca gttaggattg tcacgggttc cttgtatttc ttgagccaag tgagagccta
     7021 tctgatggag aggaaaaacg aaaatggata cacaaaagat tgaagcagct gtaaaaatga
     7081 ttatcgaggc tgtcggagag gacgctaacc gtgagggctt gcaggaaacg cctgctcgag
     7141 tggcccgtat gtaccaagag attttttcag gtcttggtca aacagcggag gaacatttgt
     7201 caaaatcctt tgagattatt gatgacaaca tggtagtaga aaaggatatc tttttccaca
     7261 ctatgtgtga gcaccacttc ttgccatttt atggtagagc gcacatagcc tatattccag
     7321 atggtcgtgt ggcaggtttg tctaagctag cccgtacggt tgaagtttat tcgaaaaaac
     7381 cacaaattca agaacgattg aatatcgaag tggccgatgc cttgatggag tatctaggtg
     7441 ctaaaggagc ctttgttgtc attgaggcgg aacatatgtg tatgagcatg cgtggtgtca
     7501 gaaaaccagg cactgcaacc ttgacgacag tagctcgtgg tctatttgaa acagataagg
     7561 acctccgaga tcaggcttat cgtttaatgg gactataata ttcttcgaaa atcaaattca
     7621 aaccacgtca gcctccatct gcaacctcaa aacagtgttt tgagcagcct gcggctagtt
     7681 tcctagtttg cactttgatt ttcattgagt ataaaaagaa tccgctttgg gcggattttt
     7741 cgagaaagga atcattatgg atcaactgca gattaaggat ttggaaattt ttgcctatca
     7801 tggtcttttt ccgagtgaga aagaattggg gcaaaagttt gtcgtttcag ctatcctatt
     7861 ctatgatatg accaaggcgg cgacagattt ggatttaaca gcctctgtcc attatggaga
     7921 actgtgtcag cagtggacga cttggtttca ggaaacaact gaggacttga ttgaaacggt
     7981 agcctacaaa ctagtagaac gtacctttga ggcttatcct cttgtccaag aaatgaagct
     8041 ggaactgaaa aaaccttggg caccggtgca tttgccacta gatacttgct cggtaaccat
     8101 tcatcgccgc aagcaacgag cctttatcgc cctaggaagc aatatgggag ataaacaagc
     8161 aaacttgaaa caagccattg agaaaatgcg aaatcaaggt atccatattc tcaaagagtc
     8221 cagtgtcttg acgacggagc cttggggtgg tgtggagcaa gatagctttg ctaatcaagt
     8281 ggttgaggtt gaaacctggc taccggcacc ggtcttgtta gaaagcttgt tagccattga
     8341 gtcagagatg ggacgggtga gagaagtaca ttgggggcct cgtttgattg atttggactt
     8401 gctctttgtg gaggaccaga tcctttatac agatgacctt atcttgcccc atccttacat
     8461 agcggaacgc ctttttgtcc ttgagtcctt acaggaaatt gcgcctcatt ttatccatcc
     8521 gacattaaag caaccgatcc gcaacttgta taatgctttg aaacaataga aaaaactcta
     8581 gttttcagta gtttgtaact gaaggctaga gtttttaaaa taggtcattt tcttctggga
     8641 ggaggatagt ttctctaccg tccatgtcta aaaccagtac tcttggggga taacgagggt
     8701 cgaaaggatg gttaaagtca aaatcaatgg ctgtagggag gtgttgactt gaaaagtgga
     8761 aggtaatctt tccttggtta ttaagcaatt gaaactcgag ttcttcttcc aattcaaaga
     8821 cattttttaa gaaatggtcg ataatatacc aaaaagagtc aatgatgtca tcaggcaagc
     8881 tggtaacaat gccaaaacta gcagaccgca tgtgggtatt ggtaaaagcc atatctctgt
     8941 ctcctttctt ttcccttatc atacagcaaa taggattaaa aatcaagaaa aggtgatttt
     9001 ttgaaaagga ttttaactac agggaaaaag aaggaaaaaa attcccaaaa atctaccgaa
     9061 gttaataggt aaattcccaa attaacttga ttatataact ttcagttact ttgagaagtt
     9121 accgaaaaat atttttcata tctattgact tttaggggtg aaatttggta tgatagtagg
     9181 cggtattgtt taccccattt gaaaggcccc ggaaccttcc aaatactttt cgatgggaag
     9241 gaacacccat caccgtaaac aaaaatcgaa ctatatatag gagaaatcat gaacaaaaca
     9301 acatttatgg ctaaaccagg ccaagttgaa cgtaaatggt acgtagttga cgcaactgat
     9361 gtaccacttg gacgtctttc tgcagtagtt gctagcgtac ttcgcggaaa aaacaaacca
     9421 acatttacac cacacactga tacaggtgac ttcgtgattg ttatcaatgc tgaaaaagtt
     9481 aaattgactg gtaaaaaagc aactgataaa atctactaca ctcactcaaa ccacccaggt
     9541 ggattgaaac aaatctctgc aggtgaactt cgttctaaaa atgcagtacg tttgattgag
     9601 aaatcagtta aaggtatgct tccacacaat acacttggac gcgctcaagg tatgaagttg
     9661 aaagtatttg ttggagctga gcacactcat gctgcacaac aaccagaagt tcttgacatt
     9721 tcaggactta tctaaggaaa ggaacaaata aagtatgtca caagcacaat atgcaggtac
     9781 tggacgtcgt aaaaacgctg ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac
     9841 tgttaacaaa aaagatgttg aagagtacat cccacacgct gaccttcgtc ttgtcatcaa
     9901 ccaaccattc gcagttactt caactgtagg ttcatacgac gttttcgtta acgttgtagg
     9961 tggtggatac gctggtcaat caggagctat ccgtcacggt atcgctcgtg cccttcttca
    10021 agtagaccca gacttccgcg attcattgaa acgcgcagga cttcttacac gtgactcacg
    10081 taaagttgaa cgtaagaaac caggtcttaa gaaagctcgt aaagcatcac aatttagtaa
    10141 acgttaattc gaaagaatta ctatacttat acagagcacc tttcggggtg ttcttttttt
    10201 atactttctt actaaattgg tgcaattgac acagttgttg cgactttagt cgcttacaaa
    10261 tgtggctgca acctgacaag gtcagttgcc tcaaaacgtt aatcaataca attatatcaa
    10321 cgtttcaaag cactcaagag tttacctcat gggtgctttt tttatgtttt ttgaaaaagt
    10381 tcacctcaaa gtttacctta ttttcacctt attgttttag agactgtaag gcaaattcac
    10441 cgacggccat agggactaca ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc
    10501 tatgtattag agcttcagaa atggcttcta agctcattcc tgcttgttta gcgagcgttg
    10561 ctccggtatg acgtagtttg tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga
    10621 tagttttcat cttattattg agatagtcag aatgtaaagg tttattgata ttgcctttgg
    10681 tatctatgta agtaaagatg aattgttctg gattactgat gataccaaac tttgccagtt
    10741 catatttttg ttgttttttc catgaagtca gaagttgaag taagtcatta gaaatagaga
    10801 aaatgggaaa tgtttccaca ataaaacgca tattatcaga tggttaatgc gttttatatt
    10861 tgggtttgag gcttataaaa taggataagc gtactgaaaa cttagatatg acaaacaaaa
    10921 taaaattttt aaaagctaca gagaaacatg gtataatgta tctaaaggag gtagcatatg
    10981 tccttagata tagataaaga aaagatgaca atcatgggaa tagcttttga aaaccgatcc
    11041 gtttttaaga gtgtttggta tgctttaagt acaaatatga ttgaaggatg gcgacctacg
    11101 gttagtgatg ttgaaaaatt acgagatgaa gctcttgctc tggggatgac ttaatgaagc
    11161 gcaactgtta tgagtcttat gactatgttg atccggataa tttatatacc gatccgggtt
    11221 cttcagttct aagaaataag caggaaggaa aaaagcacgt gagcttgaat atcgtatgat
    11281 tgctagtaag agtttgaaat tatttatcaa tcctatctta gttaatagtt taaaagtagt
    11341 ttgtttcaca actgcataag cttagaaaag ttgaaaagtg ataactcttt aataaactct
    11401 tggtttgtta aaagatattt tgtccactac attttttcaa ttgactatta tttgtcatag
    11461 atataacaga tagaacattg cattcagaat aatgaaaaac gcatcaaaaa tggtgcgttc
    11521 tgtttttatg ctaccataaa aggaggaaaa caaattgaaa atttttaagg gagagtttta
    11581 tcgaatctct gtattaacag acaagctagt aaggttagaa tactctcgaa ctggaaattt
    11641 tgaggataga acgacacaac ttatctataa tagagatttt ggccaaattt cgttagatta
    11701 tatcgagaca tcaaacgtac tagatattat gacggactat tttcatctgc actttaataa
    11761 aggagaattt aacgccgaaa atttatttat agaattaaaa ggaaattttg ccgtatatgg
    11821 tagtcgctgg tattttggtg aatctattga aacgttaaaa ggaacagctc ggactctgga
    11881 taaggcagat ggagcaatct cgttagaaga tggaattatt agccgaaatg gtatagcctt
    11941 attggatgat tctcaaggat ttatttggga tgaacaatct ggttatattg agagagaaaa
    12001 tcaaattgac ctgtatttct ttgcctatgg gcatgattat agaggagcaa tcagagactt
    12061 ttaccatttg actggttcaa cacccttgtt gccaagatat gctttaggca attggtggag
    12121 tagatattgg ccttatacgt cggatgaata cttggattta atagacagat ttgaaacaga
    12181 gaaaattcca ttatctatcg gtgtgttaga tatggattgg catataactg acattccagc
    12241 tcgttttgga agtggctgga caggatatag ttggaataga aacttaatac caaatccaga
    12301 acagttattg caacaacttc atgatagaaa gttaaaactc tccttaaatg tccatcctgc
    12361 tgatgggata cgggcttatg aagaagctta tcctcaaatc gcaaaacggt tggggttaaa
    12421 tgtagaacta gaagaacctg ctatttttga tttttttaat ccctctttta gggaagccta
    12481 ctttaaagat gttcattatg agctagaaaa gcagggagta gatttttggt ggattgactg
    12541 gcaacaaggg acacaaggta tgctagatcc actttggctt ttaaaccatt atcactatca
    12601 ggatagttgt aaaaatgcag aaggtggttt gattttatca agatatgcag gtcctggtag
    12661 tcaccgctac cctgttggtt tttcagggga tactattatt agttggaatt ccttaaggtt
    12721 tcaaccctat tttacagcga cagcatctaa tatcggttat agttggtgga gtcatgatat
    12781 cggtggacat atgttggggg attatgacga agagctacaa actagatggc tacagtttgg
    12841 tgtttttagt ccgattactc gattacatag ttctagaagt ccttttaata gtaaagaacc
    12901 ttggtttttt tcagaaacaa catctaagat tatgaagaaa taccttcgtt tgagacatca
    12961 gatgattcct tatctatata ccatgaatgt aaagacacat gaggaaggtg ccccattaat
    13021 cagtccaatc tattatttct atccagagaa tgatgagagc tataatgttc caaaccaata
    13081 cttttttgga acagaactga tggtggctcc cattgtagaa aagatggatt tgacattcca
    13141 atctgcaaaa gtagatgtat ggttccctga aggtgaatgg tatgacttct tttcagagaa
    13201 aaaatacaca ggtggtgtga agttaagtgt ttatagggac atctcgacta cgcctgtgtt
    13261 tgcaaaaagt ggtgcaatca ttcccttggt tggttctgag ataggtatgg gtgttgattt
    13321 acctgaggtt gtagattggt atgtattccc agggaaacaa cattcttttg aaatgcttga
    13381 agatcaaaat ggtcaaagat ataaaacaag attatcaatc gattgggaaa tgggaatggt
    13441 agagttagca ttacaaggag attctagtat cgttccaagc aatagaaaac atagaattca
    13501 ttttaaagga acgaatgtgt ctataattga attgccaaat aagaatgata cagctaaatt
    13561 tgaatggaaa gataataaaa ggacatcttt aaatgacgaa gtttttagac tactaaagac
    13621 agcttctctt ccatatgaat taaaagatag attgttaaat caattcatca atgcgaaaaa
    13681 ctctcatgac ttaatgaata tcttgcatca tcaggataag gaattgagag ggcgtttgtt
    13741 ggaaatgata tttactagcc aaaactaatt gaaataatta gaaagtcatt tgtttagtgt
    13801 atatgaagat tctgtatggt attcgttatc actggtcaca ttgaaaatgt gaaataagca
    13861 cctacaacat agactttaca acacttcatg tttcatatca tggggtgttt ttctatttaa
    13921 gtcaaagcca atcaaaaaat ctcactattc atcaggttaa aggaaaccta atcatagtga
    13981 gattgtgaat tatagtagag tttgtatcgc ctcttcaatt tgttttgggt ctgtttttga
    14041 agaaaagcgt tcaaagactt gcccatcacg accaatgaga aacttagcga aattccattc
    14101 gattcgtttt cctagtgggc cagatttatg gtcttttaac cagacataga gagggtctgc
    14161 ttccttaccg ttgaccttaa tcttggcaaa acgtgggaag gtggtttgaa aatgtaggct
    14221 acagaaggtg ttgatttcct ctgcgctgcc gggtgcttgt cccataaact gattgcaagg
    14281 gaaatccaat atttcgaagc cctgatcttg atagcgttca tagagttctt gaagtctctg
    14341 gtactggggc gttaaaccac atccagtagc agtgttgaca atcaagagaa ctttgccacg
    14401 atagctatcc aagggagttg cttggttgtt ttggttcaaa acggaaaaat cataaagtga
    14461 agtcatgagg gcctcttttc tttttctaca ttgtaacagt ttttactttt ttcgtcgagt
    14521 cggatggaag atattgttga agaataagcc ctcaatatga tagaaaccgt ttacaaataa
    14581 ctttaaaaat ggtatgattt aattaaaccg gtttactttg ttgctataaa tctctaattt
    14641 gagatttagt tcctattgat tttacaatat gtttattgga gtgtatacat gcaaacaaaa
    14701 acaaagaagc tcattgtgag tttgtcttca cttgttttat caggattttt attaaaccat
    14761 tatatgacag ttggagcgga agaaacgact acgaatacca ttcagcaaag ccagaaggaa
    14821 gttcagtatc agcaaaggga tacaaaaaat ttagttgaaa atggtgattt tggtcagacg
    14881 gaggacggaa gcagtccgtg gacaggaagc aaagctcagg ggtggtcagc ttgggtagac
    14941 cagaagaata gttctgcaga tgcctcaact cgagtcattg aggctaagga tggggctatc
    15001 actatctcaa gccctgagaa attaagggca gcggttcacc gtatggttcc tattgaagct
    15061 aagaaaaagt ataaactgcg tttcaagatt aaaacagata ataaagtcgg gattgccaag
    15121 gttcgtatca ttgaggaaag tggtaaggac aagcgattgt ggaattctgc aacgacgtca
    15181 ggaacaaagg actggcagac cattgaagca gactatagcc cgactttaga tgttgataaa
    15241 atcaagctgg agttattcta tgaaacagga actgggactg tttcctttaa ggatattgag
    15301 ctggtagagg tagcagccca gctttctgag gattctcaaa cagataaaca gcttgaggaa
    15361 aagattgatt taccaattgg aaaaaaacat gttttttctc ttgcggacta tacttataag
    15421 gtagaaaatc ctgacgttgc ttcagtcaaa aatggaattt tagaacctct taaggaaggg
    15481 acaaccaatg tcattgtcag taaagatggc aaggaagtga aaaagattcc tttgaagatt
    15541 ctagcctctg ttaaggatgc atacacagcc cgtttggatg actggaatgg catcatcgct
    15601 gggaatcaat actatgattc taaaaatgaa cagatggcca aattaaacca ggaattggaa
    15661 ggaaaggtag ctgatagcct atctagtatt tcaagtcagg cggaccgcac ctatttgtgg
    15721 gaaaaatttt caaattataa aatgtctgca aatctgactg ccacttatcg gaaattggag
    15781 gagatggcca agcaagtgac caatccttct tctcgttatt atcaagatga aactgtcgtt
    15841 cgaacagtca gggattccat ggaatggatg cataaacatg tctacaatcg tgaaaagagc
    15901 attgttggga actggtggga ttatgaaatc ggtacacctc gtgccatcaa caataccttg
    15961 tctctgatga aagaatactt ctctgatgag gaaattaaaa aatatacaga tgtgattgaa
    16021 aaatttgtac cagatcccga acatttccga aagacgactg ataacccatt taaggctcta
    16081 ggtggaaact tagttgatat gggaagagta aaagtaatag ctggtttact gcgtaaagat
    16141 gatcaagaaa tttcttctac cattcgctcg attgagcaag tgttcaagtt ggtagaccaa
    16201 ggtgaaggtt tttatcaaga tggatcctat atcgaccaca ccaatgttgc ctatacgggt
    16261 gcttatggga atgttttgat tgatggcctg tctcaactgt tgccagtcat tcaaaagacc
    16321 aagagtccaa tcgataaaga taaaatgcaa accatgtacc actggattga taaatcgttt
    16381 gctcctttgc tggtgaatgg agaactgatg gatatgagtc gtggacgctc gatcagtcgt
    16441 gcaaatagcg aggggcacgt ggccgcagta gaagtactaa gagggattca ccgaatagcg
    16501 gatatgtctg aaggagaaac caaacaacgt ttgcagagtc ttgtgaagac cattgttcaa
    16561 tcggatagtt attatgatgt ctttaagaat ttgaagactt ataaggatat cagtttgatg
    16621 caatccttgt taagtgatgc aggagtcgca agtgttccaa gaccaagtta cctatctgcc
    16681 tttaacaaga tggataaaac agccatgtac aatgcagaga aagggtttgg atttggcttg
    16741 tcactctttt ccagtcgtac cttgaattac gaacacatga acaaggaaaa taaacgtggt
    16801 tggtatacga gtgatgggat gttctatctt tacaatggcg atttgagtca ctatagcgat
    16861 ggctactggc caacagttaa tccatataag atgcctggta caacagagac ggatgctaag
    16921 agagcggata gcgatacagg taaagtttta ccgtctgctt tcgttggaac gagcaaacta
    16981 gatgatgcca atgcgacagc aaccatggat ttcaccaact ggaatcaaac attgactgct
    17041 cataagagct ggtttatgct aaaggataag attgcctttt taggaagcaa tatccaaaac
    17101 acttcaacag atactgctgc aactacaatc gaccagagaa aactggaatc aagtaatcca
    17161 tataaagtct atgtcaatga taaagaagcc tcccttacag aacaagaaaa ggattatcct
    17221 gaaacccaaa gtgtcttttt agaatcgtcc gattcgaaaa agaatattgg ttactttttc
    17281 tttaagaaga gttcaatcag catgagtaag gctttgcaaa agggagcctg gaagggtatc
    17341 aatgaaggac agtcagacaa ggaagttgaa aatgaatttc ttacgattag tcaggctcat
    17401 aagcaaaatg gagattctta tggctatatg ctcattccta acgtggatcg tgccaccttc
    17461 aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa ataacgaaac ccttcagtct
    17521 gtttatgatg ctaaacaagg agtttggggc attgtgaaat atgatgattc tgtctctact
    17581 atttccaacc aattccaagt tttgaaacgt ggagtctata ccattcgaaa agaaggggat
    17641 gaatataaga ttgcctacta taatcctgaa acccaggaat cagctccaga tcaggaagtc
    17701 tttaaaaagc tagagcaagc agctcagcca caagtacaga attcaaaaga aaaggaaaaa
    17761 tctgaagagg aaaagaacca ttcggatcaa aagaatctcc ctcagacagg agaaggtcag
    17821 tcaatcttgg caagtctagg gttcttgcta cttggggcat tttatctatt ccgtagagga
    17881 aagaacaact aatttgttca tcatctagat gaattacatg aaactgtgga aaatagaaaa
    17941 aatccgaaga aggccaaata tcttcggatt tttcttttaa aaaaggataa gttgatactt
    18001 atcctttttt acttcattat tatgtgacta tagcgttttg aaactagaat agaacgttat
    18061 aactgctaaa agatttctat aaattcattt gattttccta atcaatttgt tcgtatccta
    18121 tttcactcca ctatataagt ccgtctcgct ccgtgaggtg cgcgtcgaag gttataccaa
    18181 aaaaactcca aacgcgatac aataaaggta ttcaatccaa ttgtaaagcg aaaggagaaa
    18241 aaatatggca caaaagactc atagtttatc atacacaaag tggatgtgtt ctatcatatt
    18301 gtgttcaccc ctaagtatag acgaaaagtc atctataatc aatatagaag tagtttaggc
    18361 gaaatatttc atcgcttgtg tagttataaa ggtgttgaaa tgatcgaggg tcacttaatg
    18421 ccagaccatg tacacatgtt agtcagtatt ccgtcgaggc taagtgtttc aagttttatg
    18481 gggtatttaa aaggcaaaag tgcactcatg atgtttgaca aacacgccaa tctcaagtac
    18541 aagtttggga atcggaattt ctgggcggaa ggttattatg taagtccagt agggcttaat
    18601 gaagccacaa ttaagaaata tagtcaagat taaagaaatt atcgagtgga tgatttcttc
    18661 acgagtatga aaatttgaga actagtaaag tatgatatat agtaaaatga aataagaaca
    18721 ggacgaaatc gatcaggaca gtcaaatcga tttttaacaa tgttttagaa gtagaggtat
    18781 actattccag tttcaatcta ctatagcact agataaattg agtgtaaaag aatatgagga
    18841 tccctttagg gatagtggta agtaatacca aagtctctta aagaggcaag tgacgagtca
    18901 agagcaataa ggcttgaaca acgtgaaagc cagcgtcttt aggcgctggc tgatgatttg
    18961 ggcttatagc tctgggataa accacccgtt agacgggtag ttatgatttt atctgagtgt
    19021 aatatactgt tgggcaatct cgctgatgcg gtcaaagttg ccttgggaag cgagtttatt
    19081 gagttcgcca ccaattccaa cggcatctgc accagcagcg aaccattgag ggatgttgtt
    19141 taggccgact cctccggtta ccattacgga aacttgtggg atcggtgcct tgactgcaga
    19201 gatatatgct ggactgagag tactacctgg gaagagtttg atgatttcac taccggcttc
    19261 aagtgcagtc gtgatctctg tgagggtaat acagcctgga atgtacggtg tgctgtagag
    19321 attgcacatt ttcgcagttt cagcatggaa agatggagaa acaacgtaat ttgctccagc
    19381 tagaatggca tctctagcag ttacggcatc aagcacagta cctgcaccga tacaaacact
    19441 ctgatcgtcc tgatacaagt ctacaagttc cttgatgatt tgtcctgcat actgattggt
    19501 ataggcgatt tcaatagctt tgataccgcc cttgatacaa gcaatcgagg cttgtagtcc
    19561 ttcttccttt gtatttcctc gaatgacagc gacaattttc tgttttttta gttcaataat
    19621 cgtatctgat ttggtcatgt aattctccta acgaatgata tcttgtgcat ttgccagtaa
    19681 attttcaata ctagttgcgg aagtggagag atggtctcct ggaagagtgc atttgagagt
    19741 tgcgctcgca actgcaaagt caatggtagt ttttagggag gaatgatgga gtagttggta
    19801 aagggcacca gatataaagg catccccgct accaattcgt tgatagactg cagtttttag
    19861 ttggacagac tcttcaaatc gttcttccag agcataggct tgatagacat ttttgtcttg
    19921 ctcatcacta gatcggaggg tatggaaaat ggccttgaaa ccataggctt cttttaaaag
    19981 tcgcatgcga ttttccacct cttctaggct agcactgtct cttggaaaca tctctagatt
    20041 ttggtcatca atcatgagag gatcaatacc gaagcaatag tcagtaaaac gtgcaaactt
    20101 agaaaattca tacttggctt ctaggactga aatcatcttt gttctcagat tgagatccat
    20161 tgaaacgaca attcctcggc gcttggcttc ttccaagagt aggagaagga tcgcacggac
    20221 ctcttgaccg atagctatgg tgattccact aaaatgaaaa tggctaatcc cctgaaagag
    20281 agaatccata tctagcatgt ttggccgaat ctggctgata ctcgtatgct tacgatcgta
    20341 gaaaacttca ctttgacgac aaccaaagcc gttctccaaa tagtagaggc cgattcgatc
    20401 gccaagccga cagattgaac tggtatcgat ttggtgctgt ttcaagaatg tgagaaaacg
    20461 atctccaatc tcgttggcag ggagtgcggt aaagactttc gttgagatac ccagggcttg
    20521 caaattacaa gcgatgttaa tttctgatcc gccaaaataa gtcgaactgg caacatgatc
    20581 gccgatactg gtggcatcta atggtgagat tcgaattaat ggttcgccaa acagtaatat
    20641 tttcgtcatc cattagttcc tttctggttt agaatagctt tacttggcta atacttcttt
    20701 caaataagca gcgacttcat catcttggca gttttcaaag aagtattctt ggaagtattt
    20761 gccagagatg gtgtctttga ggaagtcttg gtcgattgtt ttaaggatgg tcatcaaatc
    20821 attgtgggtg atttgtttca cctcgtttaa gatacgagcg ttacgttgtt cagggattac
    20881 acgttctctt gggtagccac cgcccatttc ttcagcaaat aagcgttcaa acatcaattt
    20941 gagggtcagt tctgcccccc agccaaatcc tttggcataa gggatagaca aggcgttacc
    21001 accattgatt tgagaataaa ggtaagcgtc agttgggtcc actgctagac cacagacaac
    21061 accagggaag ctgtttaaag caagcatagc ccctacaccc gtaccacagc cggtaacaac
    21121 aaagtcaact gcctttgtat ttaaaaggat ggcagccatt agtccgttct gcacataagt
    21181 taattgactt tctccttctt ctccacgcat accatagtta aataattggt agtctttttt
    21241 atctgtcgct tcttttagac tatcgtaaat aatgtgattc ttgctagctt gactattttc
    21301 attgattaat gcgattttca taagatcttc tttctatttt tactcaggtt gttttccgat
    21361 gtaggctaag ataccgccat ctacatatag gatgtggcca ttgacaaaat tgctggcatc
    21421 actagcgaga aagacagcag ggcccatcaa atcttcagga tttccccaac gtgcagcagg
    21481 tgtttttgca atgatgaact ggtcaaatgg gtggcgagaa ccatcttctt gcaactcacg
    21541 aagaggtgct gtttgaggag tggcaatata acctggtcca attccgttac attggatatt
    21601 ggctccaccg tattcagacg caatgttgcg ggtcaacatt ttcaagcccc ctttagcagc
    21661 agcataagcg ctaactgttt cacgtcccag ttcgctcatc atcgaacaaa tattgataat
    21721 ctttccatgc cctttcttta tcatagaagg aataactgcc tttgaaacga taaatggtgc
    21781 gtttaagtca atatcgatga ccttacggaa atcagcggcg ctcatttcgc acattggaac
    21841 tcggcggata ataccagcgt tattaacgag gatgtcaatg acaccaacct cttgttcgat
    21901 ttgcttgacc atggcttgga taccgtcctc gtctgtcacg tcacagacat atccatgggc
    21961 ttggatgcca acttcacgat aagcttcaat ccctttattg accagatctt gattgatatc
    22021 gttaaagaca atagtagcgc cggcttcagc gtaggatttg gcaatagcaa atccaattcc
    22081 ataagaagcg ccggtgatga gagcaatttt tccttttaaa gaaaactgct caattgagaa
    22141 tgatgtattt gtcatttgat acttcctttc aaatttgtta agacttctct ataatcaaat
    22201 tatattctag taaaccggtt ttgtcaataa ataaatattt ttatttataa aaagatttat
    22261 ttcccttaaa aatggaagat tttgaaattt ctgcctatta aaatggttaa aaagataatg
    22321 aaagcgctaa tattttttta aaaaaactat tgacaagata aaaataaagg attacaatgg
    22381 ggaatataaa gtaaaccggt aaacctaaac aagaaaggag aaaagatgaa aattgtactt
    22441 gtagggcatg gacattttgc tacagggatt tatagttctt tacaattgat tgcaggcaat
    22501 caagaaaatg tggaggcaat tgactttgtg gaaggaatgt cagcagatga actcaagcaa
    22561 aaaatcttac ttgcaatttc aaatgaagaa gaagttttaa tcctaagtga tctcttggga
    22621 ggatcgccat tcaaggtttc ttctaccata atgggagaaa atccagccaa aacaatgaat
    22681 gttctctcgg gtttgaactt agccatgtta atggaagcag tctttgctag aatggctcat
    22741 agctttgatg aggttgttaa taaatcagta gtggcggccc agggcggagt cgtaaatggt
    22801 aaagaattgt tttcaacgga tgcagaggaa gaggaagaag atttcgaatc gggtatttaa
    22861 agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct gagcgcttct
    22921 tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag gttattcggc
    22981 agttagaact caaccttgac tatttcaagg aagatttccc gacgccagct acctttgata
    23041 atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca ggagaactgt
    23101 ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat aaaaatgttc
    23161 tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat ctcggcttct
    23221 tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag gctagagaag
    23281 caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt ggttttattc
    23341 aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac tgcttgctca
    23401 atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac tacgatattg
    23461 cagaaagcca tttctatgct tcagctaata atgtaatccg tgatgacgct tcgtccttcc
    23521 acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg agacaagggt
    23581 atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt attcctttga
    23641 cttatcgtca cttaaaagac gagttctgct ttgacttgtt taagggtgtg accaattatt
    23701 tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt aatgatggta
    23761 gtgatcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt catgaaatgc
    23821 taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct atgcatgcca
    23881 tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt gggacaagtc
    23941 tcctccacgg tgtgtactca tggcattcag gtaaaggagt agatgaaggc aatatctggg
    24001 gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac ctatattggt
    24061 aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga acggttgatt
    24121 catggacaag gacaactttg ggtaaaatac ctaggttgta atacggtcat tgttgccaat
    24181 gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt gccagactca
    24241 gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa ggctaatcct
    24301 gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt ggtagaaggt
    24361 ggtgtcccta tcaaagaaat caatattggg aacattcaca atgcccctgg taaagagcaa
    24421 gtgacacgct ccatcttcct gggtgaagag gacaaggcag ccctcaagga attaagccaa
    24481 actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg agctgttcaa
    24541 gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat gtatttcaag
    24601 cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta ggaatttaca
    24661 ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat ctgcctactg
    24721 ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt ggtgctggag
    24781 gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg gctatcacta
    24841 gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt gctgtggcga
    24901 ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa acggcgatga
    24961 agcacttgaa aaaccataat ttgaagaaat ttaagttcac tctaaatgca acaatttggt
    25021 tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg gataccttgt
    25081 tgaaactcgt agactacatt ccaccggtat tacttacagg tttgacagtt gctggtaaaa
    25141 tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa gagttgattc
    25201 cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca attggtattg
    25261 caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa acagcggatc
    25321 atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa acgtgattat
    25381 cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag taactatcaa
    25441 gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg agaggatcag
    25501 gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa cccacacttc
    25561 ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc ggcaaaagaa
    25621 acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga ttctctttct
    25681 caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca agaaggcttg
    25741 gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc gattaaattg
    25801 tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact aagcgaacag
    25861 atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc tggtttggca
    25921 gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt taaagcagac
    25981 gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc agctcttcta
    26041 ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg gacaacatat
    26101 aaactcgtta ttttaacagt tatcatcgga attatcggaa gctggcttaa gattatagct
    26161 taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt ccccttttac
    26221 tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagatg gagcaacgac
    26281 aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct ggaattcatg
    26341 gaaaaatcat ttctatcaaa gatgacttgg tctccttgca gattgcaaaa ggtgtggtca
    26401 tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt aagtagttct
    26461 ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga atcgatggaa
    26521 accaatgtcg tgattatatc ttgtcccact gttcaaaaga ctatgagaaa gtcaagagtt
    26581 cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat atggagcctt
    26641 gttcaaaaat ccatcaaatc cagccgatgg tatgggatca agtatttgaa gatgatccag
    26701 aatggtctta tatgctcaat cgacaagaat atctcttgca gtttatgata gggtatgtgg
    26761 tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat tggattgagc
    26821 aggtgagaga attttctcct caatccttga tgactagaac cttggatacg ggtattcgtt
    26881 cctttacttg gttgaaacta ctcttgcttc tcttgaaatt tgacttgcta gaggagaaag
    26941 aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa agctactatc
    27001 gcgccaagta cacccttagt aactggggga ttttacaaac aattccgatg cttgctatct
    27061 atcatttctt ttcagataag atggacctag aagaagctta ccattttgct tcagaggagt
    27121 tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa cagtcgattc
    27181 tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt ccagacttgc
    27241 aagatagtta ccaagagttg ctggaaaaga tggcgaccta tattcaaatg atgacaggct
    27301 tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca gaaattttga
    27361 gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat gttaaagtcg
    27421 atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag gaatttgaaa
    27481 agagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc tgcattaagg
    27541 atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat agccatagtg
    27601 acgagaatag tttttgctta cagtatcaag gccaacctat tttcatagat gctgggcgtt
    27661 attcttatcg ggagatataa gaacgttatc tcttaaagag tgcttggagt cattcgacct
    27721 gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat gaatactatc
    27781 ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt gagggggctt
    27841 attggtcagc agaacctgat ttgccttatc ttcacagaag aaaaatcctc atgttggtag
    27901 aggatgtctg gctcttggtg gatgacatca ggtgtcaagg tcagcatgag gcgttgactc
    27961 agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag ttgagactat
    28021 ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac aatgagcttg
    28081 aaagaagtag caaactcacc aagcgccaat tctttgagaa tcagatgctg gattatacca
    28141 tcattgcgca tgaaagtttt gaaatcatcc gtcattctgt ctaccagaca gatgatcgtg
    28201 aagtggaaaa tgctctggct tttgaagtga aaaatgatga aacagacaag ctgattctgt
    28261 tattaagcga ggatattggt gtaggtgaaa aattgtgcct cgttgacgga acaaaaatgc
    28321 gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg cagtgctaga
    28381 aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt gttttagatt
    28441 ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga aaacaaccgt
    28501 gtcattttac ctaaatggga aatatgaaaa aatgtcccaa gagacacgtg aaaagattga
    28561 aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct taaactccaa
    28621 acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct caaaccaaat
    28681 tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga taggaaatag
    28741 taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct tgggagtaga
    28801 cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca tcgatgagaa
    28861 aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta gctgggttaa
    28921 aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa aaggttatga
    28981 acattttctc ttgattacag cggatacgag tcgtttgagt actcggattg agcgggcaag
    29041 tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa ccattgaaga
    29101 taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg atcccgatga
    29161 aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta ccgttatcaa
    29221 agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata cggagtggac
    29281 ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg aaggacaaca
    29341 ggctacaaag attttgattg accagattga aggccgcaat caagaagaaa ggcaacaagt
    29401 cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa aatgacttgc
    29461 gatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga ttatttgcct
    29521 atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc tacttcttta
    29581 actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac gactaggaat
    29641 attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat gaggagaaag
    29701 aagagggctg cgttgaggac agatatccgt tttgattgta ttttctcaag tcctttattg
    29761 agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc tcctgaaata
    29821 agggcgaaga aaaggaaaat actgataaaa acatgaatga tcagtagtct agctagtgat
    29881 ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa gtgagtcgac
    29941 aatatgcatc atcactccga aaaagaaagc tcccagtata gttttaaaaa tatgttttgt
    30001 atttagaaga gaagtgataa aatttggatt atcacttgtt agggtatcaa tgggtggaat
    30061 tataaaaaat atcactattc cataaatcga acctgctttc agaccaggat gacgtaactg
    30121 tttcttttct tttttcatga gtttcctcct aatcattatc ctgatctttc ttggcttttg
    30181 caatgcgacg ggagatgagg aactgtatgc ttgccccgaa gaagatagaa ccgagaatgc
    30241 ttgatacacc atttcttata gtgagaagag actgaaaata gtcctgacct tcacctatga
    30301 gtatatcgag aagaggagtt ataaaaaata tccatagacc aaagaacaaa cctgctttca
    30361 gacctgggta gcgaagttgc ttgctttctt tctcattcag catatctggt tcaatgactg
    30421 tgatgcctgt ttttttcatt tggtaggtga catagccagc agcgatgagg gcaatcacta
    30481 aaatcagagg aggatagatt agagccactt cttgaggata tttataggcc agaaggagtg
    30541 gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg ttgccgatac
    30601 gatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat gtgcgtttga
    30661 tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa aaatcttcct
    30721 cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga cagagttcca
    30781 gggttggatt gtacttgtcg ttttcaatca tattgatggt ctgtctcgag acaccgatat
    30841 ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc acacgattca
    30901 tctggtctcc tttctgattt gtgtcgtata tatttgacta tattatattc ttttaaacat
    30961 aaagtgtcaa gtatttttga catatttttt gaagaaatag tagcgctctt gtctgatttg
    31021 tctgactagt gcaagctggt cggatttgtg gtaaaataga taagatatga caaaagaatt
    31081 tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa agcccgacgg
    31141 tatctacgtt gatgcgactt tgggtggagc aggccatagc gaatatttat taagtaaatt
    31201 aagtgaaaaa ggccatctct atgcctttga ccaggaccag aatgccattg acaatgcgca
    31261 ggaacgcttg gcaccctaca ttgagaaggg aatggtgacc tttatcaagg ataacttccg
    31321 tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa tttgttatga
    31381 cttgggagtg tctagtcctc aattagacca gcgtgagcgt ggtttttctt ataaaaagga
    31441 tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg aagtggtgaa
    31501 caattatgac tatcatgact tggttcgtat tttcttcaag tatggagagg acaaattctc
    31561 taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg agacaacgac
    31621 tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga agaaggggca
    31681 tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac tgggggcggc
    31741 agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa tttcagtgat
    31801 tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag cttcaacagt
    31861 tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga tggaattggt
    31921 gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc gctcgcactc
    31981 agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa
    32041 atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg tgtggaaaaa
    32101 gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat tatttttatg
    32161 cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa
    32221 aagaaaaccg aattggacga tgccaagcaa gaggtcaatg aactattacg tgcagaacgt
    32281 ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat tagaatagcg
    32341 gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa tcggaaatcg
    32401 ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt ctttgttttt
    32461 gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt tggaacagat
    32521 ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc caaacgtggg
    32581 actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta taatgtctat
    32641 gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt agaaaaaaca
    32701 caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga atcctatgta
    32761 agagagcaac tctcgcaacc taatctcaaa caagtttcct ttggagcaaa ggggaatggg
    32821 attacctatg ccaatatgat gtctatcaaa aaagagttgg aaactgcaga ggtcaagggg
    32881 attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc ttctagtttt
    32941 atcggactag ctcagctaca tgaaaatgaa gatggaagta agagtttgct gggaacctct
    33001 ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat tacctatgaa
    33061 aaggatcgtc tgggcaatat tatacccgga acagaacaag tttcccaaca aacggtggac
    33121 ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga aacccagatg
    33181 gatgcttttc aagagaaggt aaaaggaaag tacatgacag caactttggt cagtgctaaa
    33241 acgggggaga ttcttgcaac gacgcagaga ccaaccttcg atgctgatac taaggaaggg
    33301 ctgactaagg attttgtttg gcgtgatatc ctctatcaaa gtaactatga gccagggtca
    33361 accatgaagg tcatgacgct cgctgctgct attgataata ataccttccc aagtggagaa
    33421 tacttcaata gcagtgaatt aaaaatagcg gatgtgacga ttcgagattg ggatgttaat
    33481 gatggtttga ctactggtag gatgatgact ttcttacaag gtttcgctct ctccagtaat
    33541 gttggaatga gtctacttga acaaaaaatg ggagatgcta cctggcttga ttatcttaat
    33601 cgctttaaat ttggtgttcc gacccgtttc ggtttgacag atgagtatgc tggtcagctt
    33661 cctgcggata atatagttaa cattgcgcaa agctcatttg ggcaagggat ttcagtgacc
    33721 cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat gctggagcct
    33781 aaatttatta gtgccattta tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa
    33841 attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa catggttttg
    33901 gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa gccaactgta
    33961 actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc tgacgagaaa
    34021 aatggtggtt atctagtcgg gttaaccaac tatattttct cggctgtatc gatgagtccg
    34081 gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca ttattcaggt
    34141 attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat gaaagactct
    34201 ctcaatcttc aaacaacagc taaagccttg gagcaagtaa gtcaacaaag tccttatcct
    34261 atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg tcgcaatctt
    34321 gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc tgaagaaggg
    34381 aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagcaga ggaggttcca
    34441 gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct caatatagaa
    34501 cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc taacacagct
    34561 atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta tttctatcag
    34621 tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta tccaatttta
    34681 tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc atcaggcaaa
    34741 agctgggact cctacaatgg gaggtttggt tttcttgttt acttctgttt tggttgcttt
    34801 ctttttcgcc ctatttagta gccaattcag caataatgtg ggaatgattt tgttcatctt
    34861 ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc gtaaaatcaa
    34921 tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag ttatcttcta
    34981 tcttttctat gagcgtgggg gcgatatgct ttctgtcttt ggttatcaag tgcatctagg
    35041 gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg cagtaaactt
    35101 gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt ctgcctatgg
    35161 agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg ccatgattgg
    35221 tggtttgctc ggtttcttca tctttaacca taagcctgcc aaggtcttta tgggagatgt
    35281 gggaagtttg gccctaggtg gaatgctggc agctatctct atggccctcc accaagaatg
    35341 gactctcttg attatcggaa ttgtgtatgt ttttgaaaca acttcggtca tgatgcaagt
    35401 cagttatttc aaactgacag gcggtaaacg tattttccgt atgacgcctg tacatcacca
    35461 ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga aggttgactt
    35521 cttcttttgg ggaattgggc ttctagcaag tctcctgacc ctagcaattt tatatttgat
    35581 gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca atgaaaatca
    35641 aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg aaactagaat
    35701 agtacaccgt aacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt
    35761 cttgttctta tttcatttta ctatacagtt ttgagatggt tgatagaact gacgaagtca
    35821 gctcaaaaca cggttttgag gttgtagaca aggcgaagct gatgtggttt gaagaggttt
    35881 tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa tgcttgacct tttctgacta
    35941 atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt atttaaagta
    36001 aaatagaaag aggtggggtc tatgtttcat ctagaaatct tcagaagtaa agatagtcta
    36061 ctcctgcttg aaaaagaaaa accagaaata gtacataggg tagcggttta actagtctaa
    36121 attttttaaa gaaaaggtca aagatagtca atatcagtaa taataaataa caaaaagagg
    36181 taaagaatat gaacaacaat tttaataatt ttaacaacat ggatgattta tttaaccaat
    36241 tgatgggtgg tatgcgagga tacagttctg aaaatcgacg ttacttgatt aatggacgtg
    36301 aagtgacacc tgaggaattt gcttactatc gtgcaactgg tcaattgcca ggaaatgcag
    36361 aatctgatgt gcaaatgcaa caacaggctt caggtatgaa acaagatggt gtccttgcta
    36421 aactgggtcg aaacttgaca gcagaagcgc gtgagggcaa gctggatcct gttatcggac
    36481 gaaacaagga aattcaagaa gcatctgaaa tcctctcacg ccgtaccaag aacaatcctg
    36541 ttttagtcgg agacgcaggt gttggtaaga cagccgttgt cgaaggccta gcgcaagcga
    36601 ttgtgaacgg cgatgtccca gctgctatta agaacaagga aattgtttcc attgatatct
    36661 caggtcttga ggctggtact caataccgtg gtagctttga agaaaatgtc caaaacttag
    36721 tcaatgaagt gaaagaagca gggaatatta tcctcttctt tgatgaaatt caccaaattc
    36781 ttggtgctgg tagcactggt ggagacagtg gttctaaagg gcttgcggat attctcaagc
    36841 cagctctctc tcgtggagaa ttgacagtga ttggggcaac aactcaagac gaataccgta
    36901 acaccatctt gaagaatgct gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc
    36961 cttcggcaga gaatactttt aaaattcttc aaggaattcg tgacctctat caacaacacc
    37021 acaatgtcat cttgccagac gaagtcttga aagcagcggt ggattattct gttcaataca
    37081 ttcctcaacg tagcttgcca gataaggcta ttgaccttgt cgatgtaaca gctgctcact
    37141 tggcggctca acatccagta acagatgtgc atgctgttga acgagaaatc gaaacggaaa
    37201 aagacaagca agaaaaagca gttgaagcag aagattttga agcagctcta aactataaaa
    37261 cacgcattgc agaattggaa aagaaaatcg aaaaccacac agaagatatg aaagtgactg
    37321 caagtgtcaa cgatgtggct gaatctgtgg aacgaatgac aggtatccca gtatcgcaaa
    37381 tgggagcttc agatatcgaa cgtttgaaag atatggctca tcgcttgcaa gacaaggtga
    37441 ttggtcaaga taaggccgta gaagctgtag ctcgtgctat ccgtcgtaac cgtgctggtt
    37501 ttgatgaagg aaatcgccca atcggcagct tcctctttgt agggtctact ggggttggta
    37561 agacggagct tgctaagcaa ttggcactcg atatgtttgg aacccaggat gcgattatcc
    37621 gtttggatat gtctgaatac agtgaccgca cagctgtttc taagctaatt ggtacaacag
    37681 caggctatgt gggttatgat gacaatagca ataccttaac agaacgtgtt cgtcgcaatc
    37741 catactctat cattctcttg gatgaaattg aaaaggctga ccctcaagtt attacccttc
    37801 tcctccaagt tctagatgat ggtcgtttga cagatggtca aggaaataca gtaaacttca
    37861 agaacactgt cattattgcg acctcaaatg ctggatttgg ctatgaagcc aacttgacag
    37921 aagatgcgga taaaccagaa ttgatggacc gtttgaaacc cttcttccgt ccagaattcc
    37981 tcaaccgctt taatgcagtc atcgaattct cacacttgac taaggaagac ctttctaaga
    38041 ttgtagattt gatgttggct gaagttaacc aaaccttggc taagaaagac attgacttgg
    38101 tagtcagtca agcggctaaa gattatatca cagaagaagg ttacgacgaa gtcatgggag
    38161 ttcgtcctct ccgtcgagtg gttgaacaag aaattcgtga taaggtgaca gacttccact
    38221 tggatcattt agatgctaaa catctggaag cagatatgga agatggcgtt ttggttattc
    38281 gtgagaaagc ctaagataga attttgagga taaaaaagaa ggagccagct gaaaaaaact
    38341 ggttcctttt gaggtacgac gggcatgtcg tatagtaggt tgaaactaga atagtacaca
    38401 tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgaacgattt gtcctgttct
    38461 tatttcattt tactatatat ctgaatatct gaggtgtaag tcctcggtgg gcacccacta
    38521 ccggtgaacc caatagcgat tcccaagcct gactatcgtg aggtagtgga ttaaaacggt
    38581 ctggggatag accgttttaa gtctgacgct ggaaataaga atcgtcagag gaagggatag
    38641 cgaaatcgtg gctttacgaa caggaacgtg atagtaaggc gtatatagcg gataaggggg
    38701 tctcaaactc taaagttcaa aaaggtagtc gtaacctata tgcgtaaatc acgagagcaa
    38761 ctgaatttgt tcattcgagg atggataaac tatttctcat tgggaaatat gaaaagtata
    38821 gtcgccagca tagatgagcg cttgcgtact cgcctacgag tgattatctg gaagcaatgg
    38881 aagaagaaat cgagacgatt atggggattg cttaagttag gagttcctaa atggatagca
    38941 gataaggtat ctggctgggg cgaccattat caattagtag ctcagaagtc ggtacttaaa
    39001 cgtgctatat caaaaccagt cctggaaaaa cgtggactgg tttcgtgttt ggattattac
    39061 cttgaacgac atgcgttaaa agttagttga accgccgtat gccggacggc acgtacggtg
    39121 gtgtgagagg ggctagagat tatcccctac tcgattttaa atcacatgac gttcaaaggc
    39181 atcatctgaa atcccttgtt ccaagatgag ttttgcccat tctttagcag agaagaggct
    39241 gtggtccttg tagtttccgc aagattcgat ggttgtccct gggacatctt cccaagtagt
    39301 agtttcagcg atttccttga gcgaatcctt gataacagct gcgattttag cactggtgtg
    39361 acgtccccac ataatcatgt ggaagcctgt gcggcaacca aatggtgaac agtcaatcat
    39421 gccgtcaatg cgggtacgga tgagtttggc taagaggtgc tcgatagtgt gaaggccggc
    39481 agtagggata gagtcttcgt ttggttgcac caagcgaata tcataattgg agatgatgtc
    39541 tccttttggt cctgtttctt ccccaatcaa gcgaacatag ggtgctttga caatggtgtg
    39601 gtcaagttca aaactttcga caataacttc ttttgacatg gtaaatcctt tcagttttct
    39661 tctctcatta tatcataaag gttgctcctg agacagagag aaaacctctc cgaggctgga
    39721 gaggttgaaa tctttactta cgatataagc ggtcgtattg gtagtatggg tcaaaggtta
    39781 cgttgatacc cagtttacga aggacattct tgtcttcatc agtcaagatg atggttgagt
    39841 gggcttcgct tcctttgagg ttgccgagtt cttccatagc gcgggcagca tcaggatttt
    39901 ctgtagctgt gatagcaagt gcaatcagga tttcatttga atgaaggcgt ggattgcggc
    39961 taccgagatg atcgatttta agaccttgga ttggcttaac aacttccggc tcgattaatt
    40021 ttacttcttt agcgatgtca gctgattttt tgatggcgtt gatcaaggca gcggctgtag
    40081 ggccaaagag ttctgagttc ttaccagtga cgatttcccc atttggcaat tcaaaggcta
    40141 gggctggtcc accagtttct tctgcttttt ggcgcgcaac gacagcaacc ttacggtctg
    40201 caggtgtgat accgaggtcg ttcatgagca actcaatttt cttgacggca gcttcgccaa
    40261 ctttttcagc tttgaagtca agaactgttt gatagtaacg gcggatgatt tcttgtttag
    40321 aagcttcgac agcagcctcg tcatctgtaa tagcgaaacc aaccatgttg acacccatat
    40381 ctgtcggtga agcgtatggt gattttccga gaatacgttc caacatgcgc ttgagcactg
    40441 ggaagatttc gatatcacgg ttgtagttga cagtggtttc tccataggtt tgaagatgga
    40501 aggggtcaat catgttgaca tcatcaaggt cagctgtggc agcttcataa gccaagttaa
    40561 ctggatgatg aaggggaaga ttccaaacag ggaaggtttc aaatttagcg tagccagatt
    40621 tgatgccatt gatttggtcg tggtacatat tggacataca cgttgccaat tttccagaac
    40681 cgggtccagg agcggttacg acaatcaagt tgcgactggt tttgatgtag tcgtttttgc
    40741 ccatgccttc tggggaaatg atgtgatcca tatccgtcgg atatcctttg attggataat
    40801 gaagataaga atcaattccg tttttctcaa gttgattgcg gaaggcatct gcagcgggtt
    40861 ggccagcgta ttgtgtaatg acaacggaac caacaaaaat ccctaattca ttgaatttgt
    40921 caatcaaacg aagaacttct tggtcataag aaatgcctaa gtcgccacgt gctttggaat
    40981 gttcaatgtt gctagcatta atggcaatca caacctcaac ctgctctttc aattcttgca
    41041 agagcttgat tttgttgtca ggttcataac caggaaggac acgagcagcg tggaaatctt
    41101 ctaacatttt accgccaaac tctaagtaga gcttgccgtc aaattggtta atgcgctcca
    41161 aaatatggtc gcgttgtaaa ttcaaatatt gttcagaact aaaagcttgt tttttcattt
    41221 ttttacctct ggactctatt ataataaaaa attggaagtt aggaaactac ggagctaaaa
    41281 aagaaattaa aaagattaag caaacgcttg cacaaaattt taaaaagtgc tatcatatac
    41341 tatagattat taaaataatg aggtaagaag atgcaagaaa aatggtggca taatgccgta
    41401 gtctatcaag tctatccaaa gagttttatg gatagtaatg gagatggagt tggtgatttg
    41461 ccaggtatta ccagtaagtt ggactatcta gctaagctag gaatcacagc gatttggctt
    41521 tctcccgttt atgacagccc tatggatgat aatggctacg atattgctga ttatcaagcg
    41581 attgcaacga tttttggaac catggaggat atggatcaac tgattgcgga agctaagaag
    41641 cgtgacattc gtatcatcat ggacttggtg gttaatcata cctcagatga acatgcttgg
    41701 tttgtcgaag cctgtgaaaa tactgacagc cctgagcgag actactatat ctggcgcgat
    41761 gaacccaatg acctagattc tatctttagt gggtctgctt gggaatacga tgaaaagtca
    41821 ggtcaatact atctccactt tttcagcaaa aaacagccgg atctcaactg ggaaaatgaa
    41881 aaacttcgcc agaaaattta tgagatgatg aacttctgga ttgataaagg tattggtggt
    41941 ttccgtatgg atgttattga catgattggc aaaattcctg acgagaaggt agtcaataat
    42001 ggtcctatgc tccatcccta tctcaaggaa atgaatcagg cgacctttgg agataaggat
    42061 ctcttgacag taggggagac ttggggagca acgccagaga ttgccaagct ctactctgat
    42121 ccaaaggggc aagaattgtc tatggtcttc cagtttgaac atatcggtct tcagtatcag
    42181 gaaggtcagc ctaaatggca ctatcaaaaa gagctgaata tcgctaagtt aaaagaaatc
    42241 ttcaacaaat ggcagacaga gttaggagtt gaggacggct ggaattccct cttctggaac
    42301 aaccatgacc tccctcgtat tgtctcaatc tggggaaatg accaagaata ccgcgaaaaa
    42361 tctgccaaag cctttgcaat cttacttcat ctcatgagag gaactcctta tatctaccaa
    42421 ggtgaggaga ttgggatgac caactatccg tttgaaacac tagatcaagt agaagatatt
    42481 gaatctctca actatgcgcg tgaggctctt gaaaaaggtg ttccgatgca agaaatcatg
    42541 gacagtatcc gtgttattgg acgtgacaat gcccgtaccc ctatgcaatg ggacgagagc
    42601 aaaaacgctg gtttctcaac aggtcaacct tggttggcag ttaatccaaa ttacgagatg
    42661 atcaacgtcc aagaagcgct ggcaaatcca gattctattt tctataccta tcagaaactg
    42721 gtccaaattc gcaaggagaa tagctggcta attcgagctg actttgaatt gcttgatacg
    42781 gctgataagg tctttgctta tatacgtaag gatggcgacc gtcgcttcct agttgtggct
    42841 aacttgtcca atgaagagca agacttgaca gtagaaggaa aagtcaaatc tgtcttgatt
    42901 gaaaacaccc tagctcaaga agtctttgaa aaacaaatct tagttccatg ggatgctttc
    42961 tgtgtggaat tactataaat attttttgca gaaaaattta aaattgaaat cgtataaaaa
    43021 caagggagga ctgtataaaa ggcagaaatc ctttgttttt tataaccaag gtttataaac
    43081 cttcattctc gaaattcaat taactttaca aattcccact attaaggaga aagaagacga
    43141 acataaagaa gcgtatcctt agtgcaggcc tgacttttac atctgctttg cttttagctg
    43201 cttgcgacca atcaggttca gatacaaaaa cttactcatc aacctttagt ggaaatccaa
    43261 ctacatttaa ctatctatta gactattacg ctgataatat agtcaattga aacaagaaca
    43321 agacaaaaga gcctcataaa aggtattgca acttggtaat acctttttga ggtgcttttt
    43381 gatatgagcc catgttttct caataggatt gtactcaggt gagtagggag gaagaggtaa
    43441 aagtttatgc ccaaactctt cgcataaaag ttctagcttc cccattctat ggaatcttgc
    43501 attatccata ataataaccg atggtgtggt taatgttggt aagaaaaact tctgaaacca
    43561 tacttcaaaa aagtcgctcg tcatcatctc ttcgtaagtc attggagcga ttaactcacc
    43621 atttgttaga cctgcaacca aagaaattct ctgatatctt cttccagata ctttgcctct
    43681 tattaactga ccttttaatg agcgaccata ttctcgataa aaataagtat cgaatcctgt
    43741 ttcgtcaatc taaacaggtg ctaggtgctt taaactatta aaattcttaa gaaataaggc
    43801 tacttttctg ggtcttgttc ataattagat tgaaactaga gtagtagacc tctgcttcta
    43861 aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcatgttct tatttcattt
    43921 tactatattt ttgtttcgcg ggaagtctac taagatactt aaagatgcag atagtaaaaa
    43981 aagatgcaga tagtaaaaaa atgtagacat taccgtaaaa aagtgatata atcataagat
    44041 gttcaatgta taggtgttaa tcatgagtag acgttttaaa aaatcaggtt cacagaaagt
    44101 gaagcgaagt gttaatatcg ttttgctgac tatttattta ttgttagttt gttttttatt
    44161 gttcttaatc tttaagtaca atatccttgc ttttagatat cttaacctag tggtaactgc
    44221 gttagtccta ctagttgcct tggtagggct actcttgatt atctataaaa aagctgaaaa
    44281 gtttactatt tttctgttgg tgttctctat ccttgtcagc tctgtgtcgc tctttgcagt
    44341 acagcagttt gtgggactga ccaatcgttt aaatgcgact tctaattact cagaatattc
    44401 gatcagtgtt gctgttttag cagatagtga gattgagaat gttacgcaac tgatgagtgt
    44461 gacagcaccg actgggactg ataatgaaaa cattcaaaaa ctactagctg atatcaaatc
    44521 aagtcagaat accgatttga cggtcaatca gagttcgtct tacttggcag cttataagag
    44581 tttgattgca ggagagacta aggccattgt cttaaatagt gtctttgaaa atatcatcga
    44641 atcggagcat ccagattacg catcgaagat aaaaaagatt tataccaagg gattcactaa
    44701 aaaagtagaa gctcctaaga cgtctaagga tcagtctttc aatatctatg ttagtggaat
    44761 tgatacttat ggtccgatta gttcggtgtc gcgttcagat gtcaatatcc tgatgactgt
    44821 caatcgagat accaagaaaa ttctcttgac cacaacgcca cgtgatgctt atgtaccaat
    44881 cgcagatggt gggaataatc aaaaagataa attgacccat gcgggcattt atggagttga
    44941 ttcgtccatt cacaccttag aaaatctcta tggagtggat atcaattact atgtgcgatt
    45001 gaacttcact tctttcttga aaatgattga cttattggga ggggtagatg ttcataatga
    45061 tcaagagttt tcagctctac atgggaagtt ccatttccca gtagggaatg tccacctaga
    45121 ctctgagcag gctctaagtt ttgtacgtga acgctactca ctagccgatg gagaccgtga
    45181 ccgtggtcgc aaccaacaaa aggtgattgt ggctatcctt caaaaattaa cttcgagcga
    45241 agcgctgaaa aattatagta ggatcattga tagcttgcaa gattctatcc aaacaaacat
    45301 gccacttgag accatgataa acttggtcaa tgctcagtta gaaagtggtg gaacgtacaa
    45361 agtgaattcg caagacttga agggtatggg acggacggat cttccttcct atgcgatgcc
    45421 agatagtaac ctctatatga tggaaattaa cgacagtagc cttgcatctg tcaaaactgc
    45481 tattcaggat gtgttggagg gcagatgaaa tgattgatat tcattcgcac atcgtctttg
    45541 atgtagatga tggtcccaag tcaagagagg aaagcaaggc tctcttggca gaatcctaca
    45601 ggcagggggt gcgaaccatt gtctctacct ctcaccgtcg caagggcatg tttgaaactc
    45661 cggaagagaa gatagcagaa aactttcttc aggttcggga aatagctaag gaagtggcga
    45721 gtgacttggt cattgcttac ggggctgaaa tttactacac atcagatgtt ttggataagc
    45781 tggaaaaaaa tcggattccg accctcaata atagtcgtta tgccttgata gagtttagta
    45841 tgaacacccc ttatcgcgat attcatagtg ccttgagtaa aatattgatg ttgggaatta
    45901 ctccagtcat tgcccacatt gagcgctatg atgcacttga aaataatgaa aaacgcgttc
    45961 gagagctgat caatatgggc tgttacacgc aagtaaatag ttcacatgtc ctcaaatcca
    46021 aactttttgg agaacgttat aaattcatga aaaaaagagc tcagtatttt ttggagcgtg
    46081 acttggttca tatcattgca agtgatatgc ataatgtgga cagcagacct ccccatatgg
    46141 cagaagcata tgaccttgtt tcccaaaaat acggagaagc gaaggctcag gaacttttta
    46201 tagataatcc tcgaaaaatt gtaatggatc aactaattta ggagaaatga tgaaagaaca
    46261 aaacacgata gaaatcgatg tatttcaatt acttaaaacc ttgtggaaac acaagctaat
    46321 aattttatta gtggcacttg tgacaggggc gggagctttt gcatatagca cttttattgt
    46381 taagccagaa tatacaagca ccacgcgtat ttacgtagtc aaccgtaatc aaggagataa
    46441 gccgggactg acgaatcagg acttgcaggc aggaacttat ctggtaaaag actaccgcga
    46501 aattatcctt tcgcaagatg tattggaaaa ggtagcgaca aatttgaaat tggatattcc
    46561 agcaaaaacg ttaactagca aagtgcaagt gactgtacca gccgacactc gtatcgtctc
    46621 aatctctgtc aaggataaac aaccagagga agccagtcgc attgctaatt ctctacgaga
    46681 agttgctgca gaaaagatca tcgctgtaac gcgagtatct gatgtaacga cgcttgaaga
    46741 agcgcgacca gctatgactc cctcttctcc aaatgttcga cgcaacacct tagttggttt
    46801 tcttggagga gccgccgtaa cagtaattac tgttcttttg attgagttgc tcgatacccg
    46861 tgtaaaacgt cctgaagatg ttgaagatgt actgcaaatg ccacttctag gagtcgttcc
    46921 agattttgat aaaatgaaat aggaggaagt tatgccaacg ttagaaatct cacaggcgaa
    46981 attagaactt gtgaaaaagg cagaggaata ttataatgct ttgtgcacga acctacagtt
    47041 aagtggagat gatttgaaag tattttctat cacttctgtg aaagcaggag aaggaaaaac
    47101 aacgacttcc accaatatcg cttgggcttt tgcgcgtgca ggttacaaaa cgcttctgat
    47161 tgatgcagac atgcgtaact ccgttatgtc aggtgtcttt aaatcaaggg aaaggattac
    47221 tggactaaca gaatttctat cagggacaac agacctgtca caggggcttt gcgataccaa
    47281 tattgagaat ctctttgtga ttcaggctgg ctctgtgtca ccaaatccga cagcccttct
    47341 tcaaagtaag aatttcagta caatgcttga aaccttgcgt aaatattttg actatatcgt
    47401 cgtagacact gcccctgtcg gtgtcgtgat tgatgcggct atcattatgc agaaatgtga
    47461 tgcttctatt ttagtgacga aggcaggtga aacaaaacga cgggatcttc aaaaagcgaa
    47521 agaacagttg gaacaaactg ggaagtcgtg tttaggagtt gtgttgaata aactcgatac
    47581 ttcagtagag aaatacggtt cttatgggag ttatgggaat tacaggaaac agaaaaaata
    47641 ggttgaggga tagaaatgag tgaaaaacta gcaaagcctt cagtagccat agtccagagt
    47701 tttcttgtta ttttattgac ttatctactt agcgctgtga gagaaacaga gattgtttca
    47761 acaacagcta ttgtacttta tatcctccac tattttgtct tttatatcag tgattatgga
    47821 cggaatttct ttaaaagggg atatttgatt gaacttgtcc agacattgaa atatatccta
    47881 ttctttgcgc tagcgattag tatttctaat tttttcttag aagatcgatt tagtatttcc
    47941 agaagaggca tgatttactt cctcttatta catgttttct tagtctatgt gctaaaccca
    48001 tttatcaagt ggtattggaa gcgggcttat cccaacttta aaggaagtaa gaagattctc
    48061 ctacttacag caacttctcg tgttgaaaag gtactggata gactaataga atcagatgat
    48121 gttgttgggg agttggtagc cgtcagtgtt ttagataaac cagattttca gcatgatgat
    48181 ttaaaggttg tagcagaggg ggagatagta aattttgcga ctcatgaggt ggtcgatgaa
    48241 gtctttatca atcttccaag tgaaaaatac aatattggag agcttgtctc tcagtttgaa
    48301 acgatgggaa ttgatgtaac agtcaatcta aatgctttcg attgggcacg taacaagcaa
    48361 atttgtgaga tggcaggact aaatgttgtg actttttcta caacatttta taagactagc
    48421 catgtgattg ctaagcgggt tattgatatt gtcggttccc tggtaggttt gatattatgt
    48481 ggtctagtca gtattgtgct ggttcctttg attcgaaagg atgggggttc tgcttttttt
    48541 gctcagacgc gtataggaaa aaatggccgc cattttactt tttataagtt tcgctctatg
    48601 tgtgtggatg ctgaggagaa aaaaagagaa ctcatggaac aaaataccat gcagggtgga
    48661 atgtttaagg tggacgatga tcctcgtatc acgaaaattg gtcattttat acggaagacg
    48721 agcttggacg agctaccaca gttttataat gttctaaagg gagatatgag tttggtaggt
    48781 acacgaccac caacagtgga cgagtatgag cactataccc cagaacaaaa acgtcgccta
    48841 agttttaaac ctggcataac aggtttatgg caggtcagcg gacgaagtga aatcaaaaat
    48901 ttcgatgaag ttgtcaaatt agatgtggcc tatattgatg gttggacaat ctggaaagat
    48961 attgaaattt tattgaagac agttaaggtt gtattgatga aggatggagc gaaatagttc
    49021 atatgaatga gagaattcaa atattaggaa ttactataga tccattaacg atgaaagaaa
    49081 cagtggatgc tgttgaacag tatgttttaa agaagcaccc tttgcacttg atgggagtta
    49141 acgcggataa aattaatcag tgctatgaag atgagaaaat caaaaaaatc gttaatgaat
    49201 caggaataat taatgccgac ggtgcttcag tagttttagc gagtaagttt ttaggaacac
    49261 cagttcctga gcgagttgct ggaatagact tgatgaaaca tttactagag ttgtctaatg
    49321 aaaaaggata ctcggtctac ttttttggag caaaagaaga cgttttacaa gatatgttaa
    49381 aaatttttga agaaagatat ccagctctaa atgttgttgg ctatagaaat ggatattttt
    49441 cgcctgaaga tgaaaaacat attcaggaag atattaaaga gaaaaaacca gattttgtgt
    49501 ttgtaggaat tacttctcct aagaaagaat atattatcca atcattcatg gataatggaa
    49561 ttaatgctgt gtttatgggg gttggtggaa gttttgatgt actatcaggg catatcaaac
    49621 gagctccatt atggatgcaa aatgctcacc tagagtggtt gtttcgtgtg gcaaatgagc
    49681 ctaaacgtct ctttaagcgt tattttgtag ggaatgtttc atttataaga aaagttttaa
    49741 gagcgaaaag gggatataaa ctttgaacca aacagaaata gttaaattga ttcagaaagt
    49801 tgaattggat gctataaaag agtttcaaaa aatttgtaaa gagaacaata tagatttctt
    49861 ccttcgtggg gggagtgtac ttggggcagt caaatatgat ggctttattc catgggatga
    49921 tgacatggat attgctgtgc ctcgtgaagg ctacgataaa cttccaggta tctttaagga
    49981 tagaattatc gcaggcaaat atcaggttct tgcttatcaa tattgcgata ctttacattg
    50041 ctactttcct cgcttattcc ttttagaaga tgaaagaaaa cgtttgggat tgccacgaaa
    50101 taccaattta ggtttgcatt tgattgatat cattcctttg gatggtgccc caaatcattc
    50161 atttttaaga aagctttact tcggtaaagt atactggtat cgttttttag caagtttagg
    50221 aactacctat gttggagacc atgtggatat gcattccgct aagcaaaaac taatcattgg
    50281 tttctttaaa aagctaggat ttgcaaaact attccctcaa aattatgtgt acagacgctt
    50341 ggataatctc tataaaaagt atgattggaa aaagcagaag tatgctggga caattaatgc
    50401 atctctgttt gccaaagaag tcatgccagt agagatttgg ggagaaggag tagagaagcc
    50461 ttttgaggat gccttcttta aagttcccac ggagtatgac cgctatctga aaagacttta
    50521 cggagaaaac tatcttcacg aagagcctag tgatgatgaa aagaaatcgc atttaggagg
    50581 acaataattt gttttgttat attattttgc attacaaagt cttagaggaa actatttctt
    50641 gtgttaaatc aataaaagaa ggcaattcca atacaaagca gatcgttatt attgataatt
    50701 tttctaataa cggtacgggt gaaaaactac aagagctgta tgagtcagat tcagagattg
    50761 atgtcttgat taaccatgaa aatgctggtt tcgctcgagg taataatgta gcatatcagt
    50821 ttgctaagga aaagtacaaa cctgatttta tggttatcat gaataatgat attgagatag
    50881 aaacagaaga gtttgaaaaa atcgtgacag atatctatcg gaaggaaaaa ttccatttgt
    50941 taggaccaga tatcttttcg acgacgtatc agcttcacca aaacccaaaa cggttgacgc
    51001 attatactta tgaagaggtt aaggctctca atgaaaaatt taagaaaggg agccaagtta
    51061 gtctagcatt aaaaattaaa tgttggttga agtctagtaa agttcttcgg acagcaatct
    51121 atcaaaatag gcgtaaaaag aaatcagtag actatagaaa acaggtagaa aacccaattc
    51181 ttcatggttc gtttattgta tattctagag attttattga gaaagaggag tatgctttta
    51241 atcccaatac cttcttctat tatgaaacag agatattaga ttatgaagct gagttaaaag
    51301 gatataagag aatttataca ccgaagatta aggtcttgca ccatcaaaat gttgcaacca
    51361 atcaagtcta tacaaactta gtagaaaaaa ccttgttttc aaacaaatgc aactttgaat
    51421 ccactagtta ttttttgaag ttgatgaaag aaaacgaggg tgtgtaaatg acttatttat
    51481 ttttactctg cctgacctta ttcttattaa ctttcttcta tttttttgct ttcaatcaag
    51541 atttgatagc tccgccagtt gtcatgtctg ttatgtttct cattagttct gtatttgccc
    51601 ttattaatgt gcaaaactgg aatattgagt atagtggttt agcttatctt ttgattatta
    51661 gtggcattat tgttttttca atgcctctct tggctcttaa ttcgcctatt ctaaatacca
    51721 agattaaagt gacggatcgg ctcattgata tccaattctg gaaaatagct cttactatta
    51781 tagttgacct cattattcta tatctttata ggagagagat tcataatctt gcacttagcc
    51841 atggttatac gggttcaaat tttcagtggt tctttagaaa tgctaccagt tatgaaggtg
    51901 agctaacagt gcgaacttcg attcgggtcc tcattcgtat cattgacgta tctgcttata
    51961 tttttggata tacttttatt aataatttct tcatttatag tcataaacgc tctaaagatt
    52021 tactgctctt agttccattc ttgattttta tttctaaaac cttattatct gggggtagat
    52081 tggatattat aaaaatttta attgcgtatg ttgtaatggc ctatattcag caaaaacgaa
    52141 aagttggctg ggataaggtc atctcccata aatatatgag acttggtttt gtaggcttga
    52201 tagctgggat tcctaccttt tactattctt tattcttatc tggacgttct acgactagaa
    52261 ctgtatttga aagtatttca acctatttag gaggttcgat tcagcatttt aatcagtata
    52321 ttcaaaatcc tattggagta gctgaggttt ttggcgatga gtcatttgta gctattatga
    52381 atattttggg taatcttggc tttgtcaatt acaatagtac cgttcactta gaatttcggc
    52441 agttagggat tactatgggt aacgtttata ctttctttag aagaccctgg catgactttg
    52501 ggttagtcgg tatgtatatc ttttcctttg ttgtcggtgt gttttttgct attttttatt
    52561 tgaaattaag aaagagccgt gctggtttta aattggatat tcatacaatt atttactctt
    52621 atttctttta ttggattttt ttatcgtcca ttgagcaata ctcgtttaca acaatcagtt
    52681 tgtttacact tgtatttata gtcttggttt acctaatggc tttcttctat tggaatttgg
    52741 atttccacag aggaaaacta gtaattaaac tctctgacac aagtattaaa tcggaaaact
    52801 gaaaacaata aaaatagaga ggatagttga tgaatagcaa aattaaaaat atactaacta
    52861 atttctctta tgtcatttct tcaaatcttt tgacagtctt gacctcttcc ttggttgtct
    52921 taattttccc caaattaatg ggggtaacag agtacagtta ctggcaactt tatatttttt
    52981 atctgaccta tatcggtttt ttccacttgg gttggattga tgggatttat cttaaatatg
    53041 gtggcttaga atataataat ttagatagaa aacagtttta ttctcagatg attctatttt
    53101 ctagcttctt aatgattatc tccttgctat tgtttggttt aaatgtatta gctgtaacag
    53161 attcgaatgc acgatatatt tataatatga ctattataag tatgataatc acaaatttaa
    53221 gaacgctcta cgtgtatgtt ttgcagatga caaaccgctt gaaggatagt tccatcattc
    53281 tactcagtga tcgcgtttta tatgtgctcc ttttattcct gtttattgta tttggttggc
    53341 atgaatacaa ggttatgatt ttggcagata ttctaggtcg atcattttct ctcatacttt
    53401 ccttctggat ttgtaaagat attgtgtttc agcctttgtc aaaattcatc tttaatataa
    53461 aagagtcttt tgataatatc cgagttggta tcaatttaat gttatccaac atcgcaagta
    53521 gtttgattat cggtattgtt cgtctaggaa tccaatggaa ctggaatatc gaaacattcg
    53581 ggaaagtatc tctgaccttg agtgtttcca atctattgat gactttcatt aatgccattg
    53641 gactagtcgt ctttccgcta ttaagacgaa caaaagcaga aaacttacct aagatttatt
    53701 ctaatttaag aaacgttttg atgcttatca tgttcgcgat tttgctcatt tactatcctt
    53761 taaaaattgt attagacctc tggttgccag cctatcaaga tgccttgatt ttcatgaccc
    53821 ttattttccc tatgtcagtc tatgaaggga aaatggcatt ggtcattaat acttacttaa
    53881 aggcattaag aatggaaaga gatatcctta gagtcaatgc cttagtaatg ttgatcagta
    53941 tgggagtgac cctggttaca acatacctgt taaatagttt ggagctgact gttgtatcga
    54001 tagttgtttt gctagctttg agaagtatca tagccgaatt aattctgtct aaaaaactgg
    54061 atgtttcggt taagaaggat attgtattag aatttctttt gacgcttgtc tttatttctt
    54121 caagttggta tttgccgatt gggctggcag taattgtcta cacaatagcc tacggtttat
    54181 atctctattt gaaacacgaa gatatcaaaa cctatttagc ttactttaaa gctagtaaaa
    54241 aaacatcaaa ttaaaaaatt atataatgat taagtggtag attctatttc taccgtttta
    54301 gatattcggg aggtaatgat gaaaaaaatt atgttagtat tcggtacacg tccggaagcc
    54361 atcaaaatgt gtccattagt caatgagttg aaaaaacacg aagatatgga aacaattgtg
    54421 tgtgttactg gacaacacaa agagatggtt agtcctgttt tagatttatt tggtgttgta
    54481 ccagattatg atttagaaat tatgaaggct aaccaaacct tgttctctat cacaactagt
    54541 atcttggaaa agataaaacc agttttagag aaggaacaac cagatattgt cctagttcac
    54601 ggtgacacta cgacaactta tgcagcagcc ttggcagcat tctatttggg aattaaagta
    54661 ggacatgttg aagctggttt gcgaacgtac aatttacaaa gtccatttcc tgaagaattt
    54721 aacaggcaat cgacatcaat cattgcaact taccattttg ctccaactga gttggctaaa
    54781 gaaaatctct taaaagaagg tagagagaat gtttatgtga ctggaaatac tgtcattgat
    54841 gctcttacaa ctactgttca agaggattat acacacactc atttagattt aaacgctaac
    54901 aatcgtctca tcttattgac tgctcataga cgcgaaaatc tcggcgaacc gatgagacat
    54961 atgtttagag cagttaaacg agtattgaat gaatacgaag atgttaaagt catttatcca
    55021 attcataaga atcctttggt acgtgaaaca gctgcagaga tctttggaga tacagaacgg
    55081 attcaaatta ttgaaccttt ggatgttctt gatttccaca acttcatgaa ccaaagttat
    55141 atgattttaa cagattctgg cggagttcag gaagaagcac cttctttagg aaaacctgta
    55201 ttggttatgc gcgatactac tgaaagacct gaaggagtag cggcaggaac cttgaaatta
    55261 gtaggaactg acgaagaaac aatttatcaa aacttcaaac tacttctaga tgattctgga
    55321 gaatacaaaa aaatgagtca ggctagcaat ccatacggta atggtgatgc tagtcaacag
    55381 attgttcaga ttttgcgtgg gatttaagaa gattctctaa aagagtctaa gaggaatcca
    55441 ctccacaaac ataaaactct tatgctatca tttatgattg agatagactc ataacttaat
    55501 atttttatcc taagaaaatt cgttcatatt caatatgaat gaaaaacaac gaagaaaggt
    55561 tatttcatta tgaaaggtat tattcttgca ggcggctcag gtacccgcct gtacccactt
    55621 actcgggctg cgtcaaaaca gctgatgccg gtttatgata aacctatgat ttattatccg
    55681 ttgtcgacat taatgttggc tggaattaaa gatattttga ttatctcaac tcctcaagat
    55741 ttgccccgtt ttaaggactt gctcttggat ggttccgaat ttgggatcaa gctttcctat
    55801 gcggaacaac ctagtcccga tggacttgct caggcttttc ttatcggtga agaatttatc
    55861 ggtgacgata gcgttgcctt gattttaggc gacaatatct accatggtcc tggtctgagc
    55921 acaatgcttc aaaaagcagc caagaaagag aaaggtgcga ctgtttttgg ctaccaagtg
    55981 aaggatccag agcgttttgg tgtggttgag tttgatacag acatgaatgc tatttctata
    56041 gaagaaaaac cggagtatcc tcgctccaac tatgcagtga caggactgta tttctatgat
    56101 aatgatgttg tggagattgc taaacagatc aaacctagtg ctcgtggcga gttagaaatt
    56161 acagacgtta acaaggctta cctaaatcgt ggtgaccttt ctgttgagct gatggggcgt
    56221 ggttttgcct ggttggatac gggaacccat gaaagcttgc tagaagcttc tcagtatatt
    56281 gaaacggttc agcgtatgca gaacgttcaa gtggcaaatc tagaagaaat ttcctatcgt
    56341 atgggctaca ttagtcgtga agacgtgctg gaattggctc agcctcttaa gaaaaatgaa
    56401 tacggacaat atttgctccg tttgattgga gaagcataga tgtcagataa tttttttgga
    56461 aagacacttg tggtacgcaa gattgatgct ataccaggac tgctagagtt tgacattccc
    56521 gttcatggag acaatcgtgg ttggtttaag gaaaatttcc agaaggaaaa gatgctaccg
    56581 cttggttttc ctgaaagctt ctttgctgca gggaaactgc aaaataacgt cagcttttct
    56641 cgcaaaaatg ttcttcgagg actccatgct gaaccttggg acaagtatat ctctgttgca
    56701 gacgatggga aggttttagg atcttgggta gatttgcgtg aaggcgagac ctttggaaat
    56761 gtttaccaga cagagattga tgctagcaag ggaatttttg tccctcgtgg cgtagccaac
    56821 ggttttcaag tcctctcaga tacagtttcc tatagctatc tggtcaatga ctactgggct
    56881 cttgaactca aacccaaata tgcctttgtt aactatgctg acccagcatt gggaattgag
    56941 tgggaaaacc tagcggaagc tgaggtttca gaggcagaca aacaccatcc tctattaagg
    57001 gatgtcaaac cacttacgaa agacgagttg taaaaggaaa cattatgact gaatacaaaa
    57061 aaattatcgt gacaggtgga gctggtttta tcggttctaa ctttgtccac tatgtttaca
    57121 ataactttcc agatgtccat gtgacagtgc tggacaagct gacttatgca ggtaatcgtg
    57181 ccaatatcga ggaaatttta ggcgaccgtg ttgagttggt tgttggagat attgctgatg
    57241 cagccttggt agacaagttg gcggctgaag cggatgctat cgttcactat gcggcagaaa
    57301 gccacaatga taactcgctc aatgacccga gtccatttat ccacaccaac tttatcggaa
    57361 cttacacact tttagaagcg gctcgtaaat acgacattcg tttccaccat gtatcgactg
    57421 atgaagtcta tggtgacctg cctctgcgtg aagatttgcc aggtcatggg gaaggcctag
    57481 gtgagaaatt taccgctgaa accaagtaca atccaagctc gccttactca tcaaccaagg
    57541 ctgcttcaga cttgatcgtt aaagcttggg tgcgctcatt tggtgttaaa gcaacgattt
    57601 ctaactgttc aaacaactat ggtccatacc agcatatcga gaagttcatt ccgcgccaga
    57661 ttacgaatat cttgagcggt atcaagccaa aactctacgg agaaggtaag aatgtgcgtg
    57721 actggattca caccaatgac cattcatcag gcgtttggac gattctgacc aagggtcaaa
    57781 tcggtgaaac ttacttgatc ggtgctgacg gtgagaagaa caacaaggaa gtgttagagc
    57841 tcattctcaa ggagatgggg caacccgctg acgcttatga ccatgtgacc gatcgagctg
    57901 gtcacgactt gcgttatgcg attgatgcta gcaagctccg tgatgagttg gggtggaagc
    57961 cagagtttac caactttgaa gcaggcctca aagagaccat caagtggtac acagataacc
    58021 aagactggtg gaaatctgaa aaagaagcag tagaggctaa ctatgctaaa acgcaacaag
    58081 tgattaaata ataagatact aaaaaagcaa gagacctcga ggtctcttgc ttttctagta
    58141 tgtagtaagc ttttattttc ttacttcttg tttataaaac tctttaaggg catcttgcca
    58201 ggttgggatg acgaaacctg ttgcctttgc ctttgccaaa ctcatagttg agttgagagg
    58261 tcgtttagcc ttagcgggga acttgctaga gtctactggc actacttcaa catcactgtc
    58321 cttaagaatc tcgctagcaa agtcatacca agtggtgtct tcagctgcgt catttgataa
    58381 gtgatagtag ccatactctt tttgattttc agtcacatag gtcatgaatt cggccaaggt
    58441 ccgtgtccaa gttgggcgac cgtattggtc gttgaccact gtgagcgttt tatgggtttt
    58501 ggctaggctt tgcatggtaa agacaaagtt ttttccataa tttccaaaaa cccaagcagt
    58561 acgaatgatg taatgctgtg acgtaaggtt ttcaacaagt tcttctccca ttcgcttggt
    58621 acgtccgtac tctgtttgcg gatcaggtat gtcatcgact tcccactctt gtcctactgg
    58681 tttctttcca tcaaagacgt agtctgttga gatatagacc agaatagctc cgtatttctc
    58741 agaggccttg gctacatttt cagttccagt tacgttgatg gcaaaatcca gttctttccc
    58801 ttcatcttcg gctgcatcaa cagcagtgta ggctgcacaa tgatagacta gagttggctt
    58861 aacctcagca aagacttttt caaccatttc agaattagtg atatccattt cggtcacatc
    58921 cactgcaaca tagtccacat ttcgctcatc tagtaaataa cgtagttcgg taccaagttg
    58981 accatttgca cctgtaatta agatcatatt tttctccttg atagttctta tacttaatta
    59041 tatcaaaaat atagaaaaat cggtttttag tgaacccttt tttggtataa actttgttag
    59101 tgaagcgcaa gagagccgaa tagttattac tttagaatat ccttaaaagt atttttcaga
    59161 atttaccaaa ttaattaaaa aattcagaaa attatattga catctctctg aaaagagtct
    59221 ataatagaga gaaagtttta aaggagaaga tgatgaaaag ttcaaaacta tttgcccttg
    59281 cgggtgtaac cttattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca
    59341 ctaaagctga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
    59401 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
    59461 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
    59521 atggattgac ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg
    59581 aagaatacgc ggtagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
    59641 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa
    59701 aagggggaat cacagatttc tcacaagtag gaattaaggc tctggatgat cagacagttc
    59761 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg
    59821 cgccagttaa tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc
    59881 caagtagtct cttgtataac ggtccttatt tgttgaaatc cattgtgact aaatcttctg
    59941 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatgtt gacaaagtta
    60001 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
    60061 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
    60121 tgaaggacaa tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata
    60181 ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag gcatcgacta
    60241 aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggtttt gatcgtacag
    60301 cctatgcctc tcagttaaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
    60361 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
    60421 tggtcactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
    60481 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
    60541 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
    60601 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
    60661 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
    60721 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
    60781 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
    60841 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
    60901 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
    60961 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
    61021 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
    61081 aaggcacaag tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg
    61141 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
    61201 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
    61261 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
    61321 ctgcccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
    61381 cttgtttcct attgctttct cagctattat ttgttatatt aaaagtataa ttatttttta
    61441 tttatcaggg ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta
    61501 aacgcttgct aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac
    61561 gttgtaaata tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg
    61621 cattctttgg gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact
    61681 taccagctga tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg
    61741 aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag
    61801 aagaagaact attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata
    61861 aacctgcagc tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag
    61921 agaaaaaaga acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc
    61981 aactatcctc aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg
    62041 gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg
    62101 aaaagggcaa atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt
    62161 ttgtcggtta tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt
    62221 ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca
    62281 ctctcaagtc agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag
    62341 tgactctacc agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg
    62401 cgggctctta tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg
    62461 taaaagcgga tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg
    62521 tgacttatga tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc
    62581 gtgtcaagga atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc
    62641 aagtctttat caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga
    62701 caacagcaga gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga
    62761 cagtacgcct gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc
    62821 acaatcaagt cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta
    62881 gtttcctcgg caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg
    62941 gggcaaccat gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc
    63001 caatgaaaga cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg
    63061 ctggtgtttg gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt
    63121 tgacagctta taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat
    63181 ggcaatggga aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa
    63241 gggctaaggt tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg
    63301 gtgccattgc ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata
    63361 tcacagctta ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga
    63421 ccttggatgg tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc
    63481 ttaaaggata tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta
    63541 agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga gaaggctaag aaatatggag
    63601 ctcatctagg tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg
    63661 aaaaaattct ccgtaagaat ccagatggaa gttatagcta tggttggaac tggctagatc
    63721 aaggtatcaa cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag
    63781 atttgaagaa aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg
    63841 gtcaatcagg tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac
    63901 aaggctggcg ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc
    63961 actgggcagc tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca
    64021 ctcgctttat ccgtaaccac caaaaagatg cttgggttgg ggactacaga agttatggtg
    64081 gtgcagccaa ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag
    64141 gaagaagtga ctacaatggc tacgtgacta acctctttgc tcatgacgtc atgactaagt
    64201 acttccaaca cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata
    64261 acggtagcac ctataaatgg actccagaaa tgcgagtgga attggtagat actgacaata
    64321 ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta
    64381 cagtaacgct caacggacgt gtgatccaag atggttcagc ttacttgact ccttggaact
    64441 gggatgcaaa tggtaagaaa ctttctactg ataaggaaaa gatgtactac ttcaatacgc
    64501 aggccggtgc aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt
    64561 acaagctaac tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa
    64621 ttaccctaga tcttctagca aatcaaccat acgttctcta tcgttcaaaa caaaccaatc
    64681 ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca aggatttaac agtggtacct
    64741 tgaaacattg gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg
    64801 caaacgatat gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa
    64861 ctggcttgaa accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg
    64921 ccaaggcaag tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt
    64981 ctctcgccct caactatgta aaagcctacg cccacaatac acgtcgtgac aatgctacag
    65041 ttgacgatac aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct
    65101 caaatgttac tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa
    65161 ttcgtacctt tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca
    65221 ccttcaagca agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg
    65281 ttgaaggtgt tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac
    65341 gtggttggaa tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa
    65401 atggactagt gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg
    65461 aagcaggtaa gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg
    65521 cttttgtagt cggtaaggga gaattccagt caggtcgtcg tggcactcaa gcaagcaact
    65581 tggaaatgca tgaattgcca aatacttgga cagattctaa gaaagccaag aaggcaacat
    65641 tccttgtgac aggtgcagaa acaggggata cttgggtagg tatctactca actggaaatg
    65701 caagtaatac tcgtggtgat tctggtggaa atgccaactt ccgtggttat aacgacttca
    65761 tgatggataa tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg
    65821 ctctgaagaa ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg
    65881 ctttgaaaga ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag
    65941 cgcgtgcaga gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg
    66001 ctttggtagc agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg
    66061 caaatgcctt tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg
    66121 taggcaagcc tgcaaccatg gtcttgaaag aaccaactga aatcactgga cttcgttatg
    66181 ttccacgtgg atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg
    66241 agtctggcaa ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag
    66301 acattgattt tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt
    66361 acggagatgg tggcgataaa taccaatctg cagcggaact catctttact cgtccacagg
    66421 tagcagaaac acctcttgac ttgtcaggct atgaagcggc tttggctaag gctcagaaat
    66481 taacagacaa agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga
    66541 cggataacca tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat
    66601 taaaagattc tgctacgaaa ccagatgctt caactgtaga gaaacctgag tttaaactta
    66661 gctcacttgc ttcagatgaa gataaggcac cggcaccgga actaaaacaa gaagtgacga
    66721 agcgagaaac agctgaacaa agcttgccag caacaggtga gagtcaatct gacacagccc
    66781 tcttcctagc aggagttagc ctagccctat ctgctctctt tgtagcaaaa acaaagaaag
    66841 actagtattt agtaaaacct cttaacaaga ttacgaaatc cgtttcctat ctttcccaat
    66901 gaggtttaaa gtacagaaaa agcctgagaa gacatcttct caggcttttg ttaagcatat
    66961 aaatgcaata gtgctatgaa aaaatcaccc agaaaaatct gggtgataaa tgttatggtt
    67021 gtgctggttg aggattctga ttttggttct ggttttgttg accaggcgtt gtatttggtt
    67081 gctggttatt ggtattattg tttgcactat tattcgtgct tggagtagtt gagcttgact
    67141 gtgaagttga actttctgat gtcgagctcg aactttctgg tgttggggcc tgttgcggag
    67201 caggagcagt ccatgcagaa cgagcacctt ttttaaagac gaactcacca cttcgataga
    67261 gaccttctgg catagtccag tcgccagggt tgttatcctc agacagataa gtcatcattg
    67321 aacggtaaac cttagctgca acatagaagc catcaccaac gataggagtc aggcggtttg
    67381 agtaacctgt ccataccgcc attgaatatt tgcgagtata accaacaaac atttcgtctg
    67441 gagctacata accagtattt ttgatgtagt tttcaatttc atcatctgta tagtttgatg
    67501 taccagtctt accagcttga ggtagccaag ggagataagc accacgaccc gttccgtatg
    67561 ccaagacagt cttcatcatt tctgtcatca tataggcggt cgtctctttc atggcacgag
    67621 taccaggatc agcgtattct tttgagctac catcgctaaa gacgattttg ttgatataca
    67681 ttggtttatg gtagatacca ccgttagcaa aagcagcgta agcagcagcc attttctcac
    67741 tacttgctcc gtactttttg tttgactcag tcgtattact tgaaatggcg tttgcataat
    67801 gcatgcttgg atagtcgata ccaagaccat taagaaaggt tttagctcta tctagaccga
    67861 ccttattcaa agtctcaacg gctgtgacat tacgtgactg ttgaagtgca tactggattg
    67921 taatatttcc aaagtagact ttatcccagt tgtagagggg agtatcagta cctggatagt
    67981 tataaggaac atcatgtaca atcgaagcag ttgagtcgta gatgtcatac tctaaggcag
    68041 gagcatagtc tgtgattggc ttcatggcag aaccccagtc acggttggtt tcaacagctt
    68101 ggttgattcc gaaggaaaca ttgcttgatt ggtgacgaga acctaactga gcaataactt
    68161 tcccgttaga aacatcaaca atggtagaag cgacttgcaa ttcatcgtct ggataggcaa
    68221 cgtattcgtc tgtattgtaa atatcccaca gatgtttttg agcttcttgg tctacatttg
    68281 tgtagacatc catcccagtt gtgagcaggt tatagcctgt ttcttcttca acttgattga
    68341 tgacttcctt gaggtaatta tccatgtaag cagggtaatt acttgctgat ttgagacttt
    68401 gtagtccatc agtaattggt gtattgactg ctttctcata ctgttcagca gagatgtagc
    68461 cttgattttt catttcagat aagaccaagt ttcggcggtc ttgggctgct tctggatgtg
    68521 aataggggtc atattggttt ggtgcctgag gcattccagc cagcaaggct aactgaggta
    68581 aacttaaatt attgaggtct ttaccatagt agttttgagc tgctgtctgc attccatagt
    68641 tcccattaga catgtagacc ttatttatat agtaggtcaa gatttcttgc ttggttgctt
    68701 tttgttctaa ctgaatcgct aaccaagctt cctgagcctt acgagaaata gtctggtcgg
    68761 aagtcgaagt tgaaaagtaa gtcaacttaa tcaactgttg agtgagagtt gatccacctt
    68821 ggagggaatt gctttgcaga ttgcgcaaga aagctcccag gatacggatg gtatcaatcc
    68881 ccctgtggtc gaagaagcga tggtcttcga tagaaacgat tgccttaacc aaatctgtgg
    68941 gaatatcatt agcttgggca ttgacgcggc gttcagaacc caagtcagca atgagttgat
    69001 ttttattgtc gtagatttta ctagaagttg ttgcaactag tttactctcg gataggctag
    69061 gagccttgct aacatagtag aaaaaaactc ctccgcctaa gacaatggct gcgataacca
    69121 agcttaagaa gctaatgctc agatacttga ttaggcgcag aatcgttggt ttgttcatct
    69181 tgttttacca cctaataaat gttctttgat aacattgaga taaggaattt gagggaaggc
    69241 accagccttg atttcatatc catattctcg aatatattca agtggcattg atttttgtcc
    69301 cttatcttga tgatagaagc gaatcaaatc gaatgccggc aataagtagg tttcttgctg
    69361 agaagaaaag tgaagaagga caaagcagat tccttgttgg gcaaggactt gttccatatg
    69421 ctgaatctga tgtggatgaa aatttttcat cggaatcgca cgtttttgtt ttgtttcctt
    69481 gacttcaaag tcgatgtaat atccattata aacgccagaa tagtccgtcg ttgaagcttg
    69541 tcgaaaatag gcttcaacaa tcttggcacg acttcgttgt ggatagtcca cttgtacgat
    69601 ttgaatagga gttggtttct tatgtataac agccaagcct tgagacaaat agtagtcgtt
    69661 ggtagcattg atcatctttt caaaagacat tcctcgattt gcgaaatttt tgggttgaga
    69721 aagagatgtt tgtctttttt gtgatgaaac tttatgtgga tagttgacca taattctcct
    69781 tattggtaca ataacatcac tttattatac cataatttgc acagaaaggg ttaaaaatgg
    69841 ctacagcttt ggttttaggc tattctgctt ttgatttggg tttattttct gataaggatc
    69901 ctcgtcttaa attgattaaa aaagcgatac gtaaagattt agaggctatg gcagcagatg
    69961 gggtgtcttg gcttgtgttt acagggagtt tggggtttga atattgggtt ttagaggttg
    70021 ctcaggagat gaaaaccgaa tacggtttcc agttggccac catttttgct tttgaaaccc
    70081 atggggaaaa ttggaatgaa ggcaatcaga tgaaactgag tcgctttaag caggtagact
    70141 ttgtcaaata tgcctatcct cgctatgaac acaaggggca gttaagagat taccagcagt
    70201 ttttgctgga aaacacgact agttcctatc ttttttatga tgaagaaaat gaaacaaaac
    70261 tagcttattt ttaccaaaag atgaaaaatc aagaggacta ttttataaag agattaacat
    70321 ttgatcaatt aaatgaactt gctgaaaatt tttccgaaaa ttgaagcttt gaccttgatt
    70381 tttgtttgcc tttttttata taataatact agcaagcgag aatggagaga gacatggcaa
    70441 gtattatttt ttcagcgaaa gatatttttg aacaagagtt tggacgtgaa gtccgtggct
    70501 ataataaagt agaagttgac gagtttttag acgatgtcat caaggactat gaaacctatg
    70561 ctgccttggt caagtcactt cgtcaggaaa ttgcggattt gaaggaagaa ttaactcgta
    70621 aaccgaaacc ttcaccagtt caagcagaac cccttgaagc ggcaattaca agttctatga
    70681 cgaattttga tattttgaaa cgcctgaata gattggaaaa agaagttttt ggtaaacaaa
    70741 ttttagataa ctcagatttt taagtagtta tttgagatgt gcaatttttg gataatcgcg
    70801 tgaggagaat tgcttctcat gaggaaagtc catgctagca caggctgtga tgcctgtagt
    70861 gtttgtgcta ggcgaaacca taagcctagg gacgagaaat cgttacggca gttgaaatgg
    70921 ctaagtcctt ggataggcca gagtaggctt gaaagtgcca cagtgacgga gtctttctgg
    70981 aaacagagag agtggaacgc ggtaaacccc tcaagctagc aacccaaatt ttggtcgggg
    71041 catggagtac gcggaaacga acgtagtatt ctgactgcta tcagctagag ctgttagtgg
    71101 tagacagatg attatcgaag gaagtggtcc tagtcacttc tggaacaaaa catggcttat
    71161 agaaaattgc atataggttg gggctgagaa attttctcaa cctcattttt taaagtggac
    71221 atatagaaag gtcttgcaag actgtaacat gaaaaaagaa tttaatttaa ttgcaactgt
    71281 ggcagcaggg cttgaggctg tcgttggtcg tgaagtgcga gagttgggct acgattgtca
    71341 gattgaaaat ggacgtgttc gttttcaagg agacgtgaga gctattatcg aaaccaacct
    71401 ttggctgcgg gcagcagatc gtatcaaaat tatcgtagga acgttccctg ctaagacttt
    71461 tgaagagcta tttcagggag ttttcgcttt agattgggaa aattatttac cacttggagc
    71521 tcggttcccg atttcaaaag ctaaatgtgt taagtccaaa cttcacaatg agcccagtgt
    71581 tcaggctatt tctaagaaag ctgttgtcaa gaaattgcag aaacactatg ctcgcccaga
    71641 aggggttcct ctgatggaga atggcccaga gtttaagatt gaggtctcta ttctcaaaga
    71701 tgtggcaact gtcatgattg atacgaccgg gtctagcctc tttaaacgtg gttatcgtac
    71761 cgaaaaaggt ggcgctccta tcaaggaaaa tatggcagca gccattttac aactttctaa
    71821 ctggtatcca gacaagcctt tgattgatcc gacctgtggt tcggggactt tctgtattga
    71881 ggcagttatg attgctagaa agatggcgcc aggtcttcgt cgctcttttg catttgagga
    71941 atggaactgg atcagcgatc gcttgattca agaagtgcgc acagaagcgg ctaaaaaagt
    72001 agaccgtgag cttgagctgg atatcatggg ctgtgatatt gatgctcgca tggtggaaat
    72061 tgctaaggcc aatgctcagg tagctggtgt tgcaggagac attactttta agcagatgcg
    72121 cgtgcaggat ttacgttccg ataaaatcaa tggagtaatc atttccaatc cgccttatgg
    72181 tgaacgtttg tcagatgatg caggggtgac caagctctat gctgagatgg ggcaagtatt
    72241 tgcaccgctg aaaacttgga gcaaatttat cctgactagt gatgaagctt ttgaaagcaa
    72301 gtatggtagc caagcagata agaagcgtaa gttatacaac ggaaccttga aagtggatct
    72361 atatcaatat tttggtcagc gtgtcaaacg gcaagaggta aaatagaaag gatactcatg
    72421 agtaaaaaaa gacgaaatcg tcaaaaaaaa gaaggtcaag aaccgcaatt tgattttgat
    72481 gaagcaaaag agctaacagt tggtcaagct attcgtaaaa atgaagaagt ggaagcagga
    72541 gtcttgcctg aggattccat tttggacaag tatgttaagc aacacagaga tgaaattgag
    72601 gcggataagt ttgcgactcg tcaatacaaa aaagaggagt tcgttgaaac tcagagtctg
    72661 gatgatttaa ttcaagagat gcgtgaggct gtagagaagt cagaagcttc ttcggaggaa
    72721 gttccatctt ctgaagacat cttactaccc ttgcctctgg acgatgagga gcaaggcttg
    72781 gatcctctat tgctagatga tgaaaatcca acagaaatga ctgaagaagt ggaagaggag
    72841 caaaaccttt ctcgtctgga tcaagaggac tcagaaaaga aaagtaaaaa aggctttatt
    72901 ttgaccgttt tggcgcttgt atcagtaatt atttgtgtca gtgcttatta tgtctaccgt
    72961 caagtggctc gttcgaccaa ggaaattgaa acttctcaat caactacagc caatcaatcg
    73021 gatgtggatg attttaatac actttatgac gccttttaca cagatagcaa taaaacggct
    73081 ttgaaaaata gccagtttga taaactgaat caactcaaga ctttacttga taagctggaa
    73141 ggtagtcgtg aacatacgct tgccaaatct aaatatgata gtctagcaac gcaaatcaag
    73201 gctattcaag atgtcaatgc acaatttgaa aaatcagcta ttgtggatgg tgtgttggat
    73261 accaatgcca aagccaaatc ggatgctaaa tttacagata ttaaaactgg aaatacggag
    73321 cttgataaag tgctagataa ggctatcagt cttggtaaga gccagcaaac aagtacttct
    73381 agctcaagtt taagtcaaac tagcagctca agttcaagtc aagcaagttc aaatacgact
    73441 agtgagccaa aaccaagtag ttcaaatgag actagaagta gtcgcagtga agtcaatatg
    73501 ggtctctcga gtgcaggggt tgctgttcaa agaagtgcca gtcgtgttgc ctataatcag
    73561 tctgctattg atgatagtaa taactctgcc tgggattttg cggatggtgt tttggaacaa
    73621 attctagcaa cttcacgttc acgtggctat atcactggag accaatatat ccttgaacgt
    73681 gtcaatatcg ttaacggcaa tggttattac aacctctata agccagatgg aacctatctc
    73741 tttaccctta actgtaagac aggctacttt gtcggaaatg gcgctggtca tgcggatgac
    73801 ttggactact aagcagtcgt tacaaaattc tttcttttca aaagtaaaaa tgataaaata
    73861 aaacaaatga aacaagagga gtgtcaaatg acaaaagcta actttggtgt cgtaggtatg
    73921 gccgtaatgg gtcgtaacct tgcccttaat attgaatcac gtggttacac agttgctatc
    73981 tacaaccgta gtaaagaaaa aacggaagat gtgattgctt gccatcctga aaagaatttt
    74041 gtaccaagct atgacgttga aagttttgta aactcaatcg aaaaacctcg tcgtatcatg
    74101 ctgatggttc aagctggacc tggtacagat gctactatcc aagcccttct tccacacctt
    74161 gacaaaggtg atatcttgat tgacggagga aacactttct acaaagatac catccgtcgt
    74221 aatgaagaat tggcaaactc aggtatcaac tttatcggta ctggagtttc tggtggtgaa
    74281 aaaggtgccc ttgaaggtcc ttctatcatg cctggtggac aaaaagaggc ctacgaattg
    74341 gtttcggatg ttcttgaaga aatctcagct aaagcaccag aagatggcaa gccatgtgtg
    74401 acttatatcg gtcctgatgg agctggtcac tatgtgaaaa tggttcacaa cggtatcgag
    74461 tacggtgata tgcaattgat cgcagaaagt tatgacttga tgcaacactt gctaggtctt
    74521 tctgcagagg atatggctga aatctttact gagtggaaca agggtgaatt ggatagctac
    74581 ttgatcgaaa tcacagctga tatcttgagc cgtaaagacg atgaaggcca agatggacca
    74641 atcgtagact acatccttga tgctgcaggt aacaagggaa ctggtaaatg gactagccaa
    74701 tcatctcttg accttggtgt accattgtca ctgattactg agtcagtgtt tgcacgctac
    74761 atttcaactt acaaagaaga acgtgtatat gctagcaagg tgcttccaaa accagctgcc
    74821 ttcaactttg aaggagacaa ggctgaattg attgaaaaga tccgtcaagc cctttacttc
    74881 tcaaaaatca tttcatacgc acaaggattt gctcaattgc gtgtagcctc taaagaaaac
    74941 aactggaact tgccatttgc agatatcgca tctatctggc gtgatggctg tatcatccgt
    75001 tctcgtttct tgcaaaagat tacagatgct tacaaccgcg atgcagatct tgccaacctt
    75061 cttttggacg agtacttctt ggatgttact gctaagtacc aacaagcagt acgtgatatc
    75121 gtagctcttg cggttcaagc aggtgtgcca gtgccaactt tctcagcagc tattacttac
    75181 tttgatagct accgttcagc tgaccttcca gctaacttga tccaagcaca acgtgactac
    75241 tttggtgctc acacttacca acgtaaagac aaagaaggaa ccttccacta ctcttggtat
    75301 gacgaaaaat aagtaggtca gccatgggga aacggatttt attacttgag aaagaacgaa
    75361 atctagctca ttttttaagt ttggaactcc agaaagagca gtatcgggtt gatctggtag
    75421 aggaggggca aaaagccctc tccatggctc ttcagacaga ctatgatttg attttattga
    75481 acgttaatct gggagatatg atggctcagg attttgcaga aaaattgagc cgaactaaac
    75541 ctgcctcagt catcatgatt ttagatcatt gggaagactt gcaagaagag ctggaagttg
    75601 ttcagcgttt tgcagtttca tacatctata agccagtcct tatcgaaaat ctggtagcgc
    75661 gtatttcggc gatcttccga ggtcgggact tcattgatca acactgcagt ctgatgaaag
    75721 ttccaaggac ctaccgcaat cttaggatag atgttgaaca tcacacggtt tatcgtggtg
    75781 aagagatgat tgctctgaca cgccgtgagt atgacctttt ggcgacactt atgggaagca
    75841 agaaagtatt gactcgtgag caattgttgg aaagtgtttg gaagtatgaa agtgcgaccg
    75901 agacaaatat cgtagatgtc tatatccgct atctacggag caagcttgat gttaaaggac
    75961 aaaaaagcta cattaaaact gtgcgtggtg ttggatatac catgcaagaa tagaaaagca
    76021 gttgcagttg tgtaactgct tttttgagga gtttttatat attgacatgc agtcgggtct
    76081 ttgctacaat cgttttagga ggatatatag atgaaacttt tgaaaaaaat gatgcaagtt
    76141 ctactagcag tctttttctt tggtttgcta gctacaaata cggtatttgc gaataccaca
    76201 ggtggccgat ttgttgataa ggataataga aaatattatg taaaagatga tcataaagca
    76261 atctattggc ataaaataga cggtaaaact tactattttg gtgatattgg agagatggtt
    76321 gtcggttggc aatacttaga aattcctgga acaggttatc gtgataattt attcgataac
    76381 caaccagtta atgaaattgg ccttcaggag aagtggtact attttggaca agatggtgct
    76441 ttgctagaac aaacagataa acaagtacta gaggcaaaaa cgtctgaaaa tacaggaaaa
    76501 gtatacggtg aacaatatcc tctatctgct gaaaagagaa cttattattt tgataataat
    76561 tatgctgtaa agacaggctg gatttatgaa gacggcaatt ggtattattt aaataagcta
    76621 ggaaattttg gcgatgattc ttacaatcca ctaccaattg gtgaagttgc taagggttgg
    76681 actcaagatt ttcatgttac tattgacatt gatagaagca aacctgctcc atggtactac
    76741 ctagatgctt caggtaagat gcttacagat tggcaaaaag taaacggaaa atggtattat
    76801 tttggctcct ctggttctat ggcaacaggt tggaaatatg tacgaggcaa atggtattac
    76861 ttagataata aaaatggtga tatgaaaaca ggatggcaat accttggtaa caagtggtac
    76921 tacctccgtt catcaggagc aatggcaact ggttggtatc aagatggttc aacttggtac
    76981 tacctaaatg caagtaatgg aggtatgaag acaggttggt tccaggtcaa tggcaaatgg
    77041 tattatgcct atggttcagg tgctttggca gtgaatacga ccgtagacgg ctattctgtc
    77101 aattataatg gcgactgggt tcggtaatga cagggtgctt ataattatat tagaacactc
    77161 gcttaatcaa agaagtgact ttgttgtact tgacctgacg attggggaga ttaaaaagca
    77221 tgtgaaatct acacatgctt ttttgttagt tatgagtgtt gaacttgact aaccattgac
    77281 aaaagataag agcaatcaaa ataagataca aaaatatcaa tgctaactgc accgaaacgc
    77341 ccgatgctat ggatagggct aatagggaga gcagggacgg ggcgagaatg tccactgtgc
    77401 tcagagcaga gcccaccgtc cccatcttgt cactggggat ataggcaaag acagctgctt
    77461 gtaggcgagg gctgagaatg cctataatcg tagaactgat gaaactggtc atgaaaatta
    77521 cgatataggc ttgataaagg atactagtta ttagagccaa tagggaaatc tcacagaaaa
    77581 ccaagaggtg cgtgaaacgg atatttttaa atagattact gctggtcata ttgccaagga
    77641 tagctccaca agacatgatg atggagagca gggcgaggag ttgcccaatg cttagttgtg
    77701 ctagtgtttg ttggatgaag cggagggcaa tcagccgagg ggacacatcc aagatggcaa
    77761 tcatactggt cgtcagaaac agtagtatga cggtatcttt taacctcagg agcacagcca
    77821 gcgattgttt aagatgttga aaatatttct taaaactcag tgctgtatgt gacatttcaa
    77881 tccttttttc aacctcatac aaggtatgtc taataacata caggcccaaa aaggcaatga
    77941 caaaagtcag agtgttgata agggaaatag tttgaatact tataacattg ataaggaatg
    78001 cgccagccag attggcgaca atgcggacaa ccctcatcag agactgccta aaccccatgg
    78061 catcatgcag gtcgtcctta attacactga tgtagagggc gttcatcatg taggcagaca
    78121 ggtagctcaa ggtgtcagag atgaggttga tgatgacaat cataatgact gaaactaatg
    78181 aaaagggcga caagacgaga aatactgtca aaatagcgta gagcaggatt ttgattttgg
    78241 caatccagag tgcgtgtttg actctatttt cttgaaaatc tcctagaatc ccgagaaaga
    78301 gttgcgatag taggggaacc atctctgaaa tggaaatcag taaaatcgct agcggagcga
    78361 aattgtactg agccacataa ttgataatgg cgaggtagaa aatactgtcg ccgaatgatg
    78421 aaaaacagct gtttagcagc aactgtctat atatgttgtt tgtccaaaat aatttcatac
    78481 ttttctcctt atgtctgcac atcgaatggg aatttattat ttaatagaca ccaatatacc
    78541 ccatgcttcc tattccgaag tcaaacaaat ctgctttacc actatctcct tgaaacatca
    78601 gtaaaccgtg atcatctcgt tcagaacatg ctaaaattac ctgttggatt tttttcatca
    78661 gtaatttgtt ttgattgtag acagtggttt gtagtaagct agttattccg tggcaatatc
    78721 ctgtcatcat ttttagatga tggttaaaaa caaattcttg atatttacta ataatatctt
    78781 tgtttccgtc acaatcgtac atacaaagat ataagattat tccggaaatt cctttgcacc
    78841 aagaaagttg taaatttcct aaattttcag tattagaagt aactttttct aataattttt
    78901 ttaattcagt atggaatata tggagatcat tatagaacat agaaggttct aagactttag
    78961 aataggcaaa taaagcatat gcaatttcac aatatccatg agcaaagcta tagtctaaaa
    79021 tgctttcttt ggctgtatct ctttgtagga aataatgata aatttcccca tatactattg
    79081 tggatgaaag ttttaagagt attgtcattg gtaaattgat agtattttat taatggtaat
    79141 aggacaccag attttcccaa tgcaaagtct atttcctcta gagtatcata attctctatt
    79201 aatttcttag cggtgacgtt tgctaattgt agatagtatt gatttttact gatagaaaat
    79261 aaatgtagga gtaaccatag atagcctgca tcaccaaata gcagtgagta ttgatattca
    79321 tatgtgtgtg tcgttctaat tgtcactgcc ttcttgatga tagagagtat tttagaatcc
    79381 agttctgggg ggtacaattt atttagagga aacagtagtc cagctattcc gtgttggaat
    79441 gataaattac ttacgaaatt tccaaattct gttgaagaag tgatccttcc ttcagaattt
    79501 acagttttat ctagtaaaaa tcgtagaaca ctattacatt ctgttttgta atcatattta
    79561 tgttcctcta tttttttaat tttgactaaa ttatttgttt gacttaaatt tagtagatat
    79621 tgtaaccaaa atagttgctc atctgtgagc tgaccttgag tatgtgatag ttctagtaat
    79681 tgaataggat cctttaggta gattcaatca atctataaca caacaacata ataatacttt
    79741 taggataact tgtcaaatat tatagtaaaa tgaaataata acaggacaaa ttgatc
//
LOCUS       DAVLTG010000004        68774 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLTG010000004 DAVLTG010000000
VERSION     DAVLTG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.004"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            359..1222
                     /locus_tag="VYN12_000250"
     CDS             359..1222
                     /locus_tag="VYN12_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1414699.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYDIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            1513..1710
                     /locus_tag="VYN12_000251"
     CDS             1513..1710
                     /locus_tag="VYN12_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV1414700.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            1778..2443
                     /locus_tag="VYN12_000252"
     CDS             1778..2443
                     /locus_tag="VYN12_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1414701.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSALVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIVGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            2515..3741
                     /locus_tag="VYN12_000253"
     CDS             2515..3741
                     /locus_tag="VYN12_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1414702.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4138..4215)
                     /locus_tag="VYN12_000254"
                     /pseudo
     CDS             complement(4138..4215)
                     /locus_tag="VYN12_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4286..4900
                     /locus_tag="VYN12_000255"
     CDS             4286..4900
                     /locus_tag="VYN12_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1414703.1"
                     /translation="MPTALGYVSIGLVCGIIGVPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVTAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAVLRLVF"
     gene            5004..5834
                     /locus_tag="VYN12_000256"
     CDS             5004..5834
                     /locus_tag="VYN12_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414704.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            5875..5952
                     /locus_tag="VYN12_000257"
                     /pseudo
     CDS             5875..5952
                     /locus_tag="VYN12_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            6056..6886
                     /locus_tag="VYN12_000258"
     CDS             6056..6886
                     /locus_tag="VYN12_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414705.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7040..7894
                     /locus_tag="VYN12_000259"
     CDS             7040..7894
                     /locus_tag="VYN12_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1414706.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            7994..9367
                     /locus_tag="VYN12_000260"
     CDS             7994..9367
                     /locus_tag="VYN12_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1414707.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9360..10421
                     /locus_tag="VYN12_000261"
     CDS             9360..10421
                     /locus_tag="VYN12_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1414708.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            10423..11115
                     /locus_tag="VYN12_000262"
     CDS             10423..11115
                     /locus_tag="VYN12_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414709.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11145..11714)
                     /locus_tag="VYN12_000263"
     CDS             complement(11145..11714)
                     /locus_tag="VYN12_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1414710.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPTPGTV
                     LLFIASIVIEALVGALIGQALSKKFAQKI"
     gene            11849..12463
                     /locus_tag="VYN12_000264"
     CDS             11849..12463
                     /locus_tag="VYN12_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1414711.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12465..14111
                     /locus_tag="VYN12_000265"
     CDS             12465..14111
                     /locus_tag="VYN12_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1414712.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14123..15409
                     /locus_tag="VYN12_000266"
     CDS             14123..15409
                     /locus_tag="VYN12_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1414713.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15461..15994
                     /locus_tag="VYN12_000267"
     CDS             15461..15994
                     /locus_tag="VYN12_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414714.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            16072..16542
                     /gene="nrdI"
                     /locus_tag="VYN12_000268"
     CDS             16072..16542
                     /gene="nrdI"
                     /locus_tag="VYN12_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1414715.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16835..18097)
                     /locus_tag="VYN12_000269"
     CDS             complement(16835..18097)
                     /locus_tag="VYN12_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1414716.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18407..18865)
                     /locus_tag="VYN12_000270"
     CDS             complement(18407..18865)
                     /locus_tag="VYN12_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1414717.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18862..19302)
                     /locus_tag="VYN12_000271"
     CDS             complement(18862..19302)
                     /locus_tag="VYN12_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1414718.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19508..21457
                     /gene="mutL"
                     /locus_tag="VYN12_000272"
     CDS             19508..21457
                     /gene="mutL"
                     /locus_tag="VYN12_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1414719.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21782..22249)
                     /locus_tag="VYN12_000273"
     CDS             complement(21782..22249)
                     /locus_tag="VYN12_000273"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1414720.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(22250..23455)
                     /locus_tag="VYN12_000274"
     CDS             complement(22250..23455)
                     /locus_tag="VYN12_000274"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1414721.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23475..24110)
                     /gene="ribE"
                     /locus_tag="VYN12_000275"
     CDS             complement(23475..24110)
                     /gene="ribE"
                     /locus_tag="VYN12_000275"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1414722.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24095..25195)
                     /gene="ribD"
                     /locus_tag="VYN12_000276"
     CDS             complement(24095..25195)
                     /gene="ribD"
                     /locus_tag="VYN12_000276"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1414723.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNGAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(25330..25444)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25601..26194
                     /gene="ruvA"
                     /locus_tag="VYN12_000277"
     CDS             25601..26194
                     /gene="ruvA"
                     /locus_tag="VYN12_000277"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1414724.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASVENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            26204..26767
                     /locus_tag="VYN12_000278"
     CDS             26204..26767
                     /locus_tag="VYN12_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1414725.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPVKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26764..27441
                     /locus_tag="VYN12_000279"
                     /pseudo
     CDS             26764..27441
                     /locus_tag="VYN12_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(27582..28613)
                     /locus_tag="VYN12_000280"
     CDS             complement(27582..28613)
                     /locus_tag="VYN12_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1414726.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLNFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDEIFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(28868..29551)
                     /locus_tag="VYN12_000281"
     CDS             complement(28868..29551)
                     /locus_tag="VYN12_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1414727.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPH
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29563..30507)
                     /locus_tag="VYN12_000282"
     CDS             complement(29563..30507)
                     /locus_tag="VYN12_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1414728.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            30639..33470
                     /gene="uvrA"
                     /locus_tag="VYN12_000283"
     CDS             30639..33470
                     /gene="uvrA"
                     /locus_tag="VYN12_000283"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1414729.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKNVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVDMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            33463..34524
                     /locus_tag="VYN12_000284"
     CDS             33463..34524
                     /locus_tag="VYN12_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1414730.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            34656..35054
                     /gene="spx"
                     /locus_tag="VYN12_000285"
     CDS             34656..35054
                     /gene="spx"
                     /locus_tag="VYN12_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1414731.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            35120..35689
                     /locus_tag="VYN12_000286"
     CDS             35120..35689
                     /locus_tag="VYN12_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1414732.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            35776..36042
                     /locus_tag="VYN12_000287"
     CDS             35776..36042
                     /locus_tag="VYN12_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1414733.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            36046..36465
                     /gene="ruvX"
                     /locus_tag="VYN12_000288"
     CDS             36046..36465
                     /gene="ruvX"
                     /locus_tag="VYN12_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1414734.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            36481..36786
                     /locus_tag="VYN12_000289"
     CDS             36481..36786
                     /locus_tag="VYN12_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1414735.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            37397..38647
                     /locus_tag="VYN12_000290"
     CDS             37397..38647
                     /locus_tag="VYN12_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1414736.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISIFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            38644..39174
                     /locus_tag="VYN12_000291"
     CDS             38644..39174
                     /locus_tag="VYN12_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1414737.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTG
                     QDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIV
                     VDDMDRDPSDQIVLTK"
     gene            39320..40852
                     /gene="cls"
                     /locus_tag="VYN12_000292"
     CDS             39320..40852
                     /gene="cls"
                     /locus_tag="VYN12_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1414738.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            41110..42648
                     /locus_tag="VYN12_000293"
     CDS             41110..42648
                     /locus_tag="VYN12_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1414739.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSLRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            42768..44975
                     /gene="nrdD"
                     /locus_tag="VYN12_000294"
     CDS             42768..44975
                     /gene="nrdD"
                     /locus_tag="VYN12_000294"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1414740.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            44987..45127
                     /locus_tag="VYN12_000295"
     CDS             44987..45127
                     /locus_tag="VYN12_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414741.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            45171..45677
                     /locus_tag="VYN12_000296"
     CDS             45171..45677
                     /locus_tag="VYN12_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1414742.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            45670..46260
                     /gene="nrdG"
                     /locus_tag="VYN12_000297"
     CDS             45670..46260
                     /gene="nrdG"
                     /locus_tag="VYN12_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1414743.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            46257..46874
                     /locus_tag="VYN12_000298"
     CDS             46257..46874
                     /locus_tag="VYN12_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1414744.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            47140..47448
                     /gene="rpsJ"
                     /locus_tag="VYN12_000299"
     CDS             47140..47448
                     /gene="rpsJ"
                     /locus_tag="VYN12_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1414745.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            47665..48291
                     /gene="rplC"
                     /locus_tag="VYN12_000300"
     CDS             47665..48291
                     /gene="rplC"
                     /locus_tag="VYN12_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1414746.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            48316..48939
                     /gene="rplD"
                     /locus_tag="VYN12_000301"
     CDS             48316..48939
                     /gene="rplD"
                     /locus_tag="VYN12_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1414747.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            48939..49235
                     /locus_tag="VYN12_000302"
     CDS             48939..49235
                     /locus_tag="VYN12_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1414748.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            49253..50086
                     /gene="rplB"
                     /locus_tag="VYN12_000303"
     CDS             49253..50086
                     /gene="rplB"
                     /locus_tag="VYN12_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1414749.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            50190..50471
                     /gene="rpsS"
                     /locus_tag="VYN12_000304"
     CDS             50190..50471
                     /gene="rpsS"
                     /locus_tag="VYN12_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1414750.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            50483..50827
                     /gene="rplV"
                     /locus_tag="VYN12_000305"
     CDS             50483..50827
                     /gene="rplV"
                     /locus_tag="VYN12_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1414751.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            50840..51493
                     /gene="rpsC"
                     /locus_tag="VYN12_000306"
     CDS             50840..51493
                     /gene="rpsC"
                     /locus_tag="VYN12_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1414752.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            51497..51910
                     /gene="rplP"
                     /locus_tag="VYN12_000307"
     CDS             51497..51910
                     /gene="rplP"
                     /locus_tag="VYN12_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1414753.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            51920..52126
                     /locus_tag="VYN12_000308"
     CDS             51920..52126
                     /locus_tag="VYN12_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1414754.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            52151..52411
                     /gene="rpsQ"
                     /locus_tag="VYN12_000309"
     CDS             52151..52411
                     /gene="rpsQ"
                     /locus_tag="VYN12_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1414755.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            52437..52805
                     /gene="rplN"
                     /locus_tag="VYN12_000310"
     CDS             52437..52805
                     /gene="rplN"
                     /locus_tag="VYN12_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1414756.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            52883..53188
                     /gene="rplX"
                     /locus_tag="VYN12_000311"
     CDS             52883..53188
                     /gene="rplX"
                     /locus_tag="VYN12_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1414757.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            53212..53754
                     /gene="rplE"
                     /locus_tag="VYN12_000312"
     CDS             53212..53754
                     /gene="rplE"
                     /locus_tag="VYN12_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1414758.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            53772..54041
                     /gene="rpsN"
                     /locus_tag="VYN12_000313"
     CDS             53772..54041
                     /gene="rpsN"
                     /locus_tag="VYN12_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1414759.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            54296..54694
                     /gene="rpsH"
                     /locus_tag="VYN12_000314"
     CDS             54296..54694
                     /gene="rpsH"
                     /locus_tag="VYN12_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1414760.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            54886..55422
                     /gene="rplF"
                     /locus_tag="VYN12_000315"
     CDS             54886..55422
                     /gene="rplF"
                     /locus_tag="VYN12_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1414761.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            55506..55862
                     /gene="rplR"
                     /locus_tag="VYN12_000316"
     CDS             55506..55862
                     /gene="rplR"
                     /locus_tag="VYN12_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1414762.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            55880..56374
                     /gene="rpsE"
                     /locus_tag="VYN12_000317"
     CDS             55880..56374
                     /gene="rpsE"
                     /locus_tag="VYN12_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1414763.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            56346..56570
                     /gene="rpmD"
                     /locus_tag="VYN12_000318"
     CDS             56346..56570
                     /gene="rpmD"
                     /locus_tag="VYN12_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1414764.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            56715..57155
                     /gene="rplO"
                     /locus_tag="VYN12_000319"
     CDS             56715..57155
                     /gene="rplO"
                     /locus_tag="VYN12_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1414765.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            57168..58478
                     /gene="secY"
                     /locus_tag="VYN12_000320"
     CDS             57168..58478
                     /gene="secY"
                     /locus_tag="VYN12_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1414766.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            58629..59267
                     /locus_tag="VYN12_000321"
     CDS             58629..59267
                     /locus_tag="VYN12_000321"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1414767.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDCLLERLSGRIIHRETGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFKDIEKVLTNLK"
     gene            59384..59602
                     /gene="infA"
                     /locus_tag="VYN12_000322"
     CDS             59384..59602
                     /gene="infA"
                     /locus_tag="VYN12_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1414768.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            59627..59743
                     /gene="rpmJ"
                     /locus_tag="VYN12_000323"
     CDS             59627..59743
                     /gene="rpmJ"
                     /locus_tag="VYN12_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1414769.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            59761..60126
                     /gene="rpsM"
                     /locus_tag="VYN12_000324"
     CDS             59761..60126
                     /gene="rpsM"
                     /locus_tag="VYN12_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1414770.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            60144..60527
                     /gene="rpsK"
                     /locus_tag="VYN12_000325"
     CDS             60144..60527
                     /gene="rpsK"
                     /locus_tag="VYN12_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1414771.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            60570..61505
                     /locus_tag="VYN12_000326"
     CDS             60570..61505
                     /locus_tag="VYN12_000326"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1414772.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIEGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEITAGDILTDSDVEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            61517..61903
                     /gene="rplQ"
                     /locus_tag="VYN12_000327"
     CDS             61517..61903
                     /gene="rplQ"
                     /locus_tag="VYN12_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1414773.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            62168..62434
                     /locus_tag="VYN12_000328"
     CDS             62168..62434
                     /locus_tag="VYN12_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1414774.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            62444..63781
                     /locus_tag="VYN12_000329"
     CDS             62444..63781
                     /locus_tag="VYN12_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1414775.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            64025..64717
                     /locus_tag="VYN12_000330"
     CDS             64025..64717
                     /locus_tag="VYN12_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1414776.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(64820..66455)
                     /locus_tag="VYN12_000331"
                     /pseudo
     CDS             complement(64820..66455)
                     /locus_tag="VYN12_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(66445..67536)
                     /locus_tag="VYN12_000332"
     CDS             complement(66445..67536)
                     /locus_tag="VYN12_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414777.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQTIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(67549..68670)
                     /locus_tag="VYN12_000333"
                     /pseudo
     CDS             complement(67549..68670)
                     /locus_tag="VYN12_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        20617 a        12901 c        15076 g        20180 t
ORIGIN      
        1 taaaatttgt acaaaaaaat gttaaatttt catagtatac tgtttaatag aaagtaggtt
       61 ctttgtaacc gctccattat aaaatccttt cactcttccg gtatactatt aggaaaaaca
      121 taactggagg atattttgag ctcacacctc atcgttccag tggctgttcc ccaagctcgt
      181 gtactgccca aaaaagttag acattctatt tagaacgagg attgagttct gtattgtaca
      241 aggctcggtc cttttagagt cagcttaagg ctggcttttt caatcaccaa agtgtcagaa
      301 tgttttgaca aatgaacaca aataatgata taatatgcaa aagctaggag gtggtaggat
      361 gattgaaaaa atggaactgg gggaatttta caaggaatta cgtttggcga gaaagcttaa
      421 gcagacagat gtggcttgtg agggtctaac agcttctcag ttgtccaagt ttgaactagg
      481 gcagtctatg ctgtctgcgg ataagttgat tctagctatc caaggtataa atgtgacctt
      541 tgatgagttt gggcacaagc tcaacaacta tcaagaatct ccacatatgc gaatcggtcg
      601 aaaggttgtg aatcgctttg cccatcagga tatagctgct ttagagcagc tattggagga
      661 agtcgatcaa gaacagatgg cgcagaccta tcgtcgtttg aatgccatcg tgattaaaga
      721 tgccatccat tcactaaata aaagctaccc actagcagag gaggatagcg agtttttgac
      781 cacctatctc tatgatatcg agtcttggac ctggtttgaa ctctatctct tttgcaatac
      841 catgcccttc ttgagcaatc aagatctgat ttttttatca acctccttac tcgaaaaatc
      901 caaagaattt aaagagttag tacacaatcg attgtatatg aagcaaggac tcttaaatat
      961 cttatcagaa ctcatggagc gaaaactttt ctcctacatc ccaatcttcg aagccgagtt
     1021 ggagaggatg ttacgaccgt atgatgtttt tgaaaaagta tcgtggcaat ttttaaagaa
     1081 gatgagtgtc tttcttcaaa caaagggaag caatcaaaaa gagattgaac gctttatcca
     1141 atctctgcag gtattagaaa atccacaatt aacatccctt tttgaattgc gttttcagca
     1201 atataaagaa cttatagatt agttaaaaat ggaatgacaa taacccactc cgaaataagt
     1261 aggagtatca gttggatttt tcttttcttc atctattata ttcctccttg ttagtaataa
     1321 ctttattata ccagggaaat aatcaaatct atcaaaatcg caaataagaa atttctataa
     1381 gaaaaaatat caaatatgcg attttttaaa ataagccaat tttcgtgtta tactgtactt
     1441 gtaaagcact tgaagcaaat cctaggtcgc agaagtggtt tacaaatgaa gataattgaa
     1501 ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa tggaattgac agaagctgag
     1561 ttggagacag tttatggagg ggaatttggg aataatgctg ttatcccagc cggtgcttgg
     1621 ggaggtttag gaacgtcttg gtcaatcact aatttctgga agaaatattt taaccatgat
     1681 tcttccactg ttaatcgtcg ccattattga tattcagagt ccttgccttt ttcttgggta
     1741 gggactgtct ttatttcata gtataggaga aaatagaatg aaaaagataa tctcacaccg
     1801 ctactttatt atagtttttc tactagttat tgctgaccag aagttcagtg ctctagtttt
     1861 acgcagtgac cttgttactg ggctatctga ctttgcctat tatctgtcgg atatgatgtt
     1921 gaattttctt gtggttttat ttgctcttat tgctatgatt tggtcgggga aatggcagaa
     1981 aatcaatagt agaaagttta aaggatccta tcttttctat tccttcctag ctctgcttgc
     2041 ttttgttgtt tggaatttcg ttaccttttt tcttttccca cctactcgaa atgaaatttc
     2101 ttatcaacat gctgctccga cttttacagg ggctacagca tttttgatgt attttttcta
     2161 tcctgtgatt gtaggtccca tttttgaaga gataatccat cggggattgg tgatgacagc
     2221 tctggaaaaa ggaaagaaat gggggctaga tgtacttggt tccgctgttt tatttggggt
     2281 ctcgcacatt agtaatcacg gttgggtctt gacagacttt ttcgtctata tgggtggcgg
     2341 acttatattt gcagtcttat ttagaatgac aaagtccatt tattggccta ttgggctgca
     2401 tatagtctac aacggtattg gtcagctttt gatgttactg taattttggt tgttagtagt
     2461 atcgcggtct atttctgggg aaagattccc atttgaactt aagaaggagt tgtgatgaaa
     2521 gtatttcttc aaaatagaga ttttaggcaa ttaactatca accagtggat ttcaacgctt
     2581 ggggatacga ttttttatct ggccttcctg aattatgtgg cagatgcgtc ttttgcccct
     2641 ttggcgattt tacttatcac gatttcagaa acccttcccc aagttctaca aatctttctg
     2701 ggagttttgg cggattttca acatcatcgt gtcttgaaat acacagtcat tagttttaca
     2761 aaatttttgc tttactctat agtgtcccta tcgctttcag ggcagtcttt ttccttgttg
     2821 ctagtaacct ttatttgtct gcttaacctc ttgtctgaca cattgagtta tttttcaggc
     2881 gccatgctca ctccgatttt cattagaatt attgggcaag accatctggc agaagctatt
     2941 ggatttaaac agtcaactgt tagtttagtg aaaacaatca gtaatatcct aggaggagtc
     3001 ttactaggca ttctatccat ccagtttatt tccttactga acgctcttac ctttttaatc
     3061 gcatttttag gtatcctctt cataaaaact gacctcttga aagtagaaaa aacgattagc
     3121 tatcaagaag gactctctgt aaaatccttt tgccagcatt tgctccaatc atcgaaattg
     3181 atatggaata tgaataaggt gctcttggtt ttgtttatta tctctactag tcaagcagtg
     3241 ataaatgtta cggttcctat ttccactcta tttttaagga accagccctt tttgaattta
     3301 caaactggtc aatctcttgc cttgttagcc acactagaat tatcagccct tattttggga
     3361 agtcttatga gtggctatct gcaacatacc atttccataa aaacagctct ctatgcctca
     3421 cttgttatcc agttgcttct tctagtagga tttgccacag ttcgttttga ctggattctc
     3481 atctttagta ccttggatgc ctttttcgcg ggtattctct ctcctagatt gcaagaactc
     3541 gtctttaaac aaatacctga ggagtcaatg ggagcagttc aatcttctat cggtgccatt
     3601 acggttgtct tacctagctt atttacaata gctttggtaa ccattgctac cagctttgga
     3661 actctggcag ttagctttgt tttattgcta tttcttctag ttgcctttgt catgcttctg
     3721 aatattcgtg aaagtattta gtggagaatt tctataaaat atgtttgaga ctggattgcc
     3781 agtcttttta tgatggtcaa aatcaacaga cttttttctc ttttctgaat gtgttatagt
     3841 agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact
     3901 ttcccaatcg atttgttctc atcttatttc aatctgctat ataatagtcc atgctgtggc
     3961 tggattcttt tcagcctact tgtactcttc gaaactctct tcaaaccacg tcagcttcac
     4021 cttgccgtag gtatggttac tgacttcgtc agttctatcc acaacctcaa aacggtgttt
     4081 tgagctgact tcgtcagttc tatccacaac ctcaaaacag tgttttgaac tgacttcgtc
     4141 agttctatcc acaacctcaa aacaatgttt tgagcaacct gcggctagtt tcctagtttg
     4201 ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga aagaaaaagg
     4261 attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca gtatcggcct
     4321 ggtctgtgga attatcggtg tgccctatgt gacacttgtt gagatgggct tgatgagtct
     4381 ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg ttcaagctcc
     4441 tgtgacagct attgctatga cggtttttct aatcaacttg cgtctctttt tgttgagttt
     4501 acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta tgtctagtat
     4561 cttgacagat gagacctatg gcgttttgat gggcgaatta gcccatacag acaaggtaaa
     4621 tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg tggggacagt
     4681 agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct tgattctttc
     4741 aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag acttcttagc
     4801 cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa cagttctctt
     4861 tggagtagtc ttgattgccg tcttgcgttt ggtcttttaa atcagccata aagaaaacct
     4921 atcacagata tatatatcat ataatggtgt aaatgatttt tttctgttaa gattataagg
     4981 tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct cttgctgccc
     5041 tagggcttgt tgctgcaggt gtgctagcag cttgctcagg tggtgctaag aaagaaggac
     5101 aagcagctag caagaaagaa attattgttg caactaattc ttcaccaaaa ccattcaact
     5161 atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct atctttaaag
     5221 actctgacaa gtatgatgtc aagtttgaga agacagagtg gtcaggtgtc tttgcgggtc
     5281 ttgacgctga ccgttaccaa atggctgtta acaatatcag ctacactaaa gaacgtgcgg
     5341 agaaatacct ttatgcagcc ccaactgtta aagaccctaa cgttcttgta gtcaagaaag
     5401 acgattctag catcaaatcg cttgatgatg ttggtggaaa atcaacagaa gttgttcaag
     5461 gaacaacttc tgctaaacag ttagaagact acaacaaaca acactcagat aatccaacta
     5521 tccttaacta tactaaagca aacttacaac aaatcatggg ccacttgagc gatggtcagt
     5581 ttgactacaa gatttttgat aaaatcactg ttgaaacagt catcaagaac caaggtttgg
     5641 acaacttgaa agtcatcgat cttccaagcg accaacaacc gtacgtttac ccacttcttg
     5701 ctaaaggtca agatgagttg aaaacatttg tagacaaacg tatccaagaa ctctacaaag
     5761 acggaactct tgaaaaattg tctaaacaat tcttcggaga cacttaccta ccggcagaag
     5821 ctgatattaa ataatttctt gaaatcatcc attctgagta agatgggtga tttttcagtt
     5881 cgctactgca atctagtcgg aacagttctc tttggagtgg tcttgattgc catcttgcgt
     5941 ttggtctttt aaattaccca taaaaaaaac ttatcacaga gatagatatc atataatggc
     6001 gtaaatgctc tttttctgtt aagattataa ggtattctat tttggaggaa atgacatgaa
     6061 aaaaatcgtt aaatactcat ctcttgctgc cctaggactt gttgctgcag gtgtgcttgc
     6121 ggcttgctca ggtggtgcta agaaagaagg agaagcagct agcaagaaag aaatcatcgt
     6181 tgcaaccaat ggatcaccaa ggccatttat ctatgaagaa aatggcgaat tgactggtta
     6241 cgagattgaa gtcgttcgcg ctatctttaa agattctgac aaatatgatg tcaagtttga
     6301 aaagacagaa tggtcaggtg tctttgctgg tcttgacgct gaccgttaca atatggctgt
     6361 caacaatctt agctacacta aagaacgtgc ggagaaatac ctctatgccg caccaattgc
     6421 ccaaaatcct aatgtccttg tcgtgaagaa agatgactct agtatcaagt ctctcgatga
     6481 tatcggtgga aaatcgacgg aagtcgttca agccactaca tcagctaagc agttagaagc
     6541 atacaatgct gaacacacgg acaacccaac tatccttaac tatactaagg cagacttcca
     6601 acaaatcatg gtacgtttga gcgatggaca atttgactac aagatttttg ataaaatcgg
     6661 tgttgaaaca gtgatcaaga accaaggttt ggacaacttg aaagttatcg aacttccaag
     6721 cgaccaacaa ccgtacgttt acccacttct tgctcaaggt caagatgagt tgaaatcatt
     6781 tgtagacaaa cgcatcaaag aactttataa agatggaact cttgaaaaat tgtctaaaca
     6841 attcttcgga gacacttatc taccggcaga agctgatatt aaataatttc ttgaaatcat
     6901 ccattctgag taaggtgggt ggtttctcag tttttaggga tatagtttta aactatatat
     6961 ctgactatct aataacaatt tgtgaaatca aacaaattgt gagatactag tacggtatta
     7021 tttttaagga gaaagaatca tgaaaatcaa aaaatggctt ggcctagcag cccttgctac
     7081 agtcgcaggt ttggctcttg cagcttgcgg aaactcagaa aagaaagcag acaatgcaac
     7141 aactatcaaa atcgcaactg ttaaccgtag cggttctgaa gaaaaacgtt gggacaaaat
     7201 ccaagaattg gttaaaaaag acggaattac cttggaattt acagagttca cagactactc
     7261 acaaccaaac aaagcaactg ctgatggcga agtagatttg aacgctttcc aacactataa
     7321 cttcttgaac aactggaaca aagaaaacgg aaaagacctt gtagcgattg cagatactta
     7381 catctctcca atccgccttt actcaggttt gaatggaagt gccaacaagt acactaaagt
     7441 agaagacatc ccagcaaacg gagaaatcgc tgtaccaaat gacgctacaa acgaaagccg
     7501 tgcgctttac ttgcttcaat cagctggctt gattaaattg gatgtttctg gaactgctct
     7561 tgcaacagtt gccaacatca aagaaaatcc aaagaacttg aaaatcactg aattggacgc
     7621 tagccaaaca gctcgttcat tgtcatcagt tgacgctgcc gttgtaaaca ataccttcgt
     7681 tacagaagca aaattggact acaagaaagc acttttcaaa gaacaagctg atgaaaactc
     7741 aaaacaatgg tacaacatca ttgttgcgaa aaaagattgg gaaacatcac ctaaggctga
     7801 tgctatcaag aaagtaatcg cagcttacca cacagatgac gtgaaaaaag ttatcgaaga
     7861 atcatcagat ggtttggatc aaccagtttg gtaataagaa acagggaggt gggagagaaa
     7921 attccacctc ttgcttttgt atagagtata gattgtaaag aagactattc gttcatagaa
     7981 aggtagagag aatatggttt ttcctagcga acaagaacag attgaaaaat ttgaaaagga
     8041 tcatgtagcc cagcattatt ttgaggtttt gcgtaccttg atttctaaga aatcagtctt
     8101 tgcccagcag gttggactca aggaagtcgc aaattatctg ggtgagattt tcaagcgtgt
     8161 tggagctgaa gtggagattg atgagagcta tacagcgccc tttgtcatgg cacatttcaa
     8221 gagttcgcgt ccagatgcca agaccttgat tttctataac cactatgaca ctgtgccagc
     8281 ggatggggat caggtctgga cagaggatcc ttttacgctt tcggtccgca atggcttcat
     8341 gtatgggcgt ggggttgatg acgacaaggg tcatatcaca gctcgcttga gtgctttgag
     8401 aaaatatatg cagcaccatg atgatttacc tgtcaatatc agctttatca tggagggagc
     8461 ggaggaatcg gcttcaacag acctagataa gtatttggaa aagcatgcag acaaactccg
     8521 tggggcggat ttgttggtct gggaacaagg gaccaaaaat gccttggaac agctggaaat
     8581 ttctggtggc aataagggga ttgtgacctt tgatgccaag gtaaaaagcg ctgatgtgga
     8641 tatccactcg agttatggtg gtgttgtgga atcagctcct tggtatctcc tccaagcctt
     8701 acagtctctt cgtgctgcgg atggccgtat cttggttgaa ggcttgtacg aagaagtaca
     8761 agagcccaat gaacgagaaa tggccttgct agaaacttat ggtcaacgaa acccagagga
     8821 agttagtcgg atttatggat tggagttgcc tctcttacag gaggagcgga tggcctttct
     8881 aaaacgtttc tttttcgagc cagcgctcaa tatcgaagga atccagtctg gttatcaagg
     8941 tcagggtgtt aagactattt tacctgcaga agccagtgcc aagctagagg ttcgtctggt
     9001 tccgggccta gaaccgcatg atgttctgga aaaaattcgg aaacagctag acaaaaatgg
     9061 ctttgataag gtagaattat actatacctt gggagagatg agctatcgaa gcgatatgag
     9121 cgcaccagcc attctcaatg tgatcgagtt ggccaagaaa ttctatccac agggcgtttc
     9181 agtcttgccg acgacagcgg ggacaggacc tatgcatacg gtctttgatg ccctagaggt
     9241 accaatggtt gcattcggtc taggaaatgc caatagccga gaccacggtg gagatgaaaa
     9301 tgtgcgaatc gctgattatt acacccatat cgaattagta gaggagctga ttagaagcta
     9361 tgagtagaga tattatcaag ttagatcaga tcgatgtgac ttttcaccaa aagaagagaa
     9421 ccatcacagc ggttaaggat gtgaccattc acatccaaga aggggatatc tacggaatcg
     9481 ttggatattc tggagcagga aaatcaaccc ttgtacgggt gattaatctc ttgcaaaaac
     9541 catctgcagg gaaaattacc attgacgatg atgtgatttt tgacggcaag gtgaccttga
     9601 cggcagagca gttgcgtcgt aaacgtcaag atatcggaat gattttccag cattttaacc
     9661 tgatgagcca aaagacagca gaggagaatg tagcctttgc ccttaaacac tctgaactca
     9721 gcaaggaaga aaagaaggct aaagtagcta agttgttgga cttggttggt ttggcagatc
     9781 gtgctgaaaa ctacccttca caactatctg gagggcaaaa acagcgtgtg gccattgcgc
     9841 gtgccttggc caatgatcca aaaatcttga tttcagacga gtcaacttct gcccttgatc
     9901 cgaagacaac caagcagatt ttggccttgt tgcaagattt gaaccaaaaa ttaggcttga
     9961 ctgttgtctt gattacgcat gaaatgcaga ttgtcaaaga cattgccaac cgtgtggcgg
    10021 ttatgcagga tgggcatttg attgaagagg gtagtgtgct tgaaatcttc tcagacccta
    10081 aacaaccttt gactcaagac tttatctcaa cagctacagg tattgacgaa gccatggtca
    10141 aaatcgagaa gcaagaaatc gtggaacact tgtctgaaaa cagtctcttg gtgcaactca
    10201 agtacgctgg agcttcaaca gacgagccac ttttgaatga attgtacaag cattaccaag
    10261 taatggctaa tattctctat gggaatatcg aaattctcga tggtactcct gttggagaat
    10321 tggtggtggt cttgtcaggt gaaaaagcag cgttggcagg tgcccaagaa gccattcgtc
    10381 aagcaggtgt acaactaaaa gtattgaagg gagtacagta agatggaatc attgattcaa
    10441 acctatttac caaatgtcta taaaatgggt tgggctggtc aggcaggctg gggaacggct
    10501 atctacttaa ctctttatat gacagttctt tccttcatta tcggaggctt cttggggcta
    10561 gtggcaggtc tctttctcgt cttgacagcg ccaggtggtg tcttggagaa taaagtcgta
    10621 ttctggattt tagacaaaat tacctcaatt tttcgtgcgg ttccctttat catcctcttg
    10681 gcaatcttgt caccactttc tcacttgatt gttaaaacaa gtatcgggcc aaatgcagcc
    10741 cttgtcccac tttcttttgc agtctttgcc ttctttgccc gtcaggtgca ggttgtcttg
    10801 gctgaattgg atggcggtgt cattgaggcg gctcaagcga gcggagcgac tttctgggac
    10861 atcgtgggtg tttacctatc agaaggtctt ccagatttga tccgtgtgac gactgtgacc
    10921 ttgatttccc ttgttgggga aacagctatg gccggtgcgg ttggagctgg tggtatcggt
    10981 aacgtagcca tcgcttatgg atttaaccgc tacaatcacg atgtgaccat cttggcaacc
    11041 attattatca ttttgattat ctttgcaatc caattcttgg gagatttctt gactaagaaa
    11101 ttgagccata aataaaaaag agccgcgtgg ctctttttaa ctgatcagat tttctgtgca
    11161 aattttttac tcaaggcttg tccaatcaag gcacccacta gggcttcgat gacaatactt
    11221 gcgataaata gaaggacagt tccaggggtt ggagcgacca tgatacggtc gatatattct
    11281 tgggattttc ctcttgccag aagagtagcc atataggctt tgggcgcaat ccacataagc
    11341 aagattggtc ctgttgtact aaaggcgaaa ataatgaaag aaaggaagtt ctttgttttg
    11401 tccttgtatt ttcctaaatg agctactcca tctgctagga ggccacagat aattccagga
    11461 aggaaggaac cagcaccgtg tttagttccc aagaaaaaga gggcaatgac aaggccgata
    11521 gtggtaatgg ctccaaagcg cggaactttt gcgactagga tcatatagac gctaccgccg
    11581 acaagggcag taaaggcagg cgcataaaac atgtttccag tttggtcaaa gagattgccc
    11641 aaaaggacac caatccccat gcagaggaag taaagaactg caaaaagcag tgtagttaag
    11701 atagatttct tcatgaattg tctcctgata attttttcac aattctcatt ttaccatggt
    11761 ttggtgggat tgtaaatgga tactagaagt ttttgaaaac gcttgaaata tgatataatg
    11821 gtttcatagt tatttttagg ggaatatcat gggtagattt ttagactttg tctttaatcg
    11881 tttcttttta gggatgattg cgacagcctt cttttggcta ttaactttag caggagggat
    11941 tatccttggt ctagcgccgg ctagtgccac cttgatgagc ttatatgcag aacatggtta
    12001 tagctttcgg gaatacagtt tgaaggaggc ttggtctctt tacaagcaaa attttgtctc
    12061 aagcaacctg attttctata gctttttagg tgtgggtcta gttttgacct atggtttgta
    12121 tctattggtg caattacctc atcagaccat tgttcatttg attgcgaccc ttttgaatgt
    12181 cctagtagtt gccctgatct ttttggctta tacagtatct ttaaaattac aagtttattt
    12241 tgccttgtcc tatcgaaata gtctcaaatt atccttgatt ggcatcttta tgagtctagc
    12301 agctgtggcc aaggttctcc ttgggactgt gctacttgta gcaattggtt actatatgcc
    12361 tgccctgcta ttttttgtag gaattgggat gtggcatttc tttatcagtg atatgttgga
    12421 acctgtctat gaaatcatcc atgaaaaatt ggcgacaaaa tagaatgaag cagttttggc
    12481 tacatacgct tctaagaacc tatagttcag tgatgatcat tatcattgcg agttttgcaa
    12541 tcttactctc ttacgctgac tgggattcac gtgaaaagga agcccagaga gtagcccagc
    12601 gtgtaactgc tagaacagtg agtgaaattg aatattacca tagagagtca acccagatag
    12661 ctcaggcttt agttgaaaat caagctcgta ttgagggaat ctataaatac tttagcctta
    12721 gcatgccaga ctatttttac tggcaattag agcggaaagc ttcgccttat atatcagtct
    12781 ctctgtatga aaatgttgat gacctctatg ttcgaaatga ttttgtaact ggagtggcca
    12841 ttgcttttca agattacaag gaagtctatg tttctactaa agacaaacgt agtggagaaa
    12901 aaatcagggc tgaggatttc aaaccagcag gaaatagttt tgccattccg gtgtcagatc
    12961 cagtgtcaga tcaagattta ggagtgattt acatctcctt ggatcctgct gttttatacc
    13021 atgccattga taatactaga ggtcatactc cgatggcagt aacagtgacc tcaccttttg
    13081 atacggagat ttttcatatt ggtgagacag ttgataagga gagtgaaaat tggctagttg
    13141 gcttaacttc tcatggatat caggttcagg tggcagttcc taaaaacttt gttttacaag
    13201 gaacagtgac tagctctgct ttgattgtgg gtttgagcct tctctttatt gtcattcttt
    13261 atctgacttt gaggcagact tttgctaatt accaaaagca ggtagtggat ttagtagaat
    13321 ccattcaagt cattgctcaa ggcgaagagg ggcgtcggat tgacatttcc gagaaagatc
    13381 aggaattact cctaatcgcg gagacgacca atgatatgtt ggatcgattg gaaaagaata
    13441 tccatgatat ttaccagtta gagcttagtc aaaaagatgc caatatgcga gccttgcagg
    13501 cgcaaatcaa tcctcatttt atgtataata cgctggagtt cttgcgcatg tatgcagtta
    13561 tgcagagtca agatgagttg gcagatatca tttatgaatt cagtagtctc ttgcgtaaca
    13621 atatttccga cgaaagagag accctcctca aacaggaatt agaattttgc cgtaaataca
    13681 gctatctctg catggttcgc tatcccaagt ccattgccta tggtttcaag atagatccag
    13741 agttagagaa tatgaagatt cccaagttta ccttgcaacc gctggtagaa aactatttcg
    13801 cgcatggtgt tgaccacagg cggacagata atgtgattag catcaaggct cttaaacagg
    13861 atggttttgt ggaaattttg gtggtcgata atggtagagg aatgtcggct gaaaagttgg
    13921 caaatatccg agaaaaatta agtcagaaat attttgaaca ccaagccagc tacagtgatc
    13981 aaaggcagtc tatcgggatt gtcaatgtac acgagcgttt tgtgctctat tttggagacc
    14041 gctatgccat tactatagag tctgcagagc aagccggtgt tcagtatcgt attacaattc
    14101 aagatgagta gaaagggaga aaatgtataa agtattatta gtagatgatg agtacatggt
    14161 gacagaaggt ctgaagcgtt tgattccctt tgataagtgg gatatggagg tcgtcgcaac
    14221 agccagtcat gccgatgaag ctctagaata tgttcaggaa aatcctgtcg atgtcatcat
    14281 ttccgatgtc aatatgccag acaaaacagg gcttgatatg attcgggaga tgaaagagat
    14341 cttaccagat gctgcctata tcctgctctc aggttatcag gagtttgatt atgtaaaaag
    14401 agcaatgaac cttagtgtgg tggactattt ggtcaagcct gttgataagg tagagctggg
    14461 aaatctgctg gagaagattg caggtcagct cggcgagaga gggaagaaaa gtcagactct
    14521 tagtcaagaa ttagacgagg ctggatttgt tagttattta ggggataagg agaattggtg
    14581 gataggtcta tccaaggaaa aacaaggttc cttcaccatt ccctactatg tcttgggcca
    14641 agactggcag attttcattt ctgaccaacc cctagatggt ttagtcgtta caccttttga
    14701 agctccttat caagaacact ttgaacgctg gaagctgaat gctgagaaaa ccctctttta
    14761 cggttctgta aatttgcagc agtctgagag tctctttgcc tattacgaac cgatttatag
    14821 ggttattatt cagggaaatc tcaatcaaat cgtagaagag ttaaatctct tggagaaggt
    14881 agttcttgaa aatacgccgc gtgttccgat tactaaacag ctttttattc agtttgtcat
    14941 ggatgttttc catttatttg aacatctcaa agctgatgac ctgacagaca tcgtcaaaac
    15001 cattcatgct attcaatcct tcgatgaatt ggttccttat atcaaggaaa ctctgagcag
    15061 ctttttcggt caataccgta tgaatgaaaa tgtggtcagt gtgctggaag tcattggtcg
    15121 tgattaccaa aaagagcttt ccctcaagga tatcagtaag gctctcttta tcaatcctgt
    15181 ctatctaggg cagttgatta agcgtgaaac cgattcgact tttgcagagt tactaaacaa
    15241 acaacgtatt aaggctgccc aacaactttt gctttcaact agtgacagca tcgaagatat
    15301 ttgttatgct gttggttaca gtaaccttgg atatttctat aaagttttcc gaaaattgtg
    15361 cggaaaatcg ccaaaagcct accgaaaaca ggtagaaact atactataag atttgtattc
    15421 ctttacaaaa ggtgctataa tattatcagg aggtcctatc atgaaaaaga aaccaattta
    15481 tctatgggtc ttgctaatct tgtctgccct tatttcagtt ccgtctctgt ttggaattgt
    15541 gagtcccttg cctagtaaag aagcccttcg tgctgctcag aaacaagttg caggggtcaa
    15601 tgctcagcaa ttagaagacc agcttaatta tacctataga gtagcagaag catctcattc
    15661 tatttttaat gttgctttga ttgtgctatc tactatttta gtggtcgtag cgattgtctt
    15721 ccttgttcgt aaaaatttgc aatatgcaaa ctatacttac gttggctatg ttttgttagc
    15781 tattattggt tcgatttatg gctatgttgg tttacaagac gctgtgcagt tggttcaaga
    15841 tgagagcatg cgtttgacag tgagtattgg ttcaaaagct gttagcattt tctatatcgt
    15901 catcaatgtt ctcttcctag cccttgtctt ctataagatg tggcgacaac agaaagcctt
    15961 ggcagaagaa gaggaaacag aagagcttac ctaagtattg acaaaaaaga actatcaaga
    16021 tacaatcttg gtagttgttt tttgattata gataaaatca tggaggtaca tatgaagaca
    16081 atttctttag tttatattag tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa
    16141 gactatctct tgtcccagta caaagggatt gaggttcaaa agattcatat caaggatttg
    16201 gtcaaggaag gcaaaaattt ctatgaaatg gaccatccct atgtcgcttt tttgccgacc
    16261 tatctcgaag gtgggaatgg cgtggataac ggagatgttg agattttgac gacaccggtg
    16321 ggagatttta ttgcctatgg taacaatgct agtaagtgtt ttggtgtggt tgggtcagga
    16381 aatcgtaact ttaataacca atactgccta acagccaagc aatacagtca acgctttggc
    16441 ttccctgtat tggctgactt tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca
    16501 gctattatcg cagatttgta tgagttggaa aaggagaatt aatactcaat gaaaatcaaa
    16561 gagcaaacta ggaagctagt cgcaggttgc tcaaagcaca gctttgaggt tgcagataga
    16621 gctgacgtgg tttgaagaga ttctcgaata gtataaagtt cttataagat gtggttgaag
    16681 ttgttcaact gttttttgag tataaacagt ctttaagaac gtaaaaaagc ataagttcag
    16741 gtcttcaaaa ccttgttctt atgcttttta tcatagaaat atttgctgaa ttttctcttg
    16801 aaatgaaacc ttatcttcat ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg
    16861 cgtagataaa gaagatggcg aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt
    16921 tgagccaaga aggaagattt ttgttttcac gtgttaccaa ggcgtaattc aaaagagcaa
    16981 agaaaggtgt tgtcaggaaa gagccaatca tggcaaagcg gagcatggtt gaaacctgac
    17041 cagcgaagaa cttgataatg acgataccga tgatagcagt gatggtcatc cagatgttca
    17101 aagatttacg attgtcctct ttttgactga ttagcagtcg gagagattcc tgattaacgc
    17161 gagaatagcc atcgataaca gttataactg ttccaaagat acagaggaag gcaataaagg
    17221 taatcaagta acgggaccat tcgccaagaa cagaggcata catgcccacg aattgagaga
    17281 tgtatttggc tgaagcagct tcaaccgcct gccctgtagg atactgaatc agtgctccca
    17341 gtgccacaaa gaagacggct aggatagctg ttccaatata accagtgtta aagtcaaaca
    17401 gagcgtcttc tgtgttaaag ttgacggtct ttctcttttc agctgaccaa agtgaattga
    17461 tggctgaaat ttcaatagga gccggcatcc atcctaggag ggagacgatg aagggcagag
    17521 ctgccatttg ccaaggtgtc ttctcgacaa aatcagaact gtattctgga tgcttgaccg
    17581 ccgcaatgat aactgcaaga acagtcgcaa tggttaaggc agacataatc catttgacca
    17641 tgccgtctaa aagtttgtag cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa
    17701 tgagggacca ctgagtaatg ctaagtccaa tcattgggaa ggcactggcg atgatagctg
    17761 agcacagaat ggcaacacca gccgtgttga ccatagccga aaagacattg agaataaaga
    17821 aaatccagag atagagtttt cctttttcgg cataaccttc aaccaaagtc tttccagtat
    17881 cagctgtgta ttcagcacca aaacggaaaa atggatattt aaagacattg gctaagatga
    17941 ccaagagaag tagagaccaa ccgtaagaac cgccagcttg agttgaggat acaatgtggg
    18001 aacctccaac agcggcagtt gccattagga ttccaggtcc cattgctttt agcttgcttg
    18061 cccaggttga ttgatttaag gaaatagctt gcgacatgat aaatactcct ttttgaattt
    18121 tcagaataat ctgtatatgc aatctatatt ctacaaaaaa ttttggaaaa atgcaagaat
    18181 attttgaaaa aagatagaaa atttacaaag aaaatctgaa ataactgtta tgatatagca
    18241 gattgaaact agaatagtac acttttgctt ctaaaacatt gttagaaatc gatttgactg
    18301 tcctgattga tttatcctgt tcttatttca tttcactata gtaaggtgca gcaggataaa
    18361 gcaaaaccga gaagtttctt tctcggtttt gcttattatg aggttcctat tttctatgct
    18421 ccaagagttg attgatgtga tctacttttt tagcctctct tttatagaga atagcccaga
    18481 tgatgagata gacaatcgca aactcgataa tgagctggag gtagaaaatc cagtggaagg
    18541 ggaaccaacc agcaagagtt gctagtggga caaagccagc cagcataagg aagaaatgag
    18601 tcagagtggc acgaagcatg ctccagtcac ggctgaataa gcggttgcca aagttgaaga
    18661 gcataccgat ggctgcccag ataagtgtgc agtagagcaa gaccagggca ccgtgaacct
    18721 gatgctgatc catcacttgg ccgatgagag agtagggatt tagtggtgcg taggtatttg
    18781 gtgcataaat gagtgaaaag aggatggaga ggatgaggcc gataagaaca ccggcagctg
    18841 catcgtgaaa tacttgtttt ttcatagttc taatttctcc ttgatggttt ttagataacg
    18901 gcgtgaagag taggtgaagc tttcgttttt caagaaaatt tctaccagac cgtttggcgt
    18961 gagcttgagg tgagagatgg aatcgatatt gatgatttct gattgggaaa tttggataaa
    19021 attgcttggc aagagtttaa gaacctgata gagtcgcaaa tcaatgctgt aggtctgact
    19081 cgcggtttct gctagaacct tccgattctc gatatagaag cgctgaatct tgccaatctc
    19141 aactagatag acctgatcat cgatttttcc tttgattttt tctctttggt ccagattttc
    19201 tgcgaactcg atgactttct ggactttttc ggtttcttga ggtgcttgga caatcagctt
    19261 ttcctcctcg taagtctcac taatctgtag ttctactttc atagttttct ctccttttca
    19321 gttatacaag gttgtgatca cttcctgtat atccttatta aacactattt tatagcccat
    19381 ggcaaggaac cttgtctatg tggagggatt gggctcctat gtggtggagc ttttctgttc
    19441 tttctgaaat atggtataat agcactaatt aatttctagg aaaatagata cagaaagggg
    19501 ctgaaagatg tctcatatta ttgaattgcc agagatgctg gcaaaccaaa tcgcagctgg
    19561 agaggtcatt gaacgtcctg ccagtgtggt caaagagttg gtagaaaatg ccattgacgc
    19621 gggctctagt cagattatca ttgagattga ggaagctggt ctcaagaagg ttcaaatcac
    19681 ggataacggt catggaattg cccacgatga ggtggagttg gccctgcgtc gccatgcgac
    19741 cagtaagata aaaaatcaag cagatctctt tcggattcgg acgcttggtt ttcgtggtga
    19801 agccttgcct tctattgcgt ctgttagtgt cttgactctg ttaacggcgg tggatggtgc
    19861 tagtcatgga accaagttag tcgcgcgtgg gggtgaagtt gaggaagtca tcccagcgac
    19921 tagtcctgtg ggaaccaagg tttgtgtgga ggatctcttt ttcaacacgc ctgcccgtct
    19981 caagtatatg aagagccagc aagcggagtt gtctcatatc attgatattg tcaaccgtct
    20041 gggcttggcc catcctgaga tttcttttag cttgattagt gatggcaagg aaatgacgcg
    20101 gacagcaggg actggtcaac tgcgccaagc aatcgcaggg atttacggtt tggtcagtgc
    20161 caagaagatg attgaaattg agaactctga cctagatttc gaaatttcag gttttgtgtc
    20221 tttacctgag ttgactcggg ctaaccgcaa ttatatcagc ctcttcatca atggccgtta
    20281 tatcaagaac ttcctgctaa atcgtgctat tttggatggt ttcggaagca agcttatggt
    20341 tggacgtttt ccactggctg tcattcacat ccatatcgac ccttatctag cggatgtcaa
    20401 tgtgcatcca actaagcaag aggtgcggat ttccaaggaa aaagaactga tgaccctggt
    20461 ttcagaagct attgcaaata gtctcaagga acaaaccttg attccagatg ccttggaaaa
    20521 tcttgccaaa tcgaccgtgc gcaatcgtga gaaggtggag caaactattc tcccactcaa
    20581 agaaaatacg ctctactatg agaaaactga gccgtcaaga cctagtcaaa ctgaagtagc
    20641 tgattatcag gtagaattga ctgatgaagg gcaggatttg accctgtttg ccaaggaaac
    20701 cttggaccga ttgaccaagc cagcaaaact gcattttgca gagagaaagc ctgctaacta
    20761 cgaccagcta gaccatccag agttagatct tgctagcatc gataaggctt atgacaaact
    20821 ggagcgagaa gaagcatcca gcttcccaga gttggagttt ttcggacaaa tgcacgggac
    20881 ttatctcttt gcccaagggc gagatggact ttacatcata gatcagcacg ctgctcagga
    20941 acgggtcaag tacgaggagt accgtgaaag cattggcaat gttgaccaga gccagcagca
    21001 actcctagtg ccctatatct ttgaatttcc tgcggatgat gccctgcgtc tcaaggaaag
    21061 aatgcctctc ttagaggaag tgggcgtctt tctagcagag tacggagaaa atcaatttat
    21121 tctacgtgaa catcctattt ggatggcaga agaagagatt gaatcaggca tctatgagat
    21181 gtgcgacatg ctccttttga ccaaggaagt ttctatcaag aaataccgag cagagctggc
    21241 tatcatgatg tcttgcaagc gatctatcaa ggccaatcat cgtattgatg atcattcagc
    21301 tagacaactc ctctatcagc tttctcaatg tgacaatccc tataactgtc ctcacggacg
    21361 tcctgttttg gtgcatttta ccaagtcgga tatggaaaag atgttccgac gtattcagga
    21421 aaatcacacc agtctccgtg agttggggaa atattaaaag tataaaaaag tctgggaaaa
    21481 attttcaaaa tcaaaaaaac gcataaaatc aggtgttcaa aaaccttgat tttatgcgtt
    21541 ttatcatgga aatagttact tcattttttc ctaattcttt tcgaaactct ttttaaacga
    21601 cgtcagtttt atcagtaatc tcaaaacagt gttttgagct aattttgcca gttttgtctg
    21661 taacatcgaa gttgtgtttt accactctgc gactggtttc ctagtttgct ctatgatttt
    21721 cacagagtat taaattgcga ttttgccaag tttctttatt cgtctaaaag tagagtctgt
    21781 tctatgcgtc taatgtacga attaggttga ccatttcaat agctccttgt gcacactcag
    21841 aacccttatt tcctgcttta gtaccagctc gttctatggc ttgttcaatt gtatctgtcg
    21901 ttagcacacc aaacataaca ggaatttcgc tatttaaact gatttgggcg attcccttag
    21961 atacctcgct acatacataa tcataatgac ttgtatttcc tctaatgaca gctcccaagc
    22021 agataattgc atcatatttt ttactttttg ccatttttga tgcaatcagt gatatttcaa
    22081 aagctcctgg aacccaggct acctcgatat ctttctcgtt tacattctct cttttgagat
    22141 tatctagtgc tccagataat aattttgaag ttataaattc attaaatctc gctacaacaa
    22201 tacctatttt aatattgttt gctactaaat taccttcata agtgttcatt tatttttcct
    22261 ccatatttaa aatgtgaccc attcgatttt tctttgtttc taaataaaaa ctatcgtaag
    22321 gattggcttc tatttcgatt gatattctac tggaaatggt aattccatat ttttctaact
    22381 gttcaacctt gtcaggatta tttgtcagta aatgaagtga ctgaagtccc agatctttaa
    22441 gcatttgtgc tccaatatga tattctctta aatcaccttc aaagcctaat gcaagattgg
    22501 catcaagcgt atccatgcct tgatcttgta aatgataggc ttttaattta ttgataagtc
    22561 caattcctcg tccctcctgt cgcaagtaaa gtaagacacc cgaaccattc tcaacaatca
    22621 ttttcatagc tttatcgaat tgctgtccac aatcgcaacg taaggagcct aaaacatccc
    22681 ctgttaaaca ttcggagtgg acccgacata atacattggc ttcatcctct atgtttccca
    22741 taataagagc aagatgatgt tccccattta gtttatctat atagctaatt gctttgaaat
    22801 taccgtatct agtaggcata ttgacagttg aaactcgttc taccagctga tcatatactt
    22861 ttctatattc ttgtaattct ttgatggtaa ttagtggaat gttgtgtttc ttcgagaact
    22921 gaattaaatc atctgttctc atcattttgc catcatgatt cattatttca caacataggc
    22981 cacactcttt tagtccagct aattttaata aatcaacagt tgcttctgtg tgtccatttc
    23041 tttctagaac accacctttt tttgcaatta aaggaaacat gtgtcctggc ctgcgaaaat
    23101 cagagggtgt tatatcttca gctacacaca tacgtgcggt cagtcctctt tcctcggcag
    23161 aaatacctgt ggtcgtttct ttataatcaa ttgaaactgt aaaagcagtc ttatgattat
    23221 ctgtattgtt ttcaaccata ggtgaaagca ttaattgatt agctaaactt tcgctcatag
    23281 gcatacaaat taatcctttg gcataagtag ccataaaatt aacattttct gttgtagctg
    23341 cttgtgcaga acaaattaag tctccttcat tttctctatc cttgtcgtct ataacaagaa
    23401 caagtcgtcc cttctgcaat gcttctaatg cttcttgtat ttttcgatat tccattgact
    23461 gattatcctt tctgctaaaa tccattttga tataatagtt ccttagatat ttctgatttt
    23521 ggagagttat ccatcagttt ttgcacatat ttacctaaga tatcattttc aagatttact
    23581 gtactcccga cttgtttact cttaagaatg gtttgttcca aggtatgagg gataacagat
    23641 actgaaaagt ttactttgga gactttagcg acagtcagac taatgccgtc aattgtaata
    23701 gatccttttt caactattaa atctaaaatt tctttttgtg tgttgatttg ataccataca
    23761 gcattatcat ctttttttat tgacgagatt tttcctgtac catcaatgtg tcctgtaacg
    23821 acgtgacccc caagtcgacc gttgacagat aaggctcttt ctagattcac ctcacttcca
    23881 tgttttaata gagtaagagc tgttcgactc catgtttcat tcattacatc aactgtaaag
    23941 gattgatgat tgaaatgagt aactgtaaga cagataccat ttactgctat actatcgcct
    24001 aaatggatat ccgttaatat ttttgaggct ttaattgata gtttacaatt acgagagtct
    24061 ttctgtattc tttcaacttt tccgatttct tcaattattc ctgtgaacat ggataaatca
    24121 cttcactttc tatgagatag tcatttccta tttgagaaaa tgcataaggt ttcaatctaa
    24181 tagcgccatt tggcaaagaa ataccttcac ctccgacagg aaacttggca ctacctccaa
    24241 aaatttttgg tgcaatatat attttcagct catcaacaat ttgttgttcc aaagcactcc
    24301 aattcattag actgccccct tctagaacta ggctatcaat ctgcatgttt cctagatgtt
    24361 gcattaaact cgataagtct atatgattgc cttttttctt tatggaaagt atttcacagc
    24421 catgattttg atatagcttc attttatttt tgtcttcaga ggaagtggca atgtaagttt
    24481 taatatcatt tgctgttttt acgattttag aggtaagagg agttcgtaaa tgtgtatcgc
    24541 atatgatacg gataggattt ttcccttcct ccaatctaca tgtcagcaaa ggatcgtctt
    24601 gaataacagt attgactccc accataattg cactaacata gtgtcgtaac tgatgcacat
    24661 gctttcttgc ttcttcttca gtaatccatt tggattgatt tgttttagtg gctatttttc
    24721 catccattga cattgcatat ttcataaaaa catagggtac atgctgggta atatactttc
    24781 taaaactttt tattaagtta agacactcat tttctaaaat tccaacagta acttgaagat
    24841 tattttcctc aagtatcttt actccttttc cagatacaat aggattacag tctaggcttc
    24901 caatgactac tcttgtaata ccactatcga ttatagcatc tatacaggga ggtgttttcc
    24961 cgaagtgaca acagggttca agtgttacat aaagcgtcgc tccgacaggg gattttctac
    25021 agtttttaag agcatttctc tcagcatgtg ggccaccaaa aaactcatga taaccttgtc
    25081 cgatgatgtg attatctttt acaataactg cgccgaccat aggattggga ttgacgtaac
    25141 cagccccttt ttgtgccagt tttattgcta atttcatata ttttgaatcg ctcatctcac
    25201 tacctccaaa aaaaatatac cttgaatagg ggactactca aggcatacaa aagaaaactt
    25261 atacgattaa caaaaatact ctgaaatgac aagtaatcat ttcagagcac gcaaaaagca
    25321 caaatatact tttatcttct ttcatccaga ctatactgtc ggctttggaa tttcaccaaa
    25381 tcatgccttt cggctcgtgg gctataccac cggtagggaa ttgcaccctg ccctgaagat
    25441 agttattcaa ttacagatga ttatagtact taattttgaa tatgtcaaca gataaatacc
    25501 gattgttttt gatatactgt atttgtgata atcgattctc gctcctcgga taaagaaaat
    25561 atgatatact agataaacga aataagagag aaggaatact atgtacgcat atttaaaagg
    25621 aatcattacc aaaattactg ccaaatacat tgttcttgaa accaatggta ttggttatat
    25681 cctgcatgtg gccaatcctt atgcctattc aggtcaggtt aatcaggagg ctcagattta
    25741 tgtgcatcag gttgtgcgtg aggacgccca tttgctttat ggatttcgct cagaggatga
    25801 gaaaaagctc tttcttagtc tgatttcggt ctctgggatt ggtcctgtat cagctcttgc
    25861 tattatcgct gctgatgaca atgctggctt ggttcaagcc attgaaacca agaacatcac
    25921 ctacttgacc aagttcccta aaattggcaa gaaaacagcc cagcagatgg tgctggactt
    25981 ggaaggcaag gtagtagttg caggagatgg ccttcctgcc aaggtcgcag tgcaagcaag
    26041 tgttgaaaac caagaattgg aagaagctat ggaagccatg ttggctctgg gctacaaggc
    26101 aacagagctc aagaaaatca agaaattctt tgaaggaacg acagatacag ctgagaacta
    26161 tatcaagtcg gcccttaaaa tgttggtcaa ataggagcag agaatgacaa aacgttgttc
    26221 gtgggtcaag atgaccaacc cactctacat cgcctatcat gatgaggagt ggggccagcc
    26281 cctccatgat gaccaagcgt tgtttgagtt gttgtgtatg gaaacctatc aggcaggcct
    26341 gtcttgggaa acggtactca acaaacgcca agctttccga gaagcctttc atagctatca
    26401 aattcactca gtcgcagaga tgactgacac tgaattggaa gccatgctgg agaatccagc
    26461 tatcattcga aatagagcca agatttttgc tacacgcgct aacgcccaag cttttctaca
    26521 gttacaggca gagtacggct cttttgatgc ctatctttgg tcttttgttg aggggaaaac
    26581 tgtcgttaac gatgttcctg attatcgcca agccccagtt aaaacaccct tatctgagaa
    26641 attagccaaa gatctcaaaa aacgaggctt caagttcaca ggcccagtcg ccgtattgtc
    26701 ttttctacag gctgcagggc tagttgatga ccacgagaat gattgtgagt ggaaaggtct
    26761 taaatgatgt ctaacaaaaa taaggaaatt ctgatttttg cgattctcta tacagtcctc
    26821 tttgtgtttg atggcgttaa attgctggct tctttaatgc catctaccat tgcaaattat
    26881 cttgtttatg tagttttagc tttatatggc tccttcttgt tcaaggatag attgatccaa
    26941 taatggaagg agattagaaa gactaaaaga aaattcttct ttggagtctt aacaggatgg
    27001 ctctttctca ttctgatgac tgttgtcttt gaatttgtat cagagatgtt gaagcagttt
    27061 gtgggactag atggacaagg tctaaatcag tctaatattc aaagtacctt tcaagaacaa
    27121 ccactactga tagctgtttt tgcttgtgtc attggacctc tgatagaaga attatttttc
    27181 cgtcaggtct tattgcatta cttgcaggaa cggttgccag gtttactaag cattattctg
    27241 gtaggacttg tttttgctct gactcatatg cacagtttgg ctctatcaga gtggattggt
    27301 gcagttggtt acttaggtgg aggccttgcc ttttctatta tttatgtgaa agaaaaagaa
    27361 aatatctact atcccctact tgttcacatg ttaagcaaca gcctctcctt aatcatttta
    27421 gttatcagta tagtaaaatg aaataagaac aggacagtca aatcgatttc taacaatgct
    27481 ttagaagtag aggtgtacta ttctagtttc aatacactgt aacatgtgat gaaaatgcca
    27541 gtaatgatac cgagaaaaaa gctgagaaac ttttcccagc tttatttgtt atagtcaaag
    27601 cgaatgactt gttcctgtgc atctacatga gcatggaccc caaagggtac aattgctctt
    27661 ggagttgcgt ggccgacatt cagattatag acaatcggga tattgttgtc aatgatatcc
    27721 aatagtgcct ctttatagtc gtcatggaaa atttcatcca taggttttcc gaccaagagt
    27781 ccattgatga ccgcgaatat gccagtgtcc tttaaagtta gcaacatctt tttgaagtct
    27841 tctggcttag gctcttcttc gcttgtttcg agcaagagga ttttcccttc ccagtctgac
    27901 aagtcaggga aaagtttgta tttttggcag agttccgtgc tatctgcgta tcgagagttg
    27961 tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga ttttcccctc gaactgggca
    28021 cttccttgca acaagtcaaa acctgtattt gtatgactga cacgaggtgt tcccagggcc
    28081 gtgggactaa aatcagttcg ttcctcatac caaacgtcac tagggcggat ttctgaaatt
    28141 cttcccgtct caatcaattc tttaaagtag tgaaggctat aggctagcat ttctttgtct
    28201 aattcacaaa tgtctgctaa aaaggattga ccataaaaag tcttgattcc taatttatgc
    28261 aacatgaggt ggttcatggt tgtatccgag aagccaagaa aaattttttg tttgataacc
    28321 ttttggagtt ggtcattttc aaaaagataa ggtagcaagc gataggtatc gtctccaccg
    28381 atggcacata ggatcatgtc gatgctatca tcagaaaagg catgaatcaa atcctctgca
    28441 cgagcttcag gatggtcctt gataaagttt aatcctttta acgaatgggg caaaaagatg
    28501 ggattgagtc ccagatcctt gagacgttgg atacccaagt ccacttcgtg tttgacaaaa
    28561 tcctctccga taatgccact agataaacta acaataccaa tagtagaaac catatctcat
    28621 cctcctagaa atagattgag cctattttat cacaaaatat aagagaaagc tatgtgggat
    28681 ttcagaagaa tacttttaat actcttcgaa aatctcttca aaccacgtca gttttatctg
    28741 caacctcaaa gctgtgcttt gagcaacctg cagctagctt cctagtttgc tctttgattt
    28801 tcattgagta taactcaaaa aagtaagtga aaaagcaacc gcacctgcag ttgcttttat
    28861 cgttttctta ttcttgatag cgtgttggtc ctgcacttgc actacggata ttcaagcgtt
    28921 tcttgagata gaagcgaagg gctaggaggg ctgctccaat aatagctagt ggcaatggat
    28981 ccagtactgg gttaaggcta gctggtagga agcttgttgc aaagaagaca agcaaccaaa
    29041 ggaacataga agctaggata actagtacag atttccagaa aggtggacgt tgactgcgat
    29101 ccatatctgg tccatagtat tggtaaacaa agtagtacat caagtagaag gcaaatccac
    29161 caaccagtcc aactaataga agagtaatca atccatagcc gaaagcttga tctgccgcaa
    29221 agaaggttgt gagggcgctg acaagggcaa agaggctagt gatgaaaaga gctgagtcca
    29281 taatcatcag ttttggatca tcattttctt ttggatgctc tttttcgtac tgctctttga
    29341 cagtgaagct atgagcccaa tgagttggtg cgccgtatag ggaacgggca gttgtacctt
    29401 tagattgctc ctcaaggatg tggggaatga cttcctcaaa aatagtctgg atttcagcgt
    29461 ctgttttccc atctttgatg aattgttggg tagcaatgtg gacaaactct tggtttttct
    29521 tagttaattt ttgtagatca atttgagaca taggaactcc tcttagaacc attttttatg
    29581 gatgagatag agagtgagcg agacactcat agcaaaggcg ataaagacga ttaaccagaa
    29641 ggcatttggc tctccgttta gggggatttc attatcctta aagttcatcc cgtaggcaga
    29701 aaagaccatg gttgggatgg acatgacgat ggtcacaagg gccaaggttt tcatgatgtt
    29761 gttctggttg ttagaaatga tagaggcaaa ggtctctgtc atagaatgca agacgtttcc
    29821 ataaatatct gccatctcga tggcctgttg ggtttcaatc agggtgtctt caagcaggtc
    29881 ttcgtcctca aggtatttct tgatattgct ggttgaactg gtcaatttct taatcacgcg
    29941 ctcatttgtt ttgagggagg ccttgaaata gacgatagtt ttttccaatt ccatgagctc
    30001 aatcaattct tcattacgag ttgattgatg cagttgactt tcgatttgtt cactcttgcg
    30061 gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg cgataaagaa tttgaaagat
    30121 aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga cggttgataa agacatcaag
    30181 gacaggtagt ggttccaaac acgtagtgat aatggtttcc tcagtgatga taataccaag
    30241 cgggatggtt acgtagtagg tgcggttatt tctttcctcc gtgaccggca cgtctacgat
    30301 aatcagggta tactcgtctt caatggtaat acgagacatt tcttccgcat cgagcggtgc
    30361 tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt tcgagtgatt cattttgagt
    30421 cggattgacg agattgatcc aagtacccgg ttcaagcgta tcgatctctt taaattcagt
    30481 tgttgtagag agaaaaactt gtttcatatc ccttatcctt tctcattttt cagatttttt
    30541 cacactgtac tattatacta caaaatcggc cttttgggta atagaatctc actttttttg
    30601 gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa attgtcattc
    30661 atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga gacaagttgg
    30721 ttgtcgtgac tggcttgtca ggttcaggga agtccagtct ggcttttgat accctctatg
    30781 cggagggaca acgtcgctat gtagagagtt tgtccgccta cgctcgtcag ttcttgggaa
    30841 atatggaaaa accagatgta gatgccattg atggtctcag cccagctatt tccatcgacc
    30901 agaaaacgac tagtaaaaat cctcgctcga cggtgggaac gacgactgaa atcaatgact
    30961 atctgcgtct cctctacgca cgtgtgggga cgccttactg tatcaacgga catggagcta
    31021 tcaatgcttc ttctgtggag caaatcgttg ataaggtttt ggagttacct gaacgccagc
    31081 gcttgcagat cttggctcct gtcatccgca agaaaaaagg ccaacataag aatgttatcg
    31141 agaaggttca gaaagacgga tatgttcgtg tccgtgtgga tggggaagtc tatgatgtga
    31201 ccgaagtgcc agagttgtct aagagcaagc aacacaatat cgatgtcgtg gttgaccgta
    31261 ttgttatcaa ggagggcatt cgtagccgtc tctttgattc cattgaagct gcccttcgta
    31321 tcgcagaagg ttatgtgatt atcgacacca tggacgattc ggagttgctc ttctctgagc
    31381 attatgcctg tccagtttgt ggatttactg tcccagagtt agagcctcgt ctcttctctt
    31441 tcaatgctcc ctttggctct tgtagtgagt gtgacggctt ggggattaag ctggaggtgg
    31501 atactgattt ggtagtgcca gatgccagca aaacgctacg tgagggggct ttggcacctt
    31561 ggaatcctat ctcatctaac tactatccaa atatgctaga gcaggctatg acagcctttg
    31621 gagtggatat ggataagccc tttgaggact tgtcagaaga agataagaac ttgattctct
    31681 acggctcgga tggcaaagaa tttcattttc actatgagaa tgaatttggc ggtgtgcgcg
    31741 atattgacat tccttttgag ggagtcgtca ctaatatcaa gcgtcgttac catgagacta
    31801 acagtgatta cacgcgcact cagatgcgtc tctacatgaa tgagctgacc tgcggaacct
    31861 gtcaaggcta tcgtctcaat gaccaggcct tgtctgtccg tgtgggcggc cagcaagggc
    31921 cacatattgg agaaatctca gacctgtcta tcgctgacca cttggacttg gtgagccagt
    31981 taactttgtc tgaaaatgaa gccatcattg ctcgtcccat tctcaaggaa atcaaggatc
    32041 gtttgacctt ccttaataat gtgggtctta actatctaac cctgtcacgt tcagcaggaa
    32101 ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt tccaacctat
    32161 caggtgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg gacaatgatc
    32221 gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc gtggtggaac
    32281 acgacgaaga taccatgcgt gaggctgatt atctgattga cgttggtcct ggtgccggtg
    32341 tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc aacagcaagt
    32401 ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa gagcgccgtg
    32461 tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga gaacaacttg caaaatgtca
    32521 cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt tcagggaaat
    32581 cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac cgtaattcag
    32641 acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt ttgattgata
    32701 ttgaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat acaggagttt
    32761 ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga ggctacaaga
    32821 aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca ggtgacggga
    32881 ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa gtttgccacg
    32941 gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat atttcgcagg
    33001 tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg aaaattcaac
    33061 gcaaactcca gaccatcaag gatgtagggc taggctatgt gaccttggga cagccagcta
    33121 ccactctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc cacaaacgct
    33181 cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat acagaggaca
    33241 ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga tggcaataca gtcctcgtca
    33301 tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg ggacctgagg
    33361 gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta gctgccaacg
    33421 aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa acgcgtacaa
    33481 gcatttctag ctaaaatgca agaaaaagaa ctagatggta tcatcatcaa caatcttaaa
    33541 aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat cagccgtgac
    33601 cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga aaccagtggt
    33661 tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt taaggacatg
    33721 ggcttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca ccgtatgcag
    33781 gcagcttttg caggtttgaa cttgcttcca caaactcagt ttgtggaagg tcttcgtatg
    33841 attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc agaccaagct
    33901 ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg aaattgagat tgccaacttc
    33961 cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac gatcctagct
    34021 agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt ggagttggga
    34081 gaagccatta ccatggactt cggctgtctc tatgaccact atgtcagtga tatgacccgg
    34141 actatctatc tagggcatgt tagcgatgag caggcagaga tttacaatac ggttctaaaa
    34201 gctaaccaag ccttgattga ccaagctaag gcaggcttag gtttccgtga ctttgacaaa
    34261 atccctcgtg atattatcat tgaggcaggt tatggtgact actttactca cggcattggc
    34321 cacggtattg gtctggatat ccatgaggaa ccctacttta gtcagacttc tacagaaact
    34381 attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg caaatatggc
    34441 gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt gaccctagct
    34501 ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa atgacgaaaa
    34561 aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta taatagacta
    34621 aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat acagtctcaa
    34681 gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta agttataaag
    34741 aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt ctaaccaaaa
    34801 cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa gcccttggag
    34861 tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa acaccgagaa
    34921 ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac aaggaagacg
    34981 atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa gcacgtttgc
    35041 gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta ttttaatttc
    35101 aaaaagaaag aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt tcctttttgt
    35161 cctggttggt tgcggacaga aaaaagaaac tggaccagct acaaaaacag aaaaagatac
    35221 gcttcagtcg gcattgccag ttattgaaaa tgctgagaag aatacagttg taaccaagac
    35281 tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta cttacaaaga
    35341 caagactttt ttgagtctaa ctatccaaca aaaacgtcca gtctctgatg agttgaagac
    35401 ttatattgac caacatggag tggaggaaac tcaaaaagct cttcttgaag cggaggagaa
    35461 ggataagtct atcattgaag ctcgtaaatt ggcaggtttc aaacttgaaa caaaactatt
    35521 gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg atgtcaagaa
    35581 ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga aaaatgaacc
    35641 aagcaaatat atttcagata gattggcaaa tggcgcgaca gaacaataga aaatccaaat
    35701 aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac tattctaagg
    35761 aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt ggacgattcc
    35821 aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa cgataagggt
    35881 tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc ctacgttcct
    35941 cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat cgttgaggaa
    36001 ttggttcgct actacctcaa aggacaagga gtcgatctat aacctatgag aattatggga
    36061 ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg ttttacagct
    36121 caagggcttg aaatcatcca gataaatgaa gaacaaggcc aatttggttt tgaccgcgtt
    36181 aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc taaaaacatg
    36241 aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa gctagaagag
    36301 ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc tgctgagcgc
    36361 atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat tgataagtta
    36421 gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa aggagaggct
    36481 atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact agtagatgag
    36541 caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga agaatttggt
    36601 aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg acaagttgaa
    36661 atccaagctt actcattcat cgaaaacgaa gatggaacag aaggcgaatt gcaaccaatc
    36721 ccagaagact cagaagacga atggaacatg attgaagaag tcttcaatag ttttatggag
    36781 gagtaaaaat gttcagtgaa tatttttacc ccagttcctt taaataagag agaactggta
    36841 agtccggggg acgtttttag cccagctcct tgaagtaaga gagagctggt aagtccgggg
    36901 acgtttttag ccctgctttt agaaaaaaga aagagcaggc agtctgggag actgtatcag
    36961 cccaactccc agaaatgggg aagagttgga acatccagtg gatgttttta gcccagttcc
    37021 tttaaataag agagaactgg taagtccggg ggacgttttt agcctgacgc taaaaataaa
    37081 aacagtcagt aagttcgggg gatgttttag cccagctcct tgaaataaga tagagctggt
    37141 aagtctgaga aactgtatca gcccaactcc cagaaatggg gaagagttgg aacgtccagt
    37201 gaacattttt accccaactc ttagaaattg agaagagttg gaacatctag tggatgtttt
    37261 tagcccatat tcacattcat agtagctagt tattagctaa ccaggtaaga ggtcgggacg
    37321 aaaatcctgg ccttgttttt attagtaacc atactttaat gcgataattg attggacttt
    37381 tgtcaaggag atgtgtatgt ttgaagtaga agaatggctc catagtcgga ttggtttgaa
    37441 ttttcgatca ggtttgggcc gaatacagca agcggtggat ttgttaggaa atcctgagca
    37501 gtcttaccct attatccacg taacagggac taatggaaaa ggatctacca ttgcttttat
    37561 gagggaatta tttatggggc atggcaaaaa agttgcgacc tttacctccc ctcatatcgt
    37621 ctctatcaat gaccgaatct gcattaatgg gcaacctata gcagacgcag actttatccg
    37681 tttggctgat caggtcaagg agatggagaa aacgcttctg caaactcctg accagttgtc
    37741 cttttttgaa ttgctgacct tagttgcttt tctttatttt agggagcaag aggtggattt
    37801 ggttttatta gaagtgggaa ttggtggctt acttgacacg accaatgtgg taactggaga
    37861 gcttgctgtc atcacctcca ttgggcttga ccatcaagaa accttgggtg atagtctaga
    37921 agcaattgca gagcagaaag ctggtatttt caaggctggt aagaaggcag tgattgcgaa
    37981 attgcctcca gaagctaggc ttgtctgtca gaaaaaagcc gaatctttag ctgttaacct
    38041 ttatcaggca ggtcaagatt ttttaatgct gaatggtgat ttttcaagct ctttactaaa
    38101 tctttcacag ctgaacatag gcttagaagg agtctatcag caggagaatg cagccttggc
    38161 gttgcaaact tttcttcttt ttatgggaga aggaaaggaa gctgttgatg aacaggctgt
    38221 aagaaaggcc ttggaacaga cccattgggc tggtcgcttg gagcgtattc gcccacagat
    38281 ttacttggat ggtgctcata acctccctgc cttgactcgc ttggttgagt ttatcaaaga
    38341 aaaagagcag gaaggttatc gacctcaaat cctctttgga tccttgaaac gtaaggatta
    38401 tcaagggatg ttgggttatc tgactgaaaa tttacctcaa gtggaactca aaatgactgg
    38461 ctttgactat caagggtctt tggacgagac agatgtaaca ggttaccatg taattccctc
    38521 ttaccgagaa tttatcagca ttttcgaaga aagggcagac gctcaagact tgctgttcgt
    38581 tacagggtct ctctatttta tctcagaagt acggggctac ctgctggacc gtgagcagat
    38641 aaattgaccc ccttgtttga acttgttata ctaggggaat tgctggttag agaaaatttc
    38701 tctaaattgg tagcagaaag gaaattcatc atgaaattaa aaagattcac actttctctt
    38761 gcttctctag caagttttag tctcttagta gcttgttcac aaagagctca acaggttcaa
    38821 cagcctgctc aacaacctgc tcaacagaat accaatactg caaatgcagg aggtaaccaa
    38881 aatcaagcgg ctccagtaca aaaccaacct gttgctcaac cgaccgatat tgatgggact
    38941 tatactggtc aggatgacgg agaccgtatc actttagtgg taactggaac gactggtaca
    39001 tggactgagc tcgaatctga cggggatcag aaagtcaaac aggttacatt tgattcagca
    39061 aatcaacgca tgattattgg cgatgatgtc aaaatttaca ctgtaaacgg taatcaaatc
    39121 gtcgtagatg atatggatag agacccatcg gaccaaatcg ttttaactaa ataagactat
    39181 gcaagtagaa agggctggat ttttcagcct ttttactttt acctagaaaa taatcataaa
    39241 tacttgcctt ctaccgaata cctgcgttat actagtatca attacttgtt tttagcattc
    39301 aaactatcaa ggaggggata tgaaatatag gaaatttcaa ttattgatgt ccaagtatgg
    39361 ctttagtctt tcgattatgc tacttgaact ttgtcttgtt tttggtctct ttctttattt
    39421 aggacgcatg gctcccattt tatggattac tgtcctcatt ctactgagta tcatcacaat
    39481 catttcgata gtcaaccgta atacgactcc tgagaataag gtaacctggt tgttagtagc
    39541 ctttgtgcca gtatttggtc ccttgctcta tctgatgttt ggtgaaaggc gattgtccaa
    39601 aaaagaaatc aaacaactga agaagctagg ctctatgcat ttccaagaag caaatagcca
    39661 gctactaaaa gagaaattaa aagaaagtga caaggcagct tatggagtca tcaagtcctt
    39721 attgagtatg gataccaatg ctgacatcta tgatcaaact gcctctacat tttttcctaa
    39781 cggagaagct atgtggaaaa agatggtaga agatcttaaa aaggctgaga aatttatttt
    39841 cttggaatat tacattatag aagaaggttt gatgtggaat cgcatactag atatactaga
    39901 gcaaaaggta gctcagggtg tagaggttaa gatgctctat gatgatatcg gctgtatggc
    39961 tactttaaca ggagattatg cacatcgact tcgtcagctg ggcatcgagg cccataaatt
    40021 caataaagtt attcctcgtc tgacagtggc ttataataac agagatcata gaaaaatatt
    40081 gattgttgat ggtcagatag cctatactgg tggggtcaat ctggcagatg agtacattaa
    40141 ccacgtcgag agatttggtt attggaagga tagtggaatt cgcttagacg gactagcagt
    40201 aaaagccctg acacgcttat ttttgaccac ttggtacatt aatcgaggag aaattagtga
    40261 ttttgatcaa tatcatttag aaaatcattc tatcccgagt gacggtttaa ccattccata
    40321 cggaagtgga cccaagccaa tttttcgagc gcaggtaggg aaaaaagttt atcagagttt
    40381 aatcaatcaa gcaacagaat cggtctatat tacgacacct tatttgatta tagattatga
    40441 tttaacagag acaatcaaaa atgcagctat gagaggggtc gatgttcgaa ttatcacccc
    40501 ttacatacca gataagaagt tcattcagtt agtcacgaga ggagcttatc ccgaccttct
    40561 ttctgctggt gttcggattt atgagtatag tccaggtttt attcatagta agcagatgtt
    40621 ggtagacgaa gattttgcgg tggtggggac aatcaatctc gactaccgga gcttggtaca
    40681 ccattatgaa aatgcagtct tactctataa aactccttct ataagggaaa tcgcccgaga
    40741 ttttcgaaat atatttgcag attctcagga agtctatcct cattctatca aaacgagctg
    40801 gtatcaaaag cttgtaaaag aaatcgccca gctattcgcc cctatcttat aagaaatcta
    40861 gaacttagga tacaaaccag acctattttt cttgtctttt acgaatagaa agaaagagga
    40921 ggggaattca tgctaactaa ggaagaagtg aatgatatga ttgagttcaa acagacacat
    40981 ttacaccgct ttcgggaaat tgaaaccttt gtgaaactat gcaaaaaatc actcaaacag
    41041 ccatcgcaag ctgacaatcc taggactttt tgatatacta agacagataa attgaacagg
    41101 agaaacgata tgagtgtgta tggtagagta gaagaagttc ataaggagaa tcgtgaacct
    41161 ctagaatacc aaatcgaaca agaatcgcat catcgtgaat caagtcgtct tcctttggtg
    41221 aaaattttac tatggagtac gcttgtaacg gggataactc taggagtacc gctattactc
    41281 gacttaatga gtgcacaaga agtgcaggat ttttatgcag gttgggcgct tcatcagaca
    41341 gggaagattt acagcgacta ttatggaagt caaggtttgc tttattattt gctgacttac
    41401 gtgagtcagg gcggattttt ctttgccatc tttgagtggt tagccttggt agcaggagga
    41461 tttttccttt ttagatcagc ggacaccttg acagagcaag gagaccaagc tggacatctg
    41521 gtgactattt tttacatgct agttacaggt cttgcttttg gtggaggcta tgcgactctt
    41581 ttagcgcttc ctttcttatt cgcagccttt agtttagttg cggcttacct aagcaatcca
    41641 agccatgata agggatttgt acggattggg ctagctttgg caggcggatt tttctttgct
    41701 cccttatcat cgctcctgtt tattgctgta gtgagtttag gcttgttggt ctttaacctt
    41761 gggcatagac gctttgcgca tgggttttat cagtttcttg cagtggcttt aggtttttca
    41821 cttgtctttt atccaactgc ctactatagt gctgcaacag gaagttttgg ggatgcgatt
    41881 agtggtattc gttatcctat tgacagtatt cgctttgatt ttacttctaa aattttagag
    41941 aatatgtttt tttatggctt gttgtccctt ggtttgggat ttgtggtttg tatcttttta
    42001 ggtctctttc aatccaaacc ctttaaacta tacgtcattt cggttcctgc aagtcttgtg
    42061 gtaattttag gtttgatttt acttttcttt tcacaagagc ctctgcacgc ttcttatttg
    42121 atggtcgtct tccctgtttt cctactttta ttggtaacca atattaagag tcaacagagg
    42181 gggcgtagtg ctagaagaag cctaagagaa acgccagtta gcctatggag tcgtttcttc
    42241 aaaggaaatc tatatctgct agtttttggg tttgtctatc ttttgtctgt tccttttttg
    42301 atgaagtttg tcctttatcc agtaccttat caagaacgta atcgtcttgc tgatttggta
    42361 aaagaggaga caaatacgga agatgctatc tatgcatggg atgatactgc gactctttat
    42421 cgtaagagtg agcgcttgtc gccatcggcg attttgtccc cgttgcacta tacagcaact
    42481 gaggaaaatc gtaataagtt acttaatgac ttgaaagaaa aacaacctaa ggtgattgtg
    42541 gtaaatgaca aggtggtagt ctggtctgaa gtggaaacac ttttaaaaga aaattaccaa
    42601 caagtaaaga ctgattactc agagtttaaa gtctataaaa ttaaataacc aaatcaatat
    42661 cttgtgtatt tttaaaaatt ttaggatttt taacacaaga tattgatttt tctttttaga
    42721 gtggtataat actttttaga aagaacattt tagaaaagag catgcgtatg attgcactag
    42781 aagaaaaaat tacaattttg ccaactctct tcgtcgagaa acgagatggg agacgtgttg
    42841 tatttgatgt ggacaagatt gacaaggctc tccacaaggc ggctgacaag gttatggatg
    42901 tgacacccct ggttgaaaaa cgcctcaatg atctgactga gcgaattatt acagaaattc
    42961 atagtcgctt tccacaggga attaagattt acgaaattca aaatatcgta gaacatgaac
    43021 tccttgaagc caaagaatat gcgctggctg aggagtatat tacttatcgg acacagaggg
    43081 attttgagcg ctcaaaagcg acggatatca actttagtat tcataaactt ctcaacaaag
    43141 accagacagt tgtcaatgaa aatgctaata aagacagtga tgtctttaac actcagcgtg
    43201 atttgacagc agggattgtt gggaaatcaa tcggactgca aatgcttcct aagcacgtag
    43261 ccaatgccca ccaaaagggg gatatccact atcacgattt ggactacagt ccctataccc
    43321 ctatgaccaa ctgctgtttg attgatttta agggtatgtt ggaaaatggt tttaagattg
    43381 gaaatgcaga ggtagagagt cccaagtcta tccagactgc gacagcacag atttctcaaa
    43441 tcattgccaa cgttgcttct agccagtacg gtggctgttc agctgaccgt atcgatgaaa
    43501 ttttggcgcc ttatgcagag aagaactatc aaaaacatct caaagatgca gaagagtggg
    43561 tattgcctga aaaacgggaa gattacgctt ggaagaaaac gcaaaaggac atctacgatg
    43621 ccatgcaatc tcttgagtat gaaatcaata ctctcttcac ttcaaatgga caaacacctt
    43681 ttacttcgtt aggttttggt ctgggaacca gtcgttttga acgagaaatt caaaaagcta
    43741 ttttaaacat tcgcatcaag ggtcttggtt cagaacaccg tacggctatc tttcctaaac
    43801 ttatctttac gcttaaaaga ggcctcaact tagaggaagg aactcccaac tatgacatca
    43861 agcagttggc tctagagtgt gcaaccaagc ggatgtatcc agacgtcttg tcttatgata
    43921 agattgttga tttgacaggt tctttcaaag ttcctatggg ctgccgttct ttccttcaag
    43981 ggtggaagga tgaaaatggt gtagaagtca attcaggtcg catgaatctg ggtgttgtga
    44041 cggttaatct gcctcgtatt gctcttgagt ctgaaggtga tatgaataag ttctgggaaa
    44101 tcttcaacga gcgaatgaat atcgcagaag atgctcttgt ttaccgtgtc gaacgcacta
    44161 aagaggcgac accagcgaat gctcctattc tttatcagta cggtgctttt ggccatcgtc
    44221 taggtaaaga agaaagtgtt gaccagctct ttaagaatcg tcgtgcgacc gtttcgctgg
    44281 gctatatcgg cttgtatgaa gtagcgacag ttttctttgg taacagctgg gaaagtaatc
    44341 cagatgctaa ggaattcacg ctagacatca ttcacgatat gaaacgccgt gtagaagagt
    44401 ggtcagacca atatggctac catttctcta tctactcaac accatccgaa agtctgacag
    44461 accgtttctg ccgactagat atagacaagt ttggctctat tcctgatatc acagacaagg
    44521 aatactacac caactctttc cactacgatg ttcgtaaaaa tccaacaccg tttgaaaaat
    44581 tggactttga gaaagtctat ccagaagcag gtgcgtcagg tggtttcatc cattattgtg
    44641 agtatccagt ccttcagcaa aatccaaagg ccttggaagc tgtctgggat tatgcttatg
    44701 accgtgtagg ctatctaggc accaatactc cgattgaccg ttgctacaag tgtgactttg
    44761 aaggggattt tgaaccaact gagagagggt ttgcttgtcc aaactgtggc aatagcgatc
    44821 ctaaaacagt agacgttgtt aaacggactt gtggctatct tggcaatcct caagcgagac
    44881 caatggttaa cgggcgtcac aaggaaatcg ctgcgcgtgt caaacatatg aatggttcaa
    44941 cgattaaaat agctgggcat caagtaacaa attagaaaga aatgaaatgg gaaaatatca
    45001 actagacgat aaggggcgcg cacaagtgac ccgttatcac gagaagcact ctaaaggtgg
    45061 agctggtaag aaagaacgct tgcttagctt cagagaacaa tttttaaaca agaacaagaa
    45121 aaaataaaag tgagagccag ctctcgcttt tctcatagtg ggaggtaggg atggaattac
    45181 gcagaccaag attagcggat aagaaagctg ttttagatat gatgacagag tttgaaaaga
    45241 gccaatcagc ccatgatgga ggattttggg atacagagaa ttttgtgtat gaagagtggt
    45301 tggaaagcaa tcaggaacag gaaatgggga ttaatctgcc tgaaggatgg gttcctgcaa
    45361 ttcagttagt ggctttttct gagaaaggtc aagcagttgg atttcttaat ctccggttgc
    45421 gcctcagtaa ctttttacta gaagaaggtg ggcacattgg ctactccatc cgtccatctg
    45481 aaagaggcaa gggttatgca aaagagactc tccgtcaggg cttgcaagtt gctaaggaaa
    45541 agaacatcaa gaaagctctg gtgacctgta gcgtgaataa tcctgctagc agagcagtca
    45601 ttctagcaaa tggtggaata tttgaggatg ctcacaatgg agtcgagcgt tattggatag
    45661 aggtagcgaa tgaataatcc aaaaccacaa gaatggaaaa gcgaggaact tagtcaaggt
    45721 cgtatcattg actacaaggc ctttaacttt gtggacggcg aaggcgtgcg taactctctc
    45781 tatgtatcag gctgtatgtt tcactgcgag ggatgttata atgttgcgac ttggtctttt
    45841 aatgctggca ttccctatac agcagaatta gaagagcaga tcatggcaga tcttgctcag
    45901 ccctatgttc aaggtttgac tttgttggga ggggagcctt ttcttaatac tgggattctc
    45961 ttgccacttg ttaagcggat tcggaaggaa ttgccagaca aggacatctg gtcctggacc
    46021 ggctacactt gggaagaaat gatgttggaa actccagata aactggaatt cttgtcactg
    46081 attgacattc ttgtcgatgg aagatatgat cgaactaaga gaaatcttat gctccagttt
    46141 cgaggttcat ctaaccaacg aattatcgat gtgcaaaaat cgctcaaaag tgggcaagta
    46201 gtgatttggg acaagctcaa tgacggaaaa gaaagctatg aacaggtgaa gagagaatga
    46261 agaaaaaaga cttagtagac caactagtct cagagatcga gacggggaaa gtcaggacac
    46321 tgggaatata cggtcatgga gcttcaggta aatcaacctt tgcacaggaa ttgtaccaag
    46381 ctttagattc tactacagta aatttgctag aaacagatcc ctatatcacc tccggacgct
    46441 atttggtagt acccaaggac gcgccgaatc aaaaggtgac agccagtctg ccagtggcgc
    46501 atgaactgga gagtttgcag agagatatcc ttgccttgca ggcgggtatg gatgtcttga
    46561 caattgaaga accttggaag gctagtgagg tcttgtctgg agccaaacca attttgattg
    46621 tcgaagggat gtctgttggt tttctaccca aggaactctt tgaaaaaacc atctgtttct
    46681 acacggatga ggagaccgaa ttaaagcgac gccttgctag agatacgact gtgagaaatc
    46741 gcgatgcatc ctttatattg gctagccatc agatgagacg ggagcagtat ctgcgatact
    46801 ataaagaaac tgagtctaag gcggatatct tagtggacca atcagaagat aaatttgatg
    46861 tcaagaggac ttaacttatg tatagaagaa atatagaaga aaatccctaa ttttagaaag
    46921 aaaaagtagg aaaacagttt catcccaaaa aaacgaaaaa acctaacaaa tcccttgcaa
    46981 tcgcagggga tttgtgttat tctattatgg tgctgtaaat tacagcctta gttttgatgc
    47041 aagaggttgc gacacgctcg gttgcattgc cacgcaacac cgcgtcggtt ttcttgtgga
    47101 gctagcctat tatcttaaat agacgaaaag gagaaaaaga tggcaaacaa aaaaatccgt
    47161 atccgtttga aagcttacga acaccgtacg cttgacacag cggctgcaaa aatcgtagaa
    47221 tcagctactc gtacaggtgc acaagttgcg ggtccaatcc cacttccaac tgaacgtagc
    47281 ctctacacaa tcattcgtgc gactcacaaa tacaaagact ctcgcgaaca atttgaaatg
    47341 cgtacacaca aacgtttgat cgatatcgtt aacccaactc aaaaaacagt tgatgccttg
    47401 atgaaattgg atcttccaag tggtgtaaac gtagaaatca aactttaatc taaaatataa
    47461 aagagcagag gctggtgttt caatctaatt gaacacgggc tagactcggt gtgaaaaaga
    47521 taaacttcct attgtccgct agacactgcg ttagtttcct attttcactt tgagtttgac
    47581 gccctttgta tcttagactt gagcataaaa aacgctcgtt aaaaactttt tgaataaaaa
    47641 atatagaaaa ggaactattt tctcatgaca aaaggaatct tagggaaaaa agtgggaatg
    47701 actcaaatct tcactgaagc tggcgaattg atccctgtaa cagttattga agcaactcca
    47761 aacgttgttc ttcaagttaa aactgttgaa acagacggat acaacgctat ccaagttggt
    47821 ttcgatgaca aacgcgaagt attgagcaac aaacctgcta aaggacatgt agcgaaagct
    47881 aacacggctc ctaagcgctt cattcgtgaa ttcaaaaacg ttgaaggctt ggaagttggt
    47941 gctgaaatta cagttgaaac attcgcagct ggagatgttg ttgatgtaac tggtacttct
    48001 aaaggtaaag gtttccaagg tgttatcaag cgccacggac aatcacgtgg accgatggct
    48061 cacggttctc gttaccaccg tcgtccaggt tctatgggac ctgttgcacc taaccgcgta
    48121 ttcaaaggta aaaaccttgc aggacgtatg ggtggtgacc gcgtaacaat tcaaaatctt
    48181 gaagttgtac aagttgttcc agaaaagaac gttatcctta tcaaaggtaa cgtaccaggt
    48241 gctaagaaat ctcttatcac tatcaaatca gcagttaaag ctggtaaata ataaagaaag
    48301 gggaaatcag tcacaatggc aaacgtaaca ttatttgacc aaactggtaa agaagctggc
    48361 caagttgttc ttaacgatgc agtatttggt atcgaaccaa atgaatcagt tgtgtttgat
    48421 gtaatcatca gccaacgcgc aagccttcgt caaggaacac acgctgttaa aaaccgctct
    48481 gcagtatcag gtggtggacg caaaccgtgg cgtcaaaaag gaactggacg tgctcgtcaa
    48541 ggttctatcc gctcaccaca atggcgtggt ggtggtgttg tcttcggacc aactccacgt
    48601 tcatacggct acaaacttcc acaaaaagtt cgtcgcctag ctcttaaatc agtttactct
    48661 gaaaaagttg ctgaaaacaa attcgtagct gtagacgctc tttcatttac agctccaaaa
    48721 actgctgaat ttgcaaaagt tcttgcagca ttgagcatcg attctaaagt tcttgttatc
    48781 cttgaagaag gaaatgaatt cgcagctctt tcagctcgta accttccaaa cgtgaaagtt
    48841 gcaactgcta caactgcaag tgttcttgac atcgcaaata gcgacaaact tcttgtcaca
    48901 caagcagcta tctctaaaat cgaggaggtt cttgcataat gaatttgtat gatgttatca
    48961 aaaaacctgt catcactgaa agctcaatgg ctcaacttga agcagggaaa tatgtatttg
    49021 aagttgacac tcgtgcacac aaacttttga tcaagcaagc tgttgaagct gctttcgaag
    49081 gtgttaaagt tgccaatgtt aacacaatca acgtaaaacc aaaagctaaa cgtgttggac
    49141 gttacactgg ttttactaac aaaactaaaa aagctatcat cacacttaca gctgattcta
    49201 aagcaatcga gttgtttgct gctgaagctg aataatctaa ggaggaaata tcgtgggaat
    49261 tcgtgtttat aaaccaacaa caaacggtcg ccgtaatatg acttctttgg atttcgctga
    49321 aatcacaaca agcactcctg aaaaatcatt gcttgttgca ttgaagagca aggctggtcg
    49381 taacaacaac ggtcgtatca cagttcgtca ccaaggtggt ggacacaaac gtttctaccg
    49441 tttggttgac ttcaaacgta ataaagacaa cgttgaagca gttgttaaaa caatcgagta
    49501 cgatccaaac cgttctgcaa acatcgctct tgtacactac actgacggtg tgaaagcata
    49561 catcatcgct ccaaaaggtc ttgaagtagg tcaacgtatc gtttcaggtc cagaagcaga
    49621 tatcaaagtc ggaaacgctc ttccacttgc taacatccca gttggtactt tgattcacaa
    49681 catcgagttg aaaccaggtc gtggtggtga attggtacgt gctgctggtg catctgctca
    49741 agtattgggt tctgaaggta aatacgttct tgttcgtctt caatcaggtg aagttcgtat
    49801 gattcttgga acttgccgtg ctacagttgg tgttgtcgga aacgaacaac atggacttgt
    49861 aaaccttggt aaagcaggac gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc
    49921 tgtaatgaac cctaacgatc acccacacgg tggtggtgaa ggtaaagcac cagttggtcg
    49981 taaagcacca tctactccat ggggcaaacc tgctcttggt cttaaaactc gtaacaagaa
    50041 agcgaaatct gacaaactta tcgttcgtcg tcgcaacgag aaataatatt aaactagtcg
    50101 cttaagcaac tagtaaatcc gccagctcgg tagcgctcca taggagtgca agccgctgtg
    50161 gtacaacatt taaaggagaa aatataaaaa tgggacgcag tcttaaaaaa ggacctttcg
    50221 tcgatgagca tttgatgaaa aaagttgaag ctcaagctaa cgacgaaaag aaaaaagtta
    50281 ttaaaacttg gtcacgtcga tcaacgatct tcccaagttt cattggttac actattgcag
    50341 tttatgacgg acgtaaacac gtacctgttt acatccaaga agacatggta ggccacaaac
    50401 ttggtgaatt tgcaccaact cgtacttaca aaggtcacgc tgcagacgac aagaaaacac
    50461 gtagaaaata aggagaacat aaatggcaga aattacttca gctaaagcaa tggctcgtac
    50521 agtacgtgtt tcacctcgta aatcacgtct tgttcttgat aacatccgtg gtaaaagcgt
    50581 agccgatgca atcgcaatct tgacattcac tccaaacaaa gctgctgaaa tcatcttgaa
    50641 agttttgaac tcagctgtag ctaacgctga aaacaacttt ggtttggata aagctaactt
    50701 ggtagtatct gaagcattcg caaacgaagg accaactatg aaacgtttcc gtccacgtgc
    50761 gaaaggttca gcttcaccaa tcaacaaacg tacagctcac atcactgtag ctgttgcaga
    50821 aaaataagga ggtaaaatcg tgggtcaaaa agtacatcca attggtatgc gtgtcggcat
    50881 catccgtgat tgggatgcca aatggtatgc tgaaaaagaa tacgcggatt accttcatga
    50941 agatcttgca atccgtaaat tcgttcaaaa agaacttgct gacgcagcag tttcaactat
    51001 tgaaatcgaa cgcgcagtaa acaaagttaa cgtttcactt cacactgcta aaccaggtat
    51061 ggttatcggt aaaggtggtg ctaacgttga tgcactccgt gcaaaactta acaaattgac
    51121 tggaaaacaa gtacacatca acatcatcga aatcaaacaa cctgatttgg atgctcacct
    51181 tgtaggtgaa ggaattgctc gtcaattgga gcaacgtgtt gctttccgtc gtgcacaaaa
    51241 acaagcaatc caacgtgcaa tgcgtgctgg agctaaagga atcaaaactc aagtatcagg
    51301 tcgtttgaac ggtgcagata tcgcccgtgc tgaaggatac tctgaaggaa ctgttccgct
    51361 tcacacactt cgtgcagata tcgattacgc ttgggaagaa gcagatacta catacggtaa
    51421 acttggtgtt aaagtatgga tctaccgtgg tgaagttctt ccagctcgta aaaacactaa
    51481 aggaggtaaa taaccaatgt tagtacctaa acgtgttaaa caccgtcgtg agttccgtgg
    51541 aaaaatgcgc ggtgaagcaa aaggtggaaa agaagtagca ttcggtgaat acggtcttca
    51601 agctacaact agccactgga tcactaaccg ccaaatcgaa gctgctcgta tcgccatgac
    51661 tcgttacatg aaacgtggtg gtaaagtttg gattaaaatc ttcccacaca aatcatacac
    51721 tgctaaagct atcggtgtgc gtatgggatc tggtaaaggg gcacctgaag gttgggtagc
    51781 accagttaaa cgtggtaaag tgatgttcga aatcgctggt gtatctgaag agattgcacg
    51841 tgaagcgctt cgacttgcta gccacaaatt gccagttaaa tgtaaattcg taaaacgtga
    51901 agcagaataa ggagaaggca tgaaacttaa tgaagtaaaa gaatttgtta aagaacttcg
    51961 tggtctttct caagaagaac tcgcgaagcg cgaaaacgaa ttgaaaaaag aattgtttga
    52021 acttcgtttc caagctgcta ctggtcaatt ggaacaaaca gctcgcttga aagaagttaa
    52081 aaaacaaatc gctcgtatca aaacagttca atctgaagcg aaataataga ctagggaagg
    52141 agaaatttca atggaacgca ataatcgtaa agttcttgtt ggacgtgttg tatctgacaa
    52201 aatggacaag acaatcacag ttgtagttga aacaaaacgt aaccacccag tctatggtaa
    52261 acgtattaac tactctaaaa aatacaaagc tcatgatgaa aacaatgttg ccaaagaagg
    52321 cgatatcgta cgtatcatgg aaactcgccc gctttcagct acaaaacgtt tccgtcttgt
    52381 agaagttgtt gaagaagcgg tcatcatcta atcaaacctg aaaggagaaa actgaaatga
    52441 ttcaaacaga aactcgtttg aaagtcgcag acaacagcgg tgctcgcgaa atcttgacta
    52501 tcaaagttct tggtggttca ggacgtaaat ttgcaaacat cggtgatgtt atcgtggcat
    52561 ctgtaaaaca agctactcct ggtggtgcgg ttaaaaaagg tgacgttgtt aaagcagtta
    52621 tcgttcgtac taaatcaggt gctcgtcgtg ctgatggttc atacatcaaa tttgacgaaa
    52681 acgcagcagt tatcatccgt gaagacaaaa ctcctcgcgg aacacgtatc tttggcccag
    52741 ttgcacgtga attgcgtgaa ggtggcttca tgaagatcgt gtcacttgct ccagaagtac
    52801 tttaattttt aggaacaaac tagtccccta gcttcaagct agggtgccct tatgggcgta
    52861 agaaaaatca aggagaaacc taatgtttgt aaaaaaaggc gacaaagttc gcgtaatcgc
    52921 tggtaaagat aagggaacag aagctgttgt ccttactgcc cttccaaaag taaacaaagt
    52981 tatcgttgaa ggtgttaaca ttgttaagaa acaccaacgt ccaactaacg agcttcctca
    53041 aggtggtatc atcgagaaag aagcagctat ccacgtatca aacgttcaag ttttggacaa
    53101 aaatggtgta gctggtcgtg ttggttacaa atttgtagac ggtaaaaaag ttcgctacaa
    53161 caaaaaatca ggcgaagtgc ttgattaatc acgaaggaaa ggagaagtat aatggcaaat
    53221 cgtttaaaag aaaaatatct taatgaagta gttcctgctt tgacagaaca attcaactac
    53281 tcatcagtga tggctgtgcc taaagtagat aagattgttt tgaacatggg tgttggtgaa
    53341 gctgtatcaa acgctaaaag ccttgaaaaa gctgctgaag aattggcact tatctcaggt
    53401 caaaaaccac ttatcactaa agctaaaaaa tcaatcgccg gcttccgtct tcgtgaaggt
    53461 gttgcgatcg gtgcaaaagt tacccttcgt ggtgaacgta tgtacgaatt cttggataaa
    53521 ttggtatcag tttcacttcc acgtgtacgt gactttcacg gtgttccaac aaaatcattt
    53581 gatggacgcg ggaactacac acttggtgtg aaagaacaat taatcttccc agaaatcaac
    53641 ttcgatgacg ttgacaaaac tcgtggtctt gacatcgtta tcgtaacaac tgctaacact
    53701 gacgaagagt cacgtgcatt gcttacaggc cttggaatgc cttttgcaaa ataatatagg
    53761 aggtaaatct aatggctaaa aaatcaatgg tagctagaga ggctaaacgc caaaaaattg
    53821 ttgaccgtta tgctgaaaaa cgtgctgcat taaaggcggc aggggactac gaaggtttat
    53881 ctaaattacc tcgcaacgcc tcaccgactc gtttacataa tcgttgtaga gttacggggc
    53941 gcccacattc agtttaccgc aaatttggtc tgagtcgtat cgcttttcgc gaacttgcgc
    54001 ataaaggtca aattcctggt gtaacaaaag catcttggta atttaagata tcaagggtgt
    54061 caaaactcca agtaaaaata ggaaacttga cgaagaaact aaagtttcta ggaaagttta
    54121 tctttttcac acagagttta gcccgagcta cagctttggc aaaaaagacc aatttgcttt
    54181 ggagcattgc ttctgcatta aattgtctat ttttgctcgt gctgttacgc tctttgtatc
    54241 atgtattaac tagcaagtgc aacttgcaaa ctactagtaa gaggagaaaa acaaaatggt
    54301 tatgactgac ccaatcgcag acttcctaac tcgtattcgt aatgctaacc aagctaaaca
    54361 cgaagtactt gaagtacctg catcaaacat caaaaaaggg attgctgaaa tccttaaacg
    54421 cgaaggtttt gtaaaaaacg ttgaaatcat cgaagatgac aaacaaggcg tcatccgtgt
    54481 atttcttaaa tacggaccaa atggtgaaaa agttatcact aacttgaaac gtgtttctaa
    54541 accaggactt cgtgtctaca aaaaacgtga agaccttcca aaagttctta acggacttgg
    54601 aattgccatc ctttcaactt ctgaaggttt gcttactgat aaagaagcac gccaaaagaa
    54661 tgttggtggt gaggttatcg cttacgtttg gtaaaatcaa gatacaaagc tcgtaaagaa
    54721 caaagcaaaa ttaggaagtt ggagaagttt gtttacaaac aagccaactt atctattttg
    54781 cacatttctt agagcgtgtt cagttcagct cttgaactaa ataagtatct gaaccccgtg
    54841 aaaactggcc gttctggcct gacaatttaa caggagaaaa taaacatgtc acgtattggt
    54901 aataaagtta tcgtgttgcc tgctggtgtt gaactcgcta acaatgacaa cgttgtaact
    54961 gtaaaaggac ctaaaggaga acttactcgt gagttctcaa aagatattga aatccgtgtg
    55021 gaaggtactg aaataactct tcaccgtcca aacgattcaa aagaaatgaa aactatccac
    55081 ggaactactc gtgccctttt gaacaacatg gttgttggtg tatcagaagg attcaagaaa
    55141 gaacttgaaa tgcgtggggt tggttaccgt gcacagcttc aaggatctaa acttgttttg
    55201 gctgttggta aatctcatcc agacgaagtt gaagctccag aaggaattac ttttgaactt
    55261 ccaaacccaa caacaatcgt tgttagcgga atttcaaaag aagtagttgg tcaaacagct
    55321 gcttacgtac gtagccttcg ttcaccagaa ccatataaag gtaaaggtat ccgttacgtt
    55381 ggtgaattcg ttcgccgtaa agaaggtaaa acaggtaaat aatgttgagt ggttgatcat
    55441 caaccaccaa cctattttcc aactttgtgc atagcacacg atttaaaact aaagaggtga
    55501 aaactgtgat ttcaaaacca gataaaaaca aactccgcca aaaacgccac cgtcgcgttc
    55561 gcggaaaact ctctggaact gctgatcgcc cacgtttgaa cgtattccgt tctaatacag
    55621 gcatctacgc tcaagtgatt gatgacgtag cgggtgtaac gctcgcaagt gcttcaactc
    55681 ttgataaaga agtttcaaaa ggaactaaaa ctgaacaagc cgttgctgtc ggtaaactcg
    55741 ttgcagaacg tgcaaacgct aaaggtattt cagaagtggt gttcgaccgc ggtggatatc
    55801 tatatcacgg acgtgtgaaa gctttggctg atgcagctcg tgaaaacgga ttgaaattct
    55861 aataggagga cactagaaaa tggcatttaa agacaatgca gttgaattag aagaacgcgt
    55921 agttgctgtc aaccgtgtta caaaagttgt taaaggtgga cgtcgtcttc gtttcgcagc
    55981 tcttgttgtt gttggtgacc acaatggtcg cgtaggattt ggtactggta aagctcaaga
    56041 agttccagaa gcaatccgta aagcagtaga tgatgctaag aaaaacttga tcgaagttcc
    56101 tatggttgga acaacaatcc cacacgaagt tctttcagaa ttcggtggag ctaaagtatt
    56161 gttgaaacct gctgtagaag gttctggagt tgccgctggt ggtgcagttc gtgccgttgt
    56221 ggaattggca ggtgtggcag atattacatc taaatcactt ggttctaaca ctccaatcaa
    56281 cattgttcgt gcaactgttg aaggtttgaa acaattgaaa cgcgctgaag aaattgctgc
    56341 ccttcgtggt atttcagttt ctgatttggc ataagaaagg ggataaaatg gctcaaatta
    56401 aaattacttt gactaagtct ccaatcggac gcattccatc acaacgtaaa actgttgtag
    56461 cacttggact tggcaaattg aacagctctg ttattaaaga agataacgct gctatccgtg
    56521 gtatgattac agcagtatct cacttagtaa cagttgaaga agtaaactaa tgaagtttta
    56581 ggggatgtgc actgtaccat cccctaaaac tagatatagt catctatgat gacatcgtat
    56641 aggcgagttg atgggggaga caaccttttc tcccttatcg gcgctagcat tttacaaaag
    56701 aggagaaaat aaaaatgaaa cttcatgaat tgaaacctgc agaaggttct cgtaaagtac
    56761 gtaaccgcgt tggtcgtggt acttcatcag gtaacggtaa aacatctggt cgtggtcaaa
    56821 aaggtcaaaa agctcgtagc ggtggcggag ttcgccttgg ttttgaaggt ggacaaactc
    56881 cattgttccg tcgtcttcca aaacgtggat tcactaacat caacgctaaa gaatacgcaa
    56941 ttgtgaacct tgaccaattg aacgtctttg aagatggtgc tgaagtaact ccagttgttc
    57001 ttatcgaagc aggaattgtt aaagctgaaa agtcaggtat taaaattctt ggtaacggtg
    57061 agttgactaa gaaattgact gtgaaagcag ctaaattctc taaatcagct gaagaagcta
    57121 tcactgctaa aggtggttca gtagaagtca tctaagagag gtgacctatg ttttttaaat
    57181 tattaagaga agctcttaaa gtcaagcagg ttcgatcaaa aattttattt acaattttta
    57241 tcgttttggt ctttcgtatc ggaactagca ttacagttcc tggtgtgaat gccaatagct
    57301 tgaatgcttt aagtggatta tccttcttaa acatgttgag cttggtgtcg gggaatgccc
    57361 taaaaaactt ttcgattttt gccctaggag ttagtcccta tatcaccgct tctattgttg
    57421 tccaactctt gcaaatggat attttaccca agtttgtaga gtggggtaaa caaggggaag
    57481 taggtcgaag aaaattgaat caagctactc gttatattgc tctagttctc gcttttgtgc
    57541 aatctatcgg gattacagct ggttttaata ccttggctgg agctcaattg attaaaactg
    57601 ctttaactcc acaagttttt ctgacgattg gtatcatctt aacagctggt agtatgattg
    57661 tcacttggtt gggtgagcaa attacagata agggatacgg aaacggtgtt tccatgatta
    57721 tctttgccgg gattgtttcc tcaattccag agatgattca gggcatctat gtggactact
    57781 ttgtgaacgt cccaagtagc cgtatcactt catctatcat tttcgtaatc attttgatta
    57841 ttactgtatt gttgattatt tactttacaa cttatgttca acaagcagaa tacaaaattc
    57901 caatccaata tactaaggtt gcacaaggtg ctccatctag ctcttacctt ccgttaaagg
    57961 taaaccctgc tggagttatc cctgttatct ttgccagttc gattactgca gcgcctgcgg
    58021 ctattcttca gtttttgagt gccacaggtc atgattgggc ttgggtaagg gtagcacaag
    58081 agatgttggc aactacttct ccaactggta ttgccatgta tgctttgttg attattctct
    58141 ttacattctt ctatacgttt gtacagatta atcctgaaaa agcagcagag agcctacaaa
    58201 agagtggtgc ctatatccat ggagttcgtc ctggtaaagg tacagaagaa tatatgtcta
    58261 aacttcttcg tcgtcttgca actgttggtt ccctcttcct tggtgtgatt tccattttac
    58321 cgattgcagc taaagatgta tttggtcttt ctgatgttgt tgcctttggt ggaacaagtc
    58381 tcttgatcat tatctctaca ggtatcgaag gaatcaagca attggaaggt tacctattga
    58441 aacgtaagta tgttggtttc atggacagaa cagaataaaa gtatttactg aatcagtaaa
    58501 tactgaggga gtggaggttt aaactctgac atttgtaaga gttggatctc ccctcttcta
    58561 ttttgttttt aaataggggt gaaaagactt tttgcttcta tttaaaaata aaataaggag
    58621 atcaaatcat gaatcttttg attatgggct tacctggtgc aggtaaggga actcaagcag
    58681 caaaaatcgt agaacaattc catgttgcac atatctcaac aggtgatatg ttccgcgctg
    58741 caatggcaaa tcaaactgaa atgggtgttc ttgctaagtc atatattgac aagggtgaat
    58801 tggttcctga cgaagttaca aatggaatcg taaaagaacg cctttcacaa gatgatatta
    58861 aagaaacagg attcttattg gatggttacc cacgtacaat tgaacaagct catgccttgg
    58921 acaaaacatt ggcggaactt ggtatcgaac tggaaggtgt gatcaatatc gaagtgaacc
    58981 cagattgtct cttggaacgt ttgagtggtc gtatcatcca ccgcgaaaca ggtgaaacct
    59041 tccacaaagt tttcaaccca ccagttgact ataaagagga agattattac caacgtgaag
    59101 atgataaacc tgagacagtg aagcgtcgtt tggatgtgaa tatcgcccaa ggtgaaccaa
    59161 tcattgctca ctaccgtgcc aaaggattgg tccacgatat cgaaggaaat caagatatca
    59221 atgatgtgtt caaagacatc gaaaaagtat tgacaaattt gaaataaagc gtttttcaca
    59281 cttgcaaaaa atcgctacaa atgttatact gagatagtct gacttataat tgttgtctct
    59341 gttttcagag gcatcgaatc gaaatttatg gaggtgcttt tgcgtggcaa aagacgatgt
    59401 gattgaagtt gaaggcaaag tagtcgatac aatgcctaac gcaatgttta cggttgaact
    59461 tgaaaatgga catcagattt tagcaacagt ttctggtaaa attcgtaaaa actatattcg
    59521 tattttagcg ggagatcgtg ttactgtcga gatgagtcca tatgacttga cacgtggacg
    59581 tatcacttac cgctttaaat aatcgaaaaa cttggaggga taagaaatga aagtaagacc
    59641 atcggtcaaa ccaatttgcg aatactgtaa agtaattcgt cgtaatggtc gtgttatggt
    59701 aatttgccca gcaaatccaa aacacaaaca acgtcaagga taagatagaa aggagaaaaa
    59761 atggctcgta ttgctggagt tgacattcca aatgacaaac gcgtagtaat ctcattgact
    59821 tacgtttatg gtatcggact tgcaacatct aagaaaattt tggctgctgc tggaatctca
    59881 gaagatgttc gtgtacgtga ccttacatca gatcaagagg atgctatccg tcgtgaagtg
    59941 gatgcaatca aagttgaagg tgaccttcgt cgtgaagtaa acttgaacat caaacgtttg
    60001 atggaaatcg gttcttaccg tggtattcgt caccgtcgtg gacttcctgt ccgtggacaa
    60061 aacactaaaa acaacgctcg cactcgtaaa ggtaaagctg ttgcgattgc tggtaagaaa
    60121 aaataatata ggaggtaaaa gtcttggcta aaccaacacg taaacgtcgt gtgaaaaaga
    60181 atatcgaatc tggtattgct catattcacg ctacatttaa taacactatt gttatgatta
    60241 ctgatgtgca tggtaatgca attgcttggt catcagctgg tgctcttggt ttcaaaggtt
    60301 ctcgtaaatc tacaccattc gctgctcaaa tggcttctga agctgctgct aaatctgcac
    60361 aagaacacgg tcttaaatca gttgaagtta ctgtaaaagg tccaggttct ggtcgtgagt
    60421 cagctattcg tgcgcttgct gccgctggtc ttgaagtaac agcaattcgt gatgtgactc
    60481 cagtgccaca caatggtgct cgtcctccaa aacgtcgccg tgtataatca tcgcattaca
    60541 ctgcttttcg tttaagaggg agtaactaaa tgattgagtt tgaaaaacca aatataacaa
    60601 aaattgatga aaataaagat tatggcaagt ttgtaatcga accacttgaa cgtggctacg
    60661 gtacaactct tggtaactct cttcgtcgtg tactactagc ttctctacca ggagcagcag
    60721 tgacatctat caacattgaa ggtgtcttgc atgagttcga cacagttcca ggtgttcgtg
    60781 aagacgtgat gcaaatcatt ctgaacatta aagggattgc agtgaaatca tacgttgaag
    60841 acgaaaaaat cattgaactt gacgttgaag gtcctgctga aattacagct ggagacattt
    60901 tgactgacag tgatgttgag attgtaaatc cagatcatta tctctttaca atcggtgaag
    60961 gttcttctct aaaagcgaca atgactgtta acagtggtcg tggatatgta cctgctgatg
    61021 aaaacaaaaa agataatgca ccagttggaa cacttgctgt agattctatt tatacaccag
    61081 ttacaaaagt caactatcaa gttgaacctg ctcgtgtagg tagcaatgat ggatttgaca
    61141 aattaaccct tgaaatcttg actaatggaa caattattcc agaagatgct ttagggcttt
    61201 cagcacgtat cttgacagaa catcttgatt tgtttacaaa tcttactgag attgctaagt
    61261 caactgaagt gatgaaagaa gctgatactg aatctgacga tcgtattttg gatcgtacga
    61321 ttgaggaact ggacttgtct gtgcgttcat acaactgttt gaaacgtgcc ggtatcaaca
    61381 ctgtgcatga tttgacagaa aaatctgaag cagagatgat gaaagtacga aatcttggac
    61441 gcaagagttt ggaagaagtg aaactcaaac tcattgattt gggtcttgga ttaaaagata
    61501 aataaaggag gaatacatgg cttaccgtaa actaggacgc actagctcac aacgtaaagc
    61561 aatgcttcgc gatttgacaa ctgacctttt gatcaacgaa tcaatcgtga caactgaagc
    61621 tcgtgctaaa gaaatccgta aaactgttga aaaaatgatt actctaggta aacgtggtga
    61681 tttgcatgca cgtcgtcaag cagctgcttt cgtacgtaat gaaatcgcat ctgaaaacta
    61741 tgatgaagca actgataagt acacttctac tacagcactt caaaaattgt tctcagaaat
    61801 cgcacctcgt tatgctgaac gtaacggtgg atacactcgt atccttaaaa ctgaaccacg
    61861 tcgtggtgat gcagcgccaa tggcgatcat cgaattagta taaaatcatc aattttgttg
    61921 agtgttatga tgatggagtc ttgtgctctt agtctagctc tggtctaccg ctaggatttc
    61981 ggtcctagcg ggaacactca tcataagttg ggatagtaga cgcttgttta cgaaattgtt
    62041 tttttcttaa gaacaacttc gtaagcaggc gtttttgagt attttcgtta gaattatgct
    62101 atactatttg aaaagaatcc tgtttaatgt taaggtttct tattttaaga agaattggag
    62161 tttacttatg aaagcgatta taactgttgt tggtaaagat aaatctggaa ttgttgcagg
    62221 tgtttctggt aaaattgcag aattaggatt gaatattgac gatatctctc aaactgtatt
    62281 ggatgaatat tttacgatga tggctgttgt atctagtgat gaaaagcaag attttaccta
    62341 tcttcgtaat gaatttgaag cttttgggca aactttgaat gtaaaaatca atattcagag
    62401 tgcagcgatt ttcgaagcta tgtataatat ctaggaggtc atcatggata ttagacaagt
    62461 tactgaaacc atcgccatga ttgaggagca aaacttcgat attagaacca ttaccatggg
    62521 gatttctctt ttggactgta tcgacccaaa tatcaatcgt gctgcggaga aaatctatca
    62581 aaaaattacg acaaaggcgg ctaatttagt agctgttggt gatgaaattg cggctgagtt
    62641 gggaattcct atcgttaata agcgtgtatc ggtgacacct atttctctga ttggggcagc
    62701 gacagatgcg acggactacg tggttctggc aaaagcgctt gataaggctg cgaaagagat
    62761 tggtgtggac tttattggtg gtttttctgc cttagtacaa aaaggttatc aaaagggaga
    62821 tgagattctc atcaattcca ttcctcgcgc tttggctgag acggataagg tctgctcgtc
    62881 agtcaatatc ggctcaacca agtctggtat taatatgacg gctgtggcag atatgggacg
    62941 aattatcaag gaaacagcaa atctttcaga tatgggagtg gccaagttgg ttgtattcgc
    63001 taatgctgtt gaggacaatc catttatggc gggtgccttt catggtgttg gggaagcaga
    63061 tgttatcatc aatgtcggag tttctggtcc tggtgttgtg aaacgtgctt tggaaaaagt
    63121 tcgtggacag agctttgatg tagtagccga aacagttaag aaaactgcct ttaaaatcac
    63181 tcgtatcggt caattggttg gtcaaatggc cagtgagaga ctgggtgtgg agtttggtat
    63241 tgtggacttg agtttggcac caacccctgc ggttggagac tctgtggcac gtgtccttga
    63301 ggaaatgggg ctagaaacag ttggcacgca tggaacgaca gctgccttgg ccctcttgaa
    63361 cgaccaagtt aaaaagggtg gagtgatggc ctgtaaccag gtcggtggtc tatctggtgc
    63421 ctttatccct gtttctgagg atgaaggaat gattgctgca gtgcaaaatg gctctcttaa
    63481 tttagaaaaa ctagaagcta tgacggctat ctgttctgtt ggattggata tgattgccat
    63541 cccagaagat acgcctgctg aaactattgc ggctatgatt gcggatgaag cagcaatcgg
    63601 tgttatcaac atgaaaacaa cagctgttcg tatcattccc aaaggaagag aaggcgatat
    63661 gattgagttt ggtggtctat taggaactgc acccgttatg aaggttaatg gggcttcgtc
    63721 tgtcgacttc atctctcgcg gtggacaaat cccagcacca attcatagtt ttaaaaatta
    63781 agaaaatagg agaaatttta agttctattt aagattagat gtgtatacta taatcattaa
    63841 ataaagacct cctaatatta tttgaaacag ataacactga attagtttga atttgatttt
    63901 catctaatat ctttatttaa tgaactccta aactttttca taataatctc cttcaaaagt
    63961 cgcctgtatg ggtggctttt attttatcat tcatgatata atagaagcaa acggaggacg
    64021 gaaaatggta aaagtacgat tgtatttggt acgtcatggc aagaccatgt ttaacacgat
    64081 tggtcgcgcg caaggttgga gcgatactcc cttaactgct gaaggtgaac gagggattca
    64141 agagttagga atcggtttgc gagaatctga tctacagttt gagcgcgctt attcgagtga
    64201 ttctggtcgt accattcaga ccatgggaat tatacttgaa gaacttggct tgcaggggaa
    64261 aatcccttat cgcatggaca agcgtatcag agaatggtgt ttcggtagtt ttgatggagc
    64321 ctatgatggc gatcttttca tgggcattat tcctcgtatc tttaatgtgg accacgttca
    64381 ccaattgtct tatgctgaac tggctgaggg cttggtagag gtcgatacag ctggttgggc
    64441 tgaaggttgg gaaaaactca gtggccgaat caaggaaggc tttgaaataa ttgcaaaaga
    64501 aatggaagat caaggtggag gtaacgccct tgttgtcagc catggaatga ctattggaac
    64561 cattgtttat ctgattaatg gcatgcatcc gcatggtcta gataatggta gcgtgacgat
    64621 tcttgaatat gaggacggtc agtttagggt tgaagttgtc ggtgaccgta gttaccgaga
    64681 gctaggacgt gagaagatgg aagaaggttc tatttaatca gtctagactt gcttgccatg
    64741 agctagggat ttgataagaa tatcaagata agaaaaaaca gccgagggta ctcctttcgg
    64801 ctgtttttga tgtggaaaac taaagtgtaa tgctattgct tttagagatt ttcataaaca
    64861 agagcaagga acctactgtt agaacagtca ggatagttga caaggctgca gctacaccgt
    64921 aatttcctct gagaacctct gtataaatag ctacagtcat tgttcttgtt ttgacattgt
    64981 agaggaggat agaagtagag agttctgaaa tcagtgtgac ccaagatagg atggctccag
    65041 aaataatatc cgatagcatc attggagttg taatcttagc aaagatattg agacgactac
    65101 ttcctaagct ttcagcagct tcttcaatac ttggtgctat ttgttgtaag ctagcaacag
    65161 atgagcgaat agtataaggt aattttctgg cagatagaga cataatcaag atgaaagcag
    65221 tccctgtaat cataagaaat ccacttccaa atagaccaga gaaatgaagg caatccctag
    65281 aacggttcct ggtacaatat aaggtaccat actgaggctg tcaattaagt ttgtaaacaa
    65341 attccgtttt ctaacggcta ggtaggagat aaatgtcgta aatagaacaa ctagaactaa
    65401 ggcaatcaaa gggatacgaa tggtattgaa aatagcagat cccatacgat tgaaagctag
    65461 cttgtaactg tttggagaat aacctttaac aaataccata cctgatgttt ttaggaaaga
    65521 ggtataaatt aagtagattt gaggtaaaac agagataaag ataattccgt agactgttgc
    65581 ataaatggca gccatttttc cttttgtagt ttttttaggc tcaattggat ggagcagatt
    65641 catgctgaaa ctgtagcggt ttgcaatgtg tttttggata aggaaaattg ccaaggcaat
    65701 gataatcgcc ataattgcaa aagcagaatt tcctccaacc tcgctaataa attgggtata
    65761 aatcaggaca gggaaagtcc gatacccttc gccaatcaac ataggcgttc caaagtctga
    65821 gaatgctctc ataaatacaa gcaaggagct gctagtaagg ttggaactag gagaggtaaa
    65881 acaaccgtta cgataggttt aaatccgaag gaccccatgc tttcagctgc ttcaagtaga
    65941 gaattgtcaa tactgttcat tgttccagca acatatagaa ataccagtgg gaatagttgc
    66001 agtgtaaaga caagtacaat tcctttgaat ccataaatat cgatagctgg aagataaagg
    66061 gcatttgtca aaaatttagt gatgacctca tttcgtccca gcaagagaat ccaggagtag
    66121 gctcctacga aaggagctga catggaagca atgataatca atatttgtag aaatttcttc
    66181 cccttgaagt catacataga gaagagataa gctaataggg ttcctacaac taaggaagtg
    66241 acagtagcgg taatggaaac cctgaaactg ttgactagtg tctcagagta gtaggcttta
    66301 ctaaagaaag tgacaaaatt agctagtgag aattgtcctt catgtataag tgcttgcttg
    66361 agcacggtaa cgataggata aacgagaaag acaagatagg taagaaagag gaagaaagag
    66421 gaggctgtcc aaatatttag ttttttacat tccatggttg actcctttta tcaggttttg
    66481 ggaaccatct gcagaaaaga tgtttaattt ttgcgtattg attcgtagac gaatacgatt
    66541 gcctttttgt agatcttctt caaaagttga ttcttcacta acttgaattt ttgaggcaaa
    66601 acctgtctca atgaaatact ccgtatttag tccaagatag acgctatcgc taatagttcc
    66661 ttcgatatct ccagattcat ctttgataaa ctcttcggga cgaatgctta catgaatagc
    66721 ttgctcctca acctgatcaa gagctagcat tcgaagggca tagccatctg aaaagacgat
    66781 ataagcgccg tcgctccgtt tttcaagatt ggcagggata atatttgtgc gtccgataaa
    66841 ggttgccaca aactcattag ctggtttatg atagagttct tttggtcggc cgatttgttg
    66901 gatcacccca tctttcataa cagcaatttg gtctgaaata gccatggctt cttcttggtc
    66961 gtgggttaca taaacagttg taattcccac ttcgtgttgg atttctcgga tggtttgacg
    67021 catatccaag cgaagtttgg cctccagatt actaagtggc tcgtccatga ggagaacact
    67081 tggattaacc gctaaggcgc atgccaaggt gacacgttgt tgttgtccac cactgagttt
    67141 atcgggcttt cgatccgcat attgagcaat ttgcatgagt tcaagatact tgttggtctg
    67201 ttgaatcaat tcttcttttg gaaccttctt ttgcataaga ccaaaagcaa cgttgtctcg
    67261 gacagtcaaa tgtgggaaaa tagcgtagtt ttggaaaacc agcccgatat tgcgtttgct
    67321 gggttccata ttattgattt ttgtatcatc gaagtaaaat tctccatctt tgatactgtt
    67381 gaaacctgca atcatacgaa gaagggtcgt tttcccacat cctgaagctc caagaagggt
    67441 aaagagactt ccttttggaa ttgtaatgtt caaattctca ataacaggga catcgtggta
    67501 gatttttttg gcgttaataa tttcgatctc actcatagtg aacctctttt actgtttaga
    67561 ttggatatct gtaaagactt cgttgtattt cttaacgata tctgatttat tcttgatgac
    67621 ataatcataa tcttaagtga gtgttttgat tttgtcaatt ggtttcatgt tttcgcttgt
    67681 tttagcattt ttacgaacag gacggttagt agtggttgta ccaagtgtat cttgtacttc
    67741 ttgagagata ataaaatcga taaatttctt ggcattttcc atatttttag attttttaac
    67801 gatagcagca ctagaaggta ggaagacggt tccttctttt ggatagacta ccttaatgtt
    67861 agctccgtca tttaagagtt taactgctgg atcttcataa gagagaccaa cagtcatttc
    67921 tccatcagcg actgctttat agacaccaga tgaacttgaa ccgattttat agtatattga
    67981 aactagaata gtacacatct acttctaaaa cattgttaga aatcgatttg actgtcctga
    68041 ttaatttgtc ctgttcttat ttcattttac tataccatca ataagtgtga aaagatcttt
    68101 tacataagac caagccttat catctttgta accaccttga gcttgtagca tatttgttaa
    68161 ttgagcaaag gcgctagaag agtttgctgg gtcagcagtt gcgatttttc cttttagttc
    68221 aggtttgaga aggtcgctat atccttcgat gttcatgcct ttagttaaat cagggtggac
    68281 gattaaaaca ttaccatcta gtgtataagg agtagagaag ccagttgtgt tttgatattc
    68341 tttgataaca ttatcatttt cttttgaaat atagttttca aagagttctc cgtgggtagc
    68401 atattgtgta taagaaccac caaagataac atcagctaca ggaacttctt tttctgactc
    68461 tagttttttg aaaagttctc cagtaccagc ttgaatcagt tctattttga taccatattt
    68521 ttcttcaaag gcaggaatag ttgctccaat taagccttct gagtttggtc aataaacgac
    68581 tagcgaacca ccgtctcctt tatcagatga actgtcatcg gcagattcat tagaagaaca
    68641 agcagcataa tacatccatt tctttttcat gatggatacc tccgttgtgt tatttaagtt
    68701 tattttaaaa caatgtaagc gtttttaaaa cctacaattc tattctatag tgtattgaat
    68761 ctataacagt acac
//
LOCUS       DAVLTG010000005        62911 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLTG010000005 DAVLTG010000000
VERSION     DAVLTG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.005"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(143..853)
                     /locus_tag="VYN12_000334"
     CDS             complement(143..853)
                     /locus_tag="VYN12_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1414778.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(856..2547)
                     /locus_tag="VYN12_000335"
     CDS             complement(856..2547)
                     /locus_tag="VYN12_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1414779.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2559..3569)
                     /locus_tag="VYN12_000336"
     CDS             complement(2559..3569)
                     /locus_tag="VYN12_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414780.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINILTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3672..4739)
                     /locus_tag="VYN12_000337"
     CDS             complement(3672..4739)
                     /locus_tag="VYN12_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1414781.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESTVVKVLDKENAIQYGMIWGSGALVGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            complement(4764..5423)
                     /locus_tag="VYN12_000338"
     CDS             complement(4764..5423)
                     /locus_tag="VYN12_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1414782.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSSY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5645..5941)
                     /locus_tag="VYN12_000339"
     CDS             complement(5645..5941)
                     /locus_tag="VYN12_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414783.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLLEDNKID"
     gene            complement(5925..8084)
                     /gene="pfbA"
                     /locus_tag="VYN12_000340"
     CDS             complement(5925..8084)
                     /gene="pfbA"
                     /locus_tag="VYN12_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1414784.1"
                     /translation="MLKIVKKLEVLMKYFVPNKVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKVIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(9201..10427)
                     /locus_tag="VYN12_000341"
     CDS             complement(9201..10427)
                     /locus_tag="VYN12_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1414785.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(10470..11162)
                     /locus_tag="VYN12_000342"
     CDS             complement(10470..11162)
                     /locus_tag="VYN12_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1414786.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(11335..13086)
                     /locus_tag="VYN12_000343"
     CDS             complement(11335..13086)
                     /locus_tag="VYN12_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414787.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(13076..14821)
                     /locus_tag="VYN12_000344"
     CDS             complement(13076..14821)
                     /locus_tag="VYN12_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414788.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIEQGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(15027..15404)
                     /locus_tag="VYN12_000345"
     CDS             complement(15027..15404)
                     /locus_tag="VYN12_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1414789.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(15476..15932)
                     /locus_tag="VYN12_000346"
                     /pseudo
     CDS             complement(15476..15932)
                     /locus_tag="VYN12_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            16066..16893
                     /gene="xth"
                     /locus_tag="VYN12_000347"
     CDS             16066..16893
                     /gene="xth"
                     /locus_tag="VYN12_000347"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1414790.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            16905..17048
                     /locus_tag="VYN12_000348"
     CDS             16905..17048
                     /locus_tag="VYN12_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1414791.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            17048..17287
                     /locus_tag="VYN12_000349"
     CDS             17048..17287
                     /locus_tag="VYN12_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1414792.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDLYIYPHKFAVLDPDGYFLRFSE"
     regulatory      17670..17765
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18165..18746
                     /locus_tag="VYN12_000350"
     CDS             18165..18746
                     /locus_tag="VYN12_000350"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1414793.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            18746..20008
                     /locus_tag="VYN12_000351"
     CDS             18746..20008
                     /locus_tag="VYN12_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1414794.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LFGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(20058..20519)
                     /locus_tag="VYN12_000352"
     CDS             complement(20058..20519)
                     /locus_tag="VYN12_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV1414795.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(20516..21280)
                     /locus_tag="VYN12_000353"
     CDS             complement(20516..21280)
                     /locus_tag="VYN12_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV1414796.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(21461..21865)
                     /locus_tag="VYN12_000354"
     CDS             complement(21461..21865)
                     /locus_tag="VYN12_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1414797.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VYITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(21935..23416)
                     /locus_tag="VYN12_000355"
     CDS             complement(21935..23416)
                     /locus_tag="VYN12_000355"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1414798.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            complement(23435..24613)
                     /locus_tag="VYN12_000356"
     CDS             complement(23435..24613)
                     /locus_tag="VYN12_000356"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1414799.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPATISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVSLDIQTLGELDEWAVDQYSYLIKDENRLKRVR
                     HAVLENQRTLKAQVALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            24777..25784
                     /gene="galR"
                     /locus_tag="VYN12_000357"
     CDS             24777..25784
                     /gene="galR"
                     /locus_tag="VYN12_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1414800.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLNQ
                     E"
     gene            complement(25831..26868)
                     /locus_tag="VYN12_000358"
     CDS             complement(25831..26868)
                     /locus_tag="VYN12_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1414801.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(26869..27222)
                     /locus_tag="VYN12_000359"
     CDS             complement(26869..27222)
                     /locus_tag="VYN12_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1414802.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(27466..28356)
                     /locus_tag="VYN12_000360"
     CDS             complement(27466..28356)
                     /locus_tag="VYN12_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1414803.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            28489..29025
                     /locus_tag="VYN12_000361"
     CDS             28489..29025
                     /locus_tag="VYN12_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1414804.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKDYETTTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(29191..29997)
                     /locus_tag="VYN12_000362"
     CDS             complement(29191..29997)
                     /locus_tag="VYN12_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1414805.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(30342..31862)
                     /locus_tag="VYN12_000363"
     CDS             complement(30342..31862)
                     /locus_tag="VYN12_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1414806.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(31855..32583)
                     /locus_tag="VYN12_000364"
     CDS             complement(31855..32583)
                     /locus_tag="VYN12_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414807.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(32598..33362)
                     /locus_tag="VYN12_000365"
     CDS             complement(32598..33362)
                     /locus_tag="VYN12_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1414808.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            complement(33366..33809)
                     /locus_tag="VYN12_000366"
     CDS             complement(33366..33809)
                     /locus_tag="VYN12_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1414809.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            complement(34491..34787)
                     /locus_tag="VYN12_000367"
     CDS             complement(34491..34787)
                     /locus_tag="VYN12_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1414810.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            complement(34809..35873)
                     /gene="pepA"
                     /locus_tag="VYN12_000368"
     CDS             complement(34809..35873)
                     /gene="pepA"
                     /locus_tag="VYN12_000368"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1414811.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            36274..36975
                     /gene="galE"
                     /locus_tag="VYN12_000369"
     CDS             36274..36975
                     /gene="galE"
                     /locus_tag="VYN12_000369"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1414812.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37398..38357
                     /locus_tag="VYN12_000370"
     CDS             37398..38357
                     /locus_tag="VYN12_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414813.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            38347..39303
                     /locus_tag="VYN12_000371"
     CDS             38347..39303
                     /locus_tag="VYN12_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1414814.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYILLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            39300..40052
                     /locus_tag="VYN12_000372"
     CDS             39300..40052
                     /locus_tag="VYN12_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1414815.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            40148..41113
                     /locus_tag="VYN12_000373"
     CDS             40148..41113
                     /locus_tag="VYN12_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414816.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(41338..41580)
                     /gene="yidD"
                     /locus_tag="VYN12_000374"
     CDS             complement(41338..41580)
                     /gene="yidD"
                     /locus_tag="VYN12_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1414817.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(41580..42302)
                     /locus_tag="VYN12_000375"
     CDS             complement(41580..42302)
                     /locus_tag="VYN12_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1414818.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(42289..42858)
                     /locus_tag="VYN12_000376"
     CDS             complement(42289..42858)
                     /locus_tag="VYN12_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1414819.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(42877..43605)
                     /locus_tag="VYN12_000377"
     CDS             complement(42877..43605)
                     /locus_tag="VYN12_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1414820.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(43605..44345)
                     /gene="xerD"
                     /locus_tag="VYN12_000378"
     CDS             complement(43605..44345)
                     /gene="xerD"
                     /locus_tag="VYN12_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1414821.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(44336..44797)
                     /locus_tag="VYN12_000379"
     CDS             complement(44336..44797)
                     /locus_tag="VYN12_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1414822.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(44794..45315)
                     /locus_tag="VYN12_000380"
     CDS             complement(44794..45315)
                     /locus_tag="VYN12_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1414823.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(45291..46262)
                     /locus_tag="VYN12_000381"
     CDS             complement(45291..46262)
                     /locus_tag="VYN12_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1414824.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(46259..47053)
                     /gene="racE"
                     /locus_tag="VYN12_000382"
     CDS             complement(46259..47053)
                     /gene="racE"
                     /locus_tag="VYN12_000382"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1414825.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(47260..47508)
                     /locus_tag="VYN12_000383"
     CDS             complement(47260..47508)
                     /locus_tag="VYN12_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1414826.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(47764..49389)
                     /gene="treC"
                     /locus_tag="VYN12_000384"
     CDS             complement(47764..49389)
                     /gene="treC"
                     /locus_tag="VYN12_000384"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1414827.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(49567..51534)
                     /gene="treP"
                     /locus_tag="VYN12_000385"
     CDS             complement(49567..51534)
                     /gene="treP"
                     /locus_tag="VYN12_000385"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1414828.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETLVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            51719..52429
                     /gene="treR"
                     /locus_tag="VYN12_000386"
     CDS             51719..52429
                     /gene="treR"
                     /locus_tag="VYN12_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1414829.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(52462..53265)
                     /locus_tag="VYN12_000387"
     CDS             complement(52462..53265)
                     /locus_tag="VYN12_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1414830.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(53278..54171)
                     /locus_tag="VYN12_000388"
     CDS             complement(53278..54171)
                     /locus_tag="VYN12_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414831.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIVEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(54183..54914)
                     /locus_tag="VYN12_000389"
     CDS             complement(54183..54914)
                     /locus_tag="VYN12_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1414832.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSEPNSVV
                     QKDEAKRLLKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQ
                     VSIKHKVPVFGGSTEMIAVGGLYNYGTNYEELGRQTARMLIHVLKGEKPENIAVELPE
                     KLELHTNQEMADALGIDISKLEGKE"
     gene            complement(55404..56330)
                     /locus_tag="VYN12_000390"
     CDS             complement(55404..56330)
                     /locus_tag="VYN12_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414833.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(56341..57408)
                     /locus_tag="VYN12_000391"
     CDS             complement(56341..57408)
                     /locus_tag="VYN12_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414834.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(57417..58343)
                     /locus_tag="VYN12_000392"
     CDS             complement(57417..58343)
                     /locus_tag="VYN12_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414835.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(58343..59839)
                     /locus_tag="VYN12_000393"
     CDS             complement(58343..59839)
                     /locus_tag="VYN12_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414836.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(59906..61885)
                     /locus_tag="VYN12_000394"
     CDS             complement(59906..61885)
                     /locus_tag="VYN12_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1414837.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSVYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(62467..>62911)
                     /locus_tag="VYN12_000395"
     CDS             complement(62467..>62911)
                     /locus_tag="VYN12_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1414838.1"
                     /translation="YDIISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKT
                     DSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFHHLFLHVVGNCVRTGRK
                     QLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
BASE COUNT        18777 a        14010 c        11423 g        18701 t
ORIGIN      
        1 aaatattcta ttttacctaa atcaaaattg attttataat ctttcataaa aacctctgag
       61 caaaaatcta ctcaaaaatt agatgattaa aacatctaaa aaacaaaagg acaaaaacat
      121 ctgtcccttt gtttactaaa tttcagctaa tttcttcgac ataaataaca cctacaatat
      181 tagcaatttc ttccatcagt cgaagatgtt caaatctacc tgataattcc agagtaataa
      241 atgacgctat ttttttgtcc ggaacatcaa agtattcaat tctgtcagaa ttaacatctc
      301 caaacgctgt tcttgaatcg gtcattctga taccattttc tgcacaataa accaatacac
      361 gattataggc ttctgtagat ttaaccacta tatacaattc aatcatttta gaacgatttt
      421 gcagatattt ttttagtggt tggaacatgg atatcacacc ccaaacagaa atggctacta
      481 aaagagctcc ctcataaaaa cctactccaa tagctaatcc aattcctgcc gaagcccaaa
      541 tgcctgctgc agttgtcaga cctgtaattt tctttttatc tgtaataaga atcgttccag
      601 cgcctagaaa acccacacct gatataactt gagctcctaa tcgtgtagga tctcctgtcc
      661 caaatttata agatacgtat tcattcgtca tcataatcaa acatgcagct agacaaacaa
      721 tactataagt tcggatgcct gcaggctggg atttgctccc tctctctaaa ccaattatac
      781 taccaatgac tactgataaa acaatcctga caactatttc aatatttgat aacccaagac
      841 tagtggctgt catgattatt tccttacttt acgccccggt ctttgtgtga agtataatac
      901 cgttccagaa ataatcatca gaacaattgt ataaacaaat accagagctt gtgcattaga
      961 tgttgctgtt tcatcacctg cagatcgaat cgtaatacct aatggttgag ctaggggatg
     1021 gtaaaggaat acagataagt cgaagtcagt taataaagag ttaaagttta aagcaataac
     1081 agagagaaca accggtaaaa taaatggaat gataaccttc atcatagtat aaaaaggtga
     1141 agcacccata cttcttgctg catcttccat ctcatcatca acactaaata aaatagcacg
     1201 taccattcta taagaaaatg ggatttttac aactatatat gcaataagta gaattaccaa
     1261 actacctacc aaaatctgat tcaagacaag aaattgtggc tgattaaaag taaataataa
     1321 acttactgct aaaagcgtac ttggtagtaa ccaaggaagt agagcaccat attcaaataa
     1381 gaaatcaaaa cgagatttat gttttctgac aacacgagca aatacaactg cgagaattgt
     1441 tgctgttgtc gcagcaataa tagaataaat aaagctgacc aagaatggag agaatgccgc
     1501 actattacta aagaataagc gataattttc taaagtaaag tttgataatg ttaagttacc
     1561 tgtttgaatt gcaactggat ctgtaaatga gtataatact ataaaaatta gtggaagcat
     1621 gaaaactgtg aacaatccat atgctacaat gtgagcaatg atattccaag gcttagacgc
     1681 aattttttgt tttttaagag gcgctttagt cttagagata gaaatataat ttccaccttt
     1741 ttctatctta ttcatgatag taagcaaaat tgtagttgca atacctaaaa taattgcaag
     1801 taaggcagct aaatcacgag aattccccat ccctgcaaat gtaataatca ttggatttat
     1861 agtttgaaat tctttaccac caacaatcat gggtgctgct actgcagata aaccactaag
     1921 aaaaaccata atagtaagtg caaatagagt tggaattaag gttggtaaca ctacttttcg
     1981 gaaaacagta aatggttttg ctcccatatt tcgagcagcc tcaatagtgt gatagtcaac
     2041 gcttcgaatt gtatttgtta aaaacaatgt atgattagca gttcctgaaa atgtcataat
     2101 gaataagact gcaccatacc caataaacca gttagagtct aaagaaggga taacattttg
     2161 taaaaatttt gtaatcaatc cataaggacc atagacaaat ttatatccag tcgctaaaac
     2221 cactcctcca taaattaaag aggtcatata acctaatttt aaaattttag cacctttaat
     2281 atcaaagtac tctgtaaata gaacacaaag aatacctacg acattaactg taataatgag
     2341 tgaaaatgct aacttaaaac tgttcataat actctgaagt gccctctgag attttagaac
     2401 acgatgtaca gcatcaaggg aaaattctcc tccttttaca aatacattca ctactagatc
     2461 aaagtttgga taaataataa atgttactaa gaaccagatt aaccctaaac gaataagcca
     2521 atcttttaaa tttaatttat gacgcatact gcacctcctt aaaattgcag aacgtctgat
     2581 ggtgtgataa ataattccac actttctccg acagatctaa tagcagcctg actatcaata
     2641 cttgttacat taagaatctg actttcagaa acttttattg tatagtgaat tgtaactcca
     2701 gaaaactcaa catcaataat tgtccctttt agaataaaat cttgttcagt ttcacgattg
     2761 aatcgaactt tctctaatcg aatgtatcct tttttatcct ctaagaaaac gcttgtattt
     2821 ttcaataata cttcgtggac tgtttcatcg gtcaaaatat taatatctcc aataaaatca
     2881 catacaaatt cagtttgaga attatgataa atctctactg gtgtaccgac ctgttcgatg
     2941 tatccattgt taaagactgc aattctatca gataaagtca aggcttcctc ttgatcatga
     3001 gtaacatata aagtagtaat acctaactct ttttgaagtc ttttcaactc ttttctcaaa
     3061 tctacacgta attttgcgtc aaggtttgac aatggttcat ctagacaaag aattttaggt
     3121 tcaagaacca gagcacgagc caatgctacc ctttgttgtt gacccccaga taattctgat
     3181 acattacgct gtaactgttg atcagagatc ttaatttttg ctgccactgc tgatacttta
     3241 gctttaataa catctggagc taccttctta acttttaaac caaatgcaat attatcaaaa
     3301 acagtcatag ttggaaatag cgcataagat tgaaatacaa taccaattcc acgcttttca
     3361 ggttccaaat gagtgacatc tgttccatta acttcaatac ttcctgatga tggatctaaa
     3421 aaacctacca atgctctcaa agtagttgat ttaccacatc ctgaaggccc aagaaatgta
     3481 aagaattccc cttcatgtat atctaaattc agattatcaa ttgcaacaaa atcaccatat
     3541 ttaatttgaa tattatcaaa tttaatcatc tcactaactc cctctattac taaaccaaaa
     3601 gcctctcttt atttcttcct taaatttaga aataatagag agacttggac ataaaaaata
     3661 actcttattt cttattgtac gtattctaat tcagcttttt ctacccattc atccaaatgc
     3721 tttccaacag cttcccagtc aatattttgt ggtttcactt gatcaacaaa ttttttcgta
     3781 tcttcaggta actcttttag ggcatcttta tttgcaggaa tagatccaaa ttttttacta
     3841 tattctactt gaatttctga ttgaccaaac caatcaataa attctttagc taacgcttgt
     3901 tttttactag tgcttaaaac catagtttgt tcagttacaa atggtacacc aatctcagga
     3961 gtcataactt tgaattcaac attttgttct ttttgaccaa ctagagcccc ggacccccag
     4021 atcataccgt attggatagc gttttctttg tctaatactt taacaactgt gctttcacct
     4081 ttttgtagtg tataggcatt tgcaaagtat tcttttgcaa cttcccagcc cttttccgat
     4141 actcctaaat cacctttttc atcaagataa cgaactagaa tacttgcgta aatggcgcgt
     4201 ccagtcccac cagttaagcc ataaatggaa tattgtccct tatatttact agctaactct
     4261 gtccagtctt ttggcatttc ttttgcatca ggagctccaa tcaataccaa gggttgaaca
     4321 ataactgggt tataataatt atctttatct gataaagatt gatcaatttt atctaaccat
     4381 ttaggcttgt actgtactag taatttttga tctctaattt tatttgagtc aacagcacca
     4441 attccaaata ccatatctgc aactgcatta ttcttctcag caataacacg gtctgctaat
     4501 tgagcgccag cgatatcaac catttttata ttaaaaccag cttcttttgc tttagcagtt
     4561 aaccaatcac cacgaccatt tgagactgag ttcgaataga ttactaattc ttgactttta
     4621 tcagcttttt cttcagatga agaagcagtc gtagaatttg aacctccaga gcaagcagca
     4681 agtgtagtaa gagcaactcc cgttgcaagt acagtagacc aaactttcat ttttttcatg
     4741 ataagttctc cttttttatt attttattta aatttttcgt gatatggaac aaattgtctc
     4801 atatcttcaa atacagtata gtcaatacgg tttacagtaa tagttggaat cttctctaat
     4861 aaaatttcag ttaattctgc tctgacttta gtaaactctt cttcctcctc ttcggttaga
     4921 ggaatccgaa gatacccaat tgaaatatgg aattgatatc tatcatgatt agggaaacaa
     4981 acacctgctt tttctgagac ataagtacga atttcttcta atctctttgc agaagcttca
     5041 tctgcaggtt caactagtat gttttgtttt cccatttcag ttatacgcat atgaatttct
     5101 tcatccaaca atggaaaaat ttcaagttgt ttagcaaagt aatcatgtat ttcctgtaaa
     5161 ggtgtatcta gaggaagatt actgctccaa aactccgttt cacgattttc atggcacaac
     5221 aattcaatta cagtcatgtg aatagaattc cttggagtta aagtaaactt atcgataaat
     5281 ggtaattctc tataacttga ttgaataata tcaacaactt ccatcaaatc ttgtttagta
     5341 taaagatttg ctacaactgt attcccaggg aaatgattaa attccccatt ctctttgaac
     5401 ttaatttttg ttaagttttt catataaaga ccttcttttt tatatttgac atcggtgtca
     5461 tcgtgtttac attatacaat gaaaccgttt cctttgtcaa gcgctgtcaa acattttttt
     5521 taatttatct ttcattaaaa ggttaagtaa tttttccaaa atacagcact catatagaca
     5581 gtatcatcaa ttatagccat tgggattttt tgattgccaa ttccatgtat ctctacacat
     5641 gtcttcaatc gattttgttg tcctccaata atttatatga gtttaaaccg atttcatctt
     5701 taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct ttacaattaa
     5761 ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct atctcctctt
     5821 tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt tgtgaaccta
     5881 caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt atctttacca
     5941 taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt taagaatagt
     6001 tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac tatttcttta
     6061 gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata gtttacttct
     6121 tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt atctttactt
     6181 gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt agattgtttt
     6241 tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac aattttgtaa
     6301 agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac aggttctttc
     6361 ccatttgcat tagatttgat gaatgatata tacttaccgg ataaattata aaattggtta
     6421 tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt accaccgaat
     6481 atactattct ctgagactac taaattatca ctaactcgta ataattcaat atttggttgt
     6541 tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc tgatactttt
     6601 cctaaatatt ctgcactatc ttttgcaact cgtatcactt ttgttttagg atcggcaata
     6661 ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc tttagtgttt
     6721 ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac actctctcct
     6781 ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc tgtaaaacgt
     6841 acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt agaggggttc
     6901 tgtgtcgaca atgtttgata gtgtgtgcca attgctgtta ctaattcccc agatttatca
     6961 cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc atcatcattc
     7021 aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc cttacttatg
     7081 atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga attatcaact
     7141 aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc cttgaatgtt
     7201 acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga agaatttata
     7261 agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat atcaatcgta
     7321 ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc atcatctgta
     7381 aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc atttagaatt
     7441 gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat ttcttttact
     7501 aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc tgcagcatct
     7561 attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc accataatct
     7621 tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact tataacatct
     7681 tccttataac tcttattttc attagtagat gttactgtag attcaactgt tctgttgtct
     7741 aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact taacgaatta
     7801 tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt ttgattaaca
     7861 gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt agccatcggt
     7921 gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat tgaaattgcc
     7981 aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctt attaggaaca
     8041 aaatatttca tcagaacctc caattttttt actattttta acaattgatt attacttttc
     8101 ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc caaattgaat
     8161 tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc tcttcaaact
     8221 aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct atagtagact
     8281 gaaactataa tagtacacct ctacttctaa aacattgtta gaaatcgatt taactgtccc
     8341 gattaatttg tcctattctt atttcatttt attatatcta caacctcaaa gcagggtttt
     8401 gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa agtgatgcta
     8461 tctttcttag cttgaatata aaatatccca tttactatat ttaaatttgt tgatatgttg
     8521 taaattataa atgaaagaac aaatatcttg tcatacaagc attcgccagg gatatttaca
     8581 tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc ttaaatagac
     8641 cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct aaaatactgg
     8701 aatagggcat ataggtaatc gtagacaagt gttttataga ttgtctcgca ggagatgcaa
     8761 gcatcactaa acatatagag tatttgtatt attataatat taacattcta taaattctat
     8821 catgcaaaag aatgactaga acatgaaaga caggcacaaa actttgaaca atattctgaa
     8881 aacaaaaaaa gacgcgagtt tccacaatct cactcatgga aactcacgtc tttcaaaaaa
     8941 tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc tagtaaggat
     9001 tctaaatgct acaccaaatt gctcacatct tatttcaaac cacgggactc ccacaagaaa
     9061 ggaaaatcct ataaaaattc tctctctgag gagaaaggag cctcaactac aggtgtaaac
     9121 tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg acaggatcac
     9181 tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc agaaactgtt
     9241 ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg aagagggagg
     9301 gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc aaatccaaga
     9361 ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc aattcctgct
     9421 ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc tacacgggtg
     9481 atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg atggatgcga
     9541 gaacctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg caacaaactt
     9601 ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat gttgcactta
     9661 taggctggtg taacgatatc gtattcccat gaccccaatt gcatcttggc aagagcatcc
     9721 ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc gtcatcaatc
     9781 actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt cttaacggca
     9841 tggaatgaga aggaagtaaa gtcagcgata gaaccagaag gttgtccttt ataagtagat
     9901 cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt ttgccacttg
     9961 cttgaagcag taaagaagtc acgttttttc tccacgactt ggaacaaacg gtcataatcg
    10021 caaacaatcc ctgcgagctc tactgggata atcaccttag ttttctcagt gatagcttgc
    10081 tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat gacaggggtt
    10141 gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg aacgatgact
    10201 tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc tgtcgcagag
    10261 ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc cagttctttt
    10321 gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccgctacttc agcaatttct
    10381 gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga tttgctcctt
    10441 ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac ggtttgaaac
    10501 atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt atagcgcatc
    10561 ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt ctccgtcatt
    10621 tgactgatga tggtgtcctc atccttgtag ttgatgctgg ctggagaggt aattcctgct
    10681 tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg tggcacttca
    10741 ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg aggcagttcg
    10801 tccaaacgga cacgtcggat gaaatttcca accttggtaa tacggctatc gttagcagaa
    10861 gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacggaactt ccaaatcttg
    10921 aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc cttgctatcc
    10981 aacttgatcc aaatgctcaa gatgagaaag atgggagagg ttagaaccag taagaccaag
    11041 gccaaaaacc agtccaagca acgcttgaaa atcagcgaac ccttcctttt agagacaagc
    11101 tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc ccatttcagc
    11161 atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta taccacaaaa
    11221 tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta ctcaatgaaa
    11281 atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag attttcaaag
    11341 agtataggcc atggcccctg cctgcaaact atacatcttg tgataggttc ctcccagagt
    11401 caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga catagatgca
    11461 gttggcgtct tgaatagtag aaaggcggtg agcgatagca atagttgttc ggccctgtct
    11521 catcttcgcc agagaagctt gaaccaaact ttctgtttca gagtcaatat tggctgtcgc
    11581 ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg caagaagctg
    11641 gcgctgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt acccctgagg
    11701 aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa cctgctcatc
    11761 actgatttct tggtacatgg cgatattgga cttaatagtt ccatgataga ggaagggttc
    11821 ctgtaagacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc tgatatccac
    11881 atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga cattgataat
    11941 agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct tattaacaga
    12001 gaaagaaatg tcatccagaa tcggatgttt accgtcatat gagaaacaca catgttcaaa
    12061 acggatattg ccttcttgga ctttggcttg cccattttct tgaagaggtt cataggtcct
    12121 ctcgtctatc agggcaaaga cacgacctgc agaaaccata gccgtttgca gagttgaaaa
    12181 gttttgcgtc acctcaatca aggggtcaaa aaggcggttg atgtactgga taaaggcata
    12241 catggtcccg accgttatcc cgatagaaaa accacggtag ccaaagtagg ccatcaagac
    12301 tgcatagcct agaagtttca gcaaactcat ggcaggtctc aaaaagaggg catccaaggc
    12361 tacagaacgg ttggcgtaga ccaagtgttc ttggttgatt tcatcaaatt ctgcctgcag
    12421 gcgcttctct tgattaaagg cctgaataat cctgattccc tcgatattct ctgccagctt
    12481 actattgata tctgacaaga gacttctggt tttctcgatg attttcactg acttttttcg
    12541 atagagattg accaaaagga aaatcaaagg aagaaagagc aagactaaag ccgtcaaacg
    12601 aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg ctgagataaa
    12661 gctggataaa atcccagaaa acatatcact gatagtctcg gtgtcatttg tcaaacgaga
    12721 gacgatagag cctgctggcg tcttgtcaaa ataagacatg cccaactttt ccatattggc
    12781 aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa agagaagatt
    12841 gccgacatac tgaactacag tttgtaggat gtagagacca tagtagacca gcaaaacggt
    12901 aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag ccacgagggg
    12961 tatgacactt ttaatgaccg tcgtcgctag gagaaaactg agtgccaaaa aggtcaggag
    13021 tccataaggc ttgagataag acatcaagcg cttcaataca gcccattgtt cttgtttatt
    13081 ctgcatcttc ttctcctttc atttccaact gctgagactg gtaggtttgg gcataccagc
    13141 catccatcgc tagcaagtct tcgtgcgtac cttgttcgat aatttgacca ttttgtagaa
    13201 ctaaaataaa atctgcatgg acaacagcac tgaggcgatg ggcagtgata atggttgtct
    13261 tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg gcatctacgg
    13321 cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc cgactcatag
    13381 ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc agcgtatcaa
    13441 atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta gcttcctcga
    13501 ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt gaagtcgcaa
    13561 agagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc agacgatagt
    13621 cccgaatatc gtgaccgttt agataaatgg cacccttatc cacatcgtat tcacgcaaga
    13681 ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc agtgtttgcc
    13741 cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa gcaaagctgt
    13801 caatggtata ctccaaacgc ccattttcaa taccatccag aggaaactca gggtcttgta
    13861 caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc cctcgctgag
    13921 tagtattaaa gaggaagccg atggccataa gaggccagac cagcatatcc aaatagctga
    13981 taaaggtgac tagattacca actgtaatct gcccttcctg aaccatcaag gagccaacca
    14041 aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca aagagactat
    14101 catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc tgaaaagact
    14161 tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat acggactcct
    14221 gtaccttgtt attgagttca gaaaaagcag tttgggattc gccaaaggcc ttatgagtct
    14281 ttctccctag gcgactagtc gcataggcca tgaaaggtag ggggagaatg gcaacaagag
    14341 tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc gtgatagagg
    14401 catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg atatcattgg
    14461 ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac gacatttttg
    14521 tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag gtcccaagga
    14581 tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt agcaagtaaa
    14641 ataggctaag aaggaggtcc tgctgggtta attgccccga tgtgatggca tcaataaccc
    14701 gccccataac cataggagga atgagattga ggacggaaac caagatcagg gccacaattc
    14761 cgactagata acggcgtttt tctaacttga aaaaccacca aagtttttga ataatggaca
    14821 taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga aaatcaaaga
    14881 gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg tagatagaac
    14941 tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga agagattttc
    15001 gaagagtaca agaccccagg tttttcttat tcataagtta cgactgtaac agcacccttg
    15061 tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact gaggttatca
    15121 agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat cacaccgtca
    15181 gtcacaactg gatacttagg attttcatct cccatttgca caacgatgag ttgcccattt
    15241 tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct acgaagtttg
    15301 agggatacat ccgatgcaga caaaccaact gaacgacagg cttctgggtc aatattccca
    15361 tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg aacattgttg
    15421 ttgagctatt tgagagtcaa gaccagtttg attaaaattt cgatataatt aagtgtcatt
    15481 tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc tctaacaggt
    15541 acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc ttgataagtg
    15601 cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact cccaaatctt
    15661 tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa acttgattgt
    15721 tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagatc tgaaatcatg
    15781 accaactcac gaaattcgct tcccttttta tcatggtatg ccttgaaagc aaaaaaaact
    15841 gtcacagcta atagaacaat cccaaagcca accatgatac cattttgctg accgatttgg
    15901 ctgagtacat agtcataaga gtagaatttc atgtattttc actccctttc ataaaatcat
    15961 tcttaattat aaacgaaaga gagtaatttt tcaaaccata cgttggggaa atagatcttt
    16021 ttttggtata ataaaatcta taatctgaat gaaaaaggta actttatgaa acttatctca
    16081 tggaatattg attccctaaa cgctgcccta actagtgact cagctcgtgc caaattgtcc
    16141 caagaagtcc tacaaacctt ggtcgctgaa aatgctgata tcattgctat ccaagaaacc
    16201 aagctttctg ccaaaggacc tacaaagaaa cacgtggaaa ttttagaaga actcttccca
    16261 ggctacgaaa acacgtggcg ctcttcccaa gagcctgccc gtaaaggcta tgctggaacc
    16321 atgttccttt ataagaaaga acttacaccc actgtcactt tcccagaaat cggtgcccct
    16381 tctaccatgg acttggaagg ccgcatcatc actctagaat ttgatgcatt tttcgtgacc
    16441 caagtttaca caccaaatgc tggcgatggt cttaaacgct tggaagaacg ccaagtctgg
    16501 gatgtcaaat atgcggagta tttggctgaa ctagacaaag aaaaaccagt ccttgcgacc
    16561 ggtgactaca acgtagccca caatgaaatc gaccttgcaa atcctgctag caaccgccgt
    16621 tcacctggat ttactgacga ggaacgtgct ggatttacca acctattggc aactggattt
    16681 actgatacct tccgccatgt tcatggcgat gttcctgaac gctacacttg gtgggcacaa
    16741 cgcagcaaaa cttctaaaat caacaataca ggctggagaa tcgactactg gctcacaagt
    16801 aaccgtatcg ctgacaaggt cactaaatct gatatgattg actcaggtgc tcgccaagac
    16861 catacaccga ttgtcttgga aattgacttg taaggatttt ctatatggac tacaatgcgg
    16921 tcattcccga gtttcttgta tcgaatatcg aacagtcccg gtccttctac tgtggtttac
    16981 tgggttttag gattgaatac caacgtccag aagaaaactt tctctttctc ttgaagagtg
    17041 tcaactaatg ttagaggagg gaacaaagga tcaactagct gaactgacct acccctttgg
    17101 tcgtggagtc aatctctcct ttggcataaa ggatgttcca aaactctatc aaaaagtgat
    17161 ggaggcaaac tatcctattt atcgtccctt gaccaaaaga aagtttcgtg tcagtgatct
    17221 ctatatctat cctcataaat ttgcagtttt ggatccagat ggctattttt taagatttag
    17281 cgagtagaat aataaaaatt gggaaaagtc tttaaagtta gaaaaaggca tattgtcagg
    17341 tgtctaaaaa cttgatagta tgccttttat gatggaaaaa tcttctaata ctcttcgaaa
    17401 atctcttcaa gccacgtcaa cgtcgcctta ccgtaggtat atgatactga ctctgtcaat
    17461 tctatccaca acctcaaaac agtgttttga ggttgtggat agcttcctag tttgctcttt
    17521 gattttcatt tagtataaat gttagcttac aatggagttt ttgttcaccc tctcttctgt
    17581 ttgttcgttt tttaaaccaa aacactaaca aaatagttga tttctaaagt tatttagtgt
    17641 aaaataaaaa cattggctca agcctattta aaattgaata tcgttttact tgtttatgtc
    17701 gtgaattggc acgacgtttc tacaaggtgc cggaacacct aacaataagt aagtcagcag
    17761 tgagatatgg ccgtttttgc catgtctatt taggggactt acttagagat taagtaggtc
    17821 ttttttgaat atttttaata tttcccttaa ttagtgcgga cgagaggtga aattatcctg
    17881 tgaataattt caggaatcca gggaatttca tccctaattt ttgagcccct agctctttca
    17941 tttctaggct taggctaaaa tagttccccg aactatttta ctctcaaaaa tcccgtcata
    18001 gacaataaca agattattgt ctatgatacc actacaacgg gaaatatttg ataagactat
    18061 tacgagcgaa gcgagtctta tcaaatatat agtattagca aaagggatca ctatagaaac
    18121 atttcaacaa caagtaaatt agcttttaga ctttaggagg tcttatgaaa ttattagaag
    18181 atcgcatcct caaggatggg catatcttgg gtgataacat cctcaaggta gattcctttt
    18241 taacccacca agttgacttt agcttgatgc gagagattgg taaggttttt gcggaaaaat
    18301 ttgctgctgc cggcattacc aaggtcgtaa ccattgaagc gtcgggtatt gccccagccg
    18361 tttttacagc tgaagcctta aacgttccca tgattttcgc caaaaaagct aagaacatca
    18421 ccatgaacga aggcatctta actgctcaag tctactcctt taccaagcag gtgaccagca
    18481 ccgtttctat cgctggaaaa ttcctctcac cagaggacaa ggttttgatt atcgacgatt
    18541 tccttgctaa tggccaagct gctaaaggct tgattcaaat catcgaacag gccggtgcca
    18601 cagtccaagc tatcggtatc gtgattgaga aatccttcca agatggtcgt gatttgcttg
    18661 aaaaagcagg ctaccctgtc ctatcacttg ctcgcttgga tcgttttgaa aatggtcagg
    18721 tcgtatttaa ggaggcagat ctctaatgca aactcaagaa aaacactcgc aagcagccgt
    18781 tcttggcttg cagcacttac tagccatgta ctcaggatct atcctggttc ccatcatgat
    18841 tgcgacagcc cttggctatt cagctgagca gttgacctac ctgatttcta cagatatctt
    18901 catgtgtggg gtggcaacct tcctccaact ccaactcaac aaatactttg ggattggact
    18961 cccagtcgtt cttggagttg cattccagtc ggtcgctccc ttgattatga ttgggcaaag
    19021 ccatggtagt ggcgctatgt ttggtgccct tatcgcatct gggatttacg tggttcttgt
    19081 ttcaggcatc ttctcaaaag tagccaatct cttcccatct atcgtaacag gatctgttat
    19141 taccacgatt ggtttaacct tgatccctgt cgctattgga aatatgggaa ataacgttcc
    19201 agagccaact ggtcaaagtc tcttgcttgc agctattact gttctgatta tcctcttgat
    19261 caacatcttt accaaaggat ttatcaagtc tatctctatt ttgattggtc tggttgttgg
    19321 aactgccatt gctgctacta tgggcttggt ggacttctct cctgttgcgg tagctccact
    19381 tgtccatgtc ccaattccac tctactttgg gatgccaacc tttgaaatct catctattgt
    19441 catgatgtgt atcatcgcaa cggtgtctat ggttgagtca actggtgttt atctagcctt
    19501 gtctgatatc acaaaagatc caatcgacag cacgcgcctt cgcaacggtt accgcgcaga
    19561 aggtttggcc gtacttttcg gaggaatctt taacaccttc ccttacaccg gattttcaca
    19621 aaacgttggt ttggttaaat tgtcaggcat caaaaaacgc ctgccaatct actacgcagc
    19681 tggtttcctg gttctccttg gactgcttcc taagtttggc gcccttgccc aaatcattcc
    19741 aagctccgtc ctcggtggtg ccatgctggt aatgtttggt tttgtatcaa ttcaagggat
    19801 gcaaatcctc gcccgtgttg actttgctaa caatgaacac aacttcctta tcgcagctgt
    19861 ttcaatcgct gcaggtgtcg gtctcaacaa cagtaatctc tttgtcagca tgccgacagc
    19921 cttccaaatg ttcttctcaa acggaatcgt cgtagccagc ctactcgcta ttgtcctcaa
    19981 tgccgtatta aatcataaaa agaaataaga aaaagaggtg cgagcctctt ttttgttgac
    20041 aaaataaaaa catctaccta ttcatatatg ctagtgtcat agtcctgaaa atcatctgca
    20101 tcaagaacaa tttcacaact cttatacttt tctcttacaa gtcgttcggc ttcatctgga
    20161 ttttcagcct ctatacttac taaacgtgat aaagtttctg taatttctac tgtatacttt
    20221 ttcagtttta gattgctttc caataattca cctattaaca ataatctatg ataggagcta
    20281 tgtagccact ctggcaattt atctcctact tcccacccat atttttcctt catcaaagct
    20341 agttgttttt cgtcaccaaa tttcatattt tcagataacc atctcacaca atcgggatct
    20401 gataaggtac agacgattaa acttaggtta tcgtaacggc tttcagtttc ataatcaggc
    20461 cagatgactt ttaagaaatc atacacctct tctgatgcaa caagttgttt cgttttcata
    20521 atttccgata ctttcctcta cctttaaatt ctattatttc tttgtctctt aatatttgaa
    20581 gctgttgcct aatcttttct ttgatatgat tgttcttaac aaagatattt tttaggtcac
    20641 tttcaaaacg atacatatct tcaagggtga attctgaacc ctctatctta tctatacaat
    20701 ttagaatttc tattgtccaa cctcttgatg acagagagct cttccttaaa aataaacctt
    20761 gcttaaattc ttttgtaact ttttctggat ctctaacttg tccatcttgc acaagaaata
    20821 tccttccttt agaaggtact tgtgataaat caatgttaca accaatccaa cctgctcgtc
    20881 tagcagttgg tgcaagtggt tttctttgaa taatcgattt cggtgtaaca aattgcttcg
    20941 gaaggacaag aaagttattt acctcaaaat tttttgtgta agttaaaaaa aagaaattag
    21001 gattattatc tgcctgcaca cgcttcatca tcgttgcata agcaccatca ttgattgttg
    21061 atgaaaaatt tccttttttg ctctttagtt caaactcctc actacaatga ttacagtaaa
    21121 aatctgctac aggccgatta ttttcaaaat gatttaaggg attgttccca caattagggc
    21181 aataagactg acgataaacc caatcctccg ttaagatacg tgccttttgg ctattacttt
    21241 tataggtttc tactaattct aaattaaagt gtaattccat ttaaaaattc ctcactaata
    21301 tgagaactca ctcgatataa gcaattaaaa tctactataa ctagtatacc acatatatgt
    21361 acctattaca tttgtatttc atcactctct tttatatttc cttctaacat atctcataaa
    21421 ttaaaaatga gtgagataaa tttatcccac tcacctttct ttatatactt acccgtcttt
    21481 cctcagacct ttggcctgtg acaaacatgg taaaggttgc tttacagaca tttctgccct
    21541 cttgattggt gatatacaca tccatcacac aggttgtacg accttgatgg acacattctc
    21601 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    21661 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagcg
    21721 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    21781 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    21841 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaacga cactatgata
    21901 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtgaaatt ccgacctgtt
    21961 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    22021 caagtacacg cacaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    22081 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    22141 caactgtaac agcttctcct acaagatagc tagcgacttg ctccacttct tctttcagac
    22201 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    22261 gttggacatc cttgtgggga tgatagatgc catcaggatg ctctgctgaa gtctgattgt
    22321 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    22381 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    22441 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    22501 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    22561 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    22621 aatgatcgtg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    22681 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    22741 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    22801 aatactggaa cccccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    22861 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    22921 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    22981 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taagcgatat
    23041 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    23101 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    23161 gacaaggagt caccaagtcc atcagttcag taccaaggat ttcacgcgca gtctgactat
    23221 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    23281 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    23341 tcagatagat tcgatccatt tcctcaaatg agctttcaga aatgacatgt gttacaaatt
    23401 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    23461 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    23521 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    23581 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    23641 gggtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    23701 tcatcaagcg tccaaatgtt tccaaatctc ctgcttggag tgctacttga gctttgaggg
    23761 tacgttggtt ttcaagcaca gcatggcgaa cacgtttcaa acgattttca tctttaatca
    23821 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagagtctga atatccaagg
    23881 aaacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagaat
    23941 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    24001 gtggcaccaa atcatactct aaggtgttgg tatcaaggta aatagcacgt tgatcagccc
    24061 ccataccaat agcaaactgg tccatgatac cagagttgac tccgataaag ttattttctg
    24121 tttgttttcc gattttaacc aaatccaaac gctctaattt taaatcaaag agatgctctg
    24181 ccactacccc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    24241 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    24301 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    24361 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaaaactt
    24421 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagtagca ggaaaaacgt
    24481 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat acggcctggt gaaaagaaag
    24541 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagagtt tcagcagtaa
    24601 gatgttgtgt catatgattt ctcctttgac tgtccgttaa gccaccttaa cgtgtaatcg
    24661 ttttcttcta ttgtatccaa ggaatttccc aaggtcaatc ctttttacta aaattttagt
    24721 aaactatcag taaaaagaag aaaaatatga tatactaacc taatcaagga ggatttatgg
    24781 ctaccttaaa agacattgca cagctagcct ctgtctctat cgcgaccgta tcccgcgtcc
    24841 tcaaccgcga ccagagccta tctgttacag aagaaaccag acaccgtatt ttaaccgttg
    24901 ctgaagagct gggctacacc aagcacctca agacaggcga gtcccataaa cccaagcaaa
    24961 agattgccat tattcaatgg gtcagcgaac aaggggagct ggacgacctc tactactacc
    25021 agattcgcct aggaatagaa aaaagagccc aagagttgga ctatgatatc ttgcgctatt
    25081 ttaatgacca tccttttacc ttaagcgagg aagtgattgg gattctctgc atcggaaagt
    25141 ttagtcgagc tcagatttct gcctttgaag aataccaaaa gcctcttgta tttctagaca
    25201 gcgatacact ttccctggga catacctgta ttatcacgga tttttacact gctatgaaac
    25261 aggttgtcga ttatttcctc agccaaggaa tggaccgtat cgggattcta acaggccttg
    25321 aagaaacaac tgaccaagaa gaaatcattg aggataagcg gctggaaaat ttcagaaact
    25381 acagtcaagc aaaaggaatc tatcatgatg aactgatctt tcaaggaaac tttactgccc
    25441 agtctggcta tgacttgatg aaggaagcca ttcagaactt gggagaccaa ctcccaccag
    25501 catttttcgc agccagcgat agtttagcca tcggtgccct tcgtgcgctc caagaagctg
    25561 gaatcagcct accagaccgt gtcagcctca tttcctttaa cgacaccagc ctgaccaagc
    25621 aggtttatcc tcccctctcc agcatcacag tttatactga agaaatgggg cgagcaggta
    25681 tggatattct taacaaggaa gtcctccacg gtcggaaaat ccctagcctg accatgttgg
    25741 gaaccaaact gacattaaga gaaagtaccc taaatcaaga ataggataac ataaaaaacg
    25801 aataggagtt ttagaactcc tattcgtttt ttattcgatt ataatcatag acttaatagt
    25861 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    25921 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    25981 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    26041 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    26101 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcatctgc
    26161 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    26221 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    26281 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    26341 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    26401 tgtcggcatg acatctgcaa gagtcaaaag ggacttgagc atcccttctg tatagtcaga
    26461 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    26521 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    26581 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    26641 tttcaccgtc gtaatggctt ccccagcttc ttcaacaatc ccaatcgctt cgtgtccact
    26701 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    26761 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    26821 gcttgcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    26881 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    26941 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    27001 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    27061 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    27121 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    27181 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    27241 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    27301 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    27361 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    27421 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    27481 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    27541 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    27601 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tgtacaatgg catttttttc
    27661 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    27721 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    27781 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    27841 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    27901 agctacccac cctagcgtat cttccagaaa atgcaaactc agaatagact cattctttgt
    27961 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    28021 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    28081 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    28141 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    28201 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    28261 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    28321 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    28381 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    28441 aaaacgtcag ctttattcag ttctgaacaa tttgcctcaa gtgtccatat gactaacatt
    28501 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    28561 gctaaggact acgagaccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    28621 tccacctttt actgtcacta tgagagtaaa gagcttcttc tggatcagct ctgccgctac
    28681 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    28741 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    28801 gactacttcc tccgtcaact ccagagagag cttgagcacc acgtctattc cgtgctagct
    28861 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    28921 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    28981 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    29041 cagttgtctt atttctaggt tactgagttt tttatctttt caacaacaaa agaggacccg
    29101 ccgatcctct ttttcatact ataaatcctt gattatcaac tatatctgtt ttaatcgaaa
    29161 tctcaaaaca gcactttcaa acatcttttc ctagttaagt aaatcagtat tctgcttagc
    29221 tgccttgctc cattgatacc aaccaactag actgttaatg agataaatta gatatttccc
    29281 ttgaatttgc aggctttctc cccaccagag atagattgaa aaaacattgg tagccgccca
    29341 gaatatccac tgttcacggt aaacagctgt catgaggatt tgccctaccc cattggttgc
    29401 atctgtgatt gaatcacgat agggacgatt ggcaccaata gactgataaa tgaagccaaa
    29461 ggccaaccac caaagcacac taatggaaag atactttgtc cagcccttgc cgtccagttt
    29521 acgcgcgaca aactcctgct tttccttctt aaactgtgcc tgataaatcc aaactagaag
    29581 tccaattggc tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat aaaagccttt
    29641 ctgtagggcc aaaataaggt aaataacaga gttaatcaag ccaaaaagat aattacttgc
    29701 tcgaccttcc gatacaaaga ttacacagat aatccctgtc aagctacaaa tcatcccaat
    29761 ccagtcaaca atacgatgtt cgtaaaccaa ctccagccag agaggaaaac ttcctaaaac
    29821 cagcaaataa atccactggg caaaactacg atgggcaaag aggtcatccc agatagcctt
    29881 catagttcct gaaaatccta aatcagccat agccgcaacc atacgacggt aaccacctga
    29941 catttcacct agggttgttt tgatattttc aattttcttt tgcaaataag tatgcatcat
    30001 ttctcctttt gtttttaaag agccgtgtct ggatagactt tcggacgcaa cgctctatta
    30061 gataatgaac tgcctataca caagatttct aaccttagtc gacatgagct gaaacctctt
    30121 atttgttaag tagttcacaa aatattatac acctatttta tgaatagtca actgtcttta
    30181 cagtaaaatt ttagaaaatc atgaaaattt tctctttctt tccattttaa gtgacattca
    30241 gtcattctca catcaaaaaa gcccagacga aattgtctga gcattctttt atctagtcgt
    30301 ttaaggaagt tgagttcagt atgtttaaag tctctgtccc atcatttctt caacaaacct
    30361 tgttcttgga gaaactcctt ggctacttgc tttgctgact tgccttcaac accgacttgg
    30421 tagttgagct ggctcatctg gctttctgta atcttaccag ccaatgtatt aagaactctt
    30481 tccaactctg ggtgtttctt gagaagagct tctttcatga gtggagcccc ttgataaggt
    30541 gggaagagtt gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa ttccgcatca
    30601 gtcgaatagg catccgtgat ttgaatatcc cctgactgaa ttgcctgata acgaagagct
    30661 ggctgcatag tcgccacatt gagattgaga ccatacattg attgcaagcc cttatttcca
    30721 tcttcacggt cgttaaactc aagcgtaaag cctgccttca gctgcccttc cacttttttc
    30781 aaatccgaaa tggtcttcaa gccatattct tgagcaatct ttttcggaac agctacagca
    30841 taggtatttt gataagacat aggtttgaga taggctagat gatcctgctt ggcaatgcca
    30901 tcacgcgcca cttgataaac ctgctctggc tcatgactca ccttgggtga tggttgaagc
    30961 aaactttcag tcaccgtacc ggtaaattca ggataaatgt caatatcacc ttttttcaga
    31021 gcttcataaa ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt catgctggta
    31081 ttttcttcaa tcagcaattt atacatatta gccaaaattt ctggttctgg gcctattttc
    31141 ccagcaataa tcaagttttc cttctctttt tgagccaaaa gggctggact ataagacaga
    31201 cccagtaata aagccatcaa ggcaaaacca gagaaaatcg tccgcaattt cgctttttcc
    31261 attactttta gtaggaagtt aaaggcaata gctagcactg cagaagaaag ggccccaatc
    31321 aaaatcaaac tggcattatt acggtcaatt cccaacagga taaaggaacc cagtccccct
    31381 gccccaatca aggtcgccaa ggtagccgta ccgataatca agaccgctgc cgtccgaatt
    31441 ccagacatga taacaggcat ggcaagtgga atttcaaact tcttgagacg ctcccatctg
    31501 gtcatcccaa aggcaatccc agcctcttgc aggttcggat caattccctt cagcccagta
    31561 atagtatttt gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa tgccggtaaa
    31621 gtcccaattc ccatcaaggg aataaagagt cccaacaagg ccagagacgg gatggtctgg
    31681 aaaatccctg caatctgtaa gacccaatcc gccaacttct catgatagcg aagataaaca
    31741 gccaagggaa tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa ctgcaaatgt
    31801 tgagataggg ctgtcaacca atcaccaaaa cgatcctgaa aagttgcaat taaattagtc
    31861 atgaatacta cctccaaaca agtctgcaac aaagtctgtt gcaggagctt ttaaaatagt
    31921 ctcaggattc gacacctgac gaatctctcc atcctgcaaa acagcaatac gatctgccaa
    31981 ctttaaggct tcatccgtat catgagtcac aaaaatcgtt gtcatcccaa actctttatg
    32041 taattctttt gtcagaacct gcaactgctt gcgagaaata gcatccaagg ctgaaaaggg
    32101 ttcatccatg aggagaatct tgggctgacc aatcatagct cggacaatac cgacccgttg
    32161 ctgttctcca ccagatagct cacttggaag tcgatgccca tactcagcta ctggtaatcc
    32221 aacttttgcc aaaagctctt ctgttttttg agcaatttct tccttagtcc aacccttcat
    32281 ttcaggaatg agagcaatat tttcctcaac tgttagattg ggaaagagag caatagcctg
    32341 taaaacatat ccagtagtaa gacgaagttc acgctcatca tagtctttga tgcgcttgcc
    32401 atccatataa atatttccat cagttggttc caagagacgg ttaatcatct taatcatggt
    32461 cgtcttacct gacccagaag gcccaactaa aaccatgaac tccccattct caatctgtaa
    32521 attgacatct ctcaagacat ctttttctgt gtagcgcagt gctacatttt tgtattcaat
    32581 cattctttgt cctcaattta aaacttccct cgattagtca agtcttctac cttaggtatg
    32641 acttccttat tatcccaatg ctccacaatt ttcccgttct ctaaacggaa gatatcgtac
    32701 tgggcataag caacgccatc aatctgagtc tgaccatagc taaccacata gtttccttgt
    32761 cctaagagtt ggaaaacaaa gtcaaaagtg acactatatt cagccacata gtttttataa
    32821 gcagcacttc cttgtccaat ctcatgatta tgctgaatca aatcgtctgc cacataatca
    32881 ctccactgct ctagctcccc attttggaaa gtttctgtca agaaacggcg aaccagcttt
    32941 ttattttctg ctttcttgtc caaatccttg atttcaaaat ctccaaaaat ttgatctagt
    33001 tggtcatttt caggtgttcg atagtagtca atgacatccc aatgctcaac aatacgacca
    33061 ttctcatccg cacggaaagt atccgtcgtc acccattgag cttctccacc attcagatat
    33121 tgatgaacat gaacaaagac cagattgcca tcctcaatgg tgcggacaat cttaatctga
    33181 cgctctggat gacgctcaaa gaaatctgca aagaaggctg caaatccttc tttcccgtca
    33241 ggaacacctg tcgaatgttg gatataggta tcccctacag actgggcttg agcctcagca
    33301 actcgtccgt cttgaatggc atggatgtat aggttgtgag catttttcac ttgttgtgac
    33361 atattctaaa cctcattttc cttctctttc agatttgcca aaattctttc ttgaaaacct
    33421 tcaaattggt gaatttcttc ctctgaaaat cctttgtaaa agatagtatc caatttctga
    33481 ctgacacgat gccccacttc tttctggaac ttgcctaact ccgttaaaac taaatacttc
    33541 ttacgcttgt cttttccaca cggactaaca attacaagct tttgttcctc tagctttttt
    33601 atcatagtcg tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc tgtcgcagtt
    33661 gcgcagccag tttcactatt ccataaaacc gctaaaatct tgccctgttc acccctataa
    33721 agagcctcag gatcttgact cagtaacttt tgaaaaatcc gcccattcaa caaacgaata
    33781 tgatgggcta gcaaatgact atctttcata acacctccaa tttatttcga tatcgaaatg
    33841 aataaaataa ttgtaacact catcgttcta actgtcaact atttcgattt ggaaataatt
    33901 tttgataatt attcacacca ccatactccg gctcaactaa cttttaacga gagtttctaa
    33961 attccttcgt cctccagtct acaaaagcct tccatccgta ctatcctatt ttttatgagg
    34021 ggacacattt ttcctatcag atcatttatt ttaaagatag aagtaaatca taattgcttc
    34081 catctgttct tttatagtat attgaagttg gactagggca ctgtatcttc taaaacattg
    34141 atagaaagcg atttgaattt cccaatcaat ttgttcgtat ttatagcatt ttgaaactag
    34201 aatacgacgc catgactgct aaaagatttc tataaattca tttgatttcc ctaatcaatt
    34261 tgttcatatc ttatttcatt ccgctataat ttcaccttac cctatctttt tcgtagcacc
    34321 cttcaaacag cctatcccct accgtttgac gattcctcac ttcactccac ttccattaca
    34381 gaagtttctt cactactatg gtctcggctg acttctcatg attccttgtt actactattt
    34441 gaacgctcac gagataggtc ttataaaaaa tgctttgatc cacaatggaa tcaaagcatt
    34501 ttaaaaagtt cctcatacat aagcgcagaa gtcgcagttc ctctgtactt ggcttcttct
    34561 cttttgacaa agcgagccaa gttgagcaac tcaggtgctg gatgtttggg atttaggagc
    34621 aattcacgat tgaccaggct tgagagacga actgcctgca attgctcatt tgtagtaggc
    34681 agttttttag tagtctctag gagagcagca actaaatctt cactcaaatc atgtcgagca
    34741 tgattgtaaa gatcttttat aaggctttct aggtttggtt ctaccatccc taccacctcc
    34801 cttatggttt aataatgttt aatcaaatca accgttgaac gatccaattt cttcaccaag
    34861 gcttgtaaga aagcttgcgc ttctaggaag tcatccattg catagagggt ttggtgagaa
    34921 tggatataac gagcgcagac accgatagtt gttgatggga caccaccatt tttcagatga
    34981 gctgcacctg catctgttcc gcctttacca cagtagtatt ggtacttgat accagcttct
    35041 tcagccgttg tcaaaaggaa atccttcatc cctgggagaa gcaagtgacc tggatcatag
    35101 aaacgaatca aggttccatc tccaatcttg ccttgaccac cgtagacatc acctgctggt
    35161 gagcaatcaa ctgcgaggaa gacttctggg tcaaacttgg ttgtagaggt atgagcgcca
    35221 cgcagaccaa cttcttcttg gacgttagaa cccagataga gttcattgcc gagtttttga
    35281 cctgataaag cttcagctag ctcgcttacc atgaggacac cgtagcggtt atcccaagct
    35341 tttgagatga tatttttttc attggctgtc aaaattgcag aactatctgg tacgatggta
    35401 tcaccaggac ggatgccaaa actttctgcc tcagccttgt ccgcaaaacc accatcaaaa
    35461 acgatatcgg caatggctgg catggttggt cccccctttc cacgagtcaa atgcggagga
    35521 acagaacctg aaatcacagg aatttcatga ccatcacgag tcaagagttt gaaacgttgg
    35581 ctgctaacca ccatggggtt ccagccaccg atttctacga cacggaaggt accatctggc
    35641 ttgatttcgc tgaccataaa accaacttcg tccatatgag aagcgaccaa gacgcgcggt
    35701 gcatccacag cttctgaatg tttgatacca aaaataccac ccaagccatc tgtcaccact
    35761 tcatccacat gcggtgtcaa cttttcacga agataagcac ggacaggcgc ttcatgacct
    35821 gagactgcag caagttctgt tacttcttta atttttgaaa ataatgttgt catttcagtt
    35881 ccttctttct ttcatccatt ttaccacttt ttataggaga aggatagtgg gaaggtggat
    35941 ttctaagtta gtatcttagt cctgctctat cttagaaaag gatagtattc tcttgcatgt
    36001 agtgcaaaat ctagtaaaca ttccaaaatt aactcgaata tttatttcca aacaaaaaaa
    36061 caatacacca tcaaagttgt ttggattttt catgaaattt acagaaaata gttgacttcc
    36121 ctttcttctt tctttaaata tatagttggt tgagtttgga atagtacgct gtagctgctg
    36181 aaacatttct agaaattaat ttgactttcc taatagagtt gttcatatct tatttcaatt
    36241 tactatagta caaaactaga aaaggaaaaa atcatgacca aaacaattct tgttacaggt
    36301 gggactagct acattggctc ccataccgtt aaagctcttt taaatgctgg ctatcaggtg
    36361 catgtcctcg ataatctctc cacaggaaat cgagcggctg tggatagtcg tgctagcttt
    36421 aaagaactgg atgtttatga tgctagcgcc ttaaaggctt acttagaaga aaatcagatt
    36481 gatgctgtcc tccattgtgc aggtgaaatt gttgtgagcg aaagtattga aaatccaagt
    36541 aaatacttca ctgccaacgt tgctggtatg aaccaagttc tcaaagtctt atctgaagtt
    36601 ggcattcaaa aaatcatgtt ctcttcgact gcttctctct atggaaataa ctgtattgac
    36661 aagccggtga ctgaagatac cctgctcgac cctgtcaacc cttatgcaga gacaaaactg
    36721 atgggcgaac gaatgattta ctggatggcc aatcgctacg actggaaata tgttattttc
    36781 cgttacttta atgttgctgg ggctgaaatg gatgcttcaa acggtctgcg tgtgaaaaat
    36841 ccaactcaca tcattccaaa tatcaacaag accgcattgg gacaacatga tagcttaaaa
    36901 atatttggag atgactacga tacacgtgac ggttcatgta ttcgagatta catttatgtc
    36961 ttggaccttg cataggctca tgttaaagga atgaactacc tatttcaaga agacagttct
    37021 tctcaaatct ttaacttagg aactaaaaaa ggctatacta tcaaagaaat ctttaaaact
    37081 gctgaagaat tactaaatta aaaaatccca cacgagattg ttgctcgacg tgctagtgac
    37141 ccagccaatg tcctagcaga tgcttcaaaa gctaaacaat atcttgattg gacggctagc
    37201 tactccctcg aagatattat tttatcagat taaggtaaaa acattttaga ataggataac
    37261 aaaggagaaa gtcttgttgc tctctccttg ttgtatttat taaattgtca gaaattttat
    37321 tgacagatta gaaaaataat gttacattta tatccgcaga tatctttcga taccaaatct
    37381 acatgaaagg acggggtatg aaactttctc attatttaat tggcttactt ctactcctag
    37441 tctttctctc tattagcatt gggaccagtg atttttcatg gggaaagcta tttgatttcg
    37501 accagcagac ctggctcctc tttcaagagt cccgtctccc aagaactatc agtattctcc
    37561 tgactgcctc tagtatgagt atggcaggcc ttctcatgca gactattacc caaaatcagt
    37621 ttgctgcacc gagtacagtt ggaacgactg aagccgccaa actgggaatg gtgctgagcc
    37681 tttttgtctt tccatcggct agtctgaccc aaaagatgct cttcgctttt gtttcatcca
    37741 tcgtattcac cctcttcttc ctagccttta tgaccatttt tactgtaaag gaaaggtgga
    37801 tgttgcctct gattgggatc atctatagcg ggattatcgg ctcagtcaca gaagttatcg
    37861 cctatcgttt caatctggtt cagagtatga ctgcctggac ccagggctcc ttctccatga
    37921 ttcagaccca tcagtatgag tggctcttct taggcctcat catcctgata accgtttgga
    37981 aattatccca aaccttcacc atcatgaatc tagggaaaga aaccagcgag agtttgggga
    38041 tttcctactc cctacttgaa aaactggccc tctttctggt ggcgctaacg acaagcgtca
    38101 ccatgattac cgtgggtggc ctaccatttc tcggagttat cgttcccaat cttgttcgca
    38161 agcgctatgg agataatcta agtcaaacca aactcatggt cgcactggtt ggtgccaatc
    38221 tagttctggc ttgcgatatc ctatcccgag ttctgattag gccctatgag ttgtctgtca
    38281 gtctcttgct aggaatcatc ggtagtctcg tctttatcct acttctctgg agagggggac
    38341 gaaaagatgc agactaaaag caaacatacc aagctcttct ggattctcat tattcttgcc
    38401 atcggagctt gtcttctcta cttttggccc atcactcact tgtcagcctt tgcttggaag
    38461 ttgcgttccc aaaagatcat cgtttatctc ttggtagcca tcgcgactgg gatttcgacc
    38521 attagttttc aaaccctgac ggaaaatcgc ttcctgacgc ctagtatttt gggaattgaa
    38581 tccttctaca tcctactaca aaccctacta ctggtttttg aaagcaagtt tcttcaactt
    38641 ggcaaatccc ctatcttaga attcctagtc ttacttcttg tccagtccct cttctttctc
    38701 gccttacaag gttacttgaa gacactgatg aagcaagacc tggtcttcat cctgctgatc
    38761 tgtctagcgc tcagaagtct ctttcgaaat atcagcacct tccttcaagt cctaatggat
    38821 ccaaacgaat acgataaact gcaaaatagt ctttttgcct cctttcaaca tctcaacact
    38881 tccatcctag ccatcggttc tctgatcatc ctcgctttga caatcttttt ctttcgaaaa
    38941 gcagtcgttc tagatgtctt gcacctgcaa agagaaacgg ctcagatatt gggactcgat
    39001 gttgaaaaag aacagaaaga gctcctctgg ggaatcgtgc ttttgacctc aacggccact
    39061 gccttggtag gacctatggc cttcttcggc tttatgctgg ccaacctcac ctacctgatt
    39121 gtcaaagact atcagcacaa gttactcttt atagtggcca ttctgattgg atttattagc
    39181 ttaaccttgg ggcaagcctt gattgaacga gtctttgcac tggaaattcg tatcagtatg
    39241 atcattgaga gtgtgggtgg cttcttattc tttatcttac tatataggag gtctcgtcag
    39301 tgaaactgga aaacattgac aaatccattc aaaaacagga tattttgcaa ggcatttcgc
    39361 ttgaagtcag tcctcaaaaa ctgacagcct ttattggtcc aaatggtgct ggaaaatcga
    39421 ctctcctctc catcatgagc agactaacca agaaagatca gggagttctc agtatcaaag
    39481 gacgtgaaat cgagagctgg aattcgcaag aactggccca agaactaacc atcctaaaac
    39541 agaaaatcaa ttaccaagcc aaattgactg ttgaagaact ggtcagtttt ggacgttttc
    39601 cctacagccg aggtcgactt agatcagaag actgggaaaa aatccgagaa actctgaact
    39661 atttggaact gaccaactta aaagaccgct acatcaatag cctgtcaggg gggcaactcc
    39721 agcgcgtctt tatcgctatg gtactggccc aggatacgga ctttatcttg ctggacgaac
    39781 cactcaacaa tctcgatatc aagcaaagcg tcagcatgat gcagattctt cgacgactgg
    39841 tggaggaact cggcaagacc attatcatcg tcctccacga tatcaacatg gccagtcagt
    39901 atgcagatga aattgtcgcc ttcaaggacg gccaggtctt tagcaaggga agaaccgatc
    39961 aaatcatgca ggctgaccta ctcagtcaac tttatgagat tcccatcacg ctagctgata
    40021 tcaatgacaa aaagatctgt atctatagct agtaacataa aagctcaagt tagagaacct
    40081 tcagtctctt agtcaataag attaagagac tccctaaatc gttatcacat tttaaaaagg
    40141 agaaattatg aaaacatccc ttaaacttta tttcactgcc ctagtggcca gcttcttgct
    40201 cctacttggt gcatgtagta caaactcaag cactagtcag acagagacca gtagctctgc
    40261 tccaacagag ataaccatta aaagttcact ggacgaggtc aaactttcca aagttcctga
    40321 aaagattgtg acctttgacc tcggcgctgc ggatactatt cgcgctttag gatttgaaaa
    40381 aaatatcgtc ggaatgccta caaaaactgt tccgacttat ctaaaagacc tagtgggaac
    40441 tgtcaaaaat gttggttcta tgaaagaacc tgatttagaa gctatcgccg cccttgagcc
    40501 tgatttgatt atcgcttcac cacgtacaca aaaattcgta gacaaattca aagaaatcgc
    40561 cccaaccgtt ctcttccaag caagcaagga tgactactgg acttctacca aggctaatat
    40621 cgaatcctta gcaagtgcct tcggcgaaac tagtacacaa aaagccaagg aagaattggc
    40681 caagctagac aagagcatcc aagaagtcgc tactaaaaat gaaagctctg acaaaaaagc
    40741 ccttgcgatc ctccttaatg aaggaaaaat ggcagccttt ggtgccaaat ctcgtttctc
    40801 tttcttgtac caaaccttga aattcaaacc aactgataca aaatttgaag actcacgcca
    40861 cggacaagaa gtcagctttg aaagtgtcaa agaaatcaac cctgacatcc tctttgtcat
    40921 caaccgtacc cttgccatcg gtggggacaa ctctagcaac gacggtgtcc tagaaaatgc
    40981 ccttatcgct gaaacacctg ctgctaaaaa tggtaagatt atccaactaa caccagacct
    41041 ctggtatcta agcggaggcg gacttgaatc aacaaaactc atgattgaag acatacaaaa
    41101 agctttgaaa taagccactt caaactcaat ttaatactca atgaaaatca aagagcaaac
    41161 taggaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg aaagctgacg
    41221 cggtttgaag ggattttcga agagtataaa attttgacat tctaaaacgc atcctatcaa
    41281 gttcactcaa acctgatagg atgcgttttt atcattttga aatctattta ccccacctca
    41341 ttccccttct tgatttcgtt taagggaaaa gtggtctgga acggggtcct tacctgtttt
    41401 cgaccaggga tgacaacgta aaatccgagc caagcccatc aatactccct taaaaccatg
    41461 tttttcaata gcctgaatca tgtagttgga acaagtcaga tcaaagcgac aagagggtgg
    41521 aaagactggt gagataaaac gttggtaaaa gcgcacaggc gctattaaaa ttcgtttcat
    41581 tatttcttag ttacagccat ggtgtgtagt tggctgattt cttttttatt aagacgacgg
    41641 gattctcctg gacggagtcc tgtcaagtct aggtgtccga aacgagtccg agacaactta
    41701 tctacttgga gaccaacagc ttcaaacatc tttttaacct gatggttacg cccttcatgg
    41761 atggtcaact gcaccacaga gcgatttttg actgggtcca ctttgagaat ttcataaaca
    41821 gctggcttgg ttttcttacc atcaatctca agaccacggg tcaaggggcg gagattgtcc
    41881 ttattggcca cacctttaac acgcgcgaca taaaccttgt caatctcatt acgagggtga
    41941 atcatctcgt ctgtaaagtc cccatcattg gtcaaaatca agacacctga tgtatcccag
    42001 tccaaacgac ccacagggta aatacgctct ttgacattgg gcaagaggtc gacaaccgtc
    42061 ttgcgaccct tatcatctgt cacactggaa atcacaccgc gtggtttgtt aagcagatag
    42121 tagacctttt cttcgttgta gataggttga ccttcaactt cgaccttgtc gcctgacttg
    42181 atagtggttg ctagttcacg caccacttgg ccgttaaccg tcaccaagcc ttgcttaatc
    42241 agctcttctg cttttctcct actggccaca cctgcgtggg caatatactt attgattctc
    42301 atcttcttct atcctttcac caaataattg gctttcttgg gcttgaatct caagctcatc
    42361 aatcactggt aattcttcta aatggtttat ccccatgtaa tctaggaaat aatccgtagt
    42421 cacatagagg ttggggcgcc ccaatacttc ctttttcccg tcttccttta tcaggtcaaa
    42481 agcctgcaac tttgccaagg ctccactcga gttaactcca cggatggcat caatttctat
    42541 ccgcgtaatc ggctgtttgt aggcaataat ggacaaggtc tcaagggcag cccgagacaa
    42601 gctctggttg ataggcgcct tagagtattc cttcaaaatc tctgcaaatt gaggcttggt
    42661 caccaatcta taagcaccac ttgtctcaat caaagccaaa ctggaatctg ggtccttttc
    42721 atacttctgg gctaattttc ctaaactttg ctggatgcct gtcggtggca gagagaggag
    42781 ttcagctaac tggcggaccc gaatcccatc ttcacccgct acaaacaaga gcgcttctat
    42841 ttttgctaaa gtactcatct ttcctctcta tcaagtctag ctttgaggca cttgactttc
    42901 ttccttcttt tccatgagat agatatctcc aaaactctcc tcttgcacga ggatcagctc
    42961 ctgggttttg attaactcta gggttgccaa aaagagggtg atgacctctt ggacattctg
    43021 ggcttccttg aacaaatcct gcaagcgcaa ttgatctcgt ccaatcaagg actctttcac
    43081 gataatcatc atgtcctcaa tcttatactc atcccgcaag atcgtcgtgt gattttgtgc
    43141 aaactcctct tttttcttgg ctaggatatt tgaaaaagcc aaaaagaggt caatggtcgt
    43201 cttgtcatgc acaagctccg catcttcgta aatcaactct gtcggcgctt tggaataata
    43261 ctgggcccgt tcttggtgct tggcttccaa gtgctcaccc aagagcttga acttgcgata
    43321 ttcttcgatt tgagagagga gatcctgctc caggtcatcc cccaagtctg tcacttctgc
    43381 taccttcgga aggagtttac gactcttaat cagcatgagc tgactagcca tgaccatgta
    43441 ctcacccgtc acttccagac gcatggcctg cagggttgag acataggcta gatactgttc
    43501 gatgacttcc gtaatgggca catcgtagat atccatctgg tacttagaaa ccagatgcaa
    43561 gagcaagtcc aggggtcctt caaaatcttt taatttaata tccattatct atatttttct
    43621 aaggtcagga ctgtttttaa tcctaatttt tttgcaattt cgtacaaatc gaccttgttt
    43681 tctatttgtc ttagaataaa ctgttcacgt aagacttgag ctgataagga tggaaaacct
    43741 ttctccttga caaaagattc taactgacga aaggcccact gacgagaata gggtttctct
    43801 cctctttcaa aaagataggt ctgccccatc aagggttcca attctgaaag caaggccgtg
    43861 ggaatggtga caatcctctg ttgggaagcc ttgctgattc gcagcacctg aaaatccaga
    43921 ttgatgtccg caaccttgat ggctaaaatc tcactgggca agagccccat ttctaggatt
    43981 aagagcgcta gcaagcggcc ctctggatgg tcgctttcct gccaaaaaga gtctaggtat
    44041 agaatctctg gcttttccgt cttcttttca gcttgtttgg ctaattccaa gcggtaaaag
    44101 ctgtccacct ctcctttttg atagagaaag tatagaaatt ggttacaggc cgaaatcttt
    44161 cgcttctggg cgctgatttt tagattggct agctgggctt ggtaaatctt gagactggtc
    44221 tcagaaatcc gctcacctac catgtctaaa aattgctcca aatcatactt ataggactgc
    44281 ttggaattga cagacaagcc ctgcttttcc tctaaaaagg ctgaaatcct gtctctcatt
    44341 ggcatcgaat ctcatattcc ttactaaagt catgcaagag ggcattaacg gccttgagga
    44401 tggacttgcg cgtaataatc ccttggaaaa taccctctgc atccacgacc ggtaagaagg
    44461 actcatctac tagcttgtgc aagacctccg taatggtgaa atcaggcgaa acaaccgcta
    44521 cgtccgtttt tgtcatatga acgatatccg tatccgccat gatttcttgg ctcaagtcat
    44581 gctccatctg ataagccata atatctctga gtccaatcgt cccaacaaac tgtttttcat
    44641 ctgtcacaac gggaacacgg gtataggtca tctgactgag caagagggtc gcatgatccg
    44701 cattgtgggt atcaatcaac acagctagat ttttagcagg ggtcaaaaaa gtttcctcct
    44761 gccccaacaa gaaagtctca aactccttgg caatcatcgg ctaaactcct tggacaaacc
    44821 tggatacacc tcgtgatctc gtgtcaaaaa gtccactttg aagtaactat catcaatctc
    44881 cacacgagca tagagacatt ctctgatggt acctcgtggt tgactgatag aacctggatt
    44941 tagaaagagg atcttgcctt ccaaccaagc acttggcaca tgcaagtgac catagaggca
    45001 gatagcggcc tcttcctcct gagcccagta gtccaacttt tgaaagttga aattgatgtc
    45061 aaacaagtga ccatgagttt ggataatctt ggtcgaacca agctcagtca ccagacgttc
    45121 tgggtagccg gcgtagaagt ccatgttccc tttaacaacg cggatgccct cccaaagtgg
    45181 agaatccgga cgtagttcag aatcgccgtt atgaaaaacg gcatcgactt tgcccacata
    45241 gcgatcacgg acttcttcca caatcaagct atcgccatgg gaatcgctca ttacaatgat
    45301 ggtttgcttt gccatgatgg aaatacctcc aaaagtttct taacggctaa ggcacggtga
    45361 gattgactat ttttttcttc tagggttaat tcagctgatg actcacctgt ctctcctaca
    45421 aggaagaggg gatcatagcc aaagccattt tcacccttag gttcaaagtt aatataacct
    45481 gaccagtctg cttcaacaac taaactttcc ttatttgggc tggctacgac tagggttgtg
    45541 tggaactgag ccgagcggtc cttgagttca aagaccatgg ccaattcgtg caagagtttg
    45601 gcattatttt cacggtcagt tgctcccaca cctgcgaaac gagctgacca gacgcctggt
    45661 aagccaccaa ggacatcgac tttgagacca gaatcatctg ccaaaaccat cttacccgtt
    45721 aattgagaaa tggtttctgc cttaaggcgg gcattttctt caaaggtcat acctgtttct
    45781 gctacttcag gcaggtcagg gtagtcatta agattttcca catcgtagcc taacttatca
    45841 aagatagctc ggaattcctt ggttttgcct tcgttacgag tcgcaatcaa caaggtttct
    45901 ctgaccttgc ttgtctcaaa gaaatcatga acattgaccc cttctttagg caattctaca
    45961 tacaagagtt gcccattttc aaccaagagc agggccccat gacgttgaat aacttccaag
    46021 tttcgtccca tttcttgatt aagcatatct accacaaagg agaacaaacg gtaggtagaa
    46081 ccatagcgta aaacagtaac tgaaagcggg aaaccatact cttcatctcc aaatattttg
    46141 gagaattcaa acagaggaaa atctgtctta tagtcgctca aactgttaac gccaccaaaa
    46201 atactataag acccaacata ccagtcctgg tcatccttat attcataaat tttatttgtc
    46261 ataattctac atgctccaca tgaatctctt tttccagcca ttcttcacca atttgtgcaa
    46321 aactttggct actggctgtt gtgtaaaaac ggtgatggag tggtccagca tcgcgaccac
    46381 gattgatttc aaaataattg agtaagactg agatatcccg tacgcactct gccccactat
    46441 cgatgagctg aacctttggc cccatcacat tttggataat agggcgaagg agtggataat
    46501 gagtacagcc caaaatcagg ctatccacct ttccaaccaa gggacgcagg gtttcataga
    46561 ccaccttctt ggtaacactg gttgacaggg cacctgactc aaccaaggga gcaaacttgg
    46621 gacaggccaa gctctccacc tgtaagtcgg gatccagatc atggattttc tgacggtata
    46681 tgtctgattg taccgtcatg ggcgttccaa tcactccgat tttcccacct tgactggact
    46741 tgatggctgc cgaagctcct ggcaaaatta cacccaagac aggaatatct agttgagcct
    46801 tgatttcttc ccagacgacc gcagtcgcag tgttacaagc aatgacaatc attttgacat
    46861 ccttggtcaa gagaaagttg accagctgcc aagtatattc acgaatttgc tcagcaggac
    46921 gggggccata gggcgcccgc gccgaatctc caatatagac gatttcttca tggggaagct
    46981 ggcgcatgag ctcgcgcaca acggtcaagc ccccgacacc cgaatccaaa aaaccaattg
    47041 gtcgattatc catacagtct tctttctagt cttttttctg attgatcgtt cattatgatt
    47101 ccttgtcctg aacgaactga ccgacagctt gatagaatgt caactacctc tctcttaatc
    47161 ataatcaaat atcaatagaa tgcaaggaaa aagtctcatc cctaaaccat aaccaacata
    47221 gtgagaagtc tggaactttc atcccagact tttccttatt tattttttct ttttattgtt
    47281 agcaagggct gccttttgtt ggcggatgat ttggtggtaa acttgttgta ccttagcttc
    47341 gcttggtttt tgaccatttg cactcaaaag agtacgaact gcttcagcat tcaaacgtgg
    47401 gttgtcagca aattcttttt cgatttgctt acgaaccaag tacattcctc caagagctcc
    47461 tcctagaaaa gctagcacaa tcaatacaat tgctaaaagt aaatccatca tttttctcct
    47521 gtttcttttt gagtcccttt cattatacca caaactagcc accctgacca gtttgttcta
    47581 cactttcagg gatggaatag acagcaaaaa gaaccctgct tttctgaaaa agaggtctcc
    47641 ttgctaagtt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cacaggttgc
    47701 tcaaagcacc gctttgaggt tgcagataaa actgacacgg tttgaagaga tttgcgaaga
    47761 gtattaattt acataaatag ccagtgtttg atagggtttg agtagaattt tctcagacac
    47821 ttctgcatct tcatagtttg atatcaaaat ctgtccattt tggtagactg ctggcaagtc
    47881 gatttccact tctttagcat aaaagttatt gagcactagt aacttttgat cctcaaactg
    47941 gcgttcaaaa gcgtagactt gtttgctatc ttcaaaggct ggtttgtaac ttccttctga
    48001 aatgattggc atttccttac gcagtcgaat caagtcttga tagaaggtaa aaatcggacc
    48061 ctggatttca ttttctacat tgatgtcttt ataggattta ccagctttca accaaggagt
    48121 gcctgttgaa aatcctgcat tttccgaagc atcccactgc atgggaatgc gtgaattatc
    48181 acgcgactta gcttgaataa tctggaaggc ttcttgctga ctctttcctt cttctaagag
    48241 catctgatag gcattaagcg attcgacatc cacataatca gccatagaat catagtctgg
    48301 gtcaatcatc ccgatttcct cacccatgta gatataaggt gtcccacgtg acaggtgaat
    48361 gctggccgct agcatggtgg ctccttcctt gcggaagttt tgaatatcga caaaacggtt
    48421 caaggcacgt ggttgatcgt gattgttcca aaagagggca ctccaaccgt ctttatcact
    48481 catttcctta ccccaactat ggtaaagact cttcaactct tcaaaatcaa agggagccaa
    48541 ggtccacttt tgtccatcct tatagtccac cttgaggtga tgaaaattaa aggtcatgga
    48601 taattcctga cgatcaggcg acgaataaag gacacagttt tccatggtgg tagaagacat
    48661 ttccccaact gtcataaagc tatcgtcaga tccaaaagtg gcttggttca tcatacgcaa
    48721 atagttatga acgatgggtt tgtctgtata agctggcttc ccttcatttt caggacagtc
    48781 cactgaaacc tcgtccttac cgatcaaatt gatcacatca aatcgaaaac ctttgacacc
    48841 cttgtcgcgc cagaaattaa caaccttgaa aagctcctta cggacattgg gattgcgcca
    48901 gttaaggtca gcctgggtct catcaaatag gtgaagatag tatttcccag tatccccgaa
    48961 aggcgcccat gcagaaccac caaacttaga ctgccaatct gttggttggt cttggatgaa
    49021 gaaaaagtct tgataatact tatcaccagc tagggctttc tgaaaccatt catgctctgt
    49081 cgaacaatga ttaagtacca tgtccagcat aaagtcaatc ttgtgctctt taccgataca
    49141 caccatttcc tcaaaatcag ccatatcacc aaaaagagga tccactgcca tataatctga
    49201 aatatcgtaa ccattatccc gttgaggact tggatagaat ggattgagcc agaccatatc
    49261 cacacctagt ttggctagat agggaatttt tccgataatc ccacggaaat ccccaatacc
    49321 gttttcagtg gtgtctttgt aagattttgg atagatttga tagactactt ttcctttatc
    49381 aagtgtcatc tgtttctcct tttctgataa aagggaggaa gcagtcttcc gtccctattt
    49441 gtgctatttc aattatactc aatgaaaatc aaagaacaaa ctaggaagct agccacaggt
    49501 tgctcaaaac actattttga ggttgcagat agagctgacg tggtttgaag agattttcga
    49561 agagtattag attcgtgtag cgaccatgag agatgctcca gcttggatcg ttgtcggata
    49621 agttccggga atagtcgctg tataagcatc ttggttggtg atgataacaa gagtttctgt
    49681 caccagacct gcagccttaa tgacatccat atcaaaacga atcagttgct ggccaactat
    49741 aacgtgatct ccttggacta caagactttc aaaacctttg ccatcaagac ctactgtatc
    49801 cataccgatg tggatgagca attcaactcc ctcgtcagag acaatgccga tggcatgctt
    49861 ggtagggaaa agaaccgtca ctgttccatt aactggagag gtcaactcac cttggcttgg
    49921 ttcaatgacc agaccttgcc ccatgacacc tgatgcaaaa acaggatccg tcgcttgact
    49981 caattctttc acttggccag ttagtgggct gataatttct accgaagtaa gttctactag
    50041 ttcatggctc acaaattctg cttcttcttg agcaacgaat tctgcctgca agttcgtatc
    50101 gccctctgtt tttgtaaaga gaccagcctt gcggaagaag aaagtcaaga gcattggaac
    50161 aacaatcgca actagcatag ttcctgcaaa tggcagcatg tattgaggtt gaatagagag
    50221 aatacctggc aaaccaccga taccaataga agccgcagtt acattaaaag taacggataa
    50281 catgcctgca agggctgaac cagtcatccc agcaacaaat ggataaatat attttacgtt
    50341 aaccccaaaa agagctggtt ctgtaacacc gagataggct gaaatggttg caggaagtga
    50401 aacctgagcc tcacgctcat catggcgatg catgaaataa taggcaaaca cggctgagcc
    50461 ttgagcaata ttagaaagag caatcatagg ccagagggca gtgccaccag catccgcaat
    50521 caattgtgta tcaatggcat tggtcatgtg gtgcagacct gtgatgacaa atggagcgta
    50581 gagggcacca aaaattgcac cgaagagcca ttttacagga cccgttaaac ctgccaatac
    50641 aactgatgaa agtccttgtc caattgtcca accgattggc cccaagacag tatgagccaa
    50701 aatcaaggct ggaatcaatg acaaaaaagg tacaaaaatc atggaaatga cttctgggat
    50761 atgtttgcgc caaaaaattt caagataaga cagactcaaa cctgcaagca aggctgggat
    50821 aacttgggct tggtaaccaa tacgattaac agtaaaataa ccaaaattcc aaacccagtt
    50881 tgctgcgata tcagctgctg gcgttgaagc aaccgcatag gcattgagca actgaggcga
    50941 taccaaacag attccgagaa caattcccaa aatttggctg gttcccatct tacgagaaac
    51001 agaccaagta atccctactg gtaagaactg gaagatagct tcaccaggca accagaggaa
    51061 gtgattaacc cctgcccaaa actgagagga ttctgtgatg gtcttgccat ccaacatcga
    51121 ccaatggaca ccttccaaga cattacggaa accgaggatc aatccaccaa caatcaaggc
    51181 tggaataatc ggagtaaaga tttccgccag agtggtcata acaccttgga ccacgttttg
    51241 attactctta gctgcagact tggctgcttc tttggaaaca ccctcaatac ctgaaacggc
    51301 tgtaaaatca ttataaaaga tgggcacgtc atttccaatg attacctgaa attgacctgc
    51361 atttgtaaag gttcctttaa cagctggaat tgactcgata gctttaacat tagccttctt
    51421 atcatctcct aaaacaaacc gcatccgtgt cgcacagtgg gtgacggcag tcacattctc
    51481 tttacctcca attgcctgaa gcaaatcttt ggcttcttgt tcaaattttc ccatttgatt
    51541 ctccttatac ttgtcaaagc aagtttgatt tgataagtat attgtaaacg ataccaaact
    51601 tgtctgcaac ttgtttggta taaaaagggt gtttttttgt aaattttcta gcacttgtat
    51661 ggtaaaatag atacaggtgt tcattaaact agactaaaaa cctatttaag aaagcaaaat
    51721 gaaaaaatac caacaattat ttaagcaaat ccaagaaacc attcaaaacg agacttacgc
    51781 tgtcggagat tttcttccta gcgagcacga ccttatggag caatatcaag tgagtcgtga
    51841 taccgtccga aaggccctgt ctctcctcca agaggaagga ttgatcaaaa agataagagg
    51901 gcaaggttct caagtcgtca aagaagaaac cgtcaatttc cctgtatcca acctaaccag
    51961 ctaccaagaa ctagttaaag aacttggact gcgctctaaa accaacgtgg tcagtctgga
    52021 caagattatt attgataaaa aatcctcact gataaccggt ttcccagagt ttcggatggt
    52081 ttggaaggtg gtccgccagc gtgtggtgga tgatctggta tccgttctgg atacggacta
    52141 tctggatatg gaactaatcc caaatctcac tcgccaaatt gctgagcagt ctatctattc
    52201 ttatatagaa aatggcctca aactccttat tgattatgct cagaaggaaa tcaccattga
    52261 ccactcaagc gaccgagaca agattctcat ggacattggc aaagaccctt atgtcgtttc
    52321 gattaaatca aaagtctatc tccaagacgg acgccaattt cagtttaccg aaagtcgcca
    52381 taagttagaa aaatttagat ttgtagattt tgcaaaacgc aagaaataaa agactgagac
    52441 accagatctc agcctttttc tttatcccaa aactaattca tcactgacca gactttggcc
    52501 actatttttc tggaagagat gcataaggtc ttcaactgtc agatgctttt tctcttctcc
    52561 cttgacatcc accactatct tgccttgata gagcataatg agacgattgc cgtactcaat
    52621 cgcatgattc atatcatggg taatcatcaa agtcgtccac tgatggtgct ccacaatctt
    52681 ttgcgtcaag tccatcacca tttgactggt tttcgggtca agtgccgcag tatgttcatc
    52741 caaaagtaaa agttttggtt tcatcagatc tgtcatgact agagtcaaag cctgtctttg
    52801 tcctcctgag agatattgag tatctacttt taagcggttt tcaagaccaa tattcaactc
    52861 cttcaaggcc tcttggaact ggattctatc cttctccttc acgccccaac caagccctct
    52921 cttctgcccg cgtctcaagg caatagccat attctcctca atcgtcaaac gagaagctgt
    52981 tcccatctta ggatcttgaa aaacacgggc aatatccttg gctctctttc tgacactcag
    53041 atttttaatg gatttccctg ccagtagaag gtccccttcg tccaccgata gattgccagc
    53101 caagatattc atcaaagtgg attttcctgc tccatttcca ccaatcacag agataaaatc
    53161 tccctcttca acctctaaat ctaatccttt gaggacatgg ttctcattga ccgtccctgc
    53221 ttcaaatgtc ttgtgaatat tttcaagtgt taacaaactt gccataactt tctcctccta
    53281 ttcatttctc aatttcagac cacgaatctt taatctcttt tgcaattctg gtgcaaataa
    53341 aaccaaagcg agcaagattg cattaaagag acgtaccaag ttttgatcta gatttggaat
    53401 ttcatagata tttaaaataa tcaaacggta aacaatagca ccgattccga tggataataa
    53461 gcggcctcca atggtcaagt cgtgtatcaa gacttccaca ataatcaccg agctcaaacc
    53521 aacaacaatg gttcctgtcc cagaagtcac atctgaaaat ccatcatttt gggcaaacaa
    53581 ggaaccacat agagcaatca aaccgtttga aatcatgtaa ccaacaatct tcatggtgtc
    53641 tacattgact ccattggcct cactcatcgg gatattatcc ccagtcgaac gcaagaccaa
    53701 gccaatctct gttttcatca aaagggtcaa gaccaaacaa acaagtaaaa aacaggccaa
    53761 actaagtgag aaaacagttc cttcatttgt cagacccaag ctcgccaact gtttaaagac
    53821 ggttgcagaa tctcccaagg aaagattggg tacactgccc atgattttaa tattgattga
    53881 atagagccct gtcaaggtca caatccctgt caagagagct gggattttca tcttggtgtg
    53941 gagcattcct gatacaagac ctgctaccat acctgccagc aaagcaagta aagtcgcaag
    54001 ccaaggattt gcccctgcct gtatctgtga tacaacgact gctgccccca gaggaaaggc
    54061 tccctcagca gtcatatccg caatatccaa aatacggaaa gtcaagtaga ccccaatcgc
    54121 cacaatcgac cacaacaaac cttctgataa actagataac acaaaattca tcttaatcct
    54181 ccttattcct tgccttctaa cttactaata tcaattccca atgcatctgc catttcttga
    54241 ttagtatgca attccagttt ttcaggcaac tcaactgcta tattttctgg tttctcacct
    54301 tttaaaacat gaatcagcat gcgagctgtc tgtcttccca attcttcata attggttccg
    54361 tagttataca agccaccaac agcaatcatt tctgttgaac caccgaatac tggaaccttg
    54421 tgtttaatag aaacctgctt aactgtttcc atggttaacg aaatgatatt atcagttggg
    54481 acaaaaacca tatccacctc tgccatcaaa ctctctgctg ccgccttgac gttattactg
    54541 tccaagattg ttttttcaac aacggtaaag cctttttctt tcagaagtcg cttagcttca
    54601 tccttttgaa caaccgaatt gggctcgctc tgagcagaag gccttgcgat ggctagaacg
    54661 acatcgctgg attctgctag ttgctgggaa atcgttttta gatttctttg ttctccctgt
    54721 gcattttgca aatcaatctc aatattttcc ccctcaacat agccttgttt ggccagctca
    54781 tccacaaatc cttctctagt agcgtctaag gactggtggg taataaactg cgaaataccg
    54841 atacgaaaga catctctttt cttatctgcc ttcaactgat gcaaactgat cagagaagtc
    54901 aagaggatcc ccactaccaa gagggggcta gtgattttcg aacaactttc ataatgaaac
    54961 tccttctcag aaaagataaa acaaaaaacc gcctagatac tatctaaacg gatacttgaa
    55021 ataacctaac aagttacaac ttagctagtc catttagata ttcatctata tggaccacaa
    55081 tcaaaaatct tagccacata gatacaaaca aattgcttga actgtttgca tccatggtga
    55141 catgtctaca aacactatct aaagtagcta aagtaaaagt tttgattcat agttacggct
    55201 tgtctcttat tcatttcttt ttctgctttc ttttttgatg cttcctgtcc taccaccttt
    55261 ttcatcacct gtcaataaca tttcataatt tttaaaattt ttcaaaaatt ctttcaggaa
    55321 gctttcaaag tttttcaaat cagtccaaca aaaaaagttt tataatttcc ataaaaattg
    55381 acatggaaat tataaaacca ttactagttt agtccttttt gataacgtgc caattcggct
    55441 tggttcgccc aaacatagtg acctggacgg atttctacca tagatggctt atcagtctca
    55501 tagtcgtgtt gacttgggtc gtaaaccttc aagaccttct tacgttccaa gattggatct
    55561 gggattggta ccgctgaaag caaggcttga gtatatgggt gaattggatt gttaaacaat
    55621 tcttctgttt ctgcaacctc tacaataaca cccttgtaaa taactgcgat acgatctgaa
    55681 ataaagcgaa caaccgacaa gtcatgggcg atgaagagat aggtcaggcc gagctctttt
    55741 tggaattttt tgagcaagtt caagacttgg gcacgtacag aaacgtccaa ggctgaaatt
    55801 ggctcatctg caataacaaa gtctggttgc atgaccaagg cacgggcaat accgatacgt
    55861 tgacgttgac cgcctgagaa ttcatgaggg taacgagtca agtgctcagc aagaagacct
    55921 acttcacgga taatattttg aactttctct ttacgttctt cttcatcctt aaataaacgg
    55981 tgattgtaaa gaccttcaga aataatataa tcaacagtcg cacgttcatt caaacttgcg
    56041 gcagggtctt ggaaaatcat ctggattcga cgaatcaatt ccgcagcttg ttcacgcgat
    56101 ttcttaccat taatcttttg accatcaaaa atgatatctc cattacttgt atcatttaga
    56161 ccgatgatag cacgaccaat agttgttttc ccactaccgg actcacctac aagcgagaaa
    56221 gtttctccct tgttgataaa gaagttagca tttttaaccg cgacaaactt cttacttcct
    56281 tcaccgaagg aaatttctaa atctttgatt tctactaatt tttcagacat ttccttcctc
    56341 ctagtcagcc agatgggcaa atcccatttt ttcacggatc ttatcatgga gatttgcaat
    56401 cacagctggt ttttctactt ttggagcatc ctcatgaaga agccaagttt tagcccaatg
    56461 tgtctctgat actgagaatt gaggagcttt ttgttcgaag tcaatctgca ttgcgtagtc
    56521 agaacgcaag gcaaaagcat cccctttcag gtcagtataa agtgacggag gtgttcctgg
    56581 gattgagtaa agttcccctt tatcatcagc aagctgaggc aagctagaca agagactcca
    56641 tgtatatgga tggcgagggt catagaagac ttcctcaacc gttccatact caacgatttc
    56701 tcctgcatac ataaccgcta ccttatccgc aatacttgcc accacaccaa ggtcgtgggt
    56761 aataaagatt gttgtgaaat gatactcgtt ttgtaaagat tttagcaaat caataatctg
    56821 agcttgaata gtcacatcca aggcagttgt tggctcatca cagatcaaga catcaggtcg
    56881 gcaggcaagg gcaatcgcaa taacgatacg ttgacgcatt cctccagaat attggaatgg
    56941 gtattcatta aaacgtctat ctgcgtctgg aatgccaacc ttattcatgt agtcaatggc
    57001 caattctttc gcttctttag ctgtttttcc ttggtgtttt acaataactt ctgtaatctg
    57061 actaccaatt gttttaatgg ggtccaaact agtcattggg tcctggaaga tagtcgcaat
    57121 cttagcacca cgaatttgtt cccaatcctt gtgagaagat aaagctgtca agtcctgacc
    57181 acggtagtca atactacctt gggcaatacg accattttct tcgagcatac ctgtgaaggt
    57241 ctttgtcaaa acagatttac ctgatcctga ctcacctacc aaggctaata cttctccttc
    57301 gactagttca agggaaacgc cgcgaatggc tgtcaatact ttgtcacgaa cgtcaaattc
    57361 cacgacaata tcgcgagcag tcaaaattac atttttttct tttgtcattt ctactcctat
    57421 ctatgtgtac gtggatcact agcatccgct aagttttgac caactacgaa aagggacaag
    57481 gataccaaga caagggttgt caatggaatc cagaacaagt aagcattggt tgttacgttt
    57541 tgtgaataat ccgaaatcaa acgacccaaa cttggcactg taatcggtaa tccaagaccg
    57601 aagaaagaca agaaggcttc gtatgagata aagcttggaa gcatttgagt catggttgtc
    57661 acaataacag ataccaattg aggcatgata tttttggcaa caatcttcaa ggttggtgtt
    57721 cccaaagtac gtgacgccaa gttgtattcc aagtcacgat agcgcaagat ttgcacacgg
    57781 atcatgaagg caataccaat ccatgttgtt acgctcatgg caaaaatcag attccagaat
    57841 ccagctccga ttgagtaagt taagacaata acaatcaaaa gaggtgggat gtttgagatg
    57901 acgttgtaaa cttccatcat gacacggtca actgattttg aaatacccca aataccaccg
    57961 acaaaaacac cgataaccaa gttaatcact gtcgcaatca cagaaatgag gatggagtta
    58021 cgagctccga accagacacc gtcaaagagc gatttaccgt tactgtcagt accgaaccaa
    58081 tgctccgcat ttggcttgat ataacgaaca ctaaagtcgt ttaccttgct gacatcattg
    58141 aaatcaaact tagaaaacat tgggtagatg aaacttatca aaatgatggc taccaagatt
    58201 cccaacatga ctacagttga ttttttcttc ataaattgtt taaacactga tttccagtaa
    58261 gaatatgctg gcgcatcaat agtttcagag gcaaaatcgt cacgttttac aaactgaaat
    58321 ttttctttat cgattgtaga cattatttgc ctcctttctc agtcaattta atacgtgggt
    58381 caataatagt catccaaata tctcccaaaa gacgtgagaa gatagaaata catgtaaaga
    58441 tgaagacaag accaacgacc atagagttat tagatgcttt tacagagtca atcaacattt
    58501 tacccatacc tgggaaggcg aagactgttt cagtaagggt tgcaccaccg ataaccccaa
    58561 taatggcacc aggaattcct gaaaccagcg gaaccatggc atttttaaag atgtgtttgt
    58621 ttgaaatttc tttttcagac aaaccttttg cacgagcgaa acgaacaaag tcttgagatt
    58681 gcaagtcaat catgtaacga cgaatccaaa tggctgtacc aggagcaccc aacaaaccaa
    58741 ggatgactgc tggtaaaacg taagaacgcc aatctccagc tcccaagata gggaatgaat
    58801 ctggaaggga aatagatgat ccaatcaatc gaacgatgta aaccaaggca atcgttggaa
    58861 gagcaagcaa gaaggtcaaa gcccctgttg agaggctatc aatccaagtg ttcttgaaac
    58921 gagccatggc tgaaccaagt ggcacggcaa gagcataggc aagaaccaaa ccaatcaaac
    58981 cagtaatagc agagctgaca atcatagatg gatattggta attactttca gtcgctgtat
    59041 aaggatcatc tttcccatag ctagctactt cacgagagtc agcctgacta ggtgacttgt
    59101 aggttcttga gtaaatattt acagaagacg ttttcttacc tgttgggaac tgaacttggg
    59161 cagttttggt ttgtccttga ccttgagtaa taacctgaag aactggtgta ttagcatagg
    59221 ttgggtaaga gtcacctaaa ttcaagttca caaagttttg atgaacaaat gggaactgac
    59281 tgttaaagta caagagatat ttatgtttag ttcctgaacc gaccaatgac catccgatag
    59341 ctggatcatt ttcaaaacga aggtagcgtt tcaagtctgg attttcaggg tcttggattt
    59401 tatttgtatg gtcaatgtca atcaagttag catagaagtg aaaaacacgt tcaaaaattg
    59461 gaatttcacg agtagcatag aattgaccac tttcagtaaa ttctcccaaa gtccaaccat
    59521 gacctaattg attgatgtac ttttcataaa tagctttatt ggtcgcattt gcttctactg
    59581 ttacagaaga atccatgcta cttgcctttt cttgcaactc tttagtatcg taatactcaa
    59641 tgtagcccat acgctcaaac acagtatttt catagttatc acgtttatca gccgttgtcg
    59701 caattttatt atagttagga tcctgcttga aaatcaattt tcgaggaacc aaggtataga
    59761 taatcgtgta ggtcaaagtc gttactaaga aaatcgaaac caatgaccgc aaaacacgca
    59821 taaaaatata ttttttcata ttatttcctt taaaaatccc aaaagaacct tctcctcatg
    59881 gagagaaagt tctattagaa attatttact tcacatgact tgccaattct ttttgagctt
    59941 tctcatttga ttcagctttt tctttcaacc atttttcacg agctttttca tactcttcct
    60001 tagtcaccgc tttatcttgt aatttcaaat atttgaagta aacatctgac cccttagagc
    60061 ctgtttgcgc agaagctcca gtaaatggaa caattcgtga aagcactggt gctgcaccag
    60121 aagaagccat agcaggaata aagagtgaac tatctgtcaa ccatgcttga gccgctgcat
    60181 atttttcata acggacattc aagtcgcttg tctctttggc agcttcatca actaatttat
    60241 cgtattcttt caaaccaact tgaactactg aagggctatt tggattatca aatcctaaat
    60301 atgtttttgt agtttcactg ctagttgttt ttaaaatatc caggtaagta gatgggtctt
    60361 gatagtctgg cccccatgaa actcctcccg atacatccca atcctcagat gaagcattgg
    60421 cagcatagta agtaatatta aggaattcat cacttgtcat ttgttgaata tcaacaacga
    60481 cattttcaac accaagaact gtttctacag attgtttaaa ggactgaata cgagatatat
    60541 agttttttga tgcttggtct actggaacgt ccagatgaat aggaaactga acgccgtctg
    60601 cttctaaagc tttcttagct ttcgcaaact ctgccttggc cttgtcagca ttgaataaac
    60661 catcctgccc atcagctaaa ttcacacctt tccactcatc accataagca ggaagttgag
    60721 cagcgactaa atcaccaaag gtcttctcac cagctgaaac aaagtctggt tttacaaata
    60781 aattacgaac tgctaaagct gctccatctt taccattgat ttgagctgag taaactgagc
    60841 gatcaagagc aaaattcaag gcttgacgga aatctttgtt aagcaatgcc ttcttagtag
    60901 ctactttctc tgaatctgta gttttagaag tatagttgta actttggcga tcaatattca
    60961 cacccagacc agcaatccca gagcctgatt gtgtgtaata gatattgtcc ttgtattctt
    61021 ctgcaacctt agaatagttg gagctggtag ggtaaagacg ggcataacta taggctccac
    61081 tagtgaagtt acgctctagc gactcctgat ctgatccatc atagtaagct agattgatag
    61141 tatctaggtg gacattttct ttatcccaat attgctcatt ttttacaaac tctacagaag
    61201 attttgcagt caaccctttc aacaagaatg gaccattata aagcaaggat gtcggatctg
    61261 ttggtttagc aaaatcgctt ccttttgatg tttcgaattc ttcattcaga ggccagaaaa
    61321 tagaataggt caacttagag ttccagaacg gttcaggctg gttcaaagtg tattgtaacg
    61381 tataatcatc aaccgccttg acaccaactg ttgaaaaatc tgttgaagtt cctgatagat
    61441 aatctgccaa gcctttaacc gaattttcag ctaaatacat agcttctgat tttttatctg
    61501 ctgcgtgttt taaaccgttc acgaaatctt tagccgtcac ctctgcatat tcttctccat
    61561 cagaggtaaa ccatttaacc cctttacgaa tcttataagt gtaggtcaaa ccatccttag
    61621 agacttccca atcctctgca actgcaggag caagattacc gtaattatcg ttagtgaata
    61681 aaccatcaat cccatttgaa gtcactactg ttgtactatt tttacttgaa atcaggtagt
    61741 ccaaggtttc tgggtctgct gtataaacat agccataagc tttaggggct gatgaatcag
    61801 atgattttga agaactgcat gctgcaagta cacctgctgc taataaaaca agacctgctg
    61861 tagcaaatac acgatttttt ttcattttct actcctctgt ttatgtgaat tatagattga
    61921 caaccattat atcacattat ccattaaaaa tcaaacaaat tttcagaata tttaggcttg
    61981 ttggcacaaa tttttcattt tttttgaata tatgattcaa attgtcgttc gaagtgtcaa
    62041 agactacagt gaaaatagga aatttgacgc agaaactttg gagcttagga agacatacag
    62101 taaaatgaaa tacggacgga acaatgtgat tttggaattc aaattaaatt ataacaatat
    62161 tgtagaagta tcattctagt attcaagatt cagtttacta tgtcttttca caccaacctt
    62221 attccgaatt caattacttt cgtgatttac acatatagat taagactatc ttttacccaa
    62281 atcattcata cctctctcaa ctagatgtaa cttacaaaac ccctgacctc atgagccact
    62341 ttcttcctcc tcatgaggtc agttttactt tctgctgttc cagtatcgtt tttcctcgct
    62401 agatttcctc aaaagggcag actcctccct tggtgcgtca cacgattttt tcatctcgac
    62461 tgttctttaa tgcatcatta acgacgcttt tcttccaggt ggttcataag gaacaggaag
    62521 attcaggttg acttttctaa tcctagaata aagtgctgaa aacaattcgg aataggcata
    62581 gagactagac aatttgagga gctgcttgcg tcctgttcga acacagtttc ctaccacgtg
    62641 aagaaaaaga tggtggaagc gtttgattgt taaagtttgg aagtcacctc cagctagatg
    62701 tttgagaaaa agatagagat tgtaggcgat acagctcatc atcatacgaa cttcgttttt
    62761 gattaaggtt gaactatccg ttttatcgcc aaaaaatccc tccttcatct ccttgatgaa
    62821 attctcggct tgaccacgtc cacgataaag ctgaaactgg tcttggcttg ttccactcgt
    62881 catatttgta acgagagaaa taatatcgta g
//
LOCUS       DAVLTG010000006        59990 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLTG010000006 DAVLTG010000000
VERSION     DAVLTG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.006"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..289
                     /locus_tag="VYN12_000396"
     CDS             <1..289
                     /locus_tag="VYN12_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1414839.1"
                     /translation="EVKPQPEKPKPEVKPQLEKPKPDNSKPQADDKKPSTTNNLSKDK
                     QPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAKKRMK"
     gene            complement(508..1488)
                     /gene="dusB"
                     /locus_tag="VYN12_000397"
     CDS             complement(508..1488)
                     /gene="dusB"
                     /locus_tag="VYN12_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1414840.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWANPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(1475..2347)
                     /gene="hslO"
                     /locus_tag="VYN12_000398"
     CDS             complement(1475..2347)
                     /gene="hslO"
                     /locus_tag="VYN12_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1414841.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2512..3939
                     /locus_tag="VYN12_000399"
     CDS             2512..3939
                     /locus_tag="VYN12_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1414842.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4098..5606
                     /gene="glpK"
                     /locus_tag="VYN12_000400"
     CDS             4098..5606
                     /gene="glpK"
                     /locus_tag="VYN12_000400"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1414843.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5648..7474
                     /gene="glpO"
                     /locus_tag="VYN12_000401"
     CDS             5648..7474
                     /gene="glpO"
                     /locus_tag="VYN12_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1414844.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            7542..8246
                     /locus_tag="VYN12_000402"
     CDS             7542..8246
                     /locus_tag="VYN12_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1414845.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8543..8746
                     /locus_tag="VYN12_000403"
     CDS             8543..8746
                     /locus_tag="VYN12_000403"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414846.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8833..9420)
                     /locus_tag="VYN12_000404"
     CDS             complement(8833..9420)
                     /locus_tag="VYN12_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414847.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10522..11799
                     /gene="ltrA"
                     /locus_tag="VYN12_000405"
     CDS             10522..11799
                     /gene="ltrA"
                     /locus_tag="VYN12_000405"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV1414848.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLPTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            12256..13434
                     /locus_tag="VYN12_000406"
     CDS             12256..13434
                     /locus_tag="VYN12_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1414849.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRSALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13748..13879
                     /locus_tag="VYN12_000407"
     CDS             13748..13879
                     /locus_tag="VYN12_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1414850.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13900..15450
                     /gene="dltA"
                     /locus_tag="VYN12_000408"
     CDS             13900..15450
                     /gene="dltA"
                     /locus_tag="VYN12_000408"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1414851.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWISTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15447..16691
                     /gene="dltB"
                     /locus_tag="VYN12_000409"
     CDS             15447..16691
                     /gene="dltB"
                     /locus_tag="VYN12_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1414852.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16705..16944
                     /gene="dltC"
                     /locus_tag="VYN12_000410"
     CDS             16705..16944
                     /gene="dltC"
                     /locus_tag="VYN12_000410"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1414853.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16937..18205
                     /gene="dltD"
                     /locus_tag="VYN12_000411"
     CDS             16937..18205
                     /gene="dltD"
                     /locus_tag="VYN12_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1414854.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18360..18800
                     /gene="adcR"
                     /locus_tag="VYN12_000412"
     CDS             18360..18800
                     /gene="adcR"
                     /locus_tag="VYN12_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1414855.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18800..19504
                     /locus_tag="VYN12_000413"
     CDS             18800..19504
                     /locus_tag="VYN12_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1414856.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19497..20303
                     /locus_tag="VYN12_000414"
     CDS             19497..20303
                     /locus_tag="VYN12_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1414857.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20313..21818
                     /gene="adcA"
                     /locus_tag="VYN12_000415"
     CDS             20313..21818
                     /gene="adcA"
                     /locus_tag="VYN12_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1414858.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEERDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22980..23753)
                     /locus_tag="VYN12_000416"
     CDS             complement(22980..23753)
                     /locus_tag="VYN12_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1414859.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23929..25332
                     /locus_tag="VYN12_000417"
     CDS             23929..25332
                     /locus_tag="VYN12_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1414860.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEDSLFISSGTWSLVGVELSSPILSTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETGEWTDGQLFKIVYESLAETYKETIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25447..26085
                     /locus_tag="VYN12_000418"
     CDS             25447..26085
                     /locus_tag="VYN12_000418"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1414861.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            26097..26537
                     /locus_tag="VYN12_000419"
     CDS             26097..26537
                     /locus_tag="VYN12_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1414862.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26530..26961
                     /locus_tag="VYN12_000420"
     CDS             26530..26961
                     /locus_tag="VYN12_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1414863.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26952..27422
                     /locus_tag="VYN12_000421"
     CDS             26952..27422
                     /locus_tag="VYN12_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1414864.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27447..28220
                     /locus_tag="VYN12_000422"
     CDS             27447..28220
                     /locus_tag="VYN12_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1414865.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28217..29017
                     /locus_tag="VYN12_000423"
     CDS             28217..29017
                     /locus_tag="VYN12_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1414866.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            29076..31370
                     /locus_tag="VYN12_000424"
     CDS             29076..31370
                     /locus_tag="VYN12_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1414867.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNLIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31380..34496
                     /locus_tag="VYN12_000425"
     CDS             31380..34496
                     /locus_tag="VYN12_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1414868.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34553..36319
                     /locus_tag="VYN12_000426"
     CDS             34553..36319
                     /locus_tag="VYN12_000426"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1414869.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36465..37616
                     /locus_tag="VYN12_000427"
     CDS             36465..37616
                     /locus_tag="VYN12_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1414870.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFRDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37761..38645
                     /locus_tag="VYN12_000428"
     CDS             37761..38645
                     /locus_tag="VYN12_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1414871.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            39043..39294
                     /locus_tag="VYN12_000429"
     CDS             39043..39294
                     /locus_tag="VYN12_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1414872.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            39282..39572
                     /locus_tag="VYN12_000430"
                     /pseudo
     CDS             39282..39572
                     /locus_tag="VYN12_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39978..41309)
                     /locus_tag="VYN12_000431"
     CDS             complement(39978..41309)
                     /locus_tag="VYN12_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1414873.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAIYRLAT"
     gene            complement(41331..42842)
                     /locus_tag="VYN12_000432"
     CDS             complement(41331..42842)
                     /locus_tag="VYN12_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1414874.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(43053..44000)
                     /gene="arcC"
                     /locus_tag="VYN12_000433"
     CDS             complement(43053..44000)
                     /gene="arcC"
                     /locus_tag="VYN12_000433"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1414875.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(44165..45181)
                     /gene="argF"
                     /locus_tag="VYN12_000434"
     CDS             complement(44165..45181)
                     /gene="argF"
                     /locus_tag="VYN12_000434"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1414876.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(45239..46468)
                     /gene="arcA"
                     /locus_tag="VYN12_000435"
     CDS             complement(45239..46468)
                     /gene="arcA"
                     /locus_tag="VYN12_000435"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1414877.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            47223..48902
                     /locus_tag="VYN12_000436"
     CDS             47223..48902
                     /locus_tag="VYN12_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1414878.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GSALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFSRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGEALHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48942..51026)
                     /locus_tag="VYN12_000437"
     CDS             complement(48942..51026)
                     /locus_tag="VYN12_000437"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1414879.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQERGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            51197..52477
                     /locus_tag="VYN12_000438"
     CDS             51197..52477
                     /locus_tag="VYN12_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1414880.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSESIIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52568..55213
                     /locus_tag="VYN12_000439"
     CDS             52568..55213
                     /locus_tag="VYN12_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1414881.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLSRQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            55297..56166
                     /locus_tag="VYN12_000440"
     CDS             55297..56166
                     /locus_tag="VYN12_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1414882.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            56160..58040
                     /locus_tag="VYN12_000441"
     CDS             56160..58040
                     /locus_tag="VYN12_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1414883.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIVGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGSETAQFSILSSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58418..58780
                     /locus_tag="VYN12_000442"
     CDS             58418..58780
                     /locus_tag="VYN12_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414884.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSLEQYPDYDGFDYEEW"
     gene            complement(58850..59314)
                     /locus_tag="VYN12_000443"
     CDS             complement(58850..59314)
                     /locus_tag="VYN12_000443"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1414885.1"
                     /translation="MRRKYKSIALKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIT
                     VNYCHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQIPRKSSKLKPLTVEDKTY
                     NHALSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(59655..59831)
                     /locus_tag="VYN12_000444"
                     /pseudo
     CDS             complement(59655..59831)
                     /locus_tag="VYN12_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
BASE COUNT        18100 a        11007 c        13134 g        17749 t
ORIGIN      
        1 agaggttaaa ccgcagccgg aaaaaccaaa accagaggtt aaaccgcagc tggaaaaacc
       61 aaaaccagat aatagcaagc cacaagcaga tgataagaag ccatcaacta caaataattt
      121 aagcaaggac aagcaacctt ctaaccaagc ttcaacaaac gaaaaagcaa caaataaacc
      181 gaagaagtca ttgccatcaa ctggatctat ttcaaatcta gcacttgaaa ttgcaggtct
      241 tcttaccttg gcgggggcaa ccattcttgc taagaaaaga atgaaatagt gattgattca
      301 ttcaaaaatg tttgtaaaaa gtattcggct taaaagaaaa gagtctggga taaaaagatt
      361 ttgattttag gaattcttta ttataaattt ttaaaatcga tagattagac aaaaaagcga
      421 acaagacaga attctgagtg tcagataact gattttgttc gctttttata tttaatatta
      481 tacttttgtc ctaggctctt ttttgcatta tactttttct aattgcaaga gggcttcaat
      541 ctctgctagg gtgctagctt gcgaaatggc tccacggagt ttggcagcgc cagatgttcc
      601 acggagatag tgaggagcga ggccgcggaa ttcacgaact gcgacgtttt ctcctttgag
      661 gttaatcaat cgtttcaagt gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc
      721 aggtaggatt tctcctgttt caaagtaatg gttgatttgg ttgaagaggt aaggatttcc
      781 catggcagct cggccaatca tgactgcgtc agcaccaact tcttcgatgc gttgcttggc
      841 ttcttggaca gtacggatat caccgttggc gatgaatgga atcttggtta gagcttgggc
      901 aaccttgtaa agggtctcaa ggtctgcgtg gccagtatac atttgttcac gggtacggcc
      961 atgcatggcg agggcagaaa cacctgcagc ctcagcagcg agagcatttt ctactgccag
     1021 agatgggttc gcccagccgg tacgcatttt gacagtaagt gggatatcaa ggacagactg
     1081 gaccttgttg atgatagagt agatcttgtc aggatccttg agccacatag caccagcttc
     1141 gttcttcacg attttgttga cagggcagcc catgttgata tcgacgatat cggtcttggt
     1201 gttttcttgg atgaattctg ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg
     1261 gatagagaca gggttttcgc cctcatcgat atgaagcatg tgcagggttt tttcgttgtt
     1321 gtattggatt cccttgtcag agaccatttc cattacaacg agtccagctc cgagctcttt
     1381 tgcgatggta cgaaaggctg agttggtcac gccagccata ggcgctaaaa cggtacgatt
     1441 gggaatctca acattgccaa tcataaaagg tgtattaaga tttgtcacga atgagttcct
     1501 ccaggtcctt ttcatcaaag ttgtaagtag tttggcagaa ttgacaagtg atttctaccc
     1561 cgtggtcttc ctctttcatt tcctgtaagt ctgagcttgg aaggctggca agagcgttca
     1621 taaagcgttc atggctacag tcacattgga aacggatttc ttcttcagaa agacgcttgt
     1681 aggcttcgtc cccgtagata gccttgagga gggcttcgat atggtcgtcg ctttcgagaa
     1741 gagtagagat agctggcatt tcttggatgc gtttttcaaa gcgagcaatc tcttctttct
     1801 tggctcctgg caagacttga actaggaaac cacctgcaac cttgaccttg tcttcctcgt
     1861 ccaaaaggac attgaggccg accgctgaag gcgtttgttg gctttcagta aggtaaaagg
     1921 caaggtcttc accgatttct ccagagatga ggggagttat agagttgtaa ggatttccag
     1981 taccgtagtc tgtgataacg aggaattgac catttccaac aaaaggtccg actaggactt
     2041 caccagtcgc agtctttttg atgtcaacac caggattttg aacgtagcct ttgacgttcc
     2101 ccttggtatc agcgacggtg ataatagcac ctagagagct agagcccaac accttaactg
     2161 taagtttggt atttcctttt tcattggctg cgagaatctg gctagcgata agagttcgac
     2221 caagcgctac agttgagcta gcttgggttt gatgtttttc ttgagcagtg cggacggttt
     2281 ccgtgctatc aaggacaaaa gcacgaaagg ctccgctttc tgatatagtt ttaataattt
     2341 tatccatagc tactatttta gcataaaaat gcccaaaggg ggagccgtgt gtttactgat
     2401 tttcaggata atggaccagg aaatcagcat gaaaataaaa agagaaacag attattttag
     2461 catttgtaag atttatgcta tgcttaaggt agaaaatgaa aggggtaaca aatgtattta
     2521 ggagatttga tggagaaagc cgagtgtggt caattttcaa tcctttcctt tctattacaa
     2581 gagtctcaga cgaccgtcaa ggctgtaatg gaagaaacag gattttcaaa agcaacccta
     2641 accaaatatg tcaccctgct caatgacaag gctttggata gtggcttaga gctggctatt
     2701 cactcagaag atgaaaatct gcgtctgtct atcggtgcag ctaccaaggg gagagatatt
     2761 cggagcttgt ttttggagag tgctgttaaa taccagattt tggtttatct tctctaccac
     2821 caacagtttt tagcccatca gctggctcaa gaattggtga ttagcgaggc tacgcttggt
     2881 cgtcacttgg ctggtttaaa tcagattttg tcagaatttg atttatccat ccaaaatgga
     2941 cgttggcgag gtccagagca tcagattcgc tatttctatt tctgtctttt ccgaaaggtc
     3001 tggtcgagtc aggaatggga aggtcacatg cagaaaccag agagaaaaca ggagattgcc
     3061 aatttagagg aaatctgcgg tgcaagtttg tctgtggggc agaaattgga cttggttctc
     3121 tgggctcaca tcagtcaaca acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa
     3181 gagaaaatgc gagggtattt tgacaatatt ttctaccttc gtttgctgag aaaggttccg
     3241 tccttttttg ctgggcaaca tattccacta ggagttgagg atggtgagat gatgatattc
     3301 ttctcttttc tcctatctca tcgcattctt cctcttcata ctatggagta tattcttggt
     3361 tttggagggc agttggcaga tttactgacg caattgattc aagaaatgaa gaaggaggaa
     3421 ctattggggg attatacaga ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa
     3481 gtctatctct ataagggcta tattttacag gatcgctaca agtaccagtt agagaatcgt
     3541 catccatatt tactgatgga acatgatttt aaagagacag cagaggagat ttttcatgct
     3601 ctacctactt ttcaacaggg gacagattta gataagaaga ttctctggga atggctccag
     3661 ttaatcgaat atatggctga aaacggtggc cagcatatgc ggattggtct ggatttgaca
     3721 tctggttttc ttgtcttttc aaggatggca gccattttga aacggtattt ggaatacaat
     3781 cgttttatta ccattgaagc ttatgaccct agtcggcatt atgatttgct ggttaccaat
     3841 aacccgattc ataagaagga acagacacca gtctattatt taaaaaatga cttggatatg
     3901 gaggatttgg cagggattcg tcagttatta ttcacttaaa aggcttggtt gttccaggtc
     3961 ttttttgtga aattcacaca atctcctcac atttttttaa aaattaaaaa aagttgataa
     4021 acaagaaagc gctttatttt gtatactagt aagtgtaaag aggaaacacc tcaagatttt
     4081 tatcaggagg acagaacatg tcacaagaaa aatacatcat ggccattgac cagggaacta
     4141 caagttctcg tgccatcatt ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag
     4201 agtttaccca gattttccct caggcaggtt gggttgagca caatgccaat gaaatttgga
     4261 actctgttca gtcagttatt gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa
     4321 tcgaggcaat cgggattacc aaccaacgtg aaacaacggt tgtctgggat aagaaaacag
     4381 gacttcctat ctacaatgct atcgtttggc agtcacgcca gacagcacct ttggctgagc
     4441 aactaaaaag ccaaggttat gtggaaaaat tccatgaaaa gactggtttg attattgatg
     4501 cttacttctc tgctaccaag gttcgttgga ttttggatca tgtagaaggt gctcaagagc
     4561 gagcagaaaa aggggaattg ctctttggta ctatcgatac ttggttggtt tggaaattga
     4621 ctgacggtgc ggctcacgtg actgactact caaatgcagc tcgtaccatg ctttataaca
     4681 ttaaagaact caaatgggat gatgagattt tggaaatcct taacattccg aaggctatac
     4741 ttccagaagt tcgttctaac tccgaaatct acggcaagac agctccattc catttctacg
     4801 gtggagaggt gccaatctca ggtatggctg gggaccaaca agcagccctc tttggacagt
     4861 tggcttttga gccaggtatg gttaagaata cttatggaac aggctctttc atcatcatga
     4921 atactgggga agagatgcag ttgtctgaaa acaacctctt gacaaccatt ggttacggaa
     4981 tcaacggtaa ggtttattat gccttggaag gttctatatt catcgcagga agtgctattc
     5041 agtggcttcg tgacggtctt cgcatggttg aaaattcacc agaatctgaa aaatacgctc
     5101 gtgattctca caacaacgat gaagtttatg tcgttccagc ctttacaggt ctaggcgctc
     5161 catactggaa ccaaaatgct cgtggttccg tctttggttt gactcgtgga acaagcaaag
     5221 aagactttat caaggcgact ttgcaatcta ttgcttatca agtgcgtgac atcatcgaca
     5281 ccatgcaagt ggatactcag accgccattc aagtactgaa ggtggatggt ggtgcagcca
     5341 tgaacaactt cctcatgcag ttccaggcgg atattttagg cattgacatt gcacgtgcta
     5401 aaaacttgga aacaacagct ctaggagcgg ccttcctagc aggtttgtca gtagggtact
     5461 ggaaagactt ggacgagttg aaactcttga acgagacagg agaactcttt gagccatcta
     5521 tgaacgaatc tcgcaaggaa caactctaca agggctggaa gaaggctgtg aaagcaactc
     5581 aagtctttgc ggaagtagac gactaatact ggcagaataa agcgatttat ttagaaagtg
     5641 tgtaaatatg gaattttcaa agaaaacacg tgaattgtca attaaaaaaa tgcaggaacg
     5701 caccctggac ctcttgatta tcggtggagg aatcacagga gctggtgtag ccttgcaggc
     5761 ggcagctagc ggtcttgaga ctggtttgat tgaaatgcaa gactttgcag aaggaacatc
     5821 tagtcgttca acaaaattgg ttcacggagg acttcgttac ctcaaacaat ttgacgtaga
     5881 agtggtctca gatacggttt ctgaacgtgc agtggttcaa caaatcgctc cacacattcc
     5941 aaaaccagac ccaatgctct taccagttta cgatgaagat ggagcgacct ttagcctctt
     6001 ccgtctcaaa gtagccatgg acttgtacga ccttttagca ggtgtgagca acacgccagc
     6061 tgctaacaag gttttgagca aggatcaagt cttggaacgc cagccaaact tgaagaagga
     6121 aggcttggta ggaggtggag tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat
     6181 tgaaaacatc aaacgtgcca accaagacgg tgccctcatt gccaaccacg tgaaggcaga
     6241 aggcttcctc tttgacgaaa gtggcaagat tacaggtgtt gtagctcgtg atctcttgac
     6301 agaccaagta tttgaaatca aggcccgtct ggttattaat acaacaggtc cttggagtga
     6361 taaagtacgt aatttgtcta ataagggaac gcaattctca caaatgcgcc caactaaggg
     6421 agttcacttg gtagtggatt caagtaaaat caaggtttca cagccagttt acttcgacac
     6481 aggtttgggt gacggtcgta tggtctttgt tctcccacgt gaaaacaaga cttactttgg
     6541 tacaactgat acagactaca caggtgattt ggagcatcca aaagtaactc aagaagatgt
     6601 agattatcta cttggcattg tcaacaaccg cttcccagaa tccaacatca ccattgatga
     6661 tatcgaaagc agctgggcag gtcttcgtcc attgattgca gggaacagtg cctctgacta
     6721 taatggtgga aataacggta ccatcagtga tgaaagcttt gacaacttga ttgcgactgt
     6781 tgaatcttat ctctccaaag aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct
     6841 tgaaagtagc acatctgaga aacatttgga tccatctgca gtttctcgtg ggtctagctt
     6901 ggaccgtgat gacaatggtc ttttgactct tgctggtggt aaaatcacag actaccgtaa
     6961 gatggctgaa ggagctatgg agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag
     7021 ctttaaattg atcaattcta aaacttaccc tgtttcaggt ggagaattga acccagcaaa
     7081 tgtggattca gaaatcgaag cctttgcgca acttggagtt tcacgtggtt tggatagcaa
     7141 ggaagctcat tacctagcaa atctttacgg ttcaaatgca ccgaaggtct ttgcacttgc
     7201 tcacagcttg gaacaagcgc caggtcttag cttagcagac accttgtccc ttcactatgc
     7261 aatgcgcaat gagttgactc ttagcccagt tgacttcctt cttcgtcgta ccaatcacat
     7321 gctctttatg cgtgatagct tggatagtat cgttgagcca gttttggatg aaatgggacg
     7381 attctatgac tggacagaag aagaaaaagc aacttaccgt gctgatgtaa aagcagctct
     7441 tgctcaaaac gacttagcag aattaaaaaa ttaagaaaaa ataaaagagg tggagggtag
     7501 caatccttgt cgcccgcccc ttttttaatg gagacagaaa aatgatgagt gaattatttg
     7561 gagaattttt agggacttta atcctgattc ttctaggaaa tggtgttgtt gcaggtgtgg
     7621 ttcttccaaa aaccaagagc aacagtgcag gttggattgt gattactatg ggttggggga
     7681 ttgcagttgc ggttgcagtc tttgtatctg gcaagctcag tccagctcat ttaaacccag
     7741 ctgtgaccat cggtgtggcc ttaaaaggtg gtttgccttg ggcttccgtt ttgccttata
     7801 tcttagccca gttcgcaggg gccatgctgg gtcagatttt ggtttggttg caattcaaac
     7861 ctcactatga ggcagaagaa aatgcaggca atatcctggc aaccttcagt actggaccag
     7921 ccatcaagga tactgtatca aacttgatta gcgaaatcct tggaaccttt gttttggtgt
     7981 tgacaatctt tgctttgggt ctttacgatt ttcaggcagg tatcggaacc tttgcagtgg
     8041 gaactttgat tgtcggtatc ggtctatcac taggtgggac aacaggttat gccttgaacc
     8101 cagctcgtga ccttggacct cgtatcatgc acagcatctt gccaattcca aacaagggag
     8161 acggagactg gtcttacgct tggattcctg ttgtaggccc tgttatcgga gcagccttgg
     8221 cagtgcttgt attctcactt ttctagttta tactcttcga aaatcaaatt caaaccacgt
     8281 cagcgtcgcc ttaccgtact caagtacagc ttgcggctag cttcctagtt tgctctttga
     8341 ttttcattga gtattagaaa acaattatgt tgatagagct tgggcaagag cccaatttca
     8401 gcaaaaaatg aagtaaatct tctcataata aaacgcatca tatcaagcac gaaaattcca
     8461 cgaggtcaac tacagtcaga aagctgaaca acaagccaaa acgcccaaaa aaggcggcaa
     8521 aaagcaagca cctgcaagca acgtgccgaa atggtcaaat cctgattatg tcaacgaatt
     8581 agacccaaaa atcgttgata tgctagtaga atttcacaag tcacaaggca ctttggaaac
     8641 tcccgaggcg caagcagaaa tcgcccaaaa acgtgaagaa atcgagcaaa ggagagctga
     8701 gcttgagggt aaaaaacaag agcttttgaa ccgcttgaac aaatagagtt tcgcaagtat
     8761 tatgcttaca aattacttga gcaattaact aaaatataaa ccctgccttt atatctatgc
     8821 agggtttata ttttagaaat tcacgtaggt tgttacggtt tttacatacc cagtatagtt
     8881 tgagtttcta tagtattcag tgataaactt ccattttctt tgagcaacat ggatataagt
     8941 acttgttatg tagtatggat atgggctttg tgaatccaag taagactgat aagcttgtat
     9001 accaaaatat gctccaccaa ttattgcacc ccatggaccc cccaataaag cacctatcct
     9061 accaatcata taactgattc cagcaccagt catgaagtta gcgaatgtgt tagcttgttt
     9121 attcccatgt attgtgttga cgtaattcca aacattagga tcgtatgatc taaaagatat
     9181 atttaggtcg atttcattct tttgataagc catataaaat gccccattga tatagacgcc
     9241 gtcagcacgt cgttcaatag tgtctacact tccatctgga ttgacaacct caagaacttc
     9301 atcgcttaaa atatttactt gcgtatctcc gaaccgcact gatgagccat tctcaaactg
     9361 agcctcacca gatacaactt tagagtttgc cgataagcta tcatcagcaa aaacaaacaa
     9421 gcgacgggga aatgctagac atacagaaaa cagacataac tagcaaacac atgcatttaa
     9481 acatcttaga cataacggaa actcctttgt atttttgatt tttttcaact tttattatac
     9541 aataaaacca aataaaaaga aagcggtaac aatatgctta atgcgaaaat tttttatata
     9601 tttttatgtt tgatcgttat cgaaactaca ggcttgttgt tgttgaaaag aggtctcgaa
     9661 atgggttatt tagacacaga agctattatc ctcgcagttt tttcatttgc tttttacaac
     9721 ctatgttcat tcgcttgggt ctgctctaca ataaaaaata aatagacgta ttttcaaaaa
     9781 aaaaaaaaat gcatatttat cttagcaaaa cgacgattta aatcgtcgtt tttttgtagt
     9841 acgacgggca tgtcgtatat ctgaggtgta agtcctcggt gggcacctgc taccggtgaa
     9901 cccaatagcg attcccaagc ctgactatcg tgaggtagca gggagaggaa gggatagcga
     9961 aatcgtggct ctacgaacag gaacgtgata gtaaggcgta tatagcggat aaggaggctt
    10021 caaactctaa agtccaaaaa ggtagtcgta acctatatgt gtaaatcacg agagtaattg
    10081 aattcggact aaggtttgtg tgaaaaagat aaatctttct agagtctaaa gactctgcgt
    10141 cagatttcct attttcactg taacctttta acgtcctcat atcttgtata aacgaggaaa
    10201 gatgtacgac ttattccgtg aggtttcatg agcgctgaaa gcgtagtaac aacgaatcat
    10261 gagaagtcag ccgagcccat agtagtgagg aaacttctgt agtggaagtg gagcgaaggg
    10321 gtgaatactc aaacagtctg gggagagact gtttgaggtc tgtcgctaga aagagaaaac
    10381 gacagatcga agtaatccta cttcacttgt gtctgtaaaa tgagtggtct gatagaactg
    10441 gactttgaca cgtaatgact agatgaaggt tcaccaatat aagatgtccc tcaggcacca
    10501 aaacaagaaa ggaatacgca catgtcaaaa ctgctagata agatattatc acgcgaaaat
    10561 atgctggaag cctacaatca agtaaaatcc aataaaggct cagctgggat tgatggaatg
    10621 actatcgaag agatggataa ttatctcaga caaaactggc gcttgactaa ggaactgata
    10681 aaacagagaa aatataagcc tcaaccagtt cttaaagttg agatacctaa accagacgga
    10741 ggcatccgtc aactaggaat tccaacagtt atggatagaa tgattcaaca ggccattgtc
    10801 caagtcatga gccccatttg tgaaccccat ttctcagata cgagttatgg tttcagacca
    10861 aataggtcat gtgaaaaagc catcatgaag ctcttagaat acttaaatga cggctatgag
    10921 tggatagtgg atatagacct agagaaattt ttcgatacag ttcctcaaga tagattgatg
    10981 tccttagtac ataacattat cgaagacgga gatacggaat ccttgattcg taagtatctt
    11041 cattcaggtg ttatcattaa tggtcaacgt tataaaacac tagttggtac accacaggga
    11101 ggaaatttat ctcctctctt atccaatatc atgcttaatg aattggacaa ggaattagaa
    11161 aagaggggac ttcgatttgt gcgctacgca gatgattgtg tgattacggt cggaagcgag
    11221 gcagcctcta agcgtgtgat gtattcagtc agtcgtttta ttgagaaacg gctaggtttg
    11281 aaagtaaaca tgaccaagac taagattacc agaccaagag agttgaaata tctaggtttt
    11341 gggttctgga aatcatcaga tggttggaaa agccgtccac atcaagatag tgttcggaga
    11401 tttaagttta aattgaagaa actaacacag aggaaatgga gtatagacct aacaagacgt
    11461 attgagcaac tgaatttgtc tattcgagga tggataaact atttctcatt gggaaatatg
    11521 aaaagtatag tcgccagcat agatgagcgc ttgcctactc gcctacgagt gattatctgg
    11581 aagcaatgga agaagaaatc gagacgatta tggggattgc ttaagttagg agttcctaaa
    11641 tggatagcag ataaggtatc tggctggggc gaccattatc aattagtagc tcagaagtcg
    11701 gtacttaaac gtgctatatc aaaaccagtc ctggaaaaac gtggactggt ttcgtgtttg
    11761 gattattacc ttgaacgaca tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggca
    11821 cgtacggtgg tgtgagaggg gctagagatt atcccctact cgattaactc ccctgaaatt
    11881 tattttaatt atgcaaattt cacgtatttt tgatgctgag acgacgatcc tgggaacttt
    11941 tcagatattt ttttgactat ctaaatctat cattagaaaa gcttagagcg ccaaaggatt
    12001 tgagcgtttt tctgattttt aagacttttt cccagtctct ttttcgattg aagatgtaat
    12061 tattctacta actaactaac ttcttagtac tagccaacaa cgataatcat aattcctcct
    12121 aaaattagga ataataaagg caatagtttt tgttttttca tgtaaaaaac ctcacttttg
    12181 ttttctgcta ttttatgcta aaatattaaa aatcaaattt aattccaaag tttgtaacta
    12241 aagggggagc gctacatgtc taattcattt gtcaaattgt tagtctctca attatttgca
    12301 aatttagcag atattttctt tagagtaaca atcattgcta acatatacat tatttcaaaa
    12361 tcagtaattg ccacatcact agttcctatc ttaataggaa tatcctcttt tgttgcgagt
    12421 cttttagttc cgttggttac taaaaggtca gcgctaaata gggttttatc tttatctcaa
    12481 tttggaaaga ctatattatt ggcgatactg gtaggaatgt ttaccgtaat gcaatccgta
    12541 gcgcctttgg tgacctatct atttgttgtt gcaatttcca tactagatgg ttttgcagca
    12601 cccgtttcct atgctattgt gccacgctat gcgaccgatt tgggtaaggc taattcagcc
    12661 ttatcaatga ctggtgaagc tgttcaattg ataggttggg gattaggtgg actcttgttt
    12721 gcaacaattg gtctgttacc taccacgttt atcattttag tcttgtatat catttctagc
    12781 tttctgatgt tatttcttcc taacgctgaa gtggaggtgt tagagtcaga aactaatctt
    12841 gaaattttgc tcaaaggttg gaagttagtt gctagaaatc ctagattaag actttttgta
    12901 tcagcaaatt tattggaaat tttttcaaat acgatttggg tttcttccat tatacttgtt
    12961 tttgtaacgg agttattaaa taaaacggaa agttactggg gatattctaa tacagcatac
    13021 tctattggta ttataattag tggcttaatt gcttttaggc tatctgaaaa gttccttgct
    13081 gctaaatggg aaagtattct ttttcctctt gtagctatgg caatagtgac actgactatt
    13141 ctatattttc caaacgcaca gatgttttta ttattttcag ctttagttgg tatgttatcg
    13201 caactaaaag aagttcctga aagtgtattt cttcaggaaa cagtagagga aaatcattta
    13261 gttaatgtct attccgttct tgaagtgatt tctacattag cattttcagt atttgttttg
    13321 ctaatgagct atattactga gagttttggt attagcatca gtttttggct atcagccatt
    13381 tgtctgatga tagaagctat tttaatttat atcagacgag attattttaa atgagagagt
    13441 ggttaaaaag tctttaaaaa tcagaaaagc gcatagtatc aggtgttgaa aaaacttgat
    13501 attgtgtgtt ttattatggg aagatttact tcattgtctc ctgaaatgga gttttgaagc
    13561 aggatcactc tatttgaaaa tatacataga aaaactgtat aatccttaaa ataagctgaa
    13621 atctattgga aacatacggt aaacaattga aaagatacta tataaagtgg tacaatggta
    13681 gaaaaataag ctagtaagaa tcactcttat tttagcgaaa aattacagaa atgaatggtt
    13741 tttcttgatg aaacagagaa aagaattgta cctctttctt ggtcggacag ccttgtattt
    13801 tcttatcttt ctagggctgc tttacttctt tagctatctt ggtcagggtc aaggaagctt
    13861 tatctataat gaattttaac ttgaaggaga atccctattg tgtcaaataa accaatagca
    13921 gatatgattg aaaccattga gcattttgct cagacacagc ctagctatcc tgtctataat
    13981 gttttggggc aggaacacac ttatggcgat ttaaaggctg attcggatag tttggctgca
    14041 gtcattgacc aactaggctt gcctgagaag tctcctgtgg ttgtttttgg tggccaagaa
    14101 tatgaaatgt tggcaacctt tgtagcgctg actaagtcag gtcatgccta cattccaatt
    14161 gatagccatt cggccttgga gcgagtttca gctattttag aagtagcaga gccaagcttg
    14221 attattgcca tttcagcctt tcccttggag caggtttcta caccaatgat aaatctagct
    14281 caggttcaag aagcctttgc ccaagggaat aactatgaaa tcacgcatcc agtcaaggga
    14341 gatgataatt actacattat ctttacttct ggtacgactg gtaagcctaa gggagtgcag
    14401 atttcacatg ataatctcct cagctttaca aactggatga ttacggataa ggaatttgcg
    14461 acaccgagtc gtccgcaaat gctggcacag ccaccttatt cttttgactt gtctgtcatg
    14521 tattgggcac cgaccttggc acttggtggt acgcttttca ctcttccttc agtcatcact
    14581 caggacttca agcaactctt tgcggctatc ttttcattgc caatcgctat ctggatatca
    14641 acaccatcct ttgcagatat ggccatgttg tctgaatact tcaacagtga gaaaatgcct
    14701 ggaatcacgc atttctactt tgatggtgaa gaattgacgg tcaaaacagc tcaaaaactg
    14761 cgcgagcgtt tcccaaatgc ccgtatcatc aatgcttacg gcccaacaga agcgacagta
    14821 gctctgtcag cagttgccgt gacagacgag atgttagcga ctctcaaacg cctaccaatc
    14881 ggctatacca aggctgattc tccaaccttt atcattgacg aggaaggaaa taaactgcca
    14941 aatggcgaac agggagaaat cattgtttct gggccagctg tttcaaaagg ttatatgaac
    15001 aatcctgaaa aaacagcaga agccttcttt gagtttgaag gtctgccagc ctatcacaca
    15061 ggcgatgtgg gaaccatgac agatgagggc ttgcttctct acggcggacg catggacttc
    15121 cagattaagt tcaacggtta ccgcattgag ttagaagatg tctctcaaaa cctcaacaag
    15181 tctcgcttta tcgaatctgc tgtcgcagta ccgcgctata acaaggacca caaggtacaa
    15241 aatctattgg cttatgtcat cttaaaagac agtgttcgtg agcagtttga gcgagatatc
    15301 gatattacca aggccatcaa ggaagacctg acagacatca tgatgtccta catgatgcca
    15361 tctaaattcc tttaccgaga cagtttgcca ctgactccaa atggaaagat tgacatcaaa
    15421 ggattgatta acgaggtgaa taagagatga tggagttttt tcaacagctt cctcatttag
    15481 agccatatgg caatcctcag tattttgttt atgtgattgc tgcaaccttg cccatcttta
    15541 taggcctctt tttcaagaaa cgctttgcct ggtatgaagt gttggtaagt ctcttcttta
    15601 ttgtcaccat gttggtgggt ggaaagacca atcaactagc tgccttgggt atttaccttt
    15661 gctgggaaat attgctcctg cttttctaca agcattatcg aaaaagcaag gatggcaagt
    15721 gggtcttcta cttagttagt tttctgtccc tacttccgat tatctttgtc aaggtgcaac
    15781 cagctatcaa tggaacgcag tctttgcttg ggttcttggg aatttcttac ctgacctttc
    15841 gttcggttgg gattatcatc gagctgagag atggagtgat taaggatttt accctctggg
    15901 aattcctccg tttccttctc ttcatgccaa ctttctcgag tggtccaatc gatcgcttta
    15961 agcgatttaa tgaaaattat caggctattc ctgagcgaga tgagttgatg gatatgctgg
    16021 atgaatctgt ccgctatatc atgtggggct ttttgtataa gtttatccta gctcatgttt
    16081 taggagagac cttactacct cctctgaaga atttagcctt gcagtcaggt ggcttcttta
    16141 atctctatgc cttggcagtt atgtatactt ttggtctgga gctcttcttt gactttgcag
    16201 gttattctat gtttgctttg gccatctcaa acttgatggg aatccgtagc cctatcaact
    16261 ttaacaagcc ctttttatca agggatttaa aggagttttg gaatcgctgg catatgagtc
    16321 tgtccttctg gttccgtgac tttgtcttta tgcgaatggt gatggtgtta accagaaaga
    16381 aagtctttaa aaatcgtaat gtaacctcaa gcatggccta cattgtaaat atgctgatta
    16441 tgggattttg gcatggtgtg acctggtact atatcgccta tggactcttt catggactag
    16501 gcttggtcat caatgatgcc tgggttcgca agaaaaaaac gctcaataag gaacggaaaa
    16561 aagcagggaa ggctgcccta cctgagaatc gctggattca gttgcttggc atggttgtca
    16621 ctttccatgt tgtcatgttg tcattcttaa tcttttctgg attcttgaat aatctatggt
    16681 ttaaaaaata aaaggaaata aaatatggat atcaaatcag aagttattga aattattgat
    16741 gagttgttta tggaagatgt ttctgacatg atggatgaag atctttttga tgcaggtgtc
    16801 ttggatagta tgggaacggt tgagttgatt gtggagattg agaaccgttt tgacattcgt
    16861 gtccctgtaa cagagtttgg tcgtgacgac tggaatacag ctaataaaat catagctggt
    16921 attgtggagc tacaaaatgc ttaaacgctt atggatgatc ttcggaccgg tcttgatcgc
    16981 tggtttgttg gtttttctgc tcattttctt ttatcctact gagatgcatc ataatctagg
    17041 agctgaaaag cgttcagcag tggctactac tatcgatagt tttaaggagc gaagtcaaaa
    17101 agtcagagca ctatctgatc caaatgtgcg ttttgttccc ttctttggct ctagtgaatg
    17161 gcttcgtttt gacggtgctc atcctgcggt attagctgag aaatacaatc gttcctaccg
    17221 tccttatctt ttaggacagg ggggagctgc atcgcttaac caatattttg gaatgcaaca
    17281 gatgttacca cagctggaga ataaacaagt tgtgtatgtt atctcacctc agtggttcag
    17341 taaaaatggc tatgatccag cagccttcca gcagtatttt aatggagacc agttgactag
    17401 ttttctgaaa catcaatctg gggatcaggc tagtcaatat gcagcgactc gcttactgca
    17461 acagttccca aacgtagcta tgaaggacct ggttcagaag ttggcaagta aaggagaatt
    17521 gtcgacagca gacaatgaaa tgattgaatt attggctcgt tttaatgaac gccaagcctc
    17581 cttttttggt cagttttcgg ttagaggcta tgttaactac gataagcatg tagctaagta
    17641 tttaaaaatc ttgccagacc agttttctta tcaagcaata gaagatgttg tcaaagcaga
    17701 tgctgaaaaa aatacttcca ataacgagat gggaatggaa aattatttct ataatgagca
    17761 gatcaagaag gatttgaaga aattaaagga ttctcagaaa agctttacct atctcaagtc
    17821 gccagagtat aatgacttgc agttggtttt aacacagttt tctaaatcta aggtaaaccc
    17881 gatttttatc attccacctg ttaataaaaa atggatggac tatgctggtc tacgagagga
    17941 tatgtaccaa caaacggtgc agaagattcg ctaccagtta gaaagtcaag gttttaccaa
    18001 tatagcagat ttttctaagg acggcgggga gcctttcttt atgaaggaca ccattcacct
    18061 tggttggttg ggttggttgg cttttgacaa ggcagttgat cctttcctat ccaatcccac
    18121 accagctccg acttaccatc tgaatgagcg ctttttcagc aaagattggg cgacttatga
    18181 tggagatgtc aaagaatttc aatagataat ataatataga agagttcaag aatgaaacta
    18241 gttttcacgt tttttcttga ctcttttttt gcttgtgata taattaactg gtaaacaaaa
    18301 tgtcaaagaa tagtattttt ctcttaaaaa agagaagtct aaaaggaaag gagtcagata
    18361 tgagacagct agcaaaggat atcaatgctt ttttgaatga ggtgattttg caggcggaaa
    18421 atcagcatga aatcctaata ggtcattgca ctagcgaggt ggccctgacc aatactcagg
    18481 agcatatcct tatgctcttg tcagaggaat ctttaacaaa ttcagaattg gcccgtcgtc
    18541 tcaatgtcag tcaggcggca gttaccaagg ccattaagtc tttggtcaag gaagggatgt
    18601 tggaaacatc taaagattct aaagatgcgc gtgtgatttt ttatcagttg actgacttgg
    18661 ctcgtccaat cgctgaggag caccaccatc accatgagca tacactttta acctatgaac
    18721 aagtggcgac tcagtttact ccaaatgaac aaaaagtgat tcagcggttt ttgactgctt
    18781 tagtaggaga aatcaaataa tgagatatat tacggtagag gatttgtcct tctattatga
    18841 taaggagcct gttcttgaac atatcaatta tagtgttgat agtggggaat ttgttacctt
    18901 gactggggaa aatggagcgg ctaagacgac gctcatcaag gctagtcttg gaattctgca
    18961 accacgcatt ggaaaggtgg ctatttcaaa gacaaatacg caaggtaaga aattgagaat
    19021 agcctatctt cctcaacaaa ttgccagttt taatgctggt tttccaagta cagtctatga
    19081 atttgtcaag tcgggtcgct atccgagaaa aggctggttc cgtcgtttga atgctcatga
    19141 tgaggagcat atcaaggcca gtctggactc agttggcatg tgggaacatc gagacaaacg
    19201 cttggggtct ctatctgggg gacaaaagca gcgagcggtg attgcgcgta tgtttgcttc
    19261 tgaccctgat gtgtttatcc tagacgagcc gacaacgggg atggatgcag gaagtaaaaa
    19321 tgaattttac gaactcatgc accacagcgc ccatcatcat ggcaaggctg ttttgatgat
    19381 tacccatgac cctgaagaag ttaaggatta tgcggatcgc aatattcatc tagtccgtaa
    19441 ccaagactcg ccatggcgtt gtttcaatgt tcatgagaat ggccaggagg tgggccatgc
    19501 ttagtttatt atcttacgac tttatacaac gcgccttttt ggcggttatt gctatgagtc
    19561 ttttctcacc ggtattggga accttcctca tcttgcgtcg tcagagtttg atgagtgata
    19621 cccttagcca cgtctcactt tcaggtgtag cctttggtct ggttttgggg atttctccaa
    19681 ctgtttctac tattgccatt gtcttgattg cggcggtctt tctggagtat ctccgtacgg
    19741 tttacaagag ctttatggaa atcgggacag ctatcctcat gtcaacaggt ctggctgttt
    19801 ctctgattgt catgagcaag ggtaaaagct cgagttcaat gagtttggac caatatctct
    19861 ttggttcgat cgtgactatc agtgaagaac aggtcatttc cctctttgtc attgcggcgg
    19921 ttgttttgat tttgaccttt ctctttcttc gtcctatgta tatcttaact tttgacgaag
    19981 atacggcctt tgtggatggc ttgccagttc gtaccatgtc cattcttttt aacatggtga
    20041 caggggtggc tattgccctt atgattcctg cagcaggagc tcttctggta tcgaccatta
    20101 tggtcttgcc agctagtatt gccctgcgtc tggggaaaaa ctttaaatcg gttatgctgc
    20161 ttgccagtgc gattggcttt ttgggaatgg tagcaggact ttacatttcc tactatgcag
    20221 aaacacctgc aagtgcaagt attaccatta tttttgtaac tgtctttata ctaatcagtt
    20281 tagtaagacg ttttatcaaa taggagacga acgtgaaaaa aattagctta ttactagcca
    20341 gtctatgtgc cttgttttta gtggcttgtt ccaatcaaaa acaggcagat ggtaaactca
    20401 atatcgtgac aaccttttac cctgtctatg aatttaccaa gcaagtcgca ggagatacgg
    20461 ctaatgtaga actcctaatc ggtgctggga cagaacctca tgaatacgaa ccatctgcca
    20521 aggcagttgc caaaatccaa gatgcagata ccttcgttta tgaaaatgaa aacatggaaa
    20581 catgggtacc taaattgcta gataccttgg ataagaaaaa agtgaaaacc atcaaggcga
    20641 caggcgatat gttgctcttg ccaggtggcg aggaagaaga gagagaccat gaccatggag
    20701 aagaaggtca tcaccatgag tttgaccccc atgtttggtt atcaccagtt cgtgccatta
    20761 aactagtaga gcacatccgc gacagcttgt cagcagatta tcctgataaa aaagagacct
    20821 ttgagaagaa tgcagctgcc tatatcgaaa aattgcaagc cttggataag gcttacgcag
    20881 aaggtttgtc tcaagcaaaa caaaagagct ttgtgactca acacgcagcc tttaactatc
    20941 ttgccttgga ctatggactc aaacaagtcg caatctcagg cctttctcca gatgcagagc
    21001 catcagctgc tcgcttggca gaattgacag agtatgtcaa gaaaaataaa atcgcctata
    21061 tctattttga agaaaatgcc tcacaagccc ttgctaacac actttcaaaa gaagcaggtg
    21121 tcaaaactga tgtcctcaat cctttagaaa gtctgacaga agaggacacc aaggctggag
    21181 aaaactacat ttccgtgatg gagaaaaacc tcaaggcttt gaaacaaaca acagaccaag
    21241 aaggcccagc aatcgaacct gaaaaggcag aggataccaa gacagtccaa aatggttact
    21301 tcgaggatgc agctgtcaag gaccgcacct tgagtgacta tgcaggtaac tggcaatcag
    21361 tttatccttt ccttgaagac ggcacgtttg accaagtctt tgactacaag gctaagttga
    21421 ctggtaagat gacccaggct gagtacaagg cttactatac aaaaggctat cagacagatg
    21481 tgactaagat taacattact gataatacta tggaatttgt tcaaggtgga caaagcaaga
    21541 aatacactta caagtatgtc ggtaagaaaa ttttgactta caagaaaggc aatcgtggcg
    21601 tgcgtttcct ctttgaagcc acagatgctg acgctggaca gttcaagtat gttcagttta
    21661 gtgaccacaa tattgcccca gttaaggcag aacatttcca tatcttcttt ggaggcacaa
    21721 gccaagaagc tctatttgaa gaaatggata attggccaac ctactatcca gataacctat
    21781 ctggccaaga aatcgctcaa gaaatgttgg cgcattgatg agaaatcgac tagttcataa
    21841 gagctagtcg gttttttgat actagatggc taacttcatt atagaccttt cagaacttta
    21901 aacaataaat aaaactcttg aaatatctgg gcttatatgc tagaatgtag ttagtgtata
    21961 aggttcatta gaacaccaaa gcccctaact agtgccatag ttaagggctt ttttgacgta
    22021 tcttagcgat ttaacgggtg tttataggct agtcagtcgg tctacttctt accatctagc
    22081 catttgcaga cgaaatacaa gataattcca gctataacat ctgctataat agtaagagca
    22141 agctctggta taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg
    22201 gtaaccgatg acaaaagtat tatatcacac taaatttaga tcatcaacct cacttaatgc
    22261 ttgaactatt gtagattata tgctaaaatg tagttaattg ataaggttca ttagaacacc
    22321 aaagccccta actatggccg tagttaaggg cttttttgac gtatcttagc gatttaacgg
    22381 gtgtttatag gctagtcact cggtctactt cttactatct agccatctgc agacgaaata
    22441 caagataatt ccagctataa catccgctat aatagtaaga gcgagctcta tgataaggct
    22501 cattagtttc acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaaa
    22561 tagtatacca caatacattt agatcatcaa ggtcacttaa ttcttgaaat atagggtcta
    22621 ggcgacaaag tctttaaaat cagaaaaacg cataatatca ggtgtgcaaa aacttgatac
    22681 tatgcgtttt attgtgggaa ggtttactcc attttctcct gaaattgagt ttttgtccag
    22741 cctctgtttt tagggttgct gagaaaataa tgtcatgtgg tgaatatttg taaatcagtc
    22801 agcagacaga acgaatactc ttcgaaaatc tcttcacatc atgtcagctt cgtctttccg
    22861 tatatatgtg actgacttca tcagttctat ctacaacctc aaaacagtgt ttcgagctga
    22921 cttcatcagt tttcaaatct gtactttgag caagctgaga ctagcttcct atttgatttt
    22981 cattgaatat cagaaaccca ttctccatca aataattcga ctgcgtctaa taatttttga
    23041 tctggcacgg tgtctgaaat aaaggttgtg tatttggaga ggggattaat tttaaaaaat
    23101 ccagtcttgt aaaatttaga actatcaatc agtaagatgg tttcatgggc tttgtcaata
    23161 atattctttt ttgaaatagc ttggctgaga gaagcttcat aaacatattg gtcatcaata
    23221 cctcttgctg aacaaaatgc taaatcgata ttaaaatgat ctaataaaga attttcctta
    23281 tcatagttga ccacggaaca ggattgatgt ttgacctcgc cagatgtgat aaagattttg
    23341 gagctatctt taacagtttc agatagggtt tgtgcagtat gtaaaccatt tgtaaaaata
    23401 atcaaattat caagttcaga aagataggga caaagttcgt agacagtagt actggaatcc
    23461 agataaacac acataccaga ccgaataaag tctttagcga gactagcgat tagtcttttt
    23521 tgcctagtac tttctccttc ccgtatttga tgagaaagtt caattgtgtt catagaggac
    23581 agggtcacgt atccgtgctt tcttttgata agaccttgat tttctaagaa aattaaatca
    23641 cgacgtaagg tacttgtgct ggagaaagtg atttctgcca gctcttttac ggcaattctt
    23701 tttttctttt tgataatttc aatcaattca agtacacgtt catcttttat cataagctcc
    23761 tcctaattta tcatttcaac tatattatag cacaaattgg aggaatttga attattttta
    23821 tgaatattgg gttaacattt gaacattatt caagtaagcg ttcacatatt gaaaaaataa
    23881 aacgtgggga ttataataag gttaatcaag gacgaagaga gaagaaaaat ggaagcggtt
    23941 ttagcaatag atttaggtgc gacttctgga agagcaatcg ttggttacct ttctgaaaat
    24001 aaactagtaa tggaagaaat aaatcgcttt tctaatctac ctattagagt aaaagggcat
    24061 ttatcttggg atattgactt tctactagct aaaattcttg aaagtatccg cttggctaat
    24121 actagttaca agattttatc tatcggtatt gacacatggg gagttgattt tggactgatt
    24181 gataatgaag gtaagctgtt attacaacct gttcattatc gtgatgaaag aacaaaggga
    24241 gtgttaaagg aaatatctga aatgactgaa ttagaaaaac tgtattcaga gacaggaaat
    24301 cagattatgg agataaatac cttgtttcaa ctctttaagg cacgtcaaga atctcctgac
    24361 tctttctata agaccaataa gattctttta atgccagatt tgtttaatta tctcttgaca
    24421 ggtaagtttg ctacagaaaa aagcattgct tcaacaactc aattatttga tcctaggagt
    24481 caaaattgga atcagaatat cttaaaacta tttgaattgg attcaacttt acttcctgaa
    24541 attgtttcag agggaaatgt ccttggaagg ataaaagagg agtatggttt aggcgatatt
    24601 cctgttgtga atgtttgtag tcatgataca gcaagcgcga ttgtctcagt acctaagaca
    24661 gaagatagtt tgtttatttc atcagggact tggtctttgg ttggagtgga gctttcttca
    24721 cctattctta gtaccgaatc cttcagttat ggatttacaa atgaagtcgg taaagatgga
    24781 gtgattacat ttctgaagaa ttgtacaggg ttgtggatca tagaggaact aagacgttca
    24841 tttgaacgaa gagggaaagc ctattctttt gatgatatta ggacaatggt ggagaaagaa
    24901 aaagaaaatc ttcctctgat tgatactgaa tcaactgaat ttgcaacaga atctgatatg
    24961 cacaagactt tgacagaata tctagcttat catcatgaaa ctggagagtg gacagatgga
    25021 caactattta agatcgttta tgaaagccta gctgaaacgt ataaggaaac aatagagtta
    25081 ctagaagaac taactcataa ggtttataag aggatatatg tgattggagg aggtgctaga
    25141 gccagttact ttaaccaaat gattgctgat agaactggta aagaagttct tacaggttca
    25201 actgaggcta cagctgtggg gaatattgtt gtgcagctca tagctatggg acaattaaaa
    25261 gggatggaag aagctcacca tgttattgag gagttcctac aattagagag ttattactcc
    25321 caaaagaatt aaaaagattg agagtttgta aatttgcctc cctccccctt cttaagtttt
    25381 gtacaagaag gggggataat tggtgaattg aaaaatattt agtgttttga tatgaggagg
    25441 acaagaatgt cagatgtaaa acaagaatta attaagtatg gcaagaagct agtagaaaca
    25501 gatttgacga aaggaacagg tgggaatctc agtgttttcg atcgtgaaaa acaattgatg
    25561 gcaattaccc cgtcgggtat tgatttcttt gaaatcaaag aatccgatat tgtagtgatg
    25621 gatattaatg gaaatgttgt agagggagaa cgcttgccat ctagcgaatg gtatatgcat
    25681 ttgattcaat atcaaactcg tgatgatatc gatgcaatta tccatgctca tacaacttat
    25741 gcaacagtat tagcttgtct cagagaacca cttccggcta gtcattatat gattgcagtg
    25801 gcagggaaag atgttcgggt agctgagtat gcaacatatg gtacgaaaga attggctgtg
    25861 aatgcagcta aagcaatgga aggtcgtaga gcagttttac tagcgaatca tggaatttta
    25921 gcaggtgcac aaaatttatt gaatgcattt aatattgttg aagaagttga atattgtgca
    25981 aaaatttatt gtttagctaa gaattttgga gagccagtag ttcttcctga tgaggagatg
    26041 gatttaatgg cagaaaaatt taaaacatac ggtcagagaa aatagggagg atattaatgt
    26101 taaaacatat accgaaaaat atttctccag atttattgaa gactttaatg gaaatgggac
    26161 atggagatga aatagtatta gctgacgcga attatccttc tgcctcatgt gcaaataagc
    26221 taattcgttg tgatggtgta aatattccag aattattaga ttccattctg tatttaatgc
    26281 cattagatag ttacgtcgat agttcaattc agtttatgaa cgttgtttcg ggtgatgata
    26341 ttcctaagat atggggtacc tatagacaga tgattgaagg tcatggtaca gatcttaaaa
    26401 cgattactta tcttagaaga gaagactttt atgaacgtag taagaaagct tatgctattg
    26461 ttgctacagg agaaacttca ctttatgcta atattatcct taagaaagga gtagttgttg
    26521 aaagagaaaa tgtttaatag aggaatttta gttgccagtc atggtaattt tgctagcgga
    26581 gctctcatga ccgcagaaat gtttgttggt gagacaacaa atgatagagt taggacatta
    26641 ggtttgatgc ctggagagaa tattgtagag tttgaacatt attttaaaaa tcaagtaaat
    26701 gaactgttag actcaaatca agaggttatc gttttgactg acttgattgg aggaagtcct
    26761 aataatgtgg ctttgtcacg gtttttaaat ttggattcag ttgatattgt aacagggttt
    26821 aatatccctc tcctagtgga attaatatca agttatgatt caaaaatcaa tttagaagaa
    26881 attgttcaaa atgctcaaaa tagtttgttt aatgttaaac aacaacttaa cgtagaggag
    26941 gaagaggatt tatgtctata gagtttgttc gtattgatga ccgtctggta catggtcaag
    27001 ttgtcactac gtggctaaaa aagtatgata ttgagcaagt tatcattgtt aatgatcgca
    27061 tctcagaaga taaaacacga caatctattt taaagatttc tgcaccggta ggtttaaaaa
    27121 ttgttttctt tagtgtaaaa cggtttgtgg aagttttaaa ctctgtgcca ataaaaaaga
    27181 gaacaatgct gatatataca aatccaaaag atgtgtatga ttctattgaa ggaaatttaa
    27241 aattggagta cctcaatgta ggacagatga gtaaaacgga ggaaaatgaa aaggtaacgg
    27301 gaggtgtagc tctaggtgaa gaagacaaat attattttaa gaaaatagtt gataagggaa
    27361 cgagagttga aattcaaatg gttcctaatg ataaagttac aatgttggaa aaatttttat
    27421 aaaaataatt taaggaggta cagtatatgc tattcacaca agcattactg gtgacattag
    27481 ttgggattat tgccactatt gactataatg gaccgttatt tatgattcac cgtccgttag
    27541 ttacaagtgc aatggttggc ttagtcttag gagatttcac ccaaggtgtt cttattggtt
    27601 cagctcttga attaacttgg ctcggtgtaa caggtattgg aggttacact ccaccagata
    27661 ctatttcagg tgcgattatt ggtactgcat ttggtatttt gtctggtcaa ggagaaactg
    27721 ctggtatcgc tatagcagtt ccaattgcag ttgctaccca acagttggat gttcttgcaa
    27781 aaactttaga tgtttatttt gtgaaaaaag ctgataatga tgctaaaaac ggagattatt
    27841 caaagatcgg tttttatcat tattcaagtt tggttttaat cactttattt aaaattgtac
    27901 caattttcct agctattatg cttggagggg aatatgtggc agacttgttt gctaaggttc
    27961 caccaatcgt tatgcaggga cttaactctg caggtgcttt actaccttca attggttttg
    28021 gtatgctttt aaatatgatg ctcaagaaaa atatgtgggt attcttgttg attggattca
    28081 tttgttctgt gtatggagga atgtcaacca ttgggatctc actagttggt attgcggtag
    28141 catacttcta cgatatgatt ggaagtaaac cacaagaaac aacttcaagt agtgatgttg
    28201 aggaggatct tgatctatga tgaataataa agtaactaaa gttgaactta aaaaagtttt
    28261 caaacgaagt tttatgtatg gttcttcatg gaactatgag agaatgcaga acctaggttt
    28321 tctatataca attcttccag tattgaaaaa actataccca gacaaagatt cagcttctcc
    28381 tgcaatgaaa cgtcaccttg agtttttcaa tactcatcaa acagcggcac catttattct
    28441 tggagttact tccgctatgg aagaacaaga aggaaatgaa ggtgcagctt caattactgg
    28501 tattaaagtt ggcttgatgg ggccgctggc tggtctagga gatagtttgt tctggctgac
    28561 actagttcct atctgtttta gtattggtgc gtcttattct aaagacggcg gtgctttagg
    28621 tatctttatc gccttaatat tgtttaatat tattaatatt cctgttaaat atttcggttt
    28681 gaaatatggg tatactaagg gttctagtct tatccaagaa aataatacaa aaggaacatt
    28741 gaatcgcgtt acgagtatgg cgacagcatt agggctagta ctagtgggtg gtttgattcc
    28801 atcaatggtt ggtattaatt ttggattaga atttaagcag ggggaacttg ttatttctgt
    28861 tcaagaaatg attacaaaat taattccagg atttatccct atggctttga ctttattaat
    28921 gtgtaaatta attagaaaag gaaagaatcc ggttgtacta atctttagtg ttatggctat
    28981 tggagttatc ctagttgttt taggaatttt gaagtagtag aaagtgtgga ggtggtattt
    29041 gggatatcac ctccattttg gaagagaggt aaagagtgaa attatggtat aagaaagctg
    29101 cctcaaattg gaatgaagcc ttgccgattg ggaacggtca tttaggtggt atgatttatg
    29161 gttcagctac aaaagaatgt attcaactaa acgatgagac tatttggtat agaggaaagt
    29221 cagatagaaa taatccagac tcactattgc atcttaaaaa aattcgggaa tatcttttag
    29281 atggagaaat tcagaaagcc gaagaattga taaagttaac aatgtttgct accccaagag
    29341 atcaaagcca ctatgaatta cttggggaac tttacattga gcatatagat attcagtctt
    29401 gtgctctttc attgtatgaa agagagctag atttagatac agctatttct aatgttgtgt
    29461 ttgagcctaa tagttgtaat ttacaaataa aaagagaata ttttacgagt tttaataaga
    29521 atattttatg ttgccgtata gtgtcatcag ttcaaaacac attaaattta aacattaatt
    29581 tgggtagaaa taaacggttt aatgatgaag tatctaaact ggattcaagt acaattttaa
    29641 tgtcggcctc tgctggaggt agaaaaggtg ttcagtttaa agtggtatgt cattctaagg
    29701 ttacggatgg tgaagtaagt gtattgggag agacaatagt tattcggaat gctacagagg
    29761 tatttcttta tctcaaatca atgacggatt attggggaaa tatagatatt tcttctcttc
    29821 agggagaatt tagtagtatt gattacttta cagaaaaaga tgaacatgta aaaaaatatc
    29881 aggagcaatt taatagagtt gattttaaac tagactatag taaagattgt cttagcattc
    29941 caacgaatct acttcttgaa aacactaaaa agtatagtaa ctacttgact aacttgttat
    30001 ttcattatgg aagatatctg ttaatatcgt ctagtcaacc gaatggttta cctgccaatc
    30061 ttcaaggaat atggtgtgat gaattaaatc taatttgggg ttctaaatat acgattaata
    30121 ttaatactca aatgaattat tggatggtag gtccatgtga tttaccagaa gtagaatatc
    30181 cattatttga tatgctcgaa agaatgagag aaccgggaag actaaccgct aagaaaatgt
    30241 atggagctag aggttttaca gcacatcata atacggatgg ttttggcgat acggctcccc
    30301 aatctcatgc catgggggct gcaatttggg tattaactat tccatggtta tgtactcata
    30361 tttgggaaca ctatttatat ttccaagatg agcgtattct tacggaacat tttgaaatga
    30421 taaaagaagc atttcttttc tttgaagatt atttatttga ggtggatggc tacttgatga
    30481 caggtccaag tgtctcaccg gaaaataaat atcgcttaaa aaatggtatt gaaggaaatg
    30541 cttgtctatc atctacaatt gataatcaaa ttttaagata tttttgtgat tcatgcattg
    30601 gaattgcaaa acaattagga gacaattcgg attttattag tcgtgtgaag gagttaaaaa
    30661 agaaattacc tagaacaaaa ataggtagta atgggcaaat acaagaatgg ctagaggatt
    30721 atgaagaagt agagcctggt catagacaca tttcacctct atttgggctt tatccttata
    30781 atgagattga tattcataaa actccggaat tagcagaagc agctaaaatc actatcaata
    30841 ggagattatc aaacgctaac tttttatctt cacaggatag ggagcaagcg attaataatt
    30901 ggttagtaag tggtttgcat gctagtacac aaacaggttg gagtgctgca tggctgattc
    30961 atttttttgc gagactatat caaggtgaac ctgcttataa ccagattaat ggtttgttaa
    31021 ataatgcgac tcttggcaat ttatttcttg accatccacc atttcaaatt gatggtaatt
    31081 taggtttggt gagtggaatt tgtgaattat tagtacagag ccatcataat tggttatcac
    31141 taattccagc tttaccttct gcttggtcag aaggagaagt gaaaggtttc agagtaagag
    31201 gaggatataa ggtatcgttt gcttggaaaa atggggatat aacattccta aaattggaag
    31261 gaggaaacaa agatcaaaaa gtaagagtaa gaatatatgg caaaaatact gatgtacaaa
    31321 atattgaatt ggtatttaat tcagaaaaaa ttattgagtt aaatttttag gtataagtca
    31381 tgaataaaga aaaaataaaa agaaaattaa tcacaatact gtttgtatgt attgggatgt
    31441 tatgttttgg attgttagca ggagttaagg ctgataatcg tgttcaaatg agaacgacga
    31501 ttaataatga atcgccattg ttgctttctc cgttgtatgg caatgataat ggtaacggat
    31561 tatggtgggg gaacacattg aagggagcat gggaagctat tcctgaagat gtaaagccat
    31621 atgcagcgat tgaacttcat cctgcaaaag tctgtaaacc aacaagttgt attccacgag
    31681 atacgaaaga attgagagaa tggtatgtca agatgttgga ggaagctcaa agtctaaaca
    31741 ttccagtttt cttggttatt atgtcggctg gagagcgtaa tacagttcct ccagagtggt
    31801 tagatgaaca attccaaaag tatagtgtgt taaaaggtgt tttaaatatt gagaattatt
    31861 ggatttacaa taaccagtta gctccgcata gtgctaaata tttggaagtt tgtgccaaat
    31921 atggagcgca ttttatctgg catgatcatg aaaaatggtt ctgggaaact attatgaatg
    31981 atccgacatt ctttgaagcg agtcaaaaat atcataaaaa tttggtgttg gcaactaaaa
    32041 atacgccaat aagagatgat gcgggtacag attctatcgt tagtggattt tggttgagtg
    32101 gcttatgtga taactggggc tcatcaacag atacatggaa atggtgggaa aaacattata
    32161 caaacacatt tgaaactgga agagctaggg atatgagatc ctatgcatcg gaaccagaat
    32221 caatgattgc tatggaaatg atgaatgtat atactggggg aggcacagtt tataattttg
    32281 aatgtgccgc gtatacattt atgacaaatg atgtaccaac tccagcattt actaaaggta
    32341 ttattccttt ctttagacat gctatacaaa atccagctcc aagtaaggaa gaagttgtaa
    32401 atagaacaaa agctgtattt tggaatggag aaggtaggat tagttcatta aacggatttt
    32461 atcaaggact ttattcgaat gatgaaacaa tgcctttata taataatggg agatatcata
    32521 ttcttcctgt aatacatgag aaaattgata aggaaaagat ttcatctata ttccctaatg
    32581 caaaaatttt gactaaaaat agtgaggaat tgtctagtaa agtcaactat ttaaactcgc
    32641 tttatccaaa actttatgaa ggagatgggt atgctcagcg tgtaggtaat tcctggtata
    32701 tttataatag taatgctaat atcaataaaa atcagcaagt aatgttgcct atgtatacta
    32761 ataatacaaa gtcgttatcg ttagatttga cgccacatac ttacgctgtt gttaaagaaa
    32821 atccaaataa tttacatatt ttattgaaca attacaggac agataagaca gctatgtggg
    32881 cattatcagg aaattttgat gcatcaaaaa gttggaagaa agaagaatta gagttagcga
    32941 actggataag caaaaattat tccatcaatc ctgtagataa tgactttagg acaacaacac
    33001 ttacattaaa agggcatact ggtcataaac ctcagataaa tataagtggc gataaaaatc
    33061 attatactta tacagaaaat tgggatgaga atacccatgt ttataccatt acggttaatc
    33121 ataatggaat ggtagagatg tctataaata ctgaagggac aggcccagtc cctttcccaa
    33181 caccagataa atttaatgat ggtaatttga atatagcata tgcaaaacca acaacacaaa
    33241 gttctgtaga ttacaatgga gaccctaata gagctgtgga tggtaacaga aatggtaatt
    33301 ttaactctgg ttcggtaaca cacactaggg cagataatcc ctcttggtgg gaagtcgatt
    33361 tgaaaaaaat ggataaagtt gggcttgtta aaatttataa tcgcacagat gctgagactc
    33421 aacgtctatc taattttgat gtgattctat atgacaataa tagaaacgaa gttgctaaga
    33481 aacatgttaa taatttgtcg ggtgaatctg ttagtctaga tttcaaagaa aaaggagcaa
    33541 ggtatattaa agttaaatta ctaacgagtg gagtgccttt gagtttagca gaagtagagg
    33601 tttttagaga atcagatggt aagcaatctg aagaggatat agataaaata acagaagata
    33661 aagtagtctc tacaaataag gtagctactc aaagttcaac caattatgag ggtgtagctg
    33721 ctttagcagt tgatggtaat aaagatggag attacggaca tcattcggtg actcatacta
    33781 aggcagattc taacgcttgg tggcaggtcg atctgggaga agagtttacg gtttctaaag
    33841 ttgatattta taatagaaca gatgccgaac ctcagcgttt atctaatttt gatgttattt
    33901 ttctatcttc atcaggagaa gaagttttta gaagacattt tgataaagta gttgatggtt
    33961 tgttatcttt aaaagtacct tctgtagggg ctaagctagt caaaatagaa ttaaaatcag
    34021 cagctattcc gttaagttta gcggaagttg aagtctatgg ttcaaagaga actccgaaga
    34081 aactttctaa tattgcatta accaaagaaa ctcgacagag ttcaacggat tacaatggtt
    34141 tttctcgtct agcagttgat ggaaataaaa acggagatta tggtcatcat tcagtgactc
    34201 ataccaaagg agattctcct tcatggtggg agatagattt agcacaaacc gaagaattag
    34261 aaaagttaat tatttataat agaacagatg ctgaaattca gagattatca aattttgata
    34321 ttattatata tgattcaaat aatcatgaag tttttaaaca acatattgac agtttagaaa
    34381 gcaataatct atccatagac ttaaaagggc tgaagggaaa aaaggttaga atttctttga
    34441 gaaacgcagg aattccttta agtttggcag aggtagaggt ttatacttat aagtaatttt
    34501 aaaaattatc atcggtagta tgaaagaaac agaaaaataa gaggaaaata gtatgattca
    34561 acatccacgt attgggattc gtccgactat tgatggtcgt cgtcaaggtg tacgcgaatc
    34621 acttgaagta caaacaatga acatggctaa aagtgtggca gatttgattt caagcacatt
    34681 gaaatatcca gatggggaac ctgtggaatg tgtgatttct ccatctacca ttggtcgtgt
    34741 tccagaggct gcagcttccc atgagttgtt taaaaaatca aatgtttgcg caacaattac
    34801 agttacacca tgctggtgtt atggtagtga aactatggat atgtctccag atattcctca
    34861 tgctatttgg ggatttaatg ggacagaacg cccaggagct gtctatcttg cagctgtact
    34921 agcttcacat gctcaaaaag ggattccagc ctttgggatt tatggtagag atgttcagga
    34981 agctaatgat acagatattc cagaagatgt caaagaaaaa cttttacgtt atgcgcgtgc
    35041 agctcttgca actggcttga tgagagacac tgcttaccta tcaatgggta gtgtttcgat
    35101 ggggattggc ggttctattg taaatccaga tttcttccaa gaatacttag gaatgcgaaa
    35161 tgaatcggta gatatgacgg agttcacgcg ccgtatggac cgtggtattt atgacccaga
    35221 agagttcgaa cgtgctatgg tttgggtaaa agaacatatc aaagaagggg ttgaccgaaa
    35281 tcgtgaggat ttgattcttt ctaaagaaga gaaagaaaaa caatgggaat ttgttattaa
    35341 gatgttcatg attggacgtg acttaatggt tggtaaccca agacttgctg aacttggttt
    35401 tgaggaagaa gcggttggtc accatgcttt agtagctggt ttccaaggtc aacgtcagtg
    35461 gacagaccat tttccaaatg gagattttat ggaaactttc ctcaatactc agtttgactg
    35521 gaatggtatt cgaaaaccat ttgtatttgc gacagagaat gattcactaa atggtgtgtc
    35581 tatgctcttt aattatctat taacaaatac tccacaaatc tttgctgatg tgcgtactta
    35641 ttggagccca gaggctgtta aacgtgtaac gggacatact ttagagggtc gtgctgcagc
    35701 tggcttctta catctaatca actctggttc ttgtacattg gatggtacag gtcaagctac
    35761 tcgagatggc aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg aagtgcaggc
    35821 tatgcttgaa aatacagact tcccaccagc aaaccgcgaa tacttccgtg gaggaggatt
    35881 ctcaactcgt ttcttgacga agggggatat gccagtaaca atggtacgtc tcaatcttct
    35941 aaaaggggtt ggtccagtgc tacaaattgc agaaggttat acacttgaac ttcctgaaga
    36001 tgttcaccat actttagata atcgtacaga tccaggatgg ccaactactt ggtttgctcc
    36061 acgtttgaca ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata attggggagc
    36121 taatcacgga gccataacat atggacacat tggagcagac ttgattacct tggcttctat
    36181 gttgagaatt cctgtcaata tgcataatgt acctgaggaa gatatcttta gacctaaaaa
    36241 ttggtcctta tttggaacag aagatctaga atcagcagac tatcgtgcat gtcagttgtt
    36301 gggaccacta cataaataaa acttgtttat ataggaggtg aacttacgtc cctcctatcc
    36361 ttttaaaaag atttgttaaa caattcacaa ataattgaaa acgaatacaa aaagtaatat
    36421 aatgatgtta aatagatagc gcaaaggcgc aggaggaaaa ttatatggct acattttatg
    36481 ttccggcagt caaccttatt ggtaaaggtg ttgtaaatga agtgggtcct tatatcaagg
    36541 aacttggcta taaaaaggca cttttggtga cagataagta catcgaaggc agtgacattt
    36601 tacctaaggt tttaaaaccg ctagatacag aaggaatcga atatgtcatc tttagggatg
    36661 tagagccaaa ccctacttgt aaaaatgtca cagatggggt agctgctttg caagaacatg
    36721 gatgtgattt tatcatcagt cttggtgggg gttctccaca ggatgcagct agttgtattt
    36781 ctatcatggc tacaaatggt ggaagaccac aggattatga agggcttcat aagtctgcta
    36841 aaaaaggctt gccagttgtg gctatcaata caacggcagg aacttctgca gaaatcacta
    36901 ttaactatgt gattactgat gaagaacgca aggttaagat ggtaatggtt gacaagaata
    36961 gccttgctct tatctctgtc aatgacccgg aactcatgct ttccaaacct caagccttga
    37021 ctgctgctac tggtatggat gctctgactc acgctgttga agctttggta acacctggtg
    37081 cttatgatgt aaccaagaaa ctgtctattg gtgctattga gcttatcaag gaatatcttc
    37141 ctcgtgctgt agaaaatgga catgatattg aagcgcgtga aggtatggtc aatgccatct
    37201 tccttggtgg tatgagcttt aataatgctg gtcttggtta tgttcactca atggctcacc
    37261 aactcggtgc agtatataat ttaccacatg gtgtttgctg tgccatgttg ctaccagtta
    37321 tagaacgtga aaatgctaaa cgtgtaccag aagctttccg caatgttgcc aaagccttgg
    37381 gacttcatgt agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt gctgagattg
    37441 agaagctttc tgagacagta ggtattccta agaaactgac tgaacttggt attgaagaaa
    37501 aagatttcga ctttgaatac ctttctaaga atgccttgat tgatgcctgc gcaccaggaa
    37561 atccatttat gccaacctta gaagaaacga ttgcctttta taaagagtta ttttagcaag
    37621 agattggacg acaataggac aattcacctc taattattga catttcagga aaaatcgcag
    37681 taaaaacggc acagccttct ttaaatgtgc tataatacta gaaaaatact tgtggaggtt
    37741 ccattatggc aatatttttc atgatttttc tgattgtttg tgtgctccta ttggtgatag
    37801 tcacactgag tacagtttat gtggttcgtc agcagtcggt ggcgattatt gaacgctttg
    37861 ggaaatacca aaaggttgct aatagcggta ttcatattcg cttgcctttt gggattgact
    37921 cgattgcagc acggattcag ttgcgcttgt tgcaaagtga tattgtggtt gagactaaga
    37981 ccaaggacaa tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc aacgagcaga
    38041 gcgtgacaga tgcttactat aaactcatac gtccagaatc tcagattaaa tcttatatcg
    38101 aagatgctct tcgctcttct gttccaaaat taaccttgga tgaattgttt gagaaaaaag
    38161 atgagattgc ccttgaagtt caacaccaag tagcagaaga aatgaccact tacggctaca
    38221 ttatcgtgaa aaccttgatt accaaagtcg aaccggatgc agaagttaag caatccatga
    38281 atgaaatcaa tgcggcgcaa cgtaagcggg tcgcagcaca agaattggcg gaagctgaca
    38341 agattaaaat tgtcactgca gctgaagcag aagcagaaaa agaccgcctt catggtgtgg
    38401 ggattgccca acaacgtaag gcgattgtgg atggattggc agagtctatc accgaactca
    38461 aggaagccaa tgttggcatg acagaagaac aaatcatgtc tatcctcttg accaaccagt
    38521 atttggatac cttgaatacc tttgcctcta aaggaaatca aaccatcttt ttaccaaata
    38581 cgccaaatgg tgtggatgat atccgaacac aaatcttgtc agcccttcgc gctgagaaga
    38641 aataatagac taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta
    38701 tatttgagct gacttcgtca gttctatctg caacctcaaa acagtgtttt gagctgactt
    38761 cgtcagtctt atctactacc tcaaaacggt gttttgagca acctgtggct agtttcctag
    38821 tttgctattt gattttcatt gagtacaaag agcttggcaa caggctcttt ttgtattgcg
    38881 tttattaaga aaaacaaaaa acatagatat acatttaact aaaaattatt gtatgttacc
    38941 tcccttaatt aggaatgata agggaataac tagaaagatt tgtgaataca aactatttct
    39001 gatatacaaa atatacagta ataatgaatg atgggagatg ggatgaaaga atttcaattt
    39061 gagagaaagc agcgtttttc tttgaggcca tatgcaatag gagcttgttc ggtcttgcta
    39121 ggaacgagtt tattttttgc tggtatgggt gatcagcctg tacaggatac agaaacgagt
    39181 tcagcactaa tttcaagtca ttatttggat gagcaggatt tatctgaaaa gctgaaatct
    39241 gagttgcaat ggtttgaatt agaaaacaag cttttgaact tatgggagca ttaggttact
    39301 atgaaggatt tgttccttat gtttcaaatt aatacaaaaa ccaagctgaa gaagaagaca
    39361 aaccgctatc tgataaatat atttttgaaa aaatcttagg aaaaacatat gcagccttca
    39421 aaaaagatca aattaatgag cgtgtcgaga aattaggtaa gttaaaacct attacaataa
    39481 attacaacgg aaaatcagaa gtaattgata gtaaagaaaa attacaagag cttatgaata
    39541 aagccgttaa agacgaagtg gctcaaatat agtaaaatga aataagaaca ggacaaatcg
    39601 atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta ctattctagt
    39661 ttcaatatac tataaaatca ggcaatacca cggctaaaaa gtttgagttt atcgaaacac
    39721 cagtgcaaaa actgaaaaaa gcgatttata aagctcatct caaagattca gatgacttta
    39781 gaccagaaac atccacacca aatctttttg aaagctgttt gaagctttgt ccttgctttc
    39841 ttagttcata gatctgaact ttatcttcat aattcaattt cataataaaa caccccaaaa
    39901 gttagattta ttctgtctaa cttttggggt gcagttcatt aatcggtcga tttttttttg
    39961 tagaaacagt tgcctgatta agttgcaagt cgatagatgg cttcggcata aatatccata
    40021 gcacggtaca aatcttctag aacggcacat tcatttgcct gatgttctgt ctgcttcgct
    40081 cctgggaata aggcgccgaa ggctacacaa tttggcatgg tgcgagcaaa agtggcacca
    40141 ccggatgaaa tagcaggact gttatcgcca gtcttttctt ggtagatttg catcagtgtg
    40201 ctaacgagtt tactgtcttt tgcgacgtat agaggcgcta gatagtcaaa ctcttcgtag
    40261 cggagttggt agttttgtgc acatcttgta agcaactcta ctagttcttc cttgtcagct
    40321 aagacaggag tccgaatgtc aatacggatt tcagaacgtt catgattgat catgagacct
    40381 gcgacattaa aggataggtg accagaaggt tcatctgcta tatcaccaaa gatttgtctt
    40441 cctgtgccgt cttgacctgc ttgtgttgca agaaaactga gagcagggtg ttcttggaga
    40501 ggagcaagaa tggtagctag tcggatgaca gcattgatac cttgactagc atccttagca
    40561 tgctttggca ctccgagaac cgttacggtt tgttcagtgg tttggtaatc ataaccagct
    40621 tctttgagac cgttacaaac ctgttcatag aggggacctt ggtagttggc cttgtctggt
    40681 acaacgttaa aggcgcctcc tacttcaagc tctagttgat ccgatccagg gccataaagt
    40741 ttgacctgta gaagcccttt ttcagcatag gtcagaggaa aagatgagtc aggtgcaaag
    40801 cccatgctgg cctgttcttc gatggtattg tagcgtgcca tgcagcgcca gagggtttcc
    40861 tcatcggtac caaagataaa gcgtacgcgc tttttgaact gaataccttg gtccagcaag
    40921 ctttttactg catagagagc tgcgagcgaa gggcctttat catcttggac accacgtccg
    40981 aatacccagc cgtctttgat agttgcttca aatggcggtg tctgccaatc tgcttcatca
    41041 cctgatggaa caacatccaa atgacagaga atggccagaa gctctgctcc ctgaccgatt
    41101 tctgcatatc cgtaataacc tttagggtca agataggtag tgaaacctat gtcttgacaa
    41161 atctctaaag ttttttctag gacatcttgg attgcttgtc caaaaggtgt tccattttct
    41221 ccttcattga gtactgaagg ataggaaatc aaggttttta atgatataag aaattcatct
    41281 ttaacttgat ttgttatatc tattttcatg gaatcacctc actcactatt ttataggaat
    41341 ggaaggaagg ttccaaggag aagaagggcg atggtcacta caataatagc gactacgagt
    41401 ttgcccatga atttccacca agtaccaatg ttgatacgtc caagtgcaag agctcccatc
    41461 acaataccag atgttggtgc aatcaagttc aagacacctg aagcagattg gtaagcagtg
    41521 ataatcaagc taggacggac atttacaaat tctccaagtg gagccatgat acccatagtt
    41581 gcgctggcaa gaccagatga agatgggatc aagaatgaca taggtagata gaagatataa
    41641 gttacaacga taaagacttg tgaagataga ccgctcaagc cttctttacc ccagttgagg
    41701 attgtatcgg taatcatacc gtcgttcatg ataacttgaa taccacgagc aatcgctacg
    41761 atcaaggcaa cactgagcaa gtcagcagca ccattcatga aggaagagat aatcttatct
    41821 tctttaagac cataaataac accaatcagg atacccataa aggcaaagag catggcgcct
    41881 tctgggaagt accaagtacc tagtgcagaa gtagatgaac cgacaatatt accaataact
    41941 ggaagaccag tcaaccaagc attaaagtca tcaaaaatgg taacgccaag gtctgtccat
    42001 ggaatgaagc tcaataccat caagatgaat gtcaacacaa ataagaagag aactgatttt
    42061 tgtttgctgc taagtgtaga ttctacagat gaagattctt ctacgttaaa gtgtttcaaa
    42121 tcttctttgc gagtactata aaccagtgac ttagtcggat ctttttgaat cttatccgca
    42181 taacggtaaa caaaccaagt actaagagca gtcaaggtaa cccagaagat cagacgaagt
    42241 acgataccgt cccctgtacc aactcccgca gtcgctgaag caatacctgt cgcaaatgga
    42301 ttcagagtag atgccaaaca gccgatttga gaaccgagca aaataattgc aacaccagtc
    42361 aggctatcaa aaccaacggc catcataact ggcacaagga gtggatagaa ggccattgtt
    42421 tcttcaccca taccataagt tgtaccaccg agggcaaaca aaggcatcaa taccaaaatt
    42481 aacatttttt cgcggccctt atacttcttc acgatagagg caatccctac gtcaagagca
    42541 ccagttttgt tgacaatgcc aaggaaacca ccaaccataa ggatgaagaa ggctacatca
    42601 atcgctgcgc tcgtttcttt aatgagcgaa ccttcctctg gatgagtacc tagcatagcc
    42661 cgaatcggtg ccatgaggac atcccaaatc ccttgtggat tttgaggctg agtctcgtaa
    42721 ataccttcta taaaggcccc cgcagggata aaccaagtta gcactgccat aatagcaatg
    42781 attatcaata atacggtgta agatgaaggc atcttaaacc cttttttagc tttttcactc
    42841 atttgttttt cctcctgatg tctaacaaag tgtaaaaaac caactacttt cttaaataaa
    42901 catttaagaa aacgctttcc atctatattt gttttaccat attaaagtct aaaaaactag
    42961 tatcttttga aatattgtac atgttttcaa gaataatttc taatttgata taaagatact
    43021 agaaatagaa tacatcttat tagtaaaaca acttatcctt tttcaataat tgttccgctt
    43081 tcagattcaa tcaaggcgcc tagattttca agggaagtaa taactgcttt tccttctgga
    43141 cgaccattga caaaagcgat agctgcttct acttttggaa gcatgctacc tggtgcaaac
    43201 tgatcttgtt tgatatattc ttccagctgg gcaacattca catgttccaa tttttcctgg
    43261 tttggcttgt tgtagttaac aaatacataa tctacacctg tcaaaacgat gaagaggtct
    43321 gcatcaacca attctgccaa acgttgggaa gcgaagtctt tatcaataac cgcttcgaca
    43381 ccagtcaaat gtccattgtt ttctttgaca acgggaatac cgccaccacc tgcagctacg
    43441 acgacttgac cattatttaa aagagtacgg atggtttcaa tttctttgat gtcaacaggt
    43501 tttggtgagg caacgacctt acgccagcca cggccagcat cttccttgaa agtcgctccg
    43561 ctcttttcgg cttctgcttt tgcttcttct tctgaataga aaggaccgat tggtttactc
    43621 aagttaacaa aagctggatc atttttatct acgacaactt gcgttacaac agaggcaaca
    43681 tttttttcga tgccttcatc caagagagca ttttgcaaag catttttcaa ccagaaaccg
    43741 atgctacctt ctgtcatagc gacaagtgag tcgagtggga aggcagggtt cttttcagag
    43801 tctgatgcca aatgttggag caagagattc ccaacttgag gtccattacc gtgagtgata
    43861 atcagatcat ctccattttt aatcaatttt acaagatgct tagctgtttc aactaaagct
    43921 tcttgttgag cctttgctga tgggtcagaa gaaagaatcg catttcctcc caaagctact
    43981 acaattttac gatttgccat aaattctcct ttatcacact caatagaatg cgtttagatt
    44041 tcaatttaat gatttttcac atattttata agaaataata gattaccatt acataaaaga
    44101 ggaccggact aaagctatta gtcgcagccc tcatagctgt tggtagacgg tttattatct
    44161 aaaattatac tttaggaata taaaggttac caagtgtagc agccataaca gctttgatag
    44221 tgtgcatacg gttttctgct tgatcgaagt ggcgagcgta cttgctgcgg aagacttcgt
    44281 ctgttacttc catttcttct acaccaaatt tttcagcaac gtctttacca taaacagtgt
    44341 gagtatcgtg gaatgctggc aagcagtgta ggaagatcaa gttttcattg cctgcttttt
    44401 taactaagtc catattgact tggtaaggtt taagaagagc tacacgttct gcgaatttgt
    44461 cttcttcacc cattgatacc caaacgtctg tgtaaagaac gtctgcatct ttaactgctt
    44521 catcagcatc ttcagtgatg agaacatgtg cgccactttc tttagcaaat ccttctgcca
    44581 attcaacgat ttctttttct gggaagagtt cttttggtga gaagatgtga acattgacac
    44641 caaggatagc acctgttacg agcaagctgt tggcaacgtt gttacgtcca tcaccacagt
    44701 ataccaatgt caagccttcc aagcgaccga agttttcttg aacagtcaag tagtcagcga
    44761 gcatttgagt tgggtgccat tcgtcagtta gaccgttcca tactggaacg cctgagaatt
    44821 ctgccaattc ttcaaccata cgttggctga atccgcggaa ttcaatcccg tcaaacatac
    44881 gtcccaatac tttagcagta tcttcagtag attctttttt acccaactga atatcatttg
    44941 ctccgaggta ttctgggtga gcaccaaggt cgatagccgc agttgtaaag gctgcacgag
    45001 tacgagtaga tgttttttca aataggagag cgatattctt gccagcaagg tagtggtgtt
    45061 gaatattgcg ttttttcaaa tctttcaagt gagctgaaag accaataagg tattctaact
    45121 ctgcacgggt aaagtctttt tctgctaaga agctgcgtcc ttggaatact gaatttgtca
    45181 ttttattatt tcctctttct attttttaca ttttctattg acgaataccg aacagcgatt
    45241 acacttcttc acgttcaaat ggcatagaca tacaacgagg tccaccacgg ccccgaacca
    45301 attcacttcc gcgaatctta atcaagcgaa gcccgtattc ttccaaaatc ttattggtca
    45361 cggtattgcg gtcataaaca actaccacac caggtgcgat ggtcaaagtg ttagaaccgt
    45421 cgttccattg ttcacgcgca gctgctacga tattgccacc accgcaacga atcaaatgaa
    45481 ctttttctac accaaggttt tgagcaagaa gttcagctaa gtcacctttc tcttcaacga
    45541 ttttaagttt ttcgttttcg taagtaactg agtaaacgtg aaggtcgcct tcgatttctg
    45601 ggtgaatagt gaacttgtca tagtctacca tagtgaagac agtatccaag tgcatgaatt
    45661 tacggttgtt agcaaattca aaggccaaaa ctttcttgaa gccaacattt ttcttgaaga
    45721 tgttgaccaa aagtttttcg atagaagctg cgtctgtacg ttgagagata cctactgcaa
    45781 ggacgtcttt agaaagaact agctcgtctc caccttcgat acgcgtatct tcttcacggt
    45841 tgtagaccaa atccactttt ccgccataga ttgggtggta tttgaagata tacttaccgt
    45901 agagtgtttc acggttacga gtgtctgcaa acatgtggtt aagcgatacg gcgtttccaa
    45961 ttgttgcaaa tgggtcgcga gtgaaataga ggtttggcat cgggtcaatt gcaaatggat
    46021 aatctgattc aactaagtca gttagatctt tagcttcgtc aggaatttct ggcaattcaa
    46081 ctttttgaat cccagccatt gttttttcaa ccaattcttg gttgtccttg atgccgtgaa
    46141 gcaattcacg aatagcaacc ttagtttgac gatcacggat gttggcttcg tctaagtatt
    46201 cctcgataaa ttgatcgcgg atttctggag aggtcaatga ttcagcagcg agttgttcta
    46261 ggtagagaac ctcaattcct tcatcgcgaa gagcttgggc aaatgcatca tgttcttttt
    46321 gagcatcttc caagaaagga atatcatcaa aaagaagcct ttcaagatag tccggcaaca
    46381 agttttctaa ctccttgcct ggacggtgca acataacttt tttcagtttc ccaatttctg
    46441 agaagacctg aattggatga gaagacatgt attttcctcc ttaaaaattt tgacttggca
    46501 ccattttggg taccgcttac atgtatgtta taacgcaatt cctaggtaat gtcaatggct
    46561 ataatttctc ggaaaataat ataaattatg atgtttagca caattttatg ttattataca
    46621 taacatagga tagaatacat agatacaaat gcataaactt ctataaaaag gatataaaat
    46681 ttttttaaaa aatttttcaa aaaatataca aatgaccaaa aagtgtccaa ttatcatctg
    46741 gttatcactt ggatctgtat aaagagaaat gtttgtgtga aaggataaaa agatgcaaca
    46801 ttcttttgaa gatagatttt ggagaagcat ttcttgttca attgtacaaa ttatagaatc
    46861 ttttctgagt atttaggaag agataattat cttattgacc ctctttttat tttttgttat
    46921 agtcgacgag gtgatagctt agaataatca cttattcaca atctgtggaa aagtctggag
    46981 agtgaatggt cttcacacaa tgacctgaaa gaagcctgag aataattatg gagagtagca
    47041 ttctgagagg tgttagcaga atcatatgac agagctgttt gaagagggaa tattgaggag
    47101 aaaaatcctg agcctaccag ttggagttgg aaagagctgg ctgttagatc atggtttatt
    47161 atccacaacc tgtggataac cttgtgaaca agagaagttg ctaaagaagg agatatataa
    47221 cgatgaagaa aatcaaaccg catggaccgt taccaagtca gactcagcta gcttatctgg
    47281 gagatgaact agcagctttt atccacttcg gtcctaatac cttttatgac caagaatggg
    47341 ggactggaca ggaggatcct gagcgcttta acccgagtca gttggatgcg cgtgagtggg
    47401 ttcgtgtgct caaggaaacg ggcttcaaaa agttgatttt ggtggtcaag caccacgatg
    47461 gctttgtcct ttatccgaca gctcacacag attattcggt taaggtcagt ccttggagga
    47521 gaggagaggg cgacttgctc cttgaagtat cccaagctgc cacagaattt gatatggata
    47581 tgggggtcta cctgtcaccg tgggatgccc atagtcccct ctatcatgtg gaccgagaag
    47641 cggactacaa tgcctattat ctggctcagc tgaaggaaat cttatcaaat cctgcctatg
    47701 gaaatggagg gaaatttgct gaggtttgga tggatggtgc cagaggagag ggcgcgcaaa
    47761 aggttaatta tgaatttgaa aaatggtttg aaaccattcg tgacctgcag ggcgattgct
    47821 tgattttttc aacagaaggc accagtatcc gctggattgg caatgaacga gggtatgcag
    47881 gtgatccact gtggcaaaag gtgaatcctg ataaactagg aacagaagca gagctggact
    47941 atcttcagca cggggatccc tcgggcacga ttttttcaat cggagaggca gatgtttcca
    48001 tccgtccagg ctggttctac catgaggatc aggatcctaa gtctctcgag gagttggtcg
    48061 aaatctactt tcactcagta gggcgaggaa ctccactctt gcttaatatt ccgccgaatc
    48121 aagctgggct ctttgatgca aaggatattg aacgacttta tgaatttgcg acctatcgca
    48181 atgagctcta taaagaagat ttggctctgg gagctgaggt atctggttca gctctttccg
    48241 cagactttgc ttgtcgccat ttgacagacg gccttgagac cagctcttgg gcaagcgatg
    48301 cagacttgcc catccagtta gaactcgact taggttctcc taaaactttt gatgtaattg
    48361 agttaagaga agatttgaag ctagggcaac gaatcgctgc ttttcatgtg caagtagagg
    48421 tggatggtgt ctggcaggaa tttagcaggg gcttcacagt tggtcataag cgcctcttgc
    48481 gaggtccgct agtagaggca caaaaggtgc gcgtgatgat taccgaggca caatctattc
    48541 ctgtattgac caagatttcc ctttataaaa ctcctggatt atcaaaaaaa gaagttgttc
    48601 aggaactagc atttgcagaa aaaagcctag ctgtggcaaa gggagaggct cttcatttta
    48661 ggattgaacg tagtgaaagt agctcctctt tagaggctaa gatttcgatt caaccgggga
    48721 caggtgtcca tggtgtcgcc tatcaggacg agatttatgt ccttcaattc caagcagggg
    48781 aaagcaaaaa agatttgcat ctaccaaccc tgtatttcgc aggagataaa accttggatt
    48841 tctatctgaa cctaacggtg gatggtcagc ttgtggatca acttcaagtc caagtttcat
    48901 aaaagaagaa cctttgcgcg atgcaaaggt tcttttggtt attagtgact tggtagccag
    48961 ctgagggtga aagttagttg ttcagctttt aagaggtctt ggtgttgaat agttgatacg
    49021 agtgttttgt tcagtcggca ttctttgaca aagttaaaat ggttgtggtt ttgtttagta
    49081 tggatatcca gccatttatc ttctttagct aggtagactc gtagatggtc aaagagaggg
    49141 attccgaggt catagcttgg ttttcctgga caggttggat aaaatccgag agctgaccag
    49201 atgtaccaag cagagagact accattgtct tcatctccag gataggcttc ccaacttggg
    49261 tgaaaagctt tctgacggag cgtcttgatg agaagggcag tgtagtcagg gtaatcgctg
    49321 tagcggaaga gataaggaat gtggaaacta ggctggttgg aaatggctat ttgtccaaaa
    49381 ggagcagtag ccatctcgct catttcgtga atttcgtaac catagcctgt tgtttcaaag
    49441 aggggagcat cttgacaggc tttcaaaaga tagttgctaa aggtttcttt tccacccata
    49501 agttggatta agccagggat gtcgtggaga acgcctaaag tagcttgaat ggcagagcat
    49561 tcagcgtagt ctcgccccca actataagga gagaagtcag ggtgaaagtt tccttgattg
    49621 tctcgtgctc gcatgtaacc tgtctcagcg tcaaatagct ggcggtaatt ttgtgaagca
    49681 gccttgtagg tttcagcgat ttctatgttc tctagttttt tggcacagct ggcgatacaa
    49741 aagtcactat aggcatagtc tagagtatgg ctaacacttt cgtggtggtc ggtagagagg
    49801 taacctcgtt cttggtattg ggctagtccg tggcggccat tgatgccgag agggtcggct
    49861 ttgctggctg tttcgagcat ggcttggaag agttctcctt ctaggtcagg ggccatgtcc
    49921 ttgcaggcgc tatctgcgat aataccgtct aaaagtgtac ctggcatcat accccgttca
    49981 tctggagcca gccattttgg aaggaaacca gtatcgcggt agctattgag gaaaccttct
    50041 aaaaagcgtt gatagtgctc cggtatgata agggcaaaga gggggaaggt ggtgcggaag
    50101 gtatcccaga aaccattgtt gctaaagagg acaccaggct tgacagtacc agtagccaga
    50161 tccatgtgga tggcttgccc tgactcatca acctcataaa aagtctgtgg gaagaggaag
    50221 agtctgtaga ggcagtggtc aaagaaggtt cggtcagcct ctcctatctc tataatgtca
    50281 aaacgatgga ggagattttc ccaatccgct tgggcacttg atttacagct atcaaaatct
    50341 tcttgaggta gattaagcag tgcttgagaa ggagagatga aagaagtggc tagttgcatc
    50401 tcggtttgac tacttgctaa gtcaattcgc cagtccccag cttcttggct gatagcaaga
    50461 atatccgtgt tcatttgcag ggcagtgaac atcgttagcg aatttttgtt ggtttcagtt
    50521 ttaccttctt gtcgcagggc aagagttcgc ttatctactt gctctactgt cagttcatct
    50581 gctgcgtgaa gatagaggga gagggctttg ccttgctttt gcttcaaacg aatagaagca
    50641 ccgtagcaag tcggtgtgag ctgggtttca atctgatagc gcagggagaa aatctttaga
    50701 taatgaggtt ggaaagaggc cttatcccta tcataggaag attggcggtg aaagagactg
    50761 tctcccccaa gctgacctgt gacaggtgtc agaaggagcc aagagtagtc cccaatccaa
    50821 ggactgggct ggtgagttaa tcgaatcccc tgaaagatag gcagatgcgg atcaaaaaac
    50881 caagatccat cctggtcact ggtctggggc acaaagtaat tcatcccaaa aggcacgcct
    50941 gtgtatggca gggtatttcc ccgagaaaag gcatgcttgt tggtagttcc aaagcgggta
    51001 tcgatggttt caagtagtgg tttcatagtc tttcctttag ctgtttttct acattatatc
    51061 agaaaaagag ggcctttaga aaaggagttt caaaaataac tattttgtag aaaaatgact
    51121 atcatttgtg tatgtatttt ctgtctcaaa agctatatac tgaacatgaa acttgtttga
    51181 aagagggaat tgcacgatga tttattcgaa agaaattgtt agagaatggc tagatgaagt
    51241 agcagagcgg gctaaggacc atccagagtg ggtggatgtt ttcgagcgtt gctacaccga
    51301 taccttggac aatacggttg aaatcttaga agatggttca acttttgtct tgactgggga
    51361 tattcctgcc atgtggcttc gagattcgac agcccaactc agaccctacc ttcatgtagc
    51421 taaaagagat gccctcctgc gtcagaccat tgcaggtttg gtcaaacgtc agatgacctt
    51481 ggtactcaag gatccctatg ctaactcctt caacattgag aagaactgga aagggcacca
    51541 cgagactgac cacacagacc ttaacggctg gatctgggag cgcaagtatg aggtggattc
    51601 actttgctat cctttgcagt tggcttatct cctctggaaa gagactggcg agactggtca
    51661 gtttgatgag acttttgtcg cagcgactaa ggaaattctc catctatgga cagttgaaca
    51721 agaccacaag aactctcctt atcgttttgt ccgagatacg gaccgtaagg aagacacctt
    51781 ggtaaatgat ggctttggac ctgactttgc agtgacaggt atgacttggt cagcctttcg
    51841 tccgagtgat gactgttgcc agtatagtta cttgattccg tcaaatatgt ttgctgtagt
    51901 agtcttgggt tatgtgcaag aaatcttcgc agcattaaac ctagctgata gcgagagcat
    51961 tattgctgat accaagcgtc ttcaggatga aatccaagaa ggaatcgaaa actacgctta
    52021 caccaccaac agcaagggcg aaaagattta cgcttttgaa gtggatggcc taggaaatgc
    52081 cagcatcatg gatgatccaa atgtaccaag tctactagct gcgccctatc tgggctactg
    52141 ttcggtcgat gatgaagtgt atcaagctac tcgccgtacc attttgagct ctgaaaatcc
    52201 atacttctac caaggagaat acgctagcgg tctcggaagt tctcatacct tctatcgcta
    52261 tatctggcca atcgcccttt ctatccaagg attgacaaca agagataagg cagagaaaaa
    52321 attcttgctg gatcagctgg ttgcctgcga tggtggtaca ggtgtcatgc acgaaagctt
    52381 ccacgtagat gatccgaccc tctactctcg tgaatggttc tcctgggcta acatgatgtt
    52441 ctgtgagttg gtcttggatt acttggatat ccgctaaggg gctcgcttta gctcaaccga
    52501 ttcttatcag aatcacaagt ttacatttaa aacgttaaaa tttaaattta gaatgaggtt
    52561 ttacttcatg gaaaatgttg ttgtacatat tatctcacat agtcactggg accgtgagtg
    52621 gtacttgcct tttgaaagcc atcgtatgca gttggtggaa ttgtttgaca atctctttga
    52681 tctctttgaa aatgaccctg agttcaagag tttccacttg gatggacaaa ctattgtcct
    52741 tgacgactac ttacaaattc gccctgaaaa tcgtgacaag gtccaacgct acattgacga
    52801 gggcaaactt aaaattggtc ccttttacat cttgcaggat gactacttga tctccagtga
    52861 agccaatgtc cgcaatacct tgattggtca acaagaagct gccaaatggg gtaaatcaac
    52921 ccagattggc tactttccag atacctttgg aaatatggga caagcgcctc aaattcttca
    52981 aaaatcaggc attcacgtgg cggcctttgg tcgtggtgtg aagccgattg gatttgacaa
    53041 ccaagtcctt gaagatgagc agtttacatc ccagttttca gaaatgtact ggcagggtgt
    53101 ggacggtagt cgtgttttag gtattctctt tgccaactgg tacagtaatg ggaatgaaat
    53161 cccagttgac aaagatgagg ccttgacctt ctggaaacaa aaattgtcag atgtgcgtgc
    53221 ctacgcttcg accaaccaat ggttgatgat gaacggctgt gaccaccagc ctgtccagaa
    53281 aaatctgagc gaagccattc gtgtggcaaa tgaactcttc ccggatgtaa tctttgttca
    53341 tagttctttt gatgaatatg ttcaagctgt agaaggtgcg cttcctgaac acttatcaac
    53401 tgttacaggt gagttgacca gtcaggaaac agatggctgg tacacacttg ccaacacttc
    53461 ttcatcccgc atttacctaa aacaagcctt ccaagaaaat agcaacctcc tagagcaagt
    53521 ggtagaaccc ttgactatta tcactggtgg acacaaccac aaggaccagt tgacctatgc
    53581 ttggaaaaca cttttgcaga atgcgccaca tgatagtatc tgtggctgta gcgtggacga
    53641 agttcaccgc gagatggaaa cgcgttttgc caaggtcaac caagtaggaa actttgttaa
    53701 aagtaatttg ctcaacgagt ggaagggtaa aattgctacg gataaggctc aaagtgacta
    53761 tctctttact gtcattaaca caggcttgca tgataaggtc gatactgtca gcacagtgat
    53821 tgatgtggcg acttgtgatt tcaaggaatt gcacccaaca gaaggctaca aaaagatggc
    53881 tgctcttatc ttgccaagtt accgtgtgga ggacttggat ggtcgtcctg tagaggctac
    53941 aatcgaagac ctcggagcta attttgaata cgatttacca aaagacaagt tccgccaagc
    54001 tcgtattgct cgacaagtgc gcgtgaccat tccagttcac ctagcaccgc tttcttggac
    54061 aaccttccaa ttgctggaag gagaacaaga acaccgtgag ggtatttacc aaaacggagt
    54121 gattgataca ccattcgtaa cggtgagtgt ggatgacaac atcacagtct atgataagac
    54181 aactcacgaa gcctatgaag actttatccg ctttgaagac cggggtgaca tcggaaacga
    54241 gtatatctat ttccaaccaa aaggaacaga gccaatcttt gcagagctta aggaccacga
    54301 ggtcttggaa aacacagatc gctatgctaa aatcttgctc aaacatgaat tgaccgtgcc
    54361 tgtcagtgcg gatgaaaagc tagaagaaga gcaacaaggt atcatcgagt ttatgaagcg
    54421 tgaggctgga cggtcagaag aattgacaaa cattcctctg gaaactgagt tgactgtctt
    54481 cgttgacaat ccacaaatcc gcttcaagac tcgctttact aacactgcca aggatcaccg
    54541 tatccgtctc ttggtcaaga ctcataacac gcgtccaagc aatgattctg aaagtatcta
    54601 tgaggtggtg acacgaccaa acaaaccagc tgcttcatgg gaaaatcctg aaaatcctca
    54661 acaccaacaa gcttttgtca gtctgtatga cgatgaaaaa ggggtgactg tatccaacaa
    54721 gggattgaat gaatacgaaa tccttgggga taacaccatt gccgtgacca ttttgcgtgc
    54781 atcaggtgag ctaggtgact ggggctactt cccaacgcca gaagcacaat gcttgcgtga
    54841 gtttgaagtc gaatttgcga ttgaatgcca ccaagcccaa gaacgcttct cagcctatcg
    54901 tcgtgccaaa gccttgcaga caccgtttac cagccttcag ctttctagac aggaaggaag
    54961 cgtggttgcg actggtagcc tcttgagcca ttctgttctc agcataccgc aagtttgtcc
    55021 aacagccttt aaagtggcgg aaaatgaaga aggctatgtc ctccgttact ataatatgag
    55081 tcaagaaaat gtgcgcatat cagaacatca acaaaccatt cttgacttac ttgagcgacc
    55141 atatccagtt cattcaggac tattggctcc acaagagatt cgtacagaat tcatcaaaaa
    55201 agaagaaatt taatttcaaa aagtaaacat caaaagaaag gaggggcgaa aaggtaagaa
    55261 ctaactgctg attcgcccct ttttatggta aaaacaatga ccattgcaac gattgatatc
    55321 ggagggactg ggattaagtt tgccagtctg actcctgatg ggaaaatact ggataagaca
    55381 agtatttcaa cgcctgaaaa cttggaggat ttactagcgt ggctagatca acgcttgtca
    55441 gaacaggatt acagtgggat tgctatgagc gttccaggtg cggtcaatca agagacaggt
    55501 gtgattgatg gcttcagtgc ggtgccctac atccatggct tttcttggta tgaggcgctt
    55561 agctcttatc agctacctgt ccatttagaa aatgatgcca actgcgttgg actcagtgaa
    55621 ctactagctc atccagagct tgaaaatgca gcctgtgtcg tgattgggac agggattggc
    55681 ggagccatga ttatcaatgg tagacttcat cgaggtcgcc acggcttggg tggagaattt
    55741 ggctacatga caacccttgc ccctgctgaa aaacttaata actggtcgca actagcatca
    55801 actgggaata tggtacgata cgtgattgaa aaatctggtc atactgattg ggacggtcgc
    55861 aagatttacc aagaggccgc agctggtaat gctctttgtc aagaagccat tgagcgcatg
    55921 aaccgcaatc tggcgcaagg cttgctcaat atccagtatc tcatcgatcc agatgtcatc
    55981 agtctgggtg gctctatcag tcaaaatcca gattttatcc aagatgtcaa gaaggctgtt
    56041 gataactttg tcgataccta cgaagaatac acggtcgcac cagttatcca gacctgcacc
    56101 tatcacgcag atgccaatct ctacggtgcc cttgtcaact ggctacagga ggaaaagcaa
    56161 tggtaagatt tacaggactt agtcccaaac aaacgcaagc tattgaggtt ttaaaaggtc
    56221 atatttctct accagatgtg gaagtggctg tcactcagtc tgaccaagcc tctatctcta
    56281 tcgtgggtga ggaaggtcac tatcaattga cctaccgcaa acctcaccaa ctttatcgtg
    56341 ccttatcctt gttggtaaca gttctagcag aagctgataa agtagagatt gaggaacaag
    56401 cagcttacga agatttggct tacatggttg actgttctcg aaatgcggtg ctgaatgtgg
    56461 cttctgccaa gcagatgatt gaggtcttgg ctctcatggg ctactcaacc tttgagcttt
    56521 acatggaaga cacttaccag attgaagggc agccttactt tggctatttc cgtggagctt
    56581 attcagcaga ggagttgcag gaaatcgaag cctatgctca acagtttgac atgacctttg
    56641 taccatgcat ccagaccttg gcccacttgt cggcctttgt caaatggggt gtcaaggaag
    56701 tgcaggagct ccgtgatgta gaggacattc ttctcattgg cgaagaaaag gtttatgacc
    56761 tgattgatgg catgtttgcc acgttgtcta aactgaagac tcgcaaggtc aatatcggga
    56821 tggacgaagc ccacttggtt ggtttgggac gctacctgat tttgaacggt gttgtggatc
    56881 gtagtctcct catgtgccaa cacttggagc gcgtgctgga tattgctgac aaatatggtt
    56941 tccactgcca gatgtggagt gatatgttct tcaaactcat gtcagcggat ggccagtacg
    57001 accgtgatgt ggaaattcca gaggaaactc gtgtctacct agaccgtctc aaagaccgtg
    57061 tgactctggt ttactgggat tattatcagg atagcgagga aaaatacaac cgtaatttcc
    57121 gcaatcatca caagattagc catgaccttg catttgcagg gggagcttgg aagtggattg
    57181 gctttacacc tcacaaccat tttagccgtc tagtggctat cgaggctaat aaagcctgcc
    57241 gtgccaatca gattaaagaa gtcatcgtaa cgggttgggg agacaatggt agtgaaactg
    57301 cccagttctc tatcctatca agcttgcaaa tctgggcaga actcagctat cgcaatgacc
    57361 tagatagttt gtctgcgcac ttcaagacca atactggtct aacggttgag gattttatgc
    57421 agattgacct tgccaacctc ttaccagacc taccaggcaa tctcagcggt atcaatccca
    57481 accgctatgt tttttatcag gatgttcttt gtccgatact tgaccgacac atgacacctg
    57541 aacaggacaa accgcacttc gctcaggctg ctgagacgct tgctaacatt aaagaaaaag
    57601 ctggaaacta tgcttatctc tttgaaactc aggcccagtt gaatgctatt ttaagtagca
    57661 aagtagatgt gggacgacgc attcgtcagg cctaccaagc ggatgataaa gaaagtttac
    57721 aacaaatcgc cagacaagaa ttaccagaac ttagaagcca aattgaagac ttccatgccc
    57781 tctttagtca ccaatggctg aaagaaaaca aggtctttgg tttggataca gttgacatcc
    57841 gtatgggcgg actcttgcaa cgcatcaaac gagcagaaag ccgtatcgag gtttatctgg
    57901 ctggccagct tgaccgcatc gacgagctgg aagttgaaat cctaccattt actgacttct
    57961 acgcagacaa ggatttcgca gcaactacag ctaaccagtg gcataccatt gcgacagctt
    58021 cgacgattta tacgacttaa tactcttcga aaatctcttc aaaccacgtc agcttccatc
    58081 tacaacctca aaacagtgtt ttgagcagcc tgcagctagc ttcctagttt gctctttgat
    58141 tttcattgag tataaaaaca agaacacctt gcttggcgca gggtgtttcg cgtgaaacag
    58201 aagaattatc tggtttcaaa tgctacagtt agacaaactt atgataaaat agcagaaagt
    58261 gaatgtttcc taagagcaat tctatcgatg agcaattgga ggtattatgc tacacttaaa
    58321 attagtaaaa caagaaatag aagctgaaaa gccagcatct gtagaagctt ggatcatttc
    58381 cgtcaaattt taaaaaggtt gctaccgaca tatatagatt ccaaaaacaa aaacgttagc
    58441 ggaactagca gatgtgattt tatggagttt tgattttgca aatgatcatg ctcacgcatt
    58501 tttcatggat aatgttgagt ggagtcatgc agattcttac tttcttagct ttgttagtga
    58561 cgatgttgaa gaacgttaca cagaaaatgt ctatctggat agcctaagtg tcaaacaaaa
    58621 atttaagttt attttcgact tcggtgatga atggcgtttt gaatgccaag tgctgagaga
    58681 aatcgagaca gaggacgaag aagcttatct cgtacgttcg gttggaacgt cgctagaaca
    58741 atatccagat tatgatggtt ttgactatga agaatggtaa aattgaaatc taaaaaacaa
    58801 ttggaatcag tctgtgtagg cttagtattt caatagactt cctgcaaaac tagaatccta
    58861 gttcatgatt gataatacca gcactcaaat tcattcgtaa tccaaagcgt ttacgatgat
    58921 ttcgataggt tgttgaaaac attttaaacg tttttacttt ggcaaggatg ttctcaacct
    58981 tgcttctatc cttagatagt gcatggttat aggttttatc ttcaactgtt agtggcttga
    59041 gtttgctgga tttacgtgga atttgtgctt gaggatatat cttcatgagc ccttgataac
    59101 cactgtcagc caagatttta ccagcttgtc cgatatttct gcgactcatt ttgaacaact
    59161 tcatatcatg acaatagttc acagtgatat ccaaagaaac aattctccct tgacttgtga
    59221 caatcgcttg agccttcata gcgtggcatt tctttttacc agaatcattc gctaattctt
    59281 tttttagggc gattgatttg tacttccgtc gcatcaatca ttaccgtgtc ctcagagctg
    59341 agaggagttc ttgaaatcgt aacaccactt tgaacaagag ttacttcaac ccattggctc
    59401 cgacggatta agttgctttc gtgaatacca agatcagccg caatttcttc ataagttcga
    59461 tattctcgca catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt
    59521 cgtccacctt ttgcgtgttt aagttgataa gctgttttta atacagctaa catctcttca
    59581 aaagtggtac gctgaacacc aacaaggagc ttaaatcgtg catcagttag ttgtttactt
    59641 gcttcataat tttgtttcgc agggagtcta ttgactcttt ggtaggtgtc aatgtttttt
    59701 tcatctatcc cgagaattat tttcccgcca tttgtatttg caaatgctga gtaggtttcc
    59761 cagaaagact ctggaagatt gtttttagct tttttgtatt ctaaatcaac cccttcaaat
    59821 tttaagtcca tatttttcct ttacatctgt tttttgtggt tctggtattt gttcaagttg
    59881 agtgataata tagcgaattg aatttcgaga gtttttactc agttaatttt tcttgactta
    59941 aaatttaaaa atgatatact gtgtttatgg agagatgaca atttataaaa
//
LOCUS       DAVLTG010000007        59090 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLTG010000007 DAVLTG010000000
VERSION     DAVLTG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.007"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(134..475)
                     /locus_tag="VYN12_000445"
     CDS             complement(134..475)
                     /locus_tag="VYN12_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1414886.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            599..1450
                     /gene="rgg"
                     /locus_tag="VYN12_000446"
     CDS             599..1450
                     /gene="rgg"
                     /locus_tag="VYN12_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1414887.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRKTPDS"
     gene            1641..2888
                     /locus_tag="VYN12_000447"
     CDS             1641..2888
                     /locus_tag="VYN12_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1414888.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSAFILFLGKSKLSLSISSADGEKLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQVCVLLAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            2966..4255
                     /locus_tag="VYN12_000448"
     CDS             2966..4255
                     /locus_tag="VYN12_000448"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1414889.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            4246..4326
                     /locus_tag="VYN12_000449"
                     /pseudo
     CDS             4246..4326
                     /locus_tag="VYN12_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4398..4745
                     /locus_tag="VYN12_000450"
     CDS             4398..4745
                     /locus_tag="VYN12_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414890.1"
                     /translation="MIDKVVRNLLLTFFLCKMTKIINFLTTILVKKKKMCYNVSKLRE
                     KKKGNAEMSRLLQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQ
                     RIEDIQTVEFDGE"
     gene            4755..4961
                     /locus_tag="VYN12_000451"
     CDS             4755..4961
                     /locus_tag="VYN12_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1414891.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            4961..5158
                     /locus_tag="VYN12_000452"
     CDS             4961..5158
                     /locus_tag="VYN12_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414892.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            5161..5895
                     /locus_tag="VYN12_000453"
     CDS             5161..5895
                     /locus_tag="VYN12_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1414893.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            5907..6548
                     /locus_tag="VYN12_000454"
     CDS             5907..6548
                     /locus_tag="VYN12_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1414894.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            6566..6796
                     /locus_tag="VYN12_000455"
     CDS             6566..6796
                     /locus_tag="VYN12_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414895.1"
                     /translation="MKRVILVAVIQAVILFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            6832..6912
                     /locus_tag="VYN12_000456"
                     /pseudo
     CDS             6832..6912
                     /locus_tag="VYN12_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7193..8956
                     /gene="aspS"
                     /locus_tag="VYN12_000457"
     CDS             7193..8956
                     /gene="aspS"
                     /locus_tag="VYN12_000457"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1414896.1"
                     /translation="MKRSMYAGRVREEHIGQEIALKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            8934..9875
                     /locus_tag="VYN12_000458"
     CDS             8934..9875
                     /locus_tag="VYN12_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1414897.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(9911..10159)
                     /locus_tag="VYN12_000459"
     CDS             complement(9911..10159)
                     /locus_tag="VYN12_000459"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414898.1"
                     /translation="MKIKVQTRKLAAGCSKHGFEVADRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSSKHGFEVADRIDEVSNIYTARRR"
     gene            complement(10301..11287)
                     /locus_tag="VYN12_000460"
     CDS             complement(10301..11287)
                     /locus_tag="VYN12_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1414899.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(11297..12097)
                     /locus_tag="VYN12_000461"
     CDS             complement(11297..12097)
                     /locus_tag="VYN12_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1414900.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(12350..13192)
                     /locus_tag="VYN12_000462"
     CDS             complement(12350..13192)
                     /locus_tag="VYN12_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1414901.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(13194..14486)
                     /locus_tag="VYN12_000463"
     CDS             complement(13194..14486)
                     /locus_tag="VYN12_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1414902.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(14597..15868)
                     /locus_tag="VYN12_000464"
     CDS             complement(14597..15868)
                     /locus_tag="VYN12_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1414903.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            16418..17935
                     /gene="malQ"
                     /locus_tag="VYN12_000465"
     CDS             16418..17935
                     /gene="malQ"
                     /locus_tag="VYN12_000465"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1414904.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            17961..20219
                     /gene="glgP"
                     /locus_tag="VYN12_000466"
     CDS             17961..20219
                     /gene="glgP"
                     /locus_tag="VYN12_000466"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1414905.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(21264..21836)
                     /locus_tag="VYN12_000467"
     CDS             complement(21264..21836)
                     /locus_tag="VYN12_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414906.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(22635..23483)
                     /locus_tag="VYN12_000468"
     CDS             complement(22635..23483)
                     /locus_tag="VYN12_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1414907.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23635..23913
                     /locus_tag="VYN12_000469"
     CDS             23635..23913
                     /locus_tag="VYN12_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414908.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            23915..25978
                     /locus_tag="VYN12_000470"
     CDS             23915..25978
                     /locus_tag="VYN12_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1414909.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(26056..27312)
                     /locus_tag="VYN12_000471"
     CDS             complement(26056..27312)
                     /locus_tag="VYN12_000471"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1414910.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            27454..29919
                     /locus_tag="VYN12_000472"
     CDS             27454..29919
                     /locus_tag="VYN12_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1414911.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            29984..30895
                     /locus_tag="VYN12_000473"
     CDS             29984..30895
                     /locus_tag="VYN12_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1414912.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            31125..31823
                     /gene="dapD"
                     /locus_tag="VYN12_000474"
     CDS             31125..31823
                     /gene="dapD"
                     /locus_tag="VYN12_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1414913.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            31891..33021
                     /locus_tag="VYN12_000475"
     CDS             31891..33021
                     /locus_tag="VYN12_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1414914.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            33033..33572
                     /locus_tag="VYN12_000476"
     CDS             33033..33572
                     /locus_tag="VYN12_000476"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1414915.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            33556..34233
                     /locus_tag="VYN12_000477"
     CDS             33556..34233
                     /locus_tag="VYN12_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1414916.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(34300..35199)
                     /gene="galU"
                     /locus_tag="VYN12_000478"
     CDS             complement(34300..35199)
                     /gene="galU"
                     /locus_tag="VYN12_000478"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1414917.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(35221..36237)
                     /locus_tag="VYN12_000479"
     CDS             complement(35221..36237)
                     /locus_tag="VYN12_000479"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1414918.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            36449..36830
                     /locus_tag="VYN12_000480"
                     /pseudo
     CDS             36449..36830
                     /locus_tag="VYN12_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(37004..37429)
                     /locus_tag="VYN12_000481"
     CDS             complement(37004..37429)
                     /locus_tag="VYN12_000481"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1414919.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(37497..38147)
                     /gene="phoU"
                     /locus_tag="VYN12_000482"
     CDS             complement(37497..38147)
                     /gene="phoU"
                     /locus_tag="VYN12_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1414920.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(38162..38914)
                     /gene="pstB"
                     /locus_tag="VYN12_000483"
     CDS             complement(38162..38914)
                     /gene="pstB"
                     /locus_tag="VYN12_000483"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1414921.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(38916..39731)
                     /gene="pstA"
                     /locus_tag="VYN12_000484"
     CDS             complement(38916..39731)
                     /gene="pstA"
                     /locus_tag="VYN12_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1414922.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(39724..40587)
                     /gene="pstC"
                     /locus_tag="VYN12_000485"
     CDS             complement(39724..40587)
                     /gene="pstC"
                     /locus_tag="VYN12_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1414923.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(40705..41580)
                     /locus_tag="VYN12_000486"
     CDS             complement(40705..41580)
                     /locus_tag="VYN12_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1414924.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(41747..43078)
                     /locus_tag="VYN12_000487"
     CDS             complement(41747..43078)
                     /locus_tag="VYN12_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1414925.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(43079..43786)
                     /locus_tag="VYN12_000488"
     CDS             complement(43079..43786)
                     /locus_tag="VYN12_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1414926.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(43870..44172)
                     /locus_tag="VYN12_000489"
     CDS             complement(43870..44172)
                     /locus_tag="VYN12_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1414927.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(44159..44380)
                     /locus_tag="VYN12_000490"
     CDS             complement(44159..44380)
                     /locus_tag="VYN12_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1414928.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            44342..44901
                     /locus_tag="VYN12_000491"
                     /pseudo
     CDS             44342..44901
                     /locus_tag="VYN12_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45216..46907)
                     /locus_tag="VYN12_000492"
     CDS             complement(45216..46907)
                     /locus_tag="VYN12_000492"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1414929.1"
                     /translation="MNTKELIASKLSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTIAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            47043..47489
                     /gene="argR"
                     /locus_tag="VYN12_000493"
     CDS             47043..47489
                     /gene="argR"
                     /locus_tag="VYN12_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1414930.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            47540..50074
                     /gene="mutS"
                     /locus_tag="VYN12_000494"
     CDS             47540..50074
                     /gene="mutS"
                     /locus_tag="VYN12_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1414931.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            50221..51915
                     /gene="patA"
                     /locus_tag="VYN12_000495"
     CDS             50221..51915
                     /gene="patA"
                     /locus_tag="VYN12_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1414932.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(52245..52508)
                     /locus_tag="VYN12_000496"
                     /pseudo
     CDS             complement(52245..52508)
                     /locus_tag="VYN12_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            52706..54472
                     /gene="patB"
                     /locus_tag="VYN12_000497"
     CDS             52706..54472
                     /gene="patB"
                     /locus_tag="VYN12_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1414933.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            54611..55300
                     /locus_tag="VYN12_000498"
     CDS             54611..55300
                     /locus_tag="VYN12_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1414934.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            55304..55483
                     /locus_tag="VYN12_000499"
     CDS             55304..55483
                     /locus_tag="VYN12_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414935.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            55470..56819
                     /locus_tag="VYN12_000500"
     CDS             55470..56819
                     /locus_tag="VYN12_000500"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1414936.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            56943..58403
                     /locus_tag="VYN12_000501"
     CDS             56943..58403
                     /locus_tag="VYN12_000501"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1414937.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            58417..58848
                     /locus_tag="VYN12_000502"
     CDS             58417..58848
                     /locus_tag="VYN12_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1414938.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
     gene            58972..59043
                     /locus_tag="VYN12_000503"
     tRNA            58972..59043
                     /locus_tag="VYN12_000503"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59005..59007,aa:Glu,seq:ttc)
BASE COUNT        17276 a        11209 c        12838 g        17767 t
ORIGIN      
        1 tatccataac ttcaaaacag tgttttgagc aacctgcggc tagttttcta gtttgccctt
       61 tgattttcat tgagtatcaa aaagcaagcc atttttggct tgcttttttc atctttaaaa
      121 atgattggcc tgcttaacga ggtggtagtc caagggcaat acggccatag cgactgattc
      181 gtgtgatttt ccaagcaggc gaccaggtaa cttcaacctt gatatctttg ataccctcga
      241 tttgtttcag acctgccacg atttcaatag gcaggctttc ggcgcaatca caggcagtat
      301 cggtgaaggt catgacaatc ttgcagagcc ccgtttcatc cagattgatt tcataaatca
      361 gacctagatt gtaaacatcc aattccacat ctgtatcaaa aactttctct agtttttcga
      421 tgatttggtc ttgcaaggcc aaagcacggt cattgatttt gatatcgtct ctcatagcag
      481 tccctccacg tgataaatat cctctatttt ctcataattc tgacaatttg gcaagttttt
      541 gatgaatttt ctgaaaaata tgataaaatg aagaaaatac ggaatcaagg ggaagtctat
      601 ggagcagatt ggaaaagtct ttagacaatt acgagagtca agaaatatct cactgagaca
      661 agcaaccgga ggacaatttt cgccgtctat gttgtcccgt tttgaaacag gtcagagtga
      721 gctttcggtg gaaaagtttc tatttgctct ggaaaatata tctgccagtg tggaggagat
      781 cctctttctg gcgagaggtt tccagtatga tacagattct gagttgagaa aagaaattac
      841 agatgtcttg gaaccaaaga atatagcacc tcttgaggac ttatatcgca gggagtatca
      901 aaagcatgcc cattctcaca acaaacagaa acatattcta aatgccatta ttatcaagtc
      961 ttatatgaag agcatagatg aaagggtaga cttaacagca gaggaaggaa aagtccttca
     1021 tgattatttg ttttctaccg agatctgggg aatctatgaa ctcaatttat tttcagtcag
     1081 ttctccattt ttatctgttt ctctttttac tagatatgta cgagaaatgg tacgtaaatc
     1141 tgattttcta atggaaatgt ctggcaatcg aaaccttttt catactatac tattgaatgg
     1201 ctttttagct agtattgagt gtgaagaatt taccaatgcc tattatttta aacgtgttat
     1261 cgaagagcat ttctacaagg aaaatgagac ctatttccga attgtttatc tgtgggcaga
     1321 aggtctcctt gatagcaagc aaggtagagt caaggaaggc cagaaaaaga tggaggatgc
     1381 tgtccgtatt tttgagatgc ttggctgtaa taaatctgcc gaatactata gaaaaactcc
     1441 cgattcttga atatctgcaa accaagaaaa aatttgaagc gatagaactg ttgccctctc
     1501 tcaggtcatt acaaaagttc tatcgttttt ttgctcattt tgtttgttgc atatattcaa
     1561 aagaatcgtt tcgcaaattc ataagtgcta tactaaagct attcttgatg tagaacttag
     1621 aacaaggagg gagattatct atgaaactat tgtttagaaa tccagcttat agaattttga
     1681 ctttatcacg cttcttcaat gcttttggtg cttcgatttt caacctggtc tttatcgtct
     1741 atgcatcgac cttgtcacaa gcatcttttg ctgttgctat ggcgaatatt gtcatgattc
     1801 ttccgaccct ctttacagtt tttgtaggga ttcgggcaga ttacacgagg gacaaggtca
     1861 aatggatggt ctatagcggt ttgtttcagg cggttctatt ttttctagca gccctagttg
     1921 ttcagcaagc tagtctcttt gccttttcta gcctgtgttt gatcaatgtc attagtgata
     1981 tcatcagtga ttttgcaggt ggcctgcgta tgcctcttat taaggaaaaa gtagctgaag
     2041 atgatctgat ggaggcttat tctttttcac agttcatcac ctatatttca gctattggtg
     2101 gtcaagcttt cggagtctgg ctcttagctc tatcggtcaa caatttttcc ctcgttgcgg
     2161 gaattaatgc ttgctttttc ctcgtatcag cctttattct ttttttagga aaaagcaaat
     2221 tgagcctgtc aatttcatct gctgatggtg aaaaactaaa aaatgagaag ctttctatca
     2281 aagaccagtt cctaacaatt taccgaaatt tacgtctcgt ttttcttaaa agtggacaga
     2341 aaaactttgg ttttatgctc tttgctgtct tgcttattaa ttccttgggt ggcgctttgg
     2401 gtggaattta taatatcttc tttttgagcc attctctctt gaatttttct tatacagagg
     2461 cactatttat caatcaagtc tgtgttttgt tagcaatcat cattagtagc cttacgggca
     2521 atgattattt tgggaagcag tccttgccta gattgatgat gtgggagacc gtaggactta
     2581 gtctagttgg tttggctaat ttattcaatc aagtcgtgct tggtttgcta tttctcttct
     2641 ttactctgta tgtgtctggt aaagttcaac caaagattag tgccatgctc atgaaaaatc
     2701 tagctccaga ggttctagct cgtactagta attttttagg tctattgttt accttatcca
     2761 tacctgtggg aacagcttgt ttttcactag tagccgtatg gaatatacag ttgacttgga
     2821 tgctatttgt tggtttttcc ttgctagcta tttttttgac aattcttaat ctcaaaaatg
     2881 atatctaaat cctaattttt ttcttactgt tttaatccct ttatttatgg taaaataaga
     2941 ctattaagtt taaagaggat tccctatgaa attacaaaaa ccaaaaggaa cgcaggatat
     3001 tttacctgct gaatctgcca agtggcagta cgttgagggc tttgcccgtg agattttcaa
     3061 gcgctataac tatgcagaag tgcgcacgcc tatttttgag cattacgagg ttatcagtcg
     3121 ctctgtcgga gatacaacgg atatcgtaac caaggaaatg tacgattttt atgacaaggg
     3181 tgaccgccat attaccctcc gtccagaagg aactgcgccc gttgtccgtg cctatgtgga
     3241 aaataaactc ttcgccccag aagtgcaaaa gccaagcaag ttctactata tgggacctat
     3301 gttccgttat gagcgtccac aggcagggcg cttgcgccaa ttccaccaga ttggtgttga
     3361 gtgttttggc tctagcaatc cagctaccga tgtggaaaca atcgttatgg cagcccattt
     3421 tttgaaggaa atcggtattc aaggtgtcaa attgcacctc aacactcttg gaaatcctga
     3481 gagccgtgca gcctaccgcc aagccttgat tgactatttg acaccgctca aggagacctt
     3541 gtctaaggat agccaacgtc gcttggagga aaatcctctt cgtgtcttgg actctaagga
     3601 aaaagaagac aaggtggcag tagagaatgc gccgtctatc ttggactttc ttgatgaaga
     3661 aagccaagct cattttgatg ctgtgcgtca gatgttggaa aatcttggag tagattacat
     3721 catcgatacc aatatggtgc gtggtctgga ctactacaac cacaccattt tcgagtttat
     3781 cacagagatt gagggcaatg acttgacagt ctgtgcgggt ggtcgctacg atggtttggt
     3841 tgcttacttt ggaggccctg aaactgctgg atttggtttt gggcttggtg tagagcgcct
     3901 gcttctcatc cttgaaaaac aaggcgtggc cctccctatc gaaaatgccc tagatgtcta
     3961 tatcgcagtc ttgggtgatg gagcaaatgt caaagcccta gaactagtcc aagctcttcg
     4021 ccaacaaggt ttcaaagcag agcgtgatta cctcaaccgt aagctcaaag ctcagttcaa
     4081 gtcagccgat gtctttgcgg ctaagaccct catcacccta ggagagagcg aagtcgaaag
     4141 cagacaagtg acagtcaaga acaaccaaac ccgagaagaa gtgcaagtgt cacttgagac
     4201 aatcagccaa aacttctcag aaatctttga aaaattagga ttttatactc aatgaaaatc
     4261 aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtagat
     4321 gaaactgacg aagtcagtaa ccatacctac ggcaaggtga agctgacgtg gtttgaagag
     4381 attttagaag agtattaatg atagataaag tggtcaggaa cttactcctg acctttttcc
     4441 tttgcaaaat gacaaaaatc ataaactttt tgacaactat acttgtcaaa aagaaaaaga
     4501 tgtgttacaa tgtaagcaag ttaagagaaa agaagaaagg aaacgcagaa atgtcgagat
     4561 tattacaaga aatgattgga aaggaaccaa ttataacggg agtgtatatt gggccagata
     4621 actgggaagt tgtggatgtt gacgaggaat gggtcaaact acgtagtgtt gataaaaagg
     4681 ggaaagaaaa attcaagttg caacgtattg aagatatcca aaccgttgaa tttgacggag
     4741 agtaggtgtg taacatgcaa ctaaaaaatc gtctaaaaga gcttcgagct cgcgatggtc
     4801 tcaatcaaac cgacctagcc aaactggcag gggtttccag acagaccatt agcctactag
     4861 aacgggatga gtacacccca tccattatca ttgccctgaa aatatctcaa attttcaacg
     4921 aaacagtcga atcggtattt cgtttggagg aggacgagtg atgaacaagt ataaagtgat
     4981 ttattatgta gtggtcatag ctttattagt cagcgtattt ctactgattg ggatggacct
     5041 aagctggttt aatccctatc aaagcgacca atttgtttgg gtctactttg ctctcatccc
     5101 agtaactgaa tggattgaaa agaaatccaa aaatctagca agtgaaaaag gagaatgaat
     5161 atgaaaaaga aacgtagatt gttatttttg atgtctattg tcttgggggg gttcttgggc
     5221 atgtttgtag ggatgtttaa ggcacgtgtc gaatcccacg aaattatttt agatgtaaaa
     5281 gccttgatgc catggatatc agctatttgt ttactgatag gtttcattag tatgtttttg
     5341 actttcaatt tcttaaagaa aagcagaaaa tttcattcct tgtatcaaga ggaaatggat
     5401 gacgatctga atgaaaccta ttatgtgcaa atgtatcgga atcttgagtt tggaaccatt
     5461 gcttttaata ttacaggtgt agcgattcca ttggctattt ttatttcatt aagtgaggtg
     5521 attatattgc atacaaaccc tcaaacattt ttcctttctt tcttactctt tgtggtattc
     5581 ttagtcgctc aaaaatctct ttttaaaacc attgcgattg ttcgtcagtt tgatttggaa
     5641 tttttcgcta caccaaagga tgtcttgaac tatataaatt cttatgatga aggggagcgt
     5701 caggctaatt tggaacagag ttttcgaatt ttattccaat tacaccaata tgtcttacca
     5761 gccttatata tttttcttat tatcatttct ttcttgacag gagagattca gttactagct
     5821 ttcttgcttg taggagccat ccatgtttat atcaatgtga tgcagttacc tatggtaaaa
     5881 cgttatttca aataaaggag ttatctatga aattacttaa aaaccttggc tggattcttc
     5941 tagcccttct atccttttta tttatctatg gctttattca ggggctcgcg actgcgtcgc
     6001 ttgctttagg cgcttcaccc tatgctgtta ctctactcta tgtggccttg gctggagtat
     6061 atgtgtacgg catttacaaa tggtatcaga aggctcctgt ttatattgag aagagcggct
     6121 ttaaccgatt tatttggctt cctgccttgg tttggttctt atctctggtc gttcaattct
     6181 tcttgccaga tgatccttca gtaaatcaac aaatagcgac agacttgacc ttgtctcaac
     6241 cacttttctc attctttgct gtggttattt ttgctccttt gacggaagag attgttttta
     6301 gagggatgtt agcacgctat ctctttccta agcaggacaa tagtaaacga accctgattt
     6361 ttcttctggt atctagtctt ctatttgcct tgattcattt tccaggtgat gtgcaacaat
     6421 tttttgtcta ttttagcctt ggttttagtt tgggtttggc ttacattagc agaaaaggtc
     6481 tggtctacag tatttctctt cacgctttga ataatttagt cggctttttg atgattctca
     6541 tgctataata gagtcaggag gtcacatgaa acgagtaatt ttagtagcag tgattcaggc
     6601 agtcattcta tttttcatca ttggagcgct agcttatgcc ttcaaaggcg atttcttcta
     6661 taactatcta gcagttgtct ttgctcctat tgcaggtgta ctgcgttttg ggacggctta
     6721 cataacggaa attgtcttgc ctcgaaaggc agccgaaatc gctgaaaagc gtaaagcagg
     6781 caaaaattca aaataaaaga gtccggtgaa gttcatcgga tttttgtatt atactcaatg
     6841 aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaaacactg ttttgaggtt
     6901 gtggatgaaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac
     6961 gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat
     7021 acctacggta aggcgacgct gacgtggttt gaagagattt tcgaagagta ttagcgctaa
     7081 tttttagggc tttcatctga cttttaaaga ctggcaaact tttctgatga ttttcatgaa
     7141 gagcctgcgc ttttatggta aaatagtaac agaataaaag aggagagaaa taatgaaacg
     7201 tagtatgtat gctggtcgtg ttcgtgagga acacatcgga caagaaatag ccttgaaagg
     7261 atgggttggc cgtcgtcgtg accttggtgg tttgatcttt atcgatcttc gtgaccgtga
     7321 aggaatcatg cagttggtta tcaaccctga aaaagtatct gcagaggtta tggcaacagc
     7381 tgaaagcctt cgtagcgaat ttgttattga ggtgactggt caggtcgctg cgcgtgagca
     7441 agccaatgat aagttgccaa ctggtgcggt tgagttaaac gtgacagctc ttattgtgct
     7501 taacacagct aagacaacac catttgagat taaggatggc attgaggcaa atgacgatac
     7561 acgtttgcgt taccgttacc ttgaccttcg tcgtccagaa atgttggaaa atcttaaact
     7621 tcgtgccaag gtgacccact ctatccgcaa ctatttggat gagttggagt ttatcgacgt
     7681 ggagacacca ttcctttcta agtcaacgcc tgaaggggcg cgtgattatt tagtgccgtc
     7741 tcgtgttaat aaggggcatt tttacgctct tcctcaaagt ccacaaatca cgaaacagct
     7801 cttgatgaat gctggttttg accgttacta ccaaatcgtt aaatgtttcc gtgacgagga
     7861 cttgcgtgga gaccgccagc ctgaatttac tcaggtcgac ttggaaacgt ccttccttac
     7921 tgagaaagaa atccaagata ttacagaagg cttgatcgcg cgcgtgatga aggaaacaaa
     7981 aggcatcgaa gtaacgctac cgttccctcg tatgaaatac gatgatgcta tggctcttta
     8041 cggttctgac aagccagata ctcgttttga catgttgctt caggacttga cagaagtggt
     8101 caaaggtgta gactttaaag tcttttcaga agcacctgct gtaaaagcga ttgtggtcaa
     8161 aggagctgcg gacaactatt cacgtaaaga catcgacaag atgacggaag tagccaaaca
     8221 gtatggtgcc aaaggtcttg cttgggtcaa ggtggttgat ggagaattaa acggaccagt
     8281 tgccaagttc ttgactggta tccaagaaga attgacaaca gcgcttgttc ttgaagataa
     8341 ggacttggtt ctctttgtgg cggatacgct tgaagtggct aatgcaacac tgggtgccct
     8401 tcgtggacgt attgctaaag agcttggctt gattgataat gataagttca acttcctttg
     8461 ggtggttgac tggccgatgt ttgaatggtc tgaagaagaa ggccgctaca tgagcgccca
     8521 ccatcctttc acacttccac aggaagagac tgctcacgaa ttagaaggtg atttggctaa
     8581 ggttcgtgcc attgcttacg atatcgtctt gaacggttat gagcttggtg gtggtagcct
     8641 tcgtatcaac caaaaagacc ttcaagaacg catgttcaag gctcttggtt tctcaactga
     8701 agaagccaat gaccagtttg gtttccttct tgaagccatg gactatggtt tcccaccaca
     8761 cggtggtttg gctatcgggc ttgaccgttt tgtcatgttg cttgctggag aagaaaatat
     8821 ccgtgaagtc attgcctttc ctaagaacaa caaggcaact gacccaatga cacaagctcc
     8881 atcaacagtc gctctcaaac aactagagga actcagctta caagtagaag aagatgaaac
     8941 aaacaaaacg aattaagcgg tggcgctatt atctgcgccg ctttgcttat cagataaaaa
     9001 ttttacgtgt cttacaaagt atctctcgag aaaagtatga tgagaagatt tcggcctctc
     9061 tggtctatgg ttttttatca gcagtagcag ttaatttctt tttccaacca gggcatgtgt
     9121 attcgagtgg tgcaacaggt ctggcacaga ttatctctgc cttgagtaat cactggtttg
     9181 gttttcatat tccgatttcg ctaagctttt acgccattaa cttccctttg atggtcttag
     9241 cttggtatca gattggccat aagttcaccg tctttacctt tatcacggta tctatgagtt
     9301 ccttctttat ccagtttgtc cctgtggcaa ccttgacaga ggatcccatt atcaatgccc
     9361 tttttggggg tgttgttatg ggtttgggga ttggttttgc tcttcgaaac aatatctcca
     9421 gtggtgggac ggacatcgtc agcctgacta ttcgtaagaa aacgggtaag aatgtcggta
     9481 gtatttcttt cttggtaaat ggaactatca tgctgatagc aggtttgacc tttggttgga
     9541 aatacgctct ttattctatg attaccatct ttgtctctag ccgtgtgaca gacgcagtct
     9601 ttactaagca aaagcgtatg caggccatga ttgtgacaaa tcatccagag aaggtaattg
     9661 aaaaaatcca taaaaaattg caccgcggag caaccatgat ccacgatgca gaaggaacct
     9721 ataatcacga gagaaaggca gttttaatca ctgtcattac acgtgcagag tttaatgaat
     9781 ttaaacagat tatgacacaa gtggatccaa gctcctttgt ctctgtctcg gaaaatgttc
     9841 atattctagg aagatttgtt gagatagata attagtgatt aatactcttc gaaaatctct
     9901 tcaaaccacg tcagcgtcgc cttgccgtat atatgttact gacttcgtca attctatctg
     9961 caacctcaaa accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaaccat
    10021 gttttgagct gacttcgtca gtttcatcta caacctcaaa accatgtttt gagctgactt
    10081 cgtcagttct atctgcaacc tcaaaaccat gttttgagca acctgcggct agcttcctag
    10141 tttgcacttt gattttcatt gagtataaaa agatcttggg aaaagactca atttcagtag
    10201 aaaaggaagt aaatcttccc acattaaaac gcatagtatc aagttttttc aatacctgat
    10261 actatgcgtt tttgctttta acgacttttt gcccagtctc ttatttttcg ataattttgt
    10321 gggcgatcaa ttgacggtaa caaatttgtt tattgttttt attatcatta ataatctgga
    10381 gaatagtttc aagggaaaca cgaccaagct ctaaactatt gatatcgaca taggctgcca
    10441 agttgagctt gggattaacc gagtcaaagc tgagaacagg gacatccagc tggtgtttgg
    10501 caatatagtt acaaacacct tcagctagga ggctatcggt tgtgatgata gcatcaattt
    10561 gtggatcgtg cttgaataat cgcttgctaa atttatagcc cttttcttcc agaaactcgt
    10621 cggcaaagta gatgcgattg ttgtcagtgg taagtttgta atgtttaagc gcctgttcat
    10681 agcctgttaa acggtctttg gtcacgaaga gctttttact tcctccgata aaggcaatgc
    10741 gtttgcagcc ttttttgatg aaatattcag tcgcatcaaa accagcttga acattgtcgt
    10801 tgtcgacaag tgggatgaaa ggagatagag atttacctaa gataaggaag gggaactgtt
    10861 cttctgcgac gagttttacg agagggtctt cttcttgggc atagagaaag attagcccat
    10921 ctacacgctt gccgtagacc atttgtgaaa tagcgttgag acgctccttc tcatctttcc
    10981 ctgttgctat ctgaatggca tagtggtttt cagatgcgac ttgagagatg ccacgtagaa
    11041 ccgatggaaa gaaaggattc tggtagaagg cgtctgagtc atcaggaaga actaatccga
    11101 taacctgagt atagctgctt accaagctac gagcgttgag gtttgggtgg tagttgagtt
    11161 ccttcatagc tttgcgaacg cgtttttttg tttcgtcgct aatggttgat ttattttgaa
    11221 taacacgggt tacggttgaa ggcgaaacac cagcagcctt ggccacgtct ttaatcgtaa
    11281 cgggcataaa aatctcctat ttatggtaat ttggatcacg gaaatgtgtt ttataaaaga
    11341 tagtgaccag atacagaaca aaaagaatat tttgtacagt aatcagggtt gtcatatttt
    11401 ggccaaataa tcccaaaata agtgtaatca gagtcggcaa tcctaaacag ttcaagataa
    11461 agtgatagca ctctttaaag gttctaaatg aaaagaggcg tgatttctta gtgatataaa
    11521 ggagaagact agctcctaga gagacgataa agaaattcaa accaaagagg aagctcgcac
    11581 cgagaactag gaagaggctg atatagacac gattttgttg gtaccagtct ttagaaattg
    11641 cttgggtcaa gctgtctttg cttttgaaac tctcagtctg aatggctcgg taagagatgc
    11701 gggtcagttc cttgctttcc ttgctgatga ctagctcatt tgtatcgaaa tgcagttgca
    11761 agtccttagg taattccttg atttgacttg gaccaatcac aacagaaggg gcttgactag
    11821 ctgttccagt ataagttaat gtgccatcga caattgtagc atgttcagag agatcctgga
    11881 caacctcatt tgtcagaggt tcatagacat tatcgataaa agtttctagc ggataggtct
    11941 cctgggagct gttttggata gcaatgggta ccatagacaa gctgataagg aagatactgg
    12001 taaagagaag ttgaaaccag ttgagctcga aacgtttgga caggggctta cgaaaccccc
    12061 aaatacttga aaaataggaa aatggatatg gaagcatagg tatctttcta aaaggtgttt
    12121 tctatatgag tattattata tagagaaatg cgctttattt caagtctagg agaaaaattg
    12181 cttgctacaa ggatattatt tacagtgaca attgctaata atcaatgaaa atcaaagtgc
    12241 aaactagcca caggttgctc aaagcacaac tttgaggttg gagataaagc tgacgtggtt
    12301 tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc ggggataaat tatcccttgt
    12361 cgccaccact tgtaagtcct gaaacaaagt tcttttgtag gaagaagaag agaatacaga
    12421 ttggaagggc gatgaggata gcacctgctg agaagtaggc aatcttcaag tttttcgcat
    12481 tgttaacgaa ggtttggaga cctacggcaa cagtaaagta ttctttctca cgaagcaaga
    12541 aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa
    12601 ccattgggcg aacaagtggt agaacaattt gccagaagcg gcggaagtgt cctgcaccgt
    12661 ctagttttgc agattcgtct aaagacattg gcactgtatc gaagtagcct ttcatgagcc
    12721 aagcattcat cgggatacca ccaccaacgt agaggaagat gaggaaccag ttgtggttaa
    12781 gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa agcggccata gttggcacca
    12841 tttggatgat caagaagaag accaaacttt gtttacgagc caagaagttg taacggctgt
    12901 aagcataacc agcaagtacg atgatacttg tttgaacagc catggtaatt aaggcgataa
    12961 tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt gaagaggcct ttaaagttat
    13021 caaaattgag gtcgatatta gtatctagtt taaaggctga gacgttacct gctttaaagg
    13081 ctgacataat ggtaatcaac agtggataga taattacaat tgatagacca atcaggtaaa
    13141 ggtaagtaag gctttgagtc agtctacgtt tgagtttaat tgagttattc atcttagacg
    13201 tcctccatat caaatgcgtg tagtttcttg aatgcgatca tagagattga gatgacaatg
    13261 atagagataa tcaaggtaac agctgccgcc attgagtatt gaggagatgt acctgttgtc
    13321 aaacggtaga tccatgagat caagatatcg gttgaaccag ctccacctcc gacactacca
    13381 ggtcctccac cattgaagag gtacatgata gagaagttgt taaagttgaa ggtgtattgg
    13441 ctaatcaaag taggtgccgc aacagccaaa atcattggga aagtgatgtt gcggaatttt
    13501 tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa ggtcgttagg aatagattgc
    13561 aagataccca aagtcaaaac gtagatgtat gggaatccga gccaaccttg catcataatc
    13621 aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa
    13681 ggaaggaatt tagccaagat tggcaatact tgagtgttga tagcaccgac actatcgtta
    13741 aacatatttg agaatgtcaa gatagtgatg aaggctggga cagcccaagg aagaaggaaa
    13801 ataacaccaa agatacgttt tcctttgata aatggttggt tggcaatgat agctgtgaag
    13861 ataccaatta cgatttgtaa agtagaagct gccaaagccc aaatgatagt ccaagaaaga
    13921 acagaaccaa aggcagaacg gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa
    13981 ccaacccagt ccaacaactt gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg
    14041 atcatcaagg ttacgataac tgggaagata atcgcgaagg tcatggcaac ataagatgga
    14101 atgatcaaga ggtaagggaa gccattttca taaatccctt tgatcatgtc tttgagtgtg
    14161 cgtggaactg gaattccatt gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt
    14221 gagaaataaa agagtacata aacgattaca aagattagat ggaaggcacc acgaatcagc
    14281 ataaagaggg aattatcacg acctggtttg tcaccaagag tgatgaggtt gctcaattca
    14341 ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg ttacaccaag gaagataaaa
    14401 cctttggctt tttgtttatt gtaaatctgt cctaacccag gaatgataga cagcagggct
    14461 gctttactag gttgttgctt ttccatatta actcctttca taggatacta cttttttata
    14521 agaaagctaa attatttgtg tctctattga taaattcaaa gggggatttg atttccaccc
    14581 cccttgaaca aattttttat tcaccaaatt tttgtttgat tgtttctttg atcaatgtta
    14641 cagcatcgtt agcagctgtt ttagcatctt tttgaccact tacagcatca aagagcatat
    14701 ttttcgctgg atcccaaact gcagacattt gagagatgtt tggcagtggt tgagtgttct
    14761 tgaactgttt gataacagct gttgtcaact catcgttttt accttcagcg tatgaacgag
    14821 cctcagtatt agctgggatt tcgttagtct tatcatataa tactttttgt tgttcagttg
    14881 caacaaggaa gtctacaaat ttttgagaag cttcaaggtt cttaacggct tgaggaatga
    14941 cccaagcttt accaccaccg aatgcagcat attcttttcc atttggaaga gttgggatag
    15001 ttgcaactcc gtagtttact ttagcatctt taaaggcttg agctttccaa ggtccgtcga
    15061 tgatagcagc tgttttacct tcttggaatt gagtttggat taagtttcca gcaccttctg
    15121 tatcttgcat acctttaggc catttttcgt accaagattt agcgtagttg atacctgcga
    15181 tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt
    15241 aagcaccgtt accggcaaga agtccatatg tatagtagaa gtttgtccag tcagctagga
    15301 aggcagtagt tttaccatct tcaccagcga atgcgtattt gctatcttta gcaaggtttt
    15361 ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc tttgttgtag tacataacaa
    15421 gtgactcgat aacggcagga gcaccgtaaa ctttaccatt agcagctgtt acaagagatt
    15481 tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag
    15541 aaccaaggct acctacacgg tcgtatggag ccatcataac atcagggaca ttaccagatt
    15601 ggttgtcaag agaaagttta tcaagacctc ctagagcatc accagtttta agagtgactt
    15661 ttactccagc ttctttttca taagctttag caacctcttc aatatagctc ttatatccct
    15721 cgtctacata tacagtgagt tctttgactt cagatgaacc agaatcagca ggcttatcag
    15781 cagttttgct tccgcaagct accaaaagca agctagcaag tgtaacagtt ccaagcaccg
    15841 cagtgctctt cataaattta gatgacatag tgtattcctc ccaaagaata gcaagtttta
    15901 ttgataagga aacgcaaacg ttttccttta tgagcttagt atagcacaaa tagaaaacgg
    15961 ttgcaagtat tttttgtaaa aattttaaaa aatttttaag cttgatttga tagcataatt
    16021 ttgcatttta atagaagaaa agtatgaaat agataagaat acagtatttt taataaaaat
    16081 atatggaatc tgtctaaaga gggaaatcag gaggggctac ctccctgttt ctaatcccta
    16141 tctattttct atagacgttt gtgctttgtt gcatataaat tcaagctccc taaggaggtt
    16201 ttgtactttg tagactgtct cgtgagagtc aaactttagg attagatagt tttaagttat
    16261 ctttgctaaa atgagttagt ctccttaaaa ataatcaaaa aagtttttta aaaacgcttg
    16321 caattatgct tgaaaaggag tatacttata agtaacgcaa acgtttgcgt ctgcaaaata
    16381 cgcaacgttc cattatttta acacacgagg tgctattatg aaaaaacgtc aaagtggtgt
    16441 gttgatgcac atctcttctc ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc
    16501 ttacgacttc gttgatttct tggtccgtac aaaacaacgt tactggcaaa tccttccatt
    16561 aggagcaact agttacgggg attctcctta ccaatctttc tcagccttcg caggaaacac
    16621 tcattttatc gatttagata tcttggtgga gcaaggtttg ttgggagcga gtgaccttga
    16681 aggagttgac tttggtagcg atgcgtctga agttgactat gctaaaatct actatgcacg
    16741 tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa gtcggagatg ttaaagattt
    16801 tgagaaattt gctcaagaca accaatcatg gcttgagctc tttgctgagt atatggctat
    16861 caaagagcat tttgacaatc ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg
    16921 taaagcttca gcacttgaaa gctatcgtga gcaattggca gacaagttgg tttaccaccg
    16981 tgtgactcaa tacttcttct tccaacaatg gttgaaattg aaagcttacg ctaacgacaa
    17041 ccacattgaa atcgttgggg acatgccaat ctacgtagcg gaagattcaa gtgatatgtg
    17101 ggcaaatcca catctcttca aaacagatgt caatggtaag gctacttgta tcgcaggatg
    17161 cccaccagat gagttttctg taactggtca gctttggggt aacccaatct atgactggga
    17221 agcaatggac aaagacggct acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat
    17281 ctacgatatc gttcgtatcg accacttccg tggcttcgaa tcttattggg aaatccctgc
    17341 tggttccgat acagcagcac ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc
    17401 agccgttaag gaagaacttg gtgagctaaa catcatcgca gaagaccttg gcttcatgac
    17461 agatgaagtg atcgaattac gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt
    17521 tgccttcaac ccagaagacg aaagcattga tagcccacac ttggcacctg ctaactcagt
    17581 tatgtacaca ggaacacacg ataacaatac ggttcttggt tggtaccgta atgagattga
    17641 tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt aaagaatacg aaacagtggt
    17701 acacgctatg cttcgtacag tattttcatc agttagcttt atggcaattg caactatgca
    17761 agatttacta gaattggatg aggcagctcg tatgaacttc ccatctaccc ttggtggaaa
    17821 ctggtcttgg cgtatgactg aagatcaatt gacaccagct gtcgaggaag gtttgcttga
    17881 cttgacaaca atttatcgcc gaattaatga aaatttggta gatttaaaga aataagacaa
    17941 taatcaggag acaactaaac atgttatcac tacaagaatt tgtacaaaat cgttacaata
    18001 aaaccattgc agaatgtagc aatgaagagc tttaccttgc tcttcttaac tacagcaagc
    18061 ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa agtttactac atctcagctg
    18121 agttcttgat tggtaaactc ttgtcaaaca acttgattaa ccttggtctt tacgacgatg
    18181 ttaaaaaaga acttgcagct gcaggtaaag acttgatcga agttgaagaa gttgaattgg
    18241 aaccatctct tggtaatggt ggtttgggac gtttggctgc ctgctttatc gactcaattg
    18301 ctactcttgg tttgaatggt gacggtgttg gtcttaacta ccactttggt cttttccaac
    18361 aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc atggttgaca gagcaaaact
    18421 ggttggttcg ctcaagccgt agctaccaag taccatttgc agactttact ttgacatcaa
    18481 ctctttacga tattgatgtt actggttatg aaacagcgac taaaaaccgc ttgcgtttgt
    18541 ttgacttgga ttcagttgat tcttctatta ttaaagatgg tatcaacttt gacaagacag
    18601 atatcgctcg caacttgact ctcttccttt acccagatga tagtgaccgt caaggtgaat
    18661 tgctccgtat cttccaacaa tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg
    18721 aagcaatcga aaaaggaagc aacttgcatg accttgctga ctacgcagtt gtccaaatca
    18781 acgatactca cccatcaatg gtgattcctg aattgattcg tcttttaact gcacgtggta
    18841 tcgagcttga cgaagcaatc tcaattgttc gtagcatgac tgcctacact aaccacacaa
    18901 tccttgctga agcgcttgaa aaatggcctc ttgaattctt gcaagaagtg gttcctcact
    18961 tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg
    19021 ttcaaatcat cgatgagagc ggacgtgttc acatggctca catggatatc cactacggat
    19081 acagtgttaa cggggttgca gcactccata ctgaaatctt gaaaaattct gagttgaaag
    19141 ccttctacga cctttaccca gaaaagttca acaacaaaac aaacggtatc actttccgtc
    19201 gttggcttat gcatgctaac ccaagattgt ctcactactt agatgagatt cttggagatg
    19261 gttggcacca tgaagcagat gagcttgaaa aacttttgtc ttatgaagac aaagcagctg
    19321 tcaaagaaaa attggaaagc atcaaggctc acaacaaacg taaattggct cgtcacttga
    19381 aagaacacca aggtgtggaa atcaattcaa attctatctt tgatatccaa atcaaacgtc
    19441 ttcacgagta caaacgccaa caaatgaacg ctttgtacgt gatccacaaa taccttgaca
    19501 tcaaagctgg taacatccct gctcgtccaa tcacaatctt ctttggtggt aaagcagctc
    19561 cagcctacac aatcgctcaa gacattatcc atttaatcct ttgcatgtca gaagttattg
    19621 ctaacgatcc agcagtagct ccacacttgc aagtagttat ggttgaaaac tacaacgtta
    19681 ctgcagcaag tttccttatc ccagcatgtg atatctcaga acaaatttca cttgcttcta
    19741 aagaagcttc aggtactggt aacatgaaat tcatgttgaa cggagctttg acacttggta
    19801 ctatggacgg tgctaacgtg gaaatcgctg agttggttgg agaagaaaac atctacatct
    19861 tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa agcagcttac aaatcaagcg
    19921 aattctacgc tcgtgaagct atcaaaccat tggttgactt catcgttagt gatgcagttc
    19981 ttgcagctgg aaacaaagag cgcttggaac gtctttacaa tgaattgatc aacaaagact
    20041 ggttcatgac tcttcttgac ttggaagact acatcaaagt caaagagcaa atgcttgctg
    20101 actacgaaga ccgtgacgca tggttggata aagtcatcgt taacatttct aaagcaggat
    20161 tcttctcatc tgaccgtaca atcgctcagt ataatgaaga catctggcac ttgaactaat
    20221 actcttcgaa aatctcttca aaccacgtca gctttatctg caacctcaaa gcggtgcttt
    20281 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taagatacaa
    20341 atttatacta atacattttg taaaaaagcg agtttcgatt gaaattcgct tttttaaatg
    20401 ctgtggattt gggtcaatct tgtctaaaaa tagggaaatc ctagatacag tgaaggcttt
    20461 aaatgctggt ttttactgtc ttcagcctta tattttttcg tagttggtta cctcacatct
    20521 cttgtattcg cttacataaa gtattataat ataattgtag gaaagaaggt gtttttatga
    20581 tatacacact taaattggtg ttgtttatta cctttcttgt aataagcttg ttacctgata
    20641 agatttttgg aaaaaataaa aaaatttgga aaatagtttt tgcaatattg acggcagtgg
    20701 cagcattgtc atttatgtac taagttattt taagaatgta gggaaataaa ccctacattc
    20761 tttttagttt tttctgtttt ctaaattcta tttatccaag cgattcaaca tttcttgctt
    20821 cttcgcttca agttctgcac gcttttcttc gatttcggca tgttttttct cgagttcaga
    20881 acaacttgca ccattgctaa attcttttcg ccatcaggag atagggtgag tcgacatgtc
    20941 tattactcac ccaaagcagt cctacaaagc aggaattttc tgttactttt ttggaaatag
    21001 taacgtttat acagctttga cacttcgtat caaagcgcca aacacactcc gagggattta
    21061 cagaaagcag aaaaggaatg atctggtata agatcattcc ttttctctct ttttctttaa
    21121 gtaattatat acaatgtacg acgaagtcgt cattgcaatg ctgatccacc acctaaaggg
    21181 aactttaaac aacattgata agataaagaa tataaacaac gaaaatacgt tatacccaat
    21241 taattttatt gtatatctca tgattaaaag ttaatccttc cgttgttagg aatggcatca
    21301 tttttatccc ataattgtgc taaataagtc cccggtgata ataaattcat agcgaattct
    21361 aaagcaacat catttacaaa ccaactacct agatatctag aaattgctga acgaatagca
    21421 ctttttgctg catgttttcc ttttacttta attagatttg caaggcctgc agtagttcct
    21481 cctaatgcta aagctattgc agtatctaat agagcaccca tttgattaac tgtaatacct
    21541 tgccaagctg ctctaaatgg agagtatgta ggtgggattg tataatcgcc ttgtaattgt
    21601 cggttaatta cttctttgat ccattgttgt gagacgtctg gatgaaaaga ttggatttcg
    21661 tttgcaagtg tattgatttg ttcttctgtt agagaagtga caggttgaag ttccatattt
    21721 gtttcaattt gtgatacttg ttcagaagcg tatacagctg aaacacttgg aatcgctgat
    21781 acaattaaca caattgacgt caaaaaaacc gaaataaatt tcattaattt gttcatgagc
    21841 ttttctcctt tttatttgta tctgcttaca ttttatcata tactgttatt atagtcaaaa
    21901 aaatatgcta ttatgttaaa aaaatatttt tcaaaatata aatggacgga tttattttgg
    21961 attttatttg ttattttgac ctgcctctat attggtaacc atgatttgtt tactctcaat
    22021 catcaagaat tctcttttcg tggtagcgtt tggggtctgg tactggcctt atatcactta
    22081 ttgttcattg ataagtttgt aatttcgaat cgaaaataaa gattagaact atgattgact
    22141 ggctactttt aatattgatt ttggaggaag attttgtctc tattatttat tattttaaat
    22201 ttatttattt tgtataagat ctattctttg aggcgggaaa aatcgaaata cttgatttat
    22261 acggcctata tcatatttgg ggtaaatgta gtatatggta ttcaatggtt attaagagaa
    22321 ctgatttcaa ctatttcccc ttaatgtgta tggaaactat aacaaaacgc ataagattaa
    22381 ggtttgtgta cctgttctta tgcgttttta taatattgaa gattttcggt aagttttcta
    22441 cttttgcgaa gtctagttta tactcaatga aaatcaaaga gtaaactagc cgtaggttgc
    22501 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa acatggtttt
    22561 gaggttgtag atgaaactga cgaagtcagt aaccatacgt acggcaaggc gacgttgacg
    22621 tggtttgaag agtattagaa tgctttccca accaaaatct ctgcttcgat ggtaatctct
    22681 gtcagttggc tccagtcaat cttgctctgg tcaacgtgaa agaggagagg agtcatactg
    22741 agtagggctt ggagttgttc tgctgtgata gtcttagtca gagaggcagt ttgactagat
    22801 aggatggtaa agtgttcctg gaaatgctcc ttgatatctt ggttagaata ctccttgttt
    22861 gtcagctggt cctgtactct ttgacggatt tctttgaggt gattttcagt tgggataacc
    22921 tttatcaaga taccgtcttt ggataaaacg cgacgaaatt ctccatagtt ggcaggtgag
    22981 aagatatcaa gcagaatatc catgttagcg tcttttatag gaaggcgtgc caagtcgcca
    23041 acgaaccaat tgactgccca gttgggttca cttttagcag cgatttggac tgaatctttg
    23101 gagatatcaa aggcatagaa agttttttca gagtgacttt cttgtagttt gcgagaatag
    23161 aatccttcac cacaaccgat atccaaaatt gttgtggtag tttttgagct tgcaagcaag
    23221 tcagatacag catctaagat agcttggtaa aagccggctt ctaggatttg ttgacggttt
    23281 tgaaaatttt ccttgtcata gttagcagat tgcttgattt gaggtgctag attgacatag
    23341 ccaaatttcg ccaagtcaaa agaatgacgg ttgcagcact tgaaattagt ctctaacaga
    23401 gtcagatttt cttgacagat aggacaggca aaggcagtcg cagaagcaaa acgctgaagt
    23461 ttgggcttga gatttgtatt catagtttaa gtgtatcaaa agaggcaaat gaaagcaact
    23521 ttaggaataa gtagatggga gattcagtag aaataaaact aattctccaa tttatagaat
    23581 gaaattgctt ttatatctaa attgctatat aataatgata aggaggaaat aagtatgtta
    23641 aaagaagtat taaccgttgc aaaagttgcg aaaaaatctt cattattttt gggtggtgtc
    23701 gcatttggta cccttggttt gaaaatctta gcaagtaagg aagctaaaaa aggttattct
    23761 aaagctttgg ctaaggctta caagttgaaa gacgagctag atgcatctgt ttctgttgtg
    23821 aagcaacatg gagacgatgt cttgcaagat gccaaatatt tgtacgagca agagaaaaaa
    23881 gaagagcaat tagatagcct tataggtgaa taatatgtct tttaaagtgc tacatagagg
    23941 ataccaacat atccgactat catcttcttt ttcacttacc ttggatattc aagactatct
    24001 tcgttccttg gcgagagatg aaaaggggat tgagtctatc cagttttaca tggatcaaca
    24061 gcactttact ctacgcataa aagaaggctt ttctgtatta gataatgcag aagccttttt
    24121 aaaaagaatt gataaaggga aagtttctga gttgatgact cttcccattc gtagagaaga
    24181 gagtgcttat tctattgttt caggtgcagc ggttaagcgt gtactttttc gtagttttgt
    24241 gccgtatcct attcgctata tatggacttg ttatcaggct ttgggttata ttagagaagc
    24301 ctatcaaaca ctagcgcgta aggaactaac tatggaagtc ttggactgtt cggctatttt
    24361 attgtctttg tttatgaacc aatccaagac agctagcaat atcatgttta tgcttgattt
    24421 ggggaatcat ttagatcagt ggtccttgaa aaaaactgca acagatttag aacagagtct
    24481 tcttgcaaaa gagagcgatg tattcctagt acagggcgat acggttgtta gtataaagag
    24541 ttccgatgtt caaataggag atgtcttgat cttatctcaa ggaaatgaaa ttctgtttga
    24601 tgggcaagta gtttcaggtt taggtatggt caacgaaagt tccttgacag gagagagttt
    24661 tccagttgaa aaaagagagt ctgatttggt ttgtgcaaat acagtattag aaactggaga
    24721 gttacgcatt cgtgtaacag ataatcagat gaacagccgt attttacagc tgattgagtt
    24781 gatgaagaaa tctgaagaaa acaagaaaac gaaacaacgc tatttcatca agatggcgga
    24841 taaagtcgtc aaatataatt tcttgggggc tgggctgact tacctattga caggttcttt
    24901 ttctaaggct atttctttcc tattggtcga tttctcctgc gctttgaaaa tctctactcc
    24961 tgtagcttat ttgacagtta tcaaggaggg gttgaaccgt gaaatggtga ttaaggatgg
    25021 agatgttctg gagaaatatc tggaagttga tactttcttg tttgataaga caggaacaat
    25081 cacaactagt tatcctatag ttgaaaaggt gttacctttt ggagactata gtgaggaaga
    25141 tattctcaga atcagtgcct gtcttgagga acacatttat catcctattg ctaatgccat
    25201 cgtcaagcaa gctgagatag agggaattga acatgaggaa atgcatggga aactccaata
    25261 tatcgcaagc aaggggatca aatctcatat agatggccaa ccagttctta ttgggaatta
    25321 tgtcttgatg caggatgagc agattcatat cagttcagaa caaaatgctt taattgaaga
    25381 gtacaagagt cactacaatc tcttattctt ggcttatcaa aatgaattga ttggaatgtt
    25441 ctgcattcat actcctttga gaaaagaagc aaaaacagcc ttggataaac ttaaggcaca
    25501 ggggaaaaaa ttgattctgg caacaggaga caccttgatt aggacagagg aattagtcaa
    25561 agatttgccc tttgatcagg tctatacaga cttgaaacct gatggaaaat ttgagttagt
    25621 agagaaactg cagaaagcag gtcacactat tttgatggtt ggagatggat tgaatgactc
    25681 agcggctcta actctatcag atatcggtgt ggtgatgaat gagagtgcag atatttctaa
    25741 gcagatgagt gatatcttat tgttagataa tcgtttggat ttcttccaag agttggattc
    25801 gttatcatca tctttgcaaa cactcatcaa gaaaaatatt caagataccg ttgtcgtaaa
    25861 tagtagtttg attggcttcg gcttatttaa ttggctcagt ccttcaaatc tctctatctt
    25921 acataatcta acaaccttgc gcattgtcct gcgtagcctg tctattaaaa atagatagat
    25981 gagagttatt aacagcaaaa aggagttacc tttctcgagg ttaactcctt tgtttataga
    26041 taaatgttga atagtttagt aagtcaatac aaagtatttt ttcttcccac gacggataac
    26101 agtcagttca ttttctaact tatcagcgtc actcaagaca tagtcaagct cttggatgcg
    26161 gtcgccgttt acgtagatgg ctccgttttg gacgtcttca cgggcttggc gttttgagtt
    26221 aactatacca gatgagacga gcagttccac gatattgttg ttttcgtctg cctgtacttg
    26281 gtagtttggc acaccacgaa gtccttgttt gagctctttg acagaaaggt ttttgatgtt
    26341 tcctgcaaag agttgctcag tgatgttaag tgcttctttg taggcttctt ctccgtgaac
    26401 aagtgtaaca acttcacgag ccaagacttt ttgagccaag cgttcgtgtg gcgctgcttc
    26461 aaattgttta cgaatatctt caatctcatc aagtgacaag aaagtaaaga ttttcaagaa
    26521 gcgaacagcg tcagcgtcca tcacgttcat ccagaattgg tacatttcgt atggagaagt
    26581 cttttcggga ttgagccaga cggcatttcc ttctgattta ccaaatttct taccagttgc
    26641 atctgtgatt agtggaacag tgataacgtg accagtcttg tccgccttac gacgaagcaa
    26701 ttcggtacca gctgtcatat ttccccactg gtcagaacca ccgatttgaa gagtgacatt
    26761 atggtcttgg ttaaggacga agaagtcata cccttgcatg atttggtaag cgaactcagt
    26821 gtaagaaatt cctgtttcga tccgtttttt aacagattcc ttactcatca tgtagttgac
    26881 cgtgaagtat tttccaatat cacggaggaa gtcaatgaag ctgatgctgc caaaccagtc
    26941 gtagttgttg accatgacag ccttgttttc gccattttca aagtcaagaa aacgagaaag
    27001 ttgtccttgg atagacttga cccagccatc tactgtgtct tttgtttgga gactacgttc
    27061 agcatctttg aaggacggat ctccgatgag acctgtagca ccgccaacga gcgcataagg
    27121 tttgtgacct gctagttgca agcgacgact tgtcaagatt gcgacaaggt ggcctaggtg
    27181 aaggctgtca gcagttggat cgtagccagt ataataagaa acttgacctt cttctagggc
    27241 tttacgcaaa gcttcttcat cagtcgtttg aaatatcaaa ccacgctctt ttagctcatc
    27301 aaaaatgtgc atgtgttttt tctccttttt aaaattattg tttctaccta ttgtatcaca
    27361 aacttgggca atagcctagc agaataggga agaaagtggc tattttattg aaaatttccc
    27421 ttttgtggta taatagataa agtgaggaaa tccatgcaaa atcaattaaa tgaattaaaa
    27481 cgaaaaatgc tggaattttt ccagcaaaaa caaaaaaata aaaaatcagc tagacctggc
    27541 aagaaaggtt caagtaccaa aaaatctaaa accttagata agtcagccat tttcccagct
    27601 attttactga gtataaaagc cttatttaac ttactctttg tactcggttt tctaggagga
    27661 atgttgggag ctgggattgc tttggggtac ggagtggcct tatttgacaa ggttcgggtg
    27721 cctcagacag aagaattggt gaatcaggtc aaggacatct cttctatttc agagattacc
    27781 tattcggacg ggacggtgat tgcttccata gagagtgatt tgttgcgcac ttctatctca
    27841 tctgagcaaa tttcggaaaa tctgaagaag gctatcattg cgacagaaga tgaacacttt
    27901 aaagaacata agggtgtagt acccaaggcg gtgattcgtg cgaccttggg gaaatttgta
    27961 ggtttgggtt cctctagtgg gggttcaacc ttgacccagc aactaattaa acagcaggtg
    28021 gttggggatg cgccgacctt ggctcgtaag gcggcagaga ttgtggatgc tcttgccttg
    28081 gaacgcgcca tgaataaaga tgagatttta acgacctatc tcaatgtggc tccctttggc
    28141 cgaaataata agggacagaa tattgcaggg gctcggcaag cagctgaggg aattttcggt
    28201 gtagatgcca gtcagttgac tgttcctcaa gcagcatttt tagcaggact tccacagagt
    28261 cccattactt actctcctta tgaaaatact ggggagttga agagtgatga agacctagaa
    28321 attggcttaa gacgggctaa ggcagttctt tacagtatgt atcgtacagg tgcattaagc
    28381 aaagacgagt attctcagta caaggattat gaccttaaac aggacttttt accatcgggc
    28441 acggttacag gaatttcacg agactattta tactttacaa ctttggcaga agctcaagaa
    28501 cgtatgtatg actatctagc tcagagagac aatgtctccg ctaaggagtt gaaaaatgag
    28561 gcaactcaga agttttatcg agatttggca gccaaggaaa ttgaaaatgg tggttataag
    28621 attactacta ccatagatca gaaaattcat tctgccatgc aaagtgcggt tgctgattat
    28681 ggctatcttt tagacgatgg aacaggtcgt gtagaagtag ggaatgtctt gatggacaac
    28741 caaacaggtg ctattctagg ctttgtaggt ggtcgtaatt atcaagaaaa tcaaaataat
    28801 catgcctttg ataccaaacg ttcgccagct tctactacca agcccttgct ggcctacggt
    28861 attgctattg accagggctt gatgggaagt gaaacgattc tatctaacta tccaacaaac
    28921 tttgctaatg gcaatccgat tatgtatgct aatagcaagg gaacaggaat gatgaccttg
    28981 ggagaagctc tgaactactc atggaatatc cctgcttact ggacctatcg tatgctccgt
    29041 gaaaatggtg ttgatgtcaa gggttatatg gaaaagatgg gttacgagat tcctgagtac
    29101 ggtattgaga gcttgccaat gggtggtggt attgaagtca cagttgccca gcataccaat
    29161 ggctatcaga ccttagctaa taatggagtt tatcatcaga agcatgtgat ttcaaagatt
    29221 gaagcagcag atggtagagt ggtgtatgag tatcaggata aaccggttca agtctattca
    29281 aaagctactg cgacgattat gcagggattg ctacgagaag ttctatcctc tcgtgtgaca
    29341 acaaccttca agtctaacct gacttcttta aatcctactc tggctaatgc agattggatt
    29401 gggaagactg gtacaaccaa ccaagacgaa aatatgtggc tcatgctttc gacacctaga
    29461 ttaaccctag gtggctggat tgggcatgat gataatcatt cattgtcacg tagagcaggt
    29521 tattctaata actctaatta catggctcat ctggtaaatg cgattcagca agcttcccca
    29581 agcatttggg ggaacgagcg ctttgcttta gatcctagtg tagtgaaatc ggaagtcttg
    29641 aaatcaacag gtcaaaaacc agggaaggtt tctgttgaag gaaaagaggt agaggtcaca
    29701 ggttcgactg ttaccagcta ttgggctaat aagtcaggag cgccagcgac aagttatcgc
    29761 tttgctattg gcggaagtga tgcggattat cagaatgctt ggtctagtat tgtggggagt
    29821 ctaccaactc catccagctc cagcagttca agtagtagtt ctagcgatag cagtaactca
    29881 agtactacac gaccttcttc ttcaagggcg agacgataat tctctaaatg aagtggccaa
    29941 tcaatggatt gccacttttt tcttttcgtg ttacaataag ggtatgaatc agtatcagaa
    30001 aaagattgtt aacggaaaaa tttattcgct cctatccggc ttaatatggg gaatctgtgg
    30061 aattttagga gagtacttct ttactcatta tcaggtgtct tcgggctgga ttacctctat
    30121 gcgtttgaca ctggcaggga gtcttgtact catttggtct gcaatacaat taaaatcgca
    30181 agtgctagat atttggcgag acaagaaaaa ttacctgccc tttttagcct atgctatttt
    30241 ggggattttt tcagttcagt attttttcta tctctgtgta gaatactcaa atgctacgac
    30301 agcaactatt ttacagttta ttagccctgt ctttatcctc ttttacaatc gcttggttta
    30361 tcaaaaacga gcgtcaaaaa gcgctgtttt ctatgttttg gttgccatgc tgggtgtttg
    30421 cttgatggcg acaaagggag atctctctca gttatccatg acgccgctag ctcttataac
    30481 aggtttgctg agtgccatgg gtgttatgtt taatgttatc ttgccccaac cttttgctaa
    30541 gcgttatggt tttgttccta cggttgggtg ggggatgatt ttggcaggtt tgtttagcaa
    30601 tgtcctctcg ccggtttatc agctttcctt tactcttgat atttggagta tcttgatttg
    30661 cctcattatc gctttctttg gaacggcttt tgcttttttc atttccatga aggctgtgtc
    30721 cttggtttct cctttggtgg ttgccgttat cagtgccagt gaacctctct cttctgctct
    30781 cttgagtgtt ttgttcttag gattagtagt ggattggtcc ctccttctag ctatagcctt
    30841 gattatttta cccatgatat ttttgtctat agaagaagcg aaagaaagta gataaaaagt
    30901 cttttcttaa ttctaaaagt gtgctatact agaatagtca ataaaacacg gggagatagt
    30961 tgtgaagagt gtttttaggt tgtatcggta ggggcttgct tttaccgaca gcacgtttta
    31021 tctcacaacc ctaaaaaatc atacctaaaa acagacaaaa aggtttcaaa tttgaggcct
    31081 tttttggtag aataggtatc attataacga accaggaggc acctatgact gctacaaaaa
    31141 tgaacgctca agaaattatc caatttatcg ccaatgctga aaagaaaacc agtgtcaaag
    31201 taacctttga ggggcaactc gcaactgctg tgcctagctc tgttgtcaaa ctaggaaatg
    31261 tcctattcgg agactggaag gacgtggctc cgcttcttga aggtttggta gaaaatcaag
    31321 attatgttgt cgagcaagat gctcgtaatt ctgcagttcc tttgctagat aagcgtgcta
    31381 tcaacgctcg tatcgagcca ggtgctatta tccgtgacca ggtggaaatt ggtgacaatg
    31441 ctgttatcat gatgggagct gttatcaata tcggtgctga aatcggtgct ggaaccatga
    31501 ttgacatggg tgccatcctt ggtggccgtg ccatcgttgg aaaaaatagc cacgttggtg
    31561 caggtgcagt tttggcaggt gtgattgagc cagctagtgc tgaaccagtc cgtgtcggag
    31621 acaatgttct tatcggtgct aatgcagtgg ttatcgaagg agtccaaatc ggtagtggtt
    31681 cagttgtcgc tgcaggagct atcgttaccc aagatgtccc agaaaacgtg gtagtagcag
    31741 gtgttccagc tcgtatcatc aaagaaattg atgcccaaac ccaacaaaaa acagcgctag
    31801 aggatgcgct tcgtaccttg taattgtaaa agtaaaaaag aggcggaacc ctttttccag
    31861 cctctttctg ctatatcgga ggacagatag atgttagatt tgattcagac tagacgagct
    31921 ttacaccaga ttccagagat tggcttggag gagttcaaga ctcaggctta tttgctggat
    31981 gtgattgaga aattgactac gggcaaggat tttgttcaaa ttcgtacttg gcggacaggg
    32041 attttggtct acctgcaggg aagtcagccg gagcgaacca ttggttggcg gacagatatt
    32101 gatggtctgc ctatcgtcga acaaacaggt ctaccttttg cttctcaaca ccaaggtcgc
    32161 atgcatgcct gtggtcatga ttttcatatg accattgcct taggctgtct tgagcgcgcc
    32221 cttgaggagc aacccaagaa taatctgctc tttctatttc agcctgctga agaaaatgaa
    32281 gctggtggta tgctcatgta tgaggacggt gcttttggag attggttgcc agatcaattc
    32341 tatggtctcc atgttcgtcc agatttgaaa gtcggccaga ttgcgactaa tactcataca
    32401 ctctttgcag gaacttgcga ggtgaagatc cgtttcaaag gcaaaggtgg ccacgcagct
    32461 tttcctcatg aagccaatga cgccttggtg gcggctagtt actttgtgac ccaagtgcag
    32521 tcagttgtta gccgcaatgt caacccaatc gagggagcag tggtgacctt cggcgttttt
    32581 caagctggaa ccaccaacaa tgtcatcaca gacacagctt ttttacatgg aactattcgt
    32641 gccttgacac aggacatgag tctcttggtg caaaagaggg taaaaacagt tgcagaaggg
    32701 gttgcagctg cctttgatat ggaagtcgaa gtggaactca aacaaggtgg atacctacct
    32761 gttgagaaca atccagcctt ggcgcgtgaa ctgatggact tctttgacga aaaagacgga
    32821 atcgagttga ttgatatcga acctgctatg acaggcgagg actttggtta tctcctttca
    32881 aaggttgatg gcgtgatgtt ttggctaggt atcgatagtc cctacgctct tcatcaccct
    32941 caaatgagtc ctaaggaaga agtcttagct attggggtgg ctgcggtgtc tagtttcctg
    33001 aaaaagaagg cagcagaata gagggcttgt ctatgaaatc ggaattacgc aagcaagtct
    33061 tgcatgaaat gaaggcttta tctcaagaac aaaaacaggc tatagaccaa gctttaaccg
    33121 agcgaatttt acaacacccc ttttatcaag aagccaaggt catcgcaacc tacctctctt
    33181 tttctcatga gtttcaaacg cgggaactga ttgagcaggc gctgaaggac ggcaagaagg
    33241 ttttgacacc taagacctat cccaaggggc gcatggactt tgtagtctat gatccgcagc
    33301 agttggtaaa aactgccttt gccttactgg agccacaggg agatttggaa gtggtggatg
    33361 tatctcagat tgatttgatt catgttcctg gcctggcttt tacgacggat ggatatcgga
    33421 ttggatatgg tggaggttat tatgaccgct atctggaaca tttttctggt catactttga
    33481 gtacggttca tccttgtcaa attcaggact ttatacctga aaaccatgat attcctgttc
    33541 aggaggtatt aattgatgaa ggaaatcttt gatagacgtt accctgtgac gagtttcttc
    33601 ctcttagtga cggccttggt atttttacta atgttggtca ctgcaggcgg aaactttgac
    33661 agggcagata cattatttcg atttggagcc atgtatgggc cagctattcg cctctttccc
    33721 gagcaggttt ggcgtctctt gtctgccatt tttgttcata ttgggtggga acatttcatt
    33781 gttaatatgc tttcacttta ttatcttgga aggcaggtag aggagatttt cggctctaag
    33841 cagttctttt ttctctatct cttatcagga atgatgggca atctctttgt ttttgtattt
    33901 agtcctaaat ccttagcagc aggcgcctct acctctcttt atgggctatt tgccgcgatt
    33961 attgttcttc gctatgcaac tcgcaatcct tatatccaac agctagggca atcctatctg
    34021 acactttttg tggttaacat tattggaagt gttctgattc caggaatcag cctagcaggc
    34081 catatcggtg gtgcagttgg tggcgcattt ctagcagtta tctttccagt tagaggagaa
    34141 aaacggatgt ataacaccag ccagagatta ggagcggtag tcttgttcgt aggactcgcc
    34201 attttgcttt tctacaaggg aatgggaatg tgacgaagtt gaaagaaaat ttgtgtaatg
    34261 aaaaaagata aggcattttt tgaaccttat ctttttattt tattccttct cagtcaattc
    34321 ttttccaagt tggatgaggt aattcttcaa atcatctttg acttgtggat gtttgagggc
    34381 gtagtcaata gatgttttca taaagccaaa cttatcccca acgtcgtaac gagctcctgt
    34441 aaattcacgg gcaaaaacac gctgtgtttt attaagagta tcgattgcat cagtaagttg
    34501 gatttcattt ccagcaccag gagcttggtt ttcgaggatt tggaaaattt caggcgtgag
    34561 gaggtagcgt ccgataatag caaggtcgct aggagcgtcc tctggagctg gtttttcaac
    34621 aaaggtttca acactgtaaa gaccatcttt tccttcgcct tgcggagcaa taaccccgta
    34681 agcagatact tcgtcatgag ggactggcat gacagcgata gtagacgcgt gggtacgctc
    34741 gtagtcatcc atgagttgtt tggtaagtgg aacagccttt tcgtctgtga tatccatcaa
    34801 gtcatcacca agcataacga caaaaggttc atttccgacg aaagccttgg cttgcaaaac
    34861 agcatctccg agaccgcgtg gatgagtttg gcggataaaa tgcagccgca tgtcagttgt
    34921 tttatcaact agcttcaaaa gatctgtttt ccctttttct ttgaggttat attccaattc
    34981 gaagtttgaa tcaaagtggt cctcaataga acgttttgat ttaccagtga caactagaat
    35041 atcttcaata cctgatttga gagcttcttc cacgataaac tggatagttg gtttgtctac
    35101 gattggcaac atttctttgg caagggcctt ggttgctggt aaaaatcgag ttcctagtcc
    35161 agcagcaggg atgactgcct ttctaacttt tgatgtcata aaaatccttt ctatagaggg
    35221 ttaagaccac tcattttctg ctttaaattc attgttcatg atgtcataaa tggcatcttt
    35281 gatattggtt ccgtgataaa taacttggta aatagcctgt gtaatgggca tatagactcc
    35341 aagttcttgg gctagttcat aggctgctcg agtcgttgaa attccttcga ttaccatgcc
    35401 catattagct tctatatcag ctagggattc tcctcgtccg agagcatctc cagctctcca
    35461 gttacgagag tggatggaag ttcccgttac gatcaaatct cccacaccag ataagccgct
    35521 ataggtcaat ggactggccc cgagtgctac ccctaggcgg gtgatttctg ctaaacctcg
    35581 agcgatgatg gctgccttag cattatcacc aaatccaaga ccatgtaaag ctccagcacc
    35641 gacagcaata atatttttaa gagcaccagc agtttcaacc ccgataacat ccgtattggt
    35701 ataaagtcgg aagtagtgat tactaaatag cttctgaacg tattgagctg tttgtaaatc
    35761 tttagaagca gcagttatta aagttaggtc acgcacaatg gtctcttctg catgactagg
    35821 ccctgaaaca acgacgatat cactacggag atgttcagga atttcttctt caagaatggt
    35881 tgataatcgt ttatggctat caggttctaa tccctttgat gcgtgcatga tgataacctt
    35941 atggtccaag gtttgtgcaa cttgctgggc aacaagtcgt gtcacttttg ttgggacaac
    36001 aaacaaaatc gcatccacat ctttcaatgt ttctgctaag tcggtgtagg caatgatatt
    36061 ttcgtctaga acgacatctt taaagtagtg cttattagta tggtgtgtat taatttcatt
    36121 gatttgctcg ggaagatttc cccaaatacg tacctcgtgt ccattgtcat ttaagacttg
    36181 tgaaagggcg gttccccaag aaccaggccc caagacggcg acggtttgtt tttccatgat
    36241 ttcctccttg atagagttct ttctcttatt ctatcatatt ctaggggatt ttgcacttgc
    36301 attactgggg tatggtggaa aaatacacaa aaaccgagac gaagggataa actcttagtc
    36361 tttagttaaa gtgagaagaa atctgataga tagtttgatt cagtatatgc ttataataga
    36421 ggtaaacaac tcaggaggtt cttgtaggtt gcgagagttt ggcgaaaaaa ttaaaagatt
    36481 acgtttggct aaaaaaatca gtcgttcaga attttgtggt gatgagtctg aattaagtat
    36541 ccgtcaatta attagaattg aaaatggaga atccagacca atactaacaa agttaaaata
    36601 tattgctgaa cgtttggagg ttgaagatta caagttgatg ccaagttata tagagttgga
    36661 taaggaatac ctagaattga agtatttctt gatgaggact cctacatacg aagatgaaac
    36721 tatcgcccaa aagaaagaga gtgtttttga taagattttt gaagagtatt atgataggct
    36781 acctgaggaa gaaagattta tcatcccaaa ttattcatat ctggcactaa cgaactacac
    36841 agttcaaaaa ttaccagaaa agctagttga aatactgtcc ttctggtgat tttgcttaat
    36901 ttctgatgtt cgagacatga ttgaggagat ttgtcttgat tttttcctaa aaaagggcag
    36961 actcctccct tggtttgatg ctcgattttt aaaataaggt gacttattct gttaggcatg
    37021 ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc tggcagattg
    37081 tatcaaataa ggcttgaaac tgttttgaat aggcatatag acttgagaat ttgagaatat
    37141 gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt cgaaaacgct
    37201 tgatagtcaa ggcctttact tcatcaccag ctagctgctt taaaaagagg tagagattat
    37261 aagccagaca gcccatcatc atacgtactt cattcttaat catggtcgaa ctatctgtct
    37321 tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc cctcgttcac
    37381 gatagaattg aaacagctcc tcactatcta cactgcttaa attggtcaaa tgaacttttt
    37441 tacaaccata aaaaagagca cttaatcgta ctcttctctt ttaaggatta gttgaattaa
    37501 ttcaaatcca ctagttctcc tgtttctagg tagactaggc gttcacaaat gttagcaatg
    37561 taatcagcga agcgttccag atgccctatg atataaaggt attgagttcc attgggaatt
    37621 gaggtttctt ggtctttcat aagtccaatg atttcctttg ataaggcata ataatattgg
    37681 tcaatctgtt catctttttg agcaatacta atagcttttg aggcttggtg caaaggaaag
    37741 gcaaccaata aatcggctag catgctgagg gataatttac ccatttggtg taactgttct
    37801 tcgtcagggg ctagttgatt ttcttttagt tgcaaaacag ctttggcaat gcctgccata
    37861 tggtctccca tacgttcaag gtctgaacaa gaagacatga tgctaatcac aaatcgaagg
    37921 tcagacactt gtggctgctg caaggccaac aaacgggcac aggtcaattc gatagcgctt
    37981 tgaccttggt tgatagcatg atccttattg ataattagct ctgccatctc cttgtctttg
    38041 gaggctaagg ccagtaaggc ttttgaagct gtttcaagga caagttgccc tagtcctaaa
    38101 aaggattgtt ctaattcatg caattctaag tcaaattgat ttctcatagg tttttccttc
    38161 cttatccgaa ccgtcctgaa atatagtctt ctgtgcgctg atcttttgga ttggtaaaca
    38221 cgtcaacggt atctccaaat tcgcaaattt ctcctgttaa gaaaaaagca gttttatctg
    38281 aaatacgtga agcttgttgc atgttatggg taacaatgat aatcgtataa tcctttttta
    38341 gttgctgaat gaggtcttca atttttaaag tggagatagg gtctaaggct gaagtcggct
    38401 catccattaa cagaatatca ggttctactg ctaaagctcg cgcaatgcaa aggcgttgct
    38461 gctgaccgcc agataaggac atggcactct ttttaagatc atctttgact tcttcccaaa
    38521 tggctgcccc ttttaaagat ttctccacta aggcatctaa ttgttttttg tctcgaatac
    38581 catgtgtcct tgggccataa gccacgttat catagataga catggcaaag ggattaggct
    38641 gttgaaaaac catccctaca cgcttacgta gctgattaag gttgaatttg ctactataaa
    38701 tatcttgctc atctaagagg acttggcctt caatatggca agaaggaacc aaatcgttca
    38761 tccggttaag ggtttttaga aaagttgatt tgccacaacc agatgggcct atcaaggcag
    38821 taatctgtct ttctggtaat tgaatcgaaa tattttttaa ggcttgaaaa tccccgtaaa
    38881 ataagtctag gtgtctgact gaaaatgttc ccatactagg aagctccttt cacaagtttt
    38941 cgagataata agcttgatag agtatttatc attaaaacag taataatcaa aatcacaccg
    39001 gtagcatagg cttcattgac atgtagcccc tcacttgaca gcatatacat atgcagggct
    39061 agagaacgac ctgaagacat gagactactt ggcgtattgg tagaggtacc taatgtatac
    39121 atgagggcag ctgtctcacc aacgatacgg ccaatagcta gtatcactcc agctaaaata
    39181 cctggcatgg caactggtag aacaattcta aaaacagtcc gtaacttacc tgccccaagt
    39241 ccataacttg cttgacgcat gctatcacta acagataaaa gggcttcttc tgttgagcga
    39301 ataatgactg gcaacaccat gatgactgag gttaagattc ctgataacag agagtattga
    39361 aaacctaaga agactacaaa gaagagcatg ccaaacagac caaaaacaat ggaaggaatc
    39421 ccagacaagg tatctgaggc caatcgcatg attttaacac aaagggaatc tttttttgta
    39481 tattccacaa gataaaaacc agcaaaaatc cctatgggca aggctaaaag aagagcacca
    39541 aagaccagaa taacggtgga aataatcgct ggcataaggg aaatgttctc agaagtataa
    39601 gtccaagaaa agagggatag acttagatga ggtaagcctt tgatgaggat aaaaccaatg
    39661 attaaaaaga gagagccaaa ggttaaagct gaaaaacaat aaacgagaag ttttagcagg
    39721 tatttactca taagatgatt ttcctttcaa gtaggcaaag taggcattaa tcaagagaat
    39781 aaggaaaaag agaactgctg aggttgcaat aagggcttcc ctatgctgac ctgatgcgta
    39841 agccatttcc agaacaatat tggttgttaa ggttctggtt cctgaaaaga gtccacttgg
    39901 aataatcggc tggttgcctg ccaccaaaat aactgccatg gtttcaccta ctgcgcgacc
    39961 gattcctaaa ataactgctg ataaaatacc agatctcgca gctggcaaga tgacactaaa
    40021 aatactccgt tcatgactag ctcctagagc caagctacca gaataatacg ttttgggaac
    40081 tgttcggata gcagattctg acaaactgat aatggttggc aaaatcatta ttcctaatag
    40141 taacgaagcg gttaggacac tcatgccatt tcctaaaaag cttctaatcc aaggcaccaa
    40201 taattgtagg ccgaaaaaac cataaacaat agatggaatg gccgccatca agttgatagc
    40261 tgattttaag aagccataga cgggctttgg acaataataa accataaaca ccgatgtcaa
    40321 gatgcctgtt ggcaccccaa tcacaatcgc tcctaaggta attaataagg aaccaacgat
    40381 cattggtaaa ataccatagc ttgccggaat gttcgttggc gaccaatcac tgcctaataa
    40441 aaaacgggca aagccgtagt tagccatgaa aggtaagcca ttactaaaaa taaagaaaca
    40501 gattagcaaa atagctacaa cagctactgt tgcactcatg aaaaaaattg ccctaaaaac
    40561 tgcttctttg aaggcttgtt ttgtcacatc ttgtcctttc tagtgaagaa agtaagggag
    40621 atacgacacc tccctacttg ccttctttat cttattgtac gatgaaacgt ctgcatctct
    40681 ttagagattt atggagcaaa cattttattt aatcttgtcc caggtggtta atttgccact
    40741 aaaaacgtct gcaagttcag ccatactgac ttggcttgcc ttattgtcat tattgaccac
    40801 aacagcaata ccgtctaaag caatagcatc atgggtgaga ctcttacctt cttcaggagt
    40861 taattcccta gaaaccatac caatatcagc ggttttctcc ttaacagcgg taatacctgc
    40921 tgaagaccca ttagaggtaa tatcaatcgt aacttctgga ttttcttttt tataagcttc
    40981 tgctaatttt tccattaaag aagatactga agtggaacct acaacagaca acttgcctga
    41041 taagtgttgg cttgtatatt ctgtggtttc agttttagct tcaataaatt tattatctgt
    41101 gaccacttgt tgaccttgtt tggagtggat aaagctgata aaatcttgac ctagcttgga
    41161 aagattagaa gaccaaacaa tgttgaaggg acgttgaaga gggtattcac catctaaaac
    41221 tgtgtctcga ctagccttga caccatcaat ctctaaagct ttgacagatt tcgttaaaga
    41281 tcccaaggag atgtagccga tagcattagc attcccttga actgctgaga gaacaccttc
    41341 tgtactattt tgaatcacag ctgttttggc agtgttgtca atttttttat caccgtcttt
    41401 tttgagaatc cctgtgattt ctgtgaaggc accccgtgtt ccagagccat tttctcgtga
    41461 aatcacctca atcgttcctg aagctgactg tttggaagca gctgactgat tgccacaggc
    41521 aacaagccca aatcctgata agccaatggc tgcaagagta agcatttttt tgaatttcat
    41581 aataatcacc tttatctcta tgtatttttc ttgtgtaggc ttactacatt tatagtctaa
    41641 caagtctttg taaaggttta tccctgattc atgtaaagat tgtgtaaaga atcaaaaaaa
    41701 gccacttttg aaaaatggct gctcctaaaa atagctttaa aaattattag tcctgtgcga
    41761 aagattggtt aggaagaaaa atcgtgaagc aactgcctct gccaagctga ctcgtcaccg
    41821 tgacttggcc acctaataat tgactgagtt ctttgacaat ggcaaggcca agaccagtgc
    41881 caccagtttg tctgcttcga cctttattaa ctcggtaaaa acgttcaaaa atacgatcct
    41941 gctctaattg actaatacca atccctgtat ctgatacaga aatcttaatg ccttcgttca
    42001 ccttttgggt cttgacctca atttttcccc cttgttcagt gtaacggatg gcattggata
    42061 aaagattgag taagatttgg gaaagtaatt gactatctga tacgagggtg acatcatctg
    42121 gcacctgcac ctttagctgt aaatccttct tcttgagctg aggttgcaag ctttgagtca
    42181 aatcctgtac aaattctgcc aaagaaaggg tcgtccattg tataggcatt tgttgagcct
    42241 tagataaggt aagaagatgc tcaacaatat gctcaagacg caagctttct ttgtaaataa
    42301 tgtctagaaa gtcatccttg agcgcttctt cttcagctga catcccctta atggtttcag
    42361 caaagccctt aatcgaagta actggtgtcc tcaattcatg ggaggcattt gagacaaagg
    42421 ctaaatttaa cttttcataa gttctaatcg ttgttaaatc atatagcaag acgagcacag
    42481 cttccacaga ttgggtgggg ctaaaaacgg gaactgctgt cacttctaaa atcaagtcac
    42541 cctcatgaaa cccacttact tcttgtttta accttgtttt ttgatcaaag gcttggtgaa
    42601 ctaaatttcg aatatccatc cgtttgaggt catcaagtga acttatgtcg ccgtccacat
    42661 cgggaaaata atgaggcaga gagcgactgg ataataacat ctgaccttga gcggaaacta
    42721 aaaacgtccc catggttagg tgcgacagaa gaacctccat tgtttcggct aggtccttgt
    42781 attgctgatc ctgttgggag actttggttt ttagggcaga cacatactga gccaaagact
    42841 ttaagtcttc ttgccctttt tctaaaaagt attcactact ggtcaagaga ggttggtgca
    42901 aggtctcaaa agcaacttcc catttccaaa ggcaaaagag ccagtagcca ccttgtccca
    42961 aagaaagggc tagaagaaag agaccgatgc ctttactgat ccaagttaat gccatccctg
    43021 caatcagaat gaggctaaca cttagattga ctagccaaaa ttgaaggtag cgtttcatct
    43081 ataactcctt gaacttataa ccataacccc gaatggttcg aataaattga ggggctttag
    43141 gattgtcttc aattttttcc ctcaacttac caatatgaac gtccaccaaa cgtgtttcct
    43201 gcccaaagtc atacccccag atacgttcca aaagacgctc tctagtcagt gtcatgttgg
    43261 gatgtttcat aagatagagc aagagttcaa attcttttgg ggtcaaactc agtaacttat
    43321 tcgccttgta gacttcatga cgctcagggt atactttcaa ggtcccaaat agccaagaat
    43381 cgtcagcgat attatctgaa tcatctcctt cttgttctcc tttagttcgc ctgaggacag
    43441 ccttgacacg cgccagcaat tctctagggc taaaaggttt ggtcaggtag tcatcagccc
    43501 ctaattccaa ggccaaaacc ttatcaaatt catcactttt cgcagaaacc atcataattg
    43561 gagttttgac gcctttggct ctcagccgct tacaaacttc catgccatct aattgtggta
    43621 acatgatatc aagcaagata aaatcaaagg gttctgtttc tgccaaagct aaggccttcc
    43681 gtccatttgt taccaattga gtagaaaagc cttccttact taaatggtag tcaagcaatt
    43741 tcagaatgtg ttcttcatca tccactaata agacttgttt tgtcatctat tatctcctat
    43801 tggtaacatt ataacacaat tatcagaaat cctaacattg ctaaatcaga ttaaatttgc
    43861 ttatcaagac tagtatctgg tcaaacgctc aatcatctcc ttgtgctctg gataggtcgc
    43921 cagtagatct accctttcaa ataattcaaa atcctcaaat tcaaaaccag gagcaacaag
    43981 acaagaaacc agagcatcat ccttatcaac tgttgatccc caaatagtgc ccttaggaac
    44041 acagtagtga agttgttgcc ctttggatat gtccaggcct aaagtgactg cttcgtagtg
    44101 accatctgct gtaatcatgt gaacagtaag tggggattct gcatgaaaat accagatttc
    44161 atctgctgtc aatcggtgaa aatgtgaagg attcgtttct tcttaataag aaataaatac
    44221 tggtataaag cgcccttccc ttaccagcaa ggtttatagt gtctgaagct ttttttgttt
    44281 gtctaaaata gccaccttca acatggggag ctaactctag agttcttatc aagtcttctt
    44341 tatccgtcgg agccaatggg ttgaagtaac tcttgttcaa aggtggtgtt acgatttcaa
    44401 gaactcctct cagctctgag gacacgataa tgattgatgc gacggaagta aaaatcaatc
    44461 gccctaaaaa aacaattagc gaataattct ggtaaaaaga aatttcacgc tatgaaggct
    44521 caagcgattg tcacaagtca agggagaatt gtttctttgg atatcgctgt gaactattgt
    44581 catgatatga agttgttcaa aatgagtcgc agaaatatcg gacaagctgg taaaatcttg
    44641 gctgacagtg gttatcaagg gcccatgaag atatatcctc aagcacaaac tccacgtaaa
    44701 tccagcaaac tcaagccgct aacagttgaa gataaagcct gtaaccatgc gctatctaag
    44761 gagagaagca aggttgagaa tatttttgcc aaagtaaaaa cgtttaaaat gttttcaaca
    44821 acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggcattatc
    44881 aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg tgaattagtg
    44941 aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga ttatatttag
    45001 gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt
    45061 aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat
    45121 ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta
    45181 cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact
    45241 ccaagcaagc gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg
    45301 ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat
    45361 tgagccaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg
    45421 ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc
    45481 aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat agattggata
    45541 cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcttct
    45601 aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt aatggctcca
    45661 accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt agcctcgatt
    45721 tggaccttgg cacggctaac agcctctgca atagtaggct ctagcaagat gacattccct
    45781 ttacgagtag agagcttctt cccttctttt gtaaccagac caaaaggaac gtgggtaatg
    45841 tcgtcactcc aatcgtagcc catctcttgc aagacagctt tgagctgttt aaagtgggca
    45901 gattgttctt gaccaacgac gtagatagat ttagcaaatt ggtattcatt tttacggtag
    45961 agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg
    46021 gctggatgtt caattccgta tttctcaaga ttcacaactt gggcaccttc tgattcaaga
    46081 agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct
    46141 tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact
    46201 aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt
    46261 ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg
    46321 atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg
    46381 ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg
    46441 ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata
    46501 acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg
    46561 ataacaacat tttcttgttt accaatattt tggtcagcat agtgttcttt ttcagtggta
    46621 acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt
    46681 cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag ttcagccgca
    46741 atcatttgtg gtgctttacg ttcgactttt gcaagagaaa aagcagggaa agcaatgtct
    46801 cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg gtccaggcta
    46861 tcaatgatgc tagataattt gctagcaatc aattcttttg tattcattaa gagctccttt
    46921 ttggactttt ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct
    46981 cctgtttttt tggtataata tggttataaa tatagttata aatatgcacg caagaggatt
    47041 ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa
    47101 gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa
    47161 ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt
    47221 attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt
    47281 tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct
    47341 ctgttttggc aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg
    47401 gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc
    47461 gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt
    47521 tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt
    47581 ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg atttttatga
    47641 attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg
    47701 caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca
    47761 gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga
    47821 tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac
    47881 agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca tagaccgcga
    47941 aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg
    48001 tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt
    48061 gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga tgaatctggt
    48121 actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac
    48181 ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga
    48241 attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc agatggatta
    48301 tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag
    48361 tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg
    48421 gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt
    48481 ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga
    48541 cattgagcgc ttggctagtc gtgtttcttt tggtaaaacc aatccaaagg atctcttgca
    48601 gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag ggatggagca
    48661 acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat
    48721 tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac
    48781 tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat
    48841 tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta
    48901 caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa atgtgccagc
    48961 ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc
    49021 ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat
    49081 atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag ctctagccca
    49141 aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt
    49201 gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc gccatgctgt
    49261 cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga
    49321 taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct atatgcgtca
    49381 gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg aaagcgccca
    49441 tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg
    49501 tcagtcaacc tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa
    49561 gaactctctc attctctttg atgaattggg acgtggaact gcaacttatg acgggatggc
    49621 tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc
    49681 gacccactac catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca
    49741 cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg aaccgggacc
    49801 agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt
    49861 agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc
    49921 catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca
    49981 tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat
    50041 gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc
    50101 tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa
    50161 cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt
    50221 atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca
    50281 ggcttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc
    50341 ctccttgctg ggaaatatga agctatttat agtatcgggg cttggttgat tggtgtggcc
    50401 gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga
    50461 gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc ttatgctgat
    50521 attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt
    50581 cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt gttcatcggt
    50641 tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt tctcatggta
    50701 gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgccaag
    50761 tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt
    50821 gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac
    50881 gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga accctttatg
    50941 atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag
    51001 tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagattatc
    51061 tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg
    51121 cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat
    51181 gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc aatggacaag
    51241 gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt
    51301 ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca
    51361 caggaagggg ctatcaaaat cggaggtaag gatattcgag aagtgagtga aggaaccctg
    51421 cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat
    51481 aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc agccaatatt
    51541 gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa
    51601 cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc
    51661 agcaatccac gtattctgat ttttgatgat tcgacctcag ccttggatgc caaatcagag
    51721 cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct
    51781 caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg
    51841 attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat
    51901 gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc
    51961 ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagct attgaaaaag
    52021 tccatttttt caaaggtaat cctgtgttaa tttcagaaat tacatcactt tttgttcgtc
    52081 aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt tgcaaggtgg
    52141 atgatggcta cattgtaatg ttttccttgt tctaacttag tcttaagata ggccttaaaa
    52201 gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtacctaccg cagatgaggg
    52261 gaaccccgtt tgaccattct tcctgctaaa tcaatctgac ctgactgata aatagaagaa
    52321 tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat atttcgaatc
    52381 tcggctaaaa tgaccgcccc taaacgattc tcaatcccag taaccgtcgt gatgaccgag
    52441 ttgaactcag ccatcaagtc attgacacat tttttcgcct tgtcaatgag cctcttgtaa
    52501 tgtttgatgt tttcattaca agagataaaa cgtttatgcg ttatcaaact cattaccaat
    52561 tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg aggaaatgaa
    52621 ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag ctaactgcgc
    52681 taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc attattttaa
    52741 ggtctacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga cttttgccca
    52801 agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt tagttcaagc
    52861 ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca tggtcaatct
    52921 tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc tcatgacgcg
    52981 cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc ttgctcagtt
    53041 gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga
    53101 tttggataat atcctccaag cctttaacga aagcttgatt caggtcatga gcaatattgt
    53161 tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac
    53221 cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa tggcacgtaa
    53281 atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg atgagagcat
    53341 ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg caggatttct
    53401 tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct caggaattct
    53461 tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct ttgctggttc
    53521 ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt tgattgttat
    53581 gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag cgagttgggg
    53641 aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg atgcagagga
    53701 ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg ttgaaatcag
    53761 tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca gcatttctgc
    53821 ccctaaaggc cagatgacag cagttgttgg gcctacaggt tcaggaaaaa cgactattat
    53881 gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg atggtaaaga
    53941 cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat tgcaagattc
    54001 ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag atgctaatca
    54061 ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg aaagtttgcc
    54121 tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag ggcagaagca
    54181 attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc tcgatgaagc
    54241 aacttcaaac gtagatacgg tgacggaaag caagattcag catgccatgg aggtggttgt
    54301 agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca atgcagatca
    54361 gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg aacttttgaa
    54421 gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat aagaaagaag
    54481 ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa
    54541 aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag tattcgaaag
    54601 gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc ccgtagacgc
    54661 agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca ttcgtcaagt
    54721 cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg attatgtgga
    54781 aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt tttatggaga
    54841 gaaaaagacc gtcgaaagcg atgattacaa tctggtccgt gacgaatttg aattggcact
    54901 cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg gtgtccaact
    54961 tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact
    55021 acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg ctaagctatt
    55081 tgggaaagaa agtcaggtca actcagtcca tcgtcaaagc attaaagatt tggcacctaa
    55141 tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg agtctatcga
    55201 cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg aagaagatgg
    55261 caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac atctggtcgt
    55321 tctttctttt attttttcaa aatttttaga atgtggcatt ttacgcaaac gtttgaattc
    55381 tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga
    55441 tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat tattcaaaag
    55501 ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa gtaacagcag
    55561 cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga tggttggacc
    55621 ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct gagcaaatca
    55681 agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag
    55741 cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa gaacgcaaag
    55801 ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct gacttggtag
    55861 agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt acaacaactg
    55921 aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac ggtcaagaag
    55981 aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt aaggttgaag
    56041 cagacgctaa cggttgggga acatttgttg ttccagatga tatcggtgga cgcttctcag
    56101 tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc aaagctctta
    56161 tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct gaaaacgaag
    56221 cttaccaata cgcagtcgtt cgtaacatcc tttatcgtaa aggctatgca actgagatct
    56281 tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa ttggctggtg
    56341 aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc tcaactgact
    56401 tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa acagttgtcc
    56461 gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac cttgacggac
    56521 ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact gacggtgttc
    56581 ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca gagcaagacg
    56641 ctttcactct tggttacact atctacttct tcgaattggc aattgccctt tcaggttact
    56701 tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt aacatgtttg
    56761 cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca cgtctataat
    56821 agaagaaaag agtggtttgc ccactctttt tactctcttt atccatagaa attggactca
    56881 gccaagactt gtgatataat atagaaagca aaaaggcaga cgcctagata ataggagaaa
    56941 ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta ctacacatcg
    57001 gaaatgcccg tacagcattg tttaactact tgtatgcgcg ccatcatggt ggaacatttc
    57061 tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac
    57121 ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca catgagaatt
    57181 atcgccagtc tgagcgtttg gacttgtatc aaaaatacat tgaccaacta ttagctgaag
    57241 gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgt gaacgtcaag
    57301 aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt gaagaagaaa
    57361 aagcggctta tatcgcagaa cgtgaagcag ctggtatcat accaacagtt cgtttggctg
    57421 tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggtgatatc gaatttgaag
    57481 gtggcaatat cggcggtgac tgggttatcc aaaagaaaga cggttaccca acttacaact
    57541 ttgccgttgt tatcgatgac cacgatatgc aaatctctca tgttatccgt ggagatgacc
    57601 atattgctaa tacaccaaaa cagcttatgg tctatgaagc tcttggttgg gaagctccag
    57661 agtttggtca catgaccttg attatcaact ctgagactgg taagaagtta tctaaacgtg
    57721 atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt ccagaagcag
    57781 tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag attttctctc
    57841 gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca gcagcctttg
    57901 atcagaaaaa attagactgg atgagcaatg attatatcaa gaatgcagac cttgaaacca
    57961 tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac aaggctgaaa
    58021 aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc ccattgacag
    58081 atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc atgacgggtg
    58141 aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg acagatgatg
    58201 aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta
    58261 aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg catgggccag
    58321 aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca
    58381 ttctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga aaagatgtac
    58441 gaagaagcac agaaactata caatccacat gaagtatcag actttgttta tgccaatcat
    58501 gttgtagctg cagtagaagc aggagatgga caaatattta caggattctg tatggaggga
    58561 acctgtggtg ttttccatct ctgcgcagaa cgggcgaccc tcttcaatat gtaccaattt
    58621 tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc ttatggtgga
    58681 agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa tgctgaaaat
    58741 aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt cgcagaacta
    58801 atcccttatt ggtggggaga agaacgtgct tctaagttta atgagtgata gaagagtcag
    58861 tataattctg gctcttttta ctataagttg aaaaaataaa aaaagtttaa aaaagtagtt
    58921 gacaaagttt gaaaaggctg tataatagta agagttgaaa ataacaactc aggtccgttg
    58981 gtcaaggggt taagacaccg ccttttcacg gcggtaacac gggttcgaat cccgtacgga
    59041 ctatggtatg ttgcgtcagg accacttgat gaaaaaaagt ttaaaaaagc
//
LOCUS       DAVLTG010000008        49658 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLTG010000008 DAVLTG010000000
VERSION     DAVLTG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.008"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            217..423
                     /locus_tag="VYN12_000504"
     CDS             217..423
                     /locus_tag="VYN12_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414939.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
     gene            420..614
                     /locus_tag="VYN12_000505"
     CDS             420..614
                     /locus_tag="VYN12_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414940.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            601..1485
                     /locus_tag="VYN12_000506"
     CDS             601..1485
                     /locus_tag="VYN12_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414941.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENIIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            1487..2224
                     /locus_tag="VYN12_000507"
     CDS             1487..2224
                     /locus_tag="VYN12_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1414942.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            2224..3321
                     /locus_tag="VYN12_000508"
     CDS             2224..3321
                     /locus_tag="VYN12_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1414943.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILTVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            3323..3922
                     /locus_tag="VYN12_000509"
     CDS             3323..3922
                     /locus_tag="VYN12_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1414944.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            4347..5357
                     /gene="ccpA"
                     /locus_tag="VYN12_000510"
     CDS             4347..5357
                     /gene="ccpA"
                     /locus_tag="VYN12_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1414945.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(5563..6525)
                     /locus_tag="VYN12_000511"
     CDS             complement(5563..6525)
                     /locus_tag="VYN12_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1414946.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            6591..7979
                     /locus_tag="VYN12_000512"
     CDS             6591..7979
                     /locus_tag="VYN12_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1414947.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(8014..8466)
                     /locus_tag="VYN12_000513"
     CDS             complement(8014..8466)
                     /locus_tag="VYN12_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1414948.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            8629..8922
                     /locus_tag="VYN12_000514"
     CDS             8629..8922
                     /locus_tag="VYN12_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414949.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVVKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9078..10292
                     /locus_tag="VYN12_000515"
     CDS             9078..10292
                     /locus_tag="VYN12_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1414950.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            10437..10571
                     /gene="rpmH"
                     /locus_tag="VYN12_000516"
     CDS             10437..10571
                     /gene="rpmH"
                     /locus_tag="VYN12_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1414951.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            10834..11499
                     /locus_tag="VYN12_000517"
     CDS             10834..11499
                     /locus_tag="VYN12_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1414952.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLETTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKNKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRLVAPNAA
                     PKTTSAPQATAGTMQNVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            11804..12577
                     /locus_tag="VYN12_000518"
     CDS             11804..12577
                     /locus_tag="VYN12_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1414953.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMIISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            12577..13137
                     /gene="rnmV"
                     /locus_tag="VYN12_000519"
     CDS             12577..13137
                     /gene="rnmV"
                     /locus_tag="VYN12_000519"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1414954.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            13209..14108
                     /locus_tag="VYN12_000520"
     CDS             13209..14108
                     /locus_tag="VYN12_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1414955.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            14428..14724
                     /locus_tag="VYN12_000521"
     CDS             14428..14724
                     /locus_tag="VYN12_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1414956.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            14801..16831
                     /locus_tag="VYN12_000522"
     CDS             14801..16831
                     /locus_tag="VYN12_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1414957.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDCLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            16833..17474
                     /locus_tag="VYN12_000523"
     CDS             16833..17474
                     /locus_tag="VYN12_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414958.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            17467..17760
                     /locus_tag="VYN12_000524"
     CDS             17467..17760
                     /locus_tag="VYN12_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414959.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            18011..18883
                     /gene="rsmA"
                     /locus_tag="VYN12_000525"
     CDS             18011..18883
                     /gene="rsmA"
                     /locus_tag="VYN12_000525"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1414960.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            18885..19763
                     /gene="rsgA"
                     /locus_tag="VYN12_000526"
     CDS             18885..19763
                     /gene="rsgA"
                     /locus_tag="VYN12_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1414961.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            19774..20430
                     /locus_tag="VYN12_000527"
     CDS             19774..20430
                     /locus_tag="VYN12_000527"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1414962.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            20393..21055
                     /locus_tag="VYN12_000528"
     CDS             20393..21055
                     /locus_tag="VYN12_000528"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1414963.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            21057..22313
                     /locus_tag="VYN12_000529"
     CDS             21057..22313
                     /locus_tag="VYN12_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1414964.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            22303..23244
                     /locus_tag="VYN12_000530"
     CDS             22303..23244
                     /locus_tag="VYN12_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1414965.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            23511..24338
                     /gene="purR"
                     /locus_tag="VYN12_000531"
     CDS             23511..24338
                     /gene="purR"
                     /locus_tag="VYN12_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1414966.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            24405..25655
                     /locus_tag="VYN12_000532"
     CDS             24405..25655
                     /locus_tag="VYN12_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1414967.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            25781..26575
                     /gene="pflA"
                     /locus_tag="VYN12_000533"
     CDS             25781..26575
                     /gene="pflA"
                     /locus_tag="VYN12_000533"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1414968.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(26650..27576)
                     /gene="yidC"
                     /locus_tag="VYN12_000534"
     CDS             complement(26650..27576)
                     /gene="yidC"
                     /locus_tag="VYN12_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1414969.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(27654..27932)
                     /locus_tag="VYN12_000535"
     CDS             complement(27654..27932)
                     /locus_tag="VYN12_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1414970.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            27966..28706
                     /locus_tag="VYN12_000536"
     CDS             27966..28706
                     /locus_tag="VYN12_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1414971.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28762..29445
                     /locus_tag="VYN12_000537"
     CDS             28762..29445
                     /locus_tag="VYN12_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1414972.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            29557..30549
                     /locus_tag="VYN12_000538"
     CDS             29557..30549
                     /locus_tag="VYN12_000538"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1414973.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            30614..31153
                     /gene="rsmD"
                     /locus_tag="VYN12_000539"
     CDS             30614..31153
                     /gene="rsmD"
                     /locus_tag="VYN12_000539"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1414974.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            31143..31631
                     /gene="coaD"
                     /locus_tag="VYN12_000540"
     CDS             31143..31631
                     /gene="coaD"
                     /locus_tag="VYN12_000540"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1414975.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            31615..32652
                     /locus_tag="VYN12_000541"
     CDS             31615..32652
                     /locus_tag="VYN12_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1414976.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            32710..32940
                     /locus_tag="VYN12_000542"
     CDS             32710..32940
                     /locus_tag="VYN12_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1414977.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            32964..34247
                     /gene="murA"
                     /locus_tag="VYN12_000543"
     CDS             32964..34247
                     /gene="murA"
                     /locus_tag="VYN12_000543"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1414978.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            34240..34428
                     /locus_tag="VYN12_000544"
     CDS             34240..34428
                     /locus_tag="VYN12_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1414979.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            34467..35291
                     /gene="endA"
                     /locus_tag="VYN12_000545"
     CDS             34467..35291
                     /gene="endA"
                     /locus_tag="VYN12_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1414980.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            35582..36913
                     /locus_tag="VYN12_000546"
     CDS             35582..36913
                     /locus_tag="VYN12_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1414981.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELISQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(37111..37181)
                     /locus_tag="VYN12_000547"
     tRNA            complement(37111..37181)
                     /locus_tag="VYN12_000547"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37147..37149),aa:Cys,seq:gca)
     gene            37597..41208
                     /gene="rpoB"
                     /locus_tag="VYN12_000548"
     CDS             37597..41208
                     /gene="rpoB"
                     /locus_tag="VYN12_000548"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1414982.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41241..44918
                     /gene="rpoC"
                     /locus_tag="VYN12_000549"
     CDS             41241..44918
                     /gene="rpoC"
                     /locus_tag="VYN12_000549"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1414983.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            45029..45442
                     /gene="ndk"
                     /locus_tag="VYN12_000550"
     CDS             45029..45442
                     /gene="ndk"
                     /locus_tag="VYN12_000550"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1414984.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(46371..47003)
                     /locus_tag="VYN12_000551"
     CDS             complement(46371..47003)
                     /locus_tag="VYN12_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1414985.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(47005..49020)
                     /locus_tag="VYN12_000552"
     CDS             complement(47005..49020)
                     /locus_tag="VYN12_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1414986.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(49470..49640)
                     /locus_tag="VYN12_000553"
     CDS             complement(49470..49640)
                     /locus_tag="VYN12_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414987.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
BASE COUNT        14555 a         9462 c        11319 g        14322 t
ORIGIN      
        1 actctttttg attttaaata agtattagtt tacattatgg tgtgaattgg gtttgatatc
       61 tcttttgagg aagttgcctt agatttttct gattgtgttt tattgtatag tgtatcttgc
      121 ttgttttgaa cagaattttt atgacatttg tcatattttc tagtgacaga agcttctgcc
      181 tcctctgatt ttaaaagact ataattgtag tatgaaatgg gggaagaaga gatgagaaat
      241 aaaatgatta ttgcaatgag tttagtagta gcaggagtta tgacctatct catgttttcg
      301 ggattggatg aggatttcta ccattttcct tggaaggtct ttgctggctt tggaatcatg
      361 tcttggcttg ttagagaagg tttgaaatta gtcagagatg tgaaaaagga gtttgaggaa
      421 tgaagagagg gatcatctat ttctttatcg gcctgtcact cttggtatgg ttagtggaaa
      481 tgtttactga ttggtttgat caagccttgc ttcgccaatt catttgtggt gctttggggt
      541 ttggatttat gattttcgtc gttttcccta tgggaatgga gtggttgaaa ggagagtctc
      601 atgactgtgg ttaaagttga aaaattgagt aagaaaataa aagacaagga aattttgcgg
      661 aacatctcct ttgaaatcaa cgatggtgaa tgtgttgcct taattggtcc aaatggtgcc
      721 ggaaagacaa cactcttaga ttgtttgctt ggagataaac tggtcacaag cggtcaagta
      781 tctattcaag gtttaccagt gacgagttct aagttagact atactagggc ttacctccct
      841 caagaaaata taatcgttca gaaattaaaa gttaaagagt tgattgcttt ctttcaacgt
      901 atctatccaa atcctttgag caatcaggaa attgatcaac tattgcagtt tgtcaagcaa
      961 caaaaagaac agttggcaga aaaattatca ggcggtcaaa agcgtctctt ttctttcatc
     1021 ttgaccttaa ttgggcgacc aaagattgtt tttttagatg agcctactgc gtccatggat
     1081 acctcaactc gtcaacgttt ttgggaaatt gtccaggagt taaaagcgca aggagtcacc
     1141 attctctatt cgtcccatta tattgaggaa gtggaacaca ctgcagaccg cattttgctc
     1201 ttaaataagg gagagttgat tcgagatacg acgcctctag ctatgcgtag cgaggaaata
     1261 gaaaagcact ttatccttcc tatagcttac aaggaagtcg tagagcagtc aaatttggtt
     1321 gaaaactgga ccctaaagca agattcttta caagtagtca ctcgagaagc agatgctttc
     1381 tgggaactat tagcccaagc aggatgtagg atgcaagaaa tcgaagttaa taatcgtagt
     1441 ttgttgaata caatctttga agagacgcag aagggagata actaagatga aacgatggat
     1501 agcacttagt aagatagaat ttttattgac caaacgacaa ttaatctatt atctattgtc
     1561 ggtagggatg ccgacggctt tctatttatt tttttctggt atctatcagg acacaccagg
     1621 tgaactcgcg aattttatgc gtgattatct tatctccatg actgcatttt ccatgatgtc
     1681 aacagctatc ttctcattcc cagttgtttt acataccgac aagatcaaca actggcagaa
     1741 aacattgcgt catagccctg taaatatggt agaatattat ctatcaaaga taacaagtat
     1801 gctggttgat tatttggttt caatcttggt ggttttctca gttgggcatt ttgtaagagg
     1861 tgtggacatg tctcttggaa attggattgg ggctgcactt ttgctgatag taggaagtat
     1921 tgccttcgta gcgcttggtt tgaccttgac tctcttacca actagtcagt tgatgtctgt
     1981 cgtgggcaat cttctttatc tagggttggc tgttttaggt ggactctgga tgcctatctc
     2041 tttatttcca gactggatgc aagtagtagg taagtgtctc ccgacctatc agttgatgga
     2101 gttgctcaag accttcttaa atgagggtgg catcaatcta tcagccacag tttatttact
     2161 tgttttttca gtagttttgt ttggtttgac catttacctt caaggtcata aggagaatgc
     2221 ttaatgcttg aaagactgaa aagcatacat tatatgtttt ggatcagttt aatttttatg
     2281 gttttcccca tcctaactgt agtgactggg tggctttctg cctggcattt attgattgat
     2341 attctatttg tagtggcgta tttgggtgtt ttaacaacta agagccagcg tctatcttgg
     2401 ctatattggg gcatcctgct gacttatgta gttgggaata ctgcctttgt ggctgttaat
     2461 tatatctggt ttttcttttt cctatccaat ctcttaagct atcatttcag cgtaggtggt
     2521 ttaaagtctt tacatgtctg gacttttctt cttgctcaag tccttgttgt gggtcaactg
     2581 ttgatttttc agagaatcga agttgagttt ctattctatc tacttgtaat tcttgctttt
     2641 gtcgatttaa tgacttttgg cttggttcgg attcgaattg tggaggattt gaaagaagca
     2701 caggctaagc aaaatgccca gataaatcta ttgcttgctg aaaatgaacg caatcgtatc
     2761 ggtcaagatt tgcatgatag tctggggcat acctttgcta tgcttagtgt taaaactgat
     2821 ctagccttgc agttatttca gatggaggct tatccacagg tggaaaagga attaaaagaa
     2881 attcaccaga tcagcaagga ttccatgaat gaagttcgaa ctatcgtgga aaatcttaag
     2941 tctagaactt tgacatccga actagagact gtgaaaaaga tgttagaaat tgctggaatt
     3001 gaggtggaaa cggataacca actagatact gctagcctta ctcaagaatt ggagtcaatg
     3061 gcttctatga ttttgcttga gttggtgacc aatatcatca aacatgccaa agcgtctaaa
     3121 gcttacttaa aattagaacg gacagagaag gaactcattt taacagtaag tgatgatggc
     3181 tgcggctttg cttttctaaa aggagatgag ctccatacag tccgagatcg tgtttttcca
     3241 ttttcaggag aagtaagtgt aatcagtcag aaacatccaa cggaagtgca agttcgacta
     3301 ccttataagg agagaaacta agatgaaagt attagtcgca gaagatcaaa gtatgttgcg
     3361 agatgccatg tgtcaattgc tcacgcttca accagatgtg gagtctgtcc ttcaagccaa
     3421 gaatgggcaa gaagcaatcc aactattaga aaaggagtct gtagatatcg ccatccttga
     3481 cgtagaaatg cctgttaaga caggtcttga agtcttggag tggatacgat cagaaaagct
     3541 tgaaacaaag gtggttgtgg tgacgacctt caagcgtgct gggtattttg aacgtgcggt
     3601 caaggctgga gtggatgctt atgtattaaa ggaacgaagc attgcagacc tcatgcaaac
     3661 cttgcacacc gtcctcgaag gacgcaagga gtattcgcct gaattgatgg aaatggtgat
     3721 gacccgtccc aatccgttga cagaacaaga gattgctgtc ttaaagggaa tcgcccgggg
     3781 cttatccaac caagaaatcg cagatcagct ttacctctca aacggaacta ttcgaaacta
     3841 tgtcaccaat attctttcaa aactggatgc tggtaatcga acagaggcag ctaatatcgc
     3901 aaaagaatct ggttggttat gatgatataa tattttcatg aagactatgt gctaaaattg
     3961 acggtagtga atggaacaat acctatagta gattgaaact agaatagtac acctctactt
     4021 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttatttca
     4081 ttttactata actttaggag ggcttagttt cctccttttt gtttagtcta aggtggtagc
     4141 aaggagctaa acctaggttt tctatgaaat tttttcaatc aatcttcaaa aaacacttga
     4201 aagtgtttac aattagtgat agaatggaat aagtagaaat atgaaaacga aattttcaca
     4261 tcttcacttt tgtaagtaga tatagagctt caatcagtac ctctacttgt aaaagaatgt
     4321 gtgagataga aaggacagga aaaggaatga atgcagatga tacagtaacc atttatgatg
     4381 tcgctcgtga agcaggtgtt tccatggcga cggtcagccg tgtggtcaat ggcaataaaa
     4441 atgtaaaaga gaatacccgt aaaaaagtgc tagaggtaat tgatcgtttg gattatcgtc
     4501 caaatgcagt tgcgcgtggt cttgcaagta aaaagacaac cactgtcggt gtcgtgattc
     4561 caaatattac caatggttat ttttcgagtt tggctaaggg gattgatgat attgcagaaa
     4621 tgtacaagta caatattgtc ctagctaata gcgatgaaga taacgagaaa gaagtttctg
     4681 ttgtcaatac cctcttttca aagcaggtag atggcattat ctatatgggg tatcacttga
     4741 cagataaaat tcgctcagaa ttttcgcgtt cacgtactcc gattgttctc gcaggaactg
     4801 tcgatgttga gcaccagttg ccaagtgtca atattgacta taagcaagca acaattgatg
     4861 cagtgagtta ccttgctaaa gaaaatgagc gtattgcttt cgttagcggt ccgctagtgg
     4921 atgacatcaa tggtaaggtt cgtttagttg gctacaagga aaccttgaaa aaagcaggaa
     4981 tcacttatag tgagggtttg gtatttgaat ctaaatatag ctatgatgat ggttacgcct
     5041 tagcagagcg tttgatttca tcaaatgcaa ctgcagcagt tgtgacaggt gatgagttgg
     5101 cagcaggagt cttgaacggt ttggctgata agggtgtttc tgtgccagaa gattttgaaa
     5161 ttattactag tgatgattca caaatctcac gctttacccg tccaaacttg acaacgattg
     5221 cccaacctct ttatgacctt ggtgccatta gtatgcgtat gttgaccaag attatgcata
     5281 aggaagagtt ggaagaacgt gaagttctct tacctcatgg tttgacagaa cgtagctcaa
     5341 cacgaaaacg taaatagaaa aaatcaggga atcgagaaga tttcctgatt ttgtgctctt
     5401 aaacaagaga tgttgactta atgaatacca tagagcggac taggcggctg gttaaaggct
     5461 gcgcaacaca ctgttttgag gttgtggatg aaactgacga agtcagtaac catacatacg
     5521 gtaaggcgac gtgacgtggt ttgcagagat tttcgaagag tattagcctt ccatatagtc
     5581 tttcaaagcc tgtcctgtta gtccggcatt gagggcgatg aggagtttca agcgagcttt
     5641 ttgggcattg agttctttaa caaagaaaac gcctgctttt tgcaactgta cgcccccacc
     5701 ctggtaggca taaacaggct cggcaatacc gttaaagcat cgtgatacca gagcgactgg
     5761 gattcctttt tgcagaaggc tttctaattt ttgagccgtt tctttgggaa tattaccagc
     5821 tccgaaggct tggataatca aaccgtccaa gtgttctaaa tccagcatat caatcagctc
     5881 atctgtcata ccagcataag ccgagatgat agggactaaa ccttgtatgt gatcaaggtc
     5941 aaagcgaaca cgaggttcag ctgttttgaa gtagaggatt tcctgtttca tgatgagacc
     6001 gagggggcca tgtgttggag tctggaaggt gctgacatta gtcgtatgtg ttttggtgac
     6061 atacttggca gcgtggattt catcgttcat aacgaccaaa actcctttgt cagcagccct
     6121 gtcatcgctg gccactcgta aagcacttag gtaattataa acaccatcac taccgagctc
     6181 attggagcta cgcatggctc ctgttagaac gataggcata tggggaactt ccatggtatc
     6241 aaggaaatag gctgtttcct ctaaagtatc ggttccgtgt gtgatcacca ctccatcgta
     6301 gttatctgct tcctctttaa ttttctggta gaggaccagc atatgtttgg gtttgatatg
     6361 gggacttgga aggttaaaaa agtccaaggc gtggacttgg attccttcaa gtgggttgga
     6421 cacatggttc atgggattat ctgaactcgt cacaacagcg ccagaagcat cggcctgcat
     6481 ggaaatagtt ccacccgtat gtaaaacaag gattttctta ggcatgattt actcactctt
     6541 tctgaaatgt ggtataatca ttgtatcaca aaaggggaga ttgggatagg atggaagtca
     6601 aagctgtttt ttttgatatc gatggaacct tggtcaacaa tcgcaagagt gttttgaaat
     6661 ccactaagga tgcgattaag attgtcaaag aacaaggggt actagttggc gtagcgacag
     6721 ggcgaggacc tttttttgtt aaggaattga tggacgattt ggatctggat tttgcggtaa
     6781 cctataatgg ccagtatatc tttagtaaag acagagtctt gttcacgagc cctatttcca
     6841 agttacattt gcgccatcta attagctatg ctaaaaaaga gggcacggag attgctctag
     6901 ggaccaagga tgccatgttg ggttctaaaa tcatgtcctt tggtctgggt tctttttccc
     6961 aacgaattag tcgcttcgtt ccctctgttt taactcggac ggtgagtcag tcttttaatc
     7021 gcatggtcag caaggttgtt ccccaaaagg aagaggacct gcttcacctg atgaatcagc
     7081 ctatctacca agttttgatg ctgatgacac cagaagaatc tgagaaggcg gcagctgatt
     7141 ttgaagactt gaaattgaca cgtagcaatc cttttgcatc ggatgtcatc aatcagggaa
     7201 attctaaatt agaaggcatt cgccgagttg ggaaagaata tggctttgac ctcaaccaag
     7261 tcatggcttt tggtgactca gataatgacc ttgaaatgct ggctggcgtc ggtatgtcgg
     7321 tcgctatggg aaatggtagt agcagtgtca aggaagctgc caagcacatt accactagca
     7381 atcaacaaga tgggatccac aaggccttgg aacattttgg tgttttgtct tcagaaaaag
     7441 tttttgtcag ccgtgactat catttcaata aggtcaagac cttccaccac atgatggatg
     7501 aacgaaccca agaagaacct cgagcttggg atttagaggg tgcaacccat agggctggtt
     7561 ttaaaataga agaattggtg gagtttgttc gatcagccag tccttctgaa gaagattttg
     7621 gtcaagctgt atcgcaactt catcaggccc ttgataaggc agcaggtaaa gtagccaaga
     7681 agacacctgc tcagcaagat ttgatagggc aagtggatgc cttgattgac acgctttact
     7741 tcacctacgg cagttttgtc ttgatggggg tggacccaga acgtattttt gatattgtcc
     7801 atcaggccaa tatggggaaa atttttccag atggcaaggc tcattttgat ccagtgaccc
     7861 ataaaatctt aaaaccagat aattgggaag aaaaatatgc tccagaacct gctattaaaa
     7921 aggaactgca gcgccagctc aaggcttacg aacgccataa agagagaaat aaatcgtaaa
     7981 caaaaaggag ctaggggctc cttttctttg tgattataag gttttttctt gttctctcac
     8041 aaccagcaaa tcgaccttag catggcggag tatgtattca gatgaagagc cgactaagag
     8101 gcgttcaaag gcgttgagac cagttgcgcc aacgaggatg aggtccactt cctcggcatc
     8161 tggaatagta cgtgctagca gggtctttgg atttcccatt tcaatgacga tatgaacatc
     8221 tgctacccca gcatctttag cacgtttttc gtactctttc atcagacttt cagcgtcgac
     8281 ttggagttct tcgtaaactt cagcatcaaa ggtggatacg ctttggagag cgcgtgtgtc
     8341 aatgacatgt gcgatggtga gtttagcgtc gtttcgtaga gcagaatgaa ctcccttgac
     8401 aaaagccaag tccgcttcct tagaaccatc gattgcgacc atgatatttt ggtaacgttg
     8461 tgccataatg aaacctcctg aaattttctt actataattg taaacctttt cactatagaa
     8521 gtaaagcaaa aaaaagtatt tttcaaaaga atattagggt ttaaactcta tataaatata
     8581 tgataaaata aaagaaagga tagcaggaaa gaagtgaagg aagggagaat gatgaaaaac
     8641 tcttttcaaa aatcaaattt cctttattat ggaattatcc tagtttcagt cttggtagaa
     8701 gtgatcatga tctgtcaatt agagagtctg gtaccgcttc tttatccaag ttttattgga
     8761 tttttagtct ttcatgtact ctaccatcta atcttatttc tagttgtaaa acgaagtggg
     8821 cgttgggatt acttgatgat atgggggctt ttcctcatgt ttaatcttct ttatgactcc
     8881 tttctaggct tgctttttct aggtttatct tttggtatgt gatgtgtctt tgcaaaatac
     8941 ctgctatctc tacgttctta acctcgcctt tagcaaggtt tttcttctat acgaaactag
     9001 taacacattt cagtaaactt gtcgcattct ctttctagtg gtataatgtt actatcctga
     9061 tgaattgagg aaacaagatg aaagaatata acaagtctag taagttagag catgttgctt
     9121 atgatatccg tggtcctgta ttggaagaag ccatgcggat gcgagcgaat ggagaaaaga
     9181 ttttacgtct gaatacagga aatccagcag aatttggctt tacagcgcca gacgaggtca
     9241 ttcatgactt gattatgaat gcgcgtgata gtgaaggcta ttctgactcc aaagggattt
     9301 tctcagcccg taaggccatc atgcagtatt gccagctgaa gaaattccca aacgtagata
     9361 ttgatgatat ttaccttgga aatggtgtca gtgagttgat tgtcatgtcc atgcaggggc
     9421 ttttggacaa tggggatgag gtcttagtgc caatgccaga ctatcctcta tggacggcgg
     9481 ctgtcagcct agctggagga aatgccgttc actatatctg tgatgaagct gttgaatggt
     9541 acccagatat tgacgatatc aagtcaaaaa tcacttccaa taccaaggca atcgtcctta
     9601 tcaatccaaa taacccaact ggagcccttt atcctaagga actcttgctg gagattattg
     9661 agattgcccg tcaaaacgat ttgattatct ttgcggatga aatctatgac cgcatggtaa
     9721 tggacggaca tgtgcatacg cctgtggcga gcttggcacc agatgtcttc tgtgtcagca
     9781 tgaatggtct gtcaaaatcc caccgcatag caggttttcg tgtgggttgg atggtcttgt
     9841 ctggccctaa gactcatgtt aagggctata tcgaagggct caatatgctg tccaatatgc
     9901 gcctttgctc taacgttttg gcccaacaag tcgtacaaac ttccttgggg gggcaccaat
     9961 cagtcgatga attgcttctt cctggtggac gaatctacga gcaaagaaat ttcatctata
    10021 atgccattca agatattcca ggtttgtctg ccgttaaacc caaggcgggg ctctatatct
    10081 tcccaaaaat cgaccgcaat atgtaccgta tcgatgatga tgagcagttt gtccttgatt
    10141 tcttgaagca ggaaaaggtt ctcttggttc atggtcgagg ctttaactgg caggagccag
    10201 accacttccg tatcgtttac cttcctcgtg ttgatgagtt agcccaaatc caagaaaaga
    10261 tgactcgttt cttgaaacag tatcgtagat agggcttgca ttcgaaaaag ctggaaacat
    10321 ttgcctagag ctattgacaa aagtgaaaga atcagataga atagtaaagt atgtttagta
    10381 actgatcact ttatagccgg ctaaacgaat acaaaatcta tgaggaggta ttcatcgtga
    10441 aacgtactta tcaaccaagt aaacttcgtc gtgcgcgcaa acacggattc cgtaaccgta
    10501 tgtcaactaa aaatggtcgt cgcgtattgg cagctcgtcg tcgtaaagga cgcaaagttt
    10561 tggctgcata atccaaacga attctatcaa aaatcagtag gaactcgagt ctactgattt
    10621 ttatttttgt aaaaaagttc agtagatgca aatggattcg gaagcgatgt tacagtagat
    10681 tgaaactaga atagtacacc tctgtttcta aaacattgtt agaaatcgat ttgactgtcc
    10741 tgatcgattt gtcctgttat tattttattt tactataaag ttgaagtagg tggagatggt
    10801 acagcaacaa tcacattccc agatggttca gtagtgacga ttctaggaaa agatacagtt
    10861 caacaatctg cgaaaggtga atctgtaact caagaagcta caccagagta taagctagaa
    10921 actacaccag gtggagataa gggaggcaat actggaagct cagatgctaa tgcgaatgaa
    10981 ggcggtggta gccaggcggg tggatcagct cacacaggtt cacaaaactc agctcaatca
    11041 caagcttcta agcaattagc tactgaaaaa gaatcagcta aaaatgccat tgaaaaagca
    11101 gccaagaaca agcaggatga aatcaaaggc gcaccgcttt ctgataaaga aaaagcagaa
    11161 cttttagcaa gagtggaagc agaaaaacaa gcagctctca aagagattga aaatgcgaaa
    11221 actatggaag atgtgaagga agcagaaacg attggagtgc aagccattgc catggttaca
    11281 gttcctaaga gactagtggc tcctaatgct gctcctaaga caacaagtgc accgcaagca
    11341 actgcaggaa caatgcaaaa tgttacctac cagtcacctg ctggcaaaca attacctaac
    11401 acaggttcag catcaagtgc agcacttgct agtcttggtc tagtggtggc aacaagtggt
    11461 tttgctttgc taggaagaaa gactagacgt agaaaataga acagctagaa aattctattc
    11521 tctacttaaa gttagattat aagggggatt ttgagaagtc atcaatccta gtgatgggtg
    11581 agaaaagtga gaacccaaga taatcacata ctttagctga ataggaatat tctatcaatg
    11641 tagccaatct cttctgtctc taactgtgga ataggagata ggcaatatcg gatagaaaag
    11701 atagcagaat agctctctat tgaagagagg aggggaaacc gaaaaattag gtgcccctcc
    11761 tcttttttgg tataatagaa gatagaaaac gaggttagaa gagatgattt ttgatacaca
    11821 tacacacttg aatgtagaag aatttgcagg tcgtgaggca gaagaaattg ccttggctgc
    11881 tgagatgggt gtgatacaga tgaatattgt tggttttgat aaaccgacga ttgagcgtgc
    11941 cttggagttg gtagatgagt atgagcagct ctatgcgact attggttggc atcctacaga
    12001 agctggtact tatacagagg aagttgaggc ttacttgttg gataagttaa aacatcccaa
    12061 ggttgtggct ttaggtgaaa ttggcttaga ctaccattgg atgacagcgc ccaaagaggt
    12121 gcaggagcag gtttttcgcc gtcagattca gctatctaag gacttggatt tgccttttgt
    12181 tgtccatacc cgtgatgcgc tggaagatac ctatgagatt atcaagagtg agggcgttgg
    12241 tcctcgtggt ggtatcatgc attcattttc agggacgctt gagtgggcag agaagtttgt
    12301 ggatcttggt atgatcattt ccttctcagg agtggtgact ttcaagaagg caactgacct
    12361 ccaagaagca gctaaagagt tacctttgga caagatgttg gtggaaacag atgcgcctta
    12421 cttagcacct gtacccaagc gtggtcgtga aaataaaaca gcctatactc gctatgtggt
    12481 cgactttatc gctgacttgc gtggtatgac gacagaagag ctggcggtag caacgactgc
    12541 aaatgcagaa cgaatttttg gattggacag caagtaatga aagagaaaat ttctcaagtt
    12601 atcgtggttg aaggtcgcta tgatacggtc aatctcaagc gttatttcga tgtggagacc
    12661 tatgagacac gaggttctgc catcaatgat caggatatag agcgaattca gcgtctacac
    12721 caacgtcatg gagtcattgt ctttacagac ccagatttta atggggaacg gattcggcgc
    12781 atgatcatga cggtcattcc aacagttcag catgcctttc tcaagcgaga tgaagctgtt
    12841 cccaagtcca agaccaaggg gcgttctctg ggaattgagc atgccagcta tgaagacctg
    12901 aaaacggctc tagctcaggt gacagaacaa tttgaacatg agagtcagtt tgacattagt
    12961 cgtagcgatt tgattcgcct tggttttcta gcaggggcag acagccgtaa gcgtagagaa
    13021 tatctcggag agactctccg aatcggctat tccaacggca agcaactcct caaacgccta
    13081 gagttgtttg gggttacttt ggcagaagtg gaagaagcta tgaaatctta tgagtaggaa
    13141 agatgtagcc gttacaattt tttaagtttc acagtatttt tcgaagcagg tagaagagga
    13201 ggcgtctgat gttaattggt caaaaaatta aagagattcg gatagaaaaa ggaattagtc
    13261 gtccagattt ttgtggagat gagcaagaac tgacagttcg tcaactgtcg cgaattgaaa
    13321 gtggagcttc gcaaccgagt ttgcccaagt tagactatat tgctcgccgg ctaggagttc
    13381 cagtttatag ccttatgccg gatttttcag ctcttcctcc tgcttattta gaattgaaat
    13441 accagatttt acgtgaacca atctatggta aagaagagga gtacgataag aaggaagcgt
    13501 gtttggaaga gatttataaa acatactttg ataatcttcc taaagaagaa caattagcat
    13561 gtgaagtatt gcaggcgtgt ttggatactt ctagaactag aaggcctgaa tatgcagagt
    13621 taatacttga ggaacatatg tctcagatca tagaaaaaga agtttattca acaaatgata
    13681 tgttgttgat tcgtttgttt ttttatcaaa tgctcattag aaaagatctt gccaaattta
    13741 taaatcaaat cgaaaagcta atgctctttc ttttggaaca gaaaaaggta actaaattag
    13801 aaaacttctt tataattaga gatactctta tttcaggaat gtgttgtctt gaaaaggtag
    13861 gagtaactga ttgttttaat gattatctat cgtgtttaca agaaattatg gataaaactc
    13921 aagattatca aaagaaacct cttgtattta tgtttttgtg gaagcaagca ttaagagaag
    13981 aaagagattt tagtttagct gaatcatttt atcagtcttc taaaacattt gcgaagctaa
    14041 ttggagatgg atttctagta aagaaattga cagaggaatg gcaagaggat gtcaaaaaat
    14101 atttataaac atagtgaatc agtgacaaaa atgtccttgt cctcgtatca aaacagttct
    14161 aaagttcgtc tttagaactg tttttttaga tataagctaa aaataatatg aaatagttag
    14221 attttaagga cattgatgtc cttgatagtg tgataaagat ggagtataat gactataaaa
    14281 gttcatttca gggtgctatt ttgacaattt agagaaaaac aaataatttt agaatatcat
    14341 ttggtaatat aatagtatca acgttgataa tggaaagagg agcaagtaac tcaacaatct
    14401 tgtaatcaaa aatagaggag tatcaatatg aaacaaacag ttaaaaagtt agctcttgta
    14461 gcgagcattg cagcaacatt aggtggaggt gtatcagttg cctctgcagc cgttcaatac
    14521 ccagaaggtg gtgtttggac ttatggttca ggtaacggtg gtgcttactc aaactactat
    14581 cacccttcaa aataccatag ttcaacagtt gttagcagaa aaactggttc atctgacaag
    14641 ggatatgctg gtgctggagg gacttctcgt gcatggattc gtacttcttg gggagagaaa
    14701 gttgcattct actataatgt ttagaatggt atagccctat tgtttagctt tacttggtca
    14761 ccttctcact aagtgaccaa gtaacttttt ggaggaaatg atgaaacgtt tatttatttt
    14821 gatttcaatg gtattggtat cgctttatat ggtgataact tccgttgacc atcgagaaga
    14881 gattttattt ggtaactatc cttctgttga tgtgacagga atgatgataa atcaaccagt
    14941 agctagtcgc gaagaggtga cagaggcttt gagtcacttg gcggtagagc ataatagtct
    15001 catcgcccgt cgaatcgttg agccaaatga agctggagaa acactcttta cctatgccac
    15061 ttatggtgag ggagagcttc cagaaggtct gaccatttcc tccaaggaga gtgcagaaac
    15121 gagtgattta ttagggtctt acttgattgt gtcaggaagt ttggatggag tgagcttaca
    15181 gaccaccttg aaagaacttg gctatcaagg ctttgtttcg aatggagaag atccattttc
    15241 gatagtctta ctattgacgg ccacccctat ggtgctactg agtttagcta tttttctgct
    15301 gacctttatg agtctgaccc tgatttatcg gatcaaatcc cttcgtcagg cagggattcg
    15361 cttaatagct ggtgagagct tgtttggagt tgctctcaga ccagtgttag aagatgtgag
    15421 acagcttatc tgctcagtgc tggtatccag tcttttggga ttggggattc tctggtatca
    15481 aggtgccttg tttatggcaa cggtgcaact ggtcatcatt gctcttctac tttatggatt
    15541 gaccctggca gggatttcta ccttactaag tgtcgtctat ctacttggtt tacaggaaaa
    15601 tagtctggtg gatctattga aagggaaact ccctctcaaa cgtatgatga cattgatgat
    15661 ggtggggcaa ctcttagctg tattggtggt cggatcgagt gcgacagctc tcctacccca
    15721 ctaccgtgaa atgcaggaaa tggagagagc tagcaataaa tggagccagt cctcagaccg
    15781 ttaccgtcta tcctttggtt ggtctagtgc atttgccgat gaagaaggaa cgcgtaagga
    15841 taatcgtgag tggcagacat ttactgaaga acggttagcc aatacagact ctttttatat
    15901 tatgagcaat gttgacaatt tctcagatgg agcagaagtg gacctagatg gcaatcgtct
    15961 cagtgactac acaccgtcag ggaatgttat ctatgtctca ccacgctatc tgatagaaga
    16021 aaagattacc gtttcttcag agtttatgga caagatgcaa aacttgtctg agggagagtt
    16081 tgggctgatc ttgcctgaga gcttgcgaga gcagtctacc tactaccaag gattgtttac
    16141 agattacctg caaaactttt catctgaaag tgtagaagtg acgagtcaga aatactacct
    16201 cccacaggta aggctagctt ttacagaaac aggacaggaa cgtttcctct ataatgatgg
    16261 gtacaagaca acacgccagt acctaaaaga tccgattatt gtagttctaa cgccgcaagc
    16321 gactggaaca agacctgttg cagggatgtt gtggggaact acggctaata gtgccttgaa
    16381 actagatcga tatggagaca gcatcacagc tctaaaagag caaggtctgt atcacaaggt
    16441 ttcttacttg gtaaaaagcc agctattttt tgccaaggta ctaaatgaca aacgggtgga
    16501 gttttactct ctccttattg ggacgatttt gaccctgtct acggctatct tgttatttga
    16561 ttccatgaat cttctctatt ttgagcagtt cagacgggaa cttatgatta aacgtcttgc
    16621 tggtatgaca atctatgagc ttcatggcaa gtatttactg gcgcaaggag gagttctctt
    16681 gcttggccta gtcctatcta gtattttgac aagagattgt ttgattagcg ctctagttgt
    16741 agctttgttt acgcttaacg ccctcttgat tttagtaagg caggacaaaa aagaagaagc
    16801 tggtagcatg gcagtattga aaggaaaata agatgattga tattcaagga ttggaaaaga
    16861 aatttaatga ccgcgcgatt ttctctggtt tgaatctcaa gctggagaag ggcaaggttt
    16921 atgccttaat cggaaagagt ggaagcggaa agacgacgct gctgaatatc ttgggaaagc
    16981 tagaaaagat agatggtgga agggttctct atcaggggaa agatttaaaa accattccca
    17041 ctcgtgagta ttttcgagac cagatgggct atctctttca aaatttcggc ctcttagaaa
    17101 accaatcaat caaagaaaat ttggatttgg gttttgttgg tcagaaaatc tcaaaagtag
    17161 aacgtttgga aaggcaagtg ggggctttag aaaaagttaa tctagggtat ttggatttag
    17221 aacaaaaaat ctatacttta tctgggggag aggcccaacg agttgccctt gctaagacta
    17281 ttttgaaaaa tccacccttg attttggcag atgaaccaac agcagctctt gatcctgaaa
    17341 attcagagga ggttatgaat ctcttggtgg atttgaaaga tgaaaatcga attatcatca
    17401 ttgcgaccca taatccccta gtctggaata aggctgatga aatcattgat atgaggaaac
    17461 ttgctcatgt gtgaaaaaat ccgtattcgc agggtatctg attatcctag tgccagaggt
    17521 ggtttagaag atatcctcat catggaaaat atgaccaatc atctcctttt ggttcaaatc
    17581 cgagtgcatg gctatttgct tgattttgct agtattgaag ggcaaaggca aaagcattat
    17641 cgtttgaaaa atttacctca gacggttgaa ctgacagtgg atgatgtgga ggaggatgtg
    17701 gatttgaccc tacccgaaaa tcgaagttat caagaagctg atttttttga tactcaatga
    17761 aaatcaaaga gcaaactagg aagctagccg caggctgtac ttgagtacgg caaggtgaag
    17821 ctgacgtggt ttgaagagat tttcgaagag tatgaacgta tgtttcgaga gaagcactaa
    17881 gtccctcttt aaagatttcc aagactatct ttcttcatga ggaaagatag ttttttggta
    17941 tgattttcat tcccaaaata caaggggaat gtgttacaat agtagtaaca gataatagaa
    18001 aagagaatag atgagaattg cagattatag cgtgaccaag gcagtgttgg agcgtcacgg
    18061 ttttaccttt aaaaagtcct ttgggcaaaa tttcttgacg gataccaata tccttcaaaa
    18121 aattgtggat acggctgaaa ttgatgatca ggtcaatgtc atcgaaatcg ggccaggtat
    18181 tggtgccttg acagaatttt tggctgagcg tgcagcccaa gtcatggctt ttgagattga
    18241 ccaccgtttg atgccaattt tggcagatac tctgcgtgat tttgataatg tgaccgtagt
    18301 taacgaagat attctcaagg ttgatttggc gcaacatatc caaaatttta aaaatcctaa
    18361 cctgccaatc aaggtagtgg ctaatttgcc ttactacatc acgacgccta ttctcatgca
    18421 cttgattgag agtggcattc ctttttgtga gtttgtggtc atgatgcaga aagaagtagc
    18481 ggaccgcatt tcagcccagc ctaacaccaa ggcttacggt agcttgtcta tcgccgtgca
    18541 gtattacatg acagccaagg ttgcctttat cgtgcctcgt acggtctttg tgccagcgcc
    18601 aaatgtggat tcagccatct tgaaaatggt gcgtcgtcca gagccagccg tagcagtaga
    18661 agatgagaac tttttcttta aggtttccaa ggctagtttt acccatcgcc gcaagacctt
    18721 gtggaataac ttgacaggtt actttggtaa gactgaagag gtcaaggaca agctgaccaa
    18781 ggctttggac caggcaggct tgtcaccaag tgtgcgtggg gaagctctca gcttggcaga
    18841 atttgccggt ctagcagacg cacttaaagg gcaaggactc taagatgcag ggacaaatca
    18901 ttaaagcctt ggcaggtttc tactatgtgg agagtgatgg ccaggtttat caaacacgcg
    18961 cgcgtgggaa tttccgtaaa aaaggccata ccccttatgt tggggactgg gtagatttct
    19021 ctgccgagga aaattcagaa ggctatatcc tcaaaattca cgaacggaaa aacagtctgg
    19081 ttcgtccgcc tattgtcaat atcgatcaag ctgtagtaat catgtccgtc aaggaacctg
    19141 attttaacag caatttgctg gatcgtttct tggttctttt ggagcacaag ggcatccatc
    19201 ccattgtcta tatttccaaa atggatttgt tggaagatag gggagaactg gatttttacc
    19261 agcagaccta tggtgacatc ggctatgact ttgtgaccag taaagaggaa ctcctgtctt
    19321 tgttaacagg caaggttacg gtctttatgg ggcagacagg tgttgggaag tcaactcttc
    19381 tcaataaaat cgcaccagac ctcaatcttg aaacgggaga aatttcagac agtctaggtc
    19441 gcggtcgcca taccactcga gctgttagtt tttacaatct caacgggggt aaaatcgcag
    19501 atacaccagg cttttcatct ctggactatg aagtatcaag ggctgaagac ctcaatcagg
    19561 cctttccaga gattgctact gttagccgag attgtaagtt ccgtacttgt acccataccc
    19621 atgagccgtc ttgtgccgtc aaaccagctg ttgaagaggg tgttattgca accttccgtt
    19681 ttgacaatta cctgcaattc cttagtgaaa ttgaaaatcg tagagaaacc tataaaaaag
    19741 tcagcaaaaa aattccaaaa taaggagaaa cctatgtctc aatacaagat tgctccgtca
    19801 attctggcag cagattatgc caactttgaa cgtgaaatca aacgtctaga agcaactggg
    19861 gcagaatatg cccatatcga tatcatggac agtcattttg taccgcaaat cagttttggt
    19921 gcaggtgtgg tcgagagcct tcgtcctcat agtaagatgg ttttcgattg ccacttgatg
    19981 gtgtcaaacc ctgagcatca tctggaagat tttgcgcgtg caggtgcaga catcatcagt
    20041 atccatgtag aagcaacgcc tcatattcat ggcgccctcc aaaaaattcg ttcactcgga
    20101 gttaagcctt cagtcgttat caatcctggc acaccagttg aagccatcaa gcacgtcctt
    20161 catctagttg accaagtttt agtcatgacg gttaatccag gttttggtgg gcaagccttt
    20221 ctgccagaaa ccatggataa ggttcgtgag ttggttgctc ttcgtgagga aaaaggtttg
    20281 aactttgaaa tcgaagtgga tggtgggatt gatgaccaaa ctattgctca agccaaagaa
    20341 gctggtgcga ctgtttttgt agcaggttcc tatgtcttta agggagaagt caatgagcga
    20401 gtacaaactc tcagaaaaca actggactag ggttgcagtt tttgcaggcg gaaaccgcgg
    20461 tcattatcgg acagattttg atgcttttgt tggggtggat cgaggctcgc tctgggtctt
    20521 ggaagaagac ttacctcttg ctctagcagt cggagatttt gattctgtga cggaagaaga
    20581 gcgacaggtg attcaaaaac gtgcccagta ttttgtccaa gcccgaccag aaaaagatga
    20641 taccgatttg gaattggctc tcttaaccat ctttgagaaa aatcctcagg ctcaggttac
    20701 tattttcggt gccttgggtg gccgtattga ccatatgttg gccaatgtct ttctgcctag
    20761 caatcctaag ttggcaccct atatgcatca aatagaaatt gaggatgggc aaaacttgat
    20821 tacttattgt ccagaaggga ccagtcagct agaacctcgt tcagactacg actatctagc
    20881 ctttatgcca gttcgggata gccagctgac tattcttgga gccaagtatg agttgacaga
    20941 ggaaaatttt ttctttaaaa aagtgtacgc ttctaacgaa tatatagata gggaagtgtc
    21001 ggtaacttgc ccagatggtt atgtggtcgt actgcatagc aaggatagga ggtaggatgg
    21061 aaagtttact tattctatta ttaattgcca acctagctgg tctctttctg atttggcaaa
    21121 ggcaggatag gcaggagaaa cacttaagta agagcttgga ggatcaggca gatcatttgt
    21181 cagaccagtt ggattaccgc tttgaccaag ccagacaagc cagccagtta gaccaaaaag
    21241 atttggaagt ggctgtcagc gaccgtttgc aagaagtgcg gattgaattg caccaaggcc
    21301 tgacccaagt ccgtcaagaa atgacagata atctcctcca aactagagat aagacagacc
    21361 aacgtctcca agccttgcag gaatcaaatg agcaacgttt ggaacaaatg cgccagacgg
    21421 tcgaggaaaa actagaaaag accttgcaga cacgcttaca ggcttccttt gagacagttt
    21481 ctaaacaact ggagtctgtc aatcgtggtc ttggagaaat gcagacagtt gcccgtgatg
    21541 tcggagctct taacaaggtt ctctctggaa ccaagacgcg agggattctg ggagaattgc
    21601 aactggggca aattattgaa gacatcatga cacctgccca gtacgaacga gaatacgcaa
    21661 cggttgaaaa ctctagtgaa cgagtggagt atgccatcaa gttacccgga caaggcgacc
    21721 aagaatacgt ctatcttcca attgactcta agtttccact ggcagattat taccgcttgg
    21781 aagaagccta tgagacaggt gacaaggatg agattgaacg ctgtcgtaag tcactcctag
    21841 caagcgtcaa gcgctttgcc aaggatatca agagcaagta catagcaccg cctcggacaa
    21901 ccaactttgg aatcttgttt gttccgacag aaggtcttta ttcagagatt gtgcgcaatc
    21961 cggtcttctt tgatgatttg agacgggaag aacagattat tgttgcagga ccaagtaccc
    22021 tatcagccct tcttaactcc ctatcagttg gtttcaagac ccttaatatc caaaagagtg
    22081 ccgaccatat cagcaagact cttgccagtg tcaagaccga gtttggcaag tttggtggta
    22141 ttctggtcaa ggcacaaaaa catctccaac atgcctctgg caatattgat gaattattaa
    22201 accgtcgtac catagctatc gagcggacgc tccgtcacat tgagttgtca gaaggtgagc
    22261 ctgcgcttga tctactctat tttcaagaaa atgaggaaga atatgaagat tagtcacatg
    22321 aaaaaagatg agttatttga aggcttttac ctaatcaaat cagctgacct gaggcaaact
    22381 cgagctggga aaaactacct agcctttacc ttccaagatg atagtggcga gattgatggg
    22441 aagctctggg atgcccaacc tcataacatt gaggccttta ccgcaggtaa ggttgtccac
    22501 atgaaaggac gccgagaagt ttataacaat acccctcaag tcaatcaaat tactctccgc
    22561 ctgcctcaag ctggtgaacc caatgaccca gctgatttca aggtcaagtc accagttgat
    22621 gtcaaggaaa ttcgtgacta catgtcgcaa atgattttca aaattgaaaa tcctgtctgg
    22681 caacggattg tccgaaatct ctacaccaag tatgataagg aattctactc ctatccagcc
    22741 gccaagacca accaccatgc ctttgaaacg ggcttggctt atcatacggc gaccatggta
    22801 cgtttggcag acgctattag cgaagtttat cctcagctca ataagagctt actctatgcg
    22861 gggattatgc tgcatgactt agctaaggtt atcgagttga cggggccaga ccagacagag
    22921 tacacagtgc gaggtaatct tcttggacat atcgctctca ttgatagcga aattaccaag
    22981 acagttatgg aactcggcat cgatgatacc aaggaagaag tcgttttgct tcgtcatgtc
    23041 atcctcagtc accacggctt gcttgaatat ggaagtccag tccgtccacg tattatggag
    23101 gcagagatta tccatatgat tgacaatctg gatgcaagca tgatgatgat gtcaacagct
    23161 ctggctttgg tggataaagg agagatgacc aataaaatct tcgctatgga taatcgttcc
    23221 ttctataaac cagatttaga ttgataattt aagaaaaatg agcatttttt aggataagaa
    23281 tgttcgtttt tttatgtgaa tatggtataa taagtaaaag acaaaaatga atactcttcg
    23341 aaaatctctt caaactaggg tagtatcgcc ttgtcgtatg tatatatgca ggtatattac
    23401 agggtttgtc agttctatcg acaatctcaa agcagtgttt tgaaccacca gcgaccagct
    23461 ttctagtttg ctttttgatt ttttgaataa aaatggaata ggaaatagaa atgaaattaa
    23521 gaagaagtga tcggatggtt gtcatttcca actatttgat taataatcct tataaactaa
    23581 ctagtctcaa tacttttgct gaaaagtatg agtctgctaa atcatccatc tcagaagata
    23641 tcgtcattat caaacgcgcc tttgaggaaa ttgaaatcgg tcatatccag acagtgactg
    23701 gggctggcgg aggtgtcatc ttcacaccgt ctatttcgag tcaggatgct aaggaaatgg
    23761 ttgaagactt gcgtaccaag ttgtcagaaa gtgaccgtat cttgccaggt ggttatatct
    23821 atctgtctga tttgcttagc acaccagcca tcttgaaaaa tattggtcgt attattgcca
    23881 aaagctttat ggaccaaaaa attgacgcgg ttatgaccgt agcaactaag ggtgtgccac
    23941 ttgcaaatgc agttgccaat gtcctcaatg tctcttttgt cattgtgcgc cgtgacctga
    24001 aaattaccga aggttcaact gttagcgtca actatgtttc aggttcaagt ggtgaccgta
    24061 tcgagaaaat gttcctttca aaacgtagtc ttaaggcagg tagccgtgtc ttgattgtgg
    24121 atgacttctt gaaaggtggc ggaacggtca acggtatgat tagtctcttg cgcgagttcg
    24181 actcagaact ggcaggtgta gcggtctttg cggacaatgc ccaagaagaa cgtgaaaagc
    24241 agtttgacta caagtcactc ttgaaggtaa ctaatattga tgtcaagaac caagccatcg
    24301 atgttgaggt tggcaatatc tttgacgaag ataaataaga gatagaacta aaggttggaa
    24361 cgattgtccc agcctttctt tgcaaacaga atagaaggaa gcttatgaaa acaccattta
    24421 tcaatagaga agagttagaa gcgattgttg ccgagttccc gactcccttt cacttgtatg
    24481 atgagaaggg gattcgtgag aaggcaagag ccgtcaacca agctttttcg tggaacaagg
    24541 gctttaagga atattttgca gttaaggcta ctccaactcc agctattttg aaaattctcc
    24601 aagaagaagg ttgtggtgtg gactgctcta gttatgtaga gcttttgatg agccataaac
    24661 tggactttct gggttctgag attatgttct cttccaacaa cacgccagac aaggaatacg
    24721 cctatgcacg tgaattgggt gcgaccatta acttggatgc ctttgaagat attgaacatc
    24781 tggagagagt agcaggcatt ccagaaatca tctcttgtcg ttataatcct ggaggcgttt
    24841 ttgaactggg gacagacatt atggacaatc ctggggaggc taagtttggc atgaccaagg
    24901 accagctctt tgaagccttt gctatcttga aggaaaaagg agccaagact tttgggattc
    24961 actccttcct agcgtccaat accgtgaccc atctctatta tccagagttg gctcgtcagc
    25021 tctttgaact ggctgttgaa atcaaggaaa agttgggcat ttggctagac tttatcaatc
    25081 tttctggcgg tattggtgtt aattatcgtc cagaccagga gccgaacgat atcgccttga
    25141 ttggtgaggg agttcgtaag gtgtatgaag aagttcttac gtcagcaggt cttggtcagg
    25201 tcaagatttt caccgaattg ggtcgtttta tgctggcacc tcacggtgct ctagtcacaa
    25261 gagtgactca taagaaggaa acctaccgta cctatctagg tgtggatgcc tcagcagtca
    25321 acctcatgcg tccagctatg tacggagctt accatcatat tagcaacgtg acccatccag
    25381 atggaccagc tgaagcggta gatgtggttg gttcactctg tgaaaacaat gataaatttg
    25441 cagtcaatcg cgaactgcct catacagaaa tcggtgattt gctggtaatt catgatacag
    25501 gtgcccacgg attttcaatg ggctaccagt ataatgccaa attacgttct gcggaaatcc
    25561 tctataccga agaaggtaaa gcccgtcaaa tccgccgtgc agagcgccct gaggactatt
    25621 ttgcaacctt atatggcttc gattttgaag aataatctga taatagattg aaaatgaaat
    25681 tgaaaaacag attgctttct aaaaaatagg caaaaatctt gtttttcctt caagtcgtga
    25741 tataataaaa ctataaaacg ttttcaagga aggtaacgat atgtctgaag aaacaattga
    25801 ttatggacaa gtgacaggaa tggtgcattc gacagaaagc tttgggtcag tagatgggcc
    25861 tggtattcgc tttattgtct ttttgcaggg ctgtcacatg cgttgccagt attgccacaa
    25921 cccagacact tgggctatgg agtccaataa gtcacgtgaa cggacggtag atgatgtctt
    25981 gacagaggcc ttgcgctacc gtggtttctg gggaaataag ggtgggatta cagtcagtgg
    26041 aggagaagct ctcttgcaga ttgatttcct gattgctctc ttcaccaagg ctaaggaaca
    26101 aggaatccac tgtaccttgg atacctgtgc tcttcctttc cgtaataaac cacgttacct
    26161 tgagaagttt gacaaactca tggctgtcac tgacttggtt cttttggata tcaaggaaat
    26221 caacgaagaa cagcacaaga ttgtcactag acaaaccaat aaaaatatct tggcttgtgc
    26281 ccagtatcta tcagatattg gaaaacctgt ctggattcgc cacgtgctag ttccaggatt
    26341 gacagacaga gatgatgact tgattgaact tggtaagttc gtcaagaccc tcaaaaatgt
    26401 tgataagttt gaaattctac cttatcacac catgggtgag ttcaagtggc gtgaacttgg
    26461 aattccatat tccctcgaag gagtcaaacc accaacagca gatcgcgtca agaacgctaa
    26521 aaaactcatg gataccgaaa gttatcaaga ttatatgaaa cgtgtacatg gatagaaaag
    26581 aagcctgatg gaaacatcgg gcttttgatt tgcaaaaaga cttagcaaat cagctaagcc
    26641 tttttcttct tatctcgaac gttgttttcc agcgttgcga tttttgtgtt ttttcttgct
    26701 tgtgatagca gttggttgtt caggggtaac gtcttttcgt ccacttggtt tagagaaagc
    26761 acttgctttt ggtgggttct tggctagttc ttcacggact tttttgcgaa gttttggacg
    26821 aacgatatag ttgacgataa actgttggag aatcatcatg aaaccaccga caacccagta
    26881 aagtgtgaca ctagctggtg agaagaggga gaagacgacg atcatgagtg ggctcatgta
    26941 aatcattttc ttgatttgtt ctctttgcat ttcatcttct actccgtgaa gtgaaaggag
    27001 cgattgaaga tagtaaagga caccagcaca ggcaaccaaa atcatacttg gagaacctag
    27061 aggaatgcct aggtagcttg cttgagcaac cccttcagta tgttgggcag caaagtagat
    27121 agcagagaag aaaggcattt gaaggaggat agggaaacat cctacaccgc caaacatgct
    27181 gataccgtgc tctttttgag cagcaaagag agcttgttgg gcttcgagtt tttcttcttg
    27241 agtagtcgct tctttgagac gcgtttggtg tggctcaagg acgtgcttga gggcgttcat
    27301 cttttcagag tgaagcgttg ccttccatga ttggtagata ccaagtggca agataatcaa
    27361 gcgcacgata atggttacga tgatgatagc gacaccaaag cctagacctt tatcagtagc
    27421 gaagtacttg atagcttcag ccataggggc tccgatggta ttccaaataa atcctgttgg
    27481 ctgacctgtg gttttatcga cattgacaca accagtcaag acaagcaaca tagccgctcc
    27541 catagctgag agtgcaaaac gtttaataga tttcactgtt tttattcctt ctttaaaaat
    27601 tatacctttc tattctactg tttttttaca aaatatacaa tagttctgga gacctaattt
    27661 gcgattttaa agtcagagta gggaggaaag ttgcttagtt tgacatctaa gtagcttact
    27721 tttgaaaaag gtgtcggtcc ttttcggatt tcttggataa attttgccat gatagcagat
    27781 gagtctgctt gggctaagat ttccactgtg ccatcgtcgt tattccatac tcgacctgtg
    27841 atgccaccaa tttcaagtgc caagctgtaa acaccccaac gaaagccgac tccctgtacc
    27901 ctaccttggg caatcattct aaccttttgc ataccaaacc cctttgattg tgttataata
    27961 tttctatgac tattataacc tcaaaagcca attctgtggt aaaaaatgcc aagaaattac
    28021 gccaaaaaaa ataccgcaag tctgcctact tgattgaagg ctggcacttg tttgaagaag
    28081 ctgtccaagc tggagtgacg attgagaaaa tctttgccct agaaaattat cgagatcagt
    28141 tagctacttt ttcgcaaact gtctgggtgt cagaggatat tttgctagat ttggcggatt
    28201 ctcagactcc acagggaatt gttgccgtgg ttcaaaaaga agaagtagga caagctgatt
    28261 tgagtcaggg caagttcttg tttttggaag atgtgcaaga tcctggtaat gtaggaacta
    28321 tcattcgaac tgcggatgca gcaggtttta caggagtgat tgtttcagat aagtcggcag
    28381 acatctacag tctcaaaacc ctacgttcca tgcaaggtag tcatttccat ctgcccattt
    28441 accggatgac tagtcaagcg cttcttgacg aaactaaaaa ggtagctatc ccagtgctag
    28501 caacaaccct atctaaagat tctgttgatt acagagaact gccttctata gaaaattttg
    28561 tactagttat gggaaatgag ggtcaaggaa ttagtcccct tatggctgaa agtgcagacc
    28621 agttggtcca tattagcatg aaggggcagg ccgagagttt gaatgttgcg gttgcagccg
    28681 gtattttaat cttccattta agctaatttt aacttttttt gttataatca aggaaagatg
    28741 ttcacagaaa aggagaaatg gatgaatcac actattatac atgaccgtgc aggtctcaat
    28801 caattttacg ctaaggttta tgcctttgtt ggtctgggaa tcggactatc tgctttggta
    28861 tcaggcctta tgttgacggt ctttcagtct cagttggttt actttttgat gcaggggcgt
    28921 ctctggttga ccattgctac ttttgcggag ttggctttgg ttttcgttgc cagtagcatg
    28981 gcttcaagaa atagtccagc tgctcttcca gtatttttac tttactccgt tttaaacggc
    29041 tttaccctta gttttgtggt ggctttctat actccgggta cagttttatc tgcctttgta
    29101 tcgagcgccc ttctcttctt tgtcatggcg gcagttggta tttttaccaa gaaagacttg
    29161 agtgggattg gtcgagcaat gatggcagct ctcattggtt tactgattgc tatggtagtc
    29221 aatattttct tggctagtgg cttctttgat tatatgatta gcgtagccat ggttttggtt
    29281 ttttcagggt tgattgcttg ggataaccaa aagattcgcc tcgcctatga acaatcacaa
    29341 ggtcgtgtag cgacaggctg ggtggtgtca atggctctca gcatctatct tgattttatc
    29401 aatcttttcc taagtattct acgtatcttt ggtcgcaatg actaaaaggt ctatgaaatc
    29461 agtgttttga gtgacactga ttttttttaa attttctctt ttcttttctt ggaaataggt
    29521 gtataatacg tttattaaat ttttgaggag ttgtctatga agaaaagttt tatccatcaa
    29581 caagaagaaa tttcctttgt caaaaacact tttacccagt atttgaaaga taagctagaa
    29641 gttgtcgaag ttcaaggtcc tatcttgagt aaggtcggtg acggaatgca ggacaacctg
    29701 tctggtgtgg aaaatccagt atcggtcaag gttctccaaa tccctgatgc tacttatgaa
    29761 gtggtgcact cacttgctaa atggaaacgc cacaccttgg ctcgttttgg ctttggtgaa
    29821 ggagagggtc tctttgtcca catgaaagcc cttcgtccag atgaggattc cttggatgca
    29881 acccactctg tttatgttga ccagtgggac tgggagaagg ttatcccaaa tggtaagcgt
    29941 aacatcgttt atctaaaaga aacagttgag aagatttata aggctattcg cctgactgag
    30001 ctagctgttg aagcccgcta tgacatcgag tctatcttgc caaaacaaat cacctttatc
    30061 catacagaag aattggtaga acgctaccca gacttgacac ctaaagaacg tgaaaatgcg
    30121 atttgtaaag aatttggagc cgtctttttg attggtatcg gtggcgagtt gccagatggt
    30181 aaaccgcacg atggacgtgc accagactat gatgactgga caagcgagtc tgagaatggc
    30241 tacaagggtc taaatggtga tattcttgtc tggaatgagt ctttaggtgg agcctttgag
    30301 ttgtcttcta tgggaattcg tgtagatgaa gaaactctta gacgtcaggt ggaaattaca
    30361 ggtgatgaag accgcttgga attggaatgg cacaagtctt tgttgaatgg cctattccca
    30421 ttgacaatcg gtggaggaat tggacaatct cgtatggcca tgttcctact tcgcaagaga
    30481 cacatcggag aagtgcaaac aagtgtttgg cctcaagaag tccgcgatac ttacgaaaat
    30541 attttgtaga gaatcgaacc gcaaggttcg gttttctttc tctttttgtc tataatttgg
    30601 tataataaac agtatgaaaa tcgtatcagg aatctatggg ggacgtcccc tcaagacact
    30661 agaaggcaag acaacaagac ctacttcgga taaggttagg ggagccattt ttaacatgat
    30721 tggtccctac tttgaagggg gacgagtctt ggacctttat gcaggtagtg gtggtttatc
    30781 tatcgaagca gtatcgcgtg gcatgtccag tgctgttttg gtggagcgag accgtaaggc
    30841 tcagaccatc gtggctgaaa atatccagat gaccaaggaa gttggaaaat ttcaactcct
    30901 caagatggat gcagagaggg cattggaaca ggtatctggg gaatttgacc tcgttttctt
    30961 agaccctccc tatgccaagg aacaaatcgt agcagatatt gaaaaaatgg ctaagagaga
    31021 gcttttttct gaagatgtta tggttgtgtg cgagacggat aaggccgttg aacttccaga
    31081 agagattgcc tgtctgggta tctggaagga aaagatttat ggaattagta aggtgacagt
    31141 ctatgtcaga taagattggc ttattcacag gctcatttga tccgatgaca aatgggcatc
    31201 tggatatcat tgaacgggcg agcagacttt ttgataagct ttatgtgggt atttttttta
    31261 atccccacaa acaaggattt ctccctcttg aaaatcgtaa acgggggcta gaaaaggctt
    31321 tgggacattt ggaaaatgtt gaagtcgtgg cttctcatga tgaattggtg gtcgatgttg
    31381 caaaaagact gggggctact ttcctagtac gggggttgag gaatgcggcg gatttgcaat
    31441 atgaagctag ttttgattac tacaatcatc agctgtcttc tgatatagag actatttatt
    31501 tacatagccg gcctgaacat ctctatatca gttcatcagg tgttcgagag cttttgaagt
    31561 ttggtcagga tattgcctgc catgttcccg agagtatttt ggaggaaata agaaatgaaa
    31621 aaaaagatta gatggccctt atacgtcatt gcggccttga ttgtgacttt cttggcattt
    31681 gtagtgccct tgccttatta tatagaggtt ccaggtggtt cggaagatat tcgccaagtc
    31741 cttaaagtaa atgacacaga agataaggaa gctggtgcct atcaattcgt tacggttggt
    31801 gttcaacatg ccactttagc tcatatgatt tatgcttggt tgacaccttt tacagatatt
    31861 cgtagtgctc aggagactac aggtggttct tccgatgttg aatttatgcg aatcaatcaa
    31921 ttctacatgc aaacatcgca aaatatggcc aagtatcaag gactaaaaac agctggtaag
    31981 gatatcgaac tcaagtactt tggagtttat gttttgaatg tgacggataa ttcaaccttt
    32041 aaagggattc tcaatatctc tgatacagtc acagcagtca atgatcagac ctttgatagt
    32101 tccaaagact tgattgatta cgtcagttct caaaaattag gggattccgt caaggtcacc
    32161 tatgaagagg atgggcaaac caagtctgca gaaggaaaga ttatcacctt ggaaaatggc
    32221 aaaaatggaa ttggaatcgg cttgattgac cgtacagagg taatcagcaa tgtcccaatt
    32281 agcttttcaa cagctggtat tggcggccca agtgctggtc tcatgtttag tctagctatc
    32341 tatactcaaa tagctcaccc agatcttcgt aatggtcgta ttgttgccgg tacaggtacc
    32401 attgaccgcg atggtaatgt gggagacatt ggaggtattg ataagaaggt tgtagcttcg
    32461 gctagggcag gtgctgctat tttctttgct cctgataacc ctgttagcga agaagaacaa
    32521 aaggcgcatc tggacgcgaa aaacaactac caaacagccc tagaagcggc taaaacaatc
    32581 aagacggata tgaaaatcgt gcccgttaaa accctacaag atgcgattga ttacttgaaa
    32641 aacaatccct aatttttgag tgaagtttcc aaactagcgc acaaacagag aagatggtat
    32701 aatagtcaaa tggttcaatt attattcact ctaagtagtc atatgctctt tatttatgtg
    32761 agtttttacc ttttaaagga tcttgttaga tgggagaagg ttttaaaagt gacagatgat
    32821 aatacaagaa aagttcgttt attagtagcc ttttttagca ttgtcatagg ctacatcctg
    32881 agttctttct ttattagcct gtatcatttg tggcaagaag cgcttagagg attattataa
    32941 aatcaagagt aaaggaaacg agtatggata aaattgtggt tcaaggtggc gataatcgtc
    33001 tggtaggaag cgtgacgatc gagggagcaa aaaatgcagt cttacccttg ttggcagcga
    33061 ctattctagc aagtgaagga aagaccgtct tgcagaatgt tccgattttg tcggatgtct
    33121 ttattatgaa tcaggtagtt ggtggtttga atgccaaggt tgactttgat gaggaagctc
    33181 atcttgtcaa ggtggatgct actggcgaca tcactgagga agccccttac aagtatgtca
    33241 gcaagatgcg cgcctccatc gttgtattag ggccaatcct tgcccgtgtg ggtcatgcca
    33301 aggtatccat gccaggtggt tgtacgattg gtagccgtcc tattgatctt catttgaaag
    33361 gtctggaagc tatgggggtt aagattagtc agacagctgg ttacatcgaa gccaaggcag
    33421 aacgcttgca tggcgctcat atctatatgg actttccaag tgttggtgca acgcagaact
    33481 tgatgatggc agcgactctg gctgatgggg tgacagtgat tgagaatgct gcgcgtgagc
    33541 ctgagattgt tgacttagcc attctcctta atgaaatggg agccaaggta aaaggtgctg
    33601 gtacagagac tataaccatt actggtgttg agaaacttca tggtacgact cacaatgtag
    33661 tccaagaccg tatcgaagca ggaaccttta tggtagctgc tgccatgact ggtggtgatg
    33721 tcttgattcg agacgctgtc tgggagcaca accgtccctt gattgccaag ttacttgaaa
    33781 tgggtgttga agtaattgaa gaagacgaag gaattcgtgt tcgttctcaa ctagaaaatc
    33841 taaaagctgt tcatgtgaaa accttgcccc acccaggatt tccaacagat atgcaggctc
    33901 aatttacagc cttgatgaca gttgcaaaag gcgaatcaac catggtggag acagttttcg
    33961 aaaatcgttt ccaacaccta gaagagatgc gccgcatggg cttgcattct gagattatcc
    34021 gtgatacagc tcgtattgtt ggtggacagc ctttgcaggg agcagaagtt ctttcaactg
    34081 accttcgtgc cagtgcagcc ttgattttga caggtttggt agcacaggga gaaactgtgg
    34141 tcggtaaatt ggttcacttg gatagaggtt actacggttt ccatgagaag ttggcgcagc
    34201 taggtgctaa gattcagcgg attgaggcaa gcgatgaaga tgaataagaa atcaagctac
    34261 gtaatcaatc gtttactttt agtcatcata gtactgattt taggtactct ggctctagga
    34321 atcggtctaa tggtaggtta tggaatcttg ggcaagggtc aagatccatg ggctatcctg
    34381 tctccagcaa aatggcagga attgattcat aaatttacag gaaattaggc tggagaacca
    34441 gcctttttct aaagataagg agaaatatga acaaaaaaac aagacagaca ctaatcggac
    34501 tgctagtgtt attgcttttg tctacaggga gctattatat caagcagatg cagtcggcac
    34561 ctaatagtcc caaaaccaat cttagtcaga aaaaacaagc gtctgaagct cctagtcaag
    34621 cattggcaga gagtgtctta acagacgcag tcaagagtca aataaagggg agtctggagt
    34681 ggaatggctc aggtgctttt atcgtcaatg gtaataaaac aaatctagat gccaaggttt
    34741 caagtaagcc ctacgctgac aataaaacaa agacagtggg caaggaaact gttccaaccg
    34801 tagctaatgc cctcttgtct aaggccactc gtcagtacaa gaatcgtaaa gaaactggga
    34861 atggttcaac ttcttggact cctccaggtt ggcatcaggt caagaatcta aagggctctt
    34921 atacccatgc agtcgataga ggtcatttgt taggctatgc cttaatcggt ggtttggatg
    34981 gttttgatgc ctcaacaagc aatcctaaaa acattgctgt tcagacagcc tgggcaaatc
    35041 aggcacaagc cgagtattcg actggtcaaa actactatga aagcaaggtg cgtaaagcct
    35101 tggaccaaaa caagcgtgtc cgttaccgtg taacccttta ctacgcttca aacgaggatt
    35161 tagttccctc agcttcacag attgaagcca agtcttcgga tggagaattg gaattcaatg
    35221 ttctagttcc caatgttcaa aagggacttc aactggatta ccgaactgga gaagtaactg
    35281 taactcagta aaagataagc ctaaactcct atgtcactta tggatgtagg agttcttttt
    35341 actagtttaa gcagggctag aacaggtact aagaaaaaat agtaacttct aaaactaact
    35401 tccagtttcc cacaacctag cttttagtat gagaaaaacg cgtgaaatca gtggaaattc
    35461 gtcttagact aacttccagt tttgggagag agatggaagt tacgctaaga aaaaaataat
    35521 atgtattgga ttaaattttg tgatataata aaggataaga tactatttta ggagaagaac
    35581 tatggaagac ccaagtagtc agaatttgtt gctacaattt gttttattgt ttatcttgac
    35641 ggtattaaat gcctttttct cagccacaga aatggccatg gtttctctta atcgtgcccg
    35701 agttgaacaa aaggcggaag aaggagacag acgctacatc cgcctgctga aggtactaga
    35761 aaatcctaac cactttttat caaccattca ggtaggaatc accctgatta caatcttatc
    35821 aggggcgagt ttaactgata ctctaggacg tgtgattgcc tcttggcttg ggaatggcga
    35881 aacagcacaa gccgtggcaa cttttctatc cttggcattt ttgacctata tttccatcgt
    35941 ttttggggaa ttatatccta agagaatcgc tcttaatcta aaggatgcct tggcaattcg
    36001 tacagcgccg gttatcattg ggatcggaaa actagtcagt ccttttgttt ggcttttagc
    36061 tgcttcgacc aatttcttga gccatttgac tcctatgtca ttcgatgatg cggatgaaaa
    36121 gatgacccgt gatgaaattg cctatatgct gacaaatagt gaagaaacat tggatgctga
    36181 tgagattgag atgctacaag gtgtcttttc gctcgatgaa ctgatggcac gagaggttat
    36241 ggttcctcga acggatgcct ttatggtgga tattcaggat gatagtcaag ccattatcca
    36301 aagtatttta aaacaaaatt attctcgtat cccggtttat gatggggata aggacaatgt
    36361 aattggaatc attcacacca agagtctcct taaggcaggc tttgtggacg gttttgacaa
    36421 tattgtttgg aagagaattt tacaagatcc actttttgta cctgaaacta tttttgtgga
    36481 tgacttgcta aaagaactgc gaaataccca aagacaaatg gcaatcttgc tggatgaata
    36541 cggtggtatg gctggtttgg tgactttgga agacctctta gaggaaattg ttggtgaaat
    36601 tgatgatgaa acggacaaag cagcaataga tgttcatcag attggcgagg atacctacat
    36661 tgttcaagga actatgaccc tcaatgattt caataattac tttaatgttg aactggaaag
    36721 tgatgacgtt gatactatcg ctggttatta tttgacagga gtgggaacca ttccaacgac
    36781 tgagaaactc agctatgaat tgatcagcca aaacaaacag tttatcttaa ccaatgataa
    36841 agtgaagaat ggacgtgtta ccaaggtaaa aatccaaatc acagaagtcg aaatagaaga
    36901 agaaacagaa taaactagag gcttttgtca ccaggcgtga cgaagctttt ttcaattgat
    36961 ttcaaaaggg aattatgcca tggaaagaac tctgccacaa actcgctcca aaagttttta
    37021 aagttatacg tatttattcg agggaaaata agaaaagccc ttcaaattgg gctttctgtt
    37081 catttgaaac ctgataaatc aagttataga aggcggtaga cggatttgaa ccgacgatca
    37141 agcttttgca gagccgtgcc ttaccacttg gctataccgc cttaacgttt attattatac
    37201 cttgaaaatg attttcagtc aatagttttt tcagtttttt gtaccatagc gtgattcgaa
    37261 tgtgatgcca agttttctat gggaaaaaat ttaccaaaaa cctactgaaa ccccttgaaa
    37321 aatctagcta aatagggtat aatatgggta atcatttgtc gtaggttttg tctgaaatat
    37381 tgtccagaca aggctcacag cagttaaatc ttctgaaaaa gtcagattta gctgctcttt
    37441 ttgtgctttt tttcaagatt ttgagcattt gtaacagagg cttaaagatt ctgaaaattc
    37501 gtcaagagga cacggtgata aggggtttac aaccatatgg cgattagaaa agcctgattg
    37561 acaaggcttg gaacttattt acaaaggaga atcatcttgg caggacatga cgttcaatac
    37621 gggaaacatc gtacccgtcg tagtttttca agaatcaaag aagttcttga cttaccaaat
    37681 ttgattgaaa ttcaaactga ctcattcaaa gctttcctag accacggtct taaggaagtg
    37741 tttgaagatg tattgccaat ttcaaacttc acagacacaa tggagttgga atttgttgga
    37801 tatgaaatca aggaaccaaa atacacgcta gaagaagctc gtatccacga tgctagctac
    37861 tcagcaccaa tttttgtaac cttccgtttg atcaataaag aaacaggcga aatcaagacc
    37921 caagaagttt tctttggtga tttcccaatc atgacagaaa tgggtacttt catcatcaat
    37981 ggtggtgaac gtattatcgt ttctcagttg gtccgctcac caggtgttta ctttaacgac
    38041 aaagtagaca aaaatggtaa ggtgggctat ggttcaactg ttatccctaa ccgtggagct
    38101 tggttggaac ttgaaagcga ctcaaaagat atcacctaca ctcgtatcga ccgtactcgt
    38161 aagattccat ttacaacctt ggttcgtgct cttggtttct caggtgatga tgaaatcttt
    38221 gatatctttg gtgacagcga attggttcgc aacactgttg aaaaagatat ccacaagaat
    38281 ccaatggact ctcgtacaga cgaagccttg aaagaaattt acgaacgcct tcgtccaggt
    38341 gagcctaaga cggctgaaag ctcacgtagc ttgcttgtag ctcgcttctt tgacccacgt
    38401 cgttatgact tggcagcagt tggtcgttac aaaatcaata aaaaactcaa tgttaaaaca
    38461 cgtttgctca accaaaccat tgcagagcca ttggtagacc ctgaaactgg agaaatcttg
    38521 gtagaagctg gtacgattat gactcgtagc gtgattgaaa gcattgaaag ccatttggat
    38581 ggcgacttga acaagattgt ctacatccca aacgatgcag ccgttgtgac tgagcctgtt
    38641 gttcttcaaa aattcaaggt tattgctcca actgatccag atcgcgtcgt aacgatcatt
    38701 ggtaatgcta acccagatga caaggttcgt acggtgactc ctgcagatat ccttgctgag
    38761 atgagctact tcctcaactt ggctgaagga cttggccgtg tagatgatat cgaccacctt
    38821 ggaaatcgtc gtatccgtgc ggttggtgaa ttgcttgcca accaagtacg tttgggactt
    38881 tctcgtatgg aacgtaatgt ccgtgaacgt atgtctgttc aggacaatga agtcttgaca
    38941 ccacaacaaa ttatcaatat tcgtcctgta acagctgcag ttaaagaatt ctttggttca
    39001 tcacagttgt cacagttcat ggaccaacac aacccgcttt ctgagttgtc tcacaaacgc
    39061 cgtttgtcag ccttaggacc tggtggtttg actcgtgacc gtgccggata tgaagtgcgt
    39121 gacgtgcact acactcacta tggtcgtatg tgtccaatcg agacacctga aggacctaac
    39181 atcggtttga tcaataactt gtcatcttac ggacacttga acaaatatgg ttttgttcaa
    39241 acaccatacc gtaaggttga ccgtgaaaca ggtgttgtca cgaacgaaat tgtttggttg
    39301 acagctgatg aagaagatga atatactgta gctcaggcta actctcgtct gaatgaagat
    39361 ggaacctttg ctgagaagat tgtcatggga cgtcaccaag gggtcaacca agagtatcca
    39421 gctaatattg ttgactacat ggacgtttca ccaaaacagg tagttgccgt tgcgacagca
    39481 tgtattcctt tcttggaaaa cgatgactcc aaccgtgccc tcatgggagc caatatgcaa
    39541 cgtcaggctg tgccattgat taatcctcag gcaccttacg ttggtactgg tatggaatac
    39601 caagcagccc acgattctgg tgcggctgtg attgctcagt atgatggtaa agttacttac
    39661 gcagatgctg acaaggtaga agttcgtcgt gaagatggtt cattggatgt ttaccacatc
    39721 caaaaattcc gtcgttcaaa ctcaggtact gcttacaacc aacgcactct cgtaaaagtt
    39781 ggtgatgtcg ttgaaaaagg cgatttcatc gctgacggac cttctatgga aaatggagaa
    39841 atggcgcttg gacaaaaccc aatcgttgcc tacatgactt gggaaggcta caacttcgag
    39901 gatgccgtta tcatgagcga acgcttggtg aaggacgatg tctacacatc tgttcacctt
    39961 gaagaatacg aatcagaaac gcgcgataca aagcttgggc ctgaagaaat cactcgcgaa
    40021 attccaaacg ttggtgaaga tgccctcaaa gaccttgacg aaatggggat tatccgtatt
    40081 ggtgctgagg ttaaagaagg tgatattctt gtagggaaag taacacctaa gggtgagaaa
    40141 gatctttcag ctgaagaacg tctcttgcac gctatctttg gagacaagtc tcgtgaagtg
    40201 cgtgatactt ctcttcgtgt accacacggt gccgatggtg tcgttcgtga tgttaagatc
    40261 tttacacgtg taaatggaga tgagttgcaa tcaggtgtta acatgttggt tcgtgtttac
    40321 atcgctcaaa aacgtaagat taaggtcgga gataaaatgg ccggacgtca cggaaacaaa
    40381 ggggttgtct ctcgtatcgt tcctgtagaa gacatgcctt accttccaga cggaactcca
    40441 gtcgacatca tgttgaaccc acttggggtg ccatcacgta tgaatatcgg tcaggttatg
    40501 gagcttcacc ttggtatggc agctcgtact cttggtattc acattgcgac accagtcttt
    40561 gatggagcaa gttctgaaga tctttggtca actgttaaag aagcaggtat ggatagcgat
    40621 gccaaaacga tcctttacga tggacgtact ggtgaaccat ttgataaccg tgtttctgtt
    40681 ggagtcatgt acatgatcaa actccaccac atggttgacg ataaattgca cgcgcgttca
    40741 gtcggacctt actcaactgt tacccaacaa ccactcggag gtaaagctca gtttggtgga
    40801 caacgtttcg gtgagatgga ggtttgggct cttgaagcct acggtgcgtc aaatgtcctt
    40861 caagaaatct tgacttacaa gtctgacgat atcaacggac gtttgaaagc ctatgaagct
    40921 attacaaaag gcaaaccaat tccaaaacca ggtgttccag aatccttccg agttcttgtt
    40981 aaagaattgc aatctcttgg tcttgacatg cgtgtcctag acgaagatga ccaagaagtg
    41041 gaacttcgcg acttggatga aggaatggac gaagatgtca tccacgtaga tgaccttgaa
    41101 aaagcccgcg aaaaagcagc ccaagaggct aaagcagcct ttgaagctga agaagctgag
    41161 aaagcaacaa aagcggaagc aacagaagaa gctgctgaac aagaataagc agttcactta
    41221 gaatagaaag ggaagaaata gtggttgatg taaatcgttt taaaagtatg caaatcaccc
    41281 tagcttctcc aagtaaagtc cgttcatggt cttatggaga agtcaaaaaa cctgaaacaa
    41341 tcaattatcg taccttgaaa ccagaacgtg aaggactctt tgatgaagtg atctttggtc
    41401 ctacaaaaga ctgggaatgt gcttgtggta agtacaaacg cattcgttac agaggaattg
    41461 tttgtgaccg ctgtggggtt gaagtaacgc gtacgaaagt tcgtcgtgag cgtatgggac
    41521 atatcgaatt gaaagctcct gtatctcaca tctggtactt caaggggatt ccaagccgta
    41581 tgggcttgac ccttgatatg agccctcgtg ccctcgagga agttatctac tttgcggctt
    41641 atgtggtgat tgatcctaag gatacaccac ttgagcacaa gtctatcatg acagagcgcg
    41701 aataccgaga gcgcttgcgc gaatatggtt atggttcatt tgttgccaag atgggtgcgg
    41761 aagccatcca agaccttttg aagcaagtag atcttgaaaa agaaattgct gaactcaaag
    41821 aagaattgaa aacagctact ggacaaaaac gtgtcaaagc catccgtcgt ttggatgttt
    41881 tggatgcctt ttacaagtct ggaaacaaac ctgaatggat gattcttaac atccttccgg
    41941 ttatcccacc agatcttcgt ccaatgttgc agttggatgg tggccgtttt gcctcatctg
    42001 acttgaatga cctttaccgc cgtgttatca atcgtaacaa ccgtttggct cgtttgcttg
    42061 agttaaatgc accaggtatc atcgttcaaa atgagaaacg tatgcttcaa gaagcagttg
    42121 acgctttgat tgacaatggt cgtcgtggtc gtccaatcac aggaccaggt agccgtccat
    42181 tgaaatcatt gagccacatg cttaaaggta aacaaggacg tttccgtcaa aacttgctcg
    42241 gtaaacgtgt tgacttctca ggacgttcag ttatcgccgt tggtccaact cttaagatgt
    42301 accaatgtgg tgtgccacgt gaaatggcga ttgaactctt taaaccattt gtcatgcgtg
    42361 aaatcgttgc ccgtgatatc gtgcaaaacg tcaaagcagc taaacgcttg gtggaacgcg
    42421 gagatgagcg tatctgggat atccttgaag aagtgattaa agaacaccca gtgcttttga
    42481 accgcgcacc gacccttcac cgtttgggta tccaagcctt cgagccagtc ttgattgatg
    42541 gtaaggctct tcgcttgcac ccacttgtct gtgaagccta caatgctgac tttgacgggg
    42601 accaaatggc catccacgta ccactttcag aagaagcaca agcagaagct cgtatcctca
    42661 tgctagctgc tgagcacatc ttgaacccga aagatgggaa accggtagtt actccatctc
    42721 aggacatggt tttgggtaac tactacttga ccatggaaga agctggtcgc gaaggtgaag
    42781 gaatggtctt caaagaccgt gacgaagcgg ttatggctta ccgcaatggt tatgttcacc
    42841 tccactcacg tgttggtatc gcaacagaca gcctcaacaa gccttggaca gaagagcaaa
    42901 gacataaggt cttgcttaca acagttggta aaattctctt caacgatatc atgccagagg
    42961 ggctaccata cttgcaagaa ccaaacaatg ccaacttgac agaaggtgtt ccagctaaat
    43021 acttcttgcc acttggtgga gatatcaagg aagctatcag caatcttgag ctcaaccctc
    43081 cattcaagaa gaaaaacctc ggaaatatca tcgctgaaat cttcaaacgt ttccgtacga
    43141 cagaaacttc tgccctactt gaccgcatga agaacctcgg ttaccaccac tcaactcttg
    43201 caggattgac agtgggtatt gccgatatcc cagtcgttga tgacaaggct gaaatcattg
    43261 aagaatcaca caaacgtgtc gaacaaatca ccaaacaatt ccgtcgtggt atgatcacag
    43321 acgacgagcg ttacaatgct gttacagctg aatggcgtgc tgcccgtgaa aaacttgaga
    43381 aacgcttgat tgctaatcaa gatcctaaga acccaatcgt tatgatgatg gactctggag
    43441 cccgtggtaa catctcaaac ttctcacagc ttgccggtat gcgtggtctg atggctgctc
    43501 cgaatggacg tatcatggaa ttgccaatcc tttcaaactt ccgcgaaggt ttgtcggtat
    43561 tggaaatgtt cttctcaact cacggtgctc gtaaaggtat gaccgatacg gcccttaaga
    43621 cagccgactc aggttacttg actcgtcgtt tggtcgacgt tgcccaagac gttatcatcc
    43681 gtgaggacga ctgtggaact gaccgtggtc tcttgatccg ttctatcgca gaaggaaaag
    43741 agatgatcga gtctctcgaa gagcgtctca acggtcgtta cactaagaaa actgttaaac
    43801 atccagaaac tggtgcagtg attattggtc caaatgaatt gattacagaa gacaaggcgc
    43861 gtgaaattgt caatgctggt gtggaagaag tgactatccg ttctgtattt acatgtaaca
    43921 ctcgtcacgg tgtctgccgt cactgttacg gtatcaactt ggcgactggt gatgcggttg
    43981 aagttggtga agcagttggt acaatcgctg cccaatctat cggggaacct ggtacacagc
    44041 ttacaatgcg taccttccac acaggtgggg ttgcctcaaa taccgatatc actcagggtc
    44101 ttcctcgtgt ccaagaaatc tttgaagccc gcaatcctaa aggggaagcg gttatcacag
    44161 aggttaaagg acaagttact gctatcgaag aggatgcatc aactcgtacc aagaaagtct
    44221 ttgttaaggg tgaaactggc gaaggtgaat atgtcgttcc atttacagct cgtatgcgtg
    44281 tcgaagttgg gggccaagta gcgcgtggtg ctgctctgac agaaggttct atccaaccaa
    44341 aacgtctcct tgcagttcgt gatgtcttgt cagttgaaac gtaccttctc ggtgaagtac
    44401 aaaaagttta ccgtagccaa ggggtagaaa tcggtgacaa acacatcgag gtaatggttc
    44461 gtcaaatgat ccgtaaagtc cgtgtcatgg atccaggtga tacagatctt ctcatgggta
    44521 ccctcatgga tatcaatgac tttacagatg ccaacaaaga tgtccttatc gcaggtggag
    44581 ttccagcgac aggtcgccca gtccttatgg gaattaccaa agcctcactt gaaacaaaca
    44641 gtttcttgtc agcggcttcc ttccaggaaa caactcgtgt ccttactgac gcagctatcc
    44701 gtggtaagaa agaccatctc cttggactta aagaaaatgt tatcatcggt aagatcatcc
    44761 cagctggtac tggtatggcc cgttaccgta accttgaacc acatgctgtc aacgaagaag
    44821 aataccttaa tcctccagta gaggaagaag gaaatgaaga aacaacagaa gtagttgtgg
    44881 atactgccgt tgaaactgtg gaagaaacag tagaataaga gagaatgaga gaaccctcgg
    44941 gttctctcat tctctcttct gaaaactttc tccatttttc cacgaaatgt ggtaaaataa
    45001 aagaaagaag ctgacaaagg agacgggtat ggaacaaaca ttctttatca tcaaaccaga
    45061 tggtgtaaaa agagggctag tgggtgaagt gttaaagcgc atcgaacaac gtggatttac
    45121 aatcgaaaaa ttggagtttc gttcacaggt ttcagaagag ttgattgacc agcactatca
    45181 ggacttggtt ggtcagagtt tttacccacc gattcgtgaa ttcatgactt caggtccagt
    45241 tcttgtgggt gtcatttctg gtcccaaagt aatcgaaact tggcggacca tgatgggtgc
    45301 aactcgtcca gaagaagctt taccaggcac tattcgaggt gattttgcaa aagctgctgg
    45361 agaaaatgag attatccaaa atgttgtaca tggttcagat tcagaagagt cagctaagcg
    45421 agaaattgct ctttggtttt aagagtggat tggctcaatc aattggttaa aagctcattt
    45481 gaatagaaag tatagtcaat tagtttaaga catgacgcat gatatcaaac tttttagttt
    45541 ttgatatggt gcgttttttg attaagtgac tattagtttg tctcgctccg ttaggtgcga
    45601 gacaaaaaaa acacccgcta tgcgggtgcg cgtcgaaggt tataccaaaa aaactccaaa
    45661 cgcgatacaa taaaggtgtt caatccaatt gtaaagcgaa aggagaaaaa tatggcacaa
    45721 aaggttcttt tatcctgttc ttgtttcaat tgactatatt tctatacttt ttcttccttt
    45781 ctctgtgaaa atcgcaagtt tttcccacct tttctcaata ctgaaacaac atctttccag
    45841 aacttcaata atttcttttt gtgttaaatc attatttaac taaatctttg gaggcaatac
    45901 gttttcaaag ctactttttt accataggtt ttgagccttc aacacagatt actaagccaa
    45961 aaatgctcta aatttttgaa attctaacaa attccactca actttatcat catctttgac
    46021 tttcacaata tcttcctcaa aataacatgg aataaagata gttttctttt aaaacggttg
    46081 taggaggaaa atctctccta cactattatt gattctgaga gaaaattgca aaatatcatc
    46141 taccaaactt tcaattatta agattttttg cagtttatct gaattagaat cgcaaggctt
    46201 ctcaataata taattgtcga attttttcat tctaacttcc tctccattat ttcttccttt
    46261 atcaagaaaa agttacctca atattaataa agtacaattc taaattaact ccaattcttg
    46321 attcatgata atatttcagt aactcatcgt gcaattaaaa acaaggattt ttatttcaga
    46381 tgatccatcg tgaacacttc atcagccatc tcccaaattg ccggattatg tgttgcgata
    46441 atgattagcc tattatcatc tcgaagagat agcaaaatct ccataatcaa ctgagaggtt
    46501 gctgggtcta ttgaagctgt tggctcatct gccagaataa agggtggatt ctttaagata
    46561 atttttgcca aggcaacccg ttgcgattct ccgcccgata actcaaagat gcgcttatct
    46621 aggtcaagat aagccaggcc gacctgttct aaagcctgct tctgcctcaa ccgctgttcc
    46681 gaccgactca acttttgacc aatgagacct agcttaaggt tttcttcaat actttggttt
    46741 tcaattaagc caaagttctg gaagaggtag cccaattcgt gacggaaaaa atcactcgat
    46801 ttataattgg ccaagtcttt acctcggtaa aaaatcgtcc catcataagg ttctaatttc
    46861 ccaatcatgt tcatcaaggt tgtttttccg ctaccacttg aaccaattaa ggcatagact
    46921 tttccagcct caaatgtcat tgaaagattc gaaaataact ctcgttctcc aaaagattta
    46981 ctcacctgtt taagttcaat catattaacc tcccttcaaa acaagaatgg acatcttgtt
    47041 ttctttctgc atttggacat gtaactgtaa aagagataga ccagtaaaga gtaacaagac
    47101 taagaaagca actcctatct ctacctgaag aaatacactc gcaacaaatc ccagtaaaaa
    47161 cacacccagt tgagcaaaga gataagtgcg atggatttct aagaacctga gacctgcaat
    47221 gcgtttgata aaaatggcac gtctaaattc ttcaaagtag agcctattca tagtgttaaa
    47281 caacaagatt gaagttgcaa tcccaagcac agctcctgct agcattaccc aacgttccct
    47341 ctggatatta tccaataatg tgatgtagtt gtggtaacct gtttgcattt ctgagaccca
    47401 attttcaatg ccttgtctct ggataagctc ctgggcatca gacaattgat taaagagaac
    47461 gtagttctgt actgcgtcta tccaaaacaa aatggactgt ggaccagttg attggggtgt
    47521 tataacaatg atgattggat ctttcaaaaa ctgctggtaa gaaatagggg tcgtattata
    47581 cacaaaacga tcctgacctg attctaaata acctaccgta gcagtcattt gctgtcgttc
    47641 atcttgacta gacatgcgac tggttaagtc gtcttcaaaa acagatttat aatgttcttc
    47701 ctctgaacgg aggtgttcag gcagcaataa gacaaactcc cctacattaa ggtgattcat
    47761 cttttgctca atagttgtat ctacaggaat gttttgacgc tccaagtatt gcggtgtgac
    47821 gataaggaca ttgccattcg ggttgtaatc gtgccattct gtagaggtta tcaagttttt
    47881 ggaggaagcc atgccatttt gcaaagtacg gtcaattaac tggtgtctag ataagaaagc
    47941 cttttgttct gaaacagcca gatccatcaa ttgataccaa gttctgagtt tcctttgagc
    48001 ttgttcatca aaaccaggac tcgttccttc acggctgatt gatagggtaa tcagttgcct
    48061 ttcctgactc caagcctctt gtccaatccg atgctgttgc caggcttggg aatactttaa
    48121 gctactccct attcccagcg ttacaataat aatcgctaat agttgaccga ttaaaatcaa
    48181 actaatgatt cctctgacag gcacttgccc ttttataatc tgcatcaggt gtatcttttt
    48241 tatcccaact gcgaagagtt gagcgaaaaa cagggagatc gacaacaaga tgagattata
    48301 actgagcaag cctgctccta tggtcattag ggattgcgtt ggaagcgaca gaattttttg
    48361 cataagaatg gcgagcacgc cagctaaact gaaaccaaca gctatccctt tcaaatcctc
    48421 accaactggt ctaaggaaaa tggaccaccg tttctctcct gaaatgaggc gaatgcccga
    48481 cgaccgtaat tggctaattt gactaattaa agtcagtgct acaaaggtta agatgaaaat
    48541 caatagactg attaactgaa atccgttact aaagatagcc attaacgtag atagtttaga
    48601 tggaattgtc aggttcatgt tagtcaagcc aagttgactt agctcctccc ttagcaagtg
    48661 aatatctagg tgtccatcga atacaaaata gtttgtttca acactactac tttgagcatc
    48721 ttctagtttt ttttcctgaa gcccatcagg caactttccg tccccaaagg tcgtataaga
    48781 aaaaactgta gtaccttctg agttagaatc ttggtgttga atcgcaataa agctatctgt
    48841 ttcttctgct agtttttcca agcgtgtagc aacatgctga aaagttgttt caggggaaga
    48901 atcacgtaca acaacgttgg ggtaataatg ggagacatat gtatcagtcc aaatggtaaa
    48961 tacccaaaca aagaacaaac tagcaagcag gttggatatg agtataaata attttttcat
    49021 agtgcattcc ttattctaaa acagagggca gaaatacccc tgccctctat aaactaacaa
    49081 gcttactaaa ctattgataa aagaatcttc ttcaattatt ctttaccatc ccgcatcaaa
    49141 tctaaatttt aacatattat tactcctctg aatgaaatat tatgaaaatg agcgaaatgc
    49201 aactacatat tttaattaga aatctcagtc tgaattatag tatcctattt tttcctcctt
    49261 tctaactgca cgttcctttc tacaggcaga gacctaattt tataaaccaa tcttaaatac
    49321 tttagatttt gtaactcata attttcaaca gttggttagc tatgaaagca ttttatcaaa
    49381 catctccatt cttatatcta tctggtattg ttacaagctc tcatcagaat acctttctct
    49441 aaatagttga attttaaagt aatacgaaat caatcagcct tcccaacatc aagaccattg
    49501 gacttctttt gtgattgcac tcgaatctcc aattgtctat tcttctgaat aaactgttgg
    49561 taaggaattg tgttactaaa cataaaaaca cctagtaata ctaatatagc taatttttga
    49621 attccacgat ttttcttcat tcgtgaaacc cttttctt
//
LOCUS       DAVLTG010000009        48732 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLTG010000009 DAVLTG010000000
VERSION     DAVLTG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.009"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(145..2034)
                     /locus_tag="VYN12_000554"
     CDS             complement(145..2034)
                     /locus_tag="VYN12_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1414988.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2172..3737
                     /locus_tag="VYN12_000555"
     CDS             2172..3737
                     /locus_tag="VYN12_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1414989.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3737..4477
                     /locus_tag="VYN12_000556"
     CDS             3737..4477
                     /locus_tag="VYN12_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1414990.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4586..4801)
                     /locus_tag="VYN12_000557"
     CDS             complement(4586..4801)
                     /locus_tag="VYN12_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414991.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5672..6922)
                     /gene="ilvA"
                     /locus_tag="VYN12_000558"
     CDS             complement(5672..6922)
                     /gene="ilvA"
                     /locus_tag="VYN12_000558"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1414992.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6972..7328)
                     /locus_tag="VYN12_000559"
     CDS             complement(6972..7328)
                     /locus_tag="VYN12_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1414993.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(7566..7802)
                     /locus_tag="VYN12_000560"
     CDS             complement(7566..7802)
                     /locus_tag="VYN12_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1414994.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(7909..8931)
                     /gene="ilvC"
                     /locus_tag="VYN12_000561"
     CDS             complement(7909..8931)
                     /gene="ilvC"
                     /locus_tag="VYN12_000561"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1414995.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(8997..9473)
                     /gene="ilvN"
                     /locus_tag="VYN12_000562"
     CDS             complement(8997..9473)
                     /gene="ilvN"
                     /locus_tag="VYN12_000562"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1414996.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9466..11166)
                     /locus_tag="VYN12_000563"
     CDS             complement(9466..11166)
                     /locus_tag="VYN12_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1414997.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11366..13033)
                     /locus_tag="VYN12_000564"
     CDS             complement(11366..13033)
                     /locus_tag="VYN12_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1414998.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13036..13401)
                     /locus_tag="VYN12_000565"
     CDS             complement(13036..13401)
                     /locus_tag="VYN12_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1414999.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13558..13746)
                     /locus_tag="VYN12_000566"
     CDS             complement(13558..13746)
                     /locus_tag="VYN12_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1415000.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13862..14038)
                     /locus_tag="VYN12_000567"
     CDS             complement(13862..14038)
                     /locus_tag="VYN12_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1415001.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAISLAAVRDDFYTHNFNSGILLIN
                     NGMWRAENVTQDLI"
     gene            complement(14149..14346)
                     /locus_tag="VYN12_000568"
     CDS             complement(14149..14346)
                     /locus_tag="VYN12_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1415002.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14600..16144)
                     /locus_tag="VYN12_000569"
     CDS             complement(14600..16144)
                     /locus_tag="VYN12_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1415003.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16357..16659
                     /gene="gatC"
                     /locus_tag="VYN12_000570"
     CDS             16357..16659
                     /gene="gatC"
                     /locus_tag="VYN12_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1415004.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            16659..18125
                     /gene="gatA"
                     /locus_tag="VYN12_000571"
     CDS             16659..18125
                     /gene="gatA"
                     /locus_tag="VYN12_000571"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1415005.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN"
     gene            18125..19567
                     /gene="gatB"
                     /locus_tag="VYN12_000572"
     CDS             18125..19567
                     /gene="gatB"
                     /locus_tag="VYN12_000572"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1415006.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19696..20256
                     /gene="efp"
                     /locus_tag="VYN12_000573"
     CDS             19696..20256
                     /gene="efp"
                     /locus_tag="VYN12_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1415007.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20278..20667
                     /locus_tag="VYN12_000574"
     CDS             20278..20667
                     /locus_tag="VYN12_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1415008.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20660..21082
                     /gene="nusB"
                     /locus_tag="VYN12_000575"
     CDS             20660..21082
                     /gene="nusB"
                     /locus_tag="VYN12_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1415009.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21129..21365)
                     /locus_tag="VYN12_000576"
     CDS             complement(21129..21365)
                     /locus_tag="VYN12_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1415010.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21378..21851)
                     /locus_tag="VYN12_000577"
     CDS             complement(21378..21851)
                     /locus_tag="VYN12_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415011.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(21869..22054)
                     /gene="briC"
                     /locus_tag="VYN12_000578"
     CDS             complement(21869..22054)
                     /gene="briC"
                     /locus_tag="VYN12_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1415012.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22213..22980)
                     /locus_tag="VYN12_000579"
     CDS             complement(22213..22980)
                     /locus_tag="VYN12_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1415013.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIISIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(22977..23843)
                     /locus_tag="VYN12_000580"
     CDS             complement(22977..23843)
                     /locus_tag="VYN12_000580"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1415014.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23880..25247)
                     /gene="accC"
                     /locus_tag="VYN12_000581"
     CDS             complement(23880..25247)
                     /gene="accC"
                     /locus_tag="VYN12_000581"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1415015.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25259..25681)
                     /gene="fabZ"
                     /locus_tag="VYN12_000582"
     CDS             complement(25259..25681)
                     /gene="fabZ"
                     /locus_tag="VYN12_000582"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1415016.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSENTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(25678..26163)
                     /locus_tag="VYN12_000583"
     CDS             complement(25678..26163)
                     /locus_tag="VYN12_000583"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1415017.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26166..27401)
                     /gene="fabF"
                     /locus_tag="VYN12_000584"
     CDS             complement(26166..27401)
                     /gene="fabF"
                     /locus_tag="VYN12_000584"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1415018.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEVNVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27423..28154)
                     /gene="fabG"
                     /locus_tag="VYN12_000585"
     CDS             complement(27423..28154)
                     /gene="fabG"
                     /locus_tag="VYN12_000585"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1415019.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28188..29108)
                     /gene="fabD"
                     /locus_tag="VYN12_000586"
     CDS             complement(28188..29108)
                     /gene="fabD"
                     /locus_tag="VYN12_000586"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1415020.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSNFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29101..30075)
                     /gene="fabK"
                     /locus_tag="VYN12_000587"
     CDS             complement(29101..30075)
                     /gene="fabK"
                     /locus_tag="VYN12_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1415021.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30194..30418)
                     /locus_tag="VYN12_000588"
     CDS             complement(30194..30418)
                     /locus_tag="VYN12_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1415022.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30478..31452)
                     /locus_tag="VYN12_000589"
     CDS             complement(30478..31452)
                     /locus_tag="VYN12_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1415023.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31452..31886)
                     /locus_tag="VYN12_000590"
     CDS             complement(31452..31886)
                     /locus_tag="VYN12_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1415024.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(31980..32765)
                     /locus_tag="VYN12_000591"
     CDS             complement(31980..32765)
                     /locus_tag="VYN12_000591"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1415025.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33135..34499
                     /locus_tag="VYN12_000592"
     CDS             33135..34499
                     /locus_tag="VYN12_000592"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1415026.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34502..34873
                     /locus_tag="VYN12_000593"
     CDS             34502..34873
                     /locus_tag="VYN12_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1415027.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35087..36361
                     /gene="serS"
                     /locus_tag="VYN12_000594"
     CDS             35087..36361
                     /gene="serS"
                     /locus_tag="VYN12_000594"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1415028.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36386..37285)
                     /locus_tag="VYN12_000595"
     CDS             complement(36386..37285)
                     /locus_tag="VYN12_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1415029.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37395..37943)
                     /locus_tag="VYN12_000596"
     CDS             complement(37395..37943)
                     /locus_tag="VYN12_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1415030.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNSTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38161..39483)
                     /locus_tag="VYN12_000597"
     CDS             complement(38161..39483)
                     /locus_tag="VYN12_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1415031.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKHAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39574..39662)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39826..42162)
                     /locus_tag="VYN12_000598"
     CDS             complement(39826..42162)
                     /locus_tag="VYN12_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1415032.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42266..42814)
                     /locus_tag="VYN12_000599"
     CDS             complement(42266..42814)
                     /locus_tag="VYN12_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1415033.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42811..43113)
                     /gene="zapA"
                     /locus_tag="VYN12_000600"
     CDS             complement(42811..43113)
                     /gene="zapA"
                     /locus_tag="VYN12_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1415034.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43200..44081
                     /locus_tag="VYN12_000601"
     CDS             43200..44081
                     /locus_tag="VYN12_000601"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1415035.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44085..44699
                     /gene="lepB"
                     /locus_tag="VYN12_000602"
     CDS             44085..44699
                     /gene="lepB"
                     /locus_tag="VYN12_000602"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1415036.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44827..47193
                     /locus_tag="VYN12_000603"
     CDS             44827..47193
                     /locus_tag="VYN12_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1415037.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGITGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDRVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(47241..48524)
                     /locus_tag="VYN12_000604"
     CDS             complement(47241..48524)
                     /locus_tag="VYN12_000604"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1415038.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYSKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        14262 a        11180 c         9181 g        14109 t
ORIGIN      
        1 ggctttttgc cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa gaaatagttt
       61 agataaaact attgactttt cttatagttt gtctttcttc tatcttccat tatatcatac
      121 tttttcagtc tatggtagct ctctttaaaa ggctccgata ctgccgccac ctccgcctcc
      181 agagaagcca ccaccagaac ttccacttcc agaagataca gagtaggtac ttgctgtatt
      241 tgcgacacta gcataatggc tcatttgcgc gcttgaatga taaaacatac tgtgccagcc
      301 ataagctaca tagagattga tatctggatt ttcaacttga atctgatgaa ccttcatcaa
      361 atgactaacc ttgtccgcat agccaaataa ggttgcatag accaagagac gattccaaac
      421 aacaatactt tccaattcag ccttatccag tcgtgcaatc tcacgtaaca tattttcaaa
      481 actggtccag agatagtaga cctcagctcc cgcttcattt agaacaccat cacgattatc
      541 tagtcgaagc ttccaataat agaaaacaga caaaactaac cctagaaaac caagtattgg
      601 caaagggagg taaagatagc catgaacgtc taaactgtac aagaacaaac caaatccgat
      661 aaataggggc aagatagtca agacacccat acccacttgc aaagcctttt ccaaaccagt
      721 taaaggacga tagtaatctg ggagtcccca gaagacaact cgctttctca ctccttcttg
      781 catctctttt aatactgctt cgaaagaaga tttgagctga atccctcttg cttgaatccg
      841 tttctcatca gcagctttag ctccgcgata aaggctgtca gataccttgt aatccgcaaa
      901 caaattggaa agagtggctt cttttttgcc tgaaaaggct agatttagac agtctctctc
      961 aaatcttgac aaaccatctt ctttcaccaa tctcaagcca actgcatctc cttctgaaat
     1021 aatagaaaca ttcccacggt ccatcacatc tagcaaggta gcttgaataa gttggtcaaa
     1081 agtgaatttg ccagccccct tgactaaggg actcacttcc tccaaggagg tcgagtagac
     1141 agcctctgat aaaaccatag gctctaattc cattggtggt tcatagagac gatgattttt
     1201 ggcatatttg actgaaggag tggtctttct tctataaata aaatagaagc agacactcaa
     1261 taacaaggag atagaaagga tcgaagggag gacccaagta acaagttgtt tactctgatc
     1321 tttttctcta acaatcgagt cttctatctt attaaactct tctaaacgat tccctttcaa
     1381 tccctgatcc ctagcgctag caaaatcggt ccgaggccag taggcatgca actcaactcc
     1441 acgcttagcc ggaagattgt ctaaacggat agtataatca aggttactct tttcaatcgt
     1501 tccctctcta aaaagtttcc ctgtatggaa aaagagtttt tcagccccct tgtctcccct
     1561 tacatgaaat tcaaactttt caatagactc tgaactatct gtcagaggtt gccaatttaa
     1621 ttcagcgata tcatcataaa ggaaaagtaa attttttaag ttccagacga ggtcaacttc
     1681 aactatgtcg ccctcctgac ctggattata gactctcaca gtataaccat ccgcttcttc
     1741 tgttacttcg ctagtcacat ctgctagttc tgcaccgttt ttcgcggcct gaacctttgg
     1801 atgagggtca atgtcaaacc cgctaggcat cttaccagca cgtccaagtc ccacgatttg
     1861 tcccttaaag tcctcctcaa actggtaaac tatcttctgt ctaaactctg ccgtattatc
     1921 tgcatgaata tacaaatccc cttgataaga gtttatcttg aaatcaatgg caaaaacaga
     1981 gagtggaaga aggcaaaaca agcctaacac cagtaagaaa aaagtttttt tcatcaacta
     2041 agcccccttt ttatctttct tatcattata gcattttttc gtaagtaaag gcttacttat
     2101 gttgaaaaat tacgcatttt tcgataaaat aggagacagt tattttttaa tagatcagaa
     2161 taggagaaat catgagaaaa atatacttat ctattttcac aagtctcttg ctgatgctag
     2221 gacttgtcaa tgttgctcaa gccgatgaat atttacgcat cgggatggaa gcagcatatg
     2281 ctccctttaa ctggacccag gatgatgata gcaacggagc tgtcaaaatc gatgggacca
     2341 atcagtatgc caacggatac gatgttcaaa tcgccaagaa aatcgctaag gacttaggta
     2401 aagaaccttt ggttgttaaa accaagtggg aaggtctagt ccctgccctt acttctggta
     2461 agattgacat gattatcgca ggtatgagtc caactgcaga acgcaaacaa gaaattgcct
     2521 tttcgagcag ttactacact agcgaaccag ttttgcttgt caaaaaagat tctgcctacg
     2581 caagtgctaa atctttggat gactttaatg gtgcgaaaat cacttctcaa caaggtgtct
     2641 acctctacga cttgattgca caaatcccag gtgctaaaaa agaaacagcc atgggagact
     2701 tcgctcaaat gcgccaagct cttgaggctg gtgtcattga tgcttatgtt tctgaacgtc
     2761 cagaagcact gactgctgaa gctgcgaact ctaagttcaa gatgattcaa gtagaacctg
     2821 gtttcaaaac tggggaagaa gatacagcta tcgctatcgg gcttcgtaaa aatgacaatc
     2881 gtattagcca aatcaatgcc agcattgaaa ccatttcaaa agatgaccaa gttgccttga
     2941 tggatcgtat gatcaaggaa caacctgccg aagctacaac aactgaagag actagcagta
     3001 gtttctttag ccaagtcgct aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg
     3061 ctggtatcac tcttttaatc tctatcgtcg gaaccatcat aggtctcatt attggacttg
     3121 ccattggtgt cttccgtact gctcctctct ctgaaaacaa agccatttat ggccttcaaa
     3181 aactagtcgg ctgggttctc aatgtctaca ttgaaatttt ccgtggtacg ccaatgattg
     3241 ttcaatcgat ggttatctac tatggaactg cccaagcttt cgggatcaac cttgaccgta
     3301 cactggctgc tatcttcatc gtttcaatca ataccggtgc ctacatgact gaaatcgtcc
     3361 gtggtggtat cctagcagtt gacaagggac aatttgaagc tgcgactgct cttggtatga
     3421 cccataacca gaccatgcgt aagattgtcc tacctcaggt agtccgtaac atcctacctg
     3481 caactggtaa tgaatttgtc atcaatatca aagatacatc tgtattgaac gttatctctg
     3541 ttgtcgaact ttatttctca ggaaataccg tggcaacaca aacctatcaa tacttccaga
     3601 catttacaat catcgccgtg atttactttg tcctcacctt caccgtaaca cgtatcctac
     3661 gatttatcga gcgccgaatg gacatggata cctatactac aggtgctaac caaatgcaaa
     3721 cggaggattt gaaataatga cacaagcaat ccttgaaatt aaacacctca aaaaatccta
     3781 tggacaaaac gaagtgctaa aagacatttc actcactgtc cacaagggag aggtcatctc
     3841 tatcatcgga agctctggaa gcggaaaatc gaccttccta cgctccatta acctacttga
     3901 aacaccaact gatggacaaa tcctttatca tggacaaaac gtcctcgaaa aaggctatga
     3961 cctcacgcaa taccgtgaaa agttggggat ggttttccaa tcctttaacc tctttgaaaa
     4021 tctcaatgtt cttgaaaaca caatcgtcgc tcagacaact gtcctaaaac gcgaacgcac
     4081 agaagctgaa aagattgcca aagaaaacct ggaaaaggtc ggcatgggag aacgctactg
     4141 gcaagccaaa ccaaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca tcgctcgtgc
     4201 cctctccatg aatccggacg ctattctctt tgatgaacca acatcagctc tcgatccaga
     4261 aatggttgga gaagtcctca aaatcatgca ggacctggct caggaaggct tgaccatgat
     4321 tgtcgtaacc catgaaatgg aatttgcccg tgatgtctct caccgtgtta tctttatgga
     4381 taagggcgtg atcgctgaag aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga
     4441 ccgaacaaaa gagttccttc aacgctatct caaataaaaa gaaaaggctg catcaaccgt
     4501 gcagtctttt tgctgtcctc aaaatgaaaa ggcagattct ctatctctac tacttgaagg
     4561 tcaagaatcc gccgttatcc aaagattaat cttcaaattt ttcataattt ttttcataga
     4621 aatcaattaa gcctagggct gtttcaaatg aaatattttt tacttttgca cgaccctgcg
     4681 ccagagcaat gatagacatt tcacgcgcat tcgtttcttt agagatacgg tagcctgtga
     4741 ttttcttatc acgaacccag ccaacaactg attctacttt ttcaaagttt gacttagcca
     4801 tgtttttctc ctattttctt ctttataata tttaattgta tacgttttta ctacttttgt
     4861 caataaaaaa aacatatatt caacgaaaat aattagttca gaattttctt acttcctttt
     4921 taaatccgat aatatatagg ttttgctagc ctctacacca taaatatttg ctaataaaac
     4981 tactgtatta ttaccctctt aaggtgcgaa attattcaag ttcttaaaaa atgcttctct
     5041 atttccgtaa gatagcttat ttcttcgatt taagaactga agatgatagt tctaaccttt
     5101 agaaatccaa gccttcacta gctcaaaaac tcctatcttt cttcctcaat aaatcatctg
     5161 agagataggt atttcttata tccttcaaat tcatcactcc tttggatatt gaggtgctag
     5221 cctagaagca gacacccgat tatctaaacc atccttaata gagatgacaa gacagataag
     5281 ctcagttaat tacttatata tctttttaat atggtatatt tgtcaacaaa aagaaatcaa
     5341 atcatacctt atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaagttgct
     5401 caaaacactg ttttgaggtt gcagatagag ctaacgtggt ttgaagagat tttcgaagag
     5461 tattaaagac agtgtgacta tgcttgtcaa tagataggaa atcaaaatga aggatggaaa
     5521 tctgagccaa acatcataag tgctataatg aacagaagta agaattgcac gataagtttt
     5581 ctaaaaccat aggaatcgtc ccctttcttc atcttcatta tagcatatat acatcagttg
     5641 tacaaataat atgatatttt tttattagtc ctcagacaag catattataa agcgtttcat
     5701 taccatttaa gttaatataa gctggatcaa aaccttccat tctacgaatc aaacctgcat
     5761 aatcatgctt atctgctaaa gcgatcccaa tcaatactgg gcctgttccc ttgctagctc
     5821 gtttgatata ctcaaaacgt gtgatatcat catttggccc caggatatca tttacaaact
     5881 cacgcaaagc tcctggacgt tgtgggaaat tgaccacaaa ataatgtttg ataccatcat
     5941 aaatcaaggc acgctcttcc atttctggca tacggttgat atcattattt cctccagaaa
     6001 tgatacaaca aatggttttc cccttaatat attcagctaa aacctctaaa gaggcgatac
     6061 tagctgctcc agcaggttct gcgactatcc cttgcttaga gtaaaggtca atcaaggttt
     6121 cagaaatcaa tccctcatcg acacctacca aagtttgaat atgttgacga gttgcttcat
     6181 aggtcaactg acctaccttt tgcacagcaa tcccatccgc aaatttatca atttccttga
     6241 gtttgactgg acctccagcc tcaaaggcag ctttcatgga acgcgctcca ttcgcctcta
     6301 ctccgataac ctcaatctct ggacttgttt ccttgatata ggtagaaacc ccggcaatga
     6361 gaccgccacc accaacagga accaagacag catcaaaatc aatcgattct tttcgagctt
     6421 cttctaaaat ctcataagca actgttcctt gacctgcttg aacatgagca tcatcaaaag
     6481 gatcaataaa ggtacgattt tcagagactg taaattcttg agctgctttg gctgaggcat
     6541 caaaggtatc tccaactagt ttaatagtta caaaatcccc accaaaaaag cgaacctgac
     6601 caatcttttg ttgtggcgta gtaatgggca taaagatagt agcaggaatt ttcatttcat
     6661 tacaagtata ggctactccc tgcgcatgat ttcccgcaga agcgcaaact accccacgtt
     6721 cacgttcttc cttgctgagc tgggaaatgg cataataggc accacgaatt ttaaaggagc
     6781 gaacacgctg ggcattttct tttttcaaat aaatcttagc accatacttc tccgataaat
     6841 aatgatcgta atccagtgga gtattcacaa ccacaccgtt caagaccttg tgagccttga
     6901 ttatatcttt tgaacttaac atataaaacc tctttttcta taaaaaacag tcactaatga
     6961 ctgtttttta gttattcatc tccgaaaatt tcagtaacac tttcatggta tttatgagcc
     7021 atacgaatcg aaaactcttt aggaagttca taacgatttg tggaaatcca atcatataac
     7081 cattctacca aactttcttc actatcatta cgatggaaga taaaatagtt taaaatttct
     7141 ttatattcta catcattcaa atccaacgtg tctacaaatt gactacgagg aacaaaatta
     7201 gaatctaatt ttcttagttg atctgtcaat tctcccaatt gtaaatccaa ctgaaaaaat
     7261 agtttttgca gttgcctatc agtttcatca catcctgtct tgatagaaaa caaattggta
     7321 atattcatat gatttcaacc cctaaataag tacatctaat atcccacgaa tagctgaagc
     7381 taaagttttc gcagtccagt catttaaacc cgattctttc aatccagatg caataatttg
     7441 ctctatttga tataaaccgc catctatcgt ctcatttatt ctgcgaagag gaccttcaat
     7501 ataggataaa gcttctccga atctaacagc tgatttaggt cctaatgatt taccaactat
     7561 atttgttaat attttttatt tctcaaaatc catttcgcta tataacgagc agatttagtc
     7621 gcaccagctc tctcaaacgg agaatgaatt tcaagacctt cttctctagc tatttgtgcc
     7681 aatttgaaga attgttcaaa ggtcatatgc aacctaccat cttcaaaatt agcatcatca
     7741 taaatgttaa ttacagcatt ttcatcatac gaccaatctg ctttattttg gtctgctagc
     7801 actattaccg acggtgtaat tacattatac aactagaacc aataataacg atgcaatttt
     7861 tctcataatc tttttcataa aatcatctcc agcgctatat atttctaatt agttatagat
     7921 tttgaatgca tcatcgtcgt ttttaccaac gaatggcatt gctttacgca attctgcacc
     7981 aactttttca atttcaaggt tagctgcttg ttcacggtaa gcagtcaatt ttggacgtcc
     8041 agctttatag tcatttacaa agtcatttgc aaatttacca ttttggatgt ctgccaagac
     8101 agccttcata ttttctttaa cttgttcagt gattacacgt ggacctgata catagtcacc
     8161 gtattcagca gtgtttgaaa tagattgacg cattttcttg aatccacctt cgtagatcaa
     8221 gtcaacgatc aatttcattt cgtgaagaac ttcaaagtaa gccaattctg gagcgtaacc
     8281 tgcttctgtc aagacttcga aacctgcttc gataagggca gtcaaaccac cacaaagtac
     8341 agcttgttca ccaaacaaat cttcttcagt ttcttctttg taagttgttt caagaagacc
     8401 tacacgagcc gctccaacac ctttacacca gtccatagca atgtttttag catttcctgt
     8461 tgcatcttgg tatactgcat aaagagctgg aacaccaaat ccttcttcgt aagtacgacg
     8521 taccaagtgt cctggtcctt taggagcaca catgaagaca tctacatccg caggaacttt
     8581 gataaattca aagtggatgt tgaaaccatg ggcaaatcca actgcgtttc cagcttccaa
     8641 gtttggagcg atttctgctt cgtacaattc ttgttgaatt tcgtctggcg ccaagatcat
     8701 gataacatca gccaacttag tagcttctgc tactgtgtaa gtatcaaatc catcttcttt
     8761 tgctttatca aaagatttac ctggacgtac accgataata acgtcacgac ctgaatcacg
     8821 caagttttga gcatgcgcat gcccttgtga accataaccg ataacggcga tttttttacc
     8881 gtcaagtgct gctactttaa catctttttc atattccatt tgaactgtca tagcttttct
     8941 ctcttttcta ttatttattg ccttttaagc tggtttaaca aatttaagtt ggatttttaa
     9001 tcgcgggtaa atccagttgc acccgttcga gcaatattgc gaataccgta tgggcgaatg
     9061 actcgcaata gggcttcgct cttttctgca tttcccgtca tctgaatggt aatcgagctt
     9121 ggcgctacgt ctaccactgt tgcacggaaa ggttgaataa tcgctaaaat ctcagctctc
     9181 ttctcagctg gcgctgacat cttaaccaaa atcacctcgc gctccaaatg aggcttgtct
     9241 gtaatatctc gaatgcgaat cacatcaatc tgacgattga gctgtttgat gatttgctcc
     9301 acttcatcat gagaagcaac atcaataata atagtgatac gcgatacatt cggatcttct
     9361 gttgctccaa cagagatgct ttcaatatta acctgacgac gagataggac acctgtaaag
     9421 cgattgagga ctcctgaacg attttgtagt tttgctgtta acattctacg catggaactg
     9481 cacccccaac atctcatgat tactcttacc agccggtacc attggtaaca cctgttcctt
     9541 acgagaaata tctacctcaa ttagcatagg aacatcctca gtgatgactt caaggtcttg
     9601 agccaaggtc tcaggattgt caaacttata gtttttaata ccataagcct gcgccatcaa
     9661 ttggaaatca ggaagggtat caaagaccga ctctgatgtt ctgccttcat agaaggattc
     9721 ctgccactgg cgaaccattc cgagtgaatg attgttcagc ataaccacct tgattggcac
     9781 cttgtaaata ttcaaaatag ccaactcctg gttggtcatt tggaaaccac catccccaac
     9841 aaacaagact acttccttat ctgggttagc aattttagca ccgattgctg ctggaattcc
     9901 aaagcccatt gttcccaaac cacctgaagt cactaactga cgttcatttt ggtagggata
     9961 atactgagct gtccacattt ggtgttgacc aacgtctgtt accacaatgg catctccatt
    10021 cgtcaattca ccaattcgtt caataactgc ttgcggttga accacacgct ctttcttgtc
    10081 atacgaacga acacgattct tgtctttagt gactttctca atccactttt cagtattgtt
    10141 gtgaactgtt ggttctgcta gcaacatttg caaggccttc ttagcatctc caactacagg
    10201 aatgtctgca ctgataatct tgccaatctc agctgggtca atatcaatgt gggcaacctt
    10261 agcattctta gcgaaagtct taggattccc cgtcaaacgg tcatcgaaac gagaaccaat
    10321 actaatcata aagtccgctt ccgtcatggc aatatttgct gcgaatgacc cgtgcatgcc
    10381 tcccattcca agaaagagtg ggtgactcgt tgcaatcgtt ccttgtccca aaagactggt
    10441 taccactgga atttgatagc gttctgcaaa ttcatttagt tccgtagcag cctcagcata
    10501 actaattcca ccaccagcta acaagactgg ctttttagcc ttggacaatt gcttcaagat
    10561 tttcttgatt tgcatatcat tcggctcaag agtcggctga taacttggta aattcacttc
    10621 tggtgaataa atgaagtctg tttctaaagc agatatgtct tttggtaggt caattacaac
    10681 tggccctgga cggcctgtag ttgcgatatg gacagcttcc gtaatgatac gcggaatatc
    10741 agctgtctca cgaacttggt aattgtactt agtgattggc atggtaattc ctacgatgtc
    10801 tgcctcctga aaggcatcct tcccaatccc tgctcgcgcc acctgacctg taaagaccaa
    10861 aaggggaacg ctatcgctca tagcatccgc aatccctgta atggcatttg ttgctcctgg
    10921 tccactagtg acgacggcaa cacccaactt tccagttgat ttggcatagc cttcagcttc
    10981 atgcaaacaa ccttgctcat ggcgccctag aatgtggcga atgcctttaa aattatatat
    11041 cgcatcataa aaaggcaaaa ccgcaccacc aggataacca aagatggtat caactcctaa
    11101 atcacgaagt gtttccaaaa ctaggtccga ccccgtctta ggagattcta aactgatttt
    11161 ctccattatt cccctttctt tcctcttaaa aataacttgt tactatcata ccattttttc
    11221 aaaatttttc aagataaaag aagaaatttt ctgaattttc tattttaacg tttatttatg
    11281 aatgttattt ttgtttttat taaaaagata ccgatttcat ttactaaaaa gaaaaaagaa
    11341 ctgatttctc agtccttcat taatcttatt ccacactaaa taggtatggg taaacaggtt
    11401 gttgaccttg gtgaatctcg acttcaacgt cttcgaattc ttctacgatt tcttgagcga
    11461 tttcattggc aagttcttcg cttccgtctt caccgacata gaaggttacg atttcactgt
    11521 cttcatccaa catatgtttc aaggtttcag tcaatgtttg gtgcatatca gggtttgaca
    11581 caagaatttt tccatccacc atacctaaat tatcgttttc atggatttct aagccatcga
    11641 tcgttgtatc acgcacggct gttgtgacgc ttccgctaac gacatcgcta agagcagctg
    11701 tcatacgctc ttggttttct tcaatggact tgcttggatc aaaggcaaga agacttgtca
    11761 taccttgagg aagagtgcga gcctctacca ctaccgctgg ttgctccaaa acttctgccg
    11821 cagattgagc tgccatgaag atgttcttgt tgtttggcaa gaagatgatg ttacgggcat
    11881 taacctgttc aacagccttg ataaagtctt ctgttgaagg gttcatggtt tgaccgcctt
    11941 cgataacata atccacgcct tgagaacaga agatatctgc tagaccttta ccagccacca
    12001 cagcaatcaa agcatactct ttttcttcag ccgacttgat aacttgagta gcttctttct
    12061 caacctgtgc ttcgtgttgg ttacgcatat tgtcaacttt taccttgacc aagctaccat
    12121 atttgagacc ttcttgcata acaagtcctg gatcttctgt atgaacatgg actttgacaa
    12181 tttcatcatc gttaacaacg aggagagaat ctccaagctc atccaagtag ttacggaatt
    12241 catcgtagtc aaaatcttta gcataggttg gaccttgctt aagagctacc atgatttcag
    12301 tacagtaacc aaacgtgatg tcctcagtcg ctacgtgacc agctacagac ttatgatgct
    12361 ctacattgat catctcactc atgttggcag gagtcgctac aaagtcctca gatgcaatat
    12421 attcgccagt aagggctgaa aggaaacctt cgtagatgaa gaccaatcct tgaccacctg
    12481 agtccacaac gccaacttct ttcaatactg gaagcatgtc tggtgtttta gctagagctg
    12541 ttttagcacc ttccaaggct gcgcgcatga cttcaacagt gtcatctgtt tgctcagctt
    12601 ttttcttagc accgatagca gctccacgag aaactgtcaa aatcgttcct tcaacaggtt
    12661 tcatcactgc cttataggca acttccacac ctgattggaa ggccagagcc aagtcttgac
    12721 ctgttaactc gtctttatcc ttgatagctt gggaaaatcc acggaaaagc tgagacgtaa
    12781 tcactcctga gttcccacgc gcacccatca aaagcccttt ggcaagaatg ctcgctactt
    12841 ctccaactgt agaagctggc ttgtctgcaa cttctttagc accattttca atggtcattc
    12901 ccatatttgt cccagtatct ccatctggaa ctggaaagac gtttaatgaa ttgacatatt
    12961 cagcttgctt attcaagcga gttgatgcag cctgcaccat ttcttgaaat aagctagtag
    13021 taatttttga cacggttatt ctcctacaac tttgatattt tgaatgtaga catttacagt
    13081 ctgagcagta attccaagct ggttttccaa gctaaaggca acacgctctt gaatgttttt
    13141 tgacacttca ctaatctttg ttccgtagct taacacggta tatacatcaa ctgcaatact
    13201 gccatcttcg gctgccttta cgacgacacc tttagaataa ttttccttac ctagcagggc
    13261 ttggaaatta tctttgaggg catttttact agccataccg accacaccaa aaatctcagt
    13321 tgctgctcca cctacgacgg ttgcaatcac ttcatctgtt agttcgattt gaccatcttt
    13381 tgtattaatt tttacagtca tcctttttac ctcaactagt tgatactcta ttttatcata
    13441 tttcagccca agtgtaaaag cagaatgatg tatcagcgga tatttactct atttttcaaa
    13501 cgatgttata cccacaataa aagaaaaaag accctaaggt ctcctttgct tttattatta
    13561 aacgcgttca actttacctg atttcaaagc acgagctgaa gcccaaactt ttttaggttt
    13621 accatcgata agaacagtaa ctttttgaag gtttggtttt acggcacgtt ttgtttggtt
    13681 catcgcgtgt gaacggttgt ttcctgatac agtcttacga cctgtaaagt aacatacttt
    13741 agccattgtg ttttcctcct attagatcta atatagcgga tgtgctagca ccacataccg
    13801 tactatgtta tcacactttc ttattttttg caagggaatt ggaagatttt ttatttgtgt
    13861 cttaaatcag gtcttgcgtg acattttctg ctctccacat gccattgttg attaacagaa
    13921 taccagaatt aaaattatgt gtataaaaat catctctaac tgcagctaag gatatagccg
    13981 tcaagtccaa atcccacagc tcatctatcg attttcttac aacaatatct gaatccaaat
    14041 acagtacacg agactcgctt acatactttg gaataaaata cctaaaaaag ccgcatatga
    14101 aagtccctca aaggggagac gataaccttt cagaatacta ctgtcaatct aaacattcac
    14161 aatctcacta ttcaaagtct ctagtctttt ttccattaat tggaaccatt ctcgcggaag
    14221 gtcatcatta aaaacataaa acttaagatt ataatgatga acacaaagag attttattgt
    14281 tgtttcaact ttatccatat aagcattatc tgcacctaag acaatcgctt ttttctcttc
    14341 tttcactttt tatctcattt cttttattcc catcatatgt ttctacgtaa ccattatttt
    14401 cgcctattcg ttcgtaaaac cataccagtg gagattttag atgaagtccc attacggttt
    14461 acaattttta cattacgaca cggagtttgg caaatcgatt ctatttgcca aacgtagtta
    14521 gtgaggcagt tagctagttc gccaaatagc gactagcgtc caacaatttg gaactttagt
    14581 tccaattgtt ggtactgagt cacatcttct cctctaactc tacgtctgga tacttgtccg
    14641 caaaccagcg gagggcaaag tcattttcaa agagaaagac tggttggtca aaacggtctt
    14701 tggctaagat attgcgactt gacgacatcc gttcatccaa gtcctcaggc ttgatccaac
    14761 gaacggtctt tttacccatt gggttcataa ctacttctgc attgtactcg ccttccatgc
    14821 ggtgtttaaa gacttcaaac tggagttgac ctacagcgcc tagcatgtac tcacctgttt
    14881 ggtaattctt ataaagctga acggctcctt cttgcaccaa ttgctcaatc cccttgtgga
    14941 aggatttttg cttcataaca ttcttagcag aaactttcat gaaaatttca ggagtaaagg
    15001 ttggcagtgg ttcaaattca aacttgtttt taccaactgt caaggtatcc ccaacttgat
    15061 aagtaccggt atcgtaaacc ccgataatat cacctgccac ggcattgatc acattctcac
    15121 gactttccgc cataaactga gtaacattag acagtttagc ccccttacca gtacgaggga
    15181 gattgacact catgccgcgc tcaaattcgc cagatacgat acggacaaag gcaatacggt
    15241 cacggtgacg agggtccatg ttggcttgga ttttaaagac aaatcctgag aaatccttgt
    15301 cataaggatc cacaatttca ccgtctgttt tcttgtgacc atgtggttct ggagcaaact
    15361 tgaggaaggt ttcaaggaag gtctgcacac caaagtttgt cagggctgaa ccgaaaaaga
    15421 caggcgtcaa ttctccagcc agaatagctt cctctgaaaa ctcattcccg gcttcattta
    15481 aaagctcaat atcatccttg acttgctcgt agaaaggatt gctaccaaaa agtttgtccc
    15541 catcttctag actggcaaaa cgctcatccc ctttataaag ctctaaacgt tggttataga
    15601 ggtcatacaa gccctcaaag gctttcccca tcccgatagg ccagttcata gggtagctag
    15661 caatgcccaa gatttcttcc aattcttgta agagatccaa aggctcacga ccgtcacggt
    15721 ccagcttgtt cataaaggta aagactggaa tgccacgatg tttcacaacc tcaaacaatt
    15781 tcttggtttg agcctcgatc cccttggcag agtccacgac catgaccgca gcatccaccg
    15841 ccatcaaggt acgataggta tcttctgaga agtcctcgtg ccctggcgtg tctaagatat
    15901 tcacgcgctt gccgtcgtag tcaaattgca taacagatga agtaacagaa atcccacgtt
    15961 gcttctcgat atccatccag tcagatttag caaaagtccc tgttttcttc ccttttaccg
    16021 taccagcctc acgaatctca cccccaaagt agagtaactg ctcagtgatg gttgttttcc
    16081 ccgcgtccgg gtgggagata atggcaaagg tacgacgttt cttaatttct tcttgaatat
    16141 tcataagttc tctttctttg attctctatt tttcttgttt caatagctga gaatgatttt
    16201 tacattggat tttaccattc ctttcaacac tccattatat cggattttag catttttttc
    16261 aatttctatt tcttttcact tccccctccc ttatttatag gaaaatatgg taaaatagaa
    16321 cagactaaaa atcatcattt cacgaaagga tgcaagatga aaattacgca agaagaggta
    16381 acacacgttg ccaatctttc aaaattaaga ttctctgaaa aagaaactgc tgcctttgcg
    16441 accaccttgt ctaagattgt tgacatggtt gaattgctgg gcgaagttga cacaactggt
    16501 gtcgcaccta ctacgactat ggctgaccgc aagactgtac tccgccctga tgtggccgaa
    16561 gaaggaacag accgtgatcg cttgtttaaa aacgtacctg aaaaagacaa ctactatatc
    16621 aaggtgccag ctatcctaga cgatggagga gatgcctaat gacttttaac aataaaacta
    16681 ttgaagagtt gcacaatctc cttgtctcta aggaaatttc tgcaacagaa ttgacccaag
    16741 caacacttga aaatatcaag tctcgtgagg aagccctcaa ttcatttgtc accatcgctg
    16801 aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc tggaattgat gctgacaatg
    16861 tcctttcagg aattccactt gctgttaagg ataacatctc tacagacggt attctcacaa
    16921 ctgctgcctc aaaaatgctc tacaactatg agccaatctt tgatgcgaca gctgttgcca
    16981 atgcaaaaac caagggcatg attgtcgttg gaaagaccaa catggacgaa tttgctatgg
    17041 gtggttcagg tgaaacttca cactacggag caactaaaaa cgcttgggac cacagcaagg
    17101 ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc ctcaggacaa gttcgcttgt
    17161 cacttggttc tgatactggt ggttccatcc gccaacctgc tgccttcaac ggaatcgttg
    17221 gtctcaaacc aacctacgga acagtttcac gtttcggtct cattgccttt ggtagctcat
    17281 tagaccagat tggacctttt gctcctactg ttaaggaaaa tgccctcttg ctcaacgcta
    17341 ttgccagcga agatgctaaa gactctactt ctgctcctgt ccgcatcgcc gactttactt
    17401 caaaaatcgg ccaagacatc aagggtatga aaatcgcttt gcctaaggaa tacctcggtg
    17461 aaggaattaa cccagaggtt aaggaaacca ttctaaatgc cgctaaacac tttgaaaaat
    17521 tgggtgctat tgtcgaagaa gtcagccttc ctcactctaa atacggagtt gccgtatact
    17581 acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg ctttgacggt atccgttacg
    17641 gctatcgcgc agaagatgca accaaccttg atgaaatcta tgtaaacagc cgaagccaag
    17701 gttttggtga agaagtgaag cgccgtatca tgctgggtac tttcagtctt tcatcaggtt
    17761 actacgatgc ctactataag aaggctggac aggtccgtac acttatcatt caagatttcg
    17821 aaaaagtctt cgcggattac gatttgattt tgggtccaac tgctccaagt gttgcctatg
    17881 acttggattc tctcaaccat gacccagttg ccatgtactt agccgaccta ttgaccatac
    17941 ctgtaaactt ggcaggactg cctggaattt cgattcctgc tggattctct caaggtctac
    18001 ctgtcggtct gcaattgatt ggtcccaagc actctgagga aaccatttac caagttgctg
    18061 ctgcctttga agcaacaaca ggctaccaca aacaacaacc cgtgattttt ggaggtgaca
    18121 actaatgaac tttgaaacag tcatcggact tgaagtccac gtagagctca acaccaattc
    18181 aaaaatcttc tcacctactt ctgcccactt cggaaatgat caaaatgcca acactaacgt
    18241 gattgactgg tctttcccag gagttctgcc agttctcaat aaaggggttg tcgatgccgg
    18301 aatcaaggct gctcttgccc tcaacatgga catccacaaa aagatgcact ttgaccgcaa
    18361 gaactacttc taccctgata atcccaaagc ctaccaaatt tctcagtttg atgagccaat
    18421 cggttataac ggctggattg aagtcgaact agaagacggt acgaccaaga aaatcggtat
    18481 cgaacgtgcc cacctagagg aagacgctgg taaaaacacc catggtacag atggctactc
    18541 ttatgttgac ctcaaccgcc aaggggttcc cttgattgag attgtatctg aggcagatat
    18601 gcgttctcct gaagaagcct atgcttatct gacagccctc aaggaagtta tccagtacgc
    18661 tggcatttct gacgttaaga tggaggaagg ttcgatgcgt gtggatgcca acatctccct
    18721 tcgtccttat ggtcaagaga aattcggtac caagactgaa ttgaagaacc tcaactcctt
    18781 ctcaaacgtt cgtaaaggtc ttgaatacga agtccaacgc caggctgaaa ttcttcgctc
    18841 aggtggtcaa atccgccaag aaacacgccg ttacgatgaa gcgaataaag caaccatcct
    18901 catgcgtgtc aaggaagggg ctgctgacta ccgctacttc ccagaaccag acctacccct
    18961 ctttgaaatt tctgacgagt ggattgagga aatgcggact gagttgccag agtttccaaa
    19021 agaacgtcgt gcgcgttatg tatctgacct tggtttatca gactacgatg ctagtcagtt
    19081 gactgctaat aaagtcactt ctgatttctt tgaaaaagct gttgccctag gtggtgatgc
    19141 caaacaagtc tctaactggc tccaagggga agtcgctcag ttcttgaatg ctgaaggtaa
    19201 aacactggaa caaatcgaat tgacaccaga aaacttggtt gaaatgatta ccatcatcga
    19261 agacggtact atttcatcta agattgccaa gaaagtcttt gtccatctag ctaaaaatgg
    19321 cggtggcgcg cgtgaatacg tggaaaaagc tggtatggtt caaatttcag atccagctat
    19381 cttgatccca atcatccacc aagtctttgc cgataacgaa gctgctgttg ccgacttcaa
    19441 gtcaggcaaa cgtaacgccg acaaggcctt tacaggattc cttatgaagg caaccaaagg
    19501 ccaagccaac ccacaagttg cccttaaact acttgcacag gaattggcga agttgaaaga
    19561 aaactagaca gaacaaaacc agccctaagg ttggtttttt cttctctacc aactcccaat
    19621 aactattttg gctttatttc cagagtattt tatggtaaaa tgaagagtaa taatatttat
    19681 taaagaggta aaaacatgat tgaagcaagt aaattaaaag ctggtatgac ctttgaaaca
    19741 gctgacggca aattgattcg cgttttggaa gctagtcacc acaaaccagg taaaggaaac
    19801 acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt ctacatttga cacaagctac
    19861 cgtccagagg aaaaatttga acaagctatt atcgagactg tcccagctca atacttgtac
    19921 aaaatggatg acacagcata cttcatgaat acagaaactt acgaccaata cgaaatccct
    19981 gtagtcaatg ttgaaaacga attgctttac atccttgaaa actctgatgt gaaaatccaa
    20041 ttctacggaa ctgaagtgat cggtgtcacc gttcctacta ctgttgagtt gacagttgct
    20101 gaaactcaac catctatcaa aggtgctact gttacaggtt ctggtaaacc agcaacgatg
    20161 gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag caggacaaaa actcgttatc
    20221 aacactgcag aaggaactta cgtttctcgt gcctaatctc tagaaagagg tcattctatg
    20281 ggaattgaag aacaacttgg cgaaatcgtt atcgccccac gtgtacttga aaaaatcatt
    20341 gctatcgcta ctgcaaaggt agagggggtt cactcttttt caaacagatc agtgtctgat
    20401 accctttcaa aactttcact cggccgtggc atttatctta aaaacgtgga cgaagaactc
    20461 acagcagata tctatctcta ccttgagtac ggagtaaaag ttcctaaggt agcggttgct
    20521 atccagaaag ctgtcaaaga tgccgtccgt aatatggctg atgtagaact cgctgctatc
    20581 aatattcacg ttgcaggtat cgtcccagat aaaacaccaa aaccagaatt gaaagatcta
    20641 tttgacgagg acttcctcaa tgactagtcc actattagaa tctagacgcc aactccgtaa
    20701 atgcgctttt caagctctca tgagccttga gttcggtacg gatgtcgaaa ctgcttgtcg
    20761 tttcgcctat actcatgatc gtgaagatac ggatgtacaa cttccagcct ttttgataga
    20821 cctcgtttct ggtgttcaag ctaaaaagga agaactagat aagcaaatca ctcagcattt
    20881 aaaagcaggt tggaccattg aacgcttaac gctcgtggag agaaacctcc ttcgcttggg
    20941 agtctttgaa atcacttcat ttgacactcc tcagctggtt gctgttaatg aagctatcga
    21001 gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt atcaatggac tgctcagcca
    21061 gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat atctatcaaa cactttttct
    21121 ggctcccact atctaaaaaa atgataatag atataattgt aaacaaaaat ccagataggt
    21181 tttgcatgat tgagaaagtt aaaaaaacta tggcagagaa tcgttaatct cagattgtcg
    21241 gtagaacgat aaacaagggc aaaaaagaaa ccaatcagac tataatataa taaactaatt
    21301 ggatctctgt gagatagtat caaatggcta atcccaaaga tgatagcaga taggataaca
    21361 tccaaatagt acttggacta gggaaagaag gtattcataa aataccctct atcaagagtc
    21421 tcctcaaaaa caggaccgat gattacaggc aggacaaaag ataagatagt cgataaaaag
    21481 gttggttgtc catttgaaaa aagcacggta aaatactcat catgaatatt cctatgatta
    21541 atcaaatgag catagcgtgc ccaaaaatta ccgagaatct gataaaccac ataagttgca
    21601 aataagtaga agacaaatga ccagttccag ctctttttct caaagataaa gagcatcttt
    21661 ttctttttta acctccaaat taatagaagg aaacttccca ctaatcccat tgttaaaata
    21721 agagaataga catcagctcc taaccctaaa atgatcgtca catacaatcc aattgtttgt
    21781 ggtaaatagg tagatagtaa aataataagc aaaaatattc caaattgtct tagttttttt
    21841 gtgtttctca tcgtactttt ttgaaagatt accctgctcg gaagccgtac ttccaagcat
    21901 ctatataaga attaagtgcc ccttgcctca tatagggagc aaattctcta taatataacc
    21961 atctactata tccatcttcc caaacagcaa gaccacctga agtttgctcc aagtcctcag
    22021 ttgaaagaac tgtaaatgta tttgtacctg tcattgcaag taccttctta aaatagattg
    22081 ttgtaggctc acatttatag tatatttctt tttttgtcta ttttatagcc catctcctca
    22141 actggcaatt tttcgacctg aattacattt ttccataaaa aatgagacct ttctagtctc
    22201 atttagtcat tcttagtatt ttctaaatcg ttgatagcgt tcttccagca actcttctag
    22261 cggtttttgt gaaagtctag ccagctccgt ttggagttct tttttgacac tcttaatcag
    22321 ttctttacta gaaagtccta tttcagaaat caccttatcc accacgtcca tttctaacag
    22381 ttcatgcgaa gtgattttca tcagttctgc tgcttccata gcgcgagtac cgtccttcca
    22441 taaaatggaa gcaaagcctt ctggactgag aatggcatag atagaatttt ccagcatcca
    22501 gacacggtcc gcgacagcta gagccagagc cccgcctgaa ccaccttcac cgataataat
    22561 ggagataata ggaactttca ggtcactcat ttccatgaga ttgcgagcga tagcttcccc
    22621 ttgaccacgt tcttccgctc cgacaccagg ataagcacct gctgtattga taaaggtcac
    22681 aactggacgg ccaaatttct cagcctgttt catcaaccgc agtgcctttc ggtagccttc
    22741 tggatgtggt tggccaaaat tccgtttgag gttgtcttgc aaactcttgc ctttttggat
    22801 accaaccact gttacagctt gatctccaag ccaaccaata ccaccaacaa ctgcaccatc
    22861 atcacgaaaa gaacggtcac catgtaattg gataaattca tcaaaaatgc ctgtcgcaaa
    22921 atccaaggtt gtcaagcgac tctgctcacg cgcttctctg actatttttg caatattcat
    22981 ctaggactcc ctccatgcaa tctgactagg ctagcaatcg tatctggtaa gtctcttctt
    23041 ttgacaatag catccacaaa gccatgttct aataggaatt ctgccttttg gaaatcctca
    23101 ggcaagcttt cacgaaccgt attttcaatc acacgacgcc cagcaaaacc aaccaagctc
    23161 tgtggttcag ccagaatgat atcgccttcc atagcgaaag aagctgtcac accaccagtc
    23221 gttggatctg tcaaaatggt caggtaaaag agaccagcat ttgaatgacg tttaaccgcc
    23281 gcagagatct tagccatctg catgagactc atgattcctt cctgcatacg ggctccacca
    23341 gaggctgtga ataggacaac tggcaatttt tcgacagtcg catactcaaa caaacgagtg
    23401 attttttcac ctacaaccgt acccatagaa gccatgataa agttagaatc cataatccca
    23461 agagccacag tctgaccttt aataagagca gttcctgtca caacggcttc atgcagacct
    23521 gttttttcac gcatagatgc cagtttcttt tggtaaccag ggaaatgcaa gggatccttg
    23581 ctttcaatcc ctgtaaacaa ttctttgaag gttcccatat caatcgtcaa agccaagcgt
    23641 tcttgggcag aaatacgaaa ggtatagcta cagtgcggac agatacgttc acttcccaga
    23701 tccttctgat agatggtatg cttacagcct ggacactggg aaaataattc atctggaacc
    23761 tctggcttag cttgaggttt ttccctaact gaacgattgg gattgattcg aatatactta
    23821 tcttttttac taaatagagc cattgattcc ccttttcggt ttaaactctt aaagtcattt
    23881 tattcttttt cttgatattt aggtaagaag gtttccatca agaaggaagt atcataatcc
    23941 ccagcaatga cattgcgatc tgaaatgagg tcaagctgga aatctgcatt ggtctgcact
    24001 ccttcaatct ctaattcata gagggcacgt tgcattttca tcaaggcgtc aaaacgattt
    24061 tcgccgtgta ctatgatttt ggcaatcata ctatcataat aaggcggaat ggtataacct
    24121 ggataaactg ctgaatccac gcgcaagcca actccaccac ttggcagata gagattagta
    24181 atcttacctg gacttggagc aaagttaaag gctgggtttt ctgcattgat acgacactcg
    24241 atggcatgac cgcgtaggac aatatcttct tgcttaacag acaaaggctg acctgccgca
    24301 atgcaaatct gttccttaac gatatcaaca cctgaaacaa actctgttac tggatgttct
    24361 acctgaacac gagtattcat ctccatgaaa tagaaattgc tacttgcttc atcaagaaga
    24421 aattcaatgg ttcctgcatt ctcatagcca acaaactctg ccgctcgaac agcagcagca
    24481 cctatttcat gacgcagcgt ttttccgatt gcaatcgagg gactttcttc caaaaccttt
    24541 tggttattcc tttgaagaga acaatcccgt tcacccaagt gaatcacatg tccatgctca
    24601 tcacctagga tttgaacctc aatgtgccga gctggataga taacccgttc tatgtacatg
    24661 gcaccattgc cataattggc cttggcctca ctagaggcag tttcaaaggc agaaacgagg
    24721 tcatctggtt tttcaacctt acgaatccct ttaccacctc cacctgctga agccttgagc
    24781 ataacaggat agccaatttt ttcagcaaca atcaaagctt cttcagagtt atgcacttct
    24841 ccatctgaac ctggtataac aggcacacct gctttaatca tctgagcacg cgcattgatc
    24901 ttatccccca tcatatccat aacatgacca gatggaccga taaacttgat acctacttct
    24961 tcacacatgg tcgcaaattt ggaattttca ctgagaaatc caaaaccagg gtgaatagct
    25021 tctgcctcag tcaagactgc agctgataga actgcattaa tattgagata agactctgtt
    25081 gccttgccag gaccaataca aactgcttca tctgccaaaa gcgtatgaag agcttcctta
    25141 tcagcagttg aataaaccgc taccgtcgca atccccaatt cacgtgccgc acggataata
    25201 cgaaccgcaa tttcaccacg attggcaatt aaaatttttc gaaacatgga gaacctcctt
    25261 agttcccaat tgcaaaagta aggataccac tggctgcaag cttgccatcc acttcagcct
    25321 ttgcttcaac cacagctatg gtgccacgac gttttacaaa agtcgctgtc ataaccaatt
    25381 ggtcgcctgg tacaacttgc ttcttgaact taaccttgtc cataccagcg taaaagacca
    25441 gttttccttt attttcaggt tttgataact ccaacacacc agcagtttgc gccaaggctt
    25501 ccataatcag aacacctggc ataactgggt attgaggaaa gtggccgtta aagaaaggct
    25561 cgttgatggt cacatttttg atagcaacaa tggtattctc gctcacttcc aagacacggt
    25621 ccactagaag cataggataa cggtggggaa gggcttcttt gattccttga atatcgatca
    25681 tttgatacgt accaatcctt tgccaaactc aaccatttcc tcgttagaga cgagaatttc
    25741 cgttaccaca ccatccttag gagctgggat ttcattcatg actttcatgg cttcgataat
    25801 taccaatgtt tgaccttttt tgacactatc accaactgta acgaaggcag gtttatctgg
    25861 tccagcagcc aagtaaacca ctccaacaag tggactctct acaagatttc cctcagtagc
    25921 cacacttgct tctgctggag ctggaacttc ttctgctaca gtctctgctg gagcagatgt
    25981 aggagctact ggactcggtg ttgctagaac gggtgctgga gcgacttgag ttgcaacttc
    26041 aggcacaggt ctcgcttcat tcttgctaaa ctgcaactca tccgtcccat ttttataaga
    26101 aaattctctc aaacttgact ggtcaaattg agtcatcaag tctttaatat cgtttaaatt
    26161 catacttatc tattctccca acgtttgaaa gcaagaactg cattgtggcc tccaaaacca
    26221 aaagtatttg aaatagcgta tggaatttct ttctccaagc cttgtccata aacgacatta
    26281 acttcgatat aatctgatac ttcacttgtc ccagctgtca ttggtacaaa gttatgacgc
    26341 atagcttcga tggtgacgat agcttctact gcacccgcag cccccagcaa atgtcctgta
    26401 aaagacttgg ttgatgatac aggtacttcc ttaccaagaa cagctacgat agctccactt
    26461 tctccttttt cattggcagg agttgacgtt ccgtgagcat tgacataggc tacttgctct
    26521 ggagaaatct cagcttcttc caaggctagt ttgatggcct tgatagctcc ctgaccttct
    26581 ggatgtggag aagtcatgtg gtaggcatca caagtatttc cgtaaccaac cacttcagcc
    26641 aggatagtag ctccacgttt ttcagcgtgt tcaagacttt ctagaaccaa catccctgaa
    26701 ccttcaccca taacaaaccc attgcgatcc ttatcaaatg ggatcgaagc acgagttgga
    26761 tcctctgtag tagagagagc tgttaaggct tggaaaccag cgatggcaaa aggtgtgata
    26821 gaagcttctg ttcctcccac caacatcaca tcttggaaac caaacttaat ggagcggaag
    26881 gcatccccaa tcgcatcatt tgatgaagag caggcagtat tgatagattt acaaacaccg
    26941 tttgcaccaa aacgcatggc tacattccca gaagccatat ttggtaaagc ttttggaaga
    27001 gtcattggtt tgacacgttt gggtcctttt tcatgaaggc gaagtacctg atcttcaatt
    27061 tccttgattc caccaatacc agatgcaacg ataacaccaa aacgatccct attaagagcc
    27121 tctacatcaa gattggcatg atttacagcc tcttgggctg catacaaggc atataaagaa
    27181 tagttatcaa aacggttggt atcttttttt acaaagtatt tatcgaacgg aaaatcttgg
    27241 atttctgccg cattatgcac atcaaagtca ctatgatcaa attttgtaat gccaccaatg
    27301 ccgattttcc cagttgctaa actattccaa aattcttctg gtgtatttcc gattggagat
    27361 gttactccat aacctgttac cactactcga tttagtttca ttcttttcac ctctagcttt
    27421 cgctacatac ttaagccacc atcaatggca accacttgac cagttagata atcttggcct
    27481 gctaaaaata ctgtcaaatc tgcaacctgc tctgcctgcc caaattcttt catcggaatc
    27541 tgagctagtg tagcttcctt aatcttatct gataagatag ctgtcatatc agactcaatc
    27601 attcctggag caatcacatt gactcgtata ttccgactag cgacctcgcg tgccacagac
    27661 ttggtaaagc caatcaagcc agccttagaa gcagcatagt tagcttgacc aatattcccc
    27721 atcaaaccaa caacactaga catattaatg atagcacctt ctctggcttt catcatcggt
    27781 ttcaagactg attgtgtcat attaaaggca ccagtcagat tgaccttgag cactttttca
    27841 aaatctgctt ctgtcatctt gagcataaga gtatcttggg taatccctgc attgttgacc
    27901 aaaacatcta ctgaacccag ttctgcaata gcttgatcaa tcatacgctt agcgtctgca
    27961 aaatctgata catctcctga aatgggaacc accttgatac catagtttga aaactcagcg
    28021 agcaattctt ctgagattgc cccacgactg tttaagacaa tgttggctcc tgcttgagca
    28081 aacttgtggg cgatggcaag accaattcca cgactcgaac ctgtaataaa gatattttta
    28141 tgttctagtt tcattttttt cctttcaaaa cttctactta ttttagtcta tttttctaaa
    28201 agtgctacta aactcgcttg atcttccaca tgagctaagt gagcagtttg atcaattttt
    28261 ttaacaaaac ctgacaagac tttccccggt ccaatctcga taaagttgct tatgcctgct
    28321 tcttgcatga ccccaatact ttcatagaaa cgaacgggtt ccttgacctg acgcgtcaag
    28381 agctgagcaa tgtcctcttt ttgcatcaca gcagcttctg tattgccgac taggggacaa
    28441 gtaaaatttg aaaaacttac ctgagctaga gtttcagcta gtttctggct agcaggctca
    28501 aggagagcgg tgtgaaaggg acctgacacc ttaagaggaa tcaagcgttt ggcacctgct
    28561 tcttgcaaaa gttcaaccgc tcgatcaact gcaaccactt ctccagcaat gacgatttgt
    28621 gcaggtgtgt tatagttggc tggagtaacc actccaagtt cagaagcttt ttgacaggct
    28681 tcttcaatga cctctactgg cgtattgaga actgctacca tcttgccaga gtcagcagga
    28741 gccgcttctt ccatataggc tccacgctta gctaccaagg caaccgcatc ttcaaaatcc
    28801 aaggcgccgc ttgccaccaa ggcagagtat tctccaagag acaaaccagc aaccatatca
    28861 ggctgatagc ccttttcttg caataaacgg tagatagcaa ccgaagtcgc tagaatggct
    28921 ggttgcgtat agcgggtctg attgagtttg tcttcttccg tatcgatgag ataacgtaaa
    28981 tcataaccga gcacctgact cgctcgatca atcgtttctt tgacaatcgg atactgatca
    29041 tagaaatccc gtcccatccc tagatactgg gcaccttgac cagcaaataa aaaggctgtt
    29101 ttagtcattt cttacaactc ctgcccagcg agaggcttct tcttgaattt tcttagcggc
    29161 tccgtaatac aaatctttta ggatttcttc agctgtttct tctttagaaa caagccctgc
    29221 gatttgacct gccatgacag agccaccatc cacatcaccg tgaacaactg ctttggctag
    29281 ggcacctgct cccatttgtt caaagatttc taaatcagga tcttcctgct taaaggcatc
    29341 tttttcagcc agttcaaaat ctctagtcaa ctgattttta atagcacgaa cagcatgacc
    29401 aaagtgctga gctgaaatcg tagtatcaat atcccttgct tttaaaattt tctccttgta
    29461 gtttggatgg gcattcgact cttttgcaac tacaaaccgt gtccccacct gtacagcctc
    29521 tgcacctagc ataaagccag ccgcagcacc ttcaccatcc gcaattcctc ctgcagcaat
    29581 aacaggaata gatatagctg tggctacctg tcgcaccaag gtcatggttg ttaatttacc
    29641 gatatgcccc ccagcttcca ttccttctgc aataacagcg tctgcaccga ttttttccat
    29701 gcgtttagct aaagcgacac taggaacaac aggaataacg attatcccag cttcatggaa
    29761 acgttccata tacttgcttg gatttcctgc tcctgttgtg acaactttaa caccttcttc
    29821 aataacgaga tccacgatat cttccacaaa gggagataag agcatgatgt tgaccccaaa
    29881 gggtttatca gtcaatgatt tgattttatc aatattggcc ttgacaactt ctttcggggc
    29941 atttccccca ccgataattc ctaatcctcc agccttggaa acagcccctg ccaaatcacc
    30001 atcagcaacc caggccatcc ctccttggaa aataggatag tcaatcttca ataattctgt
    30061 aatacgcgtt ttcatagtgc ctccaacctt ccttgcttac gtaatagttc gatttcacca
    30121 taatttgaca gtcaaactat tacctaaaca agagggagtg ggtttctccc tactccttct
    30181 actaatattc tgcttatttt gcttgctctt caacgtaagc aaccaagtca ccaactgttt
    30241 tcaagtcatt ttctgcttcg atttggatat caaaagcatc ttcgatttct gagattactt
    30301 ggaacaagtc caatgaatct gcgtccaaat catcaaaagt tgattcaagt gttacttctg
    30361 atgcgtcttt tccaagttct tcaacgataa tttcttgtac tttttcaaat actgccatga
    30421 taggactcct ttaaaataaa tagttttttt ataacaatgt gttcaccaca tgattaccta
    30481 aattgtaaga atgagcgtgc cccaggtcaa gcctccaccg aagcctgata gaagaacagt
    30541 ctggctacca tctaaaggga tgagaccttg ttctacacac tctgaaagta aaatcgggat
    30601 actggctgca ctggtattgc catattccat catattggct ggaagtttgg ctcggtcaac
    30661 accaattttt ctagccatct tatccaaaat acggtcattg gcttgatgaa gtagcagata
    30721 atccaagtct gtcacctcta taggagattc atcaatagtc tgcttgatag acttggctac
    30781 atctcgaatg gcaaaatcaa agactgtgcg tccatccatc ttcaaaaacg aatctgcact
    30841 ttcttgatct gaaaatggag aatgcaaacc tgaatgccca taagttaaac actcgctgcg
    30901 acttccatcg ctattgagac tctcagctaa gaaatgctct tgctcgctag cttctaacaa
    30961 gacaccacca gcaccatctc caaacaacac agctgttgat cgatccgacc aatcgactgc
    31021 cttagagagg gtttcactac caatcaccaa gcctttttga aagcgaccag aagcgataaa
    31081 cttttcagca gttgaaagag caaatacaaa tccactgcaa gccgcggtta agtcaaaagc
    31141 aaaggcttta ttagcgccaa tattagcttg aacacgagca gctgtagagg gcatcatcga
    31201 atctggagta atggtagcta ggatgataaa atccagttct tttcctgtta ttccagcttt
    31261 tgccatcagt ttcttagcaa cctctgtagc caaatcactg gtagattctg ttcttgaaat
    31321 atgcctttgt cgtattcccg ttcgacttga aatccactca tcattggtat ccataatctg
    31381 agccaagtcg tgatttgtaa ccacttgctc tggcacataa tgagcaacct gacttatttt
    31441 tgcaaaagcc attatttcaa atcctccaaa aattggtaaa gattagtcaa gcctttaccc
    31501 atgacagcaa tttcttcctc gctcatgcca tcaataattt tttctaccat ggccttgtgg
    31561 aagcgtttat gcagtctatg aatcaagcga cccttctttg tcaaatgcag atgcaccaca
    31621 cgacgatcct gttctgaccg aactcgctca atgtagccct tacgctctaa attgttcaaa
    31681 cttgtcgtaa cagttccaag agttaccatc aactcttttg acacttgact tggagtcaca
    31741 tctggagcct taccgatgac atcaatcgta tgcatttctt tgatggagat atccttaaaa
    31801 cgactacctc tcaagttcac ttcctcaatt acaaggacat tgttaaatat agatgttaaa
    31861 tattcattga ttcgttggta gtccattttt catatccctc cttcttcaaa aaacttttac
    31921 aatcaaaaca tttgacagaa agaattatat caaaattcaa agaatgatgc aagtattttt
    31981 tattttcctg taaatttagg tcttcttctc tccgaatgag ctcgcactcc ttctttgaaa
    32041 tcctctgttt gagctaagga tttctgtagg ttcagttcta aagtagcgta accctgccag
    32101 tctttaaatt ggctctccca aaccaacttc ttaatggcag cataggaatt acttgaagca
    32161 cgtcttaatt ttttaagaag ctgttctctc gtcttttcaa gtttttcagc ttcagaaacg
    32221 cggtaaacca acccccattc tagggctttt tctgccgtta aagcctctcc tgtcatagct
    32281 aattgagcag cacgcgtcac accgatactg cggctcaaga gatgaattcc ccctgcatct
    32341 ggagccaaac caacaccaac aaaggcttgg ataaacttag ccttatccgt cgccaaacag
    32401 aaatctgccg caacagccat attcgctgcg gcacctgcaa cagcaccgtc aacttccatt
    32461 aaaacaggtt tggctatttg cttgatttta taagaaatcg tattgaccaa ctctgcgatt
    32521 tttgtcaatg atggaatatc atcctcatcc actgcccgct tcatctctac caaatctccc
    32581 ccaactgaga agacctttcc attggcattg attaagataa aatgcacagc tggattttct
    32641 tctgccaaag tcagagcttc taaaatctcc tcacacatgg gaatatgaaa accatttgcg
    32701 acctcaggac ggttcaaggt aaggattgcc aagtcctctt caagctgata aataatgtgt
    32761 tccatcaggg ctccttttta ttttataagc agtttatact cttcgaaaat ctcttcaaac
    32821 cgcgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat
    32881 ttacaacctc aaagcagtgc tttgagcagt ctgcggctag cttcctagtt tgctctttga
    32941 ttttcattga gtgttaaatt atttcactgt caaagtatat cttttttagg agcagaaagc
    33001 aagaaaaaat cgactgaaag tgtctcagcc gataagaaag gctcgcttta ggctagaacg
    33061 catcttattt tcttcattga aaaaagcctt tctttctgct ataatcgtat aaaatactta
    33121 ctttaggagt tcttatgaaa gttgttaaat ttggaggtag ttctcttgcc tctgctagtc
    33181 aattagaaaa agttttaaac atcgtcaaaa gcgattcaga gcgtcgtttt gtagtcgttt
    33241 ctgcgcctgg taaacgcaat gctgaagata ctaaggttac ggatgccctg attaaatact
    33301 accgcgacta tgttgcgggt aacgatatta gcaagagcca aagctggatt atcgaccgct
    33361 atgctgctat ggttagtgaa ttgggactaa aaccagctgt gctagaaaaa atttctaaaa
    33421 gcattcacgc cttggccact cttcctattg aagaaaatga atttctctac gatactttcc
    33481 tagcagccgg tgaaaataac aatgccaaat tgattgctgc ctactttaac caaaatggta
    33541 tcgatgcacg ctatatgcac cctagagaag ctgggattgt ggtcacaagt gaacctggtc
    33601 acgctcgcat cattccatca agttatgaca agattgaaga attgacaaac accaatgaag
    33661 tccttgtcat tcctggtttc tttggtgtca ctaaggaaaa tcaaatctgt actttctcac
    33721 gtggaggttc tgatattaca ggttctatca ttgctgctgg tgtcaaagcc gacctctatg
    33781 aaaactttac ggacgttgat ggtatctttg cagcccaccc tggtattatc caccaaccac
    33841 actcgattcc tgagttgacc taccgtgaaa tgcgcgagtt ggcctatgca ggcttctcag
    33901 tccttcatga cgaggctctt cttcctgcct accgtggaaa aattcctctg gttatcaaga
    33961 ataccaacaa ccctgaccat ccaggtactc gtatcgttct aaaacacagt aatgatgaat
    34021 ttccagttgt gggaattgct ggtgactcag gctttgtcag tattaacatg tcgaaatacc
    34081 tcatgaaccg tgaggttgga tttggccgca aggttctgca aatcctggaa gaacttaaca
    34141 tcggttggga acatatgcca acaggtatcg acgatctttc tatcattctc cgttctcgcc
    34201 aactaactcc catcaaggaa gaagaaatcc tgcgtcagtt ggttcaaaag gctaaagtag
    34261 atcatgcaga aatcgaacac gacctttcta tcattatgat tgttggtgaa aaaatgaaga
    34321 gccacatcgg agtgactgct actgcgacac gcgctctatc tgaaaacaaa atcaacatcc
    34381 agatgatgtc tcaaggttct agtgaagttt ctattatgtt tgttgtcaat aaagaccaag
    34441 agaaagcagc aattaaagcc ctctacaatg ccttttttgg agaaagtaag gaagactaag
    34501 catggctcaa tcacttaaca aaacagtact cctcagtacg acaggcactt cctacctctc
    34561 tatcgctggg aaagttggga aattccttgt cggagatcag gctttggaat tttacccaga
    34621 tgtcaatgtc gaacaattta tccagattcc ttggagccat atcaatcaga ttggagccaa
    34681 tgtcactgga tgcaaaatca gccgccactt cgaagtcttt acagacaaag gaaaattcct
    34741 ctttgcttca aaagactcag gtgccattct caaaattgca cgcgaaaaac taggcaatga
    34801 caaggtcgtc aaacttccga ccctgattca gacaattagc caaaaattta aaaatctatt
    34861 tgcaaaaaag tagaaacttt agtataatca tagcaacgga taagtaggtt atcttcttct
    34921 ttcagaaagt ctgcgggtac tgcgagcaga taggagggat aggtgaaatt ctaccgttag
    34981 taacaattac atacacaatc aagtgcacac ctgtgaagtt ggatggaacc gtggccctgc
    35041 cactccaacg ttttgtcagg cgtgcttttt tcataaagga gttcttatgt tagatatcaa
    35101 acgtattcgt acagattttg aagctgtcgc agaaaaatta gctacacgtg gtgtagatgc
    35161 tgctgtcttg aatgaaatga aagaaatcga tgctaaacgt cgtaacatct tggtcaaggt
    35221 tgaaactctc aaagcagaac gtaacacagt ttctgctgag attgcccaag ctaagcgcaa
    35281 caaggaaaat acagatgaca agattgctgc catgcaaaat ctatctgctg aggttaaagc
    35341 cttggatgct gaattggcag aaatcgatgc taaattgaca gaatttacaa cgactcttcc
    35401 aaatatccca gctgacagcg ttcctgttgg ggctgacgaa gacgacaatg tggaagttcg
    35461 ccgttggggt actccacgcg agtttgactt cgaacctaaa gctcactggg atctcggtga
    35521 agaccttggt atccttgact gggaacgcgg tggtaaggta acaggcgctc gcttcctctt
    35581 ttataaaggc ctcggtgctc gtttggaacg tgctatctac aactttatgt tggatgaaca
    35641 tggaaaagaa ggctatactg aagtcatcac accttacata gtcaaccatg attctatgtt
    35701 tggtactggt cagtatccaa aatttaagga agatactttt gaactcagcg ataccaactt
    35761 tgtcttgatt ccaactgctg aagttcctct gacaaactac taccgtgatg aaatcttaga
    35821 cggcaaagat cttccaatct acttcactgc tatgagtccg tcattccgtt ctgaggctgg
    35881 ttctgccggt cgtgatacgc gtggcttgat ccgtttgcac caattccaca aggttgaaat
    35941 ggtcaaattt gccaaaccag aagaatctta cgaagaattg gaaaaaatga cagccaacgc
    36001 tgaaaacatt cttcaaaaac tcaaccttcc ataccgtgtc gttgctctct ctactggaga
    36061 tatgggcttc tcagctacga agacttacga cttggaagtg tggattccag cacaaaacaa
    36121 ttaccgtgaa atctcaagct gttcaaacac agaagatttc caagcccgtc gtgcccaaat
    36181 ccgttaccgt gatgaagcag atggcaaggt gaaactcctt cataccttga acggttctgg
    36241 acttgcagtt ggacgtacag tggctgcaat tcttgaaaat taccaaaatg aagatggttc
    36301 tgtgaccatc ccagaagcac ttcgtccata catgggtgga gctgaagtca tcaaaccata
    36361 aaaaataagg tttagctatt tctagctaga ccttttttcg taaccaaatc agataagcac
    36421 ctagtacaaa gaataaaata gttaggcata taatggtttc agccaatacc aggtaatcca
    36481 gaaatggaag tttcaaaatt ccctgagcca tcttgagcga ggtcgctgtg ataatggttg
    36541 ggaaggtgag ggctgagaag gctggttgaa aaccttgttt taaaatgttg ggcagacgag
    36601 ttaaaacaaa gaaaaagaag gattgagaag ccaaaatcat gacaatcaag acccaagtcg
    36661 gcaggctggt tcctcctact cgaactagag aagccaagag tagagagaaa ggagcacagt
    36721 agattccttc ttgtccaagc aaggctagtg ggagtggatg tttctttaaa tcgctataaa
    36781 taaggggata gagatagaag gtcaagagaa aaccaaaact caaggtcgca taggcaattt
    36841 cgataatacc taccagagga taggtcaagg cagccactgc tatccccaca tagagaaccg
    36901 tccagcttgg agtggcatga accctccgct ctggacaagc aaacttgatg gtaaaaccag
    36961 caatcaaggt caaatccaag agaaatgaaa accaccaaat cccttgtgct accaaaggaa
    37021 gataagagaa tacgcgaaag acataggtcg ataaaatcat cccagccata ggaaaggttg
    37081 ccattcctga caaaagaggg ggcttggtca attcttgctt ggtttctttc caattaaaga
    37141 gatgcagaat tagaaagtaa atccataaaa ccaaaccagt cagactaaaa agatgggata
    37201 gaactggcaa catatctaaa ataagatttc cagctcctgc caaacctagc aaacaacctg
    37261 aaaatactaa ggggagtttt ttcatcctaa cctccaataa tcatgttagt ttcagtataa
    37321 cataaaagcg cttaaatgag gatttaaaaa aacgaagtcc gattatttca gacttcattt
    37381 tactcagata tgaattaggc ataaggttgc aattctggat taattggtgt attagctaag
    37441 ttgttggcat agttacagag gattgctagg ctgacaccga aaaccacatc caaggcattt
    37501 tgttgagtgt agccagcttc taaaaactca gacaaggctt catctcctac acgacccttg
    37561 gtattgataa ctgccaaggt aaacttagct agggtatcca atttaggatc tgtttcaatt
    37621 ggagtactat tgcgaagagc ttgaatcaag tcatcattca tctggatttg tttgatggaa
    37681 aaggctgtgt gacctgcgac acagaaggca caaccattgg tcacggctgc cgtgatttgc
    37741 accacttcac gctcaacggg tgtcaggctg ttgcgacggt ggatagatga gacaatttgg
    37801 taggcttcta aaacagtcgg ggcattggcc aagagaccga ttaggttggg aatatagcca
    37861 ttgttgtctt tttctactgt ttcaagaatt tctttcactt ctgctggtgc tgactctact
    37921 gtatggatag taaatgttgt cataagatac ctcttttctt attattgaca ctaatattat
    37981 tggaaaatct tataaaatcc tgattcctaa gtttatctaa gataaagctt tattctctca
    38041 taagattttc gttgttatat tagtttatca cacttccaat cacttgcata atatatatta
    38101 tatatcaggc tgataaaaat tatttatagg caaaaaaatc acacgagctg tgtgattcca
    38161 ttatttgtca aaatactttt tagtttcagc aataacgact ggcgacaaga ccaagagggc
    38221 aatcaagttt ggcagagcca tcaaggcgtt aacgatatct gcgataatcc agaccatatc
    38281 caactcgata aatcctccta acaagaccat gagcacaaaa accacacggt agagccagat
    38341 aaagcgaacc ccaaagagga actcaaaaca gcgttctccg taatagttcc aacctagaat
    38401 cgttgtaaag gcaaaaagta caaggaagat ggtcaagagg gcaggcccaa agtgtgaaaa
    38461 gactgttgag aaagctgact gagtcaaggc aaccccattc aagtcaccac tccaaactcc
    38521 agttaccaag atggtcaaac cagttagagt acaaatgatg agggtatcaa taaaggttcc
    38581 tgtcatggaa atcaaacctt gctctactgg ttcatttgtc ttggcagctg cagctgcaat
    38641 aggagcagaa cccagaccag attcgtttga gaacacacca cgcgccacac cattttgaat
    38701 agccatccga acgctagcac cagcaaatcc acctaccgca gcaaggggac taaaagctga
    38761 ggtaaagact aaagcgattg tgccagggat ttttccgata ttaaagaaaa taactataag
    38821 agttcctaag atataaatga tggtcataaa aggaacaaca gtagttgaaa ccttagaaat
    38881 agacttgagt ccaccaaaga ctgcaatcgc tacaaagaca gacaagacga gagctgtgat
    38941 gactggcgaa atcgtcgttg tattttggat agattctgta atcgagttga cttgggtgaa
    39001 ggttccgatt cccaagagag caaccaatac tcctgctact gcaaacaaaa cagcaagtgg
    39061 tcgccacttt tctcccatcc ctagaaggat atagtgcatg ggacctcccg ctactgcacc
    39121 atggtcgtcc ttggtgcggt atttgatggc caagagtcct tccgcatgct tggtagccat
    39181 tccaaagaaa gccgccatcc acatccaaaa tagagctcct ggtccaccaa ccttgatagc
    39241 cgtcgcaact cctatgatat ttcctgttcc aacagttgat gccaaggctg tacacagagc
    39301 tgcaaaactg gatacatcac catgtccctt atcctggata aaaataagct gaaaggcctt
    39361 gggcagacgc aaaacctgca agagtcctag ccgcatggtt aggtaaatcc ctgttccgac
    39421 caataaaatc aagaggggcg gtccccaagc aaaatcatcg attgatttaa gcaattctaa
    39481 catttccttc tcctatcgtt tcaaccccaa aagaaagagc acatgcaaga tacatgtact
    39541 ctggaatgct tagataaatg ctaaaaagcg gtctatccta gctctgtcct tttacctgag
    39601 agtttgagca gttgcctgcc ttgccccttc ggtgccttta cggtctctcc agagttccgt
    39661 ccatttacag tcatggaaaa tcaaacgatt ccccacttct attaaacttc attcggtgtt
    39721 ggtatttaat tgattctaat tttacaaaaa atgttggctt ttgtcaatgt gtttattagt
    39781 aaaaattagt tcaacagttt ttactttata aagtccagaa tactgctatc ctttaaaagt
    39841 gacaatagtc gcaccactgc ctccagcatt ttgtggggca tagccgaaac tcttgacatg
    39901 tttgtttctt tgcaagtatt tggtaactcc ttcacggatg actcctgttc cgataccatg
    39961 gatgatatca acttgagcca tattgttaag caaggcttgg tcgatgaagg tatctagctc
    40021 attcatggct tcttcatagc gcttgcctcg aagatccagt ctagcttgag gtcctcgccc
    40081 agaagttcgt ttcacaacat tgacctgttt cttcttgact ggtttttctt gctgggcttg
    40141 aacaagatca aactctttct cttccaaggt catcttaatc aagccaactt gggcttccca
    40201 gcggccgtcc ttgagttgac tggtcaaggt accacgctga ccataactga gaaccacgat
    40261 atcatctccc acctttggag ctcgtttttt cttggccttt tgaaggacct tgtttttaga
    40321 caagtccact ttttcaggag ccaatttttt caacttggcc ttggcttcaa tgatttcgtg
    40381 gggcttgagt tgggatttac tgtggagatt tttgagaatc tggtcacttt cacttagggc
    40441 catatccaca atctcagcag cctgttcacg cgccttgtta agctcggttt ccttttcacg
    40501 attaagctcg ttgtagagtt tttttagcgc acggttcatc ttgagatttt cttgctccac
    40561 ctcacggata ttgtccaaac gtttgcggct ttccagcgtc tgctcttcta attgctcaat
    40621 gatacgattg acgtcattgt cctgatcgat ctgctgactg gcatctccta cgataacttc
    40681 agataggcct agacgtttgg caatttcaaa ggcattactt cggccaggaa caccctgcat
    40741 aaagcgatag gttgggcgaa gagttgcagt atcaaactcc atactggcat tttgcacaaa
    40801 ggctgtctca ataccgtagg ccttgagttc tggatagtgg gtcgtcgcca tggtcttgat
    40861 ttgacgcagg cgaaggtcct ccagaatagc catggcaagg gctgctccct cttggggatc
    40921 agtaccagcc cccaactcat ccaaaagtaa gagtgaatgt tggttgacct tgccaagaat
    40981 atccacgata ttggtcatat ggctagagaa ggtagacaag ctctgctcaa tagactgctc
    41041 atctccaata tcagcaaaga tttcttcaaa aataccaaca cgacttccct tgtctgctaa
    41101 aatcggcaat cctgactggg ccatgacctg tgtcaagccc agagttttga gcatgatggt
    41161 cttcccacct gtattgggac ctgtaatgac aatagctgtt aaatcttgac caaaatagac
    41221 atcatttgcg acggcatttt tgaccaaagg atggcagaca tggagcagtt gaatctcttg
    41281 attttctgac agctgaggca cgactgcttg tctttcttgg ataaatcgaa ccttggcacg
    41341 aatcaagtcc agatgaccga taatccaagc gtcattagca atctcagccg catgagggcg
    41401 gacacgctca gaaatttctt ggagaatgcg aagcatttca tagcgctcat ctgctcgcag
    41461 actagcaatt tcttcgctca gtttgactac ctcacgtggt tcgatataga cggtgtttcc
    41521 actagcagaa atatcatgaa cgacacctgc aatcttattg cggtaggtgt ttttgactgg
    41581 taaaacctga cggccatttc tgctagcaac aattccttcc gtcaacatct gcgctttttg
    41641 cttgagtaag tcttgtaaaa catcgcgcac ctgactctcg ctatcatgta tttttcgacg
    41701 gattcgcgcc aattcttcac tggcaaaatt ttcaatgaaa cccgcatcat taaaggcctg
    41761 aagatttcct tgtaattgcg gaaaatcatg taatttctca aaccaaaggg ctaattcttc
    41821 caagctgaca ttttccagat tggcgtaaaa attttgaagt tctcggctgg caagaagcac
    41881 gcgtttcaag agtaggaact cctcgatatt gagatccgct cccatctcca acctcttgca
    41941 gactcctgca atttccttag ttgagagaat agtaaaatgc ggttgctcga cgaaaagagc
    42001 ctgcatttct ttcatctcag caaaagcctg tttgatttta tctgctttgg cagtcggagc
    42061 cagctgtctc aattgctcca agccctgctc ggtcaacaaa tgaggctcaa acaaggcctt
    42121 gaccttatcg aactctaatg tttctaatat tttcttattc atctttattt ccttgtcttt
    42181 gaatgtctag gtgtggtagc tttttacatt ctgatagatt cgagtcaaat ctgtaaacaa
    42241 agggctagga aaactcctgc cctttttatc cgattaaatt tgtcacccag atttgtttga
    42301 gccaactggt tgttatcggt atgctctgga tgatgtgttt tgcgacgata ctcttttcaa
    42361 gaggattttg tataactgcc atggggatgg tcgccaagat tgtcaaggcc atttgcaaga
    42421 caaataaggt caccaacatg gacaagatac ctgctgaaac ttggaacaac ttaccaccca
    42481 gttttttgct aggaatcaag tgtaagagaa gaccaagcaa acgaccaata ctatagacaa
    42541 tcccaaatac aagcaagtag ccgatacctg cataaaagac cttatccagc tgaaagagtt
    42601 gatccgatgg gaaaaagaaa gtcccctgac cttcctgcga atttgcataa gggagcaata
    42661 aatggaattg ctctccaagc cccttataaa actggccagc cataaaagcc gatgccatgg
    42721 ctgaaatcag gtaataaacc tgtaagagca ggcctctccg atagccgata taaaatcccc
    42781 aaaccaagac caatagaaga aggaatgaaa tcataaggaa tcctcaatct tgctctgttc
    42841 ttgcttacaa gtcacaagct tgtgacggag ttcttctagc tcttgctcct tatcgtcaaa
    42901 ttcaatctca cggctgagct gagttgataa acagttgact gccaacaaaa gagcgattgt
    42961 ttcatcatct gcgctaggca tttgttcttt aattgcttgg tatttttctg tcgcaacctt
    43021 agcgatttcc tccataaaaa ggttatcatg ttcgcttgtc aaggttaacg tttttttccc
    43081 gaatgtaaat ttgaatcgat ttagatttgc cataaaattc acctcacgat attataccaa
    43141 aattcgctaa ttttgtcagt ttttacaaat tttactgctt ttgtggtaca atagaaacta
    43201 tggcaagtat cacactcaca ccaagcgaaa aggatattca ggcttttctt gaacactatc
    43261 aaaccagtct ggctcctagc aagaatccct atatccgcta ctttttgaaa ctacctcaag
    43321 caacggtttc tatctatact tctggaaaaa tcttgcttca gggtgaaggg gctgaaaaat
    43381 acgccagttt ctttggctat caagctgtag agcaaaccag cggacaaaat cttcctttaa
    43441 ttgggacaga tgaggtggga aatggttcct actttggtgg gcttgcagtt gtggctgcct
    43501 ttgtcacacc tgaccagcac gactttttac gaaaactcgg tgtgggggat tctaagactc
    43561 tgaccgacca aaagatccgt cagattactc ctattctcaa ggaaaaaatt cagcaccagg
    43621 cactccttct ctcacccagc aagtacaacg aggtcatcgg agaccgctac aacgctgttt
    43681 cggttaaggt tgccctccat aatcaggcta tctatctcct ccttcaaaaa ggtgttcagc
    43741 ctgagaaaat tgtgattgat gcctttacca gtgctaaaaa ttatgacaag tacttggcac
    43801 aagaggccaa tcgtttcagc aatcctatca gcttagaaga aaaggctgag ggcaaatact
    43861 tgtctgtcgc agtttcttct gtcattgcgc gtgatctctt tctggaaaat cttgaaaatt
    43921 tgggacgaga actgggttat cagctcccaa gtggagctgg aacggcttct gacaaggtgg
    43981 ctagccagat tttgcaagcc tatggtatgc agggactcag cttctgcgcc aaattgcact
    44041 ttaaaaacac tgaaaaagcg aaaaaacgct tagaaaggta agttatgaat tcatttaaaa
    44101 atttcttaaa agagtgggga ttgttcctcc taattctgtc attactagct ttaagtcgta
    44161 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
    44221 gcgaaattct cttcgttgta aaacaccttc ctattgaccg ttttgatatc gtggtggccc
    44281 atgaggaaga tggcaataag gacatcgtca agcgcgtgat tggaatgcct ggcgacacca
    44341 ttcgttacga aaatgataaa ctctacatca atgacaaaga aacggacgag ccttatctag
    44401 cagactatat caaacgcttc aaggatgaca aactccaaag cacttactca ggcaagggct
    44461 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagcccaa gccttcacag
    44521 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
    44581 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
    44641 atatcacagg ggaagctaaa ttccgcttct ggccaatcac ccgtatcgga acattttaag
    44701 aaacctaaga ggccgagaat caccaatctc agcctcttct tctatcgtga gaaaatgatt
    44761 ggtaactatc taaacttacc agaacagaaa cacctcaact ctcacctatt catgcaaagg
    44821 aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga aaatcccagc
    44881 aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga ttttgatgat
    44941 tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga ctatactttt
    45001 tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag tcgttatgat
    45061 cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca tttcaagggg
    45121 attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa
    45181 attttgcaac acccagaaaa gttagaaggc atcacaggac tctctgccaa aaatcgcgag
    45241 gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttgtc caaactagcc
    45301 aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa ggaagaaacc
    45361 cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg tttgggcttt
    45421 accattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc
    45481 cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga cacctatgtt
    45541 gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg tcccgtggaa
    45601 ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga caaggttcag
    45661 cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg catccgcagt
    45721 cacttggttc gtatccttga aaaaggaaaa cagaagagtc atgatttaga aaccattcaa
    45781 aaacatatca ctactatcga ggaagagctg ggaattgagt atgataacat tcaaaaacag
    45841 gctatctgtg atgctatcca gaataaggtc tttatcctga caggtgggcc tggtactggt
    45901 aagacaactg ttatcaatgg aatcattgct gtttatgccc ttttagaagg acttgacttc
    45961 aggaagaaaa gcaatctgcc cattcttctt gctgctccaa ctggtcgagc tgctcgtcgc
    46021 atgaatgaat tgacaggttt gcctagcgcg accatacatc gccacttggg aatgacaggt
    46081 gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat cgtggatgaa
    46141 ttctctatgg tagatacttg gctggccaat caactcttct ccaatatctc ttctaacagt
    46201 aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg acaggttcta
    46261 gcggatctac ttcatattcc tttgattcct cagactcgct tggaaaaaat ttatcgacaa
    46321 agcaaagaat caaccatcgt caccctagct agtcagattc gacagggcat cttgccagct
    46381 gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg ccatattcct
    46441 gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg gtattcccgc ccgtgatatc
    46501 caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa tcagctcatg
    46561 caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc tcagtgtcac
    46621 tatcgtaaga gagacagggt cattcatttg gttaacgatg ctgaaatcaa tgtctttaat
    46681 ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc gaaacaagac
    46741 gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga atggtacaag
    46801 attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt cccagttgtc
    46861 atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat ctacacagcc
    46921 attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt cgactatgct
    46981 acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag tgatctactg
    47041 gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag tgcctctgaa
    47101 caatcctaca tcctaaccga agaaaactgg gaccgcatcc cagccatgat tgggattaca
    47161 gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaacccac caattcaggt
    47221 gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa ttcaacagct
    47281 tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg aacttgtgca
    47341 acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc ttcttctgaa
    47401 gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt agtacgtgac
    47461 tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt gatttggaag
    47521 tacatgtcag ggttgatccc ttgacgttgc aaattcccaa ggaattcatt tactgaacgg
    47581 tgaacttctt catggatcat ttcttctgga agttctacga tttcagcatt ttctacagct
    47641 gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc agcagccaat
    47701 tctttgctgt atttttcttt caagtcagca agtgtttcaa cttcttcatc aatgtctttt
    47761 gcaagttcat cgtcaagagc cggaacttct ttagctttta cttcgtggat agttgtcacg
    47821 aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa tgttacgata
    47881 acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc agggatgaat
    47941 tgacctgaac caagtccaag tgagaagttt tcaccttttc caccgtcaaa ttcaacaccg
    48001 tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc agcttccttg
    48061 ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcgac atcagcgtca
    48121 gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc caattttact
    48181 tcaggttttg taacgacttc agcagtgata acccagtctt gacctttttc cattgaagtt
    48241 acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc tgcttcataa
    48301 gcgtttggca aaagtgcgtt cattgcatct tgataaagag cttcttcacc aaatttttgg
    48361 tcgaagatag ggcgtggaag gtgaccttta cggaaacctg gaacattaag agatttcttc
    48421 actgacttga agacacggtc caattctggt ttgatttggt cttgagagat agtgaaagtc
    48481 aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc atttctcctt
    48541 aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta gactaatgca
    48601 gacaattata gacaacaagc ctttttccta actaaaacac tcataaagta tagacaattt
    48661 tagactactt tggatatctt ttggttagtc attttccaaa actaatttat ctaatttttc
    48721 agttatatag ta
//
LOCUS       DAVLTG010000010        45815 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLTG010000010 DAVLTG010000000
VERSION     DAVLTG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.010"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(34..231)
                     /locus_tag="VYN12_000605"
     CDS             complement(34..231)
                     /locus_tag="VYN12_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1415039.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSSLSDISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(306..1082)
                     /locus_tag="VYN12_000606"
     CDS             complement(306..1082)
                     /locus_tag="VYN12_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1415040.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            1204..1950
                     /locus_tag="VYN12_000607"
     CDS             1204..1950
                     /locus_tag="VYN12_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1415041.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNMATLENAGIMVKVVS"
     gene            1963..2943
                     /locus_tag="VYN12_000608"
     CDS             1963..2943
                     /locus_tag="VYN12_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1415042.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3138..3458
                     /locus_tag="VYN12_000609"
     CDS             3138..3458
                     /locus_tag="VYN12_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1415043.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3504..3812
                     /locus_tag="VYN12_000610"
     CDS             3504..3812
                     /locus_tag="VYN12_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1415044.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3829..5127
                     /locus_tag="VYN12_000611"
     CDS             3829..5127
                     /locus_tag="VYN12_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1415045.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPTIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            5278..7716
                     /locus_tag="VYN12_000612"
     CDS             5278..7716
                     /locus_tag="VYN12_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1415046.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7735..8403
                     /locus_tag="VYN12_000613"
     CDS             7735..8403
                     /locus_tag="VYN12_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1415047.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            8421..9509
                     /locus_tag="VYN12_000614"
     CDS             8421..9509
                     /locus_tag="VYN12_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1415048.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            9964..12465
                     /locus_tag="VYN12_000615"
     CDS             9964..12465
                     /locus_tag="VYN12_000615"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1415049.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLIRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            12659..13354
                     /locus_tag="VYN12_000616"
     CDS             12659..13354
                     /locus_tag="VYN12_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415050.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13366..13782
                     /locus_tag="VYN12_000617"
     CDS             13366..13782
                     /locus_tag="VYN12_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415051.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(14409..14501)
                     /locus_tag="VYN12_000618"
     CDS             complement(14409..14501)
                     /locus_tag="VYN12_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1415052.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            14662..15633
                     /gene="ruvB"
                     /locus_tag="VYN12_000619"
     CDS             14662..15633
                     /gene="ruvB"
                     /locus_tag="VYN12_000619"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1415053.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            15614..16186
                     /locus_tag="VYN12_000620"
     CDS             15614..16186
                     /locus_tag="VYN12_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1415054.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            16417..17175
                     /locus_tag="VYN12_000621"
     CDS             16417..17175
                     /locus_tag="VYN12_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1415055.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALIKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17184..17987
                     /locus_tag="VYN12_000622"
     CDS             17184..17987
                     /locus_tag="VYN12_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1415056.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLNKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18009..19268
                     /gene="rseP"
                     /locus_tag="VYN12_000623"
     CDS             18009..19268
                     /gene="rseP"
                     /locus_tag="VYN12_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1415057.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19281..21134
                     /locus_tag="VYN12_000624"
     CDS             19281..21134
                     /locus_tag="VYN12_000624"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1415058.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21234..22613
                     /gene="bglA"
                     /locus_tag="VYN12_000625"
     CDS             21234..22613
                     /gene="bglA"
                     /locus_tag="VYN12_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1415059.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            22805..24613
                     /gene="glmS"
                     /locus_tag="VYN12_000626"
     CDS             22805..24613
                     /gene="glmS"
                     /locus_tag="VYN12_000626"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1415060.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            24732..25781
                     /locus_tag="VYN12_000627"
     CDS             24732..25781
                     /locus_tag="VYN12_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1415061.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(25881..29678)
                     /gene="spuA"
                     /locus_tag="VYN12_000628"
     CDS             complement(25881..29678)
                     /gene="spuA"
                     /locus_tag="VYN12_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1415062.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            30095..30508
                     /gene="rpsL"
                     /locus_tag="VYN12_000629"
     CDS             30095..30508
                     /gene="rpsL"
                     /locus_tag="VYN12_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1415063.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            30528..30998
                     /gene="rpsG"
                     /locus_tag="VYN12_000630"
     CDS             30528..30998
                     /gene="rpsG"
                     /locus_tag="VYN12_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1415064.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            31423..33504
                     /gene="fusA"
                     /locus_tag="VYN12_000631"
     CDS             31423..33504
                     /gene="fusA"
                     /locus_tag="VYN12_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1415065.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            33608..37999
                     /locus_tag="VYN12_000632"
     CDS             33608..37999
                     /locus_tag="VYN12_000632"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1415066.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            38101..38364
                     /locus_tag="VYN12_000633"
     CDS             38101..38364
                     /locus_tag="VYN12_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1415067.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            38357..38635
                     /locus_tag="VYN12_000634"
     CDS             38357..38635
                     /locus_tag="VYN12_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1415068.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            38656..38808
                     /locus_tag="VYN12_000635"
     CDS             38656..38808
                     /locus_tag="VYN12_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415069.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            38830..40071
                     /locus_tag="VYN12_000636"
     CDS             38830..40071
                     /locus_tag="VYN12_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1415070.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            40081..40311
                     /locus_tag="VYN12_000637"
     CDS             40081..40311
                     /locus_tag="VYN12_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1415071.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            40624..41346
                     /locus_tag="VYN12_000638"
     CDS             40624..41346
                     /locus_tag="VYN12_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1415072.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            41563..42897
                     /gene="pepC"
                     /locus_tag="VYN12_000639"
     CDS             41563..42897
                     /gene="pepC"
                     /locus_tag="VYN12_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1415073.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(42953..43864)
                     /locus_tag="VYN12_000640"
     CDS             complement(42953..43864)
                     /locus_tag="VYN12_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1415074.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(43888..44691)
                     /locus_tag="VYN12_000641"
     CDS             complement(43888..44691)
                     /locus_tag="VYN12_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1415075.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(44719..45708)
                     /gene="manX"
                     /locus_tag="VYN12_000642"
     CDS             complement(44719..45708)
                     /gene="manX"
                     /locus_tag="VYN12_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1415076.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT        13558 a         8307 c        10379 g        13571 t
ORIGIN      
        1 tagagtaaaa ttctctacaa aaagaagaat agcctatttt actattcttc cgagtgattt
       61 caatttcttt ggggaaatat ggagatactt tttaaatact ttggcaaaat atttatagtc
      121 tgaaaatcca acttggtcag agatatcgct taaagaggag ttgggagatt cagccatctt
      181 atctatagct tgtttcaggc gatattgtaa gatatattca tttagagtca tggggaagtc
      241 ttctttgata accttatata gatgcttgtt atctgcaaat agctagagca tttcaaggaa
      301 ataaactaga aataacaatt aatatggtgg ttcagaaata ccttttgata atcaataaga
      361 tcttcaggat gaagtgcgtt gactccatcc atttcatatt tccgatttaa taaacgatat
      421 ttgttttcac caaattgatg aaaagggagt agttgaactt ggtcgatatt taatgagtta
      481 aatagagtag cgaatttttc tgcatcctct aaactattgt taaaattagg aataactggg
      541 attcttaaaa cgatagtttt attttgagaa aaagcataat gaatgttttt aataatcatt
      601 tgattaaaaa ccccagtcac ttttttatgt tttatagaat tataatgttt taggtctgtg
      661 tagataaaat ccacatattg aattaaatca ataaattttt catgatcaac aaaggcagta
      721 gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt ttaagatggc tttagcaaat
      781 tcaaactgag caaatatttc acctcctgat aaagttaaac ctccaccgga ttcttcgtaa
      841 aattctttgt cttttaatac ctctgtaata atttcttcta cagtcttttc ttcaccgact
      901 aaggtgaatt tctctcgttg agcatctttc attttttcag gtttcattct ttgagattca
      961 ggattagaac accatggaca gcgcagagga catcctttta aaaaaacagt tgtacgaata
     1021 cccggaccgt catgaattga aaagtgttga atattaaaaa taattccttt agatatttcc
     1081 ataagagttc ctcctcttca taagtctatc ctatcacaaa aacgaaagaa aaacaattac
     1141 gaacgaaagg ttaatttgtt gttttttgct ttttattttg gtagaataaa acggaggtgt
     1201 aaaatgaaaa gattggaaca aattattaaa ttagtatcag aatatgaaaa gatcgacgtt
     1261 aatacattat cggaaaaatt aaatgtatcg aaagtaacga ttagaaaaga tttagataaa
     1321 ttagagtcaa aaggtttatt acacagagag catggatatg ctgtattaaa tagtggagat
     1381 gacttaaatg tacgtttgtc aattaactat gaaattaaga gaaaaattgt tcaggaagca
     1441 gtaaaattgg tgtcagataa tgaaacaata atgatagaat ctggatcgac ctgtgcttta
     1501 cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga ttgtaacaaa ttcatttttt
     1561 atagcaaatt ttgtgagagc ttatgattca tgtcgtatta ttgttcttgg tggagagttt
     1621 cagaaggatt cacaggttac tgtgggacct ttattaaaag aaatgataca gacttttcat
     1681 gtgcgtcaag cttttgttgg gacagatggc tacgataaag agatgggctt tacaggaaaa
     1741 gatttaatgc gcagtgaggt agttcaatat atttcagcag cgtcggataa agtcattgtg
     1801 ctaactgact caagtaaatt tgataaaagg ggtacagtaa gaagatttgc tttaagtcaa
     1861 gtctatgaag taataacaga cgaaaaactt tctaaacaaa atatggctac attagaaaat
     1921 gctgggataa tggttaaggt agtttcgtaa gaggttaagt gtatgaatca agataggaat
     1981 aaactgctct ctaaaattgc ttatctgtat tatattgaaa acttaaatca gtcacaaata
     2041 gcagcaaaat taggaattta tagaacctct attagtagaa tgttaacaga agcaaggaat
     2101 gcaggaattg ttaaaattga aatagagaat tttgatacca atatgtttaa gttggaaaat
     2161 tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta ttccaaatga atttgatgat
     2221 aatccaacaa ttttatctga aagaatttct caagttgcag caggtgtcct taggaatcta
     2281 attgatgata atatgaaaat tggcttttct tgggggaaaa gtttaagtaa tttagtagat
     2341 ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc ctctagcagg tggtcctagt
     2401 cacatacacg ctaaatacca tgtgaataca ctgatttatg aaatgtctag aaaatttcat
     2461 ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa ataaattgtt agcagatggt
     2521 attttgcaat caagatattt tgaaaatttg aaaaatagtt ggaaagattt agatatagct
     2581 gtagtcggaa ttggtgattt tagcaataaa ggaaagcatc aatggttaga catgcttaca
     2641 gaggatgact ttaaagaatt gaccaaagtt aaaactgtag gagaaatttg ttgtcgattt
     2701 tttgattcaa aaggtaaaga agtctatgaa aacttacagg aaagaacgat agcaatctct
     2761 ttggaagatt taaaaaatat tcctcaaagt ttagctgttg cttacggtga tacgaaagta
     2821 tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc atttgattac agacaaaaat
     2881 acaattttaa aagttttgga agaagatggg gatttgactt ttagagagat tctaggtgag
     2941 tgaaaatgat agactgattc agtttatcgt ttttcttttt agttgattgc acatttgtgc
     3001 ttatataaac aaaaatagtt tatctgttgt ttttggattg acaactttat tatgtagttg
     3061 tattctatag ttacaaaaga aaattttaaa atttcaaatg aaaaaagctt tttacatagt
     3121 gaaatgagga ggaatttatg gaaattattg ttccagatca aattatcatg ggtttaattt
     3181 tatatgctgg cgatgcgaaa caacatattt ataaagcatt agattacata aagaacggta
     3241 catgtgaacg atgtgaagaa gaaatccagt tagctgatgc agccttatta gaagctcata
     3301 atctacaaac aaaattcttg gcacaggaag cgtctggtac aaagacagaa attacagctc
     3361 tctttgttca ttcacaagat catctcatga ctagtatgac ggagattaat ttaatcaaag
     3421 aaattattag tttgagaaaa gaacttcata aaaaataata ctagagtatt atcattgtta
     3481 ttaacataga ggaggaaaac ataatggtga agattggttt gttttgtgca gcaggttttt
     3541 ctactggtat gcttgtaaat aatatgaaaa ttgcagcgca atctagtgga gttgaggcag
     3601 aaatagaggc gttttctcag tctaaattag cggattatgc gccaaatata gatgttgcac
     3661 tattgggtcc acaagttgct tatacattag ataaatcaaa agaaatttgt gataagtgtg
     3721 atgttccgat agctgttatt ccgatgatgg actatggtat gttagatggg aaaaaagtat
     3781 tagatttggc cctatctttg attagtgggt aagaaaagga gatttattat gtcaaagatg
     3841 gatgttcaga aaatcattgc accgatgatg aagtttgtga atatgcgtgg cattatagct
     3901 ctaaaagatg ggatgttagc aattttacca ttgacagtag ttggtagttt gttcttgatt
     3961 atgggacaat tgccgttcga aggattaaat aagagcattg ctagtgtttt tggagctaat
     4021 tggacagagc cgtttatgca agtatattca ggaacttttg ctattatggg tctaatttct
     4081 tgtttttcaa ttgcctattc ttatgctaag aatagcggag tagaggcttt accagctgga
     4141 gttctatctg tatctgcatt ctttattttg ctaagatcgt cttatatccc taaacaaggt
     4201 gaggcgattg gggacgctat tagtaaagtt tggtttggag gccaaggaat tatcggtgct
     4261 atcattatag gtttggtagt aggaagtatt tataccttct ttataaagag aaaaattgtt
     4321 attaagatgc cagaacaagt tccacaagct attgccaaac agtttgaagc aatgattcca
     4381 gcatttgtaa ttttcttatc ttctatgatt gtatatattt tagcgaagtc attgactaat
     4441 ggcggaacat tcatagaaat gatttattct gctattcaag ttccgttgca aggtttaact
     4501 ggatctttgt atggtgctat tggaattgca ttctttatat catttttgtg gtggtttggt
     4561 gttcatgggc aatcggtagt aaatggagta gtgacagctc tgcttttatc taatcttgat
     4621 gctaataaag ctatgttagc ctctggtaat ctatcattag aaaatggtgc acatattgtt
     4681 actcaacaat ttttagattc atttttaatt ctatcaggtt cagggattac gtttggtctt
     4741 gtagttgcca tgctttttgc agcaaaatca aaacaatacc aagccttagg aaaagttgca
     4801 gcttttccaa caatatttaa cgtaaatgag ccagttgtat ttggatttcc gattgtcatg
     4861 aatccagtta tgtttgtacc tttcattctt gttcctgtac ttgcagctgt gatagtatat
     4921 ggagctattg caacaggttt catgcaacca ttctcagggg taacattgcc ttggagtaca
     4981 ccagctattc tatcaggatt tttggtgggt ggatggcaag gtgttgtgac tcagttatta
     5041 gtattggtga tatctacagt ggtttacttt ccattcttta agatacaaga tcgtttagct
     5101 taccaaaatg aaatcaaaca atcttagagg tatttgtgtg ttactgttaa actcacacat
     5161 ttgtgctaaa aattagagag ttaaaatttt tctagttaaa agcttgaaaa tttctataaa
     5221 aatcggtatt atattttcga aagaaataaa aatattttcg aaagaaaggt gcttacgatg
     5281 gtaaatacag aagtagcaag aacaacaatc aagacagaat attttggcag ccttactgaa
     5341 aggatgaaca aatatcgaga agatgtttta aataaaaaac cttatattga tgctgagaga
     5401 gcagttctag caacacgcgc ctatgaacga tacaaggaac aacctaatgt cctaaaacgt
     5461 gcatatatgc tgaaagaaat tttggaaaat atgtctatct atattgaaga agaatctatg
     5521 attgcgggaa atcaagcttc ttccaataaa gatgctccta tttttccgga atatacgcta
     5581 gaatttgttc tcaatgagtt ggatcttttt gaaaagcgtg atggagatgt tttctatatt
     5641 acagaagaaa caaaagaaca acttagaagt attgctccgt tttgggaaaa taataattta
     5701 cgtgctagag ctggtgcctt attacctgaa gaagtgtctg tttatatgga aacaggattc
     5761 ttcggtatgg aaggtaagat gaattctgga gatgctcact tagcagttaa ctatcagaaa
     5821 cttttgcaat ttggtttaag aggttttgaa gagcgggctc gtaaagcgaa ggtagctcta
     5881 gatttaacag atccagcaag tattgataaa tatcattttt acgactctat atttatcgta
     5941 atcgatgcta ttaaagtata tgcaaagcgc tttgttgctc ttgctaaaag tttagccgaa
     6001 aatgcaaatc ctaaacgtaa gaaagaatta cttgagattg cagatatttg ctctagagtc
     6061 ccatatgaac cggcaactac ttttgcagaa gctattcaat cagtttggtt tattcaatgt
     6121 attttacaaa ttgaatctaa tggccactct ctttcatatg gccgttttga tcaatatatg
     6181 tatccatata tgaaggctga tttagaaagt ggtaaagaaa cagaagatag cattgttgaa
     6241 cgtctgacaa atctttggat taagacaatt acaattaata aggttcgcag tcaatcacat
     6301 acattttctt cagcaggaag tcctttatat caaaatgtta caattggtgg acagactcga
     6361 gataagaagg atgctgttaa cccattatct tatttggtat taaaatcagt tgcacaaacc
     6421 catctaccgc aacctaatct aactgtacgt taccatgcag gtttagatgc tcgtttcatg
     6481 aatgagtgta ttgaagtgat gaaacttggt tttggtatgc ctgcatttaa taatgatgag
     6541 attattattc cttcttttat tgcaaaagga gtattggaag atgatgctta tgattacagt
     6601 gccattggat gtgttgaaac ggcagttcca gggaaatggg gctatcgttg cacaggtatg
     6661 agttatatga acttccctaa ggttctactt atcacgatga atgatggaat tgatccggct
     6721 tcgggtaaac ggtttgcacc aagctttggt cattttaagg atatgaagaa cttttctgaa
     6781 ttagaaaatg cttgggataa aacactaaga tatttgacac gaatgagtgt tattgttgaa
     6841 aattctattg atttatcatt ggaacgagaa gttcctgata ttctatgttc agcattgact
     6901 gatgattgta ttggtcgtgg aaaacacctt aaagaaggtg gagcagtata tgattatata
     6961 tcaggattgc aagttggaat tgcaaatttg tcggattcat tagctgcaat taaaaaattg
     7021 gtgtttgagg aagaacgtat aagcccaagt cagctttggc atgcactgga aacagattat
     7081 gccggagaag aaggtaaggt cattcaagaa atgttgattc atgatgcacc taagtatggt
     7141 aatgatgatg attatgctga caaattggtt actgctgctt atgacattta tgttgatgaa
     7201 attgctaaat atcctaatac acgttatgga agagggccta ttggaggaat tcgttattca
     7261 ggaacatctt ctatatcagc caacgtaggg cagggacgtg gaacattagc aactccagat
     7321 ggacgcaacg cgggtacacc gttagcagag ggttgttcac catcacataa tatggatcaa
     7381 cacggcccta catctgtttt aaaatctgtt tcaaaattac caacagatga aatcgtaggt
     7441 ggggttctct taaatcagaa agtaaatcct caaacgttag ccaaagaaga agataaatta
     7501 aaactaattg ctttgttacg aacattcttt aatcgtttac atgggtacca tattcaatac
     7561 aatgttgttt ccagagagac gttgattgac gctcagaaac atcctgaaaa acacagagac
     7621 ttaattgttc gtgttgcagg atactctgca ttcttcaatg ttctttctaa ggcaacccaa
     7681 gatgacatta taggacgtac tgagcatact ttgtaaaata aagaggttct ttttatggaa
     7741 tttatgcttg acacattaaa tttagatgag attaaaaagt ggtctgaaat tttgccgcta
     7801 gctggggtaa cttcaaatcc cactattgca aaaagagagg gttctattaa tttttttgaa
     7861 cgaatcaaag atgtaagaga attgattggc tctacaccct ctattcatgt tcaggtgatt
     7921 tctcaagatt ttgaaggcat cttaaaggat gctcatgaaa ttcgaagaca agcaggagat
     7981 gatatattta tcaaagtacc tgttactcca gctggattac gtgcaataaa ggtgctaaaa
     8041 aaagagggct accatatcac tgcaacagct atttatacag ttattcaggg attattagct
     8101 atcgaagcag gagcggatta cctagctcca tattataata gaatggaaaa tctgaacatt
     8161 gattcaaatt ctgtcattcg tcaattagct cttgctattg atagacagaa ctctcctagt
     8221 aagattttag ctgcatcctt taaaaatgta gcacaagtaa ataatgcttt agctgcaggt
     8281 gcgcatgctg ttacagcagg agcagatgtt tttgaatcag ctttcgccat gccatctatc
     8341 caaaaggcgg ttgatgactt ttctgacgac tggtttgtta ttcaaaatag tcgttccatt
     8401 tagatagaga ggaaatacat atgagaattt ttgctagtcc ttctagatat attcaggggg
     8461 aaaatgcctt gtttgaaaat gccaaatcaa ttttggattt gggaaattgc cctattctat
     8521 tatgcgatca gttggtttat gatattgttg gaaaacgatt tgaagattat ctacataggt
     8581 atggtttcca tattgttctg gcgctattta atggtgaagc ttctgacaat gaaatcaatc
     8641 gagttgttgc cttggctgag aaagaaaatt gtgatagtat tatcggtctt ggtgggggaa
     8701 agacgattga tagcgcaaaa gctattgcag atttgattga aaagcctgtt attattgctc
     8761 caacaattgc atcgaccgac gcacctgtat ctgctttatc tgttatttat acagatgaag
     8821 gtgcatttga tcattatcta ttttattcta aaaatccaga tttagttttg gttgatacaa
     8881 aagttatttc acaagcccct aagcgtttat tagcgtctgg tattgcagat ggtttagcaa
     8941 cttgggttga ggcgcgtgcg gttatgcagg caaatggaaa aactatgttg ggacaacagc
     9001 aaacattggc tggagttgca attgcgaaga aatgtgaaga aacgctgttt gcagatggtt
     9061 tacaggctat ggcagcttgt gaagctaaag tggtgacacc agcattagaa aatattgttg
     9121 aagctaatac tttattgagt ggtctaggtt ttgaaagtgg aggattagct gcggcgcatg
     9181 caattcataa tggttttact gcattgacag gtgacattca tcatttaaca catggtgaaa
     9241 aagtagctta tggaacttta gtacaactat tattggaaaa tagacctaaa gaagaacttg
     9301 ataagtatat tgagttttac aaaaaaattg gtatgccaac aactctaaaa gaaatgcatt
     9361 tggatcaagt tggatatgat gatttaataa aagttggtaa acaagcaact atggagggtg
     9421 agacaattca tcagatgccg tttaagattt cgccttcaga tgttgctcaa gctattatcg
     9481 ctgtagatgc ctatgtaaat tcaaaataaa caataaggac tactgttttc caaatggtag
     9541 tcttttattg atcctcgtat tgaattctat agcagattga aataagatga gaacaaatcg
     9601 attgggaaag taaaattaat ttctaacaat gttttagcaa ttgtttcgta ctatttcaga
     9661 ttcagtgcac tatacgttct tcataaatca aaaagcgaca taggttgtcg gctatttatt
     9721 gtgaatacat taattagcat tccagtttta tcttcggtct aaaataagta ttttgtgcta
     9781 tacgagataa gcttcttgac ttactccttg atttactgca taacaatggg ataaaaagtg
     9841 ggagatagag caattcatag tcatcaaaat taatgagata cagtatacag tttttccttt
     9901 aaacacattt caaattccct caaaaatggt ataatagtaa catcacaaaa ttggagagag
     9961 accatgagtt tttataatca taaagaaatt gagcctaagt ggcagggcta ctgggcagaa
    10021 catcatacat ttaagacagg aacagatgca tcaaaaccta agttttatgc gcttgatatg
    10081 ttcccttatc cgtctggagc tggtctgcac gtaggacacc cagaaggtta tactgcaacc
    10141 gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg ttcttcaccc aatgggttgg
    10201 gatgcttttg gtttgcctgc agagcaatac gctatggata ctggtaatga cccagcagaa
    10261 tttacagcgg aaaacattgc caacttcaaa cgtcaaatca atgcgcttgg attttcttat
    10321 gactgggatc gtgaagtcaa cacaacagat ccaaactact acaagtggac tcaatggatt
    10381 ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg aagtgccagt aaactgggtt
    10441 gaggaattgg gaactgccat tgccaatgaa gaagtgcttc ctgacggaac ttctgagcgt
    10501 ggaggctatc cagttgtccg caaaccaatg cgccaatgga tgctcaaaat cacggcttac
    10561 gcagagcgct tgctcaatga cttagatgaa ctagattggt cagagtctat caaggatatg
    10621 caacgcaact ggattggtaa atcaactggt gccaatgtaa ctttcaaagt aaaaggaaca
    10681 gacaaggaat ttacagtctt tactactcgt ccggacacac ttttcggtgc gactttcact
    10741 gtcttggctc ctgaacatga attagtagac gctatcacaa gttcagagca agcagaagct
    10801 gtagcagact ataaacacca agccagcctt aagtctgact tgattcgtac agaccttgct
    10861 aaggaaaaaa ctggtgtttg gacaggtgcc tatgccatca accctgtcaa tggtaaggaa
    10921 atgccaatct ggattgcgga ctatgttctt gctagttatg gaacaggtgc ggttatggct
    10981 gtgcctgccc acgaccaacg tgactgggaa tttgccaaac aatttgacct tccaatcgtc
    11041 gaagtacttg aaggtggaaa tgtcgaagaa gctgcctaca cagaggatgg cctgcatgtc
    11101 aattcagact tcctagatgg attgaacaaa gaagacgcta ttgccaagat tgtggcttgc
    11161 ttggaagaaa aaggctgtgg tcaggagaag gttacctacc gcctccgcga ctggctcttt
    11221 agccgtcaac gttactgggg tgagccaatt ccaatcattc attgggaaga tggaacttca
    11281 acagctgttc ctgaaactga attgccgctt gtcttgcctg taaccaagga tatccgtcct
    11341 tcaggtactg gtgaaagtcc actagctaac ttgacagatt ggcttgaagt gactcgtgaa
    11401 gatggtgtca aaggtcgtcg tgaaactaac accatgccac aatgggctgg ttcaagctgg
    11461 tactacctcc gctatattga cccgcacaat actgagaaat tggctgatga ggacctcctc
    11521 aaacaatggt tgccagtaga tatctacgtg ggtggtgcgg aacatgctgt acttcacttg
    11581 ctttatgctc gtttctggca taaattcctc tatgacctcg gtgttgttcc gactaaggaa
    11641 ccattccaaa aactctttaa ccaagggatg attttgggaa caagctaccg tgaccaccgt
    11701 ggtgctcttg tggcaaccga caaggttgaa aaacgtgatg gttccttctt tcatatagaa
    11761 acaggggaag agttggagca agcgccagcc aagatgtcta aatcgctcaa gaacgttgtt
    11821 aacccagatg atgtggtgga acaatacggt gccgataccc ttcgtgttta tgaaatgttt
    11881 atgggaccac tcgatgcttc gattgcttgg tcagaagaag gtttggaagg aagccgtaag
    11941 ttccttgacc gagtttaccg tttgattaca agtaaagaaa tccttgcgga aaacaatggt
    12001 gctcttgaca aggcttacaa cgaaacagtc aaagctgtta ctgagcaaat tgagtctctc
    12061 aaattcaaca cagctattgc ccaacttatg gtctttgtca atgctgctaa caaggaagat
    12121 aagctttatg ttgactatgc caaaggcttt attcaattga ttgcaccatt tgcacctcac
    12181 ttggcagaag aactctggca aacagtcgca gaaacaggtg agtcaatctc ttatgtagct
    12241 tggccaactt gggacgaaag taaactggtt gaagacgaaa tcgaaatcgt tgtccaaatc
    12301 aaaggtaaag tccgtgccaa actcatggtc gctaaagacc tatcacgtga agaattgcaa
    12361 gaaattgctc tagcggatga aaaagtcaaa gcagaaattg acggtaagga aatcgtgaaa
    12421 gtgattagtg taccaaataa attggttaat attgttgtaa aataaccaat ttatttgctg
    12481 atttccaacc tcaaacagtt tcccaaactg tttgagccaa ctaaactcgt taatatcgtt
    12541 gtgaaataag gtaggaatcc ttcagagtag aatctggagg attttttgaa tcttcttatg
    12601 aaagtatggt atactatggg caactataaa gtttgaaaag tgaaaaaagg agaaagctat
    12661 gccagtaaat gaatatggtc aaatgattgg ggagtcaatg gaaggttata caccaggtga
    12721 actgccttct attgatttct tagaagggcg ttatgctagg atagaggctc tttcagtgga
    12781 aaagcatgcg gaggatttgc tagctgttta tggcccggat actcctcggg agatgtggac
    12841 ctaccttttt caggagccag tagcagatat gggggagctg gttagccttt tacatcagat
    12901 gttggctcgt aaggaccgtt tttactatgc aatcatagac aaggcgactg gtaaggcttt
    12961 gggatctttt tctctcatgc gcattgacca gaataaccga gtaatagaag tcggagcagt
    13021 cactttttct ccagagctaa ggggtacacg gataggaact gaagctcagt atctcctagc
    13081 tcgctatgtt tttgaggagc taaactatcg tcgctacgag tggaaatgcg atgccttaaa
    13141 tctgccatca agacgagctg cggagcgttt gagctttatt tatgaaggaa ccttccgtca
    13201 ggcagtggtt tataagggac gtacgagaga tacggattgg ttgtctatga ttgataagga
    13261 ctggcctcaa gtcaaagatc gtttggaaac atggttgcgt cctgaaaatt ttgataaaaa
    13321 tggacagcag tacaagagct tgagagaact ttaagaggtg ttgagatgat tactattaaa
    13381 aagcaagaaa ttgtcaagct agaggatgtt ttacatctct atcaggctgt cggttggaca
    13441 aattataccc atcaaccaga gatgctggag caggccttat ctcattcatt agtaatttat
    13501 ctggcacttg atggtgatgc tgtggtgggc ttgattcgtt tggttggaga tggattctca
    13561 tcagtattgg ttcaggattt aatcgtttta ccaatctatc agcgtcaagg aattggtagt
    13621 gccttgatga aagaggcttt agaggattac aaagatgcct atcaagtcca gctggtgaca
    13681 gaagagacag aaagaacctt gggcttctat cgttctatgg gctttgaaat cttatccacc
    13741 tataattgta tagggatgac ttggatgaat cgtaaaaaat aacaaaactt gttttttctt
    13801 aagcaaaatt taaggatggt ctagtattat atagtcatta aataaagacc tcctaacttt
    13861 atttaataaa atcctaaact tttctttttc ataataatct cccttaactt cacccaatca
    13921 ggtggagttt tttagctcta tttcaggctt ttggggacta ttctaaaaat aatttttcga
    13981 tatttttcgg tatttttcgg attttggtcg gggaattggc ggggactttt ttagcgaata
    14041 taactaagaa ataggtctgt ggtcgcttca gctagttcaa actcaatttg attgtaagtg
    14101 actgttaatt gaagaactgg aactactgta ataatgattt tgcttgtcta gtagtggcgt
    14161 attaaatgag aagtaacatg taagattgtc tcttcgttta cgaaatcaaa atttctatga
    14221 aattgataga atccttaacg ttctcttaat cttaaccgtc ttgtcgtaca gcggttgaag
    14281 aaaatgtaaa cctttgacaa aattcgtgaa ctatgggata ataaaaagga attgagtact
    14341 agttctatat cataggctag aaaagacccc aagctcacga ccaaataagc ttgaggtctt
    14401 ttttgacact atttgtcctt gtttagccat ttatcgacta tacgaagaac gacaccgacc
    14461 acaattggtc cgatgatagt tttgagtact aattccatca tgggctatct cacctccttt
    14521 cgtaggcggt gtagcagtgt cgtagaatat tataccacat aagtgctaaa cttaggagtc
    14581 acccaatcag gtggcttttt tgtttgtggc ttggtttttt gatataatag agccatgagt
    14641 agaattttag ataatgagat aatgggggat gaggagttag tagaacgcac gctccgtcct
    14701 cagtatttac gtgaatatat cggacaggat aaggtcaagg accagctaca aatctttatt
    14761 gaagctgcca aaatgcggga tgaagcgctg gatcatgtgc tcttatttgg gcctccaggt
    14821 ctcgggaaaa cgaccatggc ctttgttatt gccaacgaac tgggagtcaa tcttaagcag
    14881 acgtcgggtc cagtcattga aaaagccgga gatctggtag ctattttgaa tgagttagag
    14941 cctggggatg tactttttat tgatgagatc catcgtttgc caatgtcagt ggaagaggtg
    15001 ctttatagtg ctatggagga cttctacatc gatattatga ttggggctgg tgagggtagt
    15061 cgtagtgttc atttggagtt accacctttt accttgattg gtgcgacgac tcgggctggt
    15121 atgctctcca atccgctacg ggcacgtttt gggattacag gccatatgga gtattatgcc
    15181 catgctggct tgacagaaat tgtcgagcgg acggcagata tttttgagat ggaaatcact
    15241 catgaggcag catctgagtt ggccctacgt agtcgtggga cccctcgtat tgccaatcgt
    15301 ctcctcaagc gcgtgcgcga ttttgcccag ataatgggga atggggtaat tgatgatatt
    15361 attaccgata aggctttgac tatgctggat gttgaccatg aaggtttgga ctatgtggat
    15421 caaaaaatcc ttcgtaccat gattgagatg tacagtggag gacctgttgg tctaggaact
    15481 ctttctgtga atatcgccga agagcgtgag acagttgaag atatgtatga gccttacttg
    15541 attcaaaaag gttttatcat gcggacacgg tctggacggg tggcgactgc taaggcatat
    15601 gagcacttag gttatgaata cagtgaaaaa taagcaagaa atcttagagg cttttagaga
    15661 aaatccagat atgatggcca ttctgacgat catccgagac cttggtctga aagactcgtg
    15721 gttggcagca ggttctgtca gaaatttcat ttggaatctt ttgtcagaca aatccccttt
    15781 tgatcatgaa acagatatag atgtgatttt ctttgatcca gatttttctt atgaggaaac
    15841 cttattactg gagaaaaagc tgcgagagga ttttcctcag taccagtggg aattgaaaaa
    15901 tcaggtctat atgcatcagc acagtcctca cactgcttcc tataccagtt ctcgtgatgc
    15961 tatgagtaag tatccagaac ggtgtacgac agttggactg cgcttgaatg aagaatcaga
    16021 ttttgaactc tatgcacctt atggtttgga ggatattttg aattttcaag ttcgtccaac
    16081 tcctcatttc ttagaaaatg aagaccgaat ggaactctat caaacacgtt tatccaagaa
    16141 aaattggcag gagaaatgga aaaatttgat ttttaaaaat acttaaggaa actttaagct
    16201 agggagtgta cactaagttc ataagttaag aagaccttaa cttaaactcc taaaactttt
    16261 tcataataat ctccctataa aaataaagtc gcccaatcag gcggcttatt tttttgaaaa
    16321 atgggcttgg tgcctgagaa taaatagctt agtgatagaa gaaaatgggg aaatatggta
    16381 taatgaaacg atagattttt gaataggaat aagatcatgt ttggattttt taagaaagat
    16441 aaggctgtgg aagtagaggt tccgacacag gttcctgctc atatcggcat catcatggat
    16501 ggcaatggcc gttgggctaa aaaacgtatg caaccgcgag tttttggaca taaggcgggc
    16561 atggaagcat tgcaaaccgt gaccaaggca gccaacaaac tgggcgtcaa ggttattacg
    16621 gtctatgctt tttctacgga aaactggacc cgtccagatc aggaagtcaa gtttatcatg
    16681 aacttgccag tagagtttta tgataattat gtcccggaac tacatgcgaa taatgttaag
    16741 attcaaatga ttggggagac agaccgcctg cctaagcaaa cctttgaagc tttaatcaag
    16801 gctgaggaat tgactaagaa caacacagga ttgattctta attttgctct taactatggt
    16861 ggacgtgctg agattacaca ggcgcttaag ttgatttccc aggatgtttt agatgccaaa
    16921 atcaacccag gtgacatcac agaggaattg attggcaact atctctttac ccagcatttg
    16981 cctaaggact tacgagaccc agacttgatt atccgtacta gtggagaatt gcgtttgagc
    17041 aatttccttc catggcaggg agcctatagt gagctttatt ttacggacac cttatggcct
    17101 gattttgacg aagcagcctt gcaggaagct attcttgcct ataatcgtcg ccatcgccga
    17161 tttggaggag tttaggagga aatatgaccc aggatttaca gaaaagaacc ttgtttgcag
    17221 ggattgccct ggctattttc ctaccaattt taatgattgg gggcctcttg cttcagatag
    17281 caatcggaat catagccatg ctagccatgc atgaactttt gaagataaga ggtctagcga
    17341 ccatgacgat ggagggcctc ttgactctct ttgcaacctt tgcattaacc attcccttgg
    17401 agaattacct gacttttttg ccagttgatg ggaatgtggt tgcctatagt gttttgattt
    17461 caatcatgtt aggaacgacc gtttttagca agtcttatac gattgaggat gcggttttcc
    17521 ctcttgctat gagcttctac gtgggctttg gatttaatgc tttactagat gctcgtgttg
    17581 caggtttgaa caaggctctc ttagccttgt gtatcgtctg ggcgacagac agtggtgcct
    17641 atcttgttgg gatgaactat gggaaacgaa agttagcacc aagggtatcg cctaataaaa
    17701 cccttgaggg tgccttgggt ggtattttag gagcaatttt agtaaccatt atctttatga
    17761 tagttgacag tacagttgct cttccatatg gaatttacaa gatgtcagtc tttgctattt
    17821 tctttagcat tgctggacaa tttggtgatt tactagaaag ttcgatcaaa cgtcattttg
    17881 gtgttaagga ttctgggaaa tttatccctg gacatggtgg tgttttggat cgtttcgata
    17941 gtatgttgct tgtatttcca atcatgcact tatttggact cttttaatca aaagacggag
    18001 gaaacgctat gctcggaatt ttaaccttta ttctggtttt cgggattatt gtagtggtgc
    18061 acgagttcgg gcacttctac tttgccaaga aatcagggat tttagtacgt gaatttgcca
    18121 tcggtatggg acctaaaatt tttgctcaca ttggcaagga tggaacggcc tataccattc
    18181 gaatcttgcc tctgggtggc tatgtccgca tggccggttg gggtgatgat acaactgaaa
    18241 tcaagacagg aacgcctgtt agtttgacac ttgctgatga tggtaaggtt aaacgcatca
    18301 atctctcagg taaaaaattg gatcaaacag ccctccctat gcaggtgacc cagtttgatt
    18361 ttgaagacaa gctctttatc aaaggattgg ttctggaaga agaaaaaaca tttgcagtgg
    18421 atcacgatgc aacggttgtg gaagcagatg gtactgaggt tcggattgca cctttagatg
    18481 ttcaatatca aaatgcgact atctggggca aactgattac caattttgca ggtcctatga
    18541 acaattttat cttaggtgtc gttgtttttt gggttttaat ctttatgcag ggtggtgtca
    18601 gagatgttga taccaatcag ttccatatca tgccccaagg tgccttggcc aaggtaggag
    18661 taccagaaac ggcacaaatt accaagattg gctcacatga ggttagcaac tgggaaagct
    18721 tgatccaagc tgtggaaaca gaaaccaaag ataagacggc accgactttg gatgtgacta
    18781 tttctgaaaa ggggagtgac aaacaagtca ctgttacacc cgaagatagt caaggtcgtt
    18841 accttctagg tgttcaaccg ggggttaagt cagattttct atccatgttt gtaggtggtt
    18901 ttacaactgc tgctgactca gctctccgaa ttctctcagc tctgaaaaat ctgattttcc
    18961 aaccggattt gaacaagttg ggtggacctg ttgctatctt taaggcaagt agtgatgctg
    19021 ctaaaaatgg aattgagaat atcttgtact tcttggcaat gatttccatc aatattggga
    19081 tttttaatct tattccgatt ccagccttgg atggtggtaa gattgtgctc aatatcctag
    19141 aagccatccg ccacaaacca ttgaaacaag aaattgaaac ctatgtcacc ttggccggag
    19201 tggtcatcat ggttgtcttg atgattgctg tgacttggaa tgacattatg cgactctttt
    19261 ttagataatc gaggaatatt atgaaacaaa gtaaaatgcc tatcccaacg cttcgcgaaa
    19321 tgccaagcga tgctcaagtt atcagccatg ctcttatgtt gcgtgctggt tatgttcgcc
    19381 aagtttcagc aggtgtttat tcttatctac cacttgccaa ccgtgtgatt gaaaaagcta
    19441 aaaacatcat gcgccaagaa ttcgaaaaga ttggtgctgt tgagatgttg gctccaaccc
    19501 ttcttagtgc agaattgtgg cgtgaatcag gtcgttacga aacctatggt gaagaccttt
    19561 acaaactaaa aaaccgtgaa aaatcagact ttatcttagg tccaactcac gaagaaacct
    19621 ttacagctat tgtccgtgat tctgttaaat cttacaagca attgccactc aacctttatc
    19681 aaattcagcc caagtatcgt gatgaaaaac gcccacgtaa tggacttctt cgtacacgtg
    19741 agtttatcat gaaggatgct tatagtttcc acgctaacta tgatagtttg gatagtgttt
    19801 atgatgagta caaagcagcc tatgagcgta ttttcactcg tagtggttta gacttcaagg
    19861 ctattattgg tgacggtgga gccatgggtg gtaaggatag ccaagaattt atggccatta
    19921 catctgctcg tacagacctt gaccgctggg ttgtcttgga caagtcagtt gcctcatttg
    19981 acgaaattcc tgcagaagtg caagaagaaa tcaaggcaga attgctcaaa tggatagtct
    20041 ctggtgaaga taccattgct tactcaagtg agtctagcta tgcagctaac ttagaaatgg
    20101 caacaaacga gtacaaacca agcaaccgtg ttgtcgctga agaagaagtt actcgtgttg
    20161 caacgccaga tgttaaatca attgatgaag ttgcagcctt cctcaatgtt ccagaagaac
    20221 aaacgattaa aaccctcttc tacattgcag atggtgagct tgttgcagcc cttctagttg
    20281 gaaatgacca actcaacgaa gtcaagttga aaaatcactt gggagcagat ttctttgacg
    20341 ttgctagcga agaagaagtg gcgaatgttg ttcaagcagg atttggttca cttggaccag
    20401 ttggtttgcc agagaatatt aaaattattg cagatcgtaa ggtgcaagat gttcgcaatg
    20461 cagttgtcgg tgctaacgaa gatggctacc acttgactgg tgtgaaccca ggccgtgatt
    20521 ttactgcaga atatgtggat atccgtgaag ttcgtgaggg tgaaatttcc ccagatggac
    20581 aaggtgtcct taactttgcg cgtggtattg agatcggtca tattttcaaa ctcggaactc
    20641 gctactcagc aagcatggga gcagatgtct tggatgaaaa tggtcgtgct gtgccaatca
    20701 tcatgggatg ttacggtatc ggtgtcagcc gtcttctttc agcagtgatg gagcaacacg
    20761 ctcgcctctt tgttaacaaa acgccaaaag gtgaataccg ttacgcttgg ggaatcaatt
    20821 tccctaaaga attggcacca tttgatgtgc atttgattac tgtcaatgtc aaggatgaag
    20881 aagcgcaagc cttgacagaa aaacttgaag caagcttgat gggagctggt tatgaagtct
    20941 tgacagatga ccgtaacgaa cgtgtcggtg ttaaatttag cgatagtgac ttgattggtc
    21001 ttccaatccg tatcactgtt ggtaaaaaag cggccgatgg cattgtagaa gttaagatca
    21061 aggcaactgg tgacaccatt gaggttcatg cagataacgt gcttgaaacg cttgaaatcc
    21121 taagcaagaa ataaaaacta taatcagaag aaaaacaagg aaaaaatgta actagttttt
    21181 accttgtttt ttctgtataa tgggagaaat gagtagataa agaggtaaat gttatgctaa
    21241 gatttccaaa ggattttgtc tggggatcct ctacttctgg accgcagaca gaaggacgtg
    21301 tagctggtga cggtaaggga gacaatctct gggattactg gttccaagtg gagccaaatc
    21361 gttactataa tgggattggt tcagataaga catcgacttt ttatgaaaat tgggagcggg
    21421 atattgagct tttgttagag actggtcaca cagtctttcg gacttctatt cagtggtcac
    21481 ggatttttcc acaaggctgt ggaaaagtca accctcaagg tgtggatttt tatcgtaagg
    21541 tctttgaggc tattaaggct aaaggaattc gtctgttagt caatctctat cattttgatt
    21601 taccttttgc ccttcaagag gatggtgatg gttgggaaaa taaggcgaca gtctcagcct
    21661 atgaagacta tgctcgtttt tgttttgaga cttatggaga tttagtggat caatggatta
    21721 cctttaacga gcccatcgtt cctgtagaat ttggttattt ttatgatgcc cattatccac
    21781 ataaggtgga tgcagaggca gctgttaagg tagcctatca tacacaattg gccagcagcc
    21841 gggctgttaa ggcttgccat gaacttttgc ctgattccaa gattgggatt gtcctcaact
    21901 tgacaccggc ttatccacgt agccagcatc ctgctgatgt caaggcagct cgtattgcgg
    21961 ccctttttca ggcccaatct ttcttagatc catctgtctt ggggacttat ccacaggagt
    22021 tggtagaaat cttgcatgaa cacggtcttt tacctgatgc tacagaggaa gagttggaac
    22081 tcattcgtga taatacggtg gacttccttg gtgtgaacta ctatcaacct ttgcgtgtta
    22141 tggctcctcg atttgctaag catccagata gtccactctt accagaacat ttttacgagc
    22201 cttatgtgat gcctggacgt aaaatcaatt ctcaccgtgg ttgggagatt tatgagcaag
    22261 ggatttatga catcgcccaa aatatcaagg aaaattatgg caatattgag tggatgttga
    22321 ctgagaatgg tatgggtgtt gaaggggaag aaaaattccg tcaagatgga atgattcaag
    22381 atgattaccg tattgacttt gtaaaaggtc atcttcgtga acttcaccgt gccattgaag
    22441 atggtgccaa ctgtaagggc tacttgattt ggacctttat tgactgctgg tcatggctca
    22501 acagctataa aaatcgctat ggtttggtcg aattagactt ggaaacgcaa gaacgtcgtc
    22561 tgaagaaatc aggccactgg ttcaaagaat taagcgataa taatggattt taaaaaggac
    22621 tctgactgat tatcccaatc ggtcagagtt ttttgcttac aggagcttaa tttgaactat
    22681 accaattttt actcttgaca agtgaaagaa acaagtatat actgtttttg ctgattctat
    22741 aaaagatgaa ttagactata ccaattttaa ggagaaagca cagcttgcct gtgtcgtata
    22801 tactatgtgt ggaattgttg gtgttgttgg aaacacaaat gcaactgata ttttgattca
    22861 agggcttgaa aagcttgaat accgtggcta tgattctgcg ggaatttttg tcctagatgg
    22921 tgctgataac catttggtga aggctgttgg tcgtatcgca gaattgtctg ccaagacagc
    22981 tggtgttgag ggaacaactg gtatcggaca tactcgttgg gcaactcatg ggaaaccaac
    23041 ggaagacaat gctcacccac accgctctga gacagaacgt tttgtcttgg ttcacaatgg
    23101 ggtgattgaa aactaccttg aaattaaaga agaatacctt gctgggcacc acttcaaagg
    23161 gcaaacagat acggaaatcg ccgtacattt gattggaaaa tttgcggaag aagacggtct
    23221 ctcagttctt gaagccttta aaaaagctct tcatattatc cgtggttcat atgcctttgc
    23281 cttgattgac tctgaaaatc cagatgtcat ctatgtagcg aaaaacaaat ctccactttt
    23341 gattggtctt ggggaaggct acaatatggt ctgctcagat gctatggcta tgattcgtga
    23401 aaccaaccaa tacatggaaa ttcatgacca agagttggta atcgtcaagg ctgatagcgt
    23461 ggaagttcaa gactatgatg gtaacagtcg tgaacgtgct agctatactg cggaacttga
    23521 cttgtcagat atcggtaagg gaacttatcc ttactacatg cttaaggaaa ttgatgagca
    23581 accaactgtt atgcgtaaac tcattcaagc ctacacggat gatgctggtc aagtagtgat
    23641 tgatcctgct atcattaagg ctgttcaaga cgcagaccgc atctacatcc ttgcagctgg
    23701 aacatcttac catgcaggat ttgcttctaa gaaaatgttg gaagaattga cagatacacc
    23761 agttgaactt ggcatctcat ctgagtgggg ctacggtatg ccacttctca gcaagaaacc
    23821 actcttcatc tttatcagcc aatctggtga aacagcggat agtcgtcaag ttttggtcaa
    23881 ggctaatgaa atgggaattc caagcttaac agtgacaaac gttccaggtt caaccctctc
    23941 acgtgaagcc aactatacca tgctccttca cgcaggtcct gaaattgccg tggcatcaac
    24001 taaagcctat acagcgcaaa tcgcagccct tgccttcctt gcaaaagcag tcggagaagc
    24061 aaatggtaat gctaaagcgc aagcctttga cctggttcat gaattgtcaa tcgtagctca
    24121 gtctatcgaa tcaactcttt cagagaaaga aaccattgaa gccaaggttc gtgaacttct
    24181 tgaaacaact cgtaacgcct tttacatcgg acgtggtcaa gattactacg tagccatgga
    24241 agcaagtctc aaactcaaag agatttctta tatccagtgt gaaggttttg cggcaggaga
    24301 actcaagcac ggaaccattg ccttgattga agaaggaaca cctgtcttgg ctctcttgtc
    24361 agatccagtc cttgccaacc acactcgtgg aaatatccaa gaggtggcag cccgtggtgc
    24421 taaggtcctc actatcgcag aagaaaatgt tgctaaagat accgacgata tcgtccttac
    24481 gactgtacac ccttacctct caccaatttc aatggtcgta ccgacgcaat tggttgctta
    24541 ctttgcaacc ctccaccgtg gcctcgatgt ggataaacca cgtaaccttg ctaaatcagt
    24601 aacggtagaa taagctaaaa aagtctagtt atctaggctt tttctaatga gcaaattggt
    24661 tgcttgtact caagattcgt gttagaataa tttttcaaat tgaaggacag agatagacaa
    24721 ggagaatcac aatggtagaa ttgggaattt caacatttgg ggaaataacg gagcttgaag
    24781 ggactggaca aacttacagt catgctgaac gcattcgcca gttggtggca gagattgagc
    24841 tggctgacaa ggttggtttg gacgtatatg ggattggcga gcaccatcgg gcggattttg
    24901 cagtatcagc cccagagatt gtcctggccg ctggggcagt caataccaag aaaatccgtt
    24961 tgaccagtgc agtcagcatt ctgtcaagca tggatccgat tcgtttgttc caacagtatg
    25021 ccactatcga tgctttgtca aatggacgat cggagattat ggctggaagg ggctctttca
    25081 cggaatcttt ccctctgttt ggttatgact tgaaagacta cgactctctt tttgatgaga
    25141 aattagactt gcttcagtta gtcaatgaaa agaccaagtt agactggcaa ggtcgattga
    25201 ctcaaacgat tgctggtaaa gaagtttatc ctcgtccagt tcaggacaaa ttgcccttgt
    25261 ggatagctac aggtggtcat gtcgaatcaa cagtgaagat tgctcaggct ggtctaccga
    25321 ttgtatatgc tattattggt ggtaatccac gttattttaa aaagttgatt caggcttatc
    25381 gtgagattgg aagcgaagcg ggccatgctg acaaagactt gaaagtggga gcccattctt
    25441 gggggtggat tgcggaagat ggtgagcagg cggtgaaaga ttatttccat ccgactaagc
    25501 aagtggtgga tgctatttcc aaagaccgtc cgcactggca ggaattgcgt tatgagcaat
    25561 atttggagca ggtagggcca aatggcgcca tgtttgttgg caatccagat caggtggccg
    25621 aaaaattgat tcgcatgata gaggatttag gattggaccg cttcatgctt catctaccgc
    25681 ttggttctat gcctcatgac caggttctga gagctattga actcttcgga acacaagttg
    25741 cacccaaagt acgagcttat tttgctatga aagaggctta ataaaaaatc ctaatcaagt
    25801 ttattaggac aacaaatatt gtacaaaaat taatcccccg agctataatg cttgggggat
    25861 ttttctatag gagggctagt ttagttctct tttttatttt ttagtaagaa accgagacca
    25921 aggagcgcaa ggaggctgat tcctgcaaat aggagtttgt tttcgttttt gattcctgta
    25981 tttggaagtt cagcttgttt atctggggtt gcaggtatat tttccttgct agagttttct
    26041 accgattcgt ttcgaaccgc ttcttttaca gatgcttctt gtgcttcttg tgctggttgt
    26101 tcagcttgtg aatcagctgt agcttggcta ggtttatttt ccgcatcagc tactttggca
    26161 tctggtttag tagaatcagg tctagcttct ggagctgggt cttgatgtgc agggtgagaa
    26221 gcttcatttt gatgttcagg cttggaaggg gttgagtctg gtttctcttc tgcagttgac
    26281 tcatggctag ttccattttg agagactcga agaacagtag ctgtaagggc attcaatttc
    26341 aagccttttt cagtccattc aagtcctttc gggttggcaa ttccgactga tcctgcttgg
    26401 ttttcatctg ccaaaacttc cgcatttctt agatgtgcaa aggcagttcc caaattaaat
    26461 tcgcgagctt tttcatccgc attgacaaag actgcgtaga tatcaccgtt tggagcagtg
    26521 atttggtagc caatcactac atcctctttt tccacaccat tttggcctgg gacagtgatg
    26581 aggtggacac ggtctttgat atcttgaaga ctcttaagtc ggaaggcatc tgtagattga
    26641 cgaagggcaa tcaaaccttt catatagtca cggctcttga cattttcagg ataagcttta
    26701 ccatctgtag ccttagtcca gtcaaacttg ttgactgcgt cgctagaatc gtaagaatca
    26761 tggatgaagt aaggatagtc aaatgggttg ccgtccttat cacgcaacaa gtgagatttg
    26821 tttggaacct tatcctctgc tactggagtc ttgtaggctg ggtcacggaa ttgtttagta
    26881 cgtccatatt cctgaccgga gtggataaat ggagttcctt gagctgtcaa gaccatgaga
    26941 tttccaagtc gtaaacgacg gtggatttca gcatagttct cagccttgct tgggtctttt
    27001 ttgatagact gggcaatgat gtcaaagagg gtcaagttat catgggctgc gatgtattgg
    27061 atgacatctc cagggctgtc agcttcaaag ttagttggtt gagcaatgag atttttaaag
    27121 atggtgttga catcacgctt gccacctgtg ataaaggcag gttgaccttc gtttggataa
    27181 ccagatttga ggttgttacg gatgtcatct gaaaagacag cgacagtatc ggtatgtttc
    27241 atccaatctt ggtcagcagc cttagtaggc atgttttcat caccggcata ggttctccaa
    27301 ccttcaccaa gcatgatgag gtttggattg agggcgcgtg cagccttgta agcttcttcg
    27361 atagaagcgg cgtcatggtc tcccatcata tcgaagcgga agccatccac tttgtaggta
    27421 tcaactaggt atttgataga gtcaattagg agccgtttgg tcatatggtg ggttgtcccc
    27481 aagcgtccac caccaaagct agttcgaggt gtgccatcgg catccataaa gtggtagtag
    27541 tttggttcca aatcttcaaa gagatcgact ttggctgtgt ggttataaac gacatctagg
    27601 atagctccca taccacgttt gtggatttcg ttgatgaggt ttttaaattc tgcgattcgt
    27661 ttttctggat tcttaggatc gcttgagtac ataccagtca aggagaagta gttttgaggg
    27721 tcatatcccc agttgtagtt gctgttgctt gaagcgtagt cagacaagcg ttcatggttt
    27781 ttcaattcat tgacaaagta gtaagacaag actggaagga gctggatatg ggttacaccc
    27841 aagtctttga gatagtctag tttttcaatg aaggcttcaa aagtcccaaa tggtttggtc
    27901 aagtcttttg caatggcagg atctgaagtg aaatcacgca catgagcttc gtagataacg
    27961 gcgtcttcac gagtcttgaa attgtgaatc ttaccataag tcaagtcttg aggtccgagt
    28021 ttagctggat ctacaaaggc ggctttagcc actttatggg catcgtcaat cttggaatcg
    28081 tcgctattcc aagcagcaag agatttagcg taaggatcga gtgcaagaac agttttacct
    28141 tgacgctcga tttggtattg ataatagtag ccagtgaaat ctgtgattcc gagtttgttt
    28201 gtgctgtcta gagtttgttt ccaagttcct ctttcccctt tttcaagagc gacagttcca
    28261 actactttgt cagggtcatt cttgtcgtag acaacaacag aaaccttatc agcacttggt
    28321 gaccaaaggg tcaaatcaac ttgttttcct tcttctttta ggtcagctcc cagtttgcca
    28381 tcatagctgt atgtctcatc tttcaggcgc cagcttgttt tggtagtgaa ttggtcggaa
    28441 ttgtagctaa cagtataagg atgttttgtg tcagagaaat ctccgctgta ggtcactttc
    28501 ttaccagctt catcgattgc aacatcggta atagttacct tgtttcctag gtgattagtg
    28561 atgttggagt gtttgaggat atcttctttt ttagcaccga caagtgttga aaagctactt
    28621 tcaatgctag aagtgcctac gtgttgggct cctgtcatac ggatatcatg gacatagtat
    28681 ggatttgtgt aaatcgattc atcatcgtct tttaggaaaa tttggctatg atttttcaaa
    28741 tctgtgaact tataattttc tttacggatt ttcacgtcgt ctccttgttt gctctcatct
    28801 agtaataaaa atccaaattc tcttgcggct tcattaagag gaatgtcgat atagcggcca
    28861 tatttgcctg tagccgtaaa gtctgttccg tcaggccatt gagcgctact tggatttttt
    28921 acatctcccc agtaccagag agatttcttg tcatagttgc catctgtgcg gtagtagttg
    28981 acgcgaacag ttcctgcagg ctgtggctcg taagagaaaa ccttgtaatc ttggtctaac
    29041 caagcctcgt tcatttttgg aactagtttt tctacagatt tatcgccggt tagatttttt
    29101 ccagctgtat tgttgatgag gaagctaatt ttcttggctt gttctccctt taatttgaca
    29161 tctaggtaat agccgtagtc atctttcttg gcatccttga aggacaaagc tccgtttggc
    29221 cagttttcag atggtttttc aacatcgtcc caagtccata gtccttgagc atccttgttt
    29281 tcttcaggaa gttttttgac atggatacgg aagtagttat cttcgatggg ctcttctgcc
    29341 ttagtttcag ttgttactgg actagtagaa gtagttggct ctgttgcagg tttttcttct
    29401 gttttctcta gggaagcgtt tgcatttcta ggtgaagaaa tatcactttc gttcttacca
    29461 gagccagctg ctgtatcagt aagaggttgg gcaagggtgg ttgtatttct gttgttgggt
    29521 tcgttagtgg ttggtgtact ttcgtcggat gagatagttg gtgtagccat ggcaagcaag
    29581 acaaggcttg cgccgataag gacagaacca gttccatttt tgagggaacg gatgctgtag
    29641 accatttttt tctcagtgtg agatggtgtt tttctcataa tgattctcca atcaataaat
    29701 ttctatatca gtatagcatg tagtaaaaca atatgcaagc gttttctttg atttgtgaaa
    29761 aaaattctta cttttgagaa gttttctgta ctattttata tatcagtata aatgacggag
    29821 ataaaaatgt cacataagcc aagccgtatt attaggaaga tgatgtgttc ccagctattt
    29881 ttattcagaa attgatctct aacattacca ataaaaaaga aaaatatctt gacaagcaag
    29941 ggaaaatttt gttacaataa tagacggtac tttttacttt tggtctctca agagtgtaca
    30001 gggacgtgct gacaaatgtt gcaaaagtac acacagatga tatctgtcac caagtgtatc
    30061 atcaccaaaa ataaaaaaac acaggagaat gtagatgcct acaattaacc aattggttcg
    30121 caaaccgcgt aaatcaaaag tagaaaaatc taaatcacca gctttgaacg ttggttacaa
    30181 tagtcataaa aaagttcaaa caaacgtttc ttcaccacaa aaacgtggtg ttgcaactcg
    30241 tgttggaaca atgacaccta aaaaacctaa ctcagccctt cgtaaattcg ctcgtgtacg
    30301 tttgagcaac cttatcgaag ttactgccta catcccaggt atcggacaca acttgcaaga
    30361 gcacagcgtg gtgcttcttc gcggtggacg tgtaaaagac cttccagggg tacgttacca
    30421 tatcgtccgt ggtgcacttg atactgcagg tgttaacgat cgtaaacaag gccgttctaa
    30481 atacggtact aaacgtccaa aagcataagg aaaggggata aagagaaatg agtcgtaaaa
    30541 atagagctcc aaaacgtgac gtattgccag atccgctata caattcacaa ctagttactc
    30601 gtcttatcaa ccgcgttatg cttgatggta aacgtggtac tgctgcttca atcgtttacg
    30661 gtgcttttga gcaaatcaaa gaagctactg gcaacgatgc acttgaagta tttgaaacag
    30721 ctatggaaaa catcatgcct gtacttgaag tacgtgcacg tcgtgttggt ggttctaact
    30781 accaagtccc agttgaagtt cgtccagaac gtcgtacaac acttggactt cgttggttgg
    30841 taacaatcgc tcgtcttcgt ggtgaacaca caatgcaaga ccgtcttgca aaagaaatct
    30901 tggatgctgc taacaacact ggtgcagcag ttaagaaacg tgaagatact caccgtatgg
    30961 ctgaagctaa ccgtgcattc gcacacttcc gttggtaaga taggatgcga aagcgttaag
    31021 aaagtcccag agaaaatagg gaatcgaagc aggttgcggt tgcaaccaat gagattcatc
    31081 tttttctcca gacttttagc ttgagctcaa ctaaatcatg atgctaggca cggtaaggat
    31141 gcaaggtgaa aataggaaac tgacgcagta ttcaacgaat acaaggagtt ttatcttttt
    31201 cacgcagcat cccgttccag ctcacatcgg ctaactaact ttagcctggg ttcaaattag
    31261 ctaaatcgat tagtattagc tataactcag cttaccatct cgtaagttga aaccaacaat
    31321 agcatgaaaa cattgagaac gggtaggtcc tgcctatccg tttttattaa aatcgtgtta
    31381 taatagaata gaaatcaaaa ataaatagga gaaacaaacc tcatggcacg cgaattttca
    31441 cttgaaaaaa ctcgtaatat cggtatcatg gctcacgtcg atgccggtaa aacaacaact
    31501 actgagcgta ttctttacta cactggtaaa atccacaaaa tcggtgaaac tcacgaaggt
    31561 gcgtcacaaa tggactggat ggagcaagag caagaacgtg gtatcacgat cacatctgct
    31621 gcgacaacag ctcaatggaa caaccaccgc gtaaacatca tcgacacacc aggacacgtg
    31681 gacttcacaa tcgaagtaca acgttctctt cgtgtattgg atggtgcggt taccgttctt
    31741 gactcacaat caggtgttga acctcaaact gaaacagttt ggcgtcaagc aactgagtac
    31801 ggagttccac gtatcgtatt tgccaacaaa atggacaaaa tcggtgctga cttcctttac
    31861 tctgtaagca cacttcacga tcgtcttcaa gcaaatgcac acccaatcca attgccaatc
    31921 ggttctgaag atgacttccg tggtatcatt gacttgatca agatgaaagc tgaaatctat
    31981 actaacgacc ttggtacgga tatccttgaa gaagacatcc cagctgaata ccttgaccaa
    32041 gctcaagaat accgtgaaaa attgattgaa gcagttgctg aaactgacga agaattgatg
    32101 atgaaatacc tcgaaggtga agaaatcact aacgaagaat tgaaagctgg tatccgtaaa
    32161 gcgactatca acgttgaatt cttcccagta ttgtgtggtt cagccttcaa aaacaaaggt
    32221 gttcaattga tgcttgatgc ggttatcgac taccttccaa gtccacttga catcccagca
    32281 atcaaaggta ttaacccaga tacagacgct gaagaaactc gtccagcatc tgacgaagag
    32341 ccatttgcag ctcttgcctt caagatcatg actgacccat tcgtaggtcg tttgacattc
    32401 ttccgtgttt actcaggtgt tcttcaatca ggttcatacg tattgaatac ttctaaaggt
    32461 aaacgtgaac gtatcggacg tatccttcaa atgcacgcta acagccgtca agaaatcgac
    32521 actgtttact caggtgatat cgctgctgcc gttggtttga aagatactac aactggtgac
    32581 tcattgacag atgaaaaagc taaaatcatc cttgagtcaa tcaacgttcc agaaccagtt
    32641 atccaattga tggttgagcc aaaatctaaa gctgaccaag acaagatggg tatcgccctt
    32701 caaaaattgg ctgaagaaga tccaacattc cgcgttgaaa caaacgttga aactggtgaa
    32761 acagttatct caggtatggg tgaacttcac cttgacgtcc ttgttgatcg tatgcgtcgt
    32821 gagttcaaag ttgaagcgaa cgtaggtgct cctcaagtat cttaccgtga aacattccgc
    32881 gcttctactc aagcacgtgg attcttcaaa cgtcagtctg gtggtaaagg tcaattcggt
    32941 gatgtgtgga ttgaatttac tccaaacgaa gaaggtaaag gattcgaatt cgaaaacgca
    33001 atcgtcggtg gtgtggttcc tcgtgaattt atcccagcgg ttgaaaaagg tttggtagaa
    33061 tctatggcta acggtgttct tgcaggttac ccaatggttg acgttaaagc taagctttat
    33121 gatggttcat atcacgatgt cgactcatct gaaactgcct tcaagattgc ggcttcactt
    33181 tcccttaaag aagctgctaa atcagcacaa ccagctatcc ttgaaccaat gatgcttgta
    33241 acaatcactg ttccagaaga aaaccttggt gatgttatgg gtcacgtaac tgctcgtcgt
    33301 ggacgtgtag atggtatgga agcacacggt aacagccaaa tcgttcgtgc ttacgttcca
    33361 cttgctgaaa tgttcggtta cgcaacagtt cttcgttctg catctcaagg acgtggtaca
    33421 ttcatgatgg tatttgacca ctacgaagat gtacctaagt cagtacaaga agaaattatt
    33481 aagaaaaata aaggtgaaga ctaatccgtc ctcactctag aaggaagtca cttagtggct
    33541 tccttttgtc tttagaaaat acctctaaat atggtaaaat agtagaagaa taatgtgagg
    33601 aaaatgaatg tcaaatagtt ttgaaatttt gatgaatcaa ttggggatgc ctgctgaaat
    33661 gagacaggct cctgctttag cacaggccaa tattgagcga gttgtggttc ataaaattag
    33721 taaggtatgg gagtttcatt tcgtattttc taatatttta ccgattgaaa tctttttaga
    33781 attaaagaaa ggtttgagcg aagaattttc taagacaggc aataaagctg tttttgaaat
    33841 taaggctcgg tctcaagaat tttcaaatca gctcttgcag tcctactata gggaggcttt
    33901 ctctgaaggt ccatgtgcta gtcaaggttt taagtccctt tatcaaaatt tgcaagttcg
    33961 tgctgagggt aatcagctat ttattgaagg atctgaagcg attgataagg aacattttaa
    34021 gaagaatcat cttcctaatt tagccaaaca acttgaaaag tttggttttc caacttttaa
    34081 ctgtcaagtt gagaagaatg atgtcctgac ccaagagcag gaagaggcct ttcatgctga
    34141 aaatgagcag attgttcaag ctgccaatga ggaagcgctc cgtgctatgg aacaactgga
    34201 gcagatggca cctcctccag cggaagagaa accagtcttt gattttcaag cgaaaaaagc
    34261 tgcagctaaa cccaagctgg ataaggcgga gattactcct atgatcgaag tgacgacaga
    34321 ggaaaatcgt ctggtatttg aaggggttgt ttttgatgtg gagcaaaaag tgactagaac
    34381 aggtcgtgtt ttaatcaact ttaaaatgac ggactatact tcaagttttt ctatgcaaaa
    34441 gtgggttaaa aacgaggaag aggcccagaa gtttgacctc atcaagaaga attcttggct
    34501 ccgagttcga gggaatgtgg agatgaataa cttcacacgc gatttgacta tgaacgtaca
    34561 ggatctgcag gaagttgttc actatgagcg gaaggatttg atgccagaag gtgagcgtcg
    34621 ggttgagttt catgctcata ctaacatgtc gactatggat gctttgccag aggtcgaaga
    34681 gattgttgca acagctgcta agtggggaca caaggcggtt gctatcacag accatgggaa
    34741 tgtccagtcc tttccacatg gctataaggc ggctaagaaa gcgggaatcc agctgatcta
    34801 tgggatagaa gccaatatcg tggaggaccg tgtccctatc gtctataacg aagtggagat
    34861 ggacttatca gaagcaacct acgtggtctt tgacgtggaa acgacgggac tttcagctat
    34921 ctataatgac ttgattcagg ttgcggcctc taagatgtac aaggggaatg ttattgctga
    34981 atttgatgaa tttatcaatc ctgggcatcc cttgtcagct tttactacag agttaactgg
    35041 aattacagat gatcatgtca aaaatgccaa accactagaa caagttttgc aagaattcca
    35101 agaattttgc aaggatacgg tcctagttgc ccacaatgct gcctttgacg ttggctttat
    35161 gaatgctaat tatgagcgtc atggtcttcc aaagattagt cagccagtta ttgatacgct
    35221 ggagtttgct agaaacctct atcctgagta taaacgccat ggtttggggc ctttgaccaa
    35281 gcgttttggt gtggccttgg aacatcacca catggccaac tacgatgcgg aagcgactgg
    35341 tcgtctgctt ttcatcttta tcaaagaggt agcagaaaaa catggtgtga ccgatttagc
    35401 tagactcaac attgatctaa tcagtccaga ttcttacaaa aaagctcgga tcaagcatgc
    35461 gaccatctat gtcaagaatc aggtaggtct aaaaaatatc tttaagctgg tttccttgtc
    35521 taataccaag tattttgaag gagtgccacg gattccgaga acggttctag atgcccatcg
    35581 agagggcttg attttaggtt cagcctgttc agagggtgaa gtttttgacg tggtcgtttc
    35641 tcaaggtgtg gatgcggcgg ttgaggtggc caagtattat gactttatcg aggtcatgcc
    35701 accggctatc tatgcgccct tgattgctaa agagcaggtc aaggatatgg aggaactcca
    35761 gaccattatc aagagtttga tagaggttgg agaccgcctt ggcaagcctg ttttggctac
    35821 gggaaatgtt cactatatcg aaccggaaga agagatttat cgtgaaatta tcgtccgtag
    35881 tttgggacag ggtgcgatga ttaaccgaac tatcggtcat ggtgaacatg cccaaccagc
    35941 accacttcca aaggctcatt ttcgaacgac taatgagatg ttggatgaat ttgccttttt
    36001 gggagaggaa ctggctcgta aactggttat tgaaaacacc aatgccttgg cagaaatatt
    36061 tgaacccgtt gaagtcgtta agggtgactt gtatacgcct ttcatcgaca aggctgaaga
    36121 aacagttgct gagttgacct ataagaaagc ttttgagatt tatggaaatc cgctgccaga
    36181 tattgttgat ttgcggattg aaaaagaatt aacatccata ctggggaatg gatttgctgt
    36241 gatttatctg gcatcgcaga tgctggtgca acgttctaat gaacggggtt atttggttgg
    36301 ttctcgtggg tctgtcggat ctagtttcgt tgcgaccatg attggaatta cggaggtcaa
    36361 tcctctctct cctcactatg tctgtggtca gtgtcagtac agtgagttta tcacagatgg
    36421 ttcgtacggt tcaggatttg atatgcccca taaggactgt ccaaactgtg gtcacaaact
    36481 cagtaaaaac ggacaggata ttccgtttga gaccttcctt ggttttgatg gggataaggt
    36541 tcctgatatt gacttgaact tctcgggaga agatcagcct agcgcccact tggatgtgcg
    36601 tgatatcttt ggtgaagaat atgccttccg tgcgggaaca gttggtacgg tagctgccaa
    36661 gactgcctat ggatttgtca agggttacga gcgagattat ggcaagtttt atcgtgatgc
    36721 agaagtagaa cgcctcgctc aaggagcggc gggtgtcaag cggacaacag gccaacaccc
    36781 ggggggaatc gttgttattc cgaactacat ggatgtctac gattttacgc ctgtccagta
    36841 tccagcagat gatgtcacgg ctgaatggca gaccactcac tttaacttcc acgatatcga
    36901 tgagaacgtc ctcaaactcg atgtactggg acatgatgat ccgaccatga ttcgaaaact
    36961 tcaggatttg tctggtattg accctaataa aattcctatg gatgacgaag gcgtgatggc
    37021 actcttttct gggactgatg tgctaggggt aacacctgaa caaattggaa cgcctacggg
    37081 tatgttgggg attccagagt ttggaacaaa tttcgtacgt ggaatggtag acgaaaccca
    37141 tccgacaacc tttgcggaat tgcttcagct gtctggtctg tcccacggta ctgatgtttg
    37201 gttggggaat gctcaggatc tgattaagca aggaatagcg gacctatcga ctgttatcgg
    37261 ttgtcgggac gacatcatgg tttacctcat gcatgcgggt ctggaaccta agatggcctt
    37321 taccattatg gaacgggtac gtaagggttt gtggctaaag atttcagaag aggagagaaa
    37381 tggctatatc gaagcaatga aggctaataa ggtgccagag tggtatatcg aatcctgtgg
    37441 gaaaattaag tacatgttcc ctaaggccca tgcggcagcc tacgttatga tggccttgcg
    37501 tgtagcttac ttcaaggttc accatcctat ttattactac tgtgcttact tctccattcg
    37561 tgctaaggct tttgatatca agaccatggg tgcgggcttg gaggtcatca agcgcagaat
    37621 ggaagaaatc tctgaaaaac ggaagaacaa tgaagcctct aatgtggaaa tcgatctcta
    37681 tacaactctt gagattgtca atgagatgtg ggaacgaggt ttcaagtttg gtaaattaga
    37741 tctctaccgt agtcaggcga cagagttcct catcgacggg gataccctta tcccaccatt
    37801 tgtagcaatg gatggtctgg gagagaacgt tgccaagcaa ctggtgcggg cgcgtgaaga
    37861 gggagaattc ctctctaaaa cagaactacg caagcgtggt ggactctcat caaccttggt
    37921 tgaaaagatg gatgagatgg gtattcttgg aaatatgcca gaggataacc agttgagttt
    37981 gtttgatgag ttgttttaaa aaattgctta ataatctatt aaaagaggct aacgtatatc
    38041 caatagattt acattagctt tcttttttgt taaaatagtc tatggaaaga gggtgagagt
    38101 atgtcaaaga tgagtataag catccgtctg gatagtgagg ttaaggagca ggcccaacag
    38161 gtgtttagta atctgggaat ggatatgaca acagctatta atattttcct tcgtcaggca
    38221 attcaatatc agggattacc ttttgatgtt agactagacg aaaatcggaa gttgctccaa
    38281 gcgttaacgg atttagacca aaatcgtaat atgagccagt cttttgaatc agtctcagat
    38341 ttgatggagg acttacgtgc ttaagattcg ttatcataaa cagtttaaaa aagattttaa
    38401 gttggctatg aagcgtggtt tgaaggcaga attattagaa gaagttttga attttctggt
    38461 tcaagaaaaa gaacatcctg ccagatatcg tgatcattca ttgacggcat ccaagcattt
    38521 tcaaggagtt cgtgaatgcc atacccagcc agattggctt ttggtttata aagtagacaa
    38581 gtcggaattg attttaaatt tgctgaggac aggcagtcac agtgatttat tttaatctat
    38641 tttaaggggg ttctcatgaa actaagaata tttgcggaag ataagccggc taagaaggta
    38701 tttgaatatc aattagaact tgctgatcgt acaattcttc tatcgacagc actcttgtca
    38761 ggtgctattg ctttagcagg aatcttttct gctttgaaag aaaaataaaa atagaaaaga
    38821 gaaaacagaa tggttttacc aaattttaaa gaaaatctag aaaaatatgc gaaattgttg
    38881 gttgcgaacg gaattaacgt gcaacctggt cacactttgg ctctctctat tgatgtggag
    38941 caacgtgaat tggcacatct aatcgtgaaa gaagcttatg ccttgggtgc gcatgaggtc
    39001 atcgttcagt ggacagatga tgtgattaac cgtgagaaat tcctccatgc cccgatggag
    39061 cgtttggaca atgtgccaga atacaagatt gctgagatga actatctttt ggagaacaag
    39121 gctagccgtc ttggggttcg ttcatctgat ccaggtgcct tgaacggagt ggacgctgac
    39181 aagctttcag cttctgctaa agctatggga cttgccatga agcctatgcg tatcgcaact
    39241 caatctaaca aggttagctg gactgtagca gccgctgctg gacttgagtg ggctaagaaa
    39301 gtcttcccaa atgctgcgag cgacgaagaa gcagttgatt tcctttggga tcaaatcttc
    39361 aaaacttgtc gtgtctacga agcagatcct gttaaggctt gggaggaaca tgcagccatt
    39421 ctcaagagca aggccgatat gcttaataag gagcaatttt cagcccttca ctacacagcg
    39481 ccaggaacag atttaacact tggtttgcca aagaaccacg tttgggaatc agctggtgct
    39541 gtcaatgcac agggcgaaga attcttgcca aatatgccga cagaagaggt cttcacagcg
    39601 cctgacttcc gtcgtgcaga tggttatgtc acttctacaa aaccgcttag ctacaacgga
    39661 aatatcattg aaggcattaa ggtgaccttt aaggatggac aaatcgtaga tatcactgct
    39721 gagaagggtg atcaggttat gaaagacctt gtctttgaaa atgcgggtgc gcgtgccttg
    39781 ggtgaatgtg ccttggtacc agatccaagt ccaatttctc agtcaggcat tacctttttt
    39841 aacacccttt tcgatgaaaa tgcgtcaaac cacttggcta tcggtgcagc ctatgcgact
    39901 agcgttgttg atggagcgga gatgagcgaa gaggagcttg aagctgcagg gcttaaccgt
    39961 tcagatgttc acgtagactt tatgattggt tctaaccaaa tggatatcga tggtattcgt
    40021 gaggatggaa cgcgggtacc tcttttccgt aatgggaatt gggcaaatta aggagataat
    40081 atgttaggaa gtatgttcgt tggtctccta gtgggatttt tagcaggtgc tatgaccaat
    40141 cgtggagagc gaatgggatg ttttggaaaa atgtttctcg gttggatcgg agcctttcta
    40201 ggtcacttgc tctttggaac ttgggggcca gttttatcag gaacagctat tatcccagcg
    40261 attttaggag ccatgattgt tttagctatt ttttggagac gaggaagtta atttcctaaa
    40321 tctgatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaagc
    40381 actgctttga ggttgcagat agaactgacg aagtcagcta aaaacactgt tttgaggttg
    40441 cagatagaac tgacgaagtc agctaaaaac actgttttga ggttgcagat agaactgacg
    40501 aagtcagtaa catatatacg gcaaggcgac gttgacgcgg tttgaagaga tttttgaaga
    40561 gtatgaaacg aaaaggaggt tggtcattgt actagcctcc ttttgatatg atataatagt
    40621 tctatgagat tagataaatt tttagttgcc tgtgcggtgg gaagtcggac tgaggtcaaa
    40681 aacttgctca aggctgggcg cgtgactgta aatggtaaaa aagaaaaatc agctaaattg
    40741 cagattgatg aaaaaataga tgagattcgc tttgatgggc aagtgttgga gtatgaagag
    40801 tttgtctact acatgatgaa caagcccaaa ggagttatct cagcgactga ggatcccaag
    40861 cacagaaccg ttctggactt gttggatgac ttggcgcgga gtaaggaagt ttttccagta
    40921 ggacgcttgg atattgacac gcatggtctt ttgctcttga ccaataatgg tcagctggct
    40981 catgttcttc tttcgcccaa gcgtcatgtg gacaagactt atcaggctca ggtcaaggga
    41041 attatgaccc aagaagatgt ggagacattt atcaagggca ttccgctcaa agactttacc
    41101 tgtcagcccg ctagactgga gattctttcc acagatgcag aaaagaatca gagccaaatc
    41161 cgtgtgacca ttgcagaagg gaagtttcat cagatcaagc gtatggtggg ctactgtggc
    41221 aaggaagtgg tggacttgca acgattgact atgggaactt tagtattaga tgagaacctg
    41281 gaacgagggg aatggcgtcg cttgaccaag gaagaattag aaattctccg cgctaatatt
    41341 atttaattta gtttaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
    41401 ctgtacttga gtacggcaag gcgacgttga cgtggtttga agagattttc gaagagtata
    41461 aattcgaaaa aggtgaggga caatgtcctc gccttttatg ttttttagtt gcttcctttg
    41521 tgaaaagagt tataatagac tgtagaataa aaggaggaat ctatgaacgc gattcaagaa
    41581 tcatttactg ataaactatt tgccaactat gaagcaaatg taaaatacca agcgattgaa
    41641 aatgctgcca gccacaacgg aatttttgca gctctggaat gtcgccaaag ccatgtagac
    41701 aacacacctg ttttctcatt ggatttaacc aaggacaagg tcactaacca gaaagcgtct
    41761 ggtcgttgct ggatgtttgc ggctctcaac accttccgcc acaaactcat ctcgcaatac
    41821 aaattggaga actttgagtt gtcacaagcc cacactttct tctgggataa gtatgagaaa
    41881 tcaaactggt tcttggagca agtcattgcg acttcagacc aagaattgac tagccgcaag
    41941 gttagcttct tactccaaac acctcaacaa gatggcggtc aatgggatat ggtcgtttcc
    42001 ctctttgaaa aatacggtgt cgtgcctaag tcagtttatc ctgagtctgt ttcatctagc
    42061 agcagtcgtg agctaaatgc gatccttaat aaattgcttc gtcaagatgc tcaaatcttg
    42121 cgtgatttgc ttgtttctgg tgcagatcaa gcgactgttc aagctaagaa agaagacctc
    42181 ttgcaagaaa tctttaactt tcttgctatg tcattaggac ttccaccacg caagtttgac
    42241 tttgcttatc gcgataaaga taacaactat aaaagtgaaa aaggaatcac accacaagag
    42301 ttttacaaga aatatgtcaa tcttccttta gaagactacg tttctgttat caatgctcca
    42361 actgctgata aaccttacgg aaaatcttac acagttgaga tgttggggaa tgtggttggt
    42421 agccgtgcag ttcgctacat caacgttcca atggagcgct tgaaagaatt ggcgattgcc
    42481 caaatgcaag caggtgagac tgtttggttt ggttctgatg tcggccagct cagcaaccgt
    42541 aaggctggca tccttgcgac agatgtttat gactttgaat caagcatgga cattaaactt
    42601 actcaagaca aggctggacg tttggactat agcgaaagct tgatgaccca cgccatggtc
    42661 ttgacaggtg ttgacttgga cgaaaatggt aaatcaacca agtggaaggt tgaaaactca
    42721 tggggagaca aggtcggtac agatggttac tttgttgcct cagacgcttg gatggacgaa
    42781 tacacatacc aaatcgttgt tcgtaaggaa ttgctgacag cagaagaaca agctgcctat
    42841 ggagcagaac caatcgtact tgcaccatgg gatccaatgg gagccttggc tgaataaaag
    42901 catagaaaaa aggaatcaga ttttagaacc tggttccttt ttagttgctt gattacatga
    42961 tgtgaagaac atgtgccaca atacccactg cgaagagggc aaggataata gtgattggag
    43021 atactttttt cttaagtaag tacatgcaaa gtaaagtaag gagtagtcct gataatccag
    43081 gaatcaacat atccaagttt tgttggaaag tagtaacttt ttcaggagtt tgagacaatc
    43141 cttgtcctac ttgtgcgaat gcttcttgga tacctttaga cccttctggc aatttatccc
    43201 aatggatata agccttttca tctagttgaa ctttagaaac atcgaaagca aatttaatat
    43261 ttacccagcg ttgaacaagg acagcaagaa tgaacatccc aaggatagaa gctcctttag
    43321 tgatatcttg aaggatacca ccagacatat ctttagtgat ttctgatcca gccttgtatc
    43381 caatctcttg aacataccac aagaatgaca tacgaatcaa gttccatgca acaaagaaga
    43441 ggagtggccc caagatattg ccagtaaggg caagtgaagc accgagagat ccaaggattg
    43501 ggcgtactgt aaaccagaat actgggtcac cgataccagc aagaggtccc atcataccga
    43561 ttttaacccc ttggatagca gcgtcatcga tttccacacc gttagcacgt tcttcttcaa
    43621 gcgcaagagt aacccccatg actggagcag ctacgtatgg atgagtgttg aagaactcaa
    43681 ggtgacgctc aagagcagcg atttgatctt cttttttagt atagagtttt ttgatagctg
    43741 gaatgagtgt ataagcccag cccaagtttt gcatccgttc aaagttccaa gacccttgta
    43801 agaaggttga acgccaccaa acttttttac gatctgattt agttaattga agtttttcag
    43861 tcatgatgtt ttcagtcctt tcttatctta gtagtcttct aggatatcgc cgattgggtc
    43921 gttagaagtt gcggctcctc cgccaccatt tccaccagtt ttagaaaggt gaaggtagat
    43981 aagagcgata gcaacaccga tagcaccgaa tccgattaga gtaatatctg acacagcagc
    44041 aagaacgaaa ccaagagcga agaatggcca tacttcacga gttgccatca tgttgataac
    44101 catggcgtaa ccaacggcaa cgaccatacc accaccgata gccataccat ctttgagcca
    44161 gtctggcatg gcactaagga tactttgtac agtttcagtt ggtaccataa ggagaagagc
    44221 tgcaggaagc gcgatacgaa gtccttggaa aagtagcgca atgaaatgag cacgctccac
    44281 agcgccgaag tcaccttttt tagcggcagc atcagcagtg tgaaccaatc caactgaaat
    44341 tgtacgaaca atcatagtta agaatagacc agctacggca agagggatag caaccgcttg
    44401 ggcaacaccg ataccagtct tggtaaagtc accaccaaga accatgataa tggcagcagc
    44461 gacagaagca agtgcagcat caggagcgat agcagcaccg atatttgacc aaccaagggc
    44521 aatcatttga agcgatccac cgaggataat ccctgcttcc aagtgacctg ttacaagccc
    44581 aataagggta caggctacaa gtggttggtg aaattggaac tggtcgagga tgccttcaag
    44641 acctgcaaag aaggctacaa cgactactaa aaccatagaa ataatagaca tgtttaaaat
    44701 cctttcataa ataatggctt atttgacatt ggctttgtta atcaagtcaa acaaatcttt
    44761 tttagaatca tttggtactt tacggacatc aaattcaaca cccaagtcac gcattttttc
    44821 aaatgtagca acatcttctt tgtccataga caaaacggta ttgaccaatg ttttacctgt
    44881 tgagtgagcc atagaaccaa cgttaagagt cttgattggc acgccgcctt cgatggcacg
    44941 aagggcatct tgaggtgttt caaacaagat aagggcatgt gtttctccaa aacgtgggtc
    45001 ttttgaaatc tcaatcagtt tttgaattgg aaccacgtta gccttgacat tacctggagc
    45061 tgcttgttta atcaattctt tacgaaggtc gtctttagcc acgttatctg aagcaacgat
    45121 gatacgattt gcttttgaat ctggagtcca agcagttgca acctgaccgt gaagtagacg
    45181 tgtgtcaaga cgggcaagat tgattttcaa tttaccgtct ccgataacag ttccttctgg
    45241 gatagcagtt tgggcaactg gagcagctgc agcgcttgca acttcttcaa ctggatttag
    45301 ctcttctgga agagctttga tgccatcttt ggcttcttta atgatattag cagcgacttt
    45361 ttctacacct gcagcagcgt ccatgaggcg ctctgtgtag gcttgaatca acatcggtaa
    45421 gttaagtcct gtgatgatgg caaacttacg ctcaggattt tctcccatca cgcgactagc
    45481 ttggttaaat ggagaaccac tccaaaggtc agccaaaact agaacctcat cttctgcgtc
    45541 aaatgcagca acagcgttat taaacttagc gtatagatca tcaggacctt catttggcat
    45601 aaaggtcaca acttgaacct tttcttgttc accaaagatc atagatcctg actgatgaat
    45661 acccgcagca aattcgccgt ggctcgcaat aatgattccg atactcatta ttgtcattcc
    45721 tccttttttg ttttagtttt catttaagaa aactttaaga ctgtttaagt ataaaccgtt
    45781 ttcataaaaa aagcaactat ttatcataaa aaatt
//
LOCUS       DAVLTG010000011        43360 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLTG010000011 DAVLTG010000000
VERSION     DAVLTG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.011"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VYN12_000643"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VYN12_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1415077.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VYN12_000644"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VYN12_000644"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1415078.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VYN12_000645"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VYN12_000645"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1415079.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDEFVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VYN12_000646"
     CDS             complement(3790..5058)
                     /locus_tag="VYN12_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1415080.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VYN12_000647"
     CDS             complement(5178..5546)
                     /locus_tag="VYN12_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1415081.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VYN12_000648"
     CDS             complement(5539..5805)
                     /locus_tag="VYN12_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1415082.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VYN12_000649"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VYN12_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1415083.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIHDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VYN12_000650"
     CDS             complement(9373..9942)
                     /locus_tag="VYN12_000650"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1415084.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10014..11129)
                     /gene="ychF"
                     /locus_tag="VYN12_000651"
     CDS             complement(10014..11129)
                     /gene="ychF"
                     /locus_tag="VYN12_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1415085.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11213..11407)
                     /locus_tag="VYN12_000652"
     CDS             complement(11213..11407)
                     /locus_tag="VYN12_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1415086.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11472..12608)
                     /gene="dnaN"
                     /locus_tag="VYN12_000653"
     CDS             complement(11472..12608)
                     /gene="dnaN"
                     /locus_tag="VYN12_000653"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1415087.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12767..14128)
                     /gene="dnaA"
                     /locus_tag="VYN12_000654"
     CDS             complement(12767..14128)
                     /gene="dnaA"
                     /locus_tag="VYN12_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1415088.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14341..15099)
                     /locus_tag="VYN12_000655"
     CDS             complement(14341..15099)
                     /locus_tag="VYN12_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1415089.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15157..16338)
                     /locus_tag="VYN12_000656"
     CDS             complement(15157..16338)
                     /locus_tag="VYN12_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1415090.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16521..17000
                     /gene="rlmH"
                     /locus_tag="VYN12_000657"
     CDS             16521..17000
                     /gene="rlmH"
                     /locus_tag="VYN12_000657"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1415091.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17044..17117
                     /locus_tag="VYN12_000658"
     tRNA            17044..17117
                     /locus_tag="VYN12_000658"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17078..17080,aa:Arg,seq:tct)
     gene            17282..17407
                     /gene="comC"
                     /locus_tag="VYN12_000659"
     CDS             17282..17407
                     /gene="comC"
                     /locus_tag="VYN12_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1415092.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            17428..18753
                     /locus_tag="VYN12_000660"
     CDS             17428..18753
                     /locus_tag="VYN12_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1415093.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18750..19502
                     /locus_tag="VYN12_000661"
     CDS             18750..19502
                     /locus_tag="VYN12_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415094.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19554..19625
                     /locus_tag="VYN12_000662"
     tRNA            19554..19625
                     /locus_tag="VYN12_000662"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19587..19589,aa:Glu,seq:ttc)
     gene            19631..19704
                     /locus_tag="VYN12_000663"
     tRNA            19631..19704
                     /locus_tag="VYN12_000663"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19665..19667,aa:Asn,seq:gtt)
     gene            complement(19745..20287)
                     /locus_tag="VYN12_000664"
     CDS             complement(19745..20287)
                     /locus_tag="VYN12_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1415095.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20466..21233
                     /locus_tag="VYN12_000665"
     CDS             20466..21233
                     /locus_tag="VYN12_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1415096.1"
                     /translation="MIGISLIPALYNIIFLSSMWEPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGILENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21318..21998
                     /locus_tag="VYN12_000666"
     CDS             21318..21998
                     /locus_tag="VYN12_000666"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1415097.1"
                     /translation="MADGSRKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
     gene            complement(22099..24651)
                     /locus_tag="VYN12_000667"
     CDS             complement(22099..24651)
                     /locus_tag="VYN12_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1415098.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24713..26335)
                     /locus_tag="VYN12_000668"
     CDS             complement(24713..26335)
                     /locus_tag="VYN12_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1415099.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26541..27566
                     /gene="trpS"
                     /locus_tag="VYN12_000669"
     CDS             26541..27566
                     /gene="trpS"
                     /locus_tag="VYN12_000669"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1415100.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27718..29196
                     /gene="guaB"
                     /locus_tag="VYN12_000670"
     CDS             27718..29196
                     /gene="guaB"
                     /locus_tag="VYN12_000670"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1415101.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29247..30344)
                     /gene="recF"
                     /locus_tag="VYN12_000671"
     CDS             complement(29247..30344)
                     /gene="recF"
                     /locus_tag="VYN12_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1415102.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30347..30715)
                     /gene="yaaA"
                     /locus_tag="VYN12_000672"
     CDS             complement(30347..30715)
                     /gene="yaaA"
                     /locus_tag="VYN12_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1415103.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30874..32124
                     /locus_tag="VYN12_000673"
     CDS             30874..32124
                     /locus_tag="VYN12_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1415104.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32121..33404
                     /locus_tag="VYN12_000674"
     CDS             32121..33404
                     /locus_tag="VYN12_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1415105.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESVSQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIYDGDIVDFTIFPS"
     gene            33446..34267
                     /locus_tag="VYN12_000675"
     CDS             33446..34267
                     /locus_tag="VYN12_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1415106.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34278..34823
                     /gene="pgsA"
                     /locus_tag="VYN12_000676"
     CDS             34278..34823
                     /gene="pgsA"
                     /locus_tag="VYN12_000676"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1415107.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34820..35647
                     /locus_tag="VYN12_000677"
     CDS             34820..35647
                     /locus_tag="VYN12_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1415108.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKHGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35632..36471
                     /locus_tag="VYN12_000678"
     CDS             35632..36471
                     /locus_tag="VYN12_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1415109.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRIFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36464..37258
                     /locus_tag="VYN12_000679"
     CDS             36464..37258
                     /locus_tag="VYN12_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1415110.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37317..38135
                     /gene="mreC"
                     /locus_tag="VYN12_000680"
     CDS             37317..38135
                     /gene="mreC"
                     /locus_tag="VYN12_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1415111.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38135..38629
                     /gene="mreD"
                     /locus_tag="VYN12_000681"
     CDS             38135..38629
                     /gene="mreD"
                     /locus_tag="VYN12_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1415112.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38723..39901
                     /locus_tag="VYN12_000682"
     CDS             38723..39901
                     /locus_tag="VYN12_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1415113.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40125..40904
                     /gene="rpsB"
                     /locus_tag="VYN12_000683"
     CDS             40125..40904
                     /gene="rpsB"
                     /locus_tag="VYN12_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1415114.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40983..42023
                     /locus_tag="VYN12_000684"
     CDS             40983..42023
                     /locus_tag="VYN12_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1415115.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42269..42592
                     /gene="tnpB"
                     /locus_tag="VYN12_000685"
     CDS             42269..42592
                     /gene="tnpB"
                     /locus_tag="VYN12_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1415116.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKDFS
                     ITPQI"
     gene            complement(42733..42965)
                     /locus_tag="VYN12_000686"
                     /pseudo
     CDS             complement(42733..42965)
                     /locus_tag="VYN12_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            43131..>43360
                     /locus_tag="VYN12_000687"
     CDS             43131..>43360
                     /locus_tag="VYN12_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415117.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTG"
BASE COUNT        13573 a         7501 c         7976 g        14310 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagttttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcttcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattaatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aaattcatct tcctcttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatt ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccgatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacatgga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa atactaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttaaactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagccg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttaaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca tgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac ggggatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcgc gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agagaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaagtctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggggtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctacg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacgt caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aatagactgt aaaataccga tataatcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt ttttccaacc taattgacac catttattaa tttttagaca
    10021 ttaaagcgga attccatgat atcgccatct tgaacgatat attcttttcc ttcttcacgc
    10081 aagcgtccag cttcttttac ggccttttca gatccgtatt tcactagatc ttcatatgac
    10141 atggttactg cacgaataaa gcctttttca aagtctgagt ggataatacc agctgcttga
    10201 ggagccttca taccacgttt gaaagtccaa gcgcgaactt ctttttcacc agctgtgaag
    10261 taagttccca atccaagcaa gtggtaagct gcacgcgtca acttatctac acctgattct
    10321 gtcaaaccaa tggcttcaag aaactctttt ttatcttcat catccaattc agaaatttct
    10381 tcctcagcac gcgcagaaat aacgactact tcagcatttt ctgtcgctgc aaattcacga
    10441 atttgtttga catagtcgat agagtcaggt tctgaaacca catcctcgtc cacattagct
    10501 acataaagaa ctggtttagt cgtcaaaagg aaaagacctt tgacaacctt ttgttcctca
    10561 tctgtaaatt caatggtacg agctgatttc ccgtcttcta ggactggttt aatcttttga
    10621 agaacattga attctgctac tgattcttta tctttttgcg tacgtgccat cttttctaca
    10681 cgcgcatatc gtttgttcac tgattctaag tcagcaagaa ttaattccag attaattgta
    10741 tcaatatctg caagtggatc tacaaaggcg tcttcacgtc cttgctcgcg catcacattt
    10801 tcatcatcaa aagcacgaac tacgtgaaca atcgcatcta cttcacgaat attggccaag
    10861 aatttattcc ctagcccttc tccttttgaa gctcctttta caatccctgc aatatccgta
    10921 aattcaaatg ttgtgggaac tgttttttta ggagttatca tttcagttag tttttgtagg
    10981 cgttcatctg gaacttccac cattccaaca tttggatcaa tcgtcgcaaa tgggtagttt
    11041 gctgcctctg ctcctgcttt tgtaattgca ttaaatagtg ttgatttacc aacgtttggc
    11101 aaaccaacga tacctgctgt caaagccata tttctcattc tccgttttca tttcaatccc
    11161 taatattata acacaaaaag ggataaagcg ctaaccctct aactaagggt tctcagtcaa
    11221 taattttatt catttttcgc tcaaaatcat atcgccccat catgacaaca tgctcacaat
    11281 tactgcattt tattttgata tctgctccta cacgtgtaat ttcccaacga ttagcctttt
    11341 taccagtcga cttgattgta caagcgtgtg attttttcat ctcaacaaaa tttccaactt
    11401 gatacatact actctccttt tctttttcga ttatatcata aaagaggcga gccaggctca
    11461 acctctttca cttaatttgt acgaactggt gtaatgagct gcatgaagtc ttcgtcagta
    11521 tctgctggca caagagtaaa tggacgaaca gctgagataa agctaatggt caccttttcg
    11581 ctatttaaag ctttaagaga atcaatcaag taagttgggt tgaaactaat ggtcaaatct
    11641 tcaccagtaa cctgatcagt atcgatttct tcgtttactt taccaacttc tggagagtga
    11701 acatgggcgc taacaacccc atccttaatt tcaagtttca cagtaccatt ttgagtcgca
    11761 cttgataaaa gacgggcacg ctccattgac tggcgtaagt ttaccacatt aaaagtaata
    11821 gtagtgttaa agtctgttgg aatcaagcga tctgtatcag gatagtttcc ttctaggaga
    11881 cgagtataga agctaatatt ttcgcttcta aagaggattt ggttattggc aaagaaaatc
    11941 tctacagttt cgatatcatc tgtaaatacc gctgaaaatt cgcgtagaga acggctagga
    12001 attacgacat caaaatcatc actatttttt tcaagagtca attttttctg gcttaggcga
    12061 tgagagtctg ttgcaactgt ttttaactct ttgtgttgac tcaatacgaa gtggacacct
    12121 gttaaaatcg gacgactctc ttgtgtactt gcagcaaagg ctgtttcatt aataattttc
    12181 ttgagtaatt ttgtttcaag tattaaagga gtgcttgctg aaatttcttg gattcgtgga
    12241 tattgttcgc tatcttttcc ttttagggta atttctgatt tgccactggt taaaacaatt
    12301 tgattttgtt caatttcttt aaaatcaaga gtcacatcag gtaaactaga tactacattg
    12361 ataaagaaag aagcttcaag aaggatcgaa cctaaagaag taattaacaa accagcatct
    12421 tcattttttt gagaaataaa attttcaatt gaaatttgac catttgaacc aattaaagta
    12481 ataccttcat tggtcacgtc aatttttact gttgataaaa taggaatggc atttttagaa
    12541 ctaatagctc tcttagtagt atttaatgct tgtagaaata aatttttatt aattgaaaaa
    12601 tgaatcatgg attctccttt atttattttt agtattagaa agataatagt aataatagag
    12661 tctgtgaaat ctgtggaaaa cagcctttaa acaagtcata tcaagttttt tagcttgttt
    12721 aaaaaatgtg gataaaaaag ataaaaaact aaaagttatc cacaaattat ttgattttct
    12781 ttttgattga ttcaatttct aaacgtaaat tatcgtcttg atcaatcaaa gattttattt
    12841 tggcatgggc atgaatgact gtggtatgat cttttccccc aaattccttc ccaatttttg
    12901 gaagactatt atctgttagt tctctagata aatacatggc tacttgacgg gccaaaacaa
    12961 tattttgaag gcgtctactt cccttcattt ctttgatact aacaccataa aagttaccaa
    13021 cttcagtttg gattttatca attgggatga cgagcatttg gctaacatct tgtttgcggg
    13081 ctctaatggc ttctgcagca atatcaatag tgatatcctt gatttttttt actctggcaa
    13141 ttaaagtgat gtcgttgatg gctccctcaa gatctcgaac atttgaatca aattgcccag
    13201 ctaggtattc tagagtatca ctttggaaat tgtagcctaa atgttccgtt ttactttgta
    13261 aaatggcaat acgtgtttca aagtcagggg gtgtgatagt ttgtgtcaat ccccaactaa
    13321 aacgcgtgac aagcctctcc tcgagccctt ctagatgttt tggactacga tcactcgtta
    13381 ggacaatctg tttttgcttg tcatgaaggg cgttaaaggt attgaaaaat tcttcctgag
    13441 ttgcaacttt ttttccgctg agtgactgaa tatcatcgat taacaaaaga tcaagactac
    13501 gataggtctt tttaaacttt tccatttccc caagtcttag gtgatcaaga aagtcattaa
    13561 taaagctttc ggcagggata tatttaacac gcgcattagg aatatttttt agaatttcat
    13621 ttccaatagc gtttaataag tgagtcttac caaggcctgg tcctccatag ataaaaagag
    13681 ggttataggt cagagccaaa tcttcagaga cagctaaagc ggctgataca gcccaaacat
    13741 ttccatcccc ttgaataaag ttatcaaagg tatacttttc ttttaatccc gtatctgaat
    13801 aaggaataga tactaacttt ggactatagt tataaagagt taaatttgta gcttcttcaa
    13861 cttgtgagct agtcgtatct tgaggtttgg tgaaaatata gtggggagtt atttcagcgt
    13921 cataaatttc aaaaccagct actacaataa tatcttttag ttgtttttcc cagaccattt
    13981 ccatttcaga gcgaggtaga aatatagtgg caacattttc ctctaccttg atgagttcag
    14041 cttgaatagc atagaaatca tacatggatc gagtcagtct ttcttgtgca aattctaata
    14101 tacgattcca aaattgtttt tctttcaatc ctttctcctc ctttactatt taaaagttta
    14161 atactagaga tattttacca tagatagcaa gaattttcca caagctgtga aaaataatcc
    14221 acaatgttac caaactttat ccacaggttg gggataaaag aagaaattat tgatttatta
    14281 agctttttat cgaaaaacat agtggataac cttgtgagat aaaaaaataa aagaacagcc
    14341 ttatttcagg ctgttgataa ttctactata ttcttcttga tttgaaaaag aaataatgat
    14401 ttttccactg tcttttttag atagtttaat ttctacatct aatccgagta gttttcttaa
    14461 ctgtttttct tcattttgta tgaaatgatt agttttttgc tgtttctttt gttttttctc
    14521 tgtcagaaga gcttctaatt tccttacaga aatatcttct tctataatcc gttgaaagaa
    14581 atagtcttgt tgttccttat ttaacccaac tagggaacgc gcatgggctt gtgatagttt
    14641 gccattttct acttctgaaa gaatctgttc tggcaaggaa agtaaacgaa tggagttgct
    14701 gatatatgga cgagacttgc ccatcttatc tgcaatttca gcatgggtga atcctttctc
    14761 tacgagagat tcataggcgc gtgcttcttc tattgggttt aaattttctc tctgtaaatt
    14821 ttcaataatg gactggacca tcatctcttg gtctgaaatc tgtttaacaa cagctgggat
    14881 agaccgtaga ccagctaaaa gtgaagcccg atagcgtctc tctcctgcaa ggatttcata
    14941 accaataaca ggagattgac gaacaataat cggttgaatg accccatttt ctttgataga
    15001 ctgtgctagt tcatctagtt tttctctatc aaattctttt cggggttgat agggattttt
    15061 ttgtatatct gtgatagaaa tcatttcaaa tttttccatg attctacact aacacatctt
    15121 ttctcttatg taaagctttc tttacataga tgtcaatcaa gattctaaat cacctgaact
    15181 cttgttaagt ttgatagagg tagtttcttc tttcccgtta cgatagtagg ttatcttaat
    15241 ggtgtctccg atagaatggt tgtaaagagc actttgtaag tctgttgatg aagcaatctc
    15301 tttgtcatct acttttgtaa ttacatcgta tttttcaagg tgaccattgg caggcatatt
    15361 actttgtacc gaacgaacaa ctacaccaga tgtaacatta cttggaatat tgagtcttct
    15421 gatgtcgctt gtactcacat tagataaatt aaccatctgg attcccaaag ctggacgcgt
    15481 cacttttccg tttttttcta actgttcaat aatattgata gcatcatttg caggaattgc
    15541 gaaaccaaga ccttctacag atgttcctcc atttgtagca attttacttg aggtaattcc
    15601 gataacctgc ccttgaatat tgatcagtgg gccgccagag ttacctgggt taatagcagt
    15661 atcagtttgg atggcttttg tagaaatagc ttgtccatct tccgatctta aggatacatt
    15721 tctattgaga ctggatacga taccttgagt gacagtattt gcatattcag aacctaacgg
    15781 gctaccgatg gcaatagcag tttctcctac agttaactta ctagaatcac caaactcagc
    15841 tactgttgtc actttttctg aagagatttt gacgacagca atatcagaga aagtgtcagc
    15901 tccgacaatt tctccaggta ctttagtccc atctgacaat cgaatatcta ctttgctggc
    15961 gccatttata acgtgattgt tggtgacgat gtaagcttct ttatcattct ttttataaat
    16021 aactccagat ccttcactag agattcgctg agaatctgtg tcagtatcat cattgccaaa
    16081 tacgctattt tgtctgtttg ccgaataagt aataacagaa acaacagcat cttttacttt
    16141 gttaacagcc tgtgttgttg aattttcgtt cttataggca gtttgtgtaa tagtactatt
    16201 gttgttagag ttgtttacac tacttttttg agttagttga gttattgaaa aactacccaa
    16261 ggctccacta aaaaagctaa tgacgataac gactaataat tgaaaccatt ttttgtaaaa
    16321 tgtttttaga tgtttcatat ttgcctccat atgtttgaat tactgaaagt ataaactgac
    16381 tagcttaatt ataacttaaa cacaaaagtt ttacacaaac tgtggataac tcttttgaaa
    16441 ctgtgatttt cttaattgaa atctattttt tattttgtga ataagatgtg aaaaaataga
    16501 gaatatgtta gaatagagtc atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa
    16561 agtatttaaa agatggtatc gcagagtatt caaaacgaat ttctagattt gctaagtttg
    16621 aaatgattga gttatcagat gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa
    16681 agattttaga aatagaaggt cagagaattt tatcaaaaat tgctgaccgt gatttcgtta
    16741 ttgtgttagc cattgaaggg aaaactttct tctcagaaga atttagtaag cagttagaag
    16801 aaacttctat aaaaggattt tctactctta cttttattat tgggggaagt ttaggattgt
    16861 catcatctgt aaaaaataga gccaatcttt ctgtcagttt tggtcgccta accttacccc
    16921 atcagttaat gagactagtt cttgttgaac aaatctatcg cgcttttacg attcagcagg
    16981 gattccccta ccataaatag aaaattgact tttaattgaa tttttggtag aataattgta
    17041 ttagatctca tagctcagct ggatagagca ttcgccttct aagcgaacgg tcgcaggttc
    17101 gaatcctgct gggatcaata taatagcaaa gctgggaatt ttcccggctt ttttcttaaa
    17161 aaagtacact ttgggagaaa aaaatgacag ttgagagaat tttatctaaa acgaaattcc
    17221 attttgtata atggtttttg taagttagct tacaagaaaa aacattttag gagattttat
    17281 tatgaaaaac acagttaaat tggaacagtt tgtagctttg aaggaaaaag acttacaaaa
    17341 tattaaaggt ggggagatga ggatttcaag aatcatcctt gattttcttt tcctacgaaa
    17401 aaagtaatga aataaggaga aagagtaatg gatttacttg gatttgggac agttattgtt
    17461 cattttttaa ttattagtca cagttaccgt ttaatttgta aaggtcgaat aaatagaaaa
    17521 gaattatacg tttttggtgc ttatacatta ctaactgaaa tagtacttga attttccttt
    17581 tatcttctat atttagataa aatagggatt gaaagatttt tatttccttt gggcttatat
    17641 tcctattttc gatggatgaa acagtatgag agggatagag gactattcct aagtttacta
    17701 ctatctcttt tatatgagag cactcataac tttctgtccg taactttctc ctctataaca
    17761 ggagataatt ttgttttaca atatcatttc ccattctttt tcgttgtgac ggtgttaacc
    17821 tattttgtta cattaaaaat catttattat ttccatttgg aactagccta ttttgacaag
    17881 gactaccttt atcctttctt gaaaaaagta ttttttgctt tactattgct acatattgta
    17941 tctttcgttt cagatatggt aagtacgatt aaacatttga atagttttgg aagtattttg
    18001 tcatctattg tctttatctc tctccttttg accttctttg caatgaattc tcataaagtt
    18061 caaatggaga aagagattgc tttgaagcag aagaaatttg aacagaaaca tttacagaat
    18121 tacacagatg aaattgttgg tctgtataat gaaatccgtg gttttcgaca tgattatgct
    18181 ggaatgcttg tcagcatgca gatggcaatt gacagtggta atttacagga aattgacaga
    18241 atttacaatg aagttttagt caaagcaaat cataaattgc gttcagataa gtacacttac
    18301 tttgatttga acaacataga agactcagct ttacgaagtt tggttgctca gtcaattgtc
    18361 tatgctcgaa ataatggtgt agagtttaca ctggaagtaa aagatacgat taccaagctt
    18421 ccaattgaac tattggattt ggttcgtatc atgagcgttt tattgaataa tgctgtcgaa
    18481 ggatcggctg atagctataa aaagcagatg gaagtagcag ttattaagat ggaaactgaa
    18541 acagttatgg tgattcagaa ttcatgtaaa atgacgatga ctccttcagg agatctattt
    18601 gccttaggat tctccactaa gggaagaaat cgcggagtcg gattaaataa tgtgaaagaa
    18661 ctactagata agtacaacaa tattatttta gaaacagaga tggaaggcag tacatttaga
    18721 caaatcatta gatttaagag ggaatttgaa tgaaagtttt aattttagaa gatgttattg
    18781 aacatcaagt gagactagag agaatattgg atgaaatttc gaaagaatcg aatattccaa
    18841 tatcatacaa gacaacggga aaagtccgtg aatttgaaga atacattgaa aatgatgaag
    18901 taaatcagct ttatttccta gatatcgata ttcatggaat tgagaaaaag ggatttgaag
    18961 tggctcagct cattcgtcat tacaatcctt acgctattat cgtctttatc actagtcgat
    19021 cagagtttgc gactctaacc tataaatacc aggtatcagc cctagatttt gttgataagg
    19081 atatcaatga tgagatgttt aagaagagaa ttgagcaaaa tatcttctac acgaagagta
    19141 tgttacttga aaatgaagat gttgtagatt atttcgacta caattacaag ggaaatgatt
    19201 taaaaattcc ttaccatgat attttgtata ttgaaacaac aggggtatct cataaattgc
    19261 gcattattgg taagaatttt gcaaaagagt tttatggtac catgacagat attcaggaaa
    19321 aggacaaaca tactcagcga ttttattctc ctcacaagtc atttttggta aatataggca
    19381 atatcagaga aattgatcga aaaaacttag aaattgtttt ctatgaagac catcgttgtc
    19441 ctatttcaag attaaaaatt agaaaattaa aagatatttt agagaaaaaa tctcaaaagt
    19501 gattgacaat tagcaagaaa ttgatataat ggttatatct gctacagata gaaggtccgt
    19561 tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga atcccgtacg
    19621 gactatttta tccgccatag ctcagttggt agtagcgcat gactgttaat catgatgtcg
    19681 taggttcgag tcctactggc ggagtataga taaaagggaa cacagctgtg ttcctctttt
    19741 tgtatcaatt tgtatcacca agcattttca taaggaagtc tgttatttct tgagaacttt
    19801 ctttttttcc atgtgcaatc caagtttggc agacaccaaa aagtgcatga gttagataga
    19861 tgctactata ttctaattca gtggtattta gattcagttg cataaatcgc ttttgtaaat
    19921 ctgtactgag catgatatga agtttatttc gtaagaaatt ttggatttct ttagtcccat
    19981 tttcagaaag aagggcagcc agaagtggtt ctgactctag atattcaaaa acttctaaaa
    20041 tagcgtctct tttgtgatga gcatgttttt gaaaaatata ttcaaatgta tggaatagct
    20101 tgctttgata gtgctcaatc atatcatact tatccttata gtgagtatag aagctggaac
    20161 gactaattcc ggctttttct actaatttga cagtagaaat tttatcaaat ggctgttcca
    20221 tcagtaattg taccatagcg ttttcaatag ttcgctttgt ttttaagcgt ttgttacttt
    20281 cttgcatatt tcctccttgt aaacaaatta gactatatgt ctaaaaatag attttttatc
    20341 ttgtaattta gattttttaa tgtataatct attatatcaa aattttagac aatatgttta
    20401 aaaaaggaga aactatgttt aaagaatgga aagcaattta aaaaaaacca acctttatta
    20461 ttgtcatgat cgggatttct cttattccag ctctgtacaa tatcatattt ttgtcatcaa
    20521 tgtgggagcc atatgggcaa ttgtctgact tacctgtggc agttgtaaat aatgataaag
    20581 aggcttccta taatggtaat actatggcaa taggaaaaga catggtgtcc aatttaaaag
    20641 aaaataaaac cttggatttt cattttgtag atgaagagga aggaaagaag ggattggaag
    20701 atggcgatta ctatatggta gtgactttac caagtgattt atctgaaaaa acaactacat
    20761 tatccaatat tcaatcgaca gcagcttatc aatcattgac aagtgagcaa caaactgaga
    20821 taagtgattc tgtatctcaa aattcaactg atagtattca atcggctcag tcaattgtag
    20881 ctttagtaca agatttacag ggaattttag aaaacttaca aaatcaatct tctaatcttt
    20941 cgactttaaa aaatcaatct aatcaagtat cacctattac ttctacttct ttgataggat
    21001 tgtcaagtgg attaacagag atacaaggag atgttactag caaattagtt cctgccagtc
    21061 agtcgattgc atcaggtgta aacgcatata ctacaggtgt tgataaagtt tctcagggcg
    21121 caagtcaact aagtgaaaaa aatgccacct tgacaggtag tttggataaa ctagtttcag
    21181 gctcaaacac cttgacacaa aaatcttcta gattgacagc aggagttggt taattacaat
    21241 caggatctgg gcaattagca gacaaatcca gtcagttact ttcaggtgct tctccattag
    21301 agaatagagc taataaattg gcagatggat ctaggaaact agcagaaggt ggaacaaagt
    21361 taacttctgg attggaagat ttacagacag gacttgcttc tttaggacaa ggactaggta
    21421 atgctagtga tcaactcaaa tcagtatcaa cagaatctaa aaatgcagag attttgtcaa
    21481 atccactcaa tctttcaaaa acagacaatg atcaagttcc tgtaaatgga atcgcaatag
    21541 ctccttatat gatatcagtt gctctttttg ttgcagcaat atcaacaaat atgatatttg
    21601 cgaaattgcc ttcaggacgt catccagaga gccgttgggc ttggttgaaa tctcgagctg
    21661 aaataaatgg tattatagct gttttggcag gaattttggt atatggagga gttcagctta
    21721 ttggtttaac tgctaatcat gagatgagaa tatttattct catcatccta acaagtttag
    21781 tattcatgtc tatggtgacc actttaacaa cgtggaatag ccgtatagga gctttcttct
    21841 cacttatttt gcttttacta cagttagcat caagtgcagg tacttatcca cttgctttga
    21901 caaatgattt ctttagatct attaatccct ggttaccaat gagctattca gtttcgggat
    21961 tacgacaaac aatctccatc aacaagtcat tttcctagct gtcatactag ctctatttac
    22021 tggtttaggt atgctagcct atcaacataa gaaaatggaa gaagattaaa aaaatcgacc
    22081 gattaactgg tcgatttttt atgccttaga tgactttcgt ctgtgattat agattccaaa
    22141 tagtaagaga gaagtaaagg aacagattgc tccagtaata aaaccattgg gaatgaagga
    22201 aagtgtaata gttcctttcc ccttgggaat gtcaactttc ataaatccag tttgagcttg
    22261 tttaatttct attttcttac catcttggta ggcagaccaa cctttgtcat aaggaatggt
    22321 gaagaaaata gatgtatctt gttggacatc atatgtagca aaaaccttgt ttttagaagt
    22381 tgatactgtg acaggttgtt ctttaatttt ttgaattgcc tcggtgaaag ttttggtatc
    22441 taaacgatag aaggtaggag attcaaatga tacttgtgaa tttccaggga aactaacatt
    22501 gatattgaaa gtttttttct ctttagtata tcctagatta aagaaggaga agacattatc
    22561 agttgtaaaa gtcttttttt caccatttac aaggatgtca accttctttt gtttatcgtt
    22621 agaaaagtga aggtttatga aagagagata aacttggctg ttttctggaa cttcaatttg
    22681 atactggatt gctgcatctt catttgaaga acttgtgaca ctaatcaaat cattagtatt
    22741 ttctattttt tctgtttttt cataaggtat tggagaaaaa taatcaaaat tgacgttagc
    22801 aagttgattt aaaaatgagg cctgattatc caaggtatgt tcattgaact tgacatcatt
    22861 gtaaacagat tgactagcaa ctgcaatcgg aagagagtat tgattttcat atagggtaag
    22921 attatctttt tgatagatat ctttaaagcc atacttatca ataggactgt ctgagatatt
    22981 gtactggata ccaaataaac tatcagccaa aatactatta tttgcatatc ggagattgag
    23041 attagtccca gaggatttaa aaccaagttt atctaaagta gagcttgatg aacgatttcg
    23101 aacagatgaa aattgagaga ttccattgta gttgaatttc atactgtcat ttcctgtctg
    23161 agtttgtagt ttttcagtac gagtaaattg atttccaata tatgttgaga aagattccat
    23221 agctgggata tctcgactat aagcacttcg agaagcaaat ccccattcct tagcaattcc
    23281 gtccatttga gatgaagcat ttaaactcat ttcaaccagt ataaataaag agattagaat
    23341 ggcaaataga ttcacagata taaacttttt gataactgca aggagtaaaa gagaatagac
    23401 aaccaaaaat tcaagagtaa gcagaatatt caaatctgtt aaaaaagaat aatgcgattt
    23461 tagatagatg gtagctaaaa atcctgctac tacaagaaaa agcgaaacta aaaaattcca
    23521 gactttaagt tctttcagac gctttaagac ttctgctgct gtgtaaatta acaaggtaga
    23581 gaaaatccaa gcatagcgat gtaaaaacat gtttggagta tgcatgcctt gccaaaataa
    23641 gtcaagagct tctatgtaaa agcttgcaat tagaaatgca aagaatatta catatatgag
    23701 tttcacgtga aacttaatag atttcagcgt aaaaaataaa atggtcaaaa taaagggaag
    23761 tagtccaaca aaaatcattg ggatggcccc atactttgtt gtgtcaaagg aaccaatgaa
    23821 ttgcttagca aagagatcaa gataccagct actttcagtt tgaaactttg taacttcagt
    23881 caatttttcc ccatgtgtct gtaaatcaaa tagagtggga agagtcataa tcaaactagc
    23941 cataccagct aaaaaggaga taactatgaa atcaagaaca gatgattttc gagtcttaaa
    24001 gtcccacgaa atttgacaga gataccagaa aataagaaac aatactgtca tatatccaaa
    24061 ataataattt tgaataaata agattgacag acttgtaaag tacaatagga gtttcttttc
    24121 agttatcagt agatgtaaac cagttataat taaaggaatc aagataaaaa catctagcca
    24181 ggtttttatc tctaattgac tgacagtgaa actcatcaga gcataggaag tagataaggc
    24241 tagttttaaa gtctgaggga tagattgaaa caatttattc aaactaaaaa aggttgacag
    24301 accaatcaat ccaaatttta agagagtggt cagatagaca gcatctggca tattcgttag
    24361 atcaaaaaag taaactagag gcgcgagaaa actacccaag taataactag atagggcata
    24421 gaagtttagc cctagaccac ttgtaaaggt gtaaaacaga ctactatttc catgtaggat
    24481 atttcgtaag gctacatcaa aaataacgta ttgatgaaag ccatctccta atagaggaga
    24541 gttgtcgcta ttccagtaga taccttgaga tagatatact ccagacataa tcactacagg
    24601 aatgatgaaa gaaataaaat aggttcgata tgtttttaaa aatgatttca tgttacctcg
    24661 tagaatgata gaaaactcag ttggttaacc caactgagtt ttgaagtttt atttagtctt
    24721 tccaaagttc tttaactttt gcttgtactt ctgcattttc taggaattca tcgtaggttt
    24781 catcgatacg gtcaatgacg ccatttttag ataagacaat gatatggtta gccaaagttt
    24841 gaataaactc gtggtcatgg ctggcaaaga tgattgattc tttaaagttt ttcaatccat
    24901 cattcaagct tgagatagat tccaagtcca agtgatttgt tggatcatca agtacaagga
    24961 catttgattt taagagcatg agttttgaaa gcatgacacg aactttttct ccccctgaca
    25021 agacatttac aggtttgtta acttcatctc cagagaagag catacggccg aggaagccac
    25081 gtaggaaagt attgtcatct tcttctttac ttgcgaattg acgcaaccag tcaagaattg
    25141 attctcctcc tgcaaaatca gctgagttat cttttggtag gtaagattga ctagttgtaa
    25201 ctccccactt gacagttcct tcatagtcaa tatctcccat gattgcacga attaatgcag
    25261 tcgtttgaat atcattttgt ccaataagtg ctgtcttatc atctggacgc aagatgaaac
    25321 taatattatc caagatagtt tcaccatcaa tctttacagt tagattttct actgtcaaga
    25381 gatcattacc aatctcacgt tccgctttaa agttgataaa tggatattta cgactagatg
    25441 gtacaatctc ttctagctca atcttatcaa gcattttctt acgtgatgtt gcctgccttg
    25501 acttagaagc attggcagag aaacgagcaa cgaattcttg caattgttta attttttctt
    25561 ctgctttagc attacggtct gctagcaatt tagcagcaag ctcagaagat tccttccaga
    25621 agtcgtagtt tccgacatag agtttgattt ttccaaagtc aaggtcggcc atgtgagtac
    25681 aaactttgtt taagaagtga cggtcgtggg atactacgat aactgtgtta tcaaagtcaa
    25741 tcaagaagtc ttctaaccaa gtaatcgatt ggatatccaa accgttagta ggctcgtcca
    25801 agagaagaac atctggttta ccaaaaagtg ctttggcgag gagaaccttt actttttcac
    25861 cgttggccaa ttcgctcatg ttttggtagt gtaattcttc tggaatgttt aggttttgaa
    25921 gtagttgaga ggcttcactc tctgcttccc aacctccaag ttcggcaaac tctccttcga
    25981 gttcggcagc acgaaccccg tcctcgtctg agaaatcttc cttcatgtag atagcatctt
    26041 tctctttcat gatgctataa agtttttcat ttcccatgat aacgacatca atggcacgtt
    26101 catcttcgta gtcaaagtga ttttgacgaa gaacagagag acgttcatct ggaccaagag
    26161 agatgtgacc agtagtaggt tcgatatctc cagctaaaat ttttaaaaag gttgattttc
    26221 cggcaccatt agcaccgatt aatccgtaag tatttccttc tgtaaatttg atattgacat
    26281 catcaaaaag tttgcgatca ctaaaacgta gtgaaacatc agatactgta agcaatattt
    26341 ttctcctata tgtgtaatat atttattcta ctagaaaata cagaaatatt caaattttta
    26401 tttgtcaatt ttgtgtaaat tatatttaca gtatccttta cacaaatctg taaaaagcaa
    26461 ggctgattta ttttgataaa ttacggttat ttcattaaaa aaatgctata attgaaagga
    26521 ctatatcgaa ggagaacaaa atgactaaac ccattatttt aacaggagac cgtccaacag
    26581 gaaaattgca tattggacat tatgttggaa gtctcaaaaa tcgagtatta ttacaggaag
    26641 aggataagta tgatatgttt gtgttcttgg ctgaccaaca agccttgaca gatcatgcca
    26701 aagatcctca aaccattgta gagtctatcg gaaatgtggc tttggattat cttgcagttg
    26761 gattggatcc aaataagtca actattttta ttcaaagcca gattccagag ttggctgagt
    26821 tgtctatgta ttatatgaat ctagtttcgt tagcacgttt ggagcgaaat ccaacagtca
    26881 agacagagat ttctcagaaa ggatttggag aaagcattcc gacaggattc ttggtctatc
    26941 caatcgctca agcagctgat atcacagctt tcaaggctaa ttatgttcct gttgggacag
    27001 atcagaaacc aatgattgag caaactcgtg aaattgttcg ttcttttaac aatgcatata
    27061 actgtgatgt cttggtagag ccggaaggta tttatccaga aaatgagaga gcagggcgtt
    27121 tgcctggttt agatggaaat gctaaaatgt ctaaatcact aaataatggt atttatttag
    27181 ctgatgatgc ggatactttg cgtaaaaaag taatgagtat gtatacagat ccagatcata
    27241 tccgcgttga ggatccaggt aagattgagg gaaatatggt tttccattat ctagatgttt
    27301 ttggtcgtcc agaagatgct caagaaattg ctgatatgaa agaacgttat caacgaggtg
    27361 gtcttggtga tgtgaagacc aagcgttatc tacttgaaat attagaacgt gaactgggtc
    27421 ctattcgtga gcgccgtatt gaatttgcta aggatatggg agaagtttat aatatgattc
    27481 aaaaaggtag tgaaagagcg cgtgaagttg cgggtcaaac cctatctgag gtaaaagggg
    27541 caatgggact tcattacttt aactaagttt attttacaag aaactatctt ttctatctcg
    27601 aagaaaagat agttttttat ttacccctgt aacatttgac aaatttttat agaatggtat
    27661 gatagataca atataaaaag agtcaagctc aaaaagaaag aaaagaggaa acttcgaatg
    27721 tctaattggg acactaaatt tttgaaaaaa ggttttacct ttgatgatgt attgcttatt
    27781 ccagctgaaa gtcatgtgtt gcctaacgat gcagatttaa caactaaatt ggcagataat
    27841 ttgactttaa atatcccaat tattaccgct gccatggaca cagttacaga gagtcaaatg
    27901 gccattgcta ttgctcgtgc aggcggtctc ggagttatcc ataaaaacat gtcaattgct
    27961 caacaagcag acgaggttcg taaggtaaaa cgttctgaaa atggagttat tattgatccg
    28021 ttcttcttga cgcctgaaca tacaattgct gaagcagatg agcttatggg tcgttaccgc
    28081 atcagtggtg ttccagttgt tgaaacactt gaaaatcgta aattggttgg tattttgaca
    28141 aaccgagatc ttcgttttat ttcagattat aatcaaccaa tttcaaacca tatgactagt
    28201 gaaaatcttg ttactgctcc tgtgggtacg gatcttgcaa cggctgagag tattcttcaa
    28261 gagcatcgta ttgaaaaact tccgttggtc gatgaagaag gcagtctttc tggtttgatc
    28321 actatcaaag atattgaaaa agttattgag tttccaaatg cggctaaaga tgagtttggt
    28381 cgtcttctag ttgcaggtgc agtaggtgtt acttcagata catttgaacg tgcagaggct
    28441 ctttttgagg caggagcgga tgcgattgtt attgatactg cacatggtca ttctgcaggt
    28501 gtcttgcgta aaattgccga gattcgtgct catttcccag atcggacttt gattgctgga
    28561 aatattgcta ctgctgaagg tgcacgtgcc ctttatgaag cgggtgtaga cgttgttaag
    28621 gttggtattg gaccaggttc tatctgtact actcgtgtga ttgctggtgt tggtgttccg
    28681 caagtaacag ctatctacga tgctgcagct gttgcgcgcg aatatggtaa aacgattatt
    28741 gctgacggtg ggatcaagta ttctggagat attgtaaaag cacttgctgc aggtggaaat
    28801 gctgttatgc ttggatctat gtttgctgga actgatgaag ctccaggcga aactgaaatc
    28861 ttccaaggac gtaaattcaa gacttaccgt ggtatgggat caattgctgc tatgaagaaa
    28921 ggttcaagcg accgttattt ccaaggttct gtcaatgaag caaacaagct tgttccagaa
    28981 ggaattgaag gtcgtgttgc ttataaagga gcggcagctg atattgtttt ccaaatgatt
    29041 ggtggtattc gctctggtat gggttactgt ggtgcagcta accttaaaga actacacgat
    29101 aatgctcaat ttattgaaat gtctggtgct ggtttgaaag aaagccatcc tcatgatgtg
    29161 caaattacta atgaggcacc aaattattct atgtaaaaaa caatgaaaag aactccagtg
    29221 aaaacaggag ttcttttaca atgttgtcaa tttccattta cagaagcttt accatcctga
    29281 atagtgaaga tacttagatt ttctggcaga ttttgaagat ggtctaagct tgttgttgtg
    29341 ataaaggttt ggattgattg agaaatcgtt tctaataatt ttaactgtct agtgttgtca
    29401 agttcactca tcacatcgtc aagcagtaat atcggagatt ctgtggtaat gctttccatt
    29461 aattcgattt ctgctaattt tatcgagagg acgagactac gatgttgacc ttggcttccg
    29521 aaactagcat ccatcccatt tatataaaaa gaaatgtcat ctcgatgagg accgacacca
    29581 gtattctttt taaataaatc tctggatcta cttttttcta aagcaatttt gaaagattcg
    29641 gataagtttt gtttgtcagt tatattgaca gaagattgat aggatattga caactcttcg
    29701 atctgattag agagttcaaa atgtttctta cgcccaaatg attctagttt ttttatgaaa
    29761 tctaagcggt gattcattac acgacatcca taatcaacta gctgatcatc taacacagaa
    29821 aggaatgttt catctatttt ttgatctgat tttaggtaag tgtttctttg ctttaggatg
    29881 tggttataat tggttaagtc agataagtag attggcttaa tttgcccaag ttccatatca
    29941 atgaattttc gtcgaatcga aggtgctcct ttaattagtt gtaaatcttc aggagcaaat
    30001 aagacaacat tcatgtgtcc tacataatct gaaaggcgtg cctgttttaa gtgattaact
    30061 tttgttacac ggcctttttg tgttagttcg atttctaggg gaatggatcc agtttttttc
    30121 tgaacgagac ctgaaagatg aagttgttcc tcatcaaaat gaatgagatt tttatctgtt
    30181 cgagttcgat gactacgcgt taaggctaaa aaatagatag cctctaacat gtttgttttt
    30241 ccttgtgcat tacgtcccaa aaagacattc aatttaggat taaagtctat tttcgtttct
    30301 ttgtaattac gaaaagtctt gagagataga tgttgtagcc acatgattat ctaccaggga
    30361 atcgtggagc ttgttggctt ttaggtgatg aagcaggttt cgatttgtct tttttaactc
    30421 ccttattcat ctttttgaca agtttagcga tccgttcttt ttcaacttta tcagcttggt
    30481 attcatcttg ttcttcagaa gtaggttgtg tcaacaagat gtcaatgttc atgtcaggga
    30541 tgtcaacttt atcgccaata cgaagttttt ttccacgacg actctctaat tccctattaa
    30601 agtaaacaga atgttcagag agaaatgatt taatagctcc tccgctatgt gtaattccaa
    30661 gttctttgag tagtgcttgg agggtaataa attcttcaaa taatttgtat tccataattc
    30721 acctcaatct ttggtattat accatatttt cctaaaaata gtgagagaga cagcgagaaa
    30781 tgtaagcgat ttttatttca aaagtgttac agggaacaag aaaatttcag gttttcgtga
    30841 tataatagaa gtctgtatat aaggaggtaa atcatggagt tagtgcatgg aatttcaaca
    30901 cattttatcc aatcaaaaaa gtttaaaaca aacaaaatta ccgtgcgttt taccgctcca
    30961 ttatcccttg atacgattgc aggtcacatg ttgagtgcaa gtatgctaga gactgctaat
    31021 cagatgtacc ccacttctca agatttgagg agacacttgg ccagtctata cggtacagat
    31081 atgtcaacca attgtttcag aagagggcaa agccacatta tagaattgac atttacctat
    31141 gttcgtgatg agtttttaag taggaaaaac gtgctaacct ctcagatttt ggaacttgta
    31201 aaagaaactc ttttttcacc cgtagtagtt gataatgggt ttgatccggc cttatttgaa
    31261 attgagaaaa aacaattgct agcaagttta gcagctgata tggatgattc tttttatttt
    31321 gcacataaag aattggataa attgtttttt catgatgaac gtcttcaatt ggaatatagt
    31381 gatttacgaa atcgtatttt agctgaaact ccacaaagtt cttattcttg tttccaagaa
    31441 tttttagcca atgatcgaat agatttcttt ttcctaggtg attttaatga ggttgaaatt
    31501 caaaatgtat tagaatcatt tggctttaaa ggtcgaaaag gagatgtgaa ggttcagtat
    31561 tgtcaacctt attctaatat ccttcaggaa ggtatggttc ggaaaaatgt gggacaatct
    31621 attttggaat taggttatca ttaccgttct aaatatggtg atgagcaaca tttacccatg
    31681 attgtaatga atggtttact tggtggattt gctcactcta agctctttac aaatgtccgt
    31741 gaaaatgctg gattagctta taccatttca agtgagcttg atttatttag tggattcttg
    31801 aggatgtatg ctggtatcaa tcgagaaaat cgtaaccagg ctcgtaaaat gatgaataat
    31861 caactgcttg atttaaaaaa aggttatttt acagagtttg agttaaatca gaccaaggaa
    31921 atgattcgtt ggtcgttgtt actttctcaa gataatcaat cttcattgat tgaacgtgct
    31981 tatcaaaatg ccttatttgg aaaatcttca gcagacttta aaagttggat tgcaaagctt
    32041 gaacaaattg acaaagatgc tatttgtaga gtagctaata atgtgaaact acaagcgatt
    32101 tactttatgg aaggaataga atgacaaagg ttgtttttga agaaaaatac tatccagctg
    32161 taaaagaaat ggtttatcga actcgtttgg caaatggatt gacagtagct cttttgccta
    32221 aaaaggaatt taaagaggtt tacgggagtg taactgtaca gtttggttcg gtagatacgc
    32281 ttgtcacaga agttgatgga gatgtaaaac aatatcctgc aggaattgct cattttcttg
    32341 aacataaatt atttgaaaga gaagattcta gcgatttgat gtcggctttt acgagtctag
    32401 gtgcagatag taatgccttt acaagcttta caaaaacaaa ctatcttttt tcagcaacgg
    32461 attatttttt agaaaattta gatttacttg atgaattggt aacatcagca cactttactg
    32521 aagcttccat tctgacagag caggatatta ttcagcaaga acgagaaatg taccaagatg
    32581 atccagattc gtgtttattc ttttcaactt tagcgaattt gtatcctggt acacctttag
    32641 caactgatat agttggaagt gaggagtccg tttcccaaat caatctaact aatttgcaag
    32701 aaaattttac aaagttttac aaacctgtaa acatgtctct gtttttagtt ggtaattttg
    32761 atgtggagcg agtacaggac tattttgaaa gcaaagaact gaaagattca gattttcagg
    32821 aagtagcaag agaaaagttg tttttacagc ctgtaaagct aacagatagt atgagaatgg
    32881 aagtatcttc tcccaaacta gcgattggag ttagaggtaa gcgagaagtt tctgaagcgg
    32941 attgctatcg acatcatatt ttattaaaat tattgtttgc aatgatgttt ggttggactt
    33001 cggatcgttt tcaaaaatgt tatgaatcag gtaaaattga tgcatcctta tctctggaag
    33061 ttgaagtaac aagtcgcttt cattttgtca tgttgacaat ggatacgaaa gagccagttg
    33121 ctttgtctca tcaatttagg aaggctattc gtaattttac aaaggattta gatattacag
    33181 aggaacattt agatattatc aaaagagaga tgtttggcga atttttcagt agcatgaact
    33241 ctcttgaatt tattgcaacg caatatgatg cttttgaaaa tggtgagaca atttttgatt
    33301 tgccgaaaat tttacaggaa attactttag aggatgtcct tgatgctgga catcatttaa
    33361 tatatgatgg tgacatagtt gattttacaa tatttccatc gtagtaacct atcataatag
    33421 acactagaaa gaagggatga caagtatgag aaaaaaaaca attggagagg ttttacgatt
    33481 agctagaatc aatcagggat tgagtttaga tgaattgcag aaaaagacag aaatccagtt
    33541 agatatgttg gaagcaatgg aagcagacga tttcgatcaa cttccaagtc ctttttacac
    33601 gcgttctttc ttgaaaaaat atgcatgggc tgttgagtta gatgaccaaa ttgttttgga
    33661 tgcttatgat tctgggagta tgattactta tgaggaagta gatgttgatg aagatgagtt
    33721 gacaggtcgt agacgttcaa gtaagaaaaa gaagaaaaaa acatcatttt tacctttatt
    33781 ttattttatc ctttttgctt tatcgatttt aatttttgtg acttattatg tttggaacta
    33841 tattcaaact caaccagagg agccttctct ttctaattac agtgtggttc aatcaacaag
    33901 ttcaactagc tctgttcccc actcctcaag tagtagttct tctagtatag aatcagctat
    33961 aagtgtatca ggcgaaggaa atcatgtaga aatcgcttat aagacaagta aggaaacagt
    34021 taaattgcaa ttggcagttt cagatgttac aagttgggtc agtgtttcag aaagcgaact
    34081 tgagggcggt gtaaccttat cgccaaagaa gaaaagtgca gaagcaacag ttgcaactaa
    34141 aagtcctgta acaattacgt taggtgttgt aaaaggtgtt gatttgacag tagataatca
    34201 gactgttgat ttatcgaaat taacagctca gactggacaa atcactgtaa cctttactaa
    34261 aaattaagga aaaacgaatg aaaaaagaac aaattcccaa tctcttaaca ataggtcgaa
    34321 ttctctttat acctattttt atctttattt taacgatagg aaattcgata gagagtcata
    34381 tagttgcagc tattatcttt gctgttgcca gtattaccga ctatttagat ggatatttag
    34441 ctcgtaaatg gaatgtggtc agtaattttg gtaaatttgc agatcctatg gcggataagt
    34501 tactagttat gtcggctttt attatgttga ttgagttagg tatggctccg gcttggattg
    34561 ttgcagtgat tatctgtcgt gagttagctg tgacaggttt aaggctttta ttggttgaaa
    34621 ctggtggaac aattttagca gcagcaatgc ctggaaaaat taaaactttt agtcagatgt
    34681 ttgctattat tttcttgcta ttacattgga ctttgcttgg tcaagttcta ctttatgtag
    34741 ccttattttt cactatctac tctggctatg actatttcaa gggtagtgcc tatgtattta
    34801 aagggacatt tggttcgaaa tgaaatcaat aattgatgta aaaaatcttt cttttcgcta
    34861 taaagaaaat cagaactact acgatgtgaa ggatattacg tttcacgtga aacatggaga
    34921 atggctttcg attgtagggc ataatggtag tggtaaatca acgacggttc gattaattga
    34981 tggcttactg gaagcagaat ccggagagat tgtaattgat ggccaacgtt tgactgagga
    35041 aaatgtttgg aatatacgtc gtcaaatcgg tatggttttt caaaatccag acaatcaatt
    35101 tgttggagcg actgttgaag atgatgttgc ttttggtttg gaaaatcagg gactttctcg
    35161 tcaagaaatg aaaaagagag tagaagaagc tctggcttta gttggcatgt tggactttaa
    35221 aaagagagag ccagcgcgtc tatcaggtgg ccaaaagcaa cgtgtggcca ttgcaggtgt
    35281 tgtagcccta agaccagcta ttttaatctt agatgaagca acgagtatgt tggatcctga
    35341 ggggcgtaga gaacttattg ggacagtaaa aggaattcga aaagactatg atatgacggt
    35401 catttctatt acccatgatt tggaagaagt cgccatgagt gatcgcgtat tggtcatgaa
    35461 aaaaggggaa attgaatcaa ctagtagtcc aagggagctt ttctctcgaa atgatttaga
    35521 tcaaattgga ttagacgatc cttttgctaa tcaattaaaa aaatctttga gccagaatgg
    35581 ctatgattta cctgaaaatt atttgacaga aagtgagcta gaggataagc tatgggaatt
    35641 gctctagaaa atgtgaattt tacatatcaa gaaggtactc ccttagcttc agcagctttg
    35701 tcggatgttt ctttgacgat tgaagatggc tcttatacag ctttaattgg gcacacaggt
    35761 agtggtaaat caactatttt acaactctta aatggtttat tggtgccaag tcaagggagt
    35821 gtgaggattt ttgatacctt aatcacctcg acttctaaaa ataaagatat tcgtcaaatt
    35881 agaaaacagg ttggcttggt atttcagttt gctgaaaatc agatttttga agaaacggtt
    35941 ttgaaggacg ttgcttttgg accgcaaaat tttggagttt ctgaagaaga tgctgtgaag
    36001 actgcgcgtg agaaactggc tctggttgga attgatgaat cactttttga tcgtagtccg
    36061 tttgagctgt cagggggaca aatgagacgt gttgccattg caggcatact tgccatggag
    36121 ccagctatat tagtcttaga tgagccaaca gctggtctag atcctctagg gagaaaagag
    36181 ttgatgaccc tgttcaaaaa actccaccag tcagggatga ccatcgtctt ggtaacgcat
    36241 ttgatggatg atgttgctga atatgcaaat caagtctatg taatggaaaa gggacgttta
    36301 gtaaaggggg gcaaaccaag tgatgtcttt caagacgttg tttttatgga agaagttcag
    36361 ttgggagtac ctaaaattac ggccttttgt aaacgattgg ctgatagagg cgtgtcattt
    36421 aaacgattac cgattaagat agaggagttc aaggagtcgc taaatggata gtatgatttt
    36481 ggggcgttat atcccagggg attcgattgt tcaccgattg gatccacgta gcaaattgct
    36541 tgctatgatg ctactgattt tgattgtgtt ttgggctaat aaccccttga cgaatctgat
    36601 tctttttata gcgacaggga tatttattgc cttgtcagga gtatctcttt cattttttat
    36661 tcagggcttg aagtctatgt ttttcttgat tgccttcaca actatttttc aactattttt
    36721 catttctaat gggaatgttt tatttgagtt ttcgtttgtg agaatcacgg attatgcttt
    36781 gcaacaagct gggattattt tttgtcgctt tgtattgatt attttctttt caactttgtt
    36841 aaccttaaca accatgcctt taagtttggc atcagctgtc gaagctttat tagcaccttt
    36901 aaagcgtgtg aaagttccag ttcatgaaat tggattgatg ctgtctatga gtttgcgttt
    36961 tgtcccaacc ttgatggatg atacgacgcg gattatgaat gcacagaaag ctcgtggagt
    37021 ggattttgga gaaggaagta tcgttcaaaa agtaaaggcg atgattccca ttttgattcc
    37081 tctttttgcg acaagtttaa aacgtgcaga ttccttggct atcgctatgg aagcgcgtgg
    37141 ctatcagggt ggaaaaggca gaagtcaata ccgacaattg aaatggactc taaaggatac
    37201 gctgaccatt cttgttattc tcgtacttgg ttgttgttta tttttcttaa aatcttagta
    37261 gctttcagga attgataaaa agttactgta acagtttttg atataaaggt agggatatga
    37321 accgttttaa aaaatcaaaa tatgtcatta ttgtttttgt cactgttctg cttgtgtcag
    37381 ctctcttagc gacgacttat tcaagtacaa ttgtgacaaa attaggagat ggaatctcat
    37441 tggttgatag agttgtacaa aaaccttttc agtggtttga ttctgtcaaa tcagatttgg
    37501 ctcatttgac acgaacatat aatgaaaatg aaagtttgaa gaaacagctt taccaattag
    37561 aagttaaatc aaatgaggtg gaaagtttaa agacagaaaa tgaacaactg cgccaattgc
    37621 ttgatatgaa gtctaaattg caagccacaa agactttagc agcagatgtt attatgcgtt
    37681 ctccggtatc ttggaagcag gagttgacct tagatgcagg tagatcaaaa ggtgcttctg
    37741 agaacatgtt agctattgca aatggtggct tgattgggag tgtttcaaaa gtagaggaga
    37801 actctactat agtcaacctt ctgacaaata cggaaaatgc tgataagatt tctgttaaaa
    37861 ttcaacatgg ctctactaca atttatggaa ttattattgg ctatgacaag gaaaatgacg
    37921 ttcttaaaat tagccaatta aatagtaata gcgatattag tgcgggagat aaggtgacta
    37981 ctggtggatt aggaaacttt aacgttgctg atattcctgt tggtgaagtg gttgccacaa
    38041 cgcatagtac agactatttg acacgagaag taactgttaa attgagtgca gatactcata
    38101 atgtagatgt gatagaatta gtggggaatt cataatgaga cagttgaagc gagttggagt
    38161 atttttattg cttcctttct ttgttctaat tgacgcccat attagccagc ttctgggctc
    38221 atttttcccc catgtacatt tggctagtca ttttcttttt ctatttctct tatttgagac
    38281 gatagaagta tcagagtatc tctacctagt ctattgtttt gttataggct tggtttatga
    38341 tgtttacttt ttccatctaa tagggattac aactctctta tttatcttat tgggagcctt
    38401 ccttcataaa ttgaatagtg ttattttgtt gaatcgttgg acaagaatgc tagctatgat
    38461 tgtgctgaca ttcctgtttg aaatgggtag ttatcttttg gcttttatgg tagggttgac
    38521 agtagatagc atgtcgattt ttatagtcta tagcttggta ccgacgatga ttttaaattt
    38581 tttatggatt actgtttttc aatttatttt tgaaaaatat tatctataag aacgacatat
    38641 aaatgtaaca aaggcgtaat atttattagg cctttttttg gtatactagt attgtcttta
    38701 aaagaaggag tatctacgta atatgaagaa aaaaatctta gcgtcacttt tattaagtac
    38761 agtaatggtt tctcaagtag ctgttttaac aactgcgcat gcagaaacga ctgatgacaa
    38821 aattgctgct caagataata aaattagtaa cttaacagca caacaacaag aagcccaaaa
    38881 acaagttgac caaattcagg agcaagtatc agctattcaa gctgagcagt ctaacttgca
    38941 agctgaaaat gatagattac aagcagaatc taagaaactc gagggtgaga ttacagaact
    39001 ttctaaaaac attgtttctc gtaaccaatc gttggaaaaa caagctcgta gtgctcaaac
    39061 aaatggagcc gtaactagct atatcaatac cattgtaaac tcaaaatcaa ttacagaagc
    39121 tatttcacgt gttgctgcaa tgagtgaaat cgtatctgca aacaacaaaa tgttagaaca
    39181 acaaaaggca gataaaaaag ctatttctga aaaacaagta gcaaataatg atgctatcaa
    39241 tactgtaatt gctaatcaac aaaaattggc tgatgatgct caagcattga ctacgaaaca
    39301 ggcagaacta aaagctgctg aattaagtct tgctgctgag aaagcgacag ctgaagggga
    39361 aaaagcaagt ctattagagc aaaaagcagc agctgaggca gaggctcgtg cagctgcggt
    39421 agcagaagca gcttataaag aaaaacgagc tagccaacaa caatcagtac ttgcttcagc
    39481 aaacactaac ttaacagctc aagtgcaagc agtatctgaa tctgcagcag cacctgtccg
    39541 tgcaaaagtt cgtccaacat acagtacaaa cgcttcaagt tatccaattg gagaatgtac
    39601 atggggagta aaaacattgg caccttgggc tggagactac tggggtaatg gagcacagtg
    39661 ggctacaagt gcagcagcag caggtttccg tacaggttca acacctcaag ttggagcaat
    39721 tgcatgttgg aatgatggtg gatatggtca cgtagcggtt gttacagctg ttgaatcaac
    39781 aacacgtatc caagtatcag aatcaaatta tgcaggtaat cgtacaattg gaaatcaccg
    39841 tggatggttc aatccaacaa caacttctga aggttttgtt acatatattt atgcagatta
    39901 atttacagag ggactcgaat agagccctct tttcaggttt taccgtgaca atccctatta
    39961 aaaattatat caaaatagct tgaaaatatt ggaaaagtat ggtagaatga aaattgtcgt
    40021 gtgaacgata atactcattc ttgatgaatt gtgaagcagt tgcccttggg tcgttttgcg
    40081 agttgaagtc aagaagagga aaaaaacaaa aaggagaaat actcatggca gtaatttcaa
    40141 tgaaacaact tcttgaggct ggtgtacact ttggtcacca aactcgtcgc tggaatccta
    40201 agatggctaa gtacatcttt actgaacgta acggaatcca cgttatcgac ttgcaacaaa
    40261 ctgtaaaata cgctgaccaa gcatacgact tcatgcgtga tgcagcagct aacgatgcag
    40321 ttgtattgtt cgttggtact aagaaacaag cagctgatgc agttgctgaa gaagcagtac
    40381 gttcaggtca atacttcatc aaccaccgtt ggttgggtgg aactcttaca aactggggaa
    40441 caatccaaaa acgtatcgct cgtttgaaag aaattaaacg tatggaagaa gatggaactt
    40501 tcgaagttct tcctaagaaa gaagttgcac ttcttaacaa acaacgtgcg cgtcttgaaa
    40561 aattcttggg tggtatcgaa gatatgcctc gtatcccaga tgtgatgtac gtagttgacc
    40621 cacataaaga gcaaatcgct gttaaagaag ctaaaaaatt gggaatccca gttgtagcga
    40681 tggttgacac caatactgat ccagatgata tcgatgtaat catcccagct aacgatgacg
    40741 ctatccgtgc tgttaaattg atcacagcta aattggctga cgctattatc gaaggacgtc
    40801 aaggtgagga tgcagtagca gttgaagcag aatttgcagc ttcagaaact caagcagatt
    40861 caattgaaga aatcgttgaa gttgtagaag gtgacaacgc ttaatttata caaatagtaa
    40921 ttacctagga gggcggggct tagcccggct ctcctatttt caaaaaatat aggagaatta
    40981 aaatggcaga aattacagct aaacttgtaa aagagttgcg tgaaaaatct ggtgccggtg
    41041 ttatggacgc taaaaaagcg cttgtagaaa cagacggtga catcgaaaaa gcgattgaat
    41101 tgcttcgtga aaaaggtatg gctaaggcag ctaagaaagc tgaccgtgtt gctgcagaag
    41161 gtttgactgg tgtttatgtt aacggtaatg ttgcagcagt tattgaagta aacgctgaaa
    41221 ctgacttcgt tgcaaaaaac gctcaattcg ttgaattggt aaatactaca gctaaagtca
    41281 ttgctgaagg aaaacctgct aacaatgaag aagctcttgc tttgataatg ccttcaggtg
    41341 aaactcttga agctgcatac gtatctgcaa cagcaactat cggagagaaa atctcattcc
    41401 gtcgctttgc attgattgaa aaaacagacg cacaacactt tggagcatac caacataacg
    41461 gtggacgtat cggtgttatt tcagttgttg aaggtggaga cgaagcactt gctaaacaat
    41521 tgtcaatgca catcgcagcg atgaaaccaa cagttctttc ttacaaagaa ttggatgagc
    41581 aattcgttaa agatgagttg gcacaattga atcacgttat cgaccaagac aacgaaagcc
    41641 gtgcaatggt taataaacca gctcttccac acttgaagta tggatcaaaa gctcaattaa
    41701 ctgatgatgt tattgctcaa gctgaagctg acatcaaagc tgaattggct gcagaaggca
    41761 aaccagaaaa aatctgggac aaaattatcc caggtaaaat ggatcgcttc atgcttgata
    41821 atactaaagt tgaccaagct tacacacttc ttgcacaagt ttacatcatg gatgacagca
    41881 agacagttga agcatacctt gaatcagtta acgcttcggt agttgagttt gctcgctttg
    41941 aagttggtga aggtatcgag aaagctgcaa acgacttcga agctgaagtt gcagctacaa
    42001 tggcagcagc cttgaataac taataataga aaggaagcaa tttgcttcct tttttgtata
    42061 gggcttagat ttttcctgaa attgtttttc ccccagtctc actcgattag aataattaaa
    42121 acaaaaagcc ctataataag ggctaagtgc atttaggaga ctatacttca aattcatagt
    42181 aagcgcgtca taacaaggta tctatcctaa ttccccaact tccagtatac tagataaaaa
    42241 ataattatcg gaggaaaggt attgtactat gatgattcaa ctaagtgatt taggtcaagt
    42301 tcacattgtt tgtggcaaga cagatatgag gcagggaata gactcattag cctatgtagt
    42361 taaaacccac tttgaattgg attctttctc cggtcaagtc tttctctttt gtggtggacg
    42421 taaagaccgc tttaaagtcc tttactggga tggtcaagga ttttggctac tatataaacg
    42481 ctttgagaac ggaaaactga cttggctaag tacagaaaag gatgtcaaag ctctcacatc
    42541 tgaacaagta gactggctta tgaaggactt ttctatcact ccccaaatat agtggtttga
    42601 aactagaata gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctgt
    42661 tcttatttca ttttactata aattcatcag aaagtcgtga tttctattga aatgaggact
    42721 ttctttttat actcatctgt tttcacaaag cattctagtc catttccgat taacgatgga
    42781 ctttatcacc tccttctcca gtccttgtat aacatcttgg agttgattca tgacatcttc
    42841 caaaatttga aaggctttat tcttaaatcc acgtttacga atctctttcc acacttgttc
    42901 aatgggttca tctctggtgt gtatggagga ataaaggtaa aaccaatatt agtcggaatc
    42961 tttaacccca attattcacc cctaatctaa aaaccatcca gaatccttgc cttagcttag
    43021 atcctggatg gtttcttttt tcacccaatg ggtgtttttt actagacaaa aaagagtttc
    43081 ccctttatgg tataagtgta gaaaaaaaca caaaaagaaa ggaaactcac atgaacagtt
    43141 taccaaatca tcacttccaa aacaagtctt tttaccaact atctttcgat ggaggtcatt
    43201 taacccagta tggtggtctt atcttttttc aggaactttt ttcccagttg aaactaaaag
    43261 agcggatttc taagtattta gtaacgaatg accaacgccg ctactgtcgt tattcggatt
    43321 cagatatcct tgtccagttc ctctttcaac tgttaacagg
//
LOCUS       DAVLTG010000012        40561 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLTG010000012 DAVLTG010000000
VERSION     DAVLTG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.012"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            64..660
                     /locus_tag="VYN12_000688"
     CDS             64..660
                     /locus_tag="VYN12_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1415118.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            641..1132
                     /locus_tag="VYN12_000689"
     CDS             641..1132
                     /locus_tag="VYN12_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415119.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            1512..3665
                     /locus_tag="VYN12_000690"
     CDS             1512..3665
                     /locus_tag="VYN12_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1415120.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3678..5027
                     /locus_tag="VYN12_000691"
     CDS             3678..5027
                     /locus_tag="VYN12_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1415121.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQVVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            5197..5904
                     /locus_tag="VYN12_000692"
     CDS             5197..5904
                     /locus_tag="VYN12_000692"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1415122.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5961..9686
                     /locus_tag="VYN12_000693"
     CDS             5961..9686
                     /locus_tag="VYN12_000693"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1415123.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSTADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9779..11221
                     /locus_tag="VYN12_000694"
     CDS             9779..11221
                     /locus_tag="VYN12_000694"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1415124.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNTASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11258..12280
                     /locus_tag="VYN12_000695"
     CDS             11258..12280
                     /locus_tag="VYN12_000695"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1415125.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKTLEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12277..12822
                     /gene="purN"
                     /locus_tag="VYN12_000696"
     CDS             12277..12822
                     /gene="purN"
                     /locus_tag="VYN12_000696"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1415126.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12906..13415
                     /locus_tag="VYN12_000697"
     CDS             12906..13415
                     /locus_tag="VYN12_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1415127.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEY
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13440..14987
                     /gene="purH"
                     /locus_tag="VYN12_000698"
     CDS             13440..14987
                     /gene="purH"
                     /locus_tag="VYN12_000698"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1415128.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLGSDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15109..16371
                     /gene="purD"
                     /locus_tag="VYN12_000699"
     CDS             15109..16371
                     /gene="purD"
                     /locus_tag="VYN12_000699"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1415129.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAADTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            16773..17261
                     /gene="purE"
                     /locus_tag="VYN12_000700"
     CDS             16773..17261
                     /gene="purE"
                     /locus_tag="VYN12_000700"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1415130.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17248..18339
                     /gene="purK"
                     /locus_tag="VYN12_000701"
     CDS             17248..18339
                     /gene="purK"
                     /locus_tag="VYN12_000701"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1415131.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18349..18576
                     /locus_tag="VYN12_000702"
     CDS             18349..18576
                     /locus_tag="VYN12_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1415132.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18639..19937
                     /gene="purB"
                     /locus_tag="VYN12_000703"
     CDS             18639..19937
                     /gene="purB"
                     /locus_tag="VYN12_000703"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1415133.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19992..23918)
                     /gene="strH"
                     /locus_tag="VYN12_000704"
     CDS             complement(19992..23918)
                     /gene="strH"
                     /locus_tag="VYN12_000704"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1415134.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDKAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPAEESK
                     ALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24231..24947)
                     /locus_tag="VYN12_000705"
     CDS             complement(24231..24947)
                     /locus_tag="VYN12_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1415135.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25295..27082
                     /locus_tag="VYN12_000706"
     CDS             25295..27082
                     /locus_tag="VYN12_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1415136.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVSRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            27079..27555
                     /locus_tag="VYN12_000707"
     CDS             27079..27555
                     /locus_tag="VYN12_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1415137.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27583..28488
                     /locus_tag="VYN12_000708"
     CDS             27583..28488
                     /locus_tag="VYN12_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1415138.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28475..29290
                     /locus_tag="VYN12_000709"
     CDS             28475..29290
                     /locus_tag="VYN12_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1415139.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29297..29701
                     /locus_tag="VYN12_000710"
     CDS             29297..29701
                     /locus_tag="VYN12_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1415140.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKIRAAESIVKVNDLLASFDDDEDE"
     gene            29995..31161
                     /locus_tag="VYN12_000711"
     CDS             29995..31161
                     /locus_tag="VYN12_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1415141.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31277..32314
                     /locus_tag="VYN12_000712"
     CDS             31277..32314
                     /locus_tag="VYN12_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1415142.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32521..33375
                     /locus_tag="VYN12_000713"
     CDS             32521..33375
                     /locus_tag="VYN12_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1415143.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGIGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            33525..33761
                     /locus_tag="VYN12_000714"
     CDS             33525..33761
                     /locus_tag="VYN12_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1415144.1"
                     /translation="MTNSKYITRLKRSEGQLRGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAI"
     gene            complement(33995..34078)
                     /locus_tag="VYN12_000715"
                     /pseudo
     CDS             complement(33995..34078)
                     /locus_tag="VYN12_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(34112..34204)
                     /locus_tag="VYN12_000716"
                     /pseudo
     CDS             complement(34112..34204)
                     /locus_tag="VYN12_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34240..34536)
                     /locus_tag="VYN12_000717"
     CDS             complement(34240..34536)
                     /locus_tag="VYN12_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1415145.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNTWPGQVE"
     gene            complement(34526..34687)
                     /locus_tag="VYN12_000718"
     CDS             complement(34526..34687)
                     /locus_tag="VYN12_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1415146.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            34757..35521
                     /locus_tag="VYN12_000719"
     CDS             34757..35521
                     /locus_tag="VYN12_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1415147.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            36134..37513
                     /locus_tag="VYN12_000720"
     CDS             36134..37513
                     /locus_tag="VYN12_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1415148.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37527..38192
                     /locus_tag="VYN12_000721"
     CDS             37527..38192
                     /locus_tag="VYN12_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1415149.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38502..39040
                     /locus_tag="VYN12_000722"
                     /pseudo
     CDS             38502..39040
                     /locus_tag="VYN12_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            39140..39517
                     /locus_tag="VYN12_000723"
     CDS             39140..39517
                     /locus_tag="VYN12_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1415150.1"
                     /translation="MIRREDQSVNEQVMIKCIDQQLKVNRLLVDQLDLSQVSHPKMRE
                     YLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAIRKTMLSRLTKH
                     SVLPDRKLSNVVYQITKSVYGFN"
     gene            39633..>40561
                     /gene="pavB"
                     /locus_tag="VYN12_000724"
     CDS             39633..>40561
                     /gene="pavB"
                     /locus_tag="VYN12_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1415151.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSRLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNV"
BASE COUNT        11233 a         7811 c         9395 g        12122 t
ORIGIN      
        1 aaaatggtat atcatttctt atcttttatt aattttagca gcgttgatag agggaattaa
       61 attatgaaaa ttgaaaatga atctaaaagt tatgataaat gtatattgaa aaatatatca
      121 ctagagattg ataagggaat ttacagagtt gaaggagaga atggttcagg aaagagcacc
      181 cttctacaac ttttagctgg gctagagact tttgatagtg gtttaaagaa ttgtgtctcc
      241 aaagatgtac tataccttga taccaatcag cttggggttg ttccatttac tatagaagaa
      301 aatttgcagt tgttgtgtga ttcttttcaa atccatctat catttgagga taaagaacaa
      361 attaatactt tttttgataa taaaatcgga gataactata tgacagcatc tactggaaca
      421 aaattcaaat taggcttatc cttaattttt gctaaaaatt gggattatat ttttattgat
      481 gagactttat caacagtgga tgcaagaagt attgatatga ttgctaaacg cttaatttcc
      541 atgaaagaaa gctctactat tatatatgta tctcataatt tattgaatca agaattgatt
      601 agcaaatctc aaaggatttt aatagaggaa ggacgggttt atgaaatttc aaacaaataa
      661 tagtttatac aaattaatga atctgattat ttatcttttt cttttatatt tgtttattga
      721 tttactgatg aagtcgggaa ttttagatga acaaattgat aaattatctg aactatctaa
      781 tctttttaca attaaaatag aaacaatatt gacagtgatt tctgttgttt tcacatttat
      841 agcaactctt attgaatatg gattttctct ctttctgatt acattatttt ttgataagaa
      901 taagaggaac tttggagata ttcttttatc taaaaatata accttaagtt ttagcatttt
      961 actttgttat ttatttaatc catcggatat aaagtttgcc tatttcagcg tattgacagt
     1021 attactaatt gggataacaa attatgcgag atttaaaaat ttaagattga cagtagtgtt
     1081 ttctgtacca tttttattta atgctataat gtctattata aatagttttt agaaatacta
     1141 aaattttttt ctttacttaa taatgatatg aaatcatttc ggttttgtta acttgtaatt
     1201 cttatatttt ctaggtagaa cgtttgttct gcctattttt ttatccaaaa agtgcagttg
     1261 ggagggagat aggctcattt gggaaggaag tccagttttt gtttagtgat tggggtaaga
     1321 tagttgttat cagatgagtt tatactcttc gaaaatcaaa ttcaaaccac gtcaacgtcg
     1381 ccttgccgta tatatgtgac tgacttcgtc agtcctatct acaacctcaa aacagtgttt
     1441 tgagcagcct gcggctagtt tcctagtttg ctctttgatt ttcattgagt attagggaaa
     1501 aggagatgaa tatgaaattt gggaaacgtc actatcgtcc gcaagtggat cagatggact
     1561 gcggtgtagc ttcattagcc atggtttttg gctactatgg tagttattat tttttggctc
     1621 acttgcgaga attggctaag acgaccatgg atgggacgac ggctttgggc ttggtcaagg
     1681 tggcagagga gattggtttt gagacgcgag ccattaaggc ggatatgacg ctttttgact
     1741 tgccggattt gacttttcct tttgttgccc atgtgcttaa ggaagggaaa ttgctccact
     1801 actatgtggt gacggggcag gataaggata gcattcatat tgccgatcca gatcccgggg
     1861 tgaagttgac taaactgcca cgtgagcgtt ttgaggaaga atggacagga gtgactcttt
     1921 ttatggcacc tagtccagac tataagcctc ataaggaaca aaaaaatggt ctgctctctt
     1981 ttatccctat attagtgaag cagcgtggct tgattgccaa tatcgttttg gcaacactct
     2041 tggtaaccgt gattaacatt gtgggttctt attatctgca gtctatcatt gatacctatg
     2101 tgccagatca gatgcgttcg acactaggga ttatttctat tgggctagtc atcgtctaca
     2161 tcctccagca aatcttgtct tacgctcagg agtatctctt gcttgttttg gggcaacgct
     2221 tgtcgattga cgtgattttg tcctatatca agcatgtttt tcacctccct atgtccttct
     2281 ttgcgacacg caggacaggg gagatcgtgt ctcgttttac agatgctaac agtatcatcg
     2341 atgcgctggc ttcgaccatc ctttcgattt tcctagatgt gtcaacggtt gtcattattt
     2401 cccttgttct attttcacaa aataccaatc tctttttcat gactttattg gcgcttccta
     2461 tctacacagt gattatcttt gcctttatga agccgtttga aaagatgaat cgggatacca
     2521 tggaagccaa tgcggttctg tcttcttcta tcattgagga catcaacggt attgagacta
     2581 tcaagtcctt gaccagtgaa agtcagcgtt accaaaaaat tgacaaggaa tttgtggatt
     2641 atctgaagaa atcctttacc tatagtcgag cagagagtca gcaaaaggct ctgaaaaagg
     2701 ttgcccatct cttgcttaat gtcggcattc tctggatggg ggctgttctg gtcatggatg
     2761 gcaagatgag tttggggcag ttgattacct ataatacctt gctggtttac tttaccaatc
     2821 ctttggaaaa tatcatcaat ctgcaaacca agcttcagac agcgcaggtt gccaataacc
     2881 gtctaaatga agtgtatcta gtagcttctg agtttgagga gaagaaaaca gttgaggatt
     2941 tgagcttgat gaagggagat atgaccttca agcaggttca ttacaagtat ggctatggtc
     3001 gagacgtctt gtcggatatc aatttaaccg ttccccaagg gtctaaggtg gcttttgtgg
     3061 ggatttcagg gtcaggtaag acgactttgg ccaagatgat ggttaatttt tacgacccaa
     3121 gtcaagggga gattagtctg ggtggtgtca atctcaatca gattgataaa aaagccctgc
     3181 gccagtacat caactatctg cctcaacagc cctatgtctt taacggaacg attttggaga
     3241 atcttctttt gggagccaag gaggggacga cacaggaaga tatcttacgg gcggtcgaat
     3301 tggcagagat tcgagaggat atcgagcgca tgccactgaa ttatcagaca gaattgactt
     3361 cggatggggc agggatttca ggtggtcaac gtcagagaat cgctttggcg cgtgctctct
     3421 tgacagatgc gccggtcttg attttggatg aggcgactag cagtttggat attttgacag
     3481 agaagcggat tgtcgataat ctcatggctt tggacaagac cttgattttc attgctcacc
     3541 gcttgactat tgctgagcgg acagagaagg tggttgtctt ggatcagggc aagattgtcg
     3601 aagaaggaaa gcatgctgat ttgcttgcac agggaggctt ttacgcccat ttggtcaata
     3661 gctagaaaga ggagaggatg aaaccagaat ttttagaaag tgcggagttt tataatcgtc
     3721 gttaccataa tttttccagt agtgtgattg tacccatggc ccttctgctc gtgtttttac
     3781 ttggctttgc aactgttgca gagaaggaga tgagtttgtc cactagagct actgtcgaac
     3841 ccagtcgtat ccttgcaaat atccagtcaa ctagcaacaa tcgtattctt gtcaatcatt
     3901 tggaagaaaa taagctggtt aagaaggggg atcttttggt tcaataccaa gaaggggcag
     3961 agggtgtcca agcggagtcc tatgccagtc agttggacat gctaaaggat caaaaaaagc
     4021 aattggagta tctgcaaaag agcctgcaag aaggggagaa ccactttcca gaggaggata
     4081 agtttggcta ccaagccacc tttcgcgact acatcagtca agcaggcagt cttagggcta
     4141 gtacatcgca acaaaatgag accatcgcgt cccagaatgc agcagctagc caaacccaag
     4201 ccgaaatcgg caacctcatc agtcaaacag aggctaaaat tcgcgattac cagacagcta
     4261 agtcagctat tgaaacaggt gcttccttgg ccggtcagaa tctagcctac tctttttatc
     4321 agtcctacaa gtctcagggc gaggaaaatc cccaaactaa ggttcaggta gttgcacagg
     4381 ttgaagcaca gatttctcag ttagaatcta gtcttgctac ttaccgtgtc cagtatgcag
     4441 gttcaggtac ccagcaagcc tatgcgtcag ggttaagcag tcaattggaa tcccttaaat
     4501 cccaacactt ggcaaaggtt ggtcaggaat tgacccttct agcccagaaa atcttggagg
     4561 cagagtcagg taagaaggta cagggaaatc ttttagacaa ggggaaaatt acggcgagtg
     4621 aggatggggt gcttcatctt aatcctgaga ccagtgattc tagcatggtt gcagaaggtg
     4681 ccctactagc ccaactttat ccatctttgg aaagagaagg taaagccaaa ctcacagctt
     4741 atctaagttc aaaagatgta gcaagaatca aggtcggtga ttctgttcgc tatactacga
     4801 ctcatgatgc cgggaatcaa cttttcctag attctactat tacaagtatt gatgcgacag
     4861 ctactaagac tgagaaaggg aatttcttta aaatcgaggc ggagactaat ctaacttcgg
     4921 agcaggctga aaaacttagg tacggggtgg aaggccgctt gcagatgatt acgggcaaga
     4981 aaagttatct acgttattat ttggatcaat ttttgaacaa agagtaatgt tcgtgttttt
     5041 agagttaaat aatttttaaa ctgtgagaaa gattcttctt gcagtttttt ctttacaatt
     5101 tttggaaaac atctgctatt tattcggtta aattcttgta ttttttggtt ttttgtggta
     5161 aaatgtgctc aagtaatacg aaaggcgaac tttaaaatgt caaaacaatt gatctattcg
     5221 ggaaaagcta aagatatcta tacaactgag gatgaaaatc ttattatttc aacttacaag
     5281 gaccaggcga ctgctttcaa cggtgtcaag aaggagcaga ttgcaggtaa gggagtcttg
     5341 aataatcaga tttcatcttt tatttttgag aaattaaatg cggctggtgt ggcgactcac
     5401 tttgtggaga aactttcaga cacggaacaa ctcaataaaa aggttaagat tattcctttg
     5461 gaagtcgtgc tccgcaatta tactgctggt tccttttcaa aacgttttgg tgtggatgag
     5521 ggaatcgcct tggagactcc gattgtcgaa ttttactaca aaaatgatga tttggatgat
     5581 ccatttatca atgatgagca tgtgaaattc ctacagattg cggatgacca gcagattgcc
     5641 tacttgaagg aagaaacgcg tcgtatcaat gaactattga aagtctggtt tgctgagatt
     5701 gggcttaaat tgattgactt taagctagag ttcggttttg acaaggatgg caagattatc
     5761 ttggcagacg aattttcacc agataactgc cgcttgtggg atgctgatgg caaccacatg
     5821 gataaggatg ttttccgtag aggattggga gaactaaccg acgtttatga gattgtttgg
     5881 gaaaagttgc agggtttaaa ataacaacct caaggctgtt tgggaatatt gcaagagctg
     5941 aaataaagga ataagaattg atggataaac gtatttttgt tgaaaaaaag gctgattttc
     6001 aggtcaagtc agagagtttg gttagagagc tccagcacaa cttgggactg tcaagcttga
     6061 aaagtattcg tattgtgcaa gtatatgatg tatttgactt ggttgaggac ttgtttgcac
     6121 ctgcagagaa gcacattttc tctgagcagg taaccgacca tgttttagat gaagtatctg
     6181 tgcaggcgga tcttgctaac tatgctttct ttgccattga aagtctacca gggcagtttg
     6241 accagcgtgc agcttcgtca caggaagcct tgcttttgtt gggaagttcg agtgacgtga
     6301 cagtcaacac agcccaactt tacttggtga ataaagatat tgatgcgact gagttggaag
     6361 ctgtcaaaaa ctacctgctc aatccagttg attctcgttt caaggatatc acgataggga
     6421 ttgccaagca ggagttttca gagtcagaca agaccattcc aaaattgcct ttctttgaaa
     6481 gctatacagc agaagacttt gctcgctaca aggccgaaca agggatggcc atggaagtgg
     6541 atgatttgct ctttatccaa gactacttta agtcaatcgg gcgcgtgcca actgagactg
     6601 aactcaaggt tttggacact tactggtctg accactgccg tcatacgact tttgagacag
     6661 agttgaaaca catcgacttt tcagcttcta aatttcaaaa gcaattgcag tcaacctatg
     6721 acaagtatat tgccatgcgc gaggaattag gtcggtctga aaaaccacaa accttgatgg
     6781 atatggcgac tattttcggt cgttatgagc gtgctaatgg acgattggat gatatggaag
     6841 tctctgacga aatcaatgcc tgctcagttg aaattgaagt ggacgttgat ggtgtcaagg
     6901 aaccttggct cctcatgttt aaaaacgaaa cccacaacca tccaacagaa attgagccat
     6961 ttggtggagc ggctacctgt atcggtggag ctattcgtga tccgttgtca ggccgttcct
     7021 atgtttacca agccatgcgt atttcaggtg ctggtgatat tacagcaccg atttcggaaa
     7081 ctcgtgctgg gaaattgcca caacaagtca tttctaaaac agcaactcat ggttattctt
     7141 catatggtaa ccagattggg cttgccacaa cctacgttcg tgaatacttc cacccaggct
     7201 ttgtagctaa acgtatggaa cttggtgccg ttgttggtgc ggctcccaag ggcaatgttg
     7261 tccgtgaaaa acctgaagca ggtgatgtga tcatccttct cggaggtaaa acaggtcgtg
     7321 atggtgtcgg tggtgcgacg ggctcttcta aggttcaaac agttgagtct gtagagactg
     7381 ctggtgctga ggttcaaaaa ggaaatgcca tcgaagaacg caagattcag cgcctcttcc
     7441 gtaatggcaa tgtcactcgt ctgatcaaga agtccaatga ctttggggca ggcggtgtct
     7501 gtgtggctat cggtgaattg gcagacggtc ttgaaatcga cctcaacaag gtgcctctta
     7561 aataccaggg cttgaatggt acagaaattg ccatctctga atcacaagaa cggatggcgg
     7621 tcgtggttcg tcctgaagat gtggatgcct tcgttgccga atgtaacaaa gaaaatattg
     7681 atgctgttgt ggtggcgaca gtaactgaaa aaccaaatct tgtcatgcac tggaatggtg
     7741 agacaatcgt tgacttggag cgtcgtttcc ttgacaccaa tggtgtgcgc gtggttgtcg
     7801 atgccaaagt tgtggacaag gatgtcaaac tcccagaaga gcgtcaaaca tctgctgaaa
     7861 cactggaatc agataccctt acggttctat ctgacctcaa ccatgcaagt caaaaaggat
     7921 tacagactgt ctttgactgc tctgttggac gctcaacggt taatcaccca cttggtggtc
     7981 gttaccaact cacaccaact gaggcatctg tgcagaaatt gccagttcaa cacggtgtga
     8041 ctcatactgc gtcggtcatt gctcaaggtt tcaacccata tgtagctgaa tggtctccat
     8101 accacggtgc tgcttacgcg gttatcgaag caactgctcg tttggtggct gctggtgcca
     8161 actggtctaa ggctcgtttc tcttaccaag aatatttcga gcggatggac aagcaagcag
     8221 agcgttttgg tcagccagta gccgcccttc taggctctat tgaagctcag attcaacttg
     8281 gcttgccatc tatcggtggt aaggactcca tgtctggtac ctttgaagaa ttgaccgttc
     8341 cgccaacctt ggttgccttt ggggtgacga cggcagatag ccgtaaggtg ctctctccag
     8401 aatttaaagc tgttggggaa aatatctact acatcccagg tcaagccctc tctgcagaga
     8461 ttgattttga cttgattaag aaaaattttg ctcagtttga agcaagccaa gctgaccata
     8521 aagtgacatc tgcatcagct gtcaaatacg gtggtgtagt tgaaagtttg gctcttgcta
     8581 cctttggaaa ctatattggt gcagaggtga ccttgcctga acttaaaaca gctttgacag
     8641 ctcaattagg cggctttgtc ttcacatctc ctgaagaaat tgctggagta gagaagattg
     8701 gacaaacgaa agcagacttt acactgactg tcaacggtgt gaagctagat ggacacaagc
     8761 ttgacagtgc atttcaaggg acattggaag aagtttaccc aacagaattt acccaagcga
     8821 aagaactaga agaagtacca gctgtggcat cagatgttgt gattaaagcc aaagaaaagg
     8881 ttgaaaaacc tgtggtttac atcccagtat ttccaggaac caactcagaa tatgattcag
     8941 ctaaggcctt cgaaaaagaa ggtgcagagg tcaatttggt gccattcgtg accttgaatg
     9001 aagaagctat tgtcaagtca gttgaaacta tggttgacaa tatcgacaag actaatattc
     9061 tcttctttgc cggtggattc tcgactgcgg atgaaccaga tggttcagct aagtttatcg
     9121 tcaatatcct gcttaatgaa aaagtgcgtg tggctattga tagctttatc gcccgtggtg
     9181 gcttgattat cggtatttgt aatggattcc aagccttagt caaatcgggt ctcctaccat
     9241 acggaaactt tgaagatgct aacagtacta gtccaaccct cttctacaat gatgccaacc
     9301 aacacgtggc caagatggtg gaaactcgca ttgccaatac caactcacca tggttggctg
     9361 gtgtgcaagt gggcgatatc cacgctattc ctgtttcgca cggtgaaggg aagtttgtcg
     9421 tgacggctga ggaatttgca gagctccgtg acaatggaca aattttcagc caatacgttg
     9481 actttaacgg taaaccaagt atggattcta agtacaatcc gaatggttct gtccatgcca
     9541 tcgaaggaat taccagcaag aatggtcaaa tcatcggtaa gatgggccac tcagaacgtt
     9601 atgaggatgg tcttttccaa aatatcccag gcaataaaga ccaacacctg ttcgcatcag
     9661 cggttaaaca tttcactgga aaataagact tacagatttt ctaatagata gtatcagtaa
     9721 tgtaaaagtc atgtaaatct agctcttgat gattacaaat gaaaattagg tataaaaaat
     9781 gacatacgaa gtaaaatctc ttaatgaaga atgtggtgtt ttcggtattt ggggacatcc
     9841 agatgctgct aagttgacct attttggact ccacagtctt caacaccgtg gtcaggaggg
     9901 ggcaggaatc ctctccaacg atcaaggaca actgaagcgc catcgtgaca tggggctttt
     9961 atcagaagtt ttcagaaatc cagctaattt ggataaattg acaggagctg gtgcgattgg
    10021 gcatgtgcgt tatgcgactg ctggcgaagc ttctgtagat aacatccagc ccttcctctt
    10081 ccgttttcac gatatgcagt ttggcttggc tcataatgga aatctgacca atacagcctc
    10141 tctcaagaaa gaactggaac aaagaggagc aattttcagc gcgacttcgg actctgaaat
    10201 cttggctcac ctcattcgtc gcagtcataa tcctagcctg atgggcaaaa tcaaggaagc
    10261 gctcagcctt gtcaaaggtg gttttgccta tatcttgctg tttgaggaca agttgattgc
    10321 ggctcttgac cctaatggct ttcgtccgct ttctatcggg aaaatggcca acggagcggt
    10381 ggttgtttcc tctgaaacct gtgcttttga ggtcattggt gccgagtgga ttcgtgattt
    10441 gaagccaggt gagattgtga tcattgatga cgagggcatt cagtatgaca gctatacaga
    10501 tgatacccag ttggcgattt gttctatgga gtatatctac tttgcccgcc ctgattctaa
    10561 tatccacggt gtcaatgtcc atacggcacg taagagaatg ggagcgcaat tggcgcgaga
    10621 atttaagcat gaggcagata ttgtagttgg tgtgcccaat tcttccctaa gcgcggctat
    10681 gggatttgcg gaagaatcag gcttaccaaa tgaaatgggt ctgatcaaaa accaatacac
    10741 ccagcgaact tttatccaac cgactcaaga attgcgggag caaggagtgc ggatgaaact
    10801 gtctgctgtt tcgggtgttg tcaaaggcaa acgtgtggtc atggtggatg attccattgt
    10861 acgtggaaca acctctcgtc gtatcgttca gctcttgaaa gaagcgggtg cgactgaggt
    10921 tcacgttgcc attggaagtc ctgcactagc gtatccatgt ttctacggga ttgatatcca
    10981 gacccgtcag gagctgattg cagccaatca tacggtcgaa gaaactcgcc aaatcattgg
    11041 tgcggacagt ctgacttatc tttcaattga tggcttgatt gagtcgattg gtatcgaaac
    11101 agatgcgccg aacggtggtc tctgtgtcgc ttactttgac ggtgactacc caacgcctct
    11161 ttatgactac gaagaagact atcgtagaag tttggaagaa aagaccagtt tttacaagta
    11221 ggcgacagat tctccattaa agaaaaggaa aaaacaaatg acaaataaaa atgcatatgc
    11281 ccagtcgggt gtggatgttg aagcgggtta tgaagttgtt gaacggatta aaaagcacgt
    11341 ggcccgtacg gagcgtgcag gtgtcatggg agctcttggt ggctttggtg gtatgtttga
    11401 cctttccaag actggggtta aagaacccgt cttgatttca gggactgacg gtgtcggaac
    11461 caagctcatg ttggctatca agtacgacaa gcacgatacc atcgggcagg actgtgtggc
    11521 catgtgtgtc aacgacatca ttgctgcagg tgcggaaccc ctctattttc tcgactacgt
    11581 agcgacaggg aagaatgaac cagctaagct agaacaagtg gttgctggtg tggcagaagg
    11641 ttgtgtgcag gctggtgctg ccctcatcgg tggggaaacg gctgaaatgc cgggcatgta
    11701 cggcgaagac gactatgact tggctggttt tgcggtcggt gtggctgaaa aatctcaaat
    11761 cattgacggt tcaaaggtgg tagagggaga tgttcttctc ggacttgctt caagtgggat
    11821 tcactcaaat ggttactctt tggttcgtcg tgtctttgcg gattacacag gtgaggaagt
    11881 cctaccagaa ttggaaggca agaaacttaa ggaagttcta cttgagccga ctcgtatcta
    11941 tgtcaaggct gtcttgccgc tcatcaaaga agagttggtc aacggcattg cccacatcac
    12001 aggtggtggc tttatcgaaa atgtccctcg tatgtttgca gatgacctag ctgctgaaat
    12061 tgatgaaagt aaagttccag tgcttccaat tttcaaaacc cttgaaaaat acggtcagat
    12121 taaacacgaa gaaatgtttg aaatcttcaa tatgggtgtg ggactcatgt tggcggtcag
    12181 ccctgaaaat gtagagcgtg taaaagaatt gttggatgaa gcagtctatg aaattggtcg
    12241 catcgtcaag aaagaaaacg aaagtgtcat tatcaaatga aaaaaatagc ggtttttgcc
    12301 tctggtaatg gctcaaattt tcaggtgatt gccgaagaat ttccagtgga gtttgtcttt
    12361 tcagaccatc gtgatgccta tgtgcttgag cgtgcaaagc agctcggcgt tctgtcctat
    12421 gcttttgaac tcaaggagtt tgagagcaag gcagactacg aagcagccct tgtcgaactc
    12481 ttggaagaac accagattga cttggtttgc ctagcaggct acatgaaaat cgttggacca
    12541 accttattgt cggcttatga aggtcggatt gtcaacattc atccagccta cttgccagaa
    12601 tttccaggag ctcatgggat tgaggatgct tggaatgctg gcgtgggtca gtctggtgtg
    12661 accattcact gggtggattc gggtgtggat acaggccagg tcatcaaaca ggttcgtgtg
    12721 ccacgactag ctgatgatac cattgacaga tttgaagctc gcatccatga agcagagtac
    12781 aggttgtatc cggaagtagt gaaggctcta tttacagatt gactttttga tgattcatat
    12841 gatatctttg attttaaatt ggagtcagtg tttgttgaag acggcttcaa acggaggtat
    12901 ttgtaatgtt agaatctaaa aaaacaactc gatatgtatt ttatgtctat ctgatgttat
    12961 taacttgggg aatcttattt aagtttgaaa caaatcctga atttatagca tttttcttag
    13021 ctccaaggta tatcaattgg attccatttt cagaaccact aatagtcgat ggaaaaattg
    13081 tttttgctga aatgttattt aatctgattt tctttattcc attaggtgtt tgtttccctt
    13141 tgataaaaac taatttatct agtttaagaa tagtcgggac aggtttcttg attagtttat
    13201 tgtttgagta cttacagtat attttagcaa taggtataac agatataacg gatttgactt
    13261 taaatacgct aggtgtctgt gtaggcttac tgatttatca aatttttata agagtgttca
    13321 aatcacagac tagaaaatgg atcaatatct taggtatgct tagccttggt tttgcttatc
    13381 ttgttttact gttactgcat ttaattggtg tttaactaat gattaaaaag gagaatataa
    13441 tgactaaacg cgtcttaatc agcgtctcag acaaagcggg cattgttgaa tttgcccaag
    13501 aactcaaaaa acttggttgg gagattatct caacaggtgg aactaaggtt gcccttgata
    13561 atgctggggt ggataccatt gctatcgatg atgtaactgg tttcccagaa atgatggacg
    13621 gtcgtgtgaa gaccctccac ccaaatatcc acggagggct tctcgctcgt cgtgacttgg
    13681 atagccactt ggaagcggct aaggacaaca agattgagct cattgacctt gtggtggtca
    13741 acctttaccc atttaaggaa actatcctta aaccagatgt gacttatgct gatgcagttg
    13801 aaaatatcga tattggtggg ccgtctatgc ttcgttcagc agcgaaaaat catgccagtg
    13861 ttacagttgt ggtagatcct gctgactacg ctgtggtttt ggacgaattg gcagcaaacg
    13921 gcgaaacctc ttatgaaact cgccaacgtt tagcagccaa agtatttcgt cacacagcgg
    13981 cttatgacgc cttgattgca gaatacttca cagctcaagt gggtgaaagc aagcctgaaa
    14041 aactcacttt gacttatgac ctcaagcaac caatgcgtta cggtgagaat cctcaacaag
    14101 acgcggactt ttaccagaaa gctttgccta cagattactc tattgcttca gccaaacagc
    14161 tcaacgggaa agaattgtca tttaataata tccgtgatgc agatgctgct atccgtatca
    14221 tccgtgactt caaagatagt ccaaccgttg tggctctcaa acacatgaat ccatgtggaa
    14281 ttggtcaagc tgatgacatc gagactgctt gggactacgc ttatgagtct gacccagtat
    14341 ctatctttgg tgggattgtc gtcctcaacc gtgaggtgga tgctgcgaca gctgagaaga
    14401 tgcacggcgt tttcctcgaa atcatcattg caccaagcta tacggatgaa gcgctagcca
    14461 ttttgatcaa taaaaagaaa aacttgcgta tccttgcctt gccatttaat gctcaagagg
    14521 ctagcgaagt ggaagcagaa tacacaggtg tagtcggtgg acttctcgtg caaaatcaag
    14581 acgtggtcaa ggaaagccca gctgactggc aagtggtgac caaacgtcag ccaactgaga
    14641 cagaagcgac tgctcttgag ttcgcttgga aggctatcaa gtacgtcaaa tcaaatggta
    14701 ttatcgtgac caacgaccac atgacacttg gtgttggtcc aggtcaaacc aaccgtgtgg
    14761 cttctgttcg ccttgccatt gaccaagcca aagatcgtct gaacggggcg gtccttggtt
    14821 cagatgcctt cttcccattt gcggataacg tggaagaaat cgccaaagca ggaattaagg
    14881 ccatcatcca gcccggtggc tctgtccgtg accaagaatc catcgaagca gcggataaat
    14941 acggcttgac tatggtcttt acaggtgtga gacattttag acattaagaa gataaaaggg
    15001 aagaaaacag tttctttcct tttttggctt aaaatgctaa ctgaaacaag attaaaacga
    15061 acttttttga tataatgttg gtaaataatt cgcaaaagag gttgaggaat gaaactgctt
    15121 gttgtcggtt ctggtggtcg tgagcatgcg attgctaaaa agttacttga atcaaaagac
    15181 gtggaaaaag tctttgtagc tcctgggaat gacggtatga ctctggatgg tctggaattg
    15241 gtaaatatat ctatttccga acattataaa ttgattgact tcgcaaaggc caacgatatt
    15301 gcttggacct ttatcggtcc agatgacgcc cttgcggctg gtatcgtgga tgatttccat
    15361 gcagctggtc tcaaagcctt tggtccgaca agattggcag cggagctgga gtggtccaag
    15421 gatttcgcca aggaaatcat ggtcaaatat ggtgtttcga cagcagccta tggcacattt
    15481 tcagatttcg aggaagcaaa ggcctatatc gaaaagcatg gtgcgcctat cgtagtcaag
    15541 gcggatggct tggcgcttgg gaagggtgtc gtcgttgctg agacggttga gcaagcggtc
    15601 gaagccgctc atgagatgct tttggacaat aaatttggtg actcaggtgc gcgcgtggtt
    15661 attgaggaat tccttgaagg agaggaattt tcactctttg cctttgtcaa tggtgataag
    15721 ttctacatca tgccaacggc tcaggaccac aaacgtgcct acgatggcga caaagggcct
    15781 aacacgggtg gtatgggtgc ctatgcgcca gttccacact taccacagag tgtagttgat
    15841 acagcggctg acaccattgt caagccagtt ctagaaggga tgattaaaga aggtcgccct
    15901 tatctgggag ttctttacgc agggcttatc ctgacagctg atggaccgaa agtcattgag
    15961 ttcaacgctc ggttcggaga tccagaaact cagattatct tgcctcgctt gacctctgac
    16021 tttgctcaaa atatcacaga tatcctggat agcaaggagc caaatatcat gtggacggac
    16081 aagggtgtga ctctgggtgt ggttgtcgca tccaagggct acccgctaga ctatgaaagg
    16141 ggcgttgagt tgccagccaa gacagaaggc gatgtcatca cctactatgc aggggctaag
    16201 tttgcggaaa atagcagagc actgctctca aacggcggac gagtttatat gctcgttacc
    16261 acagcagata ccgtcaaaga agcccaagcc agcatctacc aagaactata ccaacaaaaa
    16321 atagaaggac tcttctaccg aacagatatc ggaagcaagg caattaagta aagatataag
    16381 aataacgcgc cgtagtcgcc aaacacgata atggtcgtcg tggtgaaaag accagaacag
    16441 tgaatgttct ggtcagggga aacttggaga ccttaggctc aaagtttagg aatgaaaccg
    16501 aaggtttgct tccgcctcca tcacctaaga ccattatcaa aaagaaaaat aaaaattcac
    16561 aaaatacgtt aatgatcgta tggtttgcga gcgttagcga gctaatatag aacaatcacc
    16621 gccgttgtga aagaacgatt ggatgataat ccaatcgttc agggaaattg gaagaccttg
    16681 ggtttccaat ttaggcatga gacacctttg gtggctgctg ccgtccctca caagctaagg
    16741 tgattgttga aaaagaggaa aaaggagaag aaatgaaacc agtaatttcc atcatcatgg
    16801 gctcaaaatc cgactgggca accatgcaaa aaacagcaga agttctagac cgcttcggtg
    16861 tagcctacga aaagaaagtt gtttccgcac accgtacacc agacctcatg ttcaaacatg
    16921 cagaagaagc atatagccgt ggtattaagg tcatcatcgc aggtgctgga ggcgcagccc
    16981 acttgccagg aatggtagct gccaaaacaa cccttcctgt cataggggta cctgtcaagt
    17041 ctcgtgctct tagtggagtg gattcactct attctatcgt tcagatgccg ggtggggtgc
    17101 ctgttgcgac catggctatc ggtgaagctg gagcgactaa cgcagctctc tttgccctcc
    17161 gtctcctctc tgtagaagat aagtccattg cggatgcact tgccaacttt gctgaagaac
    17221 aaggaaaaat cgcagaggag tcgtcaaatg agctcatcta aaacaatcgg aattatcggt
    17281 ggcggtcaac tgggtcagat gatggccatt tctgctatct acatgggcca caaggttatc
    17341 gcgctggatc ctgcggcgga ttgcccggtc tctcgtgtgg cggaaatcat tgtggcacct
    17401 tataacgatg tagacgccct ccgtcagttg gcagaccgtt gcgatgtcct cacttacgag
    17461 tttgaaaatg tcgacgctga cggtttggat gccgttatca aggatggaca actccctcaa
    17521 gggacagacc tgctccgcat ttcgcaaaat cgtatttttg aaaaggactt tttgtcaaac
    17581 aaggctcaag tcactgtggc accctacaag gtcgtgactt ctagcctaga cttggcagat
    17641 atcgacttgt cgaaaaacta tgtcctcaag actgcgactg gtggctacga tggtcatgga
    17701 caaaaggtta ttcgttcaga agtagacttg gaagcagcct atgcgctagc agaatcagca
    17761 gactgcgtct tggaagaatt tgtcaacttt gcccttgaga tttctgtcat cgtgtcagga
    17821 aatggcaagg aggtgacgtt tttcccagtt caggaaaata tccaccgcaa caatatcctg
    17881 tctaagacca tcgtaccagc ccgcatttct gaaagtctag tagacaaggc taaagctatg
    17941 gcagtgcgaa tcgcagaaca actcaacttg tctggaactc tctgtgtgga aatgtttgcg
    18001 actgatgatg acgttattgt caatgaaatc gccccacgac cacataactc tgggcactat
    18061 tctattgaag cctgtgattt ctctcagttt gacacccata ttctcggtgt tctcggagca
    18121 ccattaccag tcatcaaact ccatgcgcca gccgttatgc tcaatgtcct aggtcaacac
    18181 gtcgaggctg ctgaaaagta tgtcgcagaa aatccaagcg cccacctcca catgtatggt
    18241 aaaatagaag caaagcataa tcgtaagatg ggacatgtga ccttgtttag tgatgtaccg
    18301 gatagtgtgg atgagcttgg ggaagggatt gatttttagg acaagtctat gatacaaatt
    18361 atcgttaata catttattga aaaggataag actggagcag ttgttgaagt gttgtatgcc
    18421 agtgctgacc aagataaggt acaagctaaa tatgaagaac tagctgcaca ataccccgaa
    18481 aattatttag ctatctatga tgtaccgctg gatacggatt tgaatacact agatcattac
    18541 ccgtctgtgt ttattgaaaa agaggagttt gagtagaaat cttggtttac ctagatagct
    18601 tattcccaac agcttaagaa gaaaggaaaa attaacacat gatcaaccgt tactctcgcc
    18661 ctgagatggc gaatatttgg agtgaagaaa ataaataccg tgcttggctt gaggtggaaa
    18721 tcctctctga cgaggcatgg gctgagttgg gggaaatccc taaggaagat gtggctttga
    18781 ttcgcaagaa ggcggacttt gacatcgacc gtattttgga aattgagcag gagacgcgcc
    18841 acgatgtggt ggctttcacg cgtgcggttt ctgagactct tggtgaagag cgcaagtggg
    18901 ttcactatgg gttaacttct accgacgtgg tggatactgc ttatggttac ctctacaagc
    18961 aggccaacga catcatccgt cgtgaccttg aaaacttcac taatatcatc gctgacaagg
    19021 ccaaggagca caagttcacc atcatgatgg ggcgtactca tggtgtgcac gctgagccga
    19081 caacctttgg tcttaaattg gcaacttggt acagcgaaat gaaacgcaat atcgagcgtt
    19141 tcgagcatgc agctgctggt gtagaagctg gtaagatttc tggtgcggtt gggaactttg
    19201 ccaatatccc accatttgta gaggagtatg tctgcgataa acttggcatc cgtgcccaag
    19261 aaatctctac acaagtcctt cctcgtgacc ttcacgctga gtactttgcg gttcttgcca
    19321 gcattgcgac ttcaatcgaa cgtatggcga ctgagattcg tggtctacaa aaatctgagc
    19381 aacgcgaagt agaagagttc tttgctaaag ggcaaaaagg gtcttcagca atgcctcaca
    19441 aacgcaaccc aatcggttct gaaaatatga ctggtctggc gcgtgtcatt cgtggtcaca
    19501 tgattacggc ttatgaaaac gtcgctctct ggcacgaacg cgatatttct cactcatcag
    19561 ctgagcgtat catcacacca gatacgacca ttttgattga ctacatgctc aaccgttttg
    19621 gaaatatcgt caagaacttg acagtcttcc cagaaaatat gatccgaaac atgaactcga
    19681 cttttggtct tatctttagc caacgggcta tgttgacatt gattgaaaaa ggcatgaccc
    19741 gtgagcaagc ctatgacttg gtgcaaccaa aaacagccta ctcttgggac aaccaagtag
    19801 actttaaacc acttcttgag gcagattcag aagtaacatc acgtctcaca caagaagaaa
    19861 tcgatgaaat cttcaaccca gtttattaca ccaaacgagt ggatgatatc tttgaacgtc
    19921 ttggactagg tgattaatta aaaaataaac agcgagcttc aatctcgctg tttatttttt
    19981 atcgaaaaga cttagtcttc ttttctttta gtgagtccat aggctgctag tgtggccatg
    20041 agtcctgcga ctactagtcc tgcagaatcg tgagttcctg tttcaggaag ttttttctct
    20101 attaccacag gagctggatc ttgaggaaga gctttgcttt cctcagcagg agctggttgg
    20161 cttaggattt ctagttttgg tttttcttca gcaatagcgg cttgtccgtt ttcatcgcct
    20221 acatgtgtta ccatagttcc gacttcgact atttgagtaa cggcttcctg tgctacgaca
    20281 ctatttacaa gtgttttcac ttccttacca tcggcagaag tgctcacaga gtagaagttg
    20341 ctacgatgtc cattgacgcc cttagtaatg acttgtgttt ttcctttgag taagagtgga
    20401 ttttcacgag tcactgtggt aaatggaatt tcttcttctt ggatatccag tctaggtttt
    20461 acctcagtag ttggtgcaag accactttca tcacccttgt gagttacagg agcgccaact
    20521 tcaaccactt ggtttataac ttctttggtt acctggctat caaggactgt ttctgttgtt
    20581 tttccatttt cagtgagtac agagatgtaa tgagttcgtt cacctttgac tcctgctgtg
    20641 ataatatttt cctgaccagc tgggaggtta ggattttctt tcttgataac ttcaaatgga
    20701 atttcttcag ttcttgtgat gagttctggt ctggtttcaa cattggcagc cacttcattt
    20761 tcatctaggc ttcctgaatg agttgcagct ggtttgaggc cttgaagagc ggcttttagg
    20821 ttggctacaa gtgtgtcaag ctcagcttgt ttattacggt tgaggttgta atttagagct
    20881 gttttagctg cgtcaagggc ctcaagactt tctttactat atccttctaa gtttgtagga
    20941 attttagcta attcttcgcg gagagcatta taattagcac ggaagtagtc tttgttgtgg
    21001 tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct tgtattcagc gcttggtcta
    21061 tctgcccaga ttgaaagcat acttccgact gttggaagat ctacttcagg atatttggta
    21121 gaagctagtt gattgaatgg aactttacca gaattttcaa ctgcttttga aagagggtaa
    21181 gcttcatctt gtttgtgatt gcctataaca taataccagt caccgttggt attcaagaac
    21241 ttataaccct tgcttgctag gtattgaggt gatgcgaggt tgtatcccca ccagccttta
    21301 gaccagtaag aaatcaagac atctttgtca aactgaacat cgtccttgtc ttcatagtag
    21361 aagccatcgt tgaaggccat tggttgaagc cctctttctt tggccatagc tgcgagggtg
    21421 ttggcatatt cggcaaattt gccatagagt tgataccact tgaggtagta ccagccttgg
    21481 gcactagtcg catcgttggc gtattcgtca gtaccaaagt tgaaaatctt tgttttacct
    21541 gcaaagaagt ccatgtattt accgatgagg gcttttacaa agttcatcgc ttcttcgttt
    21601 ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg cttgaggatt tttaatacct
    21661 aatttttcca tggcaaccag catagcatcc atgtgacctg gactgttaat agctgggatg
    21721 agaccaatgt ccttagattt agcgtattca attagctctg tcacttctgc ctgtgttagt
    21781 gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt cgataatagc ttttttaacg
    21841 tcatcactag cataggtttt tccgttggca gtaatggtca tatcattgag tagaaagcga
    21901 agtccgtcat ttcctagaag gagatggaca tcagaatatc cgagctcact ggccttgtct
    21961 acgatgcgtt tgagctggtc cagagtaaag tatttgcgtc cagcatcgat tgagattacc
    22021 ttgtttttgg caagtttttc aacctcacgt ttagcttctt cttctttttg agcttcaggc
    22081 gtgagggtca agttgttgac agtttcttga agtttagcaa tggctttatc aatcgtatct
    22141 tgttgggcac ggctaaggtt gctatcgaga gagcgaatag ctttttcagc ttcttttacg
    22201 gccgtgacgc tttctgcagt ataacggttc aggtcttttg gtacctcgtt aagtgcttgc
    22261 tctgcagatt cataatcagc tgcgaagtat tcagcgttgg catttgcaaa atgacgcatg
    22321 agtttgaaga ggcgtgatgg tgaataacgt gcagatggag tgtcagccca agcagctacc
    22381 ataccaccga tgattgggat atcagctcct tctgtttttg gtacagaagt gattggtgtg
    22441 tttttaatac cattgagccc ctgatcgaga ttgtaccagc cttggccatc agcgtttcgt
    22501 ccaagaacgt agtaccaagc atcattggta ttaaggattt ggtgaccttt ttcagctagt
    22561 agtttagaag aagcgacatc gtagcctccc caaccaccag tccacataga aacgatgatg
    22621 tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt agataccgtc gttaaaggcc
    22681 attggtttga gaccgtgcga ttttacaata cgagcgaggt cattggcgta ggcaataaat
    22741 ttttcatagc cttttacagg gtagccttcg tttggatagt atttatcagc ttgaagcaca
    22801 ctccaacctt tagcatctgt cgcatcattg gcatattcat caagtccgat gttgaagatt
    22861 tcagtctttt tcgcgaaata agcagcatac ttgtcgataa gggcttttgt aaaagcgaca
    22921 gcttgttcgt tgtcaagatc gacagtacgg gctgatttct tcccaaaata gctaaagtta
    22981 gggttttgga ttcccaattc tttcatggca ttgagaatcg catccatgtg tccaggacta
    23041 tttactgtcg gaatgagacc gataccttta tctttggcat agttaatcag atctgtcatt
    23101 tgactttctg ttaagtgatt gccgtttgga tcgttgtaat aatcatttgt acctttttca
    23161 atggcgcgtt tgacatcgtc actggcatag gtcttgccgt tagctgtgat gctcatatcg
    23221 tccaacatga aacggagtcc atcatttccg actaataggt gtaaatcagt gtagccataa
    23281 tgtttcgctt tatcgatgat ttccttgagc tgttctggtg agaaatattt acgtccagca
    23341 tcaatagaaa caattttctt tttcgctagt ttttcattta cagttgcagc acgttccttt
    23401 cctgtctctg tttccggttt gtcagcctct gctttcgctt catctttttt agctggttta
    23461 tccttgtcag tcttgtctgt atttgactct ttagaatcaa cctctttcgc ttcttccttt
    23521 ttagggctag cttcttcttc ctttttatta gcagtttctt tttcagcaga agttggagtt
    23581 accacctctg ctttatcact aggagttgaa ctaacttcct cttgtggttt ttcttctgtt
    23641 tttggaagac tagctacctt atcagtagct ggagtttctg tttctacagt ttttggagcc
    23701 tctggttgaa gctctgcttt aggtgtttcc tcagtccgat tttcggatga ttgaggggaa
    23761 tcagaaaccg tatggatggt cggttggttt tctgtagtag taggagtaac tccatcggct
    23821 gcaacagtct gtgcttggaa ggcaaatcca attagaacag aagctgctcc tacagcgtat
    23881 ttacgaatag aaaaacgctg ttgtttttca tgtttcattg caaaacctcc tgattgcatt
    23941 gttatattga tagcgattat ataaatcaac gcccttattt tatttcttat attaacgaga
    24001 gtcaagagga gatgacaaaa actataataa gtataaaaaa atataaaatt taaacttaag
    24061 atttcagatt ggtcggaaaa aatgcatata tatctagtat aatttttggt tctatttcta
    24121 taaaatattc cacaaattat agaatcttcc aaaaataggt aagcgctacc tttttggtgt
    24181 ggtataataa gcatagaaaa agcccgagcg attaggctca ggctttcttc ttagtgatca
    24241 cggtcacatg agatgaattt aatcttgtag taatcagatc gtttgtaagt ttcactgtat
    24301 tctaaaactt ggccagttga ttcgagtttg gtgattttag tttgtaggac agtagggaat
    24361 tgttcatcga ctccgaggac tgaagccgca tgttctggag ttggaaagac tatttcgttg
    24421 atttcttcaa agtgttcatc attcatgtga atgtggtagt ctaacttgaa acgattatag
    24481 atagaactat agtattcaag gtttggataa tttgcgttga tatattgttc tgggatgtag
    24541 gatgtatggt agatataaac gacaccgttt gattcgcgga tacgttcaat cttgtagtag
    24601 aattgatcgc cgcgtagacc caatttttcc aagtaaacaa gcttgtttcc gcgttcaatt
    24661 gaaagaacag ttaccttatc atctttagca ttgaagagtt caatatctga aaactctaca
    24721 agcttgtgtt tgcgtgcacg tgaaacgaag gttccttttc cttgttggcg gacaatatag
    24781 ccatctttgg caaggtcgtt taaggcgcga acaactgtga tagagctgac atcgtacatt
    24841 gaaatgagtt ctgcttcagt gtaaaattta tctccactgc taaactgccc agagatgatt
    24901 ttatttttta attcgtcttt tatgtattga tatttgggaa ttgccatatt tttacctcta
    24961 ttttccttct ccatagaaaa ttttaccata aaagcgaaaa aaatagtagt cttttgaata
    25021 aaaaattaga ataatagttt gaaaaattaa gcgatatagg gattgctcat attttatcaa
    25081 tgtattctat acaaaattat tttaggtcct atattccgaa tttaaagagc gtttgaaatg
    25141 ggtctaaaaa tgtttgaaac taattgaatg tgtgtataat agtaaaaatg cagtaaatat
    25201 cccgacaatt tctattgaca attcaaacag attggtttat aattaatata acaacaaatg
    25261 aaagcgcaaa ctttcgcggt cggaaggtag ttttatgaca cgatttgaga tacgagatga
    25321 tttctatctc gatggaaaat catttaagat tttatctggt gccattcatt attttagggt
    25381 tcctccagag gattggtatc attcgctcta taacttgaag gctcttggtt ttaatacggt
    25441 agagacttat gttgcttgga atttacacga gcctcgtgaa ggtgagtttc attttgaagg
    25501 tgatctggat ttagagaaat ttctccaaat agcgcaggat ttgggtctct acgcaattgt
    25561 gcgtccgtct ccatttatct gtgcggaatg ggaattcggt ggcttaccag cttggctctt
    25621 gaccaagaac atgcgaattc gctcatccga cccagcatat atcgaggcag ttggtcgcta
    25681 ctatgatcag ttattgccaa gactggtgtc tcgtttgttg gacaatggtg gcaatattct
    25741 catgatgcag gttgaaaatg agtatggttc ttacggagaa gataaggctt acctgagagc
    25801 gattcgacag ctaatggaag agtgtggcgt aacctgtccc ctctttacat cagatggtcc
    25861 atggcgagct actctgaaag ctggaacctt aattgaagag gacctctttg taacaggaaa
    25921 ctttggttct aaggcacctt acaacttttc gcagatgcag gaattctttg atgaacatgg
    25981 taagaaatgg ccactcatgt gtatggagtt ctgggatggt tggttcaatc gctggaaaga
    26041 accgattatc acacgggatc ctaaggaatt ggcagatgca gttcgagaag ttttggaaca
    26101 aggctccatc aatctttaca tgttccacgg tggtacaaac tttggtttca tgaatggttg
    26161 ctcagctcga ggaactttgg acctgccaca agttacgtct tatgattacg atgcccttct
    26221 ggatgaagaa ggaaatccaa ctgctaaata tcttgcagtc aagaagatga tggcaacaca
    26281 tttttcagag tatccgcagt tggaaccact ctacaaagag agtatggagt tggatgctat
    26341 tccactagtt gaaaaagttt ctttgtttga aaccttagat agcttgtcaa gtcctgtaga
    26401 aagtctctat cctcaaaaga tggaggagct gggacaaagt tatggctacc tactttatcg
    26461 aacagaaaca aactgggatg cagaagaaga aagacttcgt atcattgatg gtcgagatag
    26521 ggcccagctg tatgtcgatg gtcagtgggt taaaactcaa tatcagacag agattgggga
    26581 agatattttt tatcaaggta aaaagaaagg gctatctagg ttagatatct tgatagaaaa
    26641 tatggggcgt gtcaactatg ggcataagtt cttagcggat acgcaacgta agggaattcg
    26701 gacaggggtc tgtaaggatc tgcatttctt actaaactgg aaacactatc cactcccact
    26761 agacaatcct gagaaaattg atttttcaaa aggatggact caaggacaac cagcctttta
    26821 cgcttatgac tttacagtcg aagagccaaa agatacttac ctagacttgt ctgagtttgg
    26881 taagggggtt gcctttgtca atgggcagaa tctaggacgt ttttggaacg ttggcccaac
    26941 tctctcactt tatatccctc attgctatct caaggaaggt gccaaccgca tcattatctt
    27001 tgaaacagaa ggtcaatata aagaagagat tcatttaact cgtaaaccta cactaaaaca
    27061 tataaagggg gaaaacttat gacaattgta ggatgccgta ttgatggacg tttgatccac
    27121 ggacaagtag ccaatctttg ggctggaaaa ctaaatgttt cacgcattat ggttgtagac
    27181 gacgaagttg tcaacaacga tattgaaaag agtggtttga aacttgcgac accaccaggt
    27241 gtgaaattga gtattttgcc agttgagaaa gctgcagcca atattcttgc tggcaaatac
    27301 gatagccaac gtctctttat cgtggctcgt aaaccagacc gcttccttgg tttggtagaa
    27361 gcaggtgtac cacttgaaac ccttaatgtt gggaatatgt ctcaaacacc agaaactcgt
    27421 tctattacac gttctatcaa cgtagtagac aaggatgtgg aagacttcca caaactggca
    27481 gaaaaaggtg ttaaacttac tgctcagatg gttccaaatg atccaatttc agactttttg
    27541 agcttattaa aataggaaaa aattttttag gaggtcattg ttatgataca atggtggcaa
    27601 attttacttc tcactttgta ctcagcttat caaatctgtg atgagttgac gatcgtttca
    27661 tctgcaggtt cccctgtatt tgctggtttc attactggtt taatcatggg agatgtgact
    27721 actggtttac ttatcggtgg taacttgcaa ctgttcgttc ttggggttgg taccttcggt
    27781 ggtgcttctc gtatcgacgc aacttctggt gcggttcttg cgacagcctt ctctgtttca
    27841 caaggaattg atgcaccgct tgccattact acaatcgctg taccagtagc agctctcttg
    27901 acttacttcg acgttcttgg tcgtatgact actaccttct tcgctcaccg tgtggatgct
    27961 gcaatcgaac gctttgacta taaaggtatt gaacgcaact acttgcttgg tgcgattccg
    28021 tgggctctat ctcgtgccct tccagtcttc tttgcccttg cttttggtgg tgcctttgta
    28081 caatcagtag tagacttcgt tgaagcctac aaatgggttg cagatggctt gacacttgca
    28141 ggacgtatgc ttccaggtct tggatttgca atcttgcttc gttaccttcc agttaaacgt
    28201 aaccttcact accttgctat gggatttggt ttgacagcta tgttgactgt tctttactca
    28261 tatgtaacag gtcttggtgg cgctgttgct ggtatcgtag gtactcttcc tgctgaagtt
    28321 gctgaaaaaa ttggtttcgt gaacaacttc aaaggtttgt ctatgattgg tatttctatc
    28381 gtaggtattt tccttgcagt gcttcacttc aaaaatagcc aaaaagtagc tgtagcagca
    28441 ccttctacac catcagaaag tggggaaatc gaagatgacg aattctaatt acaaacttac
    28501 aaaagaagat tttaatcaaa tcaacaaacg tagcttgttt actttccaat taggttggaa
    28561 ctacgaacgt atgcaagctt ctggttacct ttacatgatc ttgcctcagt tgcgtaaaat
    28621 gtatggtgat ggaactcctg aattgaaaga aatgatgaaa gttcatactc aattcttcaa
    28681 tacttcacca ttcttccata ccattatcgc tggttttgac cttgccatgg aagaaaaaga
    28741 tggtgtaggt tcaaaagacg ccgttaacgg tatcaagaca ggtttgatgg gaccattcgc
    28801 tcctcttggg gatacaatct ttggttcact tgtacctgct atcatggggt cagtcgcagc
    28861 aactatggct atcgctggcc aaccttgggg gatcttcctt tggattgcag ttgcagtagc
    28921 gtatgacatc ttccgttgga aacagttgga atttgcttac aaagaagggg ttaaccttat
    28981 caacaacatg caaagtacct tgacagcttt gattgacgct gcatctgtac ttggtgtctt
    29041 catgatgggt gctcttgtag caacagtgat taactttgaa atttcttaca agttgccaat
    29101 cggtgaaaag atgattgatt tccaagacat cttgaaccaa atcttcccac gtttgcttcc
    29161 agcaatcttt actgccttta tcttctggtt gcttggtaag aaaggtatga actctactaa
    29221 agctatcggt attattatcg tacttgcttt ggctctttct gcccttggtc actttgcact
    29281 tggaatgtaa ttccttatga ctaaatcatt aattttggtg agccatggtc gcttctgtga
    29341 ggagcttaga ggtagtacag aaatgattat gggcccacaa gacaacattt acacagtagc
    29401 tcttcttcca gaagatggcc cagaagaatt tactgctaaa tttgaagctg ttattgaagg
    29461 attggatgat ttcctagtct ttgcggatct tctcggtggg acaccttgta atgtggtgag
    29521 tcgcttgatc atggaaggtc gtgatattga cctttacgca gggatgaatc ttccaatggt
    29581 gattgaattt atcaatgcga gccttacagg cgcagatgcg gactacaaga tccgtgctgc
    29641 agaaagcatt gtgaaagtta atgacctgtt agcgagcttc gatgatgacg aagatgaata
    29701 atactcttcg aaaaactctt caaactacgt caacgtcgcc ttgccgtagg tatatgttac
    29761 tgacttcgtc agtcttatcc ggcaacctca aaacggtgtt ttgagctgac ttcgtcagtt
    29821 ctatctgcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct attttagttg
    29881 gaactcgatt caattcatgt gacaacgtga aaatcgttag agcattttat atagaatata
    29941 catgggaatg tagcttactc tcattcccat atttaataga aaaagaggaa ctcaatgcta
    30001 cattatacaa aagaagactt gctcgaattg ggtgcagaaa tcactacgcg tgaaatctac
    30061 caacagcctg atgtatggag agaagctttt gaattttatc aagcaaaacg tgaagaaatt
    30121 gcagccttcc tacaagaaat cgctgataaa catgactata ttaaggttat cttgacaggt
    30181 gctgggactt ctgcttatgt gggagatacc ttgctacctt attttaagga agtctatgac
    30241 gaacgcaaat ggaatttcaa tgctattgcg acaacagata tcgttgccaa tccagcaacc
    30301 tatttgaaaa aagatgtggc aactgtcctt gtgtcttttg ctcgtagtgg gaactcgcct
    30361 gaaagtgtgg cgactgttga tttggccaaa tccttggtgg atgagcttta tcaagtgacg
    30421 attacttgtg cagcagatgg taaattggct cttcaagctc acggtgatga ccgtaatctc
    30481 ttgctcttgc aaccagctgt ctctaatgat gctggatttg ccatgacttc tagctttacg
    30541 tctatgatgt tgacagctct cttggtcttt gatcctacag aatttgctgt taagtctgaa
    30601 cgttttgaag ttgtatctag tcttgcccgt aaagttttag acaaggtaga agatgtcaaa
    30661 gagctcgttg atttagactt taaccgtgtc atctatctag gcgctggtcc tttctttgga
    30721 cttgctcatg aagctcagct caagattttg gaattaactg ctggtcaagt tgcgaccatg
    30781 tatgaaagcc cagttggctt ccgtcacggt ccaaaatctc ttatcaacga caatacagtt
    30841 gttttggtct ttggtacaac gacagcctac actcgtaagt acgacttgga cttggttcgt
    30901 gaagttgctg gtgaccagat tgctcgtcgt gttgtgcttt tgagtgatca agcttttggt
    30961 cttgaaaatg tcaaagaagt ggtccttggt tgtggcggtg tcttgaatga tatttaccgt
    31021 gtcttccctt acatcgttta tgcccaactc tttgctctat tgacttcact caaggtagaa
    31081 aataaaccag atacaccgtc tcctacaggt acagtaaacc gtgtagtaca aggtgtcata
    31141 attcacgaat atcaaaagta agacagtgtt tatgaattct tgacaagagg atttgtaaat
    31201 tatcagataa accatagatt gtcagtacgc tttctatggt ttgtttgctt gagagaaata
    31261 gtaaaaggag aacagaatga aagcatacac agagcgtgta tttggaaatg ttgagggcga
    31321 ggatgtcttg gcctatcgat ttgagacaga cggtggctac caacttgagg ttatgactta
    31381 tggtgcgacc atcttgcgct atgtcgcacc tgacaaggct ggaaattttg ccaatgttat
    31441 cttgggattt gatgactttg atagttatgt aggcaatagt cccaagcatg gagcaagtgt
    31501 aggtcctgta gcgggtcgta ttgcaggtgc gacctttgag ctcaatggta agacctatga
    31561 ccttgaggtt aataatgcta gcaactgtaa tcacagtggt tcaactggtt gggattccag
    31621 cttgtttgaa gttgaagaag taagcgatca tggcttgact ctctacacag agcgtacaga
    31681 tgggacagga gggttccctg gaaatctcaa gatttggatc agttatcact tggaagaaac
    31741 tggtgcctat gaaatcagct acaaggtaac gaccgatcag gatacgctgg tcaatccaac
    31801 caaccacagc tatttcaact tgtctggtga tttcacgcag acgattgacc gtcatgtctt
    31861 ccaactaaac acagagggca tttactcaat cgctcctgac ggtgttcctg ccaaaactcc
    31921 agaagccaac cgtgatgtgg tcaaacacat ctacaatggt gccttgttga aggatatctt
    31981 tgcagaagaa gatgagcaaa tccagctggc atcaggtttg gatcatccat ttgcccttcc
    32041 tgcaggccat gacaatgctg gattccttta tgaccaaaat tcaggtcgct tcctgctttt
    32101 caagacagaa gctccttgct ttgtggtcta cacagcaaac tttgtggatg aaagtgtcat
    32161 cataggaggt cagccaatgc tacagcacaa tgggattgct cttgaagcgc aagctttacc
    32221 agatgccatt cacagtgacc ttaaaggcca agtcattctt aaagctggtc aaaccttcac
    32281 cagtaagaca cgttatgaac ttgttgtgaa ataaaaaagc tggtcaaaaa gtctttaaaa
    32341 ttaaaataac gcatattgtc aggtgatgaa aagtttgata atatgcgttt tattatgaaa
    32401 tgatttactt tatattatcc tgaaatggtg ttatttttga gttatctggc ttgactttct
    32461 tgatggaaat tatataatag ttgtaacaat aataattaca acgagaaaag aggaccattt
    32521 atgacctatg aatacaagag tcacatttat ttggcagaga cagttttaaa tgtaaaggat
    32581 ttggccagtc aaacagcctt ttatcagcaa gttatcggtt tagaaatctt atctcaaact
    32641 gagacagagt ccattctagg cattggtgga aaagtcttgg tacagctgat tcaagcacaa
    32701 gagagcggag aagtgaggga acattatggt ctttaccatt tggccattct cttgcccaca
    32761 cgcaaggctt tggctgatgt cttgaaacac ctgacagatt tacagattcc tcttgtcggc
    32821 ggtgcagacc atggttacag tgaagctatt tacttggaag atttggaggg aaatggcatt
    32881 gaactctatc gagataagcc agtttccaca tgggatattc gagaagatgg acgcattatc
    32941 ggagtgacgg aggctcttgc ggcgcaggac atttatgagt tgggggaaag agtagagccc
    33001 tttatcctgg cagaaggtac gagaatgggg catattcatc tttccgtcaa ggatagtcga
    33061 aagtccagcc agttttatca aaaggtgtta gggctagaga ataaattcag tgtgcctggc
    33121 gctagttgga ttgcggctgg agattaccat catcatttag cagttaacga atggagagga
    33181 aaaggtctgg cttcgcgtaa gcaaggctta ccaggtttag cctactatgt catcgaagtc
    33241 gcacataaaa aagaactgtt aacgattgcc caacgagcac aagaagttga cgcaccaatc
    33301 aaatggatga catcgagcaa attggaaatc acagactcag atggcatcgt gacccgtatt
    33361 cgtttagcaa ggtaaaatta ggaattttta ataagttata agtattgcta gtttgctttt
    33421 tgaacggtct ttggtaacag aactgcgtga gctggatggg tgagaatttt gacaaagaag
    33481 ctgattagag atataatgaa gaaaaatcga gcaaggaaaa agaaatgaca aattcaaagt
    33541 atattactcg tttgaaacgt tcagagggcc agttgcgtgg gattcaaaag atgattgaag
    33601 gagatcgtga ctgtgctgat attgtgacgc aactgacagc agtgaaatct agtgtagagc
    33661 gcgtgattga gatgataatt accgaaaatc ttactgaatg tatcaatcag cccctagatg
    33721 attctgaagc tcaaaaggaa cgcctagaga aggctatctg atacttgatt aaacggaaat
    33781 aaatgaatgt tttgagacga tatgtgcaaa ggtctattaa ctattagaat agtttaatgt
    33841 aagtcaaaag aagttgtaaa aaatctttaa aattaaaaaa cgcatagtat caggtattga
    33901 aatgtactgc cccccaaaag ttagattttt tctgtctaac ttttgggggg cagtacataa
    33961 aaaccttgat agtatgcgtt ttattgtggg gagacttata ctcttcgaaa atctcttcaa
    34021 accacgtcag tttcaccttg ccgtagatat ggttactgac ttcgtcagtt ctatccacaa
    34081 cctcaaaaca gtgttttgag ctgacttcgt cagttccatc cacaacctta aaacagtgtt
    34141 ttgagcagcc tgcggctaac ttcctagttt gcactttaat tttcattgag tattacttca
    34201 tcttctcatg aaattgagtt tttgcccagc tcctcttgat tattctactt gaccgggcca
    34261 agtattcata ccaccttcta cgttggtaac ggtgaggcct tgggagctga gaaattggca
    34321 ggtagatgca gagcggactc ctccttgaca aataacatag tattcatggt caggtttgag
    34381 ttctttgtag ccttgctcta aggtacttaa tggaagattt ttggcacctg gtgcatgtcc
    34441 tgcttggaat tcatgtgctt cacggacatc gataagttct agattttcat tttggtattt
    34501 tccataaaag tcagccatgc tgatactagt ttccatattc tactccttct gggttagcca
    34561 ttttgtatag tgaataagcg ccgtcaaggt tttggacggt aaatcctgct tgcttgagga
    34621 taggctctgc gatatagctg cgcaaaccac tgtggcagct gacgatgtag gcttgttttt
    34681 tgtccagttc atcagcttcc tccttgacac tttgtcagtt tttgatacaa tagtacaaaa
    34741 ttagaggagg tgggctatga ttcagaaaca tgcgattccc attttagagt ttgatgataa
    34801 tcctcaggcg gttatcatgc ccaatcacga ggggttggat ttgcagttgc caaagaagtg
    34861 tgtctatgct tttttaggtg aggagattga ccgctatgcg agggaagtag gggcgaactg
    34921 tgttggcgaa ttcgtttctg ctaccaagac ctatccagtc tatgtcatca actacaaggg
    34981 tgaggaggtc tgtctggctc aggctcctgt tggctccgct ccagcagccc agtttatgga
    35041 ttggttgatt ggctatggtg tggagcagat tatctctact gggacctgtg gtgtcctagc
    35101 tgatatagag gaaaatgcct ttctagtccc tgttcgcgct ttgcgagatg agggagccag
    35161 ttaccactat gtggcacctt gtcgttatat ggaaatgcag ccagaggcta ttgctgctat
    35221 tgaggaagtt ttggaagaca gagggattcc ttatgaagaa gtcatgacct ggacgacaga
    35281 cggtttttac cgagaaacgg ctgaaaaggt ggcttatcgt aaggaagaag gctgtgctgt
    35341 tgtggagatg gagtgttctg ctcttgcggc agtagctcaa ttgcgtgggg ttctctgggg
    35401 tgaattgttg ttcacagcag attctctagc ggacttggac cagtacgaca gtcgtgactg
    35461 gggctcggaa gcttttaata aggcgctaga actgagttta gcaagtgttc accaccttta
    35521 gttgtactgg caaaggattt gttttatcat aaaatgtcta gctcatactt ttcaaaaata
    35581 tgtttaaacg aggtcacctt cctcttgtcc taggcatgtt gaggttggga aaaatcttta
    35641 aaatcagaaa aacgtatcat atcaggtgat gaaaactttg atactatgcg ttttatgttg
    35701 gtaagattta gagtgagatg aaatgatact cttcgaaaat ctcttcaaac caggtcagct
    35761 tcaccttgcc gtaggtatat gttactgact tcgtcagtct tatccggcaa cctcaaaacg
    35821 gtgttttgag ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc
    35881 tgtgactagc tttctaagcg atgccttggt tctcattgcc tataatcaaa aagagaaatt
    35941 ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc ttttttgacc
    36001 tatagtcaca tctatcaagt attgttcttg cctaagctat caataaaaag gtggcatttt
    36061 ttaggcttgg tgttagtaga ttttgcctta tcctatctaa gtcatttcga gctttttatg
    36121 gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag gcttatctcg
    36181 tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac taggctctct
    36241 tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt ttgatcatct
    36301 tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag tagctcacac
    36361 ctataatata tggggccaaa taatctgttt gctcttgatt cagatcggtg gtctagggct
    36421 catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc ttcgtagccg
    36481 tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa agtttgtcta
    36541 ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc ttagttttcg
    36601 ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc tagcgatctc
    36661 agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg cttttcagac
    36721 cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc ttggttttat
    36781 ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca
    36841 tacgaagctt gtattattat taactatagg tttgttgtta tttggaacgg caactactct
    36901 ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg ataaggtttt
    36961 agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga tagattatac
    37021 tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag gtggggcacc
    37081 tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg tctttgcacg
    37141 aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgatcg cgccgcgaac
    37201 ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga taggattgat
    37261 tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcgtat ttgaaaccat
    37321 ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg ggaaattggc
    37381 tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga ccttgtttgt
    37441 tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga aagcagatat
    37501 tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt ttgggcttgg
    37561 gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat attatcgcta
    37621 ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt ggagtgattg
    37681 gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc gataccgttg
    37741 tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt
    37801 tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa
    37861 agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct ctagcacaga
    37921 ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg
    37981 agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac ctccgtggca
    38041 aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg gatgttgaat
    38101 ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc aacaaccagt
    38161 atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt ttttgatgcc
    38221 caagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt caaaggctgg
    38281 actttatggt aaaatagaaa gaagtgacaa gagagagtaa tactcaatga aaatcaaaga
    38341 tcaaactagg aaactagcta cgggctgctc aaaacagtgt tttgaggttg cagatagaac
    38401 tgacgaagtc agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc
    38461 gaagagtata agaaaaaatc agccccctaa aggagcagat tatgaagtta ttgtctatcg
    38521 ccatttctag ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg
    38581 gtggtgagca agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa
    38641 tcgctgagtg tttagctagc aagtatccta atatcgttag agccatctat caggaaaata
    38701 aaggccatgg cggtgtggtc aatcgcggct tggcagaggc ttctgggcgc tattttaaag
    38761 tagttgacag tgatgactgg tggatcctcg tgcctacttg aaaattcttg aaaccttgca
    38821 ggaacttgag agcaagggtc aagagatgga tgtctttgtg accaattttg tctatgaaaa
    38881 ggaaggtcag tcttgtaaga agagtatgag ttacgattca gtcttgcctg ttcggcagat
    38941 ttttggctgg gaccaggtcg gaaatttctc caaaggccag tatatcatga tgcactcgct
    39001 gatttatcgg acagatttgt tgcgtgctag ccagttctaa ttgcctgaac atacttttta
    39061 tgtcgataat ctctttgtct ttacgcccct tcagcaggtc aagaccaggt actatctgcc
    39121 tgtcgatttc tatcgttatt tgattaggcg tgaggaccag tctgtcaatg agcaagtgat
    39181 gattaagtgc attgaccagc aactcaaggt caatcgactc ttggtagacc agcttgattt
    39241 gtcccaagtg agtcatccta aaatgcgaga atatctgctg aatcatattg aaatcacgac
    39301 ggtgatttcc agtaccctgc tcaaccgatc tgaaacagcg gagcatctgg caaaaaaacg
    39361 ccaattgtgg acctatattc agcaggaaaa tccaaaagtc tttcaggcta ttcgtaagac
    39421 catgttgagc cgtttgacca aacattctgt cttgccagat cgcaaactgt ccaatgtcgt
    39481 ctatcaaatc accaaatctg tttatggatt taattaatat aagtgtttta taagagggat
    39541 ttaagaaaaa ttttaacttt ttcttagtcc tttttaattt caggagatta tactagagtc
    39601 atcaaataaa gaaagactct aaggagaatc ctatgaaatt caatccaaat caaagatata
    39661 ctcgttggtc tattcgccgt ctcagtgtcg gtgttgcctc agttgttgtg gctagtggct
    39721 tctttgtcct agttggtcag ccaagttctg tacgtgccga tgtggtcaat ccgaccccag
    39781 gtcaagtctt acctgaagag acatcgggaa cgaaagaggg tgacttatca gaaaaaccag
    39841 gagacaccgt tctcactcaa gcgaaacctg agggcgttac tggaaatacg aattcacttc
    39901 cgacacctac agaaagaact gaagtgagcg aggaaacaaa ctcttctaga ctggatacac
    39961 tttttgaaaa agatgaagaa gctcaaaaaa atccagagct aacagatgtc ttaaaagaaa
    40021 ctgtagatac agctgatgtg gatgggacac aagcaagtcc agcagaaact actcctgaac
    40081 aagtaaaagg tggagtgaaa gaaaatacaa aagacagcat cgatgttcct gctgcttatc
    40141 ttgaaaaagc tgaagggaaa ggtcctttca ctgccggtgt aaaccaagta attccttatg
    40201 aactattcgc tggtgatggt atgttaactc gtctattact aaaagcttcg gataatgctc
    40261 cttggtctga caatggtact gctaaaaatc ctgctttacc tcctcttgaa ggattaacaa
    40321 aagggaaata cttctatgaa gtagacttaa atggcaatac tgttggtaaa caaggtcaag
    40381 ctttaattga tcaacttcgc gctaatggta ctcaaactta taaagctact gttaaagttt
    40441 acggaaataa agacggtaaa gctgacttga ctaatctagt tgctactaaa aatgtagaca
    40501 tcaacatcaa tggattagtt gctaaagaaa cagttcaaaa agccgttgca gacaacgtta
    40561 a
//
LOCUS       DAVLTG010000013        40207 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLTG010000013 DAVLTG010000000
VERSION     DAVLTG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.013"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            5..75
                     /locus_tag="VYN12_000725"
     tRNA            5..75
                     /locus_tag="VYN12_000725"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VYN12_000726"
     tRNA            110..183
                     /locus_tag="VYN12_000726"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VYN12_000727"
     tRNA            266..355
                     /locus_tag="VYN12_000727"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VYN12_000728"
     tRNA            366..439
                     /locus_tag="VYN12_000728"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VYN12_000729"
     tRNA            443..515
                     /locus_tag="VYN12_000729"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VYN12_000730"
     tRNA            528..608
                     /locus_tag="VYN12_000730"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VYN12_000731"
     tRNA            613..683
                     /locus_tag="VYN12_000731"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VYN12_000732"
     tRNA            698..770
                     /locus_tag="VYN12_000732"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            784..855
                     /locus_tag="VYN12_000733"
     tRNA            784..855
                     /locus_tag="VYN12_000733"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:816..818,aa:Gln,seq:ttg)
     gene            865..948
                     /locus_tag="VYN12_000734"
     tRNA            865..948
                     /locus_tag="VYN12_000734"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:899..901,aa:Leu,seq:caa)
     gene            1055..2332
                     /locus_tag="VYN12_000735"
     CDS             1055..2332
                     /locus_tag="VYN12_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1415152.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2408..3892
                     /locus_tag="VYN12_000736"
     CDS             2408..3892
                     /locus_tag="VYN12_000736"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1415153.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3953..5233
                     /locus_tag="VYN12_000737"
     CDS             3953..5233
                     /locus_tag="VYN12_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1415154.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5237..5857
                     /locus_tag="VYN12_000738"
     CDS             5237..5857
                     /locus_tag="VYN12_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1415155.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6023..7135
                     /locus_tag="VYN12_000739"
     CDS             6023..7135
                     /locus_tag="VYN12_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1415156.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7458..7883
                     /locus_tag="VYN12_000740"
     CDS             7458..7883
                     /locus_tag="VYN12_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1415157.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7894..8253
                     /locus_tag="VYN12_000741"
     CDS             7894..8253
                     /locus_tag="VYN12_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1415158.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8360..9004
                     /gene="pcp"
                     /locus_tag="VYN12_000742"
     CDS             8360..9004
                     /gene="pcp"
                     /locus_tag="VYN12_000742"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1415159.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(9032..9889)
                     /locus_tag="VYN12_000743"
     CDS             complement(9032..9889)
                     /locus_tag="VYN12_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1415160.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10019..11161
                     /gene="tgt"
                     /locus_tag="VYN12_000744"
     CDS             10019..11161
                     /gene="tgt"
                     /locus_tag="VYN12_000744"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1415161.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11259..13076
                     /locus_tag="VYN12_000745"
     CDS             11259..13076
                     /locus_tag="VYN12_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1415162.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13229..14380
                     /gene="nagA"
                     /locus_tag="VYN12_000746"
     CDS             13229..14380
                     /gene="nagA"
                     /locus_tag="VYN12_000746"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1415163.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14543..15601
                     /locus_tag="VYN12_000747"
     CDS             14543..15601
                     /locus_tag="VYN12_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1415164.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15752..16117
                     /locus_tag="VYN12_000748"
     CDS             15752..16117
                     /locus_tag="VYN12_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1415165.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16192..17133
                     /locus_tag="VYN12_000749"
     CDS             16192..17133
                     /locus_tag="VYN12_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1415166.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17081..18097
                     /locus_tag="VYN12_000750"
     CDS             17081..18097
                     /locus_tag="VYN12_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1415167.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18099..18425
                     /locus_tag="VYN12_000751"
     CDS             18099..18425
                     /locus_tag="VYN12_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV1415168.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            18418..18822
                     /locus_tag="VYN12_000752"
     CDS             18418..18822
                     /locus_tag="VYN12_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1415169.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18827..19087
                     /locus_tag="VYN12_000753"
     CDS             18827..19087
                     /locus_tag="VYN12_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415170.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19050..19511
                     /locus_tag="VYN12_000754"
     CDS             19050..19511
                     /locus_tag="VYN12_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1415171.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19489..19935
                     /locus_tag="VYN12_000755"
     CDS             19489..19935
                     /locus_tag="VYN12_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1415172.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            20038..20625
                     /locus_tag="VYN12_000756"
     CDS             20038..20625
                     /locus_tag="VYN12_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1415173.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20686..21639
                     /locus_tag="VYN12_000757"
     CDS             20686..21639
                     /locus_tag="VYN12_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1415174.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21690..22880
                     /locus_tag="VYN12_000758"
     CDS             21690..22880
                     /locus_tag="VYN12_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1415175.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23029..23400
                     /gene="rnpA"
                     /locus_tag="VYN12_000759"
     CDS             23029..23400
                     /gene="rnpA"
                     /locus_tag="VYN12_000759"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1415176.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVN"
     gene            23375..24199
                     /locus_tag="VYN12_000760"
     CDS             23375..24199
                     /locus_tag="VYN12_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1415177.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24218..25204
                     /locus_tag="VYN12_000761"
     CDS             24218..25204
                     /locus_tag="VYN12_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1415178.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25255..25878
                     /locus_tag="VYN12_000762"
     CDS             25255..25878
                     /locus_tag="VYN12_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1415179.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26009..27466
                     /locus_tag="VYN12_000763"
     CDS             26009..27466
                     /locus_tag="VYN12_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1415180.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLAAYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27489..27770
                     /locus_tag="VYN12_000764"
     CDS             27489..27770
                     /locus_tag="VYN12_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1415181.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQRDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27846..28331
                     /locus_tag="VYN12_000765"
     CDS             27846..28331
                     /locus_tag="VYN12_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1415182.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28348..29013
                     /locus_tag="VYN12_000766"
     CDS             28348..29013
                     /locus_tag="VYN12_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1415183.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29017..29880
                     /locus_tag="VYN12_000767"
     CDS             29017..29880
                     /locus_tag="VYN12_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1415184.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29882..30586
                     /locus_tag="VYN12_000768"
     CDS             29882..30586
                     /locus_tag="VYN12_000768"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1415185.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYRAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30765..32438
                     /locus_tag="VYN12_000769"
     CDS             30765..32438
                     /locus_tag="VYN12_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1415186.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEQEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32550..33641
                     /gene="ulaG"
                     /locus_tag="VYN12_000770"
     CDS             32550..33641
                     /gene="ulaG"
                     /locus_tag="VYN12_000770"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1415187.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33755..35731
                     /gene="tkt"
                     /locus_tag="VYN12_000771"
     CDS             33755..35731
                     /gene="tkt"
                     /locus_tag="VYN12_000771"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1415188.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35848..36147
                     /gene="yajC"
                     /locus_tag="VYN12_000772"
     CDS             35848..36147
                     /gene="yajC"
                     /locus_tag="VYN12_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1415189.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36193..36621
                     /locus_tag="VYN12_000773"
     CDS             36193..36621
                     /locus_tag="VYN12_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1415190.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36623..37033
                     /locus_tag="VYN12_000774"
     CDS             36623..37033
                     /locus_tag="VYN12_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415191.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILTVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37333..39984
                     /gene="adhE"
                     /locus_tag="VYN12_000775"
                     /gene_synonym="adhC"
     CDS             37333..39984
                     /gene="adhE"
                     /locus_tag="VYN12_000775"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1415192.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12200 a         7213 c         9070 g        11724 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tattggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga
      841 atccagctac cccagttact atttgccggc gtggcggaat tggcagacgc gctggactca
      901 aaatccagtg tccgcaagga cgtgccggtt cgaccccggc cgccggtata gtatagtgtt
      961 aggaacgttg ttattcttcg ttcctttttt atattatttt tggtataatt atagttattc
     1021 aaattttatt tagattaaga aagtgtaggg gagtatgtct tgttctatcg atttattaaa
     1081 acatcggtat ttgaaaaata ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga
     1141 gtatcctgtt gcaagtttag aaggggatgc tacagatgtt gaagttatga aggatctatt
     1201 tcattattta gtttctactt tggatctcac cgtagcaaag gtagatgatt ttggcaatct
     1261 gatccagtta gtagatccga taagtcagga tgctatttta tttgaagttt cctatacaac
     1321 gattgagttt gcatttggta aggctgaaac gattcaagag gtcgaaaatc gtttcaataa
     1381 ttatatgaat gtaattcaga gaaagttagc tgaatcaaat catgctattg ttggctgtgg
     1441 tatccatccc aactgggata aaaatgagaa ttgtccagtg gcttatccac gctatcagat
     1501 gttgatggat tatttgaatt tgagtagaaa tattattaaa tcagatttac atcatttccc
     1561 tgaatatggt acttttatct gtgggagcca ggttcagctg gatatttcaa aaaccaacta
     1621 cttacgggtg attaatgctt ttactcaaat tgaagcggct aaggcttatt tatttgcaaa
     1681 ctctgaattt tcgggtgcgg attgggatac gaaaatttca agggatattt tctgggaaga
     1741 atctatgcat ggtatctatc cagagaatgt tggggtcaat gctagactcc ttaatgatga
     1801 agctgatttt tttgactatc taaatcattc tgcgattttt actgcggaac gtgatgggca
     1861 gacctattat ttttatccta ttcaggctgg ggactatttg gctacgtccg aaatccaagc
     1921 atttgctctg aatggggatg aggttattat ttacccccaa gagaaggatt ttgaaactca
     1981 tcgtagttac cagtaccaag atttaacgac tcgaggaaca gttgagtttc gtagtgtgtg
     2041 tacacagcca cttgatagga cttttgcttc tgcagctttt cacttgggat tattggttaa
     2101 tttagacaag ttagaagctt acttagaaac agcacctttc tttaaagtat ttggttatga
     2161 ttacaagtct ttaaggagac aattttctaa gaaaaatctt acagatgagg aagaaactac
     2221 gattattgaa ttttccaaag acttactcct actagctgag gagggactag tggtgagaaa
     2281 taaggaagaa atgacctatt tacagccttt gagagaagaa ttgagcctat aatttctctt
     2341 ataaagggag aattttctga aaaatcatga tataatggac gagactatag ataaaggata
     2401 gagagtaatg acattagttt atcaatcaac gcgtgatgcc aacaatacag taactgccag
     2461 ccaagcaatt ttgcaaggtt tggcgacgga cggcggtttg tttacaccgg atacttatcc
     2521 aaaggtagat ttgaactttg acaaattgaa agatgcttct taccaggaag ttgctaagct
     2581 agttttgtca gcatttttag atgactttac agttgaggag ttggactact gtatcaacaa
     2641 tgcctacgat agcaaatttg atactccagc tattgcacca ttagtgaaat tagatgggca
     2701 atacaatttg gaacttttcc atggttcaac gattgccttt aaggatatgg ccttgtctat
     2761 tttgccatac tttatgacga ctgctgctaa gaaacatggt ttggagaaca agattgttat
     2821 cttgacagcg acatctggtg acacggggaa agctgctatg gcggggtttg cgaatgtgcc
     2881 tggtactgag attatcgtct tttatccaaa ggatggtgtc agcaagattc aagagttaca
     2941 aatgaccact cagactggcg acaatactca tgttattgct attgatggta actttgacga
     3001 tgcgcaaaca aatgtgaagc acatgtttaa cgacgtggct cttcgtgaaa aattgactac
     3061 caacaagttg caattttcat cagctaactc tatgaacatt ggtcgtctgg tgccacaaat
     3121 tgtttattat gtttatgctt acgctcaatt ggttaagact ggtgaaattg tagctggtga
     3181 aaaggttaac ttcacagtac caacaggaaa ctttggaaat atcttggctg ccttttatgc
     3241 caaacaaatt ggtttgccag ttggtaaatt aatctgtgct tcaaatgaca acaatgtttt
     3301 gacagacttc tttaaaacac gtgtctatga caaaaaacgt gagtttaagg taacaaccag
     3361 cccatctatg gatatcttgg tatcttcaaa cttggagcgc ttgattttcc atcttttggg
     3421 aaataatgct gaaaagacaa ctgaacttat gaatgccttg aacacgcaag gacaatataa
     3481 gttgacagac tttgatgcag agattttgga cctctttgca gctgaatatg cgactgagga
     3541 agaaacggca gcagagatca agcgtgtttg tgagttagat tcttatatcg aggaccctca
     3601 tacagctgtt gcttcagcag tttataaaaa ataccaatcg gccactggag atgtaactaa
     3661 gacagtgatt gcttcaacag ctagtccata caagttccca gtagttgcag tagaagctgt
     3721 aactggaaaa gcaggtttaa cagactttga agccttggct caattacatg aaatctcagg
     3781 cgttgcagtg ccaccagcag ttgatgggct tgaaatagct ccaattcgtc acaagacaac
     3841 agtggcagct gctgacatgc aagcagcggt tgaggcttat ttaggacttt aagacagagg
     3901 gagcaaactc ggttgggaaa ccaactgagt ttcttttcat caggaggaga gattgtttaa
     3961 gaaaaataaa gacattctta atattgcatt gccagctatg ggtgaaaact ttttgcagat
     4021 gctaatggga atggtggaca gttatttggt tgctcattta ggattgatag ctatttcagg
     4081 ggtttcagta gctggtaata ttatcaccat ttatcaggcg attttcatcg ctctgggagc
     4141 tgctatttcc agtgttattt caaaaagcat agggcagaaa gaccagtcga agttggccta
     4201 tcatgtgact gaggcgttga agattacctt actattaagt ttccttttag gatttttgtc
     4261 catcttcgct gggaaagaga tgataggact tttggggacg gagagggatg tagctgagag
     4321 tggtggactg tatctatctt tggtaggcgg atcgattgtt ctcttaggtt taatgactag
     4381 tctaggagcc ttgattcgtg caacgcataa tccacgtctg cctctctatg ttagtttttt
     4441 atccaatgcc ttgaatattc ttttttcaag tctagctatt tttgttctgg atatggggat
     4501 agctggtgtt gcttggggga caattgtgtc tcgtttggtt ggtcttgtga ttttgtggtc
     4561 acaattaaaa ctgccttatg ggaagccaac ttttggttta gataaggaac tgttgacctt
     4621 ggctttacca gcagctggag agcgacttat gatgagggct ggagatgtag tgatcattgc
     4681 cttggtcgtt tcttttggga cggaggcagt tgctgggaat gcaatcggag aagtcttgac
     4741 ccagtttaac tatatgcctg cctttggcgt cgctacggca acggtcatgc tgttggcccg
     4801 agcagttgga gaggatgatt ggaaaagagt tgctagtttg agtaaacaaa ccttttggct
     4861 ttctctgttc ctcatgttgc ccctgtcctt tagtatatat gtcttgggtg taccattaac
     4921 tcatctctat acgactgatt ctctagcggt ggaggctagt gttctagtga cactgttttc
     4981 actacttggg acccctatga cgacaggaac agtcatctat acggcagtct ggcagggatt
     5041 aggaaatgca cgcctccctt tttatgcgac aagtatagga atgtggtgta tccgcattgg
     5101 gacaggatat ctgatgggga ttgtgcttgg ttggggcttg cctggtattt gggcagggtc
     5161 tctcttggat aatggttttc gctggttatt tctacgctat cgttaccagc gctatatgag
     5221 cttgaaagga taggaaatgc aaaaaacagc ttttatttgg gatttagacg ggactttatt
     5281 ggactcttac gaagcgattt tatcagggat tgaggagact tttgctcagt tttctattcc
     5341 ttatgataag gagaaggtga gagagtttat cttcaagtat tcggtgcaag atttgcttgt
     5401 gcgggtggca gaagatagaa atctggatgt tgaggtgcta aatcaggtgc gtgcccagag
     5461 tctggctgag aagaatgctc aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg
     5521 ggcagacgaa tcaggaattc agcagtttat atatactcat aaggggaaca acgcttttac
     5581 cattctcaag gacttggggg tggaatccta ttttacagag attttaacca gtcagagtgg
     5641 ctttgtgcgg aagccaagtc cagaagcggc tacctatctg ctagataagt atcagttgaa
     5701 ttctgataat acttattata taggggatcg gactctggat gtggaatttg cccagaatag
     5761 tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca ggattcaagc
     5821 gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg tcagttttgt
     5881 gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat agacagttct
     5941 gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata gacaggtact
     6001 catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt
     6061 gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg cacgtagtgt
     6121 tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata ccgtacagta
     6181 tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtaacag tgcttgcgaa
     6241 tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga caacgactgt
     6301 caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag actctagtga
     6361 agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg atgatcaaac
     6421 tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag tgattgcttc
     6481 tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga ccgaaacaac
     6541 tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc aggaaacaca
     6601 agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag aagcaaaaga
     6661 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
     6721 aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac ttgcagtagc
     6781 aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
     6841 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
     6901 aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata agattgcgga
     6961 atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
     7021 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
     7081 tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg gataaacccg
     7141 acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag cgattctcgt
     7201 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt tttatctgaa
     7261 acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
     7321 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
     7381 ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga taaatcaata
     7441 aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc cgcttgtctg
     7501 agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca cggtatcaga
     7561 ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag gagcgtttga
     7621 aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa ggtttggtgg
     7681 agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg aagtatgcca
     7741 aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa gagatagaaa
     7801 gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa ttggttttgg
     7861 gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac aacgatcgtt
     7921 gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc agatgcgact
     7981 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     8041 aaaaatcaag gaatttataa ggctctgcta ggagtctttc tcttgtatgt catttatttc
     8101 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     8161 ggctctttaa cagcggataa aaaaattatt ttgaaacaag gtggatcagc tattttggcc
     8221 ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc gctaatcctt
     8281 tttaatccag aataagggaa atatgttata cttgttttta agaaaaaagt ctcattgaat
     8341 tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct ttggagggga
     8401 aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8461 ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8521 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8581 tttgacacct gaacgagtga ccattaatca agacgatgca tgcatttctg ataacgaaga
     8641 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8701 gccgattaaa gcgatggttc aagctataaa aaaagagggc ttaccggcct ctgtttccaa
     8761 tacggcaggg acttttgtct gcagccattt gatgtatcag gctctctatt tggtagaaaa
     8821 gaaatctcca tatgttaagg caggttttat gcatattcct tatatgatgg aacaggtggt
     8881 gaacagaccg actactccag ctatgagttt agtggatatt cggcgaggga tagaagcagc
     8941 aatcggcgct ataatagaac atggagatca ggaactcaag ttggtaggcg gagaaactca
     9001 ttgatagaaa aaagcttgag gggaaaaacc ttcaagcttt tggacgtttt cgggccaata
     9061 ctgctcggta aaacataatt ttagtgcatt ggatataagg taggagtgaa aaactagcaa
     9121 tgccaaaggt aatccaattg aggaagtacc aaggaagaag ctgtaaatct aggacaaagt
     9181 gctggaactt gtagcccttc ataaaggaac ggctagtttt taggattcgt cttggtggga
     9241 cctgtcctag gtctagacta taacagagaa gaaattccac ctgtgaatag gcataatact
     9301 gtggaatata gaggatattt cctacaatga tcaagatgag acttgcaaga aagtagagtc
     9361 caaagaccat gaggaaacgc tcggtttcaa ctgatgagag atctagattt ggaaactcag
     9421 gatgtagggt gacgaatttt ttggctaaaa agctactata aaagaggagg taaatcccaa
     9481 gtaaattagg gatactccat aaaaagagat agaaacgttt gagaagtagg gtcaaaaagg
     9541 tttgagaaaa gcgctcctca tcaaagagag ctaggctgtt ttttacagat ggctccgttt
     9601 tagaatcttt catgagtgtc agtgttgcat agacggaact ggtcaaaaga atagtcccga
     9661 taaaggagac tagtagagga aagaggtagg tttgaagtat ttggccaagt atgctgaaaa
     9721 atggctgttc taaaacagtc ccgtggatcc gagataaggg attaagaaaa ccagataaga
     9781 tgaccagcat actgggaagg atatagagga gaaagagacg gggggtgtca gcctgaaaat
     9841 gttttgactc ctgacgaatt gtttttaaat caatttttgg atagttcatt ctcttattat
     9901 accatagttc ttatacatag ttcgtgacag ttcctacttt ttttgataaa atcatacagt
     9961 gtgtccttgg gcacactgta tgaactggga ctgtctttcc cagcttcgga ggtaaaaaat
    10021 gtcagattca ccaatcaaat atcgtttgat taagaaagaa aaacacacag gagctcgtct
    10081 gggagaaatc atcactcccc acggtacctt tccgacacct atgtttatgc cagttgggac
    10141 acaagccact gtcaaaactc agtcacctga agaattgaag gagatgggtt cgggaattat
    10201 cctatcaaac acctatcatc tctggcttcg ccctggagat gaactcattg cacgcgctgg
    10261 tggtctccac aagttcatga attgggacca gcctatcttg acagatagtg gtggttttca
    10321 ggtttattct ttagcagata gccgtaatat cacagaagaa ggagtaacct ttaaaaatca
    10381 tctaaatggt tctaagatgt tcctatcccc agaaaaagcc atctctattc agaataatct
    10441 gggttcagac atcatgatgt cctttgatga atgtcctcag ttttatcaac cttatgacta
    10501 cgttaagaaa tcgatcgagc gtaccagccg ttgggctgag cgtggtttga aggctcaccg
    10561 tcgtccacat gaccaaggtt tgtttggaat tgtgcaaggt gcaggatttg aagaccttcg
    10621 ccgccaatca gctcatgatc ttgtcagcat ggatttctca ggctactcta tcggtggttt
    10681 ggcagtggga gaaacccatg aagagatgaa tgcggtcttg gactttacaa ctcaactgct
    10741 acctgaaaat aaacctcgtt atctgatggg tgtgggagcg ccagatagct tgatcgatgg
    10801 ggtcattcgt ggggtggata tgtttgactg tgtcttaccg actcgaattg ctcgtaacgg
    10861 gacttgtatg accagtcaag gacgtttggt tgtgaaaaat gcccagtttg ctgaggactt
    10921 tacgccactg gatcctgagt gtgactgcta cacatgtaat aactatacac gcgcttacct
    10981 tcgtcacctg ctcaaggctg atgaaacctt tggtatccgc ttgactagct accacaatct
    11041 ttacttcttg cttaacctga tgaagcaagt gcgacaagcc atcatggatg acaatctctt
    11101 ggaattccgt gagtattttg tggaaaaata tggctataat aagtcaggac gtaatttcta
    11161 aaatggaatt gatataaaaa aatcctaagt tttctcttag gatttttctt ctttttttga
    11221 tagaataaag tgtacaatga aaggaagaat aaactcgtat gcgcattaaa tggttttcct
    11281 tgattaggat tataggttta cttttggtac tcttgtatca cttctttcag acgatctttc
    11341 ctggaggatt tttcggggta gatgtctttt tcacattttc aggtttcctg attacagctc
    11401 tactcattga agaattttct aagaacaatg agattgattt gataggattt tttagaagac
    11461 gcttttatcg gattgtgcca cctgtggttt tgatggtctt ggtgaccatg ccttttactt
    11521 tcttggttcg ccaagactat gttgctggaa ttggtggcca gattgcgggc gtcttaggct
    11581 ttatgaccaa cttctatgaa ctcctaacag gtgggagtta tgaatctcag ttcattcctc
    11641 atttgtttgt tcataattgg agtttggcag ttgaggttca ctactatatt ctttggggat
    11701 tggcagtttg gttcttatcc aaacaagcta aatcaaatgg tcagttgaag gggatggtct
    11761 ttctcttatc tgctgctgcc ttcttgatca gtttcttctc catgtttatt ggtagttttc
    11821 tagtgacctc ttattcctct gtttatttct ccagtttaac tcatgtctat ccattctttt
    11881 tgggaagtat gttagcaact attgtaggtg ttcgtcagac gacttccctc gtcaagcagt
    11941 tggataaaat ctgggattta cgaaagactt tggtagtttt tggaggaggc tttggtttcc
    12001 tagttctttt gactttcttt gtcaaattca cttatctttt tgcctatctt atcggcttct
    12061 tgcttgccag tcttgcagct cttgccatga ttctggcggc gcgtgtctta catgaaaaga
    12121 cacatcatat acaggagccg aagattatca gctttttagc ggatactagc tatgcggttt
    12181 atcttttcca ttggcctttc tatatcattt tctcacagtt gacatcaaat cttcttgctg
    12241 tattactgac tctgatttgt tcttatggct ttgccagtct gtcattctat gtattggaac
    12301 cttggattgc aggcaagaac acacctattt tacaaactct tcgtcccctg ccttatattc
    12361 acgcaattct tgtagcaggt acaggaatct tgaccatcat tgtctgcacg gtgaccttgt
    12421 tggcaccaca agtgggagcg tttgagacag acttgactgt caatggcttg aagcaagctg
    12481 caacaaatat tggccagacc aaggtgatgg cagaacgggc agatgcaaac agtttgggaa
    12541 ttgctgatgg cactatgtta attggtgact cagtggcttt aagggcaaat acagcactac
    12601 agacagctct tcctggagca cagattaacg cgcaggtcag cgtaacaacc aagaccgcaa
    12661 atgaaatcat gctaaataat agccagaata aatttttacc taagacggtg gtcattgcga
    12721 ctggggtaaa taatcctgag aattacaagg atgactggga cagtatcgtg aaaaatcttc
    12781 ctaagggaca ccatatgatt ttggtgactc cttatgaggg agataagaca aaagagacct
    12841 atgccatcgt tgagaaggct gctgcctata tgagagaatt ggcagagaag acaccttaca
    12901 ttacgatagc agattggaat caagttgcga aagagcatcc agaaatttgg gctggaacag
    12961 accaggttca tttcgggagt gagagtagca ctatcgaagc aggagcaaaa ttgtatgcag
    13021 atacgattgc cacagctttg cagacagctc aagacaagcc ggttaaatca aaataacttg
    13081 tattaaaaaa gagaagagtt ggagaaatcc agctctttta aaatatctcc aaaaaatagg
    13141 tctataccat ttacaaataa aaaagaaagg tttataatgt aattgacata ataaattgta
    13201 gaatcaatct tttaaggagg ttaacattat gcctaactat attaaagcgg atcagttttt
    13261 ctacccacac ggagttcgtc gaggtggtta cttggaactt gtggacggca agtttgggaa
    13321 acatgtagag cagattcctg aaggggctga ggtgattgac tatacaggtt atagcattgc
    13381 cccaggtctt gtggatactc atattcatgg atatgcaggt gtagatgtga tggacaacaa
    13441 cattgaaggt acattgcata ctatgagtga aggacttctt agtaccggtg ttaccagttt
    13501 cttacccaca actttaacag ccacttatga gcaattgctt gcagtcactg aaaatcttgg
    13561 aaaccattat aaagaagcaa caggtgctaa gattcgtggg atttattatg aaggtccata
    13621 tttcacagaa acttttaagg gggcacaaaa tccaacttat atgagagacc cgggtgttga
    13681 ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt aataaaattg cccttgcacc
    13741 agaacgtgat ggggtggaag actttgttcg tacagttacg ggcgaaggtg tgacggttgc
    13801 tcttggacat tcaaacgcga cttttgatga agccaaaaaa gcagtcgatg ctggagcgag
    13861 tgtttgggtg catgcctaca atggaatgcg tgggttgact caccgtgaat tgggtatggt
    13921 tggagccatg taccaattgc cacataccta tgcagagttg atctgtgatg gtcaccacgt
    13981 agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga acagaaaaca tcgctcttat
    14041 cacagactgt atgacagctg ggggattgga agacggagat tatatgttgg gagaattccc
    14101 agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca ggtaacttgg caggttctat
    14161 cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg ggaattgcga atccgcatga
    14221 agcagtcatg atggccagct tcaacccagc taaatccgtt cacatcgatg acgtctgtgg
    14281 ccaaatccgt gaaggctacg acgctgactt catcgtatta gataaagatt tggaattggt
    14341 agcaacctat ctagatggcg taaaacgtta tcaagcataa gagagaaggc agaagttaga
    14401 gactagcttc tgctttttta tacagggtac tttactggta aataaaaagt taaaaaaatc
    14461 acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat tgaactataa atattacaaa
    14521 taaaaaaacg gaggagtgct ttatgaaagc ctatacttat gttaaaccag gacttgcttc
    14581 ttttgttgat gtagacaaac cagttattcg caagccaaca gacgctattg tgcgtattgt
    14641 aaaaaccact atttgtggaa cagacctcca tattatcaaa ggggatgttc ctacttgcca
    14701 aagtggtacc attcttggcc acgaagggat tgggattgtt gaagaagttg gggaaggagt
    14761 ttccaacttc aaaaaaggcg acaaggtctt gatttcttgc gtctgtgcct gtggtaaatg
    14821 ctactactgt aaaaaaggaa tttatgccca ctgtgaagac gaagggggct ggattttcgg
    14881 tcacttgatt gatggtatgc aggctgaata tctacgtgtc cctcatgcag ataatactct
    14941 ttaccatact ccagaagact tgtcagatga agctttggtt atgctgtcag acattctgcc
    15001 tactggatat gaaattggtg tcttaaaagg gaaagtagaa cctggttgca gcgtagccat
    15061 tattggttca ggtccagttg gattggctgc tcttttaaca gcccaattct attcaccagc
    15121 taaattgatt atggtagacc tagacgataa ccgcttggaa actgccctat cattcggtgc
    15181 gactcataag gttaattctt cagaccctaa aaaagccatt aaagaaattt atgatttgac
    15241 agatggtcgt ggtgtggatg tcgctatcga agctgtaggg attcctgaaa catttgattt
    15301 ctgtcaaaag attatcggtg tagacggaac ggttgccaac tgtggtgtgc atggtaaacc
    15361 agttgaattc gatttagata aactttggat tcgcaacatc aatgtaacaa ctggtttggt
    15421 atctacaaat acgactccac aattgttgaa agcacttgaa agtcataaga ttgaaccgga
    15481 aaaattggta actcactatt tcaaactcag tgaaattgaa aaagcctacg aagtcttcag
    15541 taaggcagca gaccaccatg ccattaaggt cattatcgaa aacgatatct cagaagccta
    15601 agtagtaaaa atatttttgt acataagtaa atagaaattc agtcatccat cagatggttg
    15661 gattttttat caaaaaatta agaaatgagc atatttcttt ccttgtctgg cggaattggt
    15721 tataatatac ggtacaaagg aatgaatgaa tatgtatcgt gttatagaaa tgtacggaga
    15781 ttttgaaccg tggtggttct tagaaggttg ggaagaagat attgtagcaa gtagaaaatt
    15841 tgaccagtat tatgatgctc tcaaatacta caaaacttgc tggtttagat tggaacaaga
    15901 atcgcctctt tataaaagta gaagcgactt gatgaccatt ttttgggacc cggaagacca
    15961 acgctggtgt gatgaatgtg atgagtattt acaacaatac cattctttgg ctcttttgca
    16021 ggatgagcag gttatcccag acgaaaaact acgctcaggc tatgaaaaac aaaccagtca
    16081 ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga aaagtaactt tttggagttg
    16141 ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag tatggttcaa
    16201 gaaattgcac aagaaatcat tcgttcggct cggaaaaaag gggcgcaaga catttatttt
    16261 gtccccaagt tagatgccta tgagcttcat atgagggtag gagacgagcg ctgtaaaatt
    16321 ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt tgtggcgggt
    16381 atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc ctatgaccag
    16441 aagatggcgt ctctacgttt atctactgta ggcgattatc gggggcatga gagtttggtt
    16501 atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga tattgaagaa
    16561 ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt tgggagtggt
    16621 aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca agttatgtcc
    16681 atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt gaacgaagca
    16741 atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc agatctcttg
    16801 attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc tagtttgaca
    16861 ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta tgagcgtctg
    16921 ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt ctgctaccag
    16981 agattaatcg ggggaggagg aatcgttgac tttgcaaaca gagattatca agaacaccaa
    17041 gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat cacaagtctt
    17101 caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca ccctatttaa
    17161 caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag ataggagttc
    17221 cttgttggac aagcagtgtg tgacccagat gcgtacaggc ttgtctcagg ggaaatcatt
    17281 ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt tatctctagc
    17341 tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc tagacaatct
    17401 ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt tgctgggttt
    17461 tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg atagtagcaa
    17521 tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg tagggcttgt
    17581 ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga tgagtgtctt
    17641 ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact tgacagccta
    17701 ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc agatttttca
    17761 aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc tggctcaaac
    17821 cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct ttaggaagga
    17881 attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg agttggaaat
    17941 ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca tgaatttggt
    18001 gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg cggcaatgct
    18061 catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg atgacattct
    18121 tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttagtagtc ttgctgatta
    18181 tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg
    18241 acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt tatagcttgg
    18301 ataaaaatga agatgctact ctgagcaagt tacaaggaga tgggcgcatc acggaagaac
    18361 aggttaaagc ttataatgaa tactatacta aaaatggagg ggcaaatcgt aaagtcaatg
    18421 attaaggcct ttaccatgct ggaaagtctc ttggttttgg gacttgtgag tatccttgcc
    18481 ttgggcttat ccagctctgt ccagtccact tttgcagcag tagaggagca gattttcttt
    18541 atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag tcagcaaaag
    18601 actagtctaa atttagatgg gcagacgctt agcaatggca gtcaaaagtt gacagttcct
    18661 aaaggaattc aggcaccatc aggccaaagt attacatttg accgagctgg gggcaattcg
    18721 tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca attatatcta
    18781 ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga ttttactgga
    18841 agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg gacaaattca
    18901 aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa
    18961 gatggccctg cagacggggc aaaatcaggt aagcatcaac ggagttgaga ttcaggtatt
    19021 ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg caatcaaaga
    19081 gccataaggt caaggctttt accttgttag aatccctgct tgccctcatt gtcatcagtg
    19141 ggggattact cctttttcaa actatgagtc agctcctcat ttcagaagtt cgctaccagc
    19201 aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca gaattagacc
    19261 gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat ggcaaggaca
    19321 tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac cgatgctagt ggacgggggt
    19381 atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat caactggttc
    19441 attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt gtggaaaaag
    19501 aagaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat ctttagtctt
    19561 ttgttgcaat tttatttgaa ccgacaaatc gcccactatc aagactatgc tttaaataaa
    19621 gaaaaattgg ttgcttttgc catggctaaa cgaaccaagg ataaagccga gcaagaaagt
    19681 ggggaacagg tttttaatct aggtcaggta agctatcaaa acaagaaaac aagcttggtg
    19741 acgactgttc gtacgtctaa gagccaatat gagtttctgt ttccttcagt caaaatcaaa
    19801 gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa agcggagaaa
    19861 aaaaatcaga agagaagcct gaaaagaaag agaattccta gtcaattcaa ctataatgcg
    19921 ttgaatccag aatagtccac tgtagtttct agaaaattgc tggaaatgga tgttaagctc
    19981 caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaac taaagatatg
    20041 aaacatgatt ttaaccacaa agcagaaact ttcgactccc ctaaaaatat cttcctcgca
    20101 aacttggtat gtcaagcagt cgagaaacag attgatattt tatcagacaa agtaatttta
    20161 gatttcggtg gtggcacggg tctattagcc ttgcccctag ccaagcaggc taagtcagtt
    20221 actcttgtag acatttctga gaaaatgttg gagcaagctc gtttgaaagt ggagcagcaa
    20281 gcaatcaaga atatccagtt tttggagcaa gatttaccga aaaatccctt ggagaaagag
    20341 tttgattgcc ttgctgttag tcgggttctt catcatatgc ctgatttgga tgcggctctc
    20401 tcactgtttc atcaacattt gaaggaagat gggaaactca tcattgctga ttttaccaag
    20461 acagaagcta atcatcatgg atttgattta gctgaactgg aaaacaagct aattgagcat
    20521 ggtttttcat ctgtgcatag tcagattctc tatagcgctg aagacctgtt tcaaggaaat
    20581 cactcagaat tctttttaat agtagcccaa aaatcactcg cctagtcagg gagtgatttt
    20641 tctataagga tggaaaaaag aagggaaatt tgataagata ggaatatgga ttttgaaaaa
    20701 attgaacaag cttataccta tttactagag aatgtccaag ttatccaaag tgatttggcg
    20761 accaactttt atgacgcctt ggtggagcaa aacagcatct atctggatgg tgaaactgag
    20821 ctaaaccagg tcaaagacaa caatcaggcc cttaagcgtt tagcactacg caaagaagaa
    20881 tggctcaaga cctaccagtt tctcttgatg aaggctgggc aaacagaacc cttgcaggcc
    20941 aatcaccagt ttacaccaga tgccattgct ttgcttttgg tgtttattgt ggaagagttg
    21001 tttaaagagg aggaaattac tatcctcgaa atgggttctg ggatgggaat tctaggcgct
    21061 actttcttga cctcgcttga taaaaaggtg gattacttgg gaatggaaat ggatgatttg
    21121 ctgattgatc tggcagctag catggcagat gtaattggtt tgcaggctgg ctttgtccaa
    21181 ggagatgccg ttcgtccaca aatgctcaaa gaaagcgatg tggtcatcag tgacttgcct
    21241 gttggctatt atcctgatga tgccgttgcg tcgcgccatc aagttgcttc tagccaagaa
    21301 catacttacg cccatcactt gctcatggaa caagggctta agtacctcaa gtcagacgga
    21361 tacgctattt ttctagctcc gagtaatttg ttgaccagtc ctcaaagtga tttgttaaaa
    21421 gaatggctga aagaagaggc gagtctggtt gctatgatta gtctgcctga aaatctcttt
    21481 gctaatgcca aacaatctaa gactattttt atcttacaga agaaaaatga aatagcagta
    21541 gagccttttg tttatccact tgctagcttg caagatgcaa gtgttttaat gaaatttaaa
    21601 gaaaattttc aaaaatggac tcaaggtact gaaatataaa atagattttg ttataatagt
    21661 tgaaaacgct taaaaagggg tatcatgtta tgacaaaaac aattgcaatc aatgcaggaa
    21721 gttcaagttt gaaatggcaa ttatacttaa tgccagaaga aaaagtgtta gccaaaggtt
    21781 tgattgaacg tatcggtttg aaagattcaa tttcaactgt aaaatttgac ggccgttctg
    21841 agcaacaaat tttggatatt gaaaatcata cacaagccgt taaaatttta ttggatgact
    21901 tgattcgttt cgatattatc aaggcttatg acgagattac aggtgttgga catcgtgttg
    21961 ttgctggtgg agaatatttc aaagaatcaa cagttgttga gggagatgtt ttagaaaaag
    22021 ttgaagagtt gagtttgttg gctcctctac acaacccggc caatgcagca ggtgttcgtg
    22081 ccttcaagga attgttgcca gacattacca gtgtagttgt ttttgatact tccttccaca
    22141 caagtatgcc agagaaagct tatcgctacc ctctaccaac aaaatattac acagaaaaca
    22201 aggttcgtaa atacggtgct catggtacaa gtcaccagtt tgtagcagga gaagctgcaa
    22261 aactcttggg acgtccatta gaagacttga agttaattac ctgtcatatt ggtaacggag
    22321 gctcaattac agctgtgaaa gccggcaaat ctgtagacac ttctatgggg ttcactcctc
    22381 ttggtggtat tatgatggga acgcgtacag gggatattga tccagctatc attccttatt
    22441 taatgcaata tacagaggat tttaacacac cagaagatat cagtcgtgtt cttaaccgtg
    22501 aatcaggtct tttgggagtt tctgctaatt ctagcgatat gcgcgatata gaagcagctg
    22561 tagcagaagg gaatcacgag gctagcttgg cttatgaaat gtatgttgac cgtatccaaa
    22621 aacatatcgg tcagtacctt gcagtgctaa atggagcaga tgccattgtt ttcacagcag
    22681 gtgtcggtga aaatgcagag aatttccgtc gtgatgtaat ctcagggatt tcgtggtttg
    22741 gttgtgatgt tgatgatgaa aagaatgtct ttggcgttac aggagacatc tcaacagagg
    22801 cagctaaaat ccgtgtcttg gttattccaa cagatgaaga attagtcatt gcccgtgacg
    22861 ttgaacgctt gaaaaaataa gtgaaactaa aaaaatattc aatacaagga gttgggaaag
    22921 ttatttttcc agcttctttt tctgatgaaa ttgtccaaaa ccttgctatg attggctttt
    22981 ttgaaaaata tggtataata gtagtaattt aatagatgga gttgagtttt gaagaaaaac
    23041 tttcgtgtaa aaagagagaa agattttaag gcgattttca aggaggggac aagttttgct
    23101 aatcgcaaat ttgtggtcta ccaattagaa aaccagaaaa accattttcg agtaggtcta
    23161 tcagttagca aaaaactggg gaatgccgtc actagaaatc aaattaagcg acggattcgg
    23221 catattatcc agaatgcaaa agggagtctg gtagaagatg tcgactttgt tgtcattgct
    23281 cgaaaaggag tcgaaacctt gggatacgca gagatggaga aaaatctact ccatgtatta
    23341 aaattatcaa agatttaccg ggaaggaaat gggagtgaaa aagaaactaa agttaactag
    23401 tttgctagga ctgtctctgt taatcatgac agcctgtgcg actaatgggg taactagcga
    23461 tattacagcc gaatcggctg atttttggag taaattggtt tacttctttg cggaaatcat
    23521 tcgcttttta tcgtttgata ttagtatcgg agtggggatt attctcttta cggtcttgat
    23581 tcgtacagtc ctcttgccag tctttcaggt gcaaatggtg gcttctagga aaatgcagga
    23641 agctcagcca cgcattaagg cgcttcgaga acaatatcca ggtcgagata tggaaagcag
    23701 aaccaaacta gagcaggaaa tgcgtaaagt atttaaagaa atgggtgtca gacagtcaga
    23761 ctctctttgg ccgattttga ttcagatgcc ggttattttg gccctgttcc aagccctatc
    23821 aagagttgac tttttaaaga caggtcattt cttatggatt aaccttggta gtgtggatac
    23881 aacccttgtt cttccgattt tagcagcagt attcaccttt ttaagtactt ggttgtccaa
    23941 caaagctttg tctgagcgaa atggcgctac gactgcgatg atgtatggga ttccagtctt
    24001 gatttttatc tttgcagttt atgcgccagg tggagtcgcc ctatactgga cagtgtctaa
    24061 tgcttatcaa gtcttgcaaa cctatttctt gaataatcca ttcaagatta tcgcagagcg
    24121 cgaggccgta gtacaggcac aaaaagattt ggaaaataga aaaagaaaag ccaagaaaaa
    24181 ggctcagaaa acgaaataaa taaggaggaa tctggtaatg gtagtattta caggttcaac
    24241 tgttgaagaa gcaatccaga aaggattgaa agaattagat attccaagaa tgaaggctca
    24301 tatcaaagtc atttctaggg agaaaaaagg ctttcttggt ctatttggta aaaaaccagc
    24361 ccaagtggat attgaagcga ttagtgaaac gactgttgtc aaagcaaatc aacaggtagt
    24421 aaaaggcgtt ccgaaaaaaa tcaatgattt gaacgagcct gtgaagacgg ttagtgaaga
    24481 aaccgttgac cttggtcatg tggttaatgc tattaaaaaa atagaggaag aaggtcaagg
    24541 tatttctgat gaagtcaagg ctgaaatctt aaaacatgaa agacatgcca gcactatctt
    24601 agaagaaact ggtcacattg agattttaaa tgaacttcaa atcgaggaag cgatgaggga
    24661 agaagcaggc gctgatgacc ttgaaactga gcaagatcaa actgaaaatc aagacttgaa
    24721 agagatgggc ttgaaggtcg agcaaagtta tgatattgcc caggtggcta cggatgtgac
    24781 tgcctatgtt caagcgattg tggatgacat ggatgttgag gctacacttt caaatgatta
    24841 taaccgtcgt agcatcaatc tacaaattga caccaacgaa ccaggtcgta ttatcggcta
    24901 ccatggtaaa gtcttgaagg ccttgcaact gttggctcaa aattatcttt acaaccgcta
    24961 ttccaaaacc ttctacgtta caatcaatgt caatgattat gtcgaacacc gtgcagaagt
    25021 cttgcagacc tatgcgcaaa aattggcgaa tcgtgttttg gaagaaggtc gcagtcataa
    25081 aacagatcca atgtcaaata gcgaacgcaa gattatccat cgtattattt cacgtatgga
    25141 tggcgtgact agttactctg aaggtgatga gccaaatcgc tatgttgttg tagatacaga
    25201 ataagtaaaa tcagggttga cctgattttt tgctagttag aggaggttaa actgatgttg
    25261 aataagataa gagactatct agacttttct ggtttgcagt accgtagtcc tgataaagcg
    25321 ggagcagagc gagagaagat gctggcgttc cgccacaaag gacaagaggc ccgaaaggct
    25381 tttacagaac tggccaaagc ctttcaagca agccatccag aatggcaact ccaacagact
    25441 agtcagtgga tgaatcaggc ccagcgtttg agaccacatt tttgggttta tctacagaga
    25501 gacggacaag tgacagaacc tatgatggcc ttacgtttgt atgggacatc tactgacttt
    25561 ggaatttctt tggaagtcag tttcatcgaa cgtaagaagg atgagcaaac actgggcaag
    25621 caggccaaag ttttagacat tccaaccgtt aaagggattt attatctaac ctactctaat
    25681 ggtcaaagtc aacggtggga ggcgaatgaa gaaaagcgtc gtactttacg cgagaaggtg
    25741 agaagtcaag aagttcgaaa agttttagtg aaggtagatg ttcctatgac agaaaattcg
    25801 tctgaagaag aaatcgtaga aggcttattg aagtcttatt ctaaaattct tccctattat
    25861 ctagctacga gaaaataaga taatttgtaa aacatcataa atcatacagt ccaagagtga
    25921 acagtccgct gtgtaattct tggtcttttt gtttgcgctt tcgcattata taataaactt
    25981 acaaaaacaa ttcaaaagga gaacaattat ggaagtcgtt tcaagtgttc taaattggtt
    26041 ttctagcaat attttgcaga atcccgcatt tttcgtaggt ttattggtgt tgataggata
    26101 tgcacttttg aaaaaacctg cccatgacgt tttttcaggg tttgttaaag caacagtagg
    26161 gtatatgttg cttaacgtgg gtgctggtgg tttggttaca acctttcgtc caatcttagc
    26221 agctcttaac tacaaattcc aaattggtgc agcggttatc gacccttatt ttggacttgc
    26281 tgcagcaaac aacaaaattg tagcagagtt tccagatttt gttggaactg caactacagc
    26341 tctattgatt ggttttggaa taaatatctt gctcgtagct cttcgaaaga ttacgaaggt
    26401 aagaaccctc tttattactg gtcacatcat ggtacaacaa gctgcaacag tatctcttat
    26461 ggttctattc ttagtaccac aattgcgcaa tgcttacggt acagcagcga ttggtatcat
    26521 ctgtggactt tactgggcag ttagttcaaa tatgactgtt gaggcaactc aacgcttgac
    26581 tggtggtggc ggatttgcga ttggtcacca acagcaattt gcaatctggt ttgtagataa
    26641 agtagcagga cgctttggta agaaagaaga aagtttagac aatcttaaat tacctaagtt
    26701 cctctcaatc ttccacgata cagttgttgc atctgctacc ttgatgctcg tattcttcgg
    26761 agccattctt ttaatcttgg gtccagacat tatgtctaat aaagaagtca tcacttcagg
    26821 aactctattc aatcctgcta aacaagattt ctttatgtac attatccaaa cagcctttac
    26881 cttctcagtt tacttgttcg ttttgatgca aggtgtccga atgttcgtat ctgagttgac
    26941 aaacgccttc caaggtattt caaacaaatt gttgccaggt tcattcccag cggttgacgt
    27001 tgcagcttct tatggatttg gttctccaaa tgctgtcttg tcaggattta cctttggttt
    27061 gattggtcaa ttgattacaa ttgtcttgct catcgtcttt aaaaatccga ttcttattat
    27121 tacaggattt gtaccagtgt tctttgacaa tgcagccatt gcggtctacg ctgataaacg
    27181 cggcggatgg aaagcggctg ttatcctttc ctttatatca ggtgtccttc aagttgctct
    27241 aggagctctt tgtgtggccc ttctcgattt ggcagcttat ggtggctacc atggaaatat
    27301 cgactttgaa ttcccatggc ttggatttgg atatatcttc aaataccttg gtattgttgg
    27361 ttatgtactt gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg ccaaagcaaa
    27421 agataaagag aaatattaca acggtgaagt tcaagaagaa gcttagtatc tagaaaagga
    27481 gaaataaaat ggttaaagta ttagcagcgt gcggaaatgg aatgggttca tcaatggtta
    27541 tcaagatgaa ggttgaaaat gctctccgta agcttaatca aagagatttt acagtcaatt
    27601 catgcagtgt cggtgaagct aaaggtttag cagtaggata tgacatcgta atcgcttctc
    27661 ttcatttgat tcaagaattg gaagggcgaa ctaatgggaa gttaattggg cttgataact
    27721 tgatggatga taaagaaatc accgaaaaac tcagtcaagc actacagtaa aaggttggag
    27781 ggggctggac agaaactgag agttatcgtt tctgtccttc tccctcttaa ataaaggagg
    27841 cagatatgaa tttaaaacaa gctttaattg acaatgactc gatccgacta ggtttagagg
    27901 ctaacaattg gaaagaagca gtcaaggtag cagtagatcc cttaattgaa agtggggcaa
    27961 ttttgccaga gtattacgat gctatcattg aatcgactga agagtatggg ccttactata
    28021 tcttgatgcc aggtatggct atgccccacg ctagacctga agctggtgtg caaagtgatg
    28081 ccttttcatt gattacctta caaaatcctg ttgtattttc agatgggaaa gaggtatctg
    28141 ttttgttggc actagcagca acaagctcaa aaattcacac aagtgtagcc attccacaaa
    28201 ttattgccct gtttgaatta gaagattcta ttgcacgttt acaggcttgc cagactaaag
    28261 aagatgtctt ggctatgatt gaagaatcta aggatagccc ttatctcgaa ggattggatt
    28321 tggaaagtta gaaagaggaa taaagaaatg acaaaaagaa tacctaattt acaagttgca
    28381 ttagaccatt cagacttgca aggagcgatt aaagcagctg tttctgttgg tcaggaagta
    28441 gatattatcg aagctggaac tgtttgcttg cttcaagttg gaagtgaact ggctgaagtc
    28501 ttgcgtagcc ttttcccaga taagattatt gtggcagaca caaaatgtgc tgatgctggt
    28561 ggaacagttg ctaaaaataa tgcggttcgt ggagcagact ggatgacttg tatctgttgt
    28621 gcaaccatcc ctactatgga agcagctcta aaggctatca agactgaacg aggagaacga
    28681 ggcgaaatcc agatcgagct ttatggcgat tggacttttg aacaagctca gctttggcta
    28741 gatgcaggta tctcacaagc tatttatcac caatctcgtg atgctcttct tgctggtgaa
    28801 acttggggtg aaaaagacct taataaggtt aaaaaactca ttgacatggg cttccgtgta
    28861 tctgtaacag gtggtctaga tgtagatact ctcaaactct ttgaaggtgt tgatgtcttt
    28921 acctttatcg caggtcgtgg aattacagag gctgcggatc cagcaggagc agcgcgtgcc
    28981 ttcaaggatg aaatcaaacg aatttggggg taaatcatgg tacgtccaat tggaatttat
    29041 gaaaaggcaa ccccaacaca ctttacttgg ctagaacgtt taaattttgc caaggagtta
    29101 ggctttgatt ttgtcgagat gtctattgac gaacgtgacg agcgtttagc aagacttgac
    29161 tggagtaagg aagaacgctt ggaagttgtc aaagcaatct atgaaactgg tgttcgtatt
    29221 ccttctatct gtttttcagg ccatcgtcgc tacccattgg gttcaaaaga tccagttcta
    29281 gaggaaaaat ctctagaact catgaaaaaa tgtatcgaat tagctcaaga cttgggagtt
    29341 cgtacgattc aattagctgg ttacgatgtt tactatgagg aaaagtcacc ccagacacgc
    29401 caacgtttta tcaaaaattt gagaaaagcc tgtgactggg ctgaagaagc tcaggtggta
    29461 cttgctattg aaattatgga tgatcctttc atcagtagca tcgaaaaata tttggctata
    29521 gaaaaagaga ttgactctcc cttcctcttt gtatatccag atattggtaa tgtgtctgca
    29581 tggcataatg atatctatag tgagttttat cttggtcatc atgccatcgc agctctccat
    29641 ctcaaggata cttatgcagt gacagaaagt tcaaggggcc agttccgaga tgtacctttt
    29701 gggcaaggtt gtgtcaaatg ggaagaagct ttcgatattt taaaggaaac caattataat
    29761 ggacctttcc taatcgaaat gtggtctgaa aattgtgaaa cagtagaaga aacacgcgca
    29821 gccattcaag aggcgcaagc ttttctctat ccactcatta agaaagcagg tttgatgtaa
    29881 gatgaatcaa gtaatcaatg ctatgcgtaa acgagtctgt gatgccaatc aatcattgcc
    29941 aaaacatgga cttgtcaaat ttacctgggg gaatgtatct gaagtcaatc gcgaactcgg
    30001 tgtcattgtt atcaaaccat caggcgtgga ttatgacgaa ttgacacctg aaaacatggt
    30061 agtgactgat ctagatggta agatcctaga aggggattta agaccatctt ccgacctccc
    30121 aactcatgtg caattatata gggcttggtc agaaattggt agtgtggttc acacccattc
    30181 gacagaagct gttggttggg ctcaggcagg tcgtgatatt cctttctacg gaacaaccca
    30241 tgcagattat ttctacggtt caatcccttg cgcccgtagt ttgaccaagg acgaagtaga
    30301 agtggcctat gaaaaagata ctggcctggt tatcgtagaa gaatttgaac atcgcggact
    30361 taacccggtt gaagtaccag gaattgttgt acgcaatcac ggtccattca cctggggcaa
    30421 aaatccagag aatgctgttt atcactctgt cgtactagag gaagtatcaa agatgaatcg
    30481 ctttacagaa caaatcaatc caagagttgg acctgctccc cagtacatac tagaaaaaca
    30541 ctaccaacgt aaacatggac caaatgctta ttatggtcaa aagtaagaac gatgaaggag
    30601 gagaaaaaga taaatttagc tcctcttttt acatttgatt tttattgaga gtaaagttgg
    30661 agttgaagta attttgaaag attttttaga aatagcgctt gatatatata tggtaaaata
    30721 aaaagaattg ctgtgatatc aatagatttg ggggattttt taatatggta ctggataagg
    30781 caagttgtga tttacttcaa tatttgatgg atcaagaaac gtccaaaacg attatggcga
    30841 tttcgaaaga tttgaaagag tcaagaagga aaatttatta tcacattgac aaaatcaatg
    30901 ctgctctggg tgacgaggcg cttcacatca ttagtattcc acgaattggt attcacttaa
    30961 cggaagagca gagagatgct tgttgtaaac tattatcgga agtagattcg tacgattata
    31021 tcatgagtgc acatgaacgt atgatgataa tgttactatg gataggtatt tctaaagaac
    31081 gtattacgat tgaaaaattg atagagttaa cagaggtatc taggaatact gttctcaatg
    31141 atttgaatag tattcgttat caactaactt tggaacaata tcaggtgatc ttgcaagtga
    31201 gcaagtcaca gggataccac cttcatgccc accctcttaa taaaattcag tatcttcaat
    31261 cgcttctata tcatattttt atggaagaaa atgccacttt tgtatctatt ttagaagata
    31321 agatgaaaga gaggttagat gatgagtgtt tgctttctgt tgaaatgaac caatttttta
    31381 aggaacaggt tcctttagtt gaacaagatt tagggaagaa aataaaccat catgaaataa
    31441 cttttatgtt gcaggttcta ccttatttgc tgttaagctg tcataatgtt gaacagtatc
    31501 aagaaagaca tcaggatata gagcaagaat tttctttgat aagaaaaaga atagagtatc
    31561 aggtgtctaa gaagttagga gaacggttgt ttcaaaagtt tgaaatttct ttgtcaggac
    31621 ttgaagtttc tcttgtagct gttctcctcc tctcctatcg taaagatttg gatattcatg
    31681 cagaaagtga tgattttcgg caattaaaac ttgctttaga agaatttatc tggtattttg
    31741 aatcacaaat ccgaatggag attgagaaca aggatgattt gttacgaaat ttgatgatcc
    31801 actgtaaagc cttgttattt agaaagactt acggtatttt ttctaaaaat cctctaacaa
    31861 aacaaattcg atccaagtat ggagaattat ttttagtcac tagaaaatct gcggaaattt
    31921 tagaaggagc atggtttatt cggctaacag acgatgatat tgcctatttg acgattcata
    31981 ttggaggatt tttaaaatat acaccatcgt ctcaaaaaaa tatgaaaaaa gtttatctcg
    32041 tttgtgatga aggtgttgcg gtttcgagac ttttgctgaa acaatgcaaa ctttattttc
    32101 caaatgagca aattgacact gtatttacaa cagaacaatt taagagtgtg gaagatattg
    32161 cacaagttga tgtagtgatt actactaatg atgatttgga tagcagattt ccgattttaa
    32221 gggttaatcc tatccttgaa gcagaagata ttttgaaaat gctagactat cttaaacaca
    32281 atatatttcg taataagagc aaaagtttca gtgaaaatct ttctagtctt atttcgtctt
    32341 atattgtaga cagcaagttg gctagtaagt tccaagaaga ggttcaaaca cttataaatc
    32401 aagaaatagt agttcaagct tttttggaag atatttgaag gacagtccaa tgatgaacac
    32461 aaacctgtgt ttttcttggt cttttttagt gttttgaagg gtggtatact aatctcaaag
    32521 ataacaatta tatccaaagg aggcaacata tgccaaacgt caaagaaatt acaagagagt
    32581 catggatttt agccactttc ccagagtggg gaacatggtt gaacgaagaa atcgaagaag
    32641 aagtcgtacc tgaaggcaac tttgccatgt ggtggctagg caactgtggt acttggatta
    32701 agacaccagc tggtgctaac gttgtcatgg acctttggtc aaaccgtgga aaatcaacca
    32761 aaaaagtgaa agatatggtt cgtgggcacc aaatggcaaa tatggcaggt gttcgtaagt
    32821 tgcaaccaaa cttgcgtgtt cagccaatgg ttatcgatcc atttgctatc aacgaactag
    32881 actattactt agtttcacac ttccacagtg atcatatcga cccatacaca gctgcagcaa
    32941 ttctcaacaa tcctaagtta gagcatgtta agtttatcgg tccttaccac tgtggacgaa
    33001 tctgggaagg atggggtgtt ccaaaagaac gtatcatcgt tgttaaacca ggtgacacta
    33061 tcgaattaaa agatatgaag attcatgcag tagaatcatt tgaccgtact tgcttggtaa
    33121 ctctcccagt gaacggtgct gatgagacag gcggtgaact tgctggcttg gctgttacag
    33181 atgaagaaat ggctcaaaag gctgttaact atatctttga aacaccaggt ggaaccatct
    33241 atcatggtgc agattctcac ttctcaaact attttgcaaa acatggtaaa gactttaaaa
    33301 ttgatgttgc tttgaataac tatggtgaaa atccggtagg tatccaagac aaaatgacat
    33361 ctatcgacct tcttcgtatg gcagaaaatc tgcgtaccaa agtcattatc ccagttcact
    33421 atgatatctg gtctaacttc atggcttcta ctaatgagat tctagaactt tggaaaatgc
    33481 gaaaagatcg cttgcaatac gatttccatc catttatctg ggaagttggc ggtaagtaca
    33541 cttatcctca agatcaacac ttagtagaat accatcatcc acgtggtttt gatgattgtt
    33601 ttgaacaaga ctctaacatt caatttaaag ctttgctata atataaaaat attctttgga
    33661 ggttatccgt atgttgcatg atacggataa ttttcatata atagtaaaat agaatgtgtg
    33721 attcaataat cacctcaaat agaaaggaaa ttctatgtca aatctatctg ttaatgcaat
    33781 tcgttttcta ggtattgacg ccattaataa agccaactca ggtcatccag gtgtggttat
    33841 gggagcggct ccgatggctt acagcctctt tacaaaacaa cttcatatca atccagctca
    33901 accaaactgg attaaccgcg accgctttat tctttcagca ggtcatggtt caatgctcct
    33961 ttatgctctt cttcaccttt ccggttttga agatgtcagc atggatgaga ttaagagttt
    34021 ccgtcaatgg ggttcaaaaa caccaggtca cccagaattt ggtcatacgg cagggattga
    34081 tgctacgaca ggtcctctag ggcaagggat ttcaactgct actggttttg cccaagcaga
    34141 acgtttcttg gcagccaaat ataaccgtga aggctacaat atctttgacc actatactta
    34201 cgttatctgt ggagacggag acttgatgga aggtgtctca agcgaggcag cttcatacgc
    34261 aggtttgcaa aaacttgata agttggttgt tctttatgat tcaaatgata tcaacttgga
    34321 tggtgagaca aaggattcct ttacagaaag tgttcgtgac cgttacaatg cctacggttg
    34381 gcatactgcc ttggttgaaa atggaacaga cttggaagcc atccatgctg ctatcgaaac
    34441 agcaaaagct tcaggcaagc catctttgat tgaagtgaag acggttattg gatacggttc
    34501 tccaaacaaa caaggaacta atgctgtaca cggcgcccct cttggagcag atgaaactgc
    34561 atcaactcgt caagccctcg gttgggacta cgaaccattt gaaattccag aacaagtata
    34621 tgctgatttc aaagaacatg ttgcagaccg tggcgcatca gcttatcaag cttggactaa
    34681 attagttgca gattataaag aagctcatcc agaactggct gcagaagtag aagccatcat
    34741 cgacggacgt gatccagtcg aagtgactcc agcagacttc ccagctttag aaaatggttt
    34801 ttctcaagca actcgtaatt caagtcaaga tgccttgaat gttgtggcag ctaaattacc
    34861 aaccttccta ggtggatcag ctgaccttgc tcactcaaac atgacttata tcaagacgga
    34921 tggacttcaa gacgatgcca atcgcttgaa tcgtaacatt cagtttggtg ttcgtgaatt
    34981 tgcaatggga acaatcttga acgggatggc ccttcatggt ggacttcgtg tatacggtgg
    35041 aactttcttc gtcttctctg actatgtgaa ggcagctgtc cgcttgtcag ccttacaagg
    35101 acttcctgtg acttatgtct ttacccatga ttcaatcgca gttggggaag atggtccgac
    35161 tcacgaacca gttgagcatt tagcaggtct tcgtgctatg ccaaatctaa atgttttccg
    35221 tccagcagat gcgcgtgaaa cgcaagcagc ttggtacctt gcagtgacaa gtgagaaaac
    35281 accaactgcc cttgtcttga cacgtcaaaa cttgactgtt gaagatggaa cagacttcga
    35341 caaggttgct aaaggtgctt atgttgtata tgaaaatgca gccgactttg ataccatctt
    35401 gattgcgaca ggttcagagg ttaatcttgc tgtctcagct gctaaagaat tggctagtca
    35461 aggcgaaaaa atccgcgtag tcagcatgcc atctacagat gtctttgata aacaagatgc
    35521 agcttacaag gaagaaattc ttccaaatgc agtccgccgt cgtgttgcag tcgaaatggg
    35581 tgcaagtcaa aactggtaca aatatgttgg tctcgatggt gccgttctag gtattgatac
    35641 cttcggagcc tctgccccag caccaaaagt attggcagaa tatggcttta ctgtcgaaaa
    35701 tcttgtaaaa gttgttcgaa atttgaaata atcctaaaaa tcagggcgta agctctggtt
    35761 tttcttacca gaaaagtaag gtacaatctt gtaaaagaag ctgaaatttg atatagtagt
    35821 cctatgtaaa agacaaagga gaaaacaatg aatccaaata ttactttttt aatcatgctt
    35881 gtaggtatga tggccttgat gttctttatg caacgttctc aaaagaaaca agctcaaaag
    35941 cgtatggaaa gcttaaataa actacaaaaa ggctatgaag tgattacaat cggtggactt
    36001 tatggaacag tcgatgaagt agatacggag aagggaacaa tagttcttga cgtagatgga
    36061 gtttacttga cttttgaact agctgctatc aagacagtat taccgctgaa agaaacagct
    36121 tcactagaag gcgcaattga aaaataagac gggatcacga actcccgttt tctataaaag
    36181 aaaggaaatg ggatgaaaaa attagtcttt gtctgtctgg gaaatatttg ccgtagccct
    36241 atggccgagt ttgttatgaa atcaatgaca gataactacg aaatccaaag tcgagcaact
    36301 tcctcttggg aacatggcaa tccgattcat aaggggactc agggaatttt tcaagagtat
    36361 gagattcctt atgacaagaa caagacatcg cttcagatta gtaaggaaga ttttgaagcc
    36421 tttgattata ttatcggaat ggacgcttca aatgtttccg acttacgtca gatgtgtcca
    36481 gtagactgtc aagataagat ttactcattt tcatctgaaa gtgttccaga cccttggtat
    36541 acaggagatt ttgaagaaac ctatcgacgt gttcaagagg gctgtcaagc ttggttagaa
    36601 cgtttagaaa aggagagtta aggtggaaaa tcttacgaat ttttacgaaa agtatcgtgt
    36661 ttatctgact cgtccacgtt tagagatttt gacagtagtt accattgttt tctgtgctgt
    36721 actcgtcttt tttctaaata ttccaggaaa aggtgtctta aaactcgata atggaacgat
    36781 tgtttatgat ggcagtcttg tccgcggtaa aatgaatggc caaggtacca ttaccttcca
    36841 aaatggagac caatatacag gtggcttcaa caatggagcc ttcaacggaa aaggtacctt
    36901 tcaatctaaa gaaggctgga cctacgaagg tgattttgta aatggtcagg ctgaaggaaa
    36961 agggaaacta acaacagaac aagaagtcgt ttatgaagga acttttaaac aaggcgtttt
    37021 tcaacaaaaa taaagcctcc ttatcaaagg aggtattatt agaattacaa ggtaagcgct
    37081 tacctgtaaa tccctttctt tccaaatccc tcttccaagc aagtttgtga aataaaaaat
    37141 atttgaaata aatttcacaa actttaaaga taaaacctga taagaaaaga aaatgagaaa
    37201 agtttcacaa gagtttaaaa attctttgtg aaatgtttat gaaactgttt acaaagttga
    37261 aataatgcgt tataataaac ttgtgaaaaa attaacaaag gatatcgatc cttgaaagct
    37321 atggaggaaa atatggctga taaaaaaact gtgacaccag aggaaaagaa actcgttgct
    37381 gaaaaacacg tagatgagtt ggttcaaaaa gctctagttg cccttgaaga aatgcgtaaa
    37441 ttggatcaag agcaagttga ctacatcgtt gccaaagcat cagtagcagc tttggatgcc
    37501 cacggagaat tggctttaca tgcctttgaa gaaacaggac gtggtgtatt tgaagataaa
    37561 gcaactaaga acttgtttgc ttgtgaacac gtagtaaaca acatgcgcca cactaagaca
    37621 gttggcgtta tcgaagaaga cgatgtaaca ggattgactc ttattgctga accagttggt
    37681 gttgtttgtg gtattactcc aacaacaaac ccaacatcaa cagcaatctt caaatcattg
    37741 atttcattga agacacgtaa cccaatcgtc tttgccttcc atccatcagc acaagaatca
    37801 tctgctcatg cagctcgtat cgtccgcgat gcagctatcg cagctggtgc tcctgaaaac
    37861 tgtgtgcaat ggattactca accatctatg gaagcaacaa gtgcccttat gaaccacgaa
    37921 ggtgttgcga caatccttgc aacaggtggt aatgccatgg ttaaggcggc ttattcatgt
    37981 ggtaaaccag ctcttggggt aggtgccgga aacgttccag cttatgttga aaaatcagca
    38041 aacattcgtc aagcagcaca cgatatcgtc atgtctaaat catttgataa cggtatggtc
    38101 tgtgcatctg aacaagcagt tatcattgat aaagaaattt acgatgaatt tgtagcagag
    38161 ttcaaatctt accacactta ctttgtaaac aaaaaagaaa aagctcttct tgaagagttc
    38221 tgcttcggcg tcaaagcaaa cagcaaaaac tgtgctggtg caaaattgaa cgctgacatc
    38281 gttggtaaac cagcaacttg gattgcagaa caagcaggat ttacagttcc agaaggaaca
    38341 aacattcttg ctgcagaatg taaagaagtt ggcgaaaatg agccattgac tcgtgaaaaa
    38401 ttgtcaccag ttattgcagt tttgaaatct gaaagccgtg aagatggtat tactaaggct
    38461 cgtcaaatgg ttgaatttaa cggtcttgga cactcagcag ctatccacac agctgacgaa
    38521 gaattgacta aagaatttgg taaagctgtt aaagctattc gtgttatctg taactcacct
    38581 tctacttttg gtggtatcgg ggacgtttac aatgccttct tgccatcatt gacacttgga
    38641 tgtggttctt acggacgcaa ctcagttggg gataacgtta gtgccattaa cctcttgaat
    38701 atcaaaaaag tcggaagacg gagaaataac atgcaatgga tgaaacttcc ttcaaaaaca
    38761 tactttgaac gtgattcaat tcaatacctt caaaaatgtc gtgacgttga acgtgtcatg
    38821 atcgttactg accatgccat ggtagagctt ggtttccttg atcgtatcat cgaacaactg
    38881 gaccttcgtc gcaataaggt tgtttaccaa atctttgcgg atgtagaacc ggatccagat
    38941 atcacaactg taaaccgtgg tactgagatt atgcgtgcct tcaaaccaga taccatcatc
    39001 gcactcggtg gtgggtctcc aatggatgct gccaaagtaa tgtggctctt ctacgagcaa
    39061 ccagaagtgg acttccgtga ccttgtccaa aaattcatgg atatccgtaa acgtgccttc
    39121 aagttcccat tgcttggtaa gaagactaaa ttcatcgcga ttccaactac atctggtaca
    39181 ggatctgaag taacaccatt tgccgttatc tctgataaag caaacaaccg taaataccca
    39241 atcgctgact actcattgac accaactgtg gcaatcgtag atcctgcttt ggtattgaca
    39301 gttccaggat ttgttgctgc tgatactggt atggacgtat tgactcacgc gacagaagca
    39361 tacgtatcac aaatggctag tgactacact gatggtttag cacttcaagc tattaaattg
    39421 gtctttgaaa atctcgaaag ctcagttaaa aatgcagact tccactcacg tgagaaaatg
    39481 cataacgctt caacaatcgc tggtatggcc tttgccaatg ccttcctagg tatttctcac
    39541 tcaatggccc ataagattgg tgcgcaattc cacacagttc acggacgtac aaatgccatc
    39601 ttgcttccgt acgttatccg ttacaacggt acacgtccag ctaagacagc aacatggcct
    39661 aagtacaact actaccgcgc agatgaaaaa taccaagata tcgcacgcat gcttggactt
    39721 ccagcttcta ctccagaaga aggggttgaa tcttacgcaa aagctgtcta cgaactcggt
    39781 gaacgtattg ggatccaaat gaattttaga gaccaaggaa ttgacgaaaa agaatggaaa
    39841 gaacattctc gtgaattagc cttcctggct tatgaagacc aatgttcacc agctaaccca
    39901 cgtcttccaa tggtagacca tatgcaagaa atcatcgaag atgcatacta tggctacaaa
    39961 gaaagaccag gacgccgtaa ataattgttt atcagtctag aagcaagaca aaaactcaat
    40021 ttgagggaaa gatccagtaa tttttctatg ataaaaggca tcctatcaag gtttttgaac
    40081 acctgatagg atgccttttt atgatattga ggcctttttg ccctttttga aaaactagaa
    40141 tagaaacaaa atatataata gattgaaact agagtagtac acatctgctt ctaaaacatt
    40201 gttagaa
//
LOCUS       DAVLTG010000014        38868 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLTG010000014 DAVLTG010000000
VERSION     DAVLTG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.014"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            16..1947
                     /locus_tag="VYN12_000776"
     CDS             16..1947
                     /locus_tag="VYN12_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1415193.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQTVADDNEGDENDDADY"
     gene            1934..3250
                     /locus_tag="VYN12_000777"
     CDS             1934..3250
                     /locus_tag="VYN12_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1415194.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3425..4411
                     /locus_tag="VYN12_000778"
     CDS             3425..4411
                     /locus_tag="VYN12_000778"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1415195.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4475..4546
                     /locus_tag="VYN12_000779"
     tRNA            4475..4546
                     /locus_tag="VYN12_000779"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4508..4510,aa:Arg,seq:ccg)
     gene            4729..5427
                     /locus_tag="VYN12_000780"
     CDS             4729..5427
                     /locus_tag="VYN12_000780"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1415196.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5418..8957
                     /gene="smc"
                     /locus_tag="VYN12_000781"
     CDS             5418..8957
                     /gene="smc"
                     /locus_tag="VYN12_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1415197.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALDIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEKDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8954..9748
                     /locus_tag="VYN12_000782"
     CDS             8954..9748
                     /locus_tag="VYN12_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1415198.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLGKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9748..10566
                     /locus_tag="VYN12_000783"
     CDS             9748..10566
                     /locus_tag="VYN12_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1415199.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10570..11859
                     /gene="ftsY"
                     /locus_tag="VYN12_000784"
     CDS             10570..11859
                     /gene="ftsY"
                     /locus_tag="VYN12_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1415200.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVDEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDSEPVVGVSQEEVEEFPHSEELPEEEKLDHE
                     GTIEENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVLEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11905..13392)
                     /locus_tag="VYN12_000785"
     CDS             complement(11905..13392)
                     /locus_tag="VYN12_000785"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1415201.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTAATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(13541..14281)
                     /locus_tag="VYN12_000786"
     CDS             complement(13541..14281)
                     /locus_tag="VYN12_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1415202.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14281..16446)
                     /locus_tag="VYN12_000787"
     CDS             complement(14281..16446)
                     /locus_tag="VYN12_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1415203.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16616..17569
                     /locus_tag="VYN12_000788"
     CDS             16616..17569
                     /locus_tag="VYN12_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1415204.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17646..19634
                     /gene="uvrB"
                     /locus_tag="VYN12_000789"
     CDS             17646..19634
                     /gene="uvrB"
                     /locus_tag="VYN12_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1415205.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVQALD"
     gene            19644..20207
                     /locus_tag="VYN12_000790"
     CDS             19644..20207
                     /locus_tag="VYN12_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415206.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            20173..20661
                     /locus_tag="VYN12_000791"
     CDS             20173..20661
                     /locus_tag="VYN12_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415207.1"
                     /translation="MTVIIKSMETPEEIEDKSLVHWQTWREAYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            20735..21202
                     /locus_tag="VYN12_000792"
     CDS             20735..21202
                     /locus_tag="VYN12_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1415208.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVIYYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(21199..21714)
                     /locus_tag="VYN12_000793"
     CDS             complement(21199..21714)
                     /locus_tag="VYN12_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1415209.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(21726..22253)
                     /locus_tag="VYN12_000794"
     CDS             complement(21726..22253)
                     /locus_tag="VYN12_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1415210.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPIVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(22536..23099)
                     /locus_tag="VYN12_000795"
     CDS             complement(22536..23099)
                     /locus_tag="VYN12_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1415211.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(23083..23634)
                     /gene="coaC"
                     /locus_tag="VYN12_000796"
     CDS             complement(23083..23634)
                     /gene="coaC"
                     /locus_tag="VYN12_000796"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1415212.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(23646..24335)
                     /gene="coaB"
                     /locus_tag="VYN12_000797"
     CDS             complement(23646..24335)
                     /gene="coaB"
                     /locus_tag="VYN12_000797"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1415213.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            24565..26235
                     /locus_tag="VYN12_000798"
     CDS             24565..26235
                     /locus_tag="VYN12_000798"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1415214.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            complement(26726..27892)
                     /locus_tag="VYN12_000799"
     CDS             complement(26726..27892)
                     /locus_tag="VYN12_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1415215.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(27905..28729)
                     /locus_tag="VYN12_000800"
     CDS             complement(27905..28729)
                     /locus_tag="VYN12_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1415216.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            complement(28866..30080)
                     /gene="thiI"
                     /locus_tag="VYN12_000801"
     CDS             complement(28866..30080)
                     /gene="thiI"
                     /locus_tag="VYN12_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1415217.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(30089..31231)
                     /locus_tag="VYN12_000802"
     CDS             complement(30089..31231)
                     /locus_tag="VYN12_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1415218.1"
                     /translation="MIYFDNSATTKPYPEALETYVQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFSPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31369..31803
                     /locus_tag="VYN12_000803"
     CDS             31369..31803
                     /locus_tag="VYN12_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415219.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            complement(31848..34073)
                     /locus_tag="VYN12_000804"
     CDS             complement(31848..34073)
                     /locus_tag="VYN12_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1415220.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(34237..36189)
                     /locus_tag="VYN12_000805"
     CDS             complement(34237..36189)
                     /locus_tag="VYN12_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1415221.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(36186..37097)
                     /gene="pfkB"
                     /locus_tag="VYN12_000806"
     CDS             complement(36186..37097)
                     /gene="pfkB"
                     /locus_tag="VYN12_000806"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1415222.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            complement(37094..37834)
                     /locus_tag="VYN12_000807"
     CDS             complement(37094..37834)
                     /locus_tag="VYN12_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1415223.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            37996..38083
                     /locus_tag="VYN12_000808"
     tRNA            37996..38083
                     /locus_tag="VYN12_000808"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38030..38032,aa:Ser,seq:gga)
     gene            complement(38266..38613)
                     /gene="ssrA"
                     /locus_tag="VYN12_000809"
     tmRNA           complement(38266..38613)
                     /gene="ssrA"
                     /locus_tag="VYN12_000809"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT        11778 a         7510 c         8236 g        11344 t
ORIGIN      
        1 aaaggagtta gattgatgaa taaaagaaaa gttagtttag aagattttta taaatggtat
       61 agtctaaata aagaagagtt attaaataag gcaactgttg gtgaaaagtt taatgataaa
      121 ttaaaagaag agtttctcca ggaatggcct ttggatagga ttttaacaat gtcaatcgat
      181 gaatatgtaa taggaaaggg acagcaaaat aagtctttat gctacgctct tgagaaggga
      241 aaatacaaaa atctatttct tggaatttct ggtggctcag cttcaaaatt tggtatttat
      301 tggaataaaa aaacaaacaa atataaagat caagctaata atgagatttc agagttggat
      361 cagcgatttt caaaattaaa atcagatttg tatgaaatta tcaaagaagg tattcgtttt
      421 aactttgaaa atcctatttt tgatatgaaa agatcaacaa atgaatttat tggtcgttct
      481 gctatggtga caaaattact ttgtatctat actgagggag atcctttctt tggtgtaaat
      541 attaatagtc agaaagaatt ttggaaccac tttgtttctc agacaaatca aggtggacct
      601 tatctgcaaa atcataaaat aattgaacta gtgtccaaaa cttatcctga gttggagcca
      661 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
      721 aatagtacaa tggattcatc aaacaatttt agtcatcaat taactcaatc tctattaaag
      781 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
      841 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
      901 tcctatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
      961 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
     1021 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
     1081 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
     1141 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
     1201 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
     1261 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
     1321 gaaattgata ctgataagaa attcgtcttc atcatcgatg agatcaatcg tggggagatt
     1381 tctaagattt ttggcgaact ctttttttct atcgaccctg gctatcgtgg tgaaaaagga
     1441 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
     1501 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
     1561 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
     1621 gataaagagt tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
     1681 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
     1741 aagttgaagg atgtagattt tgactatgaa ttactctggt ctgattatat taagcctctc
     1801 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
     1861 gcatttgaac tgacaaataa tgagcaaaaa gatcagacag tagctgatga caatgaaggt
     1921 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
     1981 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
     2041 agatgaacgt attttcattt ttccaaatga tttgactcat actcctgatt tggataagga
     2101 ccaaaagatt tttgaaacag tcaatcagaa aatcaagaca gggaacgtga ttggttttct
     2161 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
     2221 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
     2281 tttgtctcgt gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca
     2341 agctgctatt cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtca
     2401 tgttaaggga gtgattgatg taagaagcca tctcaagaaa aatcttcctt tcacgggaaa
     2461 tattgcctac gcaacgagag agttcaccta tgataatccc ctcatgcagt tggtccgtca
     2521 cactattgaa tacattaaga atcagaaaag cattggtcaa ggggtactag ataatctctc
     2581 aactagtcgt gaaaacgtat ctgaaatcgt gcgtgtaacg ccctcttata aactagctga
     2641 tcgtgctaag attactcgga gaaatcaatc taaacctata cgtcatgcat actttcacga
     2701 gtacagaaac ttacaagaac tttgtctgat gatcctaaac caagaaaagc acggtttagg
     2761 gtatcaagat caaaaaatct atggtattct ctttgatgtt gcctggcttt gggaagagta
     2821 tgtttacacc ttgttgccaa aaggttttgt acatcccaga aataaggata agacggatgg
     2881 aatttcagta ttttctgttg ggaaacgaaa agtatatcca gatttttatg acagagaacg
     2941 aaagattgtt ctagatgcaa aatataaaaa actggaattg actgaaaaag gaatcaaccg
     3001 tgaggactta ttccagctga tttcctattc ttatatttta aaagctgaga aggctggact
     3061 tgtttttccg agcaaggaca aggtcattga taatgagata ggaaacctag caggttatgg
     3121 agctttgttg aagaaatggt ctatccaaat tcctcagaag tcttcatctt atagtgcatt
     3181 ttgtaaaatg atggaaaatt cagaagaaaa ttttaaagcg attattgatg aagaagtggg
     3241 gagaaaataa tttcccctct ttcttttatt tttaacacaa gcaaaatccg aacaatatat
     3301 tttaattcat aaaataattt gacaaaaact gtactttggt ttataataaa ttaaggaaac
     3361 gtcggaaaag gcgtagtgat gcgagagcat aggtaggtca ttacaaaaga aacgagacat
     3421 cgatatgtta aatgaatttc caatttttga ttacgaagat attcaattga ttccaaataa
     3481 atgtgtcatt aaaagccgtg cagaagcgga tacaagtgtc actttaggaa atcacacctt
     3541 taaactacct gttgtgccag cgaatatgca gacgattttg gatgaaaatg tagcagagca
     3601 actggctaaa ggtggttact tctacattat gcaccgtttt gatgaggcag gacgcattcc
     3661 ttttattaaa cgaatgcaca atcaagggct cattgcttcc atatctgtcg gtgttaagga
     3721 ctatgagtat gatttcgtta gacagctcaa gactgatgct cctgagtata tcactattga
     3781 tattgctcat ggtcatgcgg atagcgtgat ttctatgatt caacacatca agaaagaatt
     3841 gccagatacc tttgtcattg ctggaaatgt gggaacacca gaagctgtgc gtgaattgga
     3901 aaatgctggt gcggatgcta ctaaggtcgg aatcggtcct ggtaaggttt gtatcaccaa
     3961 ggttaagact ggttttggta caggtggttg gcagttggct gctctacgct ggtgtgccaa
     4021 ggctgcgcgt aaaccgatta tcgctgatgg aggaattcgt actcacggtg atattgccaa
     4081 gtctatccgc ttcggtgcta gcatgatcat gattggttcc ctctttgcag gacatattga
     4141 aagtccaggg aaaacgattg aagtcgatgg tgaacagttc aaagaatatt atggttcagc
     4201 ctcacaatat caaaaaggtg cttacaaaaa tgtggaaggc aaacgtatct tgcttcctgc
     4261 taaaggtcat ctgcaagaca ctttaactga gatggaacaa gaccttcaaa gtgctatttc
     4321 ttatgcaggt ggacgtcagg ttgctgacct taaacacgtt gattatgtga tcgtgaaaaa
     4381 ctccatctgg aatggggatg cttcccacta agacggggtc tttgactaaa aaacttgtta
     4441 ttagagcaaa tttctgttat aataaaacaa gtttccaccc ttagtgtaat ggatatcacg
     4501 taagattccg gttcttgaga tgggggttcg attccctcag ggtggatgta aacattctaa
     4561 aaagccttta atagggcttt tttctttaca ctactctaaa tttgccacta aaactgagaa
     4621 tctctgtcta aagaattccc aaatgctttc cagtcccgtt ttagagtgac tcagggggct
     4681 ttttttgata taataaaaag gactgttatc agttagaaag aggttggtat gaaagaatta
     4741 caaactgtac taaagaacca ttttgcaatc gaatttacag acaaaaagtt actggaaact
     4801 gcctttactc atacgagtta tgccaatgag caccgcctct taaaaatttc acataatgaa
     4861 cgcttggaat ttttaggaga cgctgttcta cagttattga tttcagaata tctgtataaa
     4921 aaatatccta aaaagcctga aggtgaccta tcaaaactcc gtgctatgat tgtccgtgag
     4981 gagagtttag ctggttttgc gcgtgattgc cagtttgacc agtttatcaa gttgggtaaa
     5041 ggggaagaaa aatctggtgg tcgcaatcgt gacaccattc ttggtgatgc ctttgaagcc
     5101 tttcttggtg cccttctttt ggataaggat gtggccaagg tcaaggaatt tatctatcaa
     5161 gtcatgattc ctaaggttga agcaggcgaa tttgagatga ttacagacta taaaacccat
     5221 ctccaagagt tacttcaggt caatggtgat gtggctattc gttatcaggt gatttctgaa
     5281 acagggcctg ctcacgataa ggtctttgat gtagaagttc ttgttgaagg taagagcatc
     5341 ggtcaaggcc aaggtcgttc taagaaatta gcagagcagg aagctgccaa aaatgccgtt
     5401 gagaaggggc tggattcatg tatttaaagg aaatcgaaat tcaggggttc aagtcttttg
     5461 ctgataagac caaggtcgtt tttgaccaag gtgtgacggc agttgttgga cccaatggat
     5521 ctggaaagtc caatattaca gaaagtctgc gttgggcttt gggggagtct agtgtcaaga
     5581 gtctccgtgg gggcaagatg ccggatgtca tctttgctgg aacagaaagt cgcaaaccgc
     5641 tcaattatgc ttctgtagtt gtgactctgg ataatcatga cggatttatc aaggatgcag
     5701 gtcaagaaat cagggtggaa cgccatatct atcgtagtgg agatagcgaa tacaagattg
     5761 acggcaagaa agtccgtctg cgtgatattc atgacctttt cttggataca ggtttgggac
     5821 gagattcctt ctctattatt tcccaaggga aggttgagga gatttttaat tccaagcctg
     5881 aggagcgacg agctattttt gaagaagctg ctggagtttt aaaatacaag actcgcagaa
     5941 aagaaaccga gagtaaactg cagcaaactc aggataatct ggaccgctta gaggacatta
     6001 tctacgagtt ggataatcaa atcaagcctc ttgagaagca agctgaaaat gcccgtaaat
     6061 ttctagactt agaaggtcaa cgcaaggcta tttacttgga tgtattggtt gctcaaatca
     6121 aggaaaataa ggcagaacta gagtcgacag aagaagagtt ggctcaggtt caagaactct
     6181 tgatgagtta ttaccaaaag cgtgaaaaat tagaagaaga aaatcaaact cttaaaaagc
     6241 aacgccaaga tttacaggct gaaatggcca aagaccaagg cagtttgatg gacttgacta
     6301 gtctgattag tgatttagaa agaaaattag ccctatcgaa actggagtcc gagcaagtgg
     6361 ccttgaatca acaggaggca caagctcgtt tggctgcttt ggaggataag agaaattcac
     6421 tcagcaaaga aaagtctgat aaagaaagct ctttagctct gttagaggga aatctagtcc
     6481 aaaataatca aaaactcaat cgtttagaag ctgaattgct ggctttctca gacgatcctg
     6541 atcagatgat tgagctctta cgtgaacgct ttgtagctct tttacaagaa gaagcggatg
     6601 tctcaaacca gttgacccgt attgagaatg agttggaaaa tagtcgtcag ctttctcaaa
     6661 aacaagcaga tcaactagaa aagctgaaag agcaattagc tatagctaaa gagaaggcta
     6721 gtcagcaaaa ggaagagctt gaaactgcca aggagcaggt tcagaaatta ttggctgact
     6781 accaagctat tgccaaggag caagaggagc agaaaacttc ctatcaagct caacaaagcc
     6841 aactctttga ccgtctggat aatctcaaaa acaagcaggc cagagctcaa agtttggaaa
     6901 atatcctgag aaatcatagt aacttttatg caggtgttaa gagtgttctc caagaaaaag
     6961 atcgcctagg tgggattatt ggtgcagtca gtgagcatct gacctttgat atgcattatc
     7021 aaactgccct agacattgcg cttggagcga gtagtcagca cattattgta gaagatgaga
     7081 atgcggcaac caaagccatt gatttcctca aacgaaacag agccggtcgt gcaacctttc
     7141 ttcctttgac cactattaag gcgcgtacga tttctagtca gaaccaagat gctatcgctg
     7201 taagcccagg tttccttggg atggcagatg agttggtgac ttttgatact agactggaag
     7261 ccattttcaa gaacttgcta gctacgacgg ctatctttga taccgtagaa catgcgcgtg
     7321 cagcagctcg ccaagttcgt tatcaggttc gtatggtgac attggatggg acagaattac
     7381 gcacgggtgg ttcctatgcg ggtggtgcca atcgccaaaa taacagtatt ttcatcaagc
     7441 cagaactgga gcaattacaa aaagaaattg ctgcagatga agcaagcttg cgttcagaag
     7501 aagtggcttt gaagaccttg caagatgaga tggccagatt gaccgagtca ttagaagcca
     7561 tcaaatctca aggagagcag gcacgtattc aggagcaagg cttgttcctc gcttatcagc
     7621 aaactagtca gcaagttgaa gaactggaaa ctctttggaa actccaagaa gaggaaaaag
     7681 atcgtctttc cgagggagat tggcaagcag acaaggaaaa ctgccaagag cgtcttgctg
     7741 caatcgccag tgacaagcaa aatctggaag ctgagattga agagattaag tctaacaaaa
     7801 atgccatcca agaacgctat caaaacttgc aggaagagct agcgcaagct cgtttgctta
     7861 agacagaact gcaagggcaa aaacgttatg aagtgactga tattgaacgc ttaggtaagg
     7921 aactagataa tcttgatatt gagcaagaag aaattcagcg ccttcttcaa gaaaaggttg
     7981 acaatcttga gaaagttgat acggatttgc tcagtcaaca ggctgatgaa gccaaaactc
     8041 aaaaaacaaa tctccaacaa ggtttgattc gcaagcagtt tgagttggat gatattgagg
     8101 gtcaactgga tgatattgct agtcatttgg atcaggctcg ccagcagaat gaagagtgga
     8161 ttcgcaagca aactcgtgct gaagcaaaga aagaaaaggt tagcgagcgc ttgcgccatc
     8221 tacaaagtca attaacagac cagtaccaga tcagctacac agaagcttta gaaaaggcgc
     8281 atgagttgga aaatctcaat ctggcagagc aagaagttaa ggatttagag aaggctatac
     8341 gctcactggg tcctgtcaat atagaagcta ttgaccagta cgaagaagtt cacaaccgtc
     8401 tggatttcct aaatagccaa cgtgatgata ttttgtctgc gaaaaacctg cttcttgaaa
     8461 ccatcacaga gatgaatgat gaggtcaagg aacgctttaa atcaaccttt gaggccattc
     8521 gtgagtcctt taaagtgacc ttcaagcaga tgtttggtgg aggtcaggct gacctcattt
     8581 tgactgaagg agacttgctg acagctgggg ttgaaatttc tgtccaacca ccaggcaaga
     8641 aaatccagtc tcttaatctc atgagtggtg gtgaaaaagc cctatcggct cttgccttgc
     8701 tcttctctat cattcgagtt aagactatcc cgtttgttat cttggatgag gtagaggctg
     8761 cgctagacga agccaatgtt aaacgtttcg gggattatct caaccgcttt gataaggaca
     8821 gtcaatttat tgtcgtaacc caccgtaagg ggaccatggc agcggccgat tctatctatg
     8881 gagtgaccat gcaagaatcg ggtgtttcaa agattgtttc agttaagtta aaagatttag
     8941 aaagtattga aggatgacaa ttaaactagt agcaacggat atggacggaa ccttcctaga
     9001 tgggaatgga cgctttgata tggatcgtct caagtctctc ttggtttcct acaaggaaaa
     9061 agggatttac tttgcggtgg cttcgggtcg gggatttctg tctctaggaa aattatttgc
     9121 tggtgttcgt gatgacatta ttttcatcgc ggaaaatggc agtttggtag agtatcaagg
     9181 tcaggacttg tatgaagcga ctatgtctcg tgacttttat ctggcaactt ttgaaaagct
     9241 gaaaacgtca ccttatgtag atatcaataa actgctcttg acgggtaaga aggggtcata
     9301 tgttctagat acggttgatg agacctattt gaaagtgagt cagcattata atgaaaatat
     9361 ccaaaaagta gcgagtttgg aagatatcac agatgacatt ttcaaattta caaccaactt
     9421 cacagaagaa acgttagaag ctggtgaagc ttgggtcaat gataatgtcc ctggtgtcaa
     9481 ggctatgaca actggctttg aatctattga tattgttctg gactatgtcg ataagggtgt
     9541 agctattgtt gaattagcta aaaaacttgg tatcacaatg gatcaggtca tggcttttgg
     9601 agacaatctt aatgacttac atatgatgca ggttgtggga catcctgtag ctcctgaaaa
     9661 tgcacgacct gaaattttag aattagcaaa gactgtgatt ggtcaccata aggaacggtc
     9721 ggttatagct tatatggagg gcttataatg gcagatataa aattgattgc attggacttg
     9781 gacgggacct tgctgactac tgataaaagg ctgacggatc gtaccaagga aaccttgaaa
     9841 gctgcgcgtg atcgtggtat caaggtcgta ttgacaactg gtcgtccctt aaaagccatg
     9901 gatttctttc tccatgagtt agggactgac ggtcaggaag atgagtatac cattactttt
     9961 aatggtggat tagttcagaa aaatacagga gaaatccttg ataaaacagt cttttcatat
    10021 gatgatgtgg cacgtttgta tgaagaaaca gagaaattat cactgcctct tgatgccatc
    10081 tcagaaggaa cagtttatca aatccaatcg gaccaagaaa gtctttatgc caaattcaat
    10141 ccagccttga cctttgttcc agtggacttt gaagacttat ctagtcaaat gacctacaac
    10201 aaatgcgtga ctgcctttgc tcaagaaccc ttggatgcag ccattcagaa gatttctcca
    10261 gaattgtttg accaatatga aatctttaaa tcacgtgaaa tgttgctaga gtggtcacca
    10321 aagaatgttc ataaagcaac aggtttggca aaactaatta gccatcttgg aatcaaccaa
    10381 agccaagtta tggcctgtgg tgacgaggcc aatgacctct ctatgattga atgggcaggg
    10441 ctcggtgttg ccatgcaaaa cgctgttcct gaagtcaagg cagtcgcaaa tgtggtaact
    10501 cctatgacca acgatgagga agctgtcgcc tgggctatcg aagaatatgt gctaaaggag
    10561 aactaagata tgggattgtt tgaccgtcta ttcggaaaaa aagaagaacc taaaatcgaa
    10621 gaagttgtaa aagaagctct ggaaaatctt gatttgtctg aagatgttga tcctaccttc
    10681 acagaagttg atgaagttcc tcaggaagaa gcagaggttg aaattgttga acaagctgtg
    10741 ttccaagaag aggaaatcca agacacagtt gaagaaagtc tggattcaga gccagttgta
    10801 ggggtttctc aagaagaagt cgaagaattt ccacactcag aagaattacc agaggaagag
    10861 aagcttgatc acgaaggaac tatagaagaa aataattctg aagttcttga agcagaaagg
    10921 cctcaagcag aagaaaccgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgcaca
    10981 ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt
    11041 ttcgaggaac tggaagaact gctgattatg agtgatgttg gtgtccaagt cgcttctaac
    11101 ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgcactt
    11161 cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag ctacgatgaa
    11221 agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg
    11281 aaaacaactt ctatcggaaa actagcccac cgctacaaac gagctggtaa gaaggtcatg
    11341 ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga
    11401 cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt
    11461 gatggtatgg aacgtgccgt ggctgaaggt atcgatattc tcatgattga tactgctggt
    11521 cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa
    11581 cgtgttgtgc tagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa
    11641 aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaaccgg aattgttttg
    11701 actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat
    11761 attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca
    11821 gaaaacttta tgaaaggtct cttggaaggt ttaatctaat cagaagcaaa aatcctgcaa
    11881 ggcataaact tgcaggaaat ttttttattc taagcgacca tcttgacgat aggcgatatc
    11941 tggttgccaa gtccatttgg caccgaattt ttcaagtagg tcaaagctgg cttgaggtcc
    12001 catgcttcca gctttatagt catgaagtgg ggcaccattt tcagcccaga gcttttcaat
    12061 acggtcaatt aacttccatg acgcaccaac ttcatcccag tggctaaagt tagttgagtt
    12121 gttatttagg acatcataaa tcaatttttc gtatggttct ggagaagcac cagttgcagt
    12181 cgcagctgta cggtaatcaa gtgagttagg agccaagtta aattcttctc ctacttgctt
    12241 cccatttagg ctaagagaga agccttctgt tggttgaata tagatggtca aaatatttgg
    12301 agcaagtggt tctccaaata tagaatccat ttgtttaaag acgatgttga catgagttcc
    12361 tttttcagtc agtcgtttac ctgtacggaa aaagaaagga acactacgga atcgatcgct
    12421 gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt gattctggat tcacatttgg
    12481 ctcgctacga taagagatgt atttcatgcc atcaatctta ccagagcggt attgcccacg
    12541 gataaagtgt tctttgagtt cttcatcagt tggatgatag aggtttttaa agaccttaat
    12601 cttttcagca cgaatctcgt cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga
    12661 aagaagttgt agagtgtggt tttggaccat gtcacggagg gcaccggatt ggtcatagta
    12721 gccaccacgt tcttctacac ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa
    12781 atccttgttc caaacgtttt caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg
    12841 gatcatttcc ttaccaagat aatggtcgat acggaaaatt tgttcttcgt caaatgttgc
    12901 taggagttcg tcattcaact tgcttgcagt tgcgtaatct gtaccaaatg gtttttcaac
    12961 gatcaagcgc tcaaaacctt tgccatcgac aatgttttca gatttgaggt gtttggcaat
    13021 ggttccaaag aactgaggtg ccatagacaa gaagaagagc ttattgtgtt cagcttggta
    13081 tttttcatta agctcagctt gtaattgacg caaagcaata taatgttccg aatcattgac
    13141 atcatggctt tgatagtaga agtggctagc aaattcttgg gcttgctcgg tactatctgc
    13201 caaatcaagg atggactcga caactacaga ttcaaaatat tccttactcc aaggtctacg
    13261 ggcagttcca ataacggcaa agtgcttgga aagattgccg gatttatata gtctaaaaag
    13321 ggaagggtag agcttgcgtt tagccaggtc tccactcgca ccgaaaattg taacaataac
    13381 cttagatgac atctagctac ctaatttcta tttttattcc tagtcttgct aggtatgagg
    13441 aaacctcatt tcataaactt aattctaaca taattttccg aaaaatcaaa aattccaata
    13501 cgaggtagaa aaactgcaag gaaatcctta cagtttgagt ttagacgttt aagaccttat
    13561 ctaagaactc tttcagacga gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt
    13621 cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc
    13681 ccatctcatg ggttacgata atcatggtca tgccttgctc agccaattcc ttcataacgt
    13741 taagtacgtc tccaaccatc tcagggtcaa gggcagaagt tggttcatcg aagagcatga
    13801 tgtctggatt cattgctagg ccacgagcga tggccacacg ttgtttttga ccacctgata
    13861 ggctatctgg attggcatta gctttatctg ctagtccaac cttttcaagc aactccattc
    13921 ccaattcctc agcttcttcc ttagtcatca acttgtgctc aataggagca aaggtgatgt
    13981 tgtccaatac agacatatga gggaagaggt tgaagtgttg gaataccatg ccgatatttt
    14041 cacggacgtg gtcaacattg gttgtttttt cagttaaatc atagccgttc acagtgatgt
    14101 gaccgctagt gacttcttct aaaagattga ggctacggag gaaagttgac ttaccagaac
    14161 ctgaaggacc gatgatacaa acaacatctc cttcatagaa cttagtcgta attcctttta
    14221 ggacttcatt ttttccatag tgcttgtgta aatcatttac atcaattttt aattttgcca
    14281 ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc aaaagtgtga taattacaag
    14341 atagaagata gcaaggattg catacatctt gaaactttgg tagttacgag caatgataat
    14401 cttaccagtt tggaagagtt caaccaaacc gatagcagat acgatagttg tatctttaag
    14461 agcgataacg aattggttga caaagtttgg caacatcaat ttagttgctt gtggcaagat
    14521 aatcttacgc atggtttttc cataagagat acccaagctt cggctggctt ccatttggcc
    14581 aactggaacg gcctgaatac caccacgaac gatttcagcg atataagcag ccgcattgag
    14641 tgagagggca attgttccag ctacaaagtc gttaattggg ctttgttggc ctgtgataga
    14701 ctcgatgaag tttggaattc cccagaagat gaaggctgca agaatcatca atggaatacc
    14761 acgaataacg tcaacgaaaa tctcagagat gacgcgaaga gatttgtatg ggctaacgct
    14821 aaacataccg aagataattc cgatgacaat ggcaatagca aatgagataa gagctagagc
    14881 aagagtgata ccaagaccgc taaggagttg tttgtagttg ttttgaagca agccccagag
    14941 cgttgtttcg tcaacagtac ttgttgaagc agttgaagat tcgctagcta ggtatttgtc
    15001 aagaatcttt tggaattcac cgtttgcttt aaggtttgca agtccgttgt tgaacatttc
    15061 aatcagttct ggatttgctc cttttttaac ggcaaaggct gtttcaccga ttggagttcc
    15121 agagattgga gttttcaatt tttgaccttg gctgatagaa tatttgagaa caggttcatc
    15181 atccataacg gcatcaatgg caccagtatt taaactgtca tacattgaag aaccatcagc
    15241 aaaggttttg attttgtagc cgtatttgct ttgattttct gttaggaagg tttgagaagc
    15301 agttccgttt ttaacaccga ctgtctttcc ttttagatct tcataagaag caatattgct
    15361 tgattctttg acaccaagaa tggtattagc agtgtagtat gattctgaga agtcaaaagt
    15421 tgccttacga gcatctgtga cagacatacc agcgatgata ccatcggctt gaccagcttg
    15481 gacagcactg atagcagcat caaaaccagg gttggtgatt tcaatttcaa aaccttggtc
    15541 tttagcgatt gccttaatca attccatatc aataccagtg tattggttgc ttgaattttg
    15601 gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata tatttagcct taacaggaat
    15661 ggcttttaat cctgcgagag tagttgtagt tggcactgct gaagatgatg aagcagtcca
    15721 tttcttgata attttatcaa gactaccatc ttttttcatt tcagacaagg cttggttaaa
    15781 ttcagtaacc aggtgctcgt atttacttcc ttttttcaca ccgaaagcaa aacttcctac
    15841 agcttcacca tccatttcaa tatggaggtc ttgaccttgg ttaatggcat attcgataac
    15901 aggtttgtca tccatcatgg catcgatggc accagcactc aagctgttgt tcattaaatc
    15961 accagtgtca aatgttttaa tagtaaagcc gtatttatct ttgattgttt caaggaaacg
    16021 ttgagcggca gttccgtttt taacaccaac ggttttgcca gttaattggt cgtacttgct
    16081 aattttgtgt gactttgtag tagcaatgac aacttttgta tcatagtaag tatcagacat
    16141 ggtgaagact ttttcacgtt ctttagtctt tgtcatccct gccatgatag cgtcggcttg
    16201 cccagcttga accgcattga ctgctgcgtc aaatccagga taggacatct gaatgttcca
    16261 gcctttaatc tcagcgactt tgttaataat gtcaacatca attcctttat aagtttgatc
    16321 tgaatcttta aactcaaaag gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc
    16381 tttggcaata cctaatgaga aaattgggaa taaaattagc aaaaatgcta gaaatttttt
    16441 cttcattttt agtctccttt tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag
    16501 gcaaattttt atatttttcg tgtcagaaaa tataacatcg attttttcct ttccttgaat
    16561 tgctattaaa aagtgctata ataatagtat atatagaaga aaagaggacg gggatatgaa
    16621 gaacaaaaga atatttaaag acttccaagc ttcaaaaatg agtttaaaca tttacacaag
    16681 ccccttgtta gcctttgttt ttgtcttcat aggagagttt gtggctttta ctttgtatgg
    16741 tattggcttg ttagctctca tcggacttgc tagaaatttt ggagaggctg gtcaaaatct
    16801 tgcaagctac ttgcagacct tgcatcagag cttgacggat aaaacaagtg actttcgttt
    16861 aattttagga ttactggcct ttggttttat tcttaacact gtgttcagat ggacaagaaa
    16921 agttgagaaa agacctattc gaaccttggg attttataga gagaatttcc tcagcaatct
    16981 tctgaaagga tttagtctag gcctggcact ttttcttctg accttgttag gtttagtggt
    17041 cttaggtcaa tatcgtttgg aatccattca cttgaatcct tattctcttg cctttgtcgt
    17101 ctttactatc ccattttgga ttttacaggg gacagcagaa gaagtggtgg cccgtgcttg
    17161 gctacttcct caattggcct caagaaccaa tctaaaacta gctattctta tatctagcct
    17221 gttctttacc ctgcttcata tgggcaattc tggtctcacc cctctatctc tagtaaatct
    17281 ctttttattc ggagttgcca tggctcttta ccttctcaaa actgatacag tttggggtgt
    17341 tgcaggtatt catggtgctt ggaattttgc tcagggtaat ctctttggga ttttagttag
    17401 tggtcaaccg tcaggaacgt ctctgatgac ctttttacca caaggcaatc aagattggct
    17461 atcaggtggt tcttttggca tagaaggttc cattatgaca agtctggtat tactactgct
    17521 gattgtctat cttgctaata aattaaagaa agaaaatgaa aggatgtgac ttcggtccgt
    17581 ccttttcttc gtgaaaatac tataagtatg ctaaaatagg aatagcacat ggagagagga
    17641 ttcttatgat caatcacatt acagataatc aatttaaact agtatcaaaa tatcaaccat
    17701 caggagatca accccaagct atcgagcagt tggtggataa cattgagggg ggagaaaaag
    17761 ctcagattct gatgggggcg actggaacag ggaagaccta tactatgagt caggtcattt
    17821 ctaaagtcaa taaaccaact ctggttattg cccacaataa aactctggct ggtcagctct
    17881 atggggagtt taaggaattt ttccctgaaa atgcagttga gtatttcgta tcctactatg
    17941 attattacca gccagaggcc tatgtccctt ctagcgatac ctatattgag aaggatagtt
    18001 ctgtcaatga cgagattgac aagcttcgcc actcagctac ctcagccctt ttggagcgta
    18061 atgatgttat tgtcgtggcc tcagtctctt gtatctatgg tttgggttcg cccaaggaat
    18121 acgctgatag tgtcgttagt ctccgtcctg gtctagagat ttctcgtgat aaactcttga
    18181 atgacttggt cgatattcag tttgaacgta atgatattga tttccaacgc ggaagatttc
    18241 gcgttcgtgg ggatgtggta gagattttcc cagcttcccg agatgaacat gcctttcgag
    18301 tagaattttt tggagacgaa attgaccgta ttcgtgaagt tgaggctctg acaggtcagg
    18361 tgttgggaga agtggatcat ttagcgattt tcccagcgac acactttgtg accaatgacg
    18421 accacatgga agttgccatt gcaaagattc aggccgagtt ggaagaacaa ttagctgtct
    18481 ttgaaaagga aggtaaactg cttgaagccc agcgtttgaa acagcggaca gagtatgata
    18541 tcgaaatgtt acgtgagatg ggctatacca atggggttga aaattattct cgccacatgg
    18601 atggacggag cgaaggagag cctccttata cgcttctcga cttcttccca gatgatttct
    18661 tgattatgat tgacgagagt catatgacca tagggcaaat caagggcatg tacaatggag
    18721 accgttcgcg taaagaaatg ctggttaatt atggtttccg tttgccgtct gctttggaca
    18781 atcgtcctct ccgtcgggag gagtttgaga gtcacgttca tcagattgtt tacgtttcag
    18841 cgacacctgg tgactatgaa aatgaacaga ccgagacagt gattgagcaa atcattcgtc
    18901 caacgggact cttggatcca gaggtggaag tccgtccgac tatgggacag attgatgacc
    18961 tcttgggtga aatcaatgcc cgcgttgaaa aaaatgagcg tacctttatc acaactttga
    19021 ccaagaaaat ggcagaggat ttgaccgact acttcaagga aatgggtatc aaggtcaagt
    19081 acatgcactc ggatatcaag accttggaac ggacggagat tatccgtgac ctgcgcttgg
    19141 gtgtctttga tgtcttggtc ggaattaacc tgctccgtga aggaattgac gttcctgaag
    19201 tgagcctcgt agctattctc gatgctgaca aggaaggttt ccttcgcaac gaacgtggac
    19261 tcatccagac tattggacgt gctgctcgta acagtgaagg ccatgtcatc atgtatgcag
    19321 acacggttac ccagtctatg caacgtgcta tcgatgaaac tgcccgccgt cggaaaattc
    19381 agatggccta taatgaagag catggtatcg taccacagac aatcaagaaa gaaatccgtg
    19441 acctgattgc cgtgaccaag gcagttgcta aggaagagga caaggaagtc gacatcaata
    19501 gcctcaacaa acaagagcgc aaagaactcg tcaagaaact agaaaaacaa atgcaagaag
    19561 ccgtcgaagt gcttgacttt gaactggcgg ctcagatccg tgatatgatg ttggaagtcc
    19621 aggccttgga ttaggggaat agtatgattt atttaagaaa gttaaagaga gaagatttga
    19681 tgtctttatg ggaaatggct tattcacaac ttaatccagt ttggaaacag tatgatgctc
    19741 cctattatga tgattatcag tatttttcaa attttaaaga attcgaacta caaaaatcag
    19801 aatccatttt aagcaactca aatcgccttg gtatttttgt tgatgataaa ctagttggga
    19861 ctgtttcgcg ttattgggta tgtaaacaaa caagatggat ggaattggga attggtattt
    19921 atgataaaaa attctggaac actggtattg ggaaagttgc tatgttgcag tggatagata
    19981 ggacgtttca ggattacttg gagttggagc atctgggttt gacaacttgg tcagggaata
    20041 ttggtatgat gaaacttgct gaaaaattaa gaatgaaaaa agaagctcat attccaaaag
    20101 ttcgttatta tcaaggtaaa tattttgata gtattaaata tggtattttg agagaagact
    20161 gggagaaaat aaatgacggt tattatcaaa tcaatggaaa ctcctgaaga gatagaagat
    20221 aaatcccttg ttcactggca aacgtggaga gaggcttatg atgacctttt gcctgcggaa
    20281 tttcaggata caatgacatt agaaagatgt cgattcttta gtcaaaagta tccagaaaat
    20341 acattgattg cgatggatgg cgtgaaggtg gttggtttta tcagttatgg caattttcgt
    20401 gatgagacta ttcaagctgg tgaaattatt gctttatatg ttttaaaaga ctattatgga
    20461 aaaggtatcg cacaaaagtt aatgaaagca gctttgactg ctcttaatca tttttctgaa
    20521 attttcttat gggtattgaa agataacaag cgcgccattg ctttctatca aaaaatgggt
    20581 tttacttttg atggacaaga aaaaatactt gaacttggaa agcctataaa ggaaaaacga
    20641 atggtgttct attctaaata attttaaaaa agtaaaagat aatatctctg gtagtaagtc
    20701 tgaaaattta ataaattaga aagcgagtaa atttatgtcc cgttcccaat taacaatttt
    20761 aacaaatatc tgtctgattg aagacctcga aactcagcgc gtggtgatgc agtatcgcgc
    20821 ccctgaaaac aatcgctggt ctggttatgc ctttcctgga ggtcatgtag aaaatggcga
    20881 gtctttcgca gagtctgtca ttcgtgaaat ctatgaagaa acagggttga ctatccaaaa
    20941 tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct acattgtcat
    21001 ttattataag gcgactgagt tctctggtag ccttcggtct tcagatgaag gagaagtttc
    21061 ttgggtgcaa aaagaccaga ttccaaactt ggatctggcc tatgatatgc taccattgat
    21121 ggaaatgatg gaagctcccg acaagtcaga gtttttctat cctcgccgta cagaagacga
    21181 ttgggaaaag aaaatcttct agtcttttac taaataacct agctgatcca aggcctcctc
    21241 gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga tgccatctgt
    21301 caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat gttgcacatc
    21361 tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat ggtcaatcaa
    21421 ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac cgatttcttc
    21481 aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa tttgcttata
    21541 gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa ttgcaatgtc
    21601 ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc cattaagggc
    21661 tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg tcatagcttt
    21721 tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt atagtctacc
    21781 atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa catgttttct
    21841 acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc aagggcatga
    21901 acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag ggtatcgggg
    21961 aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa ggcccgaaaa
    22021 acgataacaa tgggatagcc agccatcaaa aatccaaaac tagaggctag gatgacaaaa
    22081 actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct ccccaaagta
    22141 taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa aatcgcaata
    22201 gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt cacaagaatc
    22261 tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa agcaagaatt
    22321 tacttgggtt tatagatcat tttttagtta aaagttatag tagattgaaa ctagaatagt
    22381 ccacctctac ttctaaaaca ttgttagaaa tcgatttggc tgtcctgatc gatttgtcct
    22441 gttcttattt cgttttacta atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    22501 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    22561 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    22621 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    22681 attcctccaa ggacaaagat agtatttgtc aaggaaccaa gggccccagc taaaatcaga
    22741 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    22801 gggacaatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    22861 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    22921 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    22981 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    23041 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    23101 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    23161 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aagtttctaa
    23221 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    23281 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    23341 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    23401 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct tcatgacatc
    23461 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    23521 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    23581 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    23641 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    23701 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg acctgctgaa
    23761 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    23821 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    23881 atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    23941 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    24001 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    24061 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    24121 agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    24181 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg caaaaagcaa agtctctgtg
    24241 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    24301 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    24361 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttatta tagtttcaaa
    24421 ctataaagcc atataaaatt taagaaagga ctctaaaagt cttaaaaaca gagatattta
    24481 cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa tgaattatca
    24541 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    24601 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttacgacga tttggagttg
    24661 tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga gagcaatcca
    24721 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    24781 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    24841 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    24901 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    24961 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    25021 gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    25081 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    25141 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    25201 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    25261 gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa ggatgctatt
    25321 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacatgg tggtccattt
    25381 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    25441 gattacactg ttactgaagc tggttttggt gcggatcttg gtgctgagaa attccttgat
    25501 atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc aacccttcgt
    25561 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    25621 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    25681 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    25741 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    25801 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    25861 aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga aaaaattgtc
    25921 actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac acaaattgct
    25981 caaatcgttc aaaacggttg ggacaaattg ccaatttgta tggctaaaac tcaatacagt
    26041 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    26101 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    26161 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    26221 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    26281 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatcttt
    26341 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagttctatc
    26401 cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    26461 tttcattgag tattaataga ctggtttggt atcctgaaaa ctatatcgta taggtgtcgt
    26521 catggatcct tttagctgat ttaaggatac gaaaacacaa tactatgact aaattgaaat
    26581 gttaaaattc aatttctagc cacctaatcc tgcttcaaat agttatcgaa caagttttat
    26641 gatagctacc ttgttaggat gctcttattt tttaccaaac aaaacaaaag gattaaggga
    26701 gtgaatttcc ttaatccgat agttcttatt cttgacgttg tccgaaatca gcaatcatct
    26761 gatccatttc ttgtcgactc ggagttgtca gcatatacag gtaatctcct tgaagttccg
    26821 cgaaggcagc tggcatgact tttttaacct tgaactgctg gctatatttg gcaagcaaat
    26881 cctcttctga ataaacatag tgagcatttg cacggcgaga agtagccaaa caatactgag
    26941 tttcaaagtc tgacgccggg aactcctctc ctgcgacaat agctgcatag ccacgataaa
    27001 ggtccaagga atgagcaaag ttataaacat caatggtaaa accacctgca gggcggttat
    27061 tgtactcgat ggtaatataa tcgtccccct cacggaagaa ctcaatatgg aaaaaccgtt
    27121 ctttcatacc aaattctttg acaattgctt ccccatactt gcgcagttta ggatccatat
    27181 ccttgagcac ataataagaa ttgtccatct tataaatcat gaggtcaagc ggtgtatagg
    27241 cgtagtcaaa ggttgttgag aagacaatct ttccatcctt gtccacgagc ccgtcaaagg
    27301 tacagatttc gctggaagtg acaaattttt caaagaaata aagggttgaa tggtcccatt
    27361 cttgcttgaa gtgattgata tcgtcttctg tctcaagttt aaaggttgcg gctgctccca
    27421 ctccattatc aggtttggca atcattggaa gaccgatttc tttcactgct tgatcaacat
    27481 ctgcttccgt cttgataaca gctccaggta ccacaggaac acctgctttt ttgaaaagtt
    27541 tcttcatttc agacttatat ttcgtctttt tgagatcctc tggtttggca ccaaaaacat
    27601 tgaattgttc tctgagtgtt gcgtctagct caagccagta ttcattgtga gactcgatgc
    27661 ggtcaattgg accatgttta taaaagagaa aagcaactgc acgtttgact tcatctatgt
    27721 tctcaagatt atcaacacga aaatactcgg tcaagctatt gcgcaagggc tcatccaatt
    27781 gctcgtaaga ctcttgacca attcccaaga ctgtgatgcc tttattagct agttcgatgg
    27841 taaactgttg aaagttttgt ggatagtagg gagaaataac aaggtaattc ataggtaact
    27901 ccttttataa atagagatta ccgaggaaat aaggcatttg tttacgccac cattcccagt
    27961 cgtgggcgac atcatgtccc cattcagcaa accaggctgg aatttgtttc tggtcaaagg
    28021 cttctttgag cttgtaaaag gatggtaaac catcttgttc ccaggctcca agccccgtac
    28081 acagcacaat ctctgcctga cggtaacggt caataaacca gccatcgttt tggttccaaa
    28141 tataatctac tggcgagttt tggtaaatag catcatcgtt gtagtaatcg ccgacaaaga
    28201 aacgtgcgtc gtaaacacca ctgagagcaa tcactttggt aaagacatct ggatgctgga
    28261 ggaagaaatt gagtgcatga taggctccca tagagcaacc tgtcgtcatc atgccatcaa
    28321 accaacctgt tttgtgcttg ataaaaggct tgaccacctc catgacaaac tcagcatact
    28381 ccacaccctt accaccaaac tgctgctctg ggataggaga ttcttggaac ttccaagccg
    28441 catactcatt catccgcccc ataccatcat tgtcaatagc aacgacaatc atgcgactga
    28501 tatccggatt tcgtttgata gctgggataa tcttccatga atgtccaatg aaagactctt
    28561 tgctattaaa aacattttgc ccgtcatgaa agtatacaac aggataggaa cggtctgtat
    28621 ctttctcata atctttagga agaagaatac gtacacggcg ctccttacct gtataaggaa
    28681 ccttgagttt gtgttctttc atttttagat aaaagtagga ttgattcatt gtcagaaaac
    28741 tctctatatt caaaatttta tatcattata tcatgaaaat agaaaaaagt tagtttttta
    28801 cctgttttta gaaaaaaaaa ctaacttttt ttactgattt tcgctattct tttggatttt
    28861 ctgaattaga gtagattatc aatcaagtca tcaacttcat ctttttcggc ttgaggtgtg
    28921 atttcagtaa tcatgattcc agccactgct cgctcaacca agccttcaac atccatacgc
    28981 gcttcgtact gctccgcatt cttaatttta ggatttgttt ttggacgatc tggtgcaaaa
    29041 atggtacaac agtcttcaaa cggttggatt gaaatgtcaa aggtatcgat ttcctgggcg
    29101 atgtcaatga tttccaactt gtccatggta accacaggac gaatgatggg agtgttggta
    29161 acagcattga tagccttcat actttcaagg gtttggctgg ctacttgacc tagactttcc
    29221 ccattgatga taaccaaacc atttcgtacc tcacgaatac ggtcagtaat ccgcatcata
    29281 aagcgacgag ttagagtcat caaataagct tctggcgctt tggctttgat ttcctcttga
    29341 atctctgtga aaggcacctc gataaactgg atatttccgc caaacttggt caatttacgt
    29401 gtcaagtcct gcgctttctt gagggcacca ggactagtat atggtggact agcaaagtga
    29461 actgcctcga tatccacccc acgcttaaga gcaagataac ctgctacagg tgagtcaatc
    29521 cctcctgaca acatgagcat ccctttacct gaagttccaa ctggcaaacc accagcccca
    29581 cgaatggttt cataagaaag ataggctgct tcttcacgaa tctccacctg aagattgatg
    29641 tcaggacttt tcatttgaac ttgcacattt ggaatggctt cgaatacagc ccctccaagt
    29701 gtttggttga gttcacgact atcaagttca aagttgtggt cgctacgctt gctagaaatc
    29761 ttaaaggtca taccttcctt gtagatgtcc cgcataatct cttggacaga agacttcaaa
    29821 acttctacag atttttcaac cttataaaca ggagaaaagt tttgaattcc aaaaacttgt
    29881 ttgagagatt ctgcaactgc tgtgtaatca gctccattga ggtaagcgtg ggcacggtcg
    29941 cgatctgctg ttaccttaac ttgggcatag atagacaaaa cgtccgaaat attattacga
    30001 agtttattga tgaaacgcat acggttttta cccttggttg acaactctcc gtagcgaatc
    30061 ataatttctg aatactgcat gaatgctcct atcttacttt tctagtttga ttgtaaatca
    30121 attttaactt ggtcaaaaac tgctcgacct gactcatatc attttccaag tctaggctaa
    30181 gacgcacagc tgacttggcc ttatctttgt ccactcccat ggcaatcaag gtaccggctg
    30241 gttttcctgc cttagatgaa caagctgagg ttgttgagat gaaaatatca tagtcttcaa
    30301 aggcgtgaac gatgacttca cctcgaacac ctttgattcc aaaagtcaga atatgaggtg
    30361 caaagtcttc ctcatctgaa aagacaaaaa tatccggata gttcagaaga gcttggtgaa
    30421 tcactgcctt catctgccca gtcttgctcc taaagatatc tagcttttcc atagataaac
    30481 ggagagcctt ggctgtcgct gcaatccctg ccacattttc agttgtcgaa cgataatctc
    30541 gctcctggcc accacctgta agaagaggtg taatcttctt gccagatttg atatagacaa
    30601 agccaacacc acggacacca tgaaatttat gactcgagaa ggtcgcgcaa tccacccgtt
    30661 ctgtcagata cttttcagtc ggaattttgg caagcgcctg aaccgcatca acgtggaagg
    30721 aaatagtcgg cttgtctgcc aagaattctg aaatagcctc aataggttgg atagagccga
    30781 tttcattgtt cacagccatg atggaaacga ggattgtatc aggccgtatc aaacctgcta
    30841 acgcctcaac atcgaccaag cctttcttat caactggaga aaaatccact tcaaatcctt
    30901 gacttttcaa ccagagggct gactctttga ctgctggatg ttcaatggct gaaacaatga
    30961 tgtgcttgcc aaactgagct ttttcaaagg ccacaccctt gataacccag ttatcccctt
    31021 ctgttccacc agaggtaaag aagatttcat cgcttttctt accgattaaa tctgcaatct
    31081 gttggcgaga agcatctaag attcgtgttg cttggtctcc caaacgatgg agactagatg
    31141 ggtttcctaa aatttttgaa gcgacctgca cataggtttc aagggcttca ggataaggct
    31201 tggtcgtcgc tgaattatca aagtaaatca tgtttctcac gctttctaaa atcactccct
    31261 ctattgtatc atgaaacgga gcttgcgaca agaaagggca atttctcttt ttttaagatt
    31321 tttttaaaga aacagagtat aataagtcat aatcaaagga gagaatgtat gtctaattat
    31381 cgtagaactt caaaaccaaa aacagaacac atcaaaaaag gctttacagt ctttcaaaaa
    31441 accgttgcga ctatcgctag tatccttggc ttgattaccg ctagtatcac gattatgaac
    31501 gccttggata ataacaaaaa tactaaaaag gaacctacaa caagccagac gacaacaatt
    31561 gtcaaagaaa ttcaaaagga atcccctcag gaaaatacta gtcccaataa ggaaaataag
    31621 acttctcaag aaaaaacaca acaagaagaa acgccaaaat ccagcgtcaa ggaagagaaa
    31681 aaagaagagc agaaaacatc aactcaggat tcttctactc ctgctcctac tccaagtaaa
    31741 cctgctactg aaaacgaaaa acagtccaat accccaactt cggaaaataa aactaatcaa
    31801 taatcactaa aatagcctcc ttccaaactt ggaaagaagc tattttttta ttgttgtaaa
    31861 acttttcttg gtttggtacc ttcagctgga ccaatgacac ctgccatctc aagctcttcc
    31921 atgagacggg tcgcacggtt aaatccaact gacaaacgac gctgaatcat ggatgcactg
    31981 gctttctgtg tttcgataac caaagactta gcttcttcaa aaagcggatc accaccagca
    32041 tctccatccg aaaattctcc ttcattttca gaaacctcac ctggatcaaa actctcatcg
    32101 tagtctgcat ctgcctgagt cttgatgaag ttcacaatgc gctcaacatc gtcatccgag
    32161 ataaaggagc cttggagacg aactggatga ttttcatcaa tcggtttaaa gagcatgtct
    32221 cctcgaccaa gaagtttttc tgctccattt tcatccaaaa tcgtacggga gtctgttcct
    32281 gatgaaaccg caaatgctac acgagatgga acattggcct taatcaaacc agagatgaca
    32341 tcaacagatg gacgctgagt tgcaagaatc atgtggatac ctgcagcacg cgccttctgc
    32401 ccaagacgga tgatagcatc ttccacttcc ttgctggcca ccatcatgag gtcagccaac
    32461 tcatccacaa tcacgacaat gaatggtagc ggaatttgct tgtactcaga ctgggaattg
    32521 aactcttcta ccttggcatt aaaacctgca atattccgaa ctcccacctt ggcaaagagt
    32581 tcataacggt tttccatttc atccacaacc ttttgcagag ccttgctggc tttacgtgga
    32641 ttggtcacga ctggaatcaa gaggtgggga atatcattgt aaacagataa ctcaaccatc
    32701 ttgggatcga ccatcataaa tttaacttga tctggtctcg ccttcatgag aatgctagca
    32761 ataatgccgt taactgctac tgacttccct gaacccgttg aacctgcaac tagcaagtgg
    32821 ggcattttag aaaggtcaaa agctcttgcg gttccattaa cagccttccc taaaggaatt
    32881 tccaagaaat tttctgcttt cgtttgcgat tgttcccata gttctcggaa agatacagtg
    32941 gcaatatcgg agttgggcac ttcaattccg attagggatt tcccagggat tggtgcttca
    33001 atccggacat ctttggcagc caaggctaga gcgaggtcat ctgatagatt ggaaatgcgg
    33061 ttgaccctta caccaacagc cggcttgact tcatacttgg tcactgatgg cccaatttcg
    33121 gcccgttcaa ctgttacctt aataccaaag ctagcaaagg ttgcttctaa gattttgata
    33181 ttttctctga caattttctt ctctttagac tgatcttttg gtttatctgg tgcaaagagt
    33241 tgtaagcttg gaagtttgta ttcaagggct tctttggctg aaaaatcgac ctgaacatct
    33301 tggtcatctg agtcatcttc ctgttcaggg aatttaagtt cagcttgagg caggatgatt
    33361 tctggttcca cccacttttc ttctggaata ggtggaagat tttgaacagc ttcctctgtc
    33421 agaatttcac ccgtttccat atcaacagga ggcaaatcga gtaaggcttt ttcagtctct
    33481 tcttgttcta atctagcctc tttctcagcc ttttggcgag ctttttcttc ttgtttgaca
    33541 aagcgttcct cttttcgacg ctcgtgccct tcccaccatt tggcaaagcc tctactgaaa
    33601 aattcagcaa tatcgtaaac agaccaaggg ctgactagga gagaacccac taaaatcaag
    33661 atagaaccaa taaagtaagt tccgatattt gaaaagagaa aggctgttgg aatataaaga
    33721 gcgaccccga tcaagccccc tccagcaaag ctagtcgttc gaaaaccagt cagatctgtc
    33781 acaacctgag ccatggtccc ttttagaacg gacttgtcca aaccatattt ccaaactaag
    33841 taggcctcaa aaatcaagag taagccagca aatatggtga aaaagccaga taagagtcct
    33901 tcctgttttc gtatccactt gaaaaagaag agatagatta ataggccgaa tatcgccaga
    33961 taagctaggc tacccactag caagcgaatt aaattataaa gggttatacc tgcagcccct
    34021 aatttgaagg ctgcgaaaat caataaaatc gcaattccta atgaaatcaa cattcgttga
    34081 atcgcttctt ttctttccag ttctgcttta gacggtctcc gtcttgttgt acttgtattc
    34141 ttgtttgcca ttcttctatt ataccatatt tcacaggcat ttcgggaaga gaaaaagact
    34201 gcaccaaacg gtccaatctt ttcatttttc tattttttat gcttgtggtt tgcgtaggta
    34261 accataaacc acaccactta cgattgctcc taccaagaca gaaacgaggt aaaggagagc
    34321 atttgaagta agggcgataa cgaagattcc tccgtgtggc gccatgagtt tgataccagt
    34381 aagaccaacg agtccacctg ctactgctga accaaggatg aagcttggaa tcgcacgagc
    34441 tgggtcagcg gcaccaaatg gaatcgctcc ctcagtgata aatgacaagc ccatgatgat
    34501 gtttgtcaaa ccagagttac gttcttcctt agtaaattta tctttgaaaa gaagagttgc
    34561 gacaaagatt gcaagtggtg gcaccattcc tccagccata actgctgcca tggctacaga
    34621 accacctgaa gaaacagttg ctgcaagcgt acctgtacca aagacataag ctgctttatt
    34681 aactggtcca cccatgtcaa cagccatcat tccaccaagg acgataccaa gaaggacagc
    34741 tgaacctcct ccaagaccgc ctaggaagtc attcatagca gtgttgattg cagccattgg
    34801 gatattcaca gctagcataa caaatcctgt caagattgtt ccaagaagtg gcaatagaag
    34861 gattgattta gcaccttcga gtgaacgagg aactttaacg tatttcttga tggcaagaac
    34921 caaggcacct gcgataaatc caccaacaag ggcacctagg aaaccagatg agacacctgc
    34981 aagagttgaa gttgcttcac cacctgcggc ataaggaatt ttaccaaagg caaaaccttc
    35041 tttggcaata gcaccagcca cgaaacctgc taccaaaccc ggtttttcag caatagagta
    35101 ggcaacataa cccgcaaaga ctggaagcat caaaccaaag gcagctccac caattttcat
    35161 aaacatagaa gctaactcat ggtaagaacc aagattgcca aggttttcat ttggaacacc
    35221 caaagcaccg tcaatcaaga aggcaagggc aatcatgata ccaccaccga taacgaatgg
    35281 taacatttga gatacaccac tcatcaagtg tttgtacaag gcaccaccaa ggctttgttt
    35341 ttcgttagag gctgttgcag ctttggcacc attagcggca cggtagactt cagtatctcc
    35401 tgaaagagcc aagttaatta gctcttctgt cttacggata ccgtcagcaa ctggacgatt
    35461 gatcaatggt tttccatcaa atcgatccat ttcaacggcc ttgtctgctg caatgataat
    35521 agctttagcc ttacggatat cttctgcagt tagttgattt ccaacaccgc tagcaccgtt
    35581 ggtttcgacc ttgataccaa cccccatttc agcagctact ttttgaaggg cttcttgggc
    35641 catgtaagtg tgggcaatac ctgttgtaca agctgtaaca gctacgataa agtcaccaga
    35701 gtcattagca ggtgcttgaa caagttcctc agttttttct gaagcttggt caaaaagttc
    35761 gataacttgg cctgcagatg ttgcttgacg aagtttgtct gcaaaaccgt ctttcatcaa
    35821 gtattgagac aattctgcca aggctgccaa gtgagtatca ttggcacctt ctggagctgc
    35881 aatcatgaag aagaggtcag ttgcttgtcc atccaagctc tcgtagtcaa cacccttatt
    35941 tgacttagca aatagaactg tcgcttcttt gacagcagcg tttttgctgt gaggcattgc
    36001 gattccatca cccaaaccag tagaagtcaa agcttcacgc gccaaaattc cttctttaaa
    36061 tgtttcaaaa tctgttacat aaccgtggtc tgtcaaattt ttaatcatct cgtcgatgac
    36121 agctgttttt tcagttgcct gcaaatctag caacatgaca tcttttctca ataggtcttg
    36181 aattttcatc gtttttctac ctcaactttt ccatatgttt ctttaataag ttctgccgtt
    36241 gccaagtcat ctgagaaggt agttgccgtt ccgcaagcca ctccccattt gaaggcttct
    36301 actgcgtctt ttgatttgac aaattcacct gtgaatccag caaccataga atcaccagcc
    36361 ccaactgaat ttttgactgt tcctttgatt ggtttagcaa agtaagctcc ctcagatgtg
    36421 acaagaagag caccgtcccc agccatagag ataataacat tttgagcacc cttagccagt
    36481 aactcacgag cgtatttctc aatttcatct aaactttcga gtttaacccc aaaaatcgct
    36541 ccaagttcat gattgtttgg ttttacaaga agaggctggt agtccaaact atcaattaag
    36601 gtctgtcctt caaagtcaca gaccacttgc gcaccagtct ggcgcgtcaa ggaaatcaaa
    36661 tccttataga taacattgcc tagattttta gcacttgaac ctgcaaagac aactgtatct
    36721 tctactgtca gactagataa aatagctttc aattcttcta gctgaaccgg ttcaacagtt
    36781 ggacccgttc cgttgatttc tgtttcttgg tctgctttga ttttaacatt gatacgagta
    36841 tcttctgcca cttggacaaa acgtgtctcg atttcttcct ctgctagagt atctgtgata
    36901 aatttaccag taaagccacc gataaatccc gtcgctgtat ttggtatatt caaacgtttc
    36961 aagacacggc tgacattgat tcctttccca ccagcaaact tatcatcact gtccatacga
    37021 ttgacactac caactttgac ttggtccaaa cgaacgatat agtcaatgga tggattgagt
    37081 gtgactgtat aaatcatact tctattacct ccgttttctc cttaataacc tgcaagagct
    37141 catgcccttg actagtgata acgatagcgc gtttgagtgg tgctaccttg gcaaagcaag
    37201 tttgtccaat ttttgacgaa tccaccaaga cgtaggtctg cttggcattc tccaaaatag
    37261 ctcttttcac agctccctcc tccatatcag gagtcgtata atagccatcg tcaacaccat
    37321 tcattccgat aaaggcacgg tcaaagtgca attggttaat ctggttaaga gcaacgcccc
    37381 cgatactagc atctgtcgcc gtcttgacgt ttcctccaac catgacagtt ggaatctgct
    37441 tttcaaccaa ctgagcggca tggtgaatgg agttggtcac aactgtaaca ttcttattga
    37501 ccaattcatg aatcaaaaaa gcagttgttg ttccagcatc gataaagatg acatcttttt
    37561 ctttaatgag agaggctgct ttctgagcca gcaacttctt ttcttgaagg tttttgacag
    37621 atttttcttg aatggtttct tcttcctgta aggagtgggg gagttctgct ccaccatgca
    37681 cacgacgaag cttgttttcc gcttccaact catccaagtc tcttcgaacc gttgattctg
    37741 acgtttctag caaactaact aatttttcta gagaaactac atgatgctga tttaactcct
    37801 ctaaaattag ttgtttacgt tctgttttta acactgaatc acctcctgtt atcgtttaca
    37861 ctattcattc tatcatactt tctttcgaag tcaagcattt tttatcattt tctttcaaaa
    37921 tctatcattt ttcttatttc tagaattttt attgcaagat aagagccttt atggtagact
    37981 atttgagtaa gtattggaag attactcaag aggcttaaga ggccgtgttg gaaacgcggt
    38041 aggcgtgtaa tagcgtgcgt gggttcgaat cccatgtctt ccgtcgaaaa aagattattt
    38101 ttaggatgcg acaaatgttg tatccttttt tctatccttt ttttaaaata gggtctgttt
    38161 gtgactccct ttttagcaaa agaatgcaaa ggaataccaa agataaaaat aaaaaacgtt
    38221 gatttaacaa cgttttacca aggaatgcaa aagaatgcaa aggaataatg gagccggtgg
    38281 gagtcgaacc cacgtccaaa cacctgccaa catatttgtc tacaaccata ggttatgtat
    38341 tattttaaca gcccctcgac acataactca agtctagaaa ctgcgagtct atcaatctct
    38401 tatcaagccg ctagacaagg cttaatcgta tctcgctaat aataagacct gtcattgaac
    38461 acgagcaatc caaatcgggt cacgcctgct ggtttttagg cagctagagc gtaagaagtg
    38521 ttattttttg cagttatatt taactgagcg tttacgtcgc cacacgagtc gcaaaatatg
    38581 cctcataatg cctgtcgaat ccgtaacgac cccaaaagac aataaaacca ttatacctta
    38641 tctaactcaa aaatgcaaaa agaaatcaca tacctaagat gaagctatct gttttgaaga
    38701 aattcacgaa gagaattatt ctaaaatact ttcagatgag aattttcgta ctctctttat
    38761 ttcaattcat ttgagtttaa aaactataaa atcaatcctt atattattcg gtctactttt
    38821 cacttattgc accaaaatat agtaaaatga aataagaata gaacgaat
//
LOCUS       DAVLTG010000015        36755 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLTG010000015 DAVLTG010000000
VERSION     DAVLTG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.015"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(1..1920)
                     /gene="tet(M)"
                     /locus_tag="VYN12_000810"
     CDS             complement(1..1920)
                     /gene="tet(M)"
                     /locus_tag="VYN12_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1415224.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            complement(1936..2052)
                     /locus_tag="VYN12_000811"
     CDS             complement(1936..2052)
                     /locus_tag="VYN12_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1415225.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(2297..3232)
                     /locus_tag="VYN12_000812"
     CDS             complement(2297..3232)
                     /locus_tag="VYN12_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1415226.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(3229..4230)
                     /locus_tag="VYN12_000813"
     CDS             complement(3229..4230)
                     /locus_tag="VYN12_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1415227.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            complement(4227..6404)
                     /locus_tag="VYN12_000814"
     CDS             complement(4227..6404)
                     /locus_tag="VYN12_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1415228.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            complement(6407..8854)
                     /locus_tag="VYN12_000815"
     CDS             complement(6407..8854)
                     /locus_tag="VYN12_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1415229.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(8838..9344)
                     /locus_tag="VYN12_000816"
     CDS             complement(8838..9344)
                     /locus_tag="VYN12_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1415230.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            complement(9319..9816)
                     /locus_tag="VYN12_000817"
     CDS             complement(9319..9816)
                     /locus_tag="VYN12_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1415231.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(9933..10154)
                     /locus_tag="VYN12_000818"
     CDS             complement(9933..10154)
                     /locus_tag="VYN12_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415232.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(10197..11402)
                     /locus_tag="VYN12_000819"
     CDS             complement(10197..11402)
                     /locus_tag="VYN12_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV1415233.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(11425..11577)
                     /locus_tag="VYN12_000820"
     CDS             complement(11425..11577)
                     /locus_tag="VYN12_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1415234.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            complement(11580..12965)
                     /locus_tag="VYN12_000821"
     CDS             complement(11580..12965)
                     /locus_tag="VYN12_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1415235.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(12994..13380)
                     /locus_tag="VYN12_000822"
     CDS             complement(12994..13380)
                     /locus_tag="VYN12_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1415236.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(13396..13710)
                     /locus_tag="VYN12_000823"
     CDS             complement(13396..13710)
                     /locus_tag="VYN12_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1415237.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            14383..14682
                     /locus_tag="VYN12_000824"
     CDS             14383..14682
                     /locus_tag="VYN12_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415238.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            14672..15160
                     /locus_tag="VYN12_000825"
     CDS             14672..15160
                     /locus_tag="VYN12_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415239.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            15160..17037
                     /locus_tag="VYN12_000826"
     CDS             15160..17037
                     /locus_tag="VYN12_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEV1415240.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            17058..17300
                     /locus_tag="VYN12_000827"
     CDS             17058..17300
                     /locus_tag="VYN12_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415241.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            17317..18171
                     /locus_tag="VYN12_000828"
     CDS             17317..18171
                     /locus_tag="VYN12_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEV1415242.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            18225..18584
                     /locus_tag="VYN12_000829"
     CDS             18225..18584
                     /locus_tag="VYN12_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEV1415243.1"
                     /translation="MNTCVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            18535..20892
                     /locus_tag="VYN12_000830"
     CDS             18535..20892
                     /locus_tag="VYN12_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1415244.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDSYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEERVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRTFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQAEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            20904..23717
                     /locus_tag="VYN12_000831"
     CDS             20904..23717
                     /locus_tag="VYN12_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1415245.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKARVKQANEDYNHILQNTPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKAAKDNLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLSSVRNIYQKLKAAFSFFTFTAGNPATWIVGGLVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHIKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTVK"
     gene            complement(23752..24360)
                     /locus_tag="VYN12_000832"
     CDS             complement(23752..24360)
                     /locus_tag="VYN12_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415246.1"
                     /translation="MTIQVTPLKQYLENIQVLAPDKTEKQVQELFKTIILENVNFKDN
                     EEMLTYLSDKAPNFEKQHRSRNFIVEETETNNIIGFFSLSLKVVDISDLKESLKKKLV
                     LKGKSPKNIDYLPVLLIGQFGKNTKLNKLSGQELFEIVIQKIEEFRAIVGTQMVFLDS
                     INHPKVIQFYEQFGFVAYSQLIKDDHQVSYQPMALNMSLYKK"
     gene            complement(24362..24526)
                     /locus_tag="VYN12_000833"
     CDS             complement(24362..24526)
                     /locus_tag="VYN12_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415247.1"
                     /translation="MATISLTRDIKLTNEDALKILNHEPSKKLQAVLKSIKSQDATAP
                     TKNKLILKYL"
     gene            complement(24582..24845)
                     /locus_tag="VYN12_000834"
     CDS             complement(24582..24845)
                     /locus_tag="VYN12_000834"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415248.1"
                     /translation="MTYRICKPPSQSVYSGVCHRLAITSKIAIGFCSGVRHRLALMSK
                     ITIRLTMSRPLIYTIILTNMSYKRKRKTYFGFIHYRKHTLSLD"
     gene            24987..25397
                     /locus_tag="VYN12_000835"
     CDS             24987..25397
                     /locus_tag="VYN12_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HEV1415249.1"
                     /translation="MEAIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEIEE
                     GTNPLEKDLQDIDQTSITEPSSVLMEMKQKISDMMESHYKEFIQALISIETGIENQQD
                     LEDLYTYYMRTDAVSLLSSDLEISPQEVEMEIEL"
     gene            25445..31663
                     /locus_tag="VYN12_000836"
     CDS             25445..31663
                     /locus_tag="VYN12_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1415250.1"
                     /translation="MEVIQLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     TKEGKIEEIPHVYSFHQDIVSFLEASSENNDQDLESYTRKFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVFHQNQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKELLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYTQLPLT
                     QKLKIITHFDEVKAIREKSNQVEESLSPSSDIEQETEETNPFSNVDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNGLVRLELFNDSNQLFEENPILYLNSLEEIERVLSHV
                     ELEKEDSEIEMDSSSESQEIDLFSYLEEEKEKFNETESTPLISSLEELDIPVQDFVFP
                     DDLENFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLANEFFD
                     ELNPKYEAERLTLKSLVSKSEYSAMKQSSLTAYYTDPMIIRQIWQKLLDDGFEGGRIL
                     DPSMGTGNFYAAMPRRIREKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVSYQNN
                     SFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDKRT
                     DNVLQEIKSNTHFLGGVRLPDTAFKSIAGTRVTTDLLFFQKDQAKNLNEEELVFSGSI
                     PFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGESETLATDIMKALENVEA
                     PKQIDNSLKAPVFIQEEVDNSIPSRIREDLTLYSFGYEGNQIYYRDTHGIRKSSKVDE
                     ISYYVDEKGDFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGLFKKT
                     IFYESPLSDKDISRIKGMVDLRETYQSLIEIQRHPDYSRTDFQVLLSKLNRDYNRFVS
                     QFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPERVIT
                     RVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRGERKY
                     LSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFKIGSR
                     WIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAKDSSL
                     GVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHLQELF
                     QEFVSQYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAIQRII
                     EEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFPTK
                     KVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLNEL
                     REIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEAHHFK
                     NIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDYKNIVFATGTPVSNSISELYT
                     MMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPELMK
                     IYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDMVKCGTVDPSQD
                     NMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFSDI
                     GTPKKKDNGFDVYSEIKALLVDRGVPSKEIAFVHDANSDEKKNSLSRKVNAGEVRILL
                     ASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYITKGS
                     FDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKMEL
                     ENDLTLLENQRRAFQRSKDHYRHTISYCEENIPILEKRLSKYEGDIQQSEMSKDQSFS
                     MTVGKQAFEQRAEAGESLHRLIRHNQADIKELRTLASYRGFDIKMLSLPTNQPLPETF
                     SVKIVGENRYSVSLDLYSPLGTIQRLQHTIDHIKDDQVKTQNLLDELKDKWTTAKIEI
                     EKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFELD"
     gene            31738..32022
                     /locus_tag="VYN12_000837"
     CDS             31738..32022
                     /locus_tag="VYN12_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415251.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSI
                     RELTSQLEIALQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            32036..32332
                     /locus_tag="VYN12_000838"
     CDS             32036..32332
                     /locus_tag="VYN12_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415252.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFISFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRLINSKTKESM"
     gene            complement(32346..32543)
                     /locus_tag="VYN12_000839"
     CDS             complement(32346..32543)
                     /locus_tag="VYN12_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415253.1"
                     /translation="MKNLKEENLRRALSHIERHRQAINTSNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            32703..33344
                     /locus_tag="VYN12_000840"
     CDS             32703..33344
                     /locus_tag="VYN12_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1415254.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVENKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSIPSLPNTTTK"
     gene            33354..34439
                     /locus_tag="VYN12_000841"
     CDS             33354..34439
                     /locus_tag="VYN12_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HEV1415255.1"
                     /translation="MEIEECRQISILDVASRLGISFKQVSTSVYEHSEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTECRGISEEIIQKMIQQGLIAQASWKTNETVEPVIVFKSYDHRHKL
                     QAASLQGIYKNHSLPRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLISYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVTPSKLLHLINTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLSQSGFPVLLDLPNNESGKEKIDWNDILREKKS
                     DLQLMIENVKETLRNQPVRQTSQCLEL"
     gene            34490..34723
                     /locus_tag="VYN12_000842"
     CDS             34490..34723
                     /locus_tag="VYN12_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415256.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYREQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            34720..35103
                     /locus_tag="VYN12_000843"
     CDS             34720..35103
                     /locus_tag="VYN12_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEV1415257.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            35141..35413
                     /locus_tag="VYN12_000844"
     CDS             35141..35413
                     /locus_tag="VYN12_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415258.1"
                     /translation="MFTKLFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     DQGSEQLKTESTYREETLDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            35484..35960
                     /locus_tag="VYN12_000845"
     CDS             35484..35960
                     /locus_tag="VYN12_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415259.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            35960..36727
                     /locus_tag="VYN12_000846"
     CDS             35960..36727
                     /locus_tag="VYN12_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1415260.1"
                     /translation="MGIQDYTDSEFKQALERNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFARKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSRGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEKLAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQECLFGKWSKVEEEMLKVGEEILETLCNRTE"
BASE COUNT        11728 a         6588 c         7208 g        11231 t
ORIGIN      
        1 ctaagttatt ttattgaaca tatatcgtac tttatctatc cgactatttg gacgacgggg
       61 ctggcaaaca ggttcaccgg tagtaacatg gtaccctttt aactctgtta aacaaacact
      121 acgtccattt gtaaagaaag ttaaatcact acgatattct tgaatacacc gagcagggat
      181 ttctccacta agaatgacct cattattttt caattgagtg tctacgatgt tcgcacaata
      241 tttaggagca tcgttgtatg ctcgtgaaag atattcctgt ggcgcataaa ttttaaaact
      301 aagatatggc tctaacaatt ctgttccagc tttttttaag acttgttcca atacaatagg
      361 agcaagcatc cgaaaatctg ctggggtact aacagggcta tagtataagc catacttaaa
      421 acagatttta cagtccgtca cattccaacc atacaatcct tgttcacagc catagcgtat
      481 cccctccata actgcatttt gaaacgattg atttaagtat ccaagagaaa ccgagctctc
      541 atactgtact ccgctcccta atggaagctg tgctacagat agaccaatgg aagcccagaa
      601 aggattcggt ggaacttcga tgtgaatggt atactctgct ttttttaacg gtctttccat
      661 ataaatgact gtaggctctt ttatttctat ctccacatga tacttttctt gcagcagagc
      721 acaagtcact tccatttgta ctttccctaa gaaagaaagt atgatttcat gtgtcgcaga
      781 atccacataa tatcgcagaa gcgggtcact gtcggagatt tctaaaagtg catcaagtaa
      841 catttccctt tgttgaggtt tgctcggttc aacagtcgtt tgcagcagag ggaggggatt
      901 ttcaattctc tctctctgtg gcaatagctt tgtatctcca agaacactat ttaacttcaa
      961 aaactcattc tgcaaaataa caatttcccc ggaataagcc ttatcgattt tacataattc
     1021 accatttatt gaagtataca tttctgtaat ttttattttt tccttttccg atattctaac
     1081 cgaatctcgc aaatgcagta cgccactata aagacgtata tatgcaagac gctgtctttt
     1141 ttccgaatac tcaattttga aaacttttcc gcaaagttca gactgacctc gatgtgttga
     1201 tgaataaaat ttattcgtaa tcacttctat aaggttatca atccctatat tgttttttgc
     1261 acttccgtga taaacaggga acagggaaca attatgaaat cttatgcttt cctcttgttc
     1321 gagttctaat gcttccaata atttcccaga cgtatatttc tccaaaaggt aatcatttcc
     1381 ttctattacc atatcccatt gttcagattc ggtaaagttc attacacgca tattaggatg
     1441 cagttctacc ttctgtttga ttacaatttc cgcagaaagt ttctctttaa tatcctgata
     1501 aaccgttgat aaatcaattc cattttggtc aatcttattg ataaaaaaga ttgtgggaat
     1561 acctattttc ctaagtgcat gaaacaatat acgagtttgt gcttgtacgc catcttttgc
     1621 agaaatcagt agaattgccc catctaatac tgataatgaa cgatatactt ctgctaaaaa
     1681 atccatatgt cctggcgtgt ctatgatgtt caccttcgta ttttcccact gaaaagaggt
     1741 tattcctgtc tgaattgtaa ttcctctctg acgttctaaa agcgtattat ccgtcctcgt
     1801 tgtacctctg tccacgcttc ctaattctgt aatcgctcca ctgttatata ataagctttc
     1861 tgttaaggta gtttttcccg catcaacatg agctaaaact ccaatattaa taattttcat
     1921 gtgattttcc tccattcaaa agcccaaaag ggcataaaaa tcccagtgat aaatactctt
     1981 atcactggga tttttatgca taaccatagg catacaaagc atacagatat tctccggata
     2041 ctttagaatc acatgataaa ggtattctta aactgggtac aaaaaactaa gccctcctaa
     2101 aaaaggacat ccaattattt gttcccacta tcaaattgac agtttattta agaatacctt
     2161 gccgcatatt tattaactcc ttttaaatag atacttaaat aatagcacat aagagcatat
     2221 ttgtaaagga atctccaatt ttttatcaaa gagagtacgt gattacaaaa tagctgtaat
     2281 aatgtaccaa tatttgttat tctataatct tccaattact cccgttcttt tcaagtacca
     2341 aatcaaattg agatacctgc gttgctttgg tctgctggtc gatatactcc actgtcagcg
     2401 ataccgtgac ttgattatcc ttacgattgt gaataggatt taccagttct tgaaagatgt
     2461 actcttttcc gattggtttt aatatcccgt cattcacata gtaggaaagt tcactggctg
     2521 tcgctgtagg atagagcttg aagaacgtcg ttaaaaactc attgatttca ttggttgtaa
     2581 tggaatcaac cgtcccctca ctttcaatgg cttttggttt ataacttgat ttcttaggta
     2641 tgttggtaat ggtcggattc ttaaccagta ccatatttcc agaaccatct acatagacac
     2701 tcactatata agcagagtgg acggtctttg tattttctcc ctctgtaatg agctggtcta
     2761 cactgtaggt tacattaaac tcattgtcgc cagttggctc taccgtccat atctgaaatc
     2821 ctcttacaga agacgataca ggaatatctt tgcgtactgt atcaacattg agagcttgaa
     2881 gttcatctgt cagatagcct tttagacttt ccattcgatt atcaatggac ttatcggatt
     2941 gctcccatga atagtagact ttcgcaaagt tctctacaaa attttctaca tgatgagtat
     3001 caacgtattc cttttctatg atagttgttt cgtgaatagt atgagtatct atagctgtaa
     3061 agtgcttgaa tatcgcaaag ctgaaactaa gccctaaaag tacccacaag gcaatcacaa
     3121 cctttttatg aggattgacc ttatagtaga cacgaggttt cttttccttt ggtatctgtt
     3181 tttctttatt ctgatttttt ctaaatttca tcattaaatc ttcctttctc attgtttgat
     3241 tcgtcctgct cccactaaat gctgttgcca gtaggggctt gttaagtcgg cataaccgat
     3301 tgggtcgcct gcatgaaaca tacggttatt gccaaggtat atcccaacat gagtaatata
     3361 agagccagcg ttataggtag aatgaaagaa aaccaaatcg ccagcttgtg cttccgatag
     3421 tgggatatgc tgggtcacat catattgctg ttgtgcggtt cgtggtaagt taattccagc
     3481 ttttccatac gtccattgtg tcagtccgct acaatcaaaa gaagtagtcg gggaagctcc
     3541 accgtaaacg tatcgccagc cctcatattt cagtgcttcg tccatgatgg cttgtaccgt
     3601 atcatcatca aactctgttg tgacaagata ctgcgttacc agttgcacat aaaacatatt
     3661 gccatagttg tatcgccagc ccccattgat aggtatggct atgggattgg ggtaagacac
     3721 tttttcgcca cctgaatact cttttgagaa actttgagcc agttcaaagg tatatttatt
     3781 tccacgatta gccacatacc ctaagaaacc accaccataa ttgtaggact ggataaccga
     3841 ttctaaatct acactgagcc tttcgctact ggctaataat tcactgaaat acttcacacc
     3901 ttgcttaatg gattcttctg tactcaatga attaggtgga agaccgaggg attccgagga
     3961 ctgcataaca tcttccgcag taccgcccga ttccacctgt ataatcgcaa gaagtatgtt
     4021 gacatattct tcaacgccat attctttggc atatttttct accataggct tatgagccag
     4081 cacttctgcg gaaacattca cacctccata atgaatattg gaaattccgc tgtcctgttc
     4141 atctgaaaat aaaatggcaa caaacagaag cagtgagaag accatcaaga ataatccaga
     4201 accaccaatc actaaagttt tcaacttcat ggtttcttac cgactttctt aatggtggcg
     4261 gttttgattg gtggtctact tcttgtattt tgtagtggta ctctttgaac agtagacgga
     4321 cgttcttttg tgattggacg ttgtgaagtt ctatctgctg tagtggttga agttgctggc
     4381 ttttgaacgg ttttttcttg aacggtattg ccttggcgtt ccacttttgg acttgaaaaa
     4441 tcggacttaa ctgctggacg ctcttgtttg gcttgttgag attccttata tgaagtctga
     4501 atattagact gttttgaggt ctgttcatca tgatattgtt cttgtcttgt agtcggtctt
     4561 tcatgaacag aagaagcagg ctgttttttc tgtttgacct gttccatttc agagcgacgc
     4621 ttcgcaatgg tttttcgcct ttgttcctgc tgttccttgc gtccactggc tctgtccgct
     4681 ttggtttgag aaatactact ggttaaatca cggacattct cttttacttt ggattttcct
     4741 tgatatactg catatcttgc attggtcggc aaatctttaa cctgttcttt caaaccacta
     4801 gcagtgtcta ccattctgtc tttggtatca gctactgtac cgatggtttg accgatacgt
     4861 tttccaagtg ttgatttttc ctttccgtct ggtcgggagt gatctgcttg tgtccttgca
     4921 gaactccccg aacccgactg tcctttttta cctgtaacaa tggcagaccc agcccctaga
     4981 gtagtcatgg aacgtccaag tttccgctgt agacggtgca tgtgagcgtg cataagcata
     5041 cgaggttttc tcatcacacg acttcccaca ctttgagaat cgttactctg tagagaaaac
     5101 atactcatta aatcgcccag cttgaagtag attcctgcaa aggtcacaat ctgtagaaaa
     5161 gcaatcaaaa agaacggata accagccgat aaggtataga gcatggttga aatactaaat
     5221 gctgtcgtaa taatcaatgt gattccagct cgtgtcaaaa tggtattaaa gagctttgtt
     5281 atggctcgtt ttgacatacc atcaaatgat ggaatcatgc ttaaaataaa gctcacaggc
     5341 agaaacatag catagatgat aaaaagtacc tgcgagaaaa tcatgattcc tgttaatagg
     5401 aatacaaata tggaaatccc aatattgaag acaaatagga agaagactgt acctaaacgg
     5461 ttaatggtct ttgtaatggt tagattggta ttgcttctgt cttcaatttc ttccgcaaca
     5521 attttttctc tgtcttcgcc attgttggaa tctgggctgg tggagagcag gctttccaca
     5581 cggtcaatac cgatactttc aatgtctgaa ctgttgtatt gaagcagtag ccacggttgc
     5641 tgaacctgta tggaaaacag gctatctctg attaagtcca cgctgtcctt gccttgacta
     5701 tcggaatggg gcatgacaat cttcgtgcca agtgataaac tggcattact gatgtctgat
     5761 gaaaagtcat tgattttttt aatgtagtcg ggagcgtagg caataaagga agccgatagg
     5821 ataaacacca gcacaaaatt cataatggca tgaattgcct ttgtggtttc tctctttatc
     5881 agtcccgtat aggcaacata aaccccaaga accaaaatca agagtaagag gaatccaaca
     5941 tagaaaccct ctgttgaaaa tccgtttgca ctcacaccag ctaaggtctg catattctta
     6001 ccaatggaat ctgctgtagc ggaaatgaag tctaaggaat aggcttcctg tactaagtaa
     6061 cctgtcgcat tggaaacata caaactgatt gtccaaataa aattggtaat ggcatatagt
     6121 ccatacatga cctgttttcc aatcccgtcc gaccagttcc acggaagcca gccccagcta
     6181 ttatccacat aaaaatccag ttgatagttt tcaagtgggt atcggctgta ttcatttgcc
     6241 acattgaccg tatcatctac caagcccgca gcttgaacca ccgttcccag catggctaaa
     6301 agaaaaatgg caatcacaag tgtgaaagcc actgtcattg ccactttacc tagacgtttc
     6361 agcgtccagt ttgattttat tctgtttact attgatggtt tcacatttac acctcttttc
     6421 gcacaggtgg tctggtatca aaggcatgga gcagttcttc aaatacaggg tggaactgta
     6481 tcacaccgac acgaccatat aaatcactga taaggcattg cccgttttcc aaatcacgca
     6541 atcgcttctg attgttttcg tcctctgggt ctacaccaaa aaaggctaag gtctttttaa
     6601 tctcgttaag gtcagtggaa cgaaatgcaa attttaagcc gaggttattt ttcagttttt
     6661 catctaagag gtcgtctgta ttttgggtca cgaaatatac cccagcgttc atagcacgac
     6721 cagcccgaac cagcttcata gatagtgttt ttccttgtgc tacctgtaaa aagctccatg
     6781 cttcgtctaa atctacaatc ttgaaaatgc ttcggtctgt atggataaag tctaaagcaa
     6841 aggtactaat gacaatcagc atagcaacgg ataaaagctc catagtggta tattcctcaa
     6901 aggaagtttc cttgtcggga agtaccaagt ccgcaacctg tataatgttc agttgttttt
     6961 ctaagctgat agactgctcc acataaccat tactgaataa taaatgtgca aagtcatagt
     7021 ctgtaaaact ttcgatatgg tcggctatac tggtacttag tggcgtattc tcaacccgta
     7081 attcctcaat cactttcatc aaccctcgta cttcactatt ggttactgca cgaatggctt
     7141 ttctaaggat tgggaagcgt tccccatcac gagaggaaat ccccgtaagg aatgtcagaa
     7201 tatcaatagc cagtgattca gaatctttgg gatttttcat aatcacataa gggtcaagta
     7261 agcctttgtt tttctcatca gaagtcagag tgacgatatt gatttcatgg gaaatctctg
     7321 gcaaggtttc tttccatctg ccacgttctg cttttgggtc tacaatcact gcttgtgccc
     7381 cataaagcac cgcataatag acgataaggt tattcgcaaa ggatttacca ccacccagcg
     7441 aaccaacaaa agccgacgct aacgcattgg ttactgaacc cttaacccct tgactggcaa
     7501 gagcaggttt cagatagaca ttgcgtccag tatctaagct gtagccaaca taaatcccct
     7561 cattttcccc cagcatttga gtagcaccaa aacctaaacc agcgaggaaa tcagaggtca
     7621 cgtattgaat ataatcattc atataacgct tgctggcagg taaaaattct tcatgtaagc
     7681 cgagcatatc cccaaatggt cgtaccagtt ttacgcttaa atcgtcataa aaatctttca
     7741 cttcattaca acgacgtttg agttcgtcaa gatcatttgc tgataccctt accacataag
     7801 acagcttgta catagattcc ttgctttggt ctaaattggt ttccagctca ttcacacttt
     7861 ccagagcttc cgccacattg gagctggttt cattatcact ttgccaagcg tggttatcca
     7921 agtctttcag ttctttcttt ttattgcgga cagtagatag ggctttacga ttcgctacaa
     7981 tttccacatt cattgacgta tcaatcggga atgtaaattg ctgttgctgg tagtagaaga
     8041 tttcagagga cgggaagtcc agttctccga caatgctgtt aatggtaaag taagctacat
     8101 agacggtttc atcttcctgc tggattttca aatatcgctg tttttcttcc accaaacagc
     8161 gagtaggctt aatcaagtca tagtatttaa tcagcgtttc attatccagc tttttctttg
     8221 atagatggta ctcatactct tcataggcag tgcctgtctg tccgtaaagg tgttcaatca
     8281 gatagccgaa gtcgtcctta tctaacctgc ggattttgaa acgacgagag attttatttt
     8341 ctaagagctt ttccatcttc tgaaaacgca ggatttcatc attactcata ctaacaaaat
     8401 cgcccatcag cttatggttc acatcataga caaaatcaga caaagcattt tttgcttcaa
     8461 cggtaagact tttcatagaa aactcctgat cgttgagaag caacttaaag ccgataaaga
     8521 aacggtagtt cacttgattt tcgccaatca tggatattaa agcgtctgtc tgttggtcga
     8581 ttttgtcata ggcaaccgct ttgagcttgc cagtgacttc atttttggaa cgctcttgtg
     8641 cagaacgtat gctggattct gtactgattt gtaaagcatg aattttgcca tcacgatttt
     8701 gtgcgataag ctgtctgaaa gaatcatgca cttgtatttt ctgttctgga cttagaaatg
     8761 agtaattgta aggaacaagc tcatagtaag cataacattc cccgtcttta ttccagacga
     8821 gattgttttc aatgtattta attggatatg ccataaaatt cactcctaac tgctgtaatg
     8881 gcttcttgtg gctggtttct gccaagcgtt actttttttc ctgcataggt cagctttggt
     8941 cgcagtgcat aagcaatgac agacttcaaa aatccataag gctttttacc atcaaaagtt
     9001 tttgtagaca taaaccatgt gaaagccaca ggaatcccaa agtatttgag aaatgctccc
     9061 tctatcatgg aaagaggggg caagttgcca agtatcatca ctgcaaagag tgacacgaca
     9121 aaccatgtca tttgcgtaaa ggttatggga aacggaagtc taaaatcatt gatagaatac
     9181 agtacctttt ccacagacca gatactggta tagcttcgta ttttcttcat gtaatcaatc
     9241 ctttcataaa aaataggggt agctgattga gccaccccgt aaaatagaaa atctgccagt
     9301 agtaatgtac cgacagattt aatagacgat ttcaaaaatc ccatgattgg ttgagataaa
     9361 cgttcctgaa aggtctaaat cccgaccata ggcttgataa tcaatatagt tttgaagact
     9421 agctggtact tcgcctaaag cacccgtttc ttcaatgtag tagcgtgcca cgtcatacat
     9481 atcatcacaa tcggaatgaa tgataatatc ctcttgatgt tcgcttagtt cttcaatgct
     9541 tgaaaaatga gtgagcagag cagatagctc cgattgtaat tcttcgggta attccgatac
     9601 catttcccat agtcgattga gttcgccaat ggaagtgtat tcgtcaaccg taaagggtaa
     9661 ctcgtagtca tgaatggcgt attcctcata ttcatcattc aagccgattt tctctttgac
     9721 ttcctcaaag tcaatgggaa aggtaaacca cgcaccgacc aattcgccct cattgtattt
     9781 gcctaaattc gcaatataga cttgcatatc gtccatatat tcacgtcctt tctttgtaga
     9841 gattcaaaaa tccctaccgc acttcgtttg gtgtaccatt cctttgcgga acataagaaa
     9901 accacttata ttccacaaaa gaacggtttt atttaagcac caataatgcg attgaatagc
     9961 tctagtaaaa tgtcttttac tccagcagcg ttgaagacta agccaaccgc aataatcgca
    10021 ataattaaaa agccaatcag tttgctaaac tcacgcttga agccaagata caagccaatc
    10081 acaacgattg ctaaaagcac cagtgattga gcgtttgata gaaaccagtt ataaaggttt
    10141 tgtccaaaat tcataaaaat gttctcctct ctatattcaa tgaatttgta tttgagttat
    10201 ttttttgttg ttatcacgtc ctgttctttt actgactgtt gcttcaaaat ctgcttgtgt
    10261 cggtctgtca gtttcgcatg gtcgagaatg tcttttacaa cctgcgtctg gttgatttca
    10321 tcaagtttaa tcgcaacctt taaggtcggg gcaacttgat gagatagcca gttcagcgtc
    10381 ctttggaagg agtaaggctc tggttttgtg gttagtttta atcgttcacg attgttccca
    10441 ataaaccaag cccattcttc attcagtttc caatcagaac gaggtttgga atcgtcttta
    10501 tctacaaaac ggatataccg attgataatt ttaaaggcgg tatgctctgg attgtcatag
    10561 acgagtaaat cacggactgc ataataggca cgctcatttt tcaatcgaat ctcaaaacgg
    10621 ttttttactt ctgcgtcttc aatgggaata tcatttttct tgtactgctc gtagtccttt
    10681 tcatagatac agaaataaac ttcactttgt aatgaaccga tatagagggt gtttcccata
    10741 cattcctttt cctctttgcg taccagttcg ccactgcgat agcttttaaa actgcggaag
    10801 acggagatac attcttcctg ttggcacttt tcagtgagta cagggatatt caaaatccct
    10861 gtcttatcgt taatggcaag gtcaaggcgt ttcatcacac cgccagccac caaaacgtcc
    10921 ataaagaact cataccagct tctttgttgt gccagaagat agctttcaaa ttgtctgcac
    10981 ccacgacctt tcaattccac cagaactcct ttgtccagtt catgggagca aaggacgaat
    11041 atgtcgccta aagcataatg ctctgaataa gaatagaaac catagtcctc atgaagaaaa
    11101 taggacagtt tcagttgtaa gatgttttcg accacctgct gtacgtctgt tgtcggaaag
    11161 cgaatcctta cataatcaaa cagcatttca aggggagcgt cgggattgaa gcgttccaga
    11221 gcttcccaaa gggactgctg taaatcctct gatggcttga cttttcctgt ttcaatatcg
    11281 cttagatact gccttgtaat accagtcgca acagctaaac ggttttgaga tagtccataa
    11341 gccaagcgtt tttcttttaa atgctgtaac caagtttgtt cattcagtaa aaatccctcc
    11401 aatcaaaaag gcgtatgtca acttttaaag cccatttgac atacgctgaa attttgtaaa
    11461 tcccttgtaa ccaaaggatt ttctaatgtt tttttgactg tttcctgtcg atttgtaccc
    11521 ccctgttaga tacggggggt taagtgctgg cgtggctatt gccacaccag ccagcaagat
    11581 cagtccacac ctgcgacttc cgcttcgcac gtcgcctgcg tggactgtct gctgttggat
    11641 aactttttaa tttcctccaa gaaatcatat ccttttggta caaggggagt ataaaactct
    11701 gatatgacac ttgttcctac atcaacatag ccacgacctt tgattcgctt taagaagaaa
    11761 tccttttgta cgtcactgcc aaacatcatg ccatagccca tttcagacat acgacctaaa
    11821 gccactctga aattaaactg atcacggatt ccgtcgccta aatattttgc gtctggacgt
    11881 tgacaagcca gtattagaaa gaagccagct tgacgaccta acatgacaat ctgtttcagc
    11941 ttattcataa ctgcggtgtt ttcttttgtt cccagcattt ccatgaaagc gacgtattca
    12001 tcaaagatta agaagtgtgc cgggagacct aagtaagcat aatttttgcc agtcttatag
    12061 ttcttcatct gcttcatttc ctcactacgt ttcatcattt cttcatagaa tgtttcaatg
    12121 caagaaagca agtcttcttt tctatagtag acatttgcca tcacagaacc taagtccgca
    12181 aggtcagcat ttttcgggtc aagaatatac agttttgaat ctgtatgaag caaggcttca
    12241 atcagtgtca gtataaagta agttttaccg ccacctgtac caccagcaat caacatatga
    12301 gggagcttat catattccca ccatacgttt ttcattaagc gaagtttacc atctttagct
    12361 tctacttcat caatagaaat acgactggct atggtgtcat agagcaaagt atattccaca
    12421 taggaatcct ttaactcttt atccgtcagc tcacagtaca agccactctc taatttcttt
    12481 tccaagtgta agagttggtc ttgatatttt cccagcgtga tttccacccg tatctgtatc
    12541 aagccatttt taagtcgata atacatttta gggaagtagg ttatcttttc ctttgtacga
    12601 ccagcactat ctttaaagaa accctctgtt ttgacctgtt cagattcata ccacttgttt
    12661 tcaagtatca tctttgccag tttttgacgg tggtaaagtt gtttaaccgt atcatagcga
    12721 acccgtttga atacaaacgc taccagcaag cagataagaa ttgcgacact gaaactgata
    12781 attaaatagg gaatgtcaat cttatctgct tgtgataggt taaaatcctg ccagttgatc
    12841 tgctggattg tcttcacatg aaacagtccg acaaccagca ggaaaacagg caggagtgac
    12901 gctatcgtaa aatgaaagac taaatcttta ccagatgggc gaatcctttt accacgctgt
    12961 ttcatgcgaa aaagtctcct ttctacctag cgactatttg tcttgtgtcg gttctttctt
    13021 tgcttgtggt tgagctttga atgaactaga atcctttgtc agcacaatat cgtctgcctt
    13081 gatataccag tcaacatctg ctccttgata ggtggcagta gcaacggtgt ccgcaatggg
    13141 attgataagt tccacccgtg cgttataatc aaactctttc aaaggcacgc tggcaggaat
    13201 acttacttga atcatgcgtc cttgtccttt ggattttaag tcataggtac gttccttgat
    13261 ttcatctgaa accgacccgt cttcattttg gattctcact tcacgacgta gagcagagaa
    13321 tttcaattct ccaaaagtcg tgtctttatc taatacaatg ccatttgcta atctcatcat
    13381 ttttcctctc tttctttatt cttttatcat gtcgtcagca tgtaaaaggt aatttgtaaa
    13441 accacgagtg ccgattttgt agccctctgc ggtaatacgt ggattgacta acttcacacg
    13501 ttcctcaaag ccgaaatgtt tttcgccagc ttcagcagga agcaccacca caatatcatc
    13561 tgctctttga acatcagaat agagattata gcttcttgat aagacagtta gccgtccgtt
    13621 gattcttcgc tgaacgactt tatcctcgcc agcaaattct aaattgccga atgttttttc
    13681 catgttggga atcacaaatt taagttccat atttttacct atcctttctt ttttattggc
    13741 tgaatgaatg tttgatggtc ttaaagagtg gggaacgacc ttttgattct tgattttttg
    13801 ttttcataag ttcacttcct ttcaaaatcg ggtaaaaaaa tagacacctc attttttgaa
    13861 gtgtctacct attaaatatt caaattttat tggaagtatc tttatatctt cacttttcaa
    13921 ggataaatcg tcgtatcaaa gctcattcat aagtagtaaa ttagtagtaa attgagtggt
    13981 tttgaccttg ataaagtgtg ataagtccag tttttatgcg gataactaga tttttatgct
    14041 attttttaga caaaattagc ttattttagg gaaatgaaat gctaacgtta tgtaacaatg
    14101 ttagtctttt atttcaaaat ctttgtttag tatgaattta gctctacaga aaaataaaaa
    14161 atgtgataaa aatttcaact actcttctct ataataaagc tacctgttct ttgaaaattg
    14221 aatccactcc gtcttgatta gcgtgcctgt gtaagtaggg actgagagta tttccctgtg
    14281 aagggcaact ggcacaagac gtgtgtgaga attttctaac agacacggag tttatcgtta
    14341 ccagacttaa acgatgcgac aaactagata aaggagttaa tcatgaaggt agtaaacttg
    14401 tatgatttga aacaaatggg aaataaaggt ggttgtacca tccaattgat tcatcacttt
    14461 ccttttggta tgggcttagg acatctcaaa aaagactaca ttgaatttaa acgtgttggt
    14521 atcgttgatg ggaaggcagt agaagtcact cttcgagaac cttattcgag agatctactg
    14581 aaggttgtca agtcgattaa gcaacgtcag aaattgatag cttatcgtta taaagaagga
    14641 aagctgctat ttgtgaagaa ggaggcatca gatgtcctct gaacaacagg aacgaatggc
    14701 agttcaatat gcagagcgta gtcttttatt tactgtaaaa agtcttttaa agattctaga
    14761 atggtctaga cgtcaggctt tagcacagga ttccgcctat aagataggag tgcagaaatt
    14821 agaagaattg ctacaatctc cctatgcgat tgatacgatt aatctgaaaa aagatttttt
    14881 agacaaacca attgatatag agaaatttaa agctttttta gaaaaagaag agattccttt
    14941 agccatcgct tggcaagggg attctctaca tttctacgcg aaagaccgtt cgattttaga
    15001 caatcattta gaccatcttt tagaaaaaat ggttaatgat ccggagaaat tagctgattt
    15061 taccatggat aagtcattag atgatgctat tgatgaagct aaatcccaaa ttacctttag
    15121 acaagaagga gccgtcaaac agaaagagat ggtgagatga tgtacagtgg aaaaaaattc
    15181 ctactattct cactgttagg tatcttacta ggctatcttt ttcatcgttt gacgcttttg
    15241 tatgattcct atactggaaa taccttagat aaatggactc atcttctgat ggaaggtcaa
    15301 gatgaagttc ttcagtcgcc atggaatgtt tcttttactg gaaaatcaag tgcttttttt
    15361 ctactaggtt ttgtgatgat gttactggtt tatctctatc tagagactgg taaaaaacaa
    15421 taccgagaag gggtagaata cgggagcgcc cgttttggaa ctctaaaaga aaagaagctc
    15481 ttttacggta aggaattttc tcatgatacg atcttagcac aagatgttcg tttgacatta
    15541 ttagataaaa aaccacccca atatgataga aataagaata ttgcggtgat tggaggttca
    15601 ggaagtggga agacatttcg ctttgtgaaa cccaatctga ttcagatgaa tagttctaat
    15661 attgtagtgg atcctaaaga tcacttggcc gagaaaacag gcaaactctt tttagaacat
    15721 ggctaccaag taaaggtgtt agatttagtc aatatgaaga actcagatgg ctttaatcct
    15781 tttcgctata tagaaacaga aaacgatttg aatcgcatgc tgactgttta ttttaataac
    15841 accaaaggct ctggctcccg aagtgatcca ttttgggatg aagcttctat gactttggtt
    15901 cgagctttag cctcttactt agtcgatttc tataatccac ctaaaacaag agaacagctc
    15961 atagaagaaa gtcgtttaag tcaaaaggaa tatcaaaact tgttgaaacg tcaaaaaaaa
    16021 gaagtggaag agcgaaaaaa acgaggtcgt tatccaagtt ttgctgaaat ctcaaaactc
    16081 attaaacact tatccaaggg tgaaaaccag gaaaaaagtg tcttagaaat tctatttgaa
    16141 aattatgcta aaaagtatgg gactgaaaat tttaccatgc gaaattgggc agattttcaa
    16201 aattataagg ataagactct ggattctgtt atagctgtaa ccactgctaa atttgccctc
    16261 ttcaatattc aaagtgtcat ggacttgacc aaaagagata cccttgatat gaagacatgg
    16321 ggcaaggaaa aatcaatggt ttacttagtt atcccagata acgatagtac ctttcgcttt
    16381 ctttcagccc tctttttttc aaccgtattt caaaccctaa caagacaagc agatattgat
    16441 tttaagggtc aattgcctct tcatgtgaga gtttacttag atgagttcgc aaatatcgga
    16501 gaaattccag attttgctga acaaacctca acagtccgtt ctcgaaatat gagtctcgtt
    16561 cctattcttc aaaatattgc ccaacttcaa gggctctata aagaaaaaga agcttggaaa
    16621 accattttgg ggaactgtga tagcttagtc tacttaggtg gtaatgatga agataccttt
    16681 aaatttatga gtggcttact cggtaaacaa accattgatg ttcgaaatac tagtcgttcc
    16741 tttggccaaa caggttcagg atccctttct catcaaaaga ttgctcgtga cttaatgaca
    16801 cccgatgagg tcggaaatat gaaacggcat gaatgcttgg ttcgaattgc caatatgcct
    16861 gtctttaaaa gcaaaaaata caattccact aagcatccaa actggaagta cctagctaat
    16921 caagaaagcg atgaacggtg gtggaactat caaatcaatc ctttgaatca aagacaagaa
    16981 aattatcttg acgaccttag aattcgtgat ttaacttttg aatctagttt aaaataaaaa
    17041 tagaaaagag gaaatagatg attacgcatt ttaaaggttt tgtttatgga gtagacgcaa
    17101 gtgctatgtt tgcacaagct atgtctttgt tacagaaggg attgattgca gttggtgcct
    17161 ttctcgttgt tgtggggatt gtcaaccttg caaccaacat taaagatggt ggaccaggtg
    17221 ttcggaatgc cattcttgaa attgtcggtg gtgttatggt aggggctgct ggagcctttg
    17281 taacccagat ttcaatttag gaggataaac aatgacatga atcttagttt agtctcaccc
    17341 tttgtttacc ttgcatctga aaaaatatca gctgaaaatt tatttgaagg atttaatgtg
    17401 gatttacaat ctacggtaga tctgattaaa tccctatcta gctacaatcc aacagtttgg
    17461 acttatatgt ctagtattac taaaagtgtc atgcagcctc ttggagttgc gattttatca
    17521 gttgttctca tcttagaatt ttcgaagatg gcaaagaaga ttgctaactc tggtggagcg
    17581 atgacctttg aagcattagc gccgatgttg attagttata ttatggtcgc agtggtcatt
    17641 accaatacta ccgttatagt agaagctatc atcgggattg cgagtcacgc catcgaacaa
    17701 gtggcctcga ttgtggctca cggtggggcg aagtatgata cactctctgg attaaaaggt
    17761 tcaggattta ttggccggat gattgtgggc tttttcgctc tccttatctg gcttgttcgg
    17821 atagtaagtg cagccatggt taatcttttg gtatctattc gatttattca actctacctt
    17881 atgatcccat ttgcccctct tacgattcca acatttttaa gtgatgaatg gaagtctatt
    17941 ggtattggct atttaaaaaa tattatggtc tatgcggtac aaggggttct catttttctg
    18001 attgtttctc ttgttccttt gtttgaatct gctgggaaaa tagctgtttc aaatggtgca
    18061 ggagtcttgc aatcacttgc gattatgttt ggtagtttag tacaagctat cttactgatt
    18121 attgccctcg ttggttctca acgtacggct cgctcaatct taggtatgta attagataaa
    18181 ggctaggaag tgattgcttc ttagcctttt tagaaaggaa agtcatgaat acatgtgtct
    18241 ttaaagacat ctcaaaatac caacacaggg cttggttagg tttcaccaca agacaaatca
    18301 tctttgtttt accagccttt attgtcacaa ttattgtttt gggcttgaat ctctttttct
    18361 ggcaatttgg agattggttt gtttacggtt ttgtgtttgc ttttaccatc cccctaatgc
    18421 tttttggagt ctataaaccc aatgatttat attttgaaca ttatttgaaa taccgtcttc
    18481 attttgaatt aacggttccc ctacgcacaa ttacaggaaa gaaaggacct gaacatgaaa
    18541 agaaaatcaa atacattaaa gaaacaaaaa acttcaatga ctaataaaaa ggaagaagtt
    18601 aaagggaaaa aagaggaagt gttaccctca acggctaata ctctttccta tcaagccctg
    18661 tatcaaaatg gtctgatgca ggtaaaagaa gattatttct cacaaagcta tttacttggt
    18721 gatgtcaatt accagaccgt tggtttagaa gataagggcg caatcattga gaagtattct
    18781 gatttgatta actcactaga tgaccaaacc aacttccaat tgactatctt taataaaaga
    18841 ttgaatttag aaaagtttag acagagtgtt ctgtatgagg aaaaagaaga tgggtatgat
    18901 agctatcgta aagaattgaa tcggatgatg aatcagaatt tagacagtgg tgaaaataat
    18961 ttttcagctg tgaaactgat tagttttggt agaaaggatt ctaatcccaa acaagcctat
    19021 cgttccttgt ctcaaatagg cgaatatttc aagagtggtt tctcagaaat tgatgcacga
    19081 tttgaatcct tggctggaga agaacgggtg aacttgttgg ccgatatgct tagaggagaa
    19141 caccatcttc ctttttctta ccgtgattta acgagatcgg gtcagacaac tcgtcacttc
    19201 atagcaccta atctcttgga ttttaaaaac aagaattacc tacaaatcaa tgaccgttta
    19261 ttacagattg tctatgtgag agactacggt atggaattag gagatcagtt tatcagagac
    19321 ctcatgcaag gagatttgga attgattgta agcctccatg ctcaaagttc gaccaaggca
    19381 gatgccatga agaaactacg aacaaagaag accttgatgg aatcccaaaa gatcggggaa
    19441 caacaaaaac ttgctcgtac aggtatctat ttggaaaaag taggtcatgt attagaaagc
    19501 aatatcgatg aagctgagga actcttaaaa accatgaccg agacaggaga taaactattt
    19561 caaacagtct tcttgattgg tgtttttggt caggatgaag aagaactcaa acaagcacta
    19621 gacactattc aacaagtggc tggctcaaat gacctaatga ttgataaact accatatatg
    19681 caagaagcag cctttaatag tttgctacca tttggttgtg attttttaga gggagtatca
    19741 cggagtttat taacatctaa tgtagcagtg aactcacctt ggacttcagt agacttacaa
    19801 gaccgtagtg ggaaatatta cggtatcaat caaatatcaa gtaatattat taccattgat
    19861 cgcagcctat taaatacacc gtctggtctg attttaggaa catctggagc tgggaaaggg
    19921 atggcaacca agcatgaaat tatcacgacc aaaatcaagg aatctggtga aaatactgaa
    19981 attatcatcg tggatccaga agcagagtac agtgtcattg gacgaacttt tgggggagaa
    20041 atgattgata ttgcgcctga ttcccaaacc tatctcaatg tccttgactt gtctgaggaa
    20101 aatatggatg aggatcctgt aaaggtaaaa tcagaatttc ttttatcctt tatcggtaag
    20161 ttattggata gaaaaatgga tgggagagaa aaatcgatta tcgaccgagt tacgagactc
    20221 acttatcagt catttaaaga gccttctttg gaagaatggg tctttgtctt gagccaacaa
    20281 gcagaagaag aagcgcagaa tttggcactt gatatggaac tgtatgttga aggttctctt
    20341 gatatttttt ctcataagac caatattcaa acagggtcca atttcttaat ctataatgtt
    20401 aaaaagttag gagatgagct gaaacaaatt gcccttatgg ttgtttttga tcagatatgg
    20461 aatcgtgtcg ttcggaatca aaaattaggg aagaagacct ggatttattt cgatgagatg
    20521 cagcttctct tattagataa atatgccagt gatttcttct ttaaattgtg gagtcgtgtc
    20581 agaaaatatg gagccagtcc gactgggata acccaaaacg tcgaaacctt attgttagat
    20641 ccaaatggta gacggattat tgcaaatagt gaatttatga ttctcctcaa gcaagcaaaa
    20701 aatgatagag aagaattggt tcaactctta ggcttgtcaa aagaactcga aaaataccta
    20761 gtcaatccag aaaaaggggc tggactaata aaagctggtt cagttgtcgt tccctttaaa
    20821 aataagattc ctcaaggtac tcaattgttt gatatcatga gtacggatcc tgataaaatg
    20881 gcttctaatt aaggggaagg taaatgaagg ataaaagaga aatcatacgt gcccgaaagg
    20941 catttagaag aagtctaaaa gatgagaaga aattcttgaa aaaaggaaag aaggaggtaa
    21001 ggaaacagaa aaaagattcc gctgtactgg atgaaaaagc atggaaaaaa gagataaaag
    21061 aaaagctaga ggagatgaga gaagcttcaa aggctagagt aaaacaagca aatgaagact
    21121 acaatcacat ccttcaaaat actcctccat ctcttttgaa tcggaaagaa ttaagagaca
    21181 gacgattgcc tcatgctagg aaacgattga aaatagccaa gaagcaattt agagaagcca
    21241 aggtagaagc aaaagaagaa agaaaagaga gtcgtaaaga aagaaaaacc aatcaaaaat
    21301 ttctttatgg tcaggaatcg aaagcaaaat ccaatttttt ctttcaaggg aagagtttag
    21361 aagaattaaa agctaagaaa gaagtcaagg ccgcaaaaga taatctaaaa tctactaaac
    21421 aagcctataa gtccaaaaaa gtcagtagga aagccaaaac ttttctttat gtccttggac
    21481 gtgaaggtgg agagttagct tcagaaaatg aagatttaga aggctatcgt acacttcaag
    21541 agaccattag aaaagggaaa cgctacagtc gactttctta taatcttgga aaagctagtg
    21601 tcaaaacagg acaagcaaca ggtcgtttta ccaagaaaag actgaccaac acaaaagagc
    21661 gataccatca ttttaaggat ggaaaaggat ggaaactagc gaaagataat ccaagttcct
    21721 ttaaaaatcg gtatcgaaaa ttaaagaaac aaggtctttc aagtgtccga aatatctatc
    21781 aaaaactaaa agcagccttt tccttcttta catttacggc tgggaatcct gcaacctgga
    21841 tagttggagg attagtcttt cttctcttac ttatgatgag cttcttttta ggattttcat
    21901 ctgctagttt gattcaacaa gatgaatttg aattaacaaa agcttatacc catctaactt
    21961 gggaagatgc agaacatact cgcacaaatg acaaaggaat tacttattac acaaaagttg
    22021 atgatgtgat gggctatatg aactttaaat tccatgacta tgagttacac aaaccagttc
    22081 acttatttag ttcagaaact tacaaggatt atctgtctac tttgtggcat gatttaaacg
    22141 atggggatga tttgaaatcc atgcaagacc tctatgaaac tcctaagtat aaactctcga
    22201 aagacgatca agaggaaatg aaggaactaa aagaagaggg tgtatatgct tccatgcagg
    22261 aattggacaa tccatttgag gggaaaagca acgaagatag tctaaccatg acttatcgtt
    22321 atggatacta tgatttagat gggaaaccta ctcttcagga gtacattcta ctagaagcaa
    22381 aggctcacca aacgattgtc gcaccaatgg atggagttgt atctctagat ggtgacaata
    22441 ttattctcac taacggaaaa ggagagaatg agagtcgatt gaccttgtat tctattcata
    22501 atggccgtgc gattgagggg acaagagtct taacgggtga tattattggt gaaacaccag
    22561 acgatacagg tttgaaagtt tcctatcaaa agtataagaa caagaaagaa aaattggtgt
    22621 atgtcaatcc gcaattttat tttccaaaag tcattcaact tcagacaact atcttacctg
    22681 ccattggtca gtttggtggg gatgagtttg aacgagcaaa acatatttat gagtttttga
    22741 aatctcaagg ggcaagtccc caagccattg cggctatttt aggaaattgg tcggtagaat
    22801 cttctattaa tccaaaacga gctgaagggg attatttatc tcctcctgtt ggcgctaccg
    22861 attcctcatg ggatgatgaa acctggttag caattggagg tccagccatt tatagtggtg
    22921 cttatcctaa tatccttcat agaggtttgg ggttaggtca atggacggat actgcagatg
    22981 gttcaacacg gcatacagct ttattgaatt atgcacatat caaaaataag aagtggtatg
    23041 atttagatct ccaacttgat tttatgcttc atggggatag tccttactat caaagttggt
    23101 taaaggattt ctttggaaat acgggcagtg cagccaattt agcccaactc ttccttacct
    23161 attgggaggg aaattctggt gacaaactac tggaaagaca aaccagagca acagaatggt
    23221 attaccaaat tgaaaaaggc tttagccaaa caaacggagg acaggcaaag agtgatccac
    23281 aatccctcga aggtgttcgt ggggacttgt atgatcattc tgttcctggt ggtggagatg
    23341 gtatggccta tgcctatgga caatgtacat ggggtgttgc ggctcgtatg aatcagttag
    23401 gcttaaaatt aaaaggaagt aatggtgaga agatttcaat cattaatacc atgggaaatg
    23461 gtcaagactg ggttgcgaca gcttcaagtc ttggtgggga aactggctct acaccaagag
    23521 caggtgccat tgtttctttt gtaggaggta cacatggcac accagctatc tacggtcatg
    23581 tggcttttgt cgagaaagtc tatgatgatg gttctttcct tgtgtctgaa actaactatg
    23641 gtggcaaccc taactatacc tttagaaaaa tctcgcaagc agatagtgcc atcagttttg
    23701 cttatacggt gaaataaaag aatcatgtca tcagtttagg tgacatgatt cttatttttt
    23761 atagagtgac atatttaatg ccataggttg ataacttact tgatgatcgt ctttaatcaa
    23821 ttgactgtaa gcaacaaatc cgaactgttc ataaaattga atgactttag gatgattgat
    23881 actatctaaa aataccatct gagttcctac aattgctcga aattcttcaa ttttttgaat
    23941 tacaatttca aataactctt gtcctgatag tttatttagc tttgtgtttt tgccgaattg
    24001 accgataagt aacacaggga gataatcaat atttttggga ctttttcctt ttaggacgag
    24061 tttctttttt aaggattcct ttaaatcaga aatatcaaca actttgagag ataaactaaa
    24121 gaatcctatg atgttatttg tttcagtttc ttcaacgata aaattacgag aacgatgttg
    24181 tttttcaaaa ttgggagctt tatcagatag ataagtcaac atctcttcat tatctttgaa
    24241 attaacattt tctaaaatga tagttttaaa tagctcctga acttgtttct cagttttatc
    24301 aggagccagc acttgaatat tttcaagata ttgcttaagt ggtgttactt gaattgtcat
    24361 cttacagata ctttaaaatg agtttatttt tcgttggagc ggtagcgtct tgtgatttaa
    24421 tagatttcaa gactgcttgt agctttttag atggttcatg attaagaatt tttagagcat
    24481 cttcgtttgt tagttttata tcacgtgtta aactgattgt agccatttgt tctacctcct
    24541 gtttctactt aaattcatta tagcttattt tgaacaaaag ttcaatctaa agatagtgta
    24601 tgttttctat agtgtataaa tccaaaataa gtttttctct tgcgtttgta gctcatattc
    24661 gttagaataa tggtgtagat gagtggtcgg ctcatggtca atctgatagt aatcttggac
    24721 ataagggcca agcggtggcg gacaccagaa caaaatccga tagcaatctt ggacgtaatg
    24781 gccaagcggt ggcagacacc agaataaacc gactgactag gtggcttaca gattctgtaa
    24841 gtcatctttt tactttgata ataatgtttt atcattttaa ggagaacgca gttttggctc
    24901 gttctctttt ttgttgtgat acttctttca aggaatattt ggtaggattg gagtgaaaaa
    24961 agattaacta ggaaagaagg aagtatatgg aagccattta tcaacgtgat tcggatcaag
    25021 atggattaac tgatgctcaa gaattggcgc taggaaccaa tcctcttagc gcagattctg
    25081 atggtgatgg acgttcagat ttagtggaaa tagaagaagg aaccaatccc ttagaaaagg
    25141 atttacaaga catagaccaa acaagtatca ctgaaccgtc ctcagtatta atggaaatga
    25201 aacaaaagat ttcagatatg atggagagtc actacaagga atttatacag gctctgatta
    25261 gtattgaaac agggattgaa aaccaacaag acctagaaga cttatatact tactacatga
    25321 gaacggatgc cgtttctctt ttatctagtg atttagaaat cagtcctcaa gaggttgaaa
    25381 tggagataga gttgtagggg aatcatgtga ttctcctatt ttcgtataga tgaaaggagc
    25441 gagtatggaa gtaatacaat tattggctat gtttcgtgga acaattccaa aagatagaga
    25501 gaaaatggac ttatttcttc gttatcaagc gcaacatttt gatgagaaat ggcaggattt
    25561 ggtagagagt tttttgacta aagagggcaa aatagaagag atacctcatg tctattcgtt
    25621 tcatcaagat attgtttctt tcctagaggc cagttctgaa aataatgacc aagatttaga
    25681 aagttacaca agaaaatttg gacaagcagg tctaagtaaa ttatctcaat taagtaattt
    25741 tgagaaaaac ttggtgctag aagtcgcaac ctataacctt tccactcgat tttatatcca
    25801 atctgaaaaa gagaagctaa caccattaag tgagcttgta tttcatcaga atcaggatgt
    25861 caatttagtc aatgtctatc gggttgcgaa taatctatct gaccgtatta gtagagatat
    25921 agaggaattt cttctaatgg ttgattccaa agaactaaaa aaagaacttc ttgagattca
    25981 ttttgaagaa aaagagggag atgttctagc ctatttgggt tcagaattga tggctacttt
    26041 agataccgtt acggatcttg tccatcatga agaaaactac acacaactcc cactgacaca
    26101 aaagctgaag attattactc attttgatga agtgaaagct ataagagaaa agtctaatca
    26161 agtagaggaa tctttatctc cttcaagtga tattgaacag gaaacggaag aaacgaaccc
    26221 tttttctaat gtcgataaaa ttgtagaaga agctttgagg gaatatccaa ttggttcaca
    26281 agtaagttat aaaggacaag tatttcagtt ggtttcgatt gaaaatgctc agttaaatgg
    26341 cttagttcgc ctagagctat tcaatgattc caaccagtta tttgaagaga atcctatctt
    26401 atacttgaac agtttagaag agattgaacg agtattgtct catgtagaac ttgaaaaaga
    26461 agattcagag attgagatgg attcatcaag tgaaagtcag gaaatagatt tgttttccta
    26521 tctggaagaa gaaaaggaaa agtttaatga aacagaatca acaccactta tttcaagttt
    26581 agaagagttg gatattcctg ttcaagattt tgtttttcca gatgatttag agaactttta
    26641 tcctaagaca aatcgagaaa aaattgaaac gaatatcgcc gcaattgaac ttgttaaaag
    26701 attagaaaaa gagggacgac aagcgaatcc agaagaacaa gagctactag ccaagtatgt
    26761 cggctggggt ggtcttgcca atgaattttt cgatgaactc aatccaaagt atgaagcaga
    26821 acgtttaact cttaagagtt tagtaagtaa atcagaatac tccgccatga aacaaagttc
    26881 tctcacagcc tattatacag acccaatgat tattcgccag atttggcaaa aattactgga
    26941 tgatggtttt gagggaggga ggatattaga tccttctatg gggactggga acttctatgc
    27001 ggctatgcct agaaggatac gagagaaatc agaactctat ggggttgaat tagacagcgt
    27061 gacaggcgca atcgcaaaac aactccaccc caatacccat attgaagtgc gaggatttga
    27121 agaagtttcc tatcaaaata atagttttga tttagtctta acgaatgtcc catttggaaa
    27181 ttttcgcatt gcagataaaa actatgataa accttatatg attcatgatt actttgtcaa
    27241 acactcactt gatttagtaa gagatggagg acaagtttcg attatctctt ctattggcac
    27301 aatggataaa cggacagata atgtcttaca agagattaaa tccaacactc attttttagg
    27361 gggagttcgg ttgccagata cggcttttaa aagcattgca ggtactcgtg taaccacaga
    27421 tctcctcttc tttcaaaagg atcaagcaaa gaatcttaat gaagaggaac ttgtttttag
    27481 tggttctatt ccctttgagg aggataagcg tgtctggatc aatccttatt ttgatgggaa
    27541 atacaataca caagttttgg gtcaatatga ggtacgtaat tttaatggag gaaccctcaa
    27601 tgttaagggg gaatcagaaa cattagctac tgacataatg aaagcattag agaatgtaga
    27661 agctcctaaa caaattgaca attctttgaa agcacctgtt tttatccaag aagaagtgga
    27721 taattctatc ccaagtcgta tacgtgagga cttaacgctc tattcttttg gatatgaggg
    27781 aaatcaaatt tattaccgag atacgcatgg cattcggaaa agttcaaaag ttgacgaaat
    27841 tagttattat gtagatgaga agggagattt taaagcttgg gacagttctt tgtctgaaca
    27901 taaaatagac cgattcgtgc aacttcattt gactgatgag gaagcactag atgtttacaa
    27961 gtcagaagaa gcgagtaaaa gggggaaata taagggactg ttcaaaaaaa ctatctttta
    28021 tgaaagtccc ttatcggata aggatattag tcgcattaag ggcatggttg atttgagaga
    28081 gacctatcaa tccttaattg aaattcaacg tcatccagat tatagtcgga cagattttca
    28141 ggtattactt agtaaactca atcgtgacta taatcgcttt gtaagtcaat ttggatactt
    28201 gaatgcctca gtcaatcgga acttatttga tagtgacgat aagtattctt tattagcaag
    28261 tttagaagat gaatacattg attctaaaga tcagaaagta aaatataaaa aatctttagc
    28321 ctttgagaaa gcattggtta ggccggagag agtgattaca agagtatcaa cggctttaga
    28381 tgccttaaac tctagtttat cggatggtag aggggttgat ttagactata tggtatcaat
    28441 ttatcccgaa catagccaag ctgctatttt agatgagtta ggtgaccaga ttttaatgga
    28501 tccagaaagc tatttaagag gggaaagaaa atacctttct aagaaccagt ttttatcagg
    28561 agatattctc aacaagatag aagtagttca actattagtg gaggaaaaca accaagaata
    28621 tgattggaac catgctttag atttgttaga atctgttcgc cctccaagga ttcatctggc
    28681 agatattgag tttaaaatag ggtcacgttg gattcctcaa tccgtttatg gtaaatttgc
    28741 ctttgaatgt tttaccaatc gtgaatttga attgtcttcg ccagatgttg aacaagtcat
    28801 tgaagtgaat cctgtcgatg gccaggttca tttaaggaca tcatttgctt atcgctatcc
    28861 aagtgccaaa gatagtagtc ttggagttag tgggtcacgt tatgatacag gaagaaagat
    28921 ttttgagaat ttacttaatt cgaaccaacc gacgattacc atgactgtta cggaaggaga
    28981 aaagaaaaag accatcacag atttggaaaa aacctctgtt ctaagagcaa aagagcagca
    29041 tttacaagag ctctttcaag aatttgtctc acagtatcca gaagtccaac aagtcattga
    29101 agaaagttac aatcgtcttt ataatcggac ggttagtcga gagtatgatg gtagccatct
    29161 agtcattgat ggcttggcac aaaacatcag tcttcgtcct caccaagaga atgccattca
    29221 aagaattata gaagaaaaaa gagccttatt agctcatgag gtaggttcag gaaagacctt
    29281 gaccatgctt ggtgctgggt ttaaattaaa ggagttgggg atggttcata agcccttgta
    29341 tgtggtgccc tctagtttgt ctgctcagtt tggccaagaa atcatgaaat ttttccctac
    29401 taaaaaagtc tttgtgacca ctaagaaaga ttttgtgaag gcgagaagaa aacaatttgt
    29461 ttctcgtatt attacaggag attacgatgc cattgtcatt ggggattctc aatttgaaaa
    29521 aatccctgtc agtaaggaaa gacagatgaa ctatatagag gataaactca atgaactacg
    29581 agagattaaa acacattctg aaaataagta taccgttaaa gaagcagagc aatcaataag
    29641 tggtctagag aaacaattgg aagaactcca acgctttaat cgtgatagtt ttattgattt
    29701 tgagaactta ggaattgatt ttctctttgt ggatgaagca catcacttta aaaatattcg
    29761 tccaattact ggacttggaa atgtagcagg gattaccaat acaacctcta agaagaacgt
    29821 ggatatggaa atgaaggttc gacagattca ggaagaacat gattataaaa atattgtctt
    29881 tgcgacagga acacctgttt ccaattctat tagtgagtta tatactatga tgaactatat
    29941 tcaaccagat attttaaaac gctatcaagt tgattatttt gactcttggg taggtgcttt
    30001 tggagaaatt caaaactcta tggaattagc tcctacaggg gataagtacc aacctaagaa
    30061 acgattcaaa aagtttgtca atctacctga gttgatgaaa atctataaag aaacagccga
    30121 cattcaaaca caagatatgt tggatttacc tgttccagaa gctcatatta tccctattga
    30181 gagtgagtta actgaaaacc agaaactcta tttagaagaa ttggttatga ggtcagatat
    30241 ggtcaaatgt ggaacagttg atccgagcca ggataacatg ttaaagataa caggtgaggc
    30301 acgaaaacta gcaattgata tgcgtttatt ggactctagt tatagtctag cagacaatca
    30361 taaattgctt caggtagtgg ataatgttga aagaatttat cgtgagggaa tggaaaataa
    30421 ggctactcag atgatttttt cagatattgg aacacctaag aagaaggaca atggctttga
    30481 tgtttattct gagattaagg ctttattagt tgatagagga gtccctagta aggaaattgc
    30541 ctttgtacat gatgccaata gtgatgaaaa gaagaatagc ttgtctcgaa aggtcaatgc
    30601 aggagaggtg cggattcttc ttgcctcaac tgaaaaagga ggaacaggtt taaatgttca
    30661 gagcaagatg aaagcagttc atcatctgga tgtaccgtgg agaccaagtg acattcagca
    30721 acgcaatgga cggattatcc gacaaggaaa tgaaaacaag gaagtggata tttaccacta
    30781 tattaccaaa ggttcgtttg ataattatct atgggcaact caggagaaca aactccgtta
    30841 tattaagcag attatgactt ctaaggagcc gattcgtgct gcagaagaca ttgatgagca
    30901 gaccatgaca gcttctgatt ttaaggcact agcaacaggt aatccttatc tcaaatataa
    30961 gatggaacta gagaatgatc taaccctatt agaaaatcaa agacgcgcct ttcaacgtag
    31021 caaggatcac tatcgtcata caatctctta ctgtgaagaa aatattccca ttcttgagaa
    31081 acgattaagc aagtatgaag gcgacattca acagtctgaa atgtcgaaag accaatcatt
    31141 ttctatgacg gtaggcaagc aagcttttga gcaacgagct gaagcagggg aatccctaca
    31201 ccgtcttatc cgtcataatc aagctgatat taaagaatta cgtaccctag ccagttatcg
    31261 aggatttgac attaaaatgc ttagtcttcc aacaaatcaa cctcttcctg aaactttctc
    31321 tgttaagatt gtaggagaaa atcggtattc tgtcagttta gatttgtatt ctcctttggg
    31381 gacaattcaa agactccaac atacgataga ccacattaaa gatgaccaag tgaaaactca
    31441 gaacttattg gatgaattaa aggataaatg gactactgct aagatagaaa ttgagaaaaa
    31501 ttttccaaag gaagaggatt atcaaactaa aaaggccgaa tacgatgtac tcgcgccatt
    31561 gattgaaaca gaaacggatt tagatattat tgatcaggcc ttacgacaat tccacgaaaa
    31621 aggaaaagaa aagcaagaac aactttcttt tgaattggat taaaaaatag atataaatag
    31681 cggacaagaa aagaaaagcg cggtagaata aagatagaaa gaaacgaggt aacgattatg
    31741 atggaagata cctattatca attagaagag gctttggtac agggatttca aacacctgaa
    31801 gaataccaag cctacaagga gttaaaggaa cattatgagg aagtgacagg cgattacagc
    31861 ttttctatac gagaacttac tagtcaattg gaaatcgctc ttcagaatca tcgaggtgtg
    31921 gactttgaag aacatgagaa agaggagtat ttggacttag ttcaaaaatt agaagagttt
    31981 gattcctctc ttgccaccca ttatcgtcaa ttgattgact agaaaggaga aagtcatgaa
    32041 tgatttactc cttatcccag taattttttt agcagtagga ggaattctca ttcttttatg
    32101 gagactcttt cttattgcca gtggactttt ccttattggt tttatcagtt ttcttatttt
    32161 cgtggaggtc tatggaattt atctgttctt tactgaaccg actttatact tcgatgatat
    32221 cagacaacat ggtttaacta gttttacggc tgtgtacctt ttcatcaatc tgatgttggt
    32281 tctaggattc agttggcgtt taataaactc caaaactaag gaaagtatgt aaacttgtta
    32341 gatggttaaa aaactttatc tgaatctaaa ttcggataag gttttttatt agccttgatt
    32401 ctttcatata cttcatagct aaattggagc agtaatttat gaaaatcatt atcctcactg
    32461 ttattacttg tatttatggc ttgtctatgt cgttcaatat gagaaagagc tcttctcaaa
    32521 ttttcttctt ttaaattttt catagttaca ttataagctg aagacagata gttttgatat
    32581 ttttctctga actgtacgat tttgcttctt aaatgtagga atcacctttt attatggtgt
    32641 gataaaactt acaagtcctt tttgttattc ttgacctagt ttttatagaa agaaggtcta
    32701 agatgttaaa taaagtcaaa actaaagcct taattagtgt tggagcagtg gctgcaacta
    32761 gctttattct catgatggga tatactgctg gtcaacactc gactgctaaa caaagtcgta
    32821 aagagattga attggctgca gctaaacttg tagagaataa acaagcagaa gataaagcca
    32881 gcattttgtc atcggatact gtaaaagaat ttttgacgca gtactatacg aaagaaaagc
    32941 tcggagaaaa taatacacgt attcaacctt atatgactga atcggcttat tctcaagaat
    33001 tgtcaagtca aaatgatgcc atgaaccaag tgtataagga ttatatttta gattatcatt
    33061 ttgaaaaagc tgatatcttt gtcaatcaga ctacgaatca agccattgcc atggtctcat
    33121 ataatgtaac ctatgtatcc gatttaaaga atgcaaacca atcaaagacc aatcagacag
    33181 aaaccagaac ggttaaattg tcctattcta aactacctgg taagttattg gtcaatcaag
    33241 tacaggtttg gaaatctgga ttagatgatt tagataaggc cactcccaaa actttagaag
    33301 aatcatcatc aataccatca ctgccaaata ctacgacaaa atgatgatat tgcatggaaa
    33361 tagaagaatg taggcaaatt tcaattcttg atgtagcaag tcgtttaggt atctccttta
    33421 aacaagtttc gaccagtgtc tatgagcatt ctgaacacga ttcatttcgg attttttcaa
    33481 ctaccaatac ttttaaatgg ttttcaagag atattcaagg tgatgtcatt gattttgttc
    33541 gacttgttaa gggaatttcc tttaaagaag ctctagcctt tctttctgaa gaaccttttc
    33601 aaaaagaagc tgttcaagaa aaaagagaga gaccatttta ttatccttta aagagagtag
    33661 aagattctaa ctgcagtctg gctagatatt atttaacaga atgtagagga atctcagaag
    33721 aaatcataca aaagatgatt caacaaggtt tgatagccca agctagttgg aaaacaaatg
    33781 aaacagttga acctgttatc gtttttaaaa gctatgatca tcgtcacaag ctgcaggcag
    33841 caagcttaca agggatttat aagaatcact ctcttcctag agagaggctg aaaacgattc
    33901 taaaaggaag ccatggacat attggaatat cttttgatat tggtaaacca aatagactgg
    33961 ttttttgtga atcgttcgtc gacttgataa gctattacga acttcatcaa caaagtctaa
    34021 ctgatgttcg tttggtatct atggaaggat taaaaaggtc tgttgttgct tatcaaactt
    34081 tacgactaat agctgaagaa aatcagaagt tggaattttt agatacagta acaccttcaa
    34141 agttattgca tttgatcaat acaattcgtg ataccaccac ctatttcgat aatcatcctg
    34201 atttattgac acttgcggta gattgtgatg atgcaggaaa agatttttct gataagttat
    34261 ctcaatcagg atttcctgtt ttactggatt tacctaataa tgaatctggg aaagaaaaaa
    34321 tagactggaa cgatattctt agagaaaaga aatcagattt acaattgatg atcgagaatg
    34381 taaaagagac attgaggaat caaccagtaa gacaaacctc tcaatgttta gaattgtgat
    34441 aacaaaatca agatgtttta gctaatatta gaatgaagga ggatcgtata tgaccataat
    34501 cgagcgctta gaagaaaagg tcactaggca agaaagcaag gtagcaagag agacagaaaa
    34561 actagctgct tacagagagc aactggagac agcgatgttt gcgacgttca aaaggcgtca
    34621 aagcatcagt cacatgagtt ttgaagaagc tcttgaccat gcctttggta aagaaagaca
    34681 attcgatgat tctgaattta gaaaggatga aatgagtgaa tgacaaaaga ttggaatttt
    34741 aatcaaccat tagaaagtaa atcagaaaat caagaagatc cagataaaat tgcggcctta
    34801 tttggaaatc atcaaggagg taatgatgta aattatgaag cagcttttca aaagagaaaa
    34861 caagcacctg tgacagaatc aaattctagt tctaaaccca aagttacaga ggttagaaca
    34921 ggaaaagaaa cagatatcac tacaagttat cagcaacatc ttaaaagact gattgcggat
    34981 aacaatagcg atattcaaag cagtcagaag aaaattgaag agctacatac gttaattgac
    35041 acaaagaata aagataataa gaaattgcag tcaatttatg atgcgatttc agaattacat
    35101 taagcagtcc taagaggctg ctttttttga gaggctatag atgtttacaa aactttttaa
    35161 gaagaatcaa gacaatagtg atatatttaa gaagctaatt catcgactat ctgatatgtc
    35221 cgttcaagat cttgaaaaaa tagaccgact gctagatatc attttcactc cagatcaagg
    35281 atcagaacaa ctaaaaacag aatcaactta tagagaagaa actttggacg acacattaaa
    35341 ggaagcaaag aatcaacttc ataaggaaca attggaaaag aatttagaga gatttaggaa
    35401 aaatagccaa taatgcacca aaaatggtgc atttactttt tctaaatgtt ataatggtgg
    35461 tataaaaata aaaggagttt gccatgattg gaaagaacat aaaatcctta cgtaaaacac
    35521 atgacttaac acaagacgac tttgcccgaa ttgtaggaat ttctcgaaat agcttgagcc
    35581 ggtatgaaaa tggaacgagt tcagtctcta cggaactaat agacatcatt tgtcagaagt
    35641 ttaatgtatc ttatgtcgat attgtaggag aagataaaat gcttaatcct gttgaagatt
    35701 atgaattgac tttaaaaatt gaaattgtga aagaaagagg tgctaatcta ctatctcgac
    35761 tctatcgtta tcaagatagt cagggaatta gcattgatga tgaatctaat ccttggattt
    35821 taatgagtga tgatctatct gacttgattc atacgaatat ctatttagta gaaacttttg
    35881 atgaaataga gaggtatagc ggctatttgg atggaattga acgtatgtta gagatatctg
    35941 aaaaacggat ggtagcctaa tgggaatcca agattatacc gatagtgaat tcaaacaggc
    36001 tttagagcga aaccttcgct ctctgacaag aggaaaaaag tccagtaagc aacctatagc
    36061 gattttgctt ggagggcaaa gtggtgctgg aaagactaca attcatcgta ttaaacagaa
    36121 agagtttcaa ggaaatattg ttatcataga tggcgatagt tttcgttctc agcatccaca
    36181 ctatttagaa cttcagcaag aatatggcaa agatagtgtt gaatacacca aggattttgc
    36241 aaggaaaatg gtagaatctt tagtaacaga attgagtcat ttgggataca atcttttgat
    36301 agagggaact ttacgaacga ttgatgttcc aaagaaaaca gcacaactct tgaaaagtag
    36361 gggatatgaa gtacaattag ccttgattgc gacaaagcct aagctgtcct atctgagcac
    36421 ccttatccga tacgaagaac tatacgctat caatccaaat caagcacgtg caactccaaa
    36481 agaacatcat gatttcattg taaatcatct agttgataat acacgacaat tagaaaaact
    36541 agctatcttt gaaagaattc aaatttacca acgagataga agttgtgtat atgattcaaa
    36601 agaaaataca acttcagcag cagaagtgct acaagaatgc ctcttcggaa aatggagcaa
    36661 ggtagaggaa gagatgttga aggtgggaga agagatttta gaaaccttgt gtaatcgtac
    36721 agaataatga tgaagaaaaa atattaggaa gtgaa
//
LOCUS       DAVLTG010000016        36472 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLTG010000016 DAVLTG010000000
VERSION     DAVLTG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.016"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            76..213
                     /locus_tag="VYN12_000847"
     CDS             76..213
                     /locus_tag="VYN12_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1415261.1"
                     /translation="MDFEYFYNREAKRFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     K"
     gene            220..654
                     /locus_tag="VYN12_000848"
     CDS             220..654
                     /locus_tag="VYN12_000848"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1415262.1"
                     /translation="MSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDIK
                     KGIGLIERVRLGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQ
                     EVKNLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDI"
     gene            complement(712..1516)
                     /locus_tag="VYN12_000849"
     CDS             complement(join(712..1146,1148..1516))
                     /locus_tag="VYN12_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1415263.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTIMIDVTEVKINRPKKELANYSGKKKCYAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKFKPLTVEDKTYNHA
                     LSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            1511..1765
                     /locus_tag="VYN12_000850"
     CDS             1511..1765
                     /locus_tag="VYN12_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1415264.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            2060..3394
                     /gene="trmFO"
                     /locus_tag="VYN12_000851"
     CDS             2060..3394
                     /gene="trmFO"
                     /locus_tag="VYN12_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1415265.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            3478..4215
                     /locus_tag="VYN12_000852"
     CDS             3478..4215
                     /locus_tag="VYN12_000852"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1415266.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            4224..4781
                     /gene="frr"
                     /locus_tag="VYN12_000853"
     CDS             4224..4781
                     /gene="frr"
                     /locus_tag="VYN12_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1415267.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            4841..5695
                     /gene="cvfB"
                     /locus_tag="VYN12_000854"
     CDS             4841..5695
                     /gene="cvfB"
                     /locus_tag="VYN12_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1415268.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            5704..5919
                     /locus_tag="VYN12_000855"
     CDS             5704..5919
                     /locus_tag="VYN12_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1415269.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            6005..6973
                     /locus_tag="VYN12_000856"
     CDS             6005..6973
                     /locus_tag="VYN12_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1415270.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(6951..7130)
                     /locus_tag="VYN12_000857"
     CDS             complement(6951..7130)
                     /locus_tag="VYN12_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415271.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            7166..7667
                     /locus_tag="VYN12_000858"
                     /pseudo
     CDS             7166..7667
                     /locus_tag="VYN12_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            7670..7929
                     /locus_tag="VYN12_000859"
                     /pseudo
     CDS             7670..7929
                     /locus_tag="VYN12_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(8296..8622)
                     /locus_tag="VYN12_000860"
     CDS             complement(8296..8622)
                     /locus_tag="VYN12_000860"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415272.1"
                     /translation="MVDIAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(8568..8981)
                     /locus_tag="VYN12_000861"
     CDS             complement(8568..8981)
                     /locus_tag="VYN12_000861"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV1415273.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(8982..9407)
                     /locus_tag="VYN12_000862"
     CDS             complement(8982..9407)
                     /locus_tag="VYN12_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV1415274.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            9584..10153
                     /locus_tag="VYN12_000863"
     CDS             9584..10153
                     /locus_tag="VYN12_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415275.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            10221..10871
                     /locus_tag="VYN12_000864"
     CDS             10221..10871
                     /locus_tag="VYN12_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1415276.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            10855..13095
                     /locus_tag="VYN12_000865"
     CDS             10855..13095
                     /locus_tag="VYN12_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1415277.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            13274..13462
                     /locus_tag="VYN12_000866"
     CDS             13274..13462
                     /locus_tag="VYN12_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415278.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            13495..14082
                     /locus_tag="VYN12_000867"
     CDS             13495..14082
                     /locus_tag="VYN12_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415279.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            14086..15270
                     /locus_tag="VYN12_000868"
     CDS             14086..15270
                     /locus_tag="VYN12_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415280.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     misc_feature    15434..15565
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            15581..16111
                     /gene="infC"
                     /locus_tag="VYN12_000869"
     CDS             15581..16111
                     /gene="infC"
                     /locus_tag="VYN12_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1415281.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            16144..16344
                     /gene="rpmI"
                     /locus_tag="VYN12_000870"
     CDS             16144..16344
                     /gene="rpmI"
                     /locus_tag="VYN12_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1415282.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            16396..16755
                     /gene="rplT"
                     /locus_tag="VYN12_000871"
     CDS             16396..16755
                     /gene="rplT"
                     /locus_tag="VYN12_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1415283.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            16813..17193
                     /locus_tag="VYN12_000872"
     CDS             16813..17193
                     /locus_tag="VYN12_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1415284.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            17443..18243
                     /locus_tag="VYN12_000873"
     CDS             17443..18243
                     /locus_tag="VYN12_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1415285.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            18206..19192
                     /locus_tag="VYN12_000874"
     CDS             18206..19192
                     /locus_tag="VYN12_000874"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1415286.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            19234..21267
                     /locus_tag="VYN12_000875"
     CDS             19234..21267
                     /locus_tag="VYN12_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV1415287.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMTSD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(21328..22983)
                     /gene="pavA"
                     /locus_tag="VYN12_000876"
     CDS             complement(21328..22983)
                     /gene="pavA"
                     /locus_tag="VYN12_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1415288.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            23088..23585
                     /gene="ybeY"
                     /locus_tag="VYN12_000877"
     CDS             23088..23585
                     /gene="ybeY"
                     /locus_tag="VYN12_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1415289.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            23566..23961
                     /locus_tag="VYN12_000878"
     CDS             23566..23961
                     /locus_tag="VYN12_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1415290.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            23978..24877
                     /gene="era"
                     /locus_tag="VYN12_000879"
     CDS             23978..24877
                     /gene="era"
                     /locus_tag="VYN12_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1415291.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            24925..25749
                     /gene="mutM"
                     /locus_tag="VYN12_000880"
     CDS             24925..25749
                     /gene="mutM"
                     /locus_tag="VYN12_000880"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1415292.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            25749..26354
                     /locus_tag="VYN12_000881"
     CDS             25749..26354
                     /locus_tag="VYN12_000881"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1415293.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEAIVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            26341..27540
                     /locus_tag="VYN12_000882"
     CDS             26341..27540
                     /locus_tag="VYN12_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1415294.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRIFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            27540..27689
                     /gene="rpmG"
                     /locus_tag="VYN12_000883"
     CDS             27540..27689
                     /gene="rpmG"
                     /locus_tag="VYN12_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1415295.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            27729..27962
                     /gene="secG"
                     /locus_tag="VYN12_000884"
     CDS             27729..27962
                     /gene="secG"
                     /locus_tag="VYN12_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1415296.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            28064..30418
                     /gene="rnr"
                     /locus_tag="VYN12_000885"
     CDS             28064..30418
                     /gene="rnr"
                     /locus_tag="VYN12_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1415297.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            30381..30848
                     /gene="smpB"
                     /locus_tag="VYN12_000886"
     CDS             30381..30848
                     /gene="smpB"
                     /locus_tag="VYN12_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1415298.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            30864..31724
                     /gene="tehB"
                     /locus_tag="VYN12_000887"
     CDS             30864..31724
                     /gene="tehB"
                     /locus_tag="VYN12_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1415299.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            31797..32750
                     /gene="coiA"
                     /locus_tag="VYN12_000888"
     CDS             31797..32750
                     /gene="coiA"
                     /locus_tag="VYN12_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1415300.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            32769..34571
                     /gene="pepF"
                     /locus_tag="VYN12_000889"
     CDS             32769..34571
                     /gene="pepF"
                     /locus_tag="VYN12_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1415301.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            34573..35286
                     /locus_tag="VYN12_000890"
     CDS             34573..35286
                     /locus_tag="VYN12_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1415302.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            35353..36294
                     /gene="prsA"
                     /locus_tag="VYN12_000891"
     CDS             35353..36294
                     /gene="prsA"
                     /locus_tag="VYN12_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1415303.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
BASE COUNT        11023 a         6765 c         8178 g        10506 t
ORIGIN      
        1 atggttacca aaggcgatag aagaaaaact atcgtctttt tctttgcaaa tttttaagaa
       61 gggaggtgat cttgcatgga ctttgaatat ttttataaca gagaagcgaa aagatttaac
      121 ttcttaaaag taccggagat attagttgat agagaagaat ttcggggctt atcagcagaa
      181 gcaattatcc tttattccat acttcttaaa tagacaggaa tgtcatttaa gaataactgg
      241 atagacaagg aaggcagagt atttatctat tttactgtcg aagaaattat gaaaagaaga
      301 aatatctcaa agccaactgc cataaaaaca ttagatgagc ttgatataaa aaaaggaata
      361 ggactgatcg aaagagtaag gcttggactt ggtaagccga acatcattta tgttaaagac
      421 tttatgagta tatttcaggt aaaagaaaat gacttacaga agtcaaaaaa cttaacttca
      481 gaagtaaaag attttaacct cagaagtaaa gaaaatgaac ttcaagaggt taagaacctt
      541 gactctaact atatagagaa taataagagt aagtatagta agagagaata tagttttggt
      601 gaaaacggac ttggaacatt tcaaaatgtg tttttagctg ctgaagatat ataggattta
      661 caaatcataa tgaactcaca gcttgagaat tacattagac ttcctgcaaa actagaatcc
      721 tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaatc gtttacgatg
      781 atttcgatag gttgttgaaa acattttaaa cgtttctact ttggcaaaga tgttctcaac
      841 cttgcttctc tccttagata gcgcatggtt ataggtttta tcttcaactg ttagcggctt
      901 gaatttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata
      961 accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca ttttgaacaa
     1021 cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt
     1081 gacaatcgct tgagccttca tagcgtagca tttcttttta ccagaataat tcgctaattc
     1141 tttttttagg gcgattgatt tttacttccg tcacatcaat cattatcgtg tcctcagaac
     1201 tgagaggagt tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc
     1261 tccgacggat taagttgctt tcgtgaatac caaaatcagc cgcaatttgc tcataagttc
     1321 gatattctcg cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt
     1381 ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt taatacagct aatatctctt
     1441 caaaagtcgt gcgctgaaca ccaacaagac gcttaaatcg tgcatcagtt agttgtttac
     1501 ttgcttcatc attcatagaa ctactatacc atattttgtt tcgcaggaag tctattggaa
     1561 agtaagaaat attgaagctg aggcgattag aagaaattgt gagcgtggtg ctattttttc
     1621 aggtaaaata aaacatcacg aagattctca gtttaaagga gaccactatg ttgaatgtta
     1681 tgctgtttta gataatacgg ttatagcaag agatagaata acagtcccta tcgatccgtt
     1741 atgtggaaaa gattttatag agtagcatat aattgattct taactggaat actctctatc
     1801 tctttacatc aagaaaatga ctaaacaggg aagtttgcct tcttcccttt ttttgttata
     1861 ctagtagaag aaaaaaatag aaagatttgt gggagtgaaa aagtccgggg gactttttca
     1921 gcttgagcca agaaattcga gagcgaggaa agtctggggg actttttcag cctgagccaa
     1981 gaaactcgaa atctcgtaag tctgattggc tttttcaatg tgaatcttaa cttcacactc
     2041 ccaaagaggt attagtgtcg tgtctcaatc ttatatcaat gttatcggtg ctggtttggc
     2101 aggttctgaa gcagcttacc aaatcgcaga gcgtggtatt ccagttaaac tttatgaaat
     2161 gcgtggtgtc aagtctacac cccagcataa aacagacaat tttgctgagt tggtttgttc
     2221 caattctttg cgtggggatg ctttgacaaa tgcagttggt cttctcaagg aagaaatgcg
     2281 tcgcttgggt tctgttatct tggaatctgc tgaggctaca cgtgttcctg ccggtggagc
     2341 ccttgcggtg gatcgtgatg gtttctctca aatggtgacc gaaaaagtgg tcaaccaccc
     2401 cttgattgaa gtggtgcgtg atgaaattac agaattgcca acagatgtta ttacagttgt
     2461 ggcgactggt cccttgacta gcgatgccct ggctgaaaag attcatgccc ttaataatgg
     2521 cgatggcttc tatttctacg atgcagcagc gcctattatc gatgtcaaca ctatcgatat
     2581 gagtaaggtc tatctcaaat ctcgttatga taagggagaa gcagcctatc tcaatgctcc
     2641 aatgaccaag caagagttta tggatttcca tgaagccttg gtcaatgcgg aagaagcacc
     2701 gctcaattct tttgaaaaag aaaagtactt tgaaggatgt atgccaatcg aagttatggc
     2761 caaacgtggc attaaaacta tgctttatgg ccctatgaag ccagtcggtc ttgagtatcc
     2821 ggacgactac acaggacctc gtgatggaga atttaaaaca ccttatgcgg ttgtgcaact
     2881 tcgtcaggat aatgcagctg gtagcctata caatattgtt ggtttccaga cccacctcaa
     2941 atggggagaa caaaagcgtg tcttccaaat gattccgggt cttgaaaatg cggagtttgt
     3001 ccgttatggt gtcatgcatc gcaattctta catggattca ccaaatcttc ttgagcagac
     3061 ttaccgttcc aagaaacaac caaatctctt ctttgctggt cagatgacgg gggtggaagg
     3121 ctatgttgag tcggcggctt cgggcttagt tgcgggaatt aacgcagctc gtctcttcaa
     3181 ggaagaaagc gaggttattt tccccgagac gacagcgatt ggaagcttag ctcattacat
     3241 tacccatgcc gacagcaaac atttccaacc aatgaatgtc aattttggga tcatcaagga
     3301 gttggaaggc gagcgtatcc gtgataagaa ggctcgttat gaaaaaattg cagagcgtgc
     3361 ccttgccgac ttagaggaat ttttgactgt ctaatttttt tgaaagaatt gttcatgata
     3421 ctataaaaat cttagaaatt gtgataaaat aggtaggatg aaagaaggag agtgaaaatg
     3481 gcgaatccca agtataaacg tattttaatc aagttatcag gtgaagccct tgccggtgaa
     3541 cgtggcgtag ggattgatat ccaaacagtt caaacaatcg caaaagagat tcaagaagtt
     3601 catagcttag gtatcgaaat tgcccttgtt attggtggag gaaatctctg gcgtggagaa
     3661 cctgcagcag aagcaggtat ggaccgtgtt caggcagatt acactggaat gcttgggact
     3721 gttatgaatg ctcttgtgat ggcagattca ttgcaacaag ttggggttga tacgcgtgta
     3781 caaacagcta ttgctatgca acaagtggca gagccttatg tccgtggacg tgcccttcgt
     3841 caccttgaaa aaggccgtat cgttatcttt ggtgctggaa ttggttcacc atacttctcg
     3901 acagatacaa cagcggccct tcgtgcagct gaaatcgaag cagatgccat cctcatggct
     3961 aaaaatggcg tcgatggtgt gtacaatgcc gatcctaaga aggacaagac agccgttaag
     4021 tttgaagaat tgacccaccg tgatgttatc aacaaaggtc ttcgtatcat ggactcaaca
     4081 gcctcaaccc tctcaatgga caacgacatt gacttggttg tcttcaacat gaaccaatca
     4141 ggcaacatca aacgtgttgt atttggtgaa aatatcggaa caacagtttc aaataatatc
     4201 gaagaaaagg aataagaaag aatatggcta acgtaattat tgaaaaagct aaagagagaa
     4261 tgacccagtc tcaccaatca cttgctcgtg aatttggtgg tatccgtgct ggtcgtgcca
     4321 atgcaagctt gcttgaccgt gtacatgtag aatactatgg agtcgaaact cctcttaacc
     4381 aaatcgcttc aattacgatt ccagaagcgc gtgttttgtt ggtaacacca tttgacaagt
     4441 cttcattgaa agacatcgaa cgtgccttga acgcttctga tcttggtatc acaccggcta
     4501 atgacggttc tgtgattcgc ttggttatcc cagctcttac agaagaaact cgtcgtgacc
     4561 ttgctaaaga agtgaagaag gtcggcgaaa atgctaaagt ggctgtccgc aatatccgtc
     4621 gcgatgctat ggacgaagct aagaagcaag aaaaagcaaa agaaatcact gaagacgaat
     4681 tgaagactct tgaaaaagat attcaaaaag taacagacga tgctgttaaa cacatcgacg
     4741 acatgactgc taacaaagag aaagaacttt tggaagtcta aaaataaaca gaaaaactca
     4801 gttggcattg ctggctgagt tttattcgaa agaaggaaat atgaatacaa atcttgcaag
     4861 ttttatcgtt ggactgatca tcgatgaaaa tgaccgtttt tactttgtgc aaaaggatgg
     4921 tcaaacctat gctcttgcta aggaagaggg ccaacataca gtaggggata cggtcaaagg
     4981 ttttgcatac acggatatga agcaaaaact ccgcctgaca accttagaag tgactgccac
     5041 tcaggaccaa tttggttggg gacgtgtcac agaggttcgt aaggacttgg gtgtctttgt
     5101 ggatacaggc cttcctgaca aggaaatcgt tgtgtcactc gatattctcc ctgtgctcaa
     5161 ggaactctgg cctaagaagg gcgaccaact ctacatccgt cttgaagtgg ataagaaaga
     5221 ccgtatctgg ggcctcttgg cttatcaaga agacttccaa cgtctcgctc gtcctgccta
     5281 caacaacatg cagaaccaaa actggccagc cattgtttac cgtctcaagc tgtcaggaac
     5341 ttttgtttac ctaccagaaa ataatatgct tggttttatt catcctagcg agcgttacgc
     5401 agagccacgt ttggggcaag tattagatgc gcgcgttatt ggtttccgtg aagtggaccg
     5461 cactctgaac ctctccctca aaccacgctc ctttgaaatg ttggaaaacg atgctcagat
     5521 gattttgact tatttggaaa gcaatggcgg tttcatgacc ttaaatgaca agtcatctcc
     5581 agacgacatc aaggcaacct ttggcatttc taaaggtcag ttcaagaaag ctttaggtgg
     5641 tcttatgaag gctggtaaaa tcaagcaaga ccagtttggg acagagttga tttagggagg
     5701 cttatgagaa aatcatttta cacttggctc atgaccgagc gcaatcctaa aagtaacagt
     5761 cccaaagcaa ttttggcaga cctcgctttt gaagagtcag cctttccaaa acatacagat
     5821 gattttgatg aggtcagtcg ctttttggag gagcatgcca gtttctcttt taacctagga
     5881 gattttgaca gcatttggca ggaatatcta gaacactagc atttattcat tgggtttggg
     5941 ctagtaattt ctccatccct ctgctataat aaaaagaaat aaaaggatta gagaggttct
     6001 ttatttgaag gaacattcaa tagacattca actgagtcat ccagatgacc tgtttcatct
     6061 ttttggttcc aatgaacgcc atcttcgttt gatggaagaa gagcttgatg ttgtgattca
     6121 tgctcgtacg gagattgtcc aggttttggg agaagagtct gcctgtgagg aagcccgtca
     6181 agttattcag gctttgatgg tcttggtaaa tcgtgggatg accgttggta cgccagatgt
     6241 agtcactgcg attagcatgg tcaaaaatga tgaaattgac aagtttgtcg ccctttacga
     6301 agaagaaatc atcaaagaca atactgggaa gcctatccga gtcaaaacct tgggtcaaaa
     6361 actttatgtg gacagtgtca aacagcatga tgtgaccttt ggaatcggac ctgcagggac
     6421 agggaagacc ttccttgcag tgaccttggc agtgactgcc cttaaacgtg ggcaagtcaa
     6481 acgaattatc ctgacacgcc cagcggtgga agcaggagag agtctaggtt ttcttccggg
     6541 tgatcttaag gagaaggtgg atccttacct tcgtcctgtt tacgatgcct tgtatcaaat
     6601 tcttgggaaa gaccaaacga ctcgtctcat ggagcgtgaa attatcgaaa ttgcgcccct
     6661 tgcctatatg cgtggccgga ccttggatga tgcctttgtc attctcgatg aggcgcaaaa
     6721 cacgaccatc atgcagatga agatgttctt gacgcgttta ggctttcatt ctaagatgat
     6781 tgtcaatgga gatatcagtc agattgacct gccacgtaat gtcaagtccg gtttgattga
     6841 tgctcaagag aaactcaaga acatccatca gattgacttt gttcattttt cagccaagga
     6901 tgtggttcgc catccagttg tcgctcagat tatccgagcc tatgaatatt ctactgaagt
     6961 tgcacacgac tgattttgag gaagttcgcc tgcaaaagaa tatacttttg agagaggaaa
     7021 atccagttgt ataggctaaa ggttttatcc aaaggtttga gacaacgatt aggcacgatg
     7081 gaaagaactt ttatgtggct gatgacgatc agtgcatctt cctgtgtcat aatcacaggg
     7141 cacaagaaag taggaatttg aaaagatgat tgaccaacta tctaagtatt acagttgtag
     7201 gatactaact gaaaaggata ttccaagtat tttatcttta tatgaaagta atcctctgta
     7261 ttttcagcat tgtccaccag agccaaattt tgcaactgta aaagaggaca tgctttgtct
     7321 acctgaaggt aaagctaagg ctgataagtt tttttgttgg attttggaat ggatctgacc
     7381 ttgtggctgt tatggatttt gtctatgcat atcctgatga ggagactgtt tttattggtt
     7441 tgtttatggt tgatccagcc tatcagagga aagggattgg tagtcatatt gtgacagaag
     7501 cactagctta ttttgctaag aactttcgaa aggcacgttt ggcttatgtt aagggaaatc
     7561 cgcaatctca gcatttttgg gaaaagcagg gctttaaatc aattggatgc gaggttaaga
     7621 aagaactcta tacggttgtt atcgttgaac agagcctaga agattagaaa tggcatcaag
     7681 taagaactat ttggaatttg ttttggaaca attatcagga ttagatgatg tgacttaccg
     7741 ttccatgatg ggggagtata ttctttactt ccgcggcaag attattggcg gcatttatga
     7801 cgatcgcttt tagttaaacc cgtgcaagca gtcttagata agattgacca atcttctttt
     7861 gagtttccat acaaaggtgc caaagaaatg atttgagtgg aagaacttga taataagatg
     7921 tttctataag acctgatttt agctatgtat aaccaactgc caacgcccaa acctaaaaag
     7981 aaaaagcaag ggtgaacgaa gtaaaaaaga agtctgctaa ggccctgtct ttgcacgggt
     8041 aaaattttat atataaaaag aagctgggac taaagagctc agcttccttt ggtttatata
     8101 attgtcatta caagacgaag tggttgggcg aaactctgtt gactttattc aatttagagt
     8161 ttcttatgca caattgagtc tggaacgaaa gtctccagtt gcaaagtata cagtacaata
     8221 aaccaacgat gtaatagctg atgacacaaa gcacagtggg taggacttgc gaagtcaccc
     8281 ttttcttttc aaaatttata ctaaatcatt gatatcagtg tagtcacgat taagtccttg
     8341 agcaactggt aggctagtca agtaaccttg ataagtggtc acaccttgac gcaagccttc
     8401 atcttcagag attgcttgtg cgaatccttt gccagccaaa gcttcgatat aaggaagagt
     8461 gacattggtt agggcgatgg ttgaagtgcg ggcaaccgca ccagggatat tggcaacggc
     8521 atagtggaga acaccgtgtt tttcatagac gggttcatcg tgcgttgtca cacggtcagc
     8581 tgtttcgata aggccacctt ggtcaacagc aatgtcaacg atacagagcc tggacgcatt
     8641 tgtttgacca tctcatctgt caccaattcc ggtgcttttg caccagggat gagaatggct
     8701 ccaatcacca catcagcatc tctcacactt gcttcaatgt tgaatgaatt agacataaga
     8761 gtttgaattt gacttccaaa gacttcttct agaactgaga gacgcttggc actaatatct
     8821 aaaatagtca cttgagcacc aagaccaagg gcgatgcggg cagcatgtgt accgacgaca
     8881 ccatcaccga tgatagttac ttttcctttt ggaacacctg gtacaccacc aagtagaaca
     8941 ccagagccac cagcttgctt agtaaggaag tgagctccga tttaaacagc catacgacct
     9001 gcaacctcac tcataggaac gaggagcggt agttgtcctt gattgtcacg aacagtttca
     9061 taggcaattc ctgttgtttt tgctgctaac atagcatctg ctaattctgg agcagcggcc
     9121 atgtgcaagt aggtgaagag aagaagatcg tcgcgcaagt aaccgtattc agaacttaaa
     9181 ggttctttta ctttcacaac caactctgct gcccaagctt caccagcagt agcgacaatc
     9241 tcagctcctt gcttttgata gtcagcatca gtaaagccag aaccgagacc agcatttgtt
     9301 tcgataagga cacgatgacc acgactaact aagctatgaa cacctgcagg tgtgagggcg
     9361 acacggtttt cgttattttt aatttctttt gggattccga ttaacattga gataacctac
     9421 ctttcaattg acggtcttgt tttggttgtc acattccagt tcataaatca aaaatgtgac
     9481 ggtttcattg tatatgaaac cgcttcaaaa atcaagaaaa acttgtcatc caaatttttt
     9541 atgctagact agtgaaaatc aagctttgat tggttggaaa agtatggaat caatttttgt
     9601 aaaacttgcc cagtatccgt ctatagaaac ggagcgttta ttgcttagac ctgtaacttt
     9661 ggatgatgcg gaagcaatgt ttgactatgc ctcggacaag ggtaatacac gttacacttt
     9721 tccaaccaat caaagcttgg aagaaaccaa gaataacatt gctcagttct atttggctaa
     9781 tcccttggga cgttggggaa tagaactaaa aagcaatggt cagtttattg gaaccattga
     9841 cttgcacaag attgattctg ttcttaagaa ggcagctatt ggctacatta tcaataaaaa
     9901 gtattggaat caaggattaa cgacagaagc caatcgtgct gtgattgagc tagcttttga
     9961 gaagataggg atgaataagt tgactgccct tcacgataag gacaatcctg cgtcaggaaa
    10021 ggtcatggag aaatcaggca tgcgtttttc ccatgcagaa ccatatgctt gtatggacca
    10081 gcatgaaaaa gatcgaatcg ttacaagagt tcattatgtc ttgaccaagg aagactattt
    10141 tgcaaataaa taagcagttg aaaagaaatt tttcgactgt tttttcttca tcttacgaat
    10201 aatctaagag aggagaaaat atggaagcaa ttatcgagaa aatcaaagag tataaaatca
    10261 tcgtcatctg tactggtctg ggcttgcttg taggcggatt tttcctgcta aagccagctc
    10321 cacaaacacc tgtcaaagaa acgaatttgc aggctgaagt tgcagctgtt tccaaggatt
    10381 tggtatccga aaaggaagtg aagaaggaag agaaggaaga accccttgaa caagatctaa
    10441 tcacagtaga tgtcaaaggt gctgtcaaat cgccagggat ttatgacttg cctgtaggta
    10501 gtcgagtcaa tgatgctgtt cagaaggctg gtggcttgac agagcaagca gacagcaagt
    10561 cgctcaatct agctcagaaa gttagtgatg aggctctggt ttacgttcct actaagggag
    10621 aagaagcagt tagccaacag actggtttgg ggacagcttc ttcaataagc aaggaaaaga
    10681 aggtcaatct caacaaggcc agtctggaag aactcaagca ggtcaaggga ctgggaggaa
    10741 aacgagctca ggacattatc gaccatcgtg aggcaaatgg caagttcaag tcagtagacg
    10801 aactcaagaa ggtctctggc attggtggca aaacaataga aaagcttaaa gactatgtta
    10861 cagtggatta agaatttctc tattccccta atttacctga gttttctatt actttggctt
    10921 tattacgcta ttttctcagc atcttatctt gctttgttgg gctttgtttt tctgctagtc
    10981 tgtctcttta tccaatttcc gtggaaatct gctggtaaag ttctagtgat ttgtggaatc
    11041 tttggatttt ggtttgtttt tcaaaattgg caacagagtc aagcgagtca aaatctggcg
    11101 gattctgttg aaggggtacg gattttgcct gatactatta aggttaatgg tgatagtcta
    11161 tcctttcgtg gcaagtctaa cggtcgtgct ttccaagtct attataaact ccagtccgag
    11221 gaggagaaag aagcctttca agctttaacc gacctgcatg agataggact agaagggaag
    11281 ctttcggagc cagaagggca gagaaatttt ggtggcttta attaccaagc ctatctgaag
    11341 actcagggaa tttaccagac tctcaatatc aaaacaatcc agtcacttca aaagattggc
    11401 agttgggata taggagaaaa cttgtccagt ttacgtcgaa aggctgtggt ttggattaag
    11461 acgcactttc cagaccctat gcgcaattac atgacaggac tcttgctggg acatctggac
    11521 accgactttg aggagatgaa tgagctttat tccagtctag gaattatcca cctctttgcc
    11581 ctatctggta tgcaggtagg ttttttcatg aatggattta agaaacttct cttgcgattg
    11641 ggcttgaccc aagaaaagtt gaaatggctg acttatccct tttcccttat ctatgcggga
    11701 ctaactggat tttcagcatc ggttattcgc agtctcttgc aaaagctact ggctcaacat
    11761 ggggttaagg gcttggataa ttttgccttg acggtgcttg tcctctttat tgtcatgcca
    11821 aactttttct tgacagcagg aggagtcttg tcctgcgctt atgcttttat cctgaccatg
    11881 accagcaaag aaggggaggg gctcaaggct gttactagtg aaagtctagt catctccttg
    11941 ggcatattgc ccattctatc cttctatttt gcggaatttc aaccttggtc tatccttttg
    12001 acctttgtct tttcctttct atttgacttg accttcttac cgctcttgtc tattttattt
    12061 gtcctttcct ttctctatcc agtcattcag ctgaacttta tttttgaatg gttggagggc
    12121 attattcgct tggtgtcaca ggtgacaagt agacctctgg tctttggaca acccaatgca
    12181 tggtttttaa tcctattgtt aatttccttg gctttggtct atgatttgag aaaaaacatt
    12241 aaaaagctaa cggtattgtg cttattgatt acagggctct ttctcctgac caagcatcca
    12301 ctggaaaatg aaatcaccat gctggatgtg gggcaaggag aaagtatttt cctacgggat
    12361 gtaactggga aaaccattct catagatgta ggtggtaagg cagaatctta taagaaaatc
    12421 gaaaaatggc aagaaaagat gacgaccagc aatgcccagc gaaccttgat tccctatctc
    12481 aaaagtcgag gagtagctaa gattgaccag ctaattttga ctaacacgga caaggagaat
    12541 gttggagatt tgtcagaggt gaccaaggct ttccatgtag gggagattct agtatcaaaa
    12601 gacagtctga aacagaagga atttgtggca gaactacagg cgactcaaac aaaggtgcgt
    12661 agtatgacag taggggagaa cttgcccatt tttggaagtc agttagaagt tctatctcca
    12721 aggaaaatgg gagatggagg acacgatgat accctagttc tgtatgggaa attcttggat
    12781 aagcaatttc tcttcacggg aaatttggag gagaaaggag agaaggactt gctgaagcac
    12841 tatccagact tgaaagtaaa tgttttgaaa gctagccaac atggcaataa aaaatcatca
    12901 agtccagcct ttctagaaaa actcaaacca gagcttactc ttatctcagt tggaaagagc
    12961 aatcgaatga aactccccca tcaggaaaca ttgacacgac tggaaggtat caatagcaaa
    13021 gtttatcgaa ctgaccagca aggagctata cgttttaagg ggttggatag ttggaaaatc
    13081 gaaagtgttc gataggaagg ataaatgttg tagattagtg aaataaacta aaaatttgtt
    13141 gcataataat gataaaaatg gtataatgaa aacgtattca atattgagga tataaaatca
    13201 ttaaaaatca gcaaaagttg ttttattagt tagtttataa tctattggtc ttcttcagtc
    13261 cagtgtatct gctgtgacag tcactaaaag ttacaagtat gattggaata cggtttggga
    13321 atatagtacc aactatcacg accatcagta tgcttggatt ccgtcatggt ctcgttatga
    13381 cagctattct gagtataaag ttggcggagg ctggaactac gctcgttatg aggtcataaa
    13441 ctattacagc ggaggctatt aattcttaaa gagtgagaaa aaggagggct agatatgttg
    13501 cagcttactc atgtgacctt aaaaacgcga caagtcatct tgcaagatgt ggatttcacc
    13561 tttaaaaagg gtagggttta tggtcttctt gctatcaatg gctctggaaa gacgaccctg
    13621 ttccgtgcca ttagcaattt aattcccata agtagtggaa atatcgcagc ccctccttct
    13681 ttattttatt atgagagtat tgaatggctg gatggaaact taagtgggat ggactacctt
    13741 cgtcttatca aaaacatctg gaagtcaggt ctgaacttga gggatgaaat cgcctattgg
    13801 gaaatgtctg actatatcag tcttcccatt cgcaagtatt ccttaggcat gaagcaacgc
    13861 ttggtgattg ccatgtattt cctcagtcag gccaaatgct ggctcatgga tgagattaca
    13921 aatggcttag atgagtatta tcgacagaag ttttttgata ggctagcaca aatcgataga
    13981 caagaacagc tggttctttt aagttcccac tataaggaag agttggttga tgtctgcgat
    14041 agagtagtaa ccattcatca ggggcagata gaagaggttt agtttatgaa agatgttagt
    14101 ctatttttat tgaaaaaagt tttcaaaagc cgcttaaact ggattgtctt agctttattt
    14161 gtatctgtac tcggtgttac cttttattta aatagtcaga ctgcaaactc acacagcttg
    14221 gagagcaggt tggaaagtcg cattgcagcc aacgagaggg ctatcaatga aaatgaagag
    14281 aaactctccc aaatgtctga taccagctcg gaggaatacc agtttgctaa aaataattta
    14341 gacgtgcaaa aaaatctttt gacgcgaaag acagaaattc taactttact aaaagaaggg
    14401 cgctggaaag aagcctacta tttgcagtgg caagatgaag agaagaatta tgaatttgta
    14461 tcaaatgacc cgactgctag ccctggctta aaaatggggg ttgaccgcga acggaagatt
    14521 taccaagccc tgtatccctt gaacataaaa gcacatactt tggagtttcc gacccacggg
    14581 attgatcaga ttgtctggat tttagaggtt atcatcccaa gtttgtttgt ggttgctatt
    14641 atttttatgc taacacaact atttgcagaa agatatcaaa atcatctgga cacagctcac
    14701 ttatatcctg tttcaaaagt gacatttgca atatcctctc ttggagttgg agtgggatat
    14761 gtaactgtgc tgtttatcgg aatctgtggc ttttcttttc tagtgggaag tctgataagt
    14821 ggttttggac agttagatta tccctaccca atttatagct tagtgaatca agaagtaact
    14881 attgggaaaa tacaagatgt attatttcct ggcttgctct tagctttctt agcctttatc
    14941 gtcattgtgg aagttgtgta cttgattgct tactttttca agcaaaaaat gcctgtcctc
    15001 tttctttcac tcattgggat tgttggctta ttgtttggta tccaaaccat tcagcctctt
    15061 caaaggattg cacatctgat tccctttact tacttgcgtt cagtggagat tttatctgga
    15121 agattaccta agcagattga taatgtcgat ctaaattgga gcatgggaat ggtcttactt
    15181 ccttgcctga ttatcttttt gctattggga attctattta ttgaaagatg gggaagttca
    15241 cagaaaaaag aattttttaa tagattctag ctttcctata ggtagggaaa ataagtaaaa
    15301 actaacatag agagggaatc aacttgattc tctctttttg attcgaaaac caaaccaaaa
    15361 tacaaacaca aacttttcaa aaaataactt tttatcttga caagagctag aaaacttggt
    15421 atcatataaa agttgagaaa agcagaagtg agagcttctc gccttgtgac attaagttgc
    15481 ctggccctac ggatgaaaag tttcgaagaa acgctatcat aacgtgcggg cttgtatatt
    15541 tacaagtccg ctattgtttt tctctaataa aacaaaagag gtgaaaacca tagcaaagca
    15601 agacttattc atcaatgatg agattcgtgt acgtgaagtt cgcttgattg gtcttgaagg
    15661 agaacagcta ggtatcaagc cactcagtga agcgcaagct ttggctgata acgctaatgt
    15721 tgacctagta ttgattcaac cccaagccaa accgcctgtt gcaaaaatta tggactacgg
    15781 taagttcaaa tttgagtacc agaagaagca aaaagaacaa cgtaaaaaac aaagcgttgt
    15841 tactgtgaaa gaagttcgtc taagtccaac tattgacaag ggtgactttg atacaaaact
    15901 tcgtaatgca cgtaagttcc ttgaaaaagg aaataaagtt aaggtatcta ttcgctttaa
    15961 gggtcgtatg attacccata aagagattgg tgcaaaagtt ttagccgagt ttgctgaagc
    16021 aactcaagat attgccatca tcgaacaacg tgctaaaatg gatggacgtc aaatgttcat
    16081 gcaattggcg ccagcgactg acaaaaaata attgtcagaa agttaaataa aggagaaaaa
    16141 atcatgccaa aacaaaaaac acaccgcgca tcagctaaac gtttcaaacg tacaggttct
    16201 ggtggactta aacgtttccg tgcttacact tctcaccgtt tccacggaaa aactaagaaa
    16261 caacgtcgtc atcttcgtaa agcatctatg gtgcattcag gagattacaa acgtatcaaa
    16321 gcaatgctta ctcgcttgaa ataatagctt gactgtaagt aaacaattct aggaaatatt
    16381 tggaggaaat aaaacatggc acgtgttaaa ggtggcgttg tatcacgcaa acgtcgtaaa
    16441 cgtattctta aattagcaaa aggttactat ggagctaaac acatcttgtt ccgtactgca
    16501 aaagaacaag taatgaactc ttactactat gcataccgtg accgtcgtca gaaaaaacgt
    16561 gacttccgca aattgtggat tactcgtatc aatgcggcag ctcgtatgaa cggactttca
    16621 tactcacaat tgatgcatgg tttgaaattg gctgagatcg aagttaaccg taaaatgctt
    16681 gctgacttgg ctgttaacga tgcagtagct ttcacagctc ttgcagatgc agctaaagca
    16741 aaacttggta aataacaact gatgagactg gaacaggatt gtccagtctt ttttaaaata
    16801 aaggagaaag atatggcttc aaaaatgcta cacacttgct tacgagtaga aaatcttgaa
    16861 aaatcaatcg cattttatca agatgctttt ggttttaaag aattgcgtcg cagagatttt
    16921 ccagaccatg ccttcacgat tgtctatcta ggtcttgagg gtgatgatta tgagttggag
    16981 ttgacttata actacgatca cggtccgtat gtggttggtg atgggtttgc ccatatcgcc
    17041 ctcagtacac ctgatcttga ggcacttcat caagaacaca gtgcaaaagg ctatgaagtg
    17101 actgagccaa atggtctacc aggaactaca ccaaactatt actttgttaa agaccctgat
    17161 ggatataagg tcgaagtcat tcgtgaaaaa taatttcgtg caagttaagt agaatattcg
    17221 ttttctactt gacttttttt agctgaaaga gtatactaat aaaaattcaa cctttaaggg
    17281 gagtccagag agactcacaa ggtgtcagat aaaagaatag tgcaattttc tagaggagac
    17341 cttttgagtg tgctctcttg tgttgtacga ttttaactga ggccttgcac tagcaaggtc
    17401 ttttctttat ctggtcccct taaaatttaa ggaggaaaag ttatgaatct cacatgtaag
    17461 aagcgtttgg gtgtcattcg gttggaaacc atgaaggtgg ttgcacaaga ggaaatcgcg
    17521 ccagcaatct ttgaattagt cctagaagga gaaatggttg aagccatgcg agcaggccaa
    17581 tttcttcatc tgcgtgtacc agacgatgcc catctcttac gtcgtcctat ttcaatttcg
    17641 tctattgaca aggcaaacaa gcagtgtcac ctcatttatc ggattgaggg agctgggact
    17701 gcaatttttt caaccttaag tcagggagac actcttgatg tgatgggtcc tcagggaaat
    17761 ggttttgact tgtctgacct tgatgagcag aatcaggttc tccttgttgg tggtgggatt
    17821 ggtgttccac ccttgcttga ggtggccaag gaattgcatg aacgtggagt gaaagtagtg
    17881 acagtcctcg gttttgctaa taaggatgct gttattttga aaacggaatt ggctcagtat
    17941 ggtcaggtct ttgtaacgac agatgatggt tcttatggca tcaagggaaa tgtttccgtt
    18001 gttatcaatg atttagatag tcagtttgac gctgtttact cgtgtggggc tccaggaatg
    18061 atgaagtata tcaatcaaac ctttgatgat cacccaagag cctatttatc tctggaatct
    18121 cgtatggctt gtgggatggg agcttgctat gcctgtgttc taaaagtacc agaaagcgag
    18181 acggtcagcc aacgcgtctg tgaagatggt cctgttttcc gcacaggaac agttgtatta
    18241 taaggagaaa attatgacta caaatcgatt acaagtgtct ctacctggtt tggatttgaa
    18301 aaatccgatt attccagcat caggctgttt tggctttgga caagagtatg ccaagtacta
    18361 tgatttaaac cttttaggtt ctattatgat caaggcgaca acccttgaac cacgttttgg
    18421 gaacccaact ccaagagtag cagagacgcc tgctggtatg ctcaatgcaa ttggcttgca
    18481 aaatcctggt ttagaggttg ttttggctga aaagttacct tggctggaaa gagaatatcc
    18541 aaatcttcct attattgcca atgtagctgg tttttcaaaa caagagtatg cagctgtttc
    18601 tcatgggatt tccaaggcaa ctaatgtaaa agctatcgag ctcaatattt cttgtcccaa
    18661 tgttgaccac tgtaatcatg gacttttgat tggtcaagat ccagatttgg cttatgatgt
    18721 ggtgaaagca gctgtggaag cctcagaagt gccagtttat gtcaaattaa ccccgagtgt
    18781 gaccgatatc gttactgtcg caaaagctgc agaagatgcg ggagcaagtg gcttgaccat
    18841 gatcaatact ctggttggaa tgcgctttga cctcaaaacc agaaaaccaa tcttggccaa
    18901 tggaacaggt ggaatgtcag gtccagcagt ctttccagta gccctcaaac tcatccgcca
    18961 agtagcccaa acaacagacc tgcctatcat tggaatgggg ggagtggatt cggctgaagc
    19021 tgccctagaa atgtatctgg ctggggcatc tgctatcgga gttggaacag ctaactttac
    19081 caatccttat gcctgccctg acatcatcga aaatttacca aaagtcatgg ataaatacgg
    19141 tattagcagt ctggaagaac tccgtcagga agtaaaagag tctctgaggt aaactgcaat
    19201 caatctgttc ttgatttttt attagtttgt aatatgaatt taggagaatt ttggtacaat
    19261 aaaataaata agaacagagg aagaaggtta atgaagaaag taagatttat ttttttagct
    19321 ctgctatttt tcttagctag tccagagggt gcaatgacta gtgatggtac ttggcaagga
    19381 aaacagtatc tgaaagaaga tggcagtcaa gcagcgaatg agtgggtttt tgatactcat
    19441 tatcaatctt ggttctatat aaaagcagat gctaactatg ctgaaaatga atggctaaag
    19501 caaggtgacg actattttta cctcaaatct ggtggctata tggccaaatc agaatgggta
    19561 gaagacaagg gagcctttta ttatcttgac caagatggaa agatgaaacg aaatgcttgg
    19621 gtaggaactt cctatgttgg tgcaacaggt gccaaagtaa tagaagactg ggtctatgat
    19681 tctcaatacg atgcttggtt ttatatcaaa gcagatggac agcacgcaga gaaagaatgg
    19741 ctccaaatta aagggaagga ctattatttc aaatccggtg gttatctact gacaagtcag
    19801 tggattaatc aagcttatgt gaatgctagt ggtgccaaag tacagcaagg ttggcttttt
    19861 gacaaacaat accaatcttg gttttacatc aaagaaaatg gaaactatgc tgataaagaa
    19921 tggattttcg agaatggtca ctattattat ctaaaatccg gtggctacat ggcagccaat
    19981 gaatggattt gggataagga atcttggttt tacctcaagt ttgatggcaa aatggctgaa
    20041 aaagaatggg tctacgattc tcatagtcaa gcctggtact acttcaaatc cggtggttac
    20101 atgacagcca atgaatggat ttgggataag gaatcttggt tttatctcaa atctgatggg
    20161 aaaatagctg aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa
    20221 tccggtggtt acatgacagc caatgaatgg atttgggata aggaatcttg gttttacctc
    20281 aagtctgatg gcaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg
    20341 tactacttca aatctggtgg ctacatggcg aaaaatgaga cagtagatgg ttatcagctt
    20401 ggaagcgatg gtaaatggct tggaggaaaa gctacaaata aaaatgctgc ttactatcaa
    20461 gtagtgcctg tcacagccaa tgtttatgat tcagatggtg aaaagctttc ctatatatcg
    20521 caaggtagtg tcgtatggct agataaggat agaaaaagtg atgacaagcg cttggctatt
    20581 actatttctg gtttgtcagg ctatatgaaa acagaagatt tacaagcgct agatgctagt
    20641 aaggacttta tcccttatta tgagagtgat ggccaccgtt tttatcacta tgtggctcag
    20701 aatgctagta tcccagtagc ttctcatctt tctgatatgg aagtaggcaa gaaatattat
    20761 tcggcagatg gcctgcattt tgatggtttt aagcttgaga atcccttcct tttcaaagat
    20821 ttaacagagg ctacaaacta cagtgctgaa gaattggata aggtatttag tttgctaaac
    20881 attaataata gccttttgga gaacaagggc gctactttta aggaagccga agaacattac
    20941 catatcaatg ccctttatct ccttgcccat agtgccctag aaagtaactg gggaagaagt
    21001 aaaattgcca aagataagaa taatttcttt ggcattacag cctatgatac gaccccttac
    21061 ctttctgcca agacatttga tgatgtggat aagggaattt taggtgcaac caagtggatt
    21121 aaggaaaatt atatcgatag gggaagaact ttccttggaa acaaggcttc tggtatgaat
    21181 gtggaatatg cttcagaccc ttattggggc gaaaaaattg ctagtgtgat gatgaaaatc
    21241 aatgagaagc taggtggcaa agattagtac tataagtgaa tatgatttga gtgaatagta
    21301 agttaaaaat cctgatttca agtaaaatca ggattttttc atggatgcaa tttttttgga
    21361 gtctggtgtg acgcggaggg tcttttgtcc tgtgtaagtg acaaagccgg gttttccacc
    21421 agttggttta ttgagttttt tgacttcaat catatctacc tgcaccagat tcgacaggcg
    21481 cccttgagag aagtaggcag ctaactctgc tgcgtctgtc ttgactgcat cagatgggtc
    21541 aagatttcct gagatgacaa catggcttcc aggaatgtcc ttagcatgga accaaagttc
    21601 ctccttgcgg gccattttaa aggtcaattc ctcattttga agattgtttc gtccgacata
    21661 gatgatggtt ttgccatcgc ttgctagata ttgttctagt tttttgcgtt tctggatttt
    21721 ctcccgttgt cttctgcgga taaaacctgt ttgaatcaat tcttcacgga tttcagcgat
    21781 ttcttccagt ccagcttggt tgaggacggt ttctacactt tccagataga gaatagtggc
    21841 tttggtttct tcaatcaaat cagtcaagta tttgacagct tctttgagtt tctgataccg
    21901 tttaaaatag cgttgggcat tctggttggg agtcagagcc ttatcaagcg caatcatgat
    21961 aggttggttg gtatagtagt tgtctaggat aacctggtct tggtcgttag gcacttggtg
    22021 gaggaaggtt gtcagcaatt ctcctttttg acgaaattct tcagcgttgt ctgtcgccag
    22081 taactctttt tcctgttttt tgagtttgtg tcggtttttc tgaagttcat tttcaacacg
    22141 acgaatcagt tcactggcct gctgtttgac gcggtcgcgc tcagccttat ccttatagta
    22201 ggtgtccaac aaatcagaaa gatttgcaaa aggctctccc acctgatttg caaaaggaac
    22261 tggactgaag gaagtctcag tcaagcatgg cttggtttcc tgattgaaaa aatttcggaa
    22321 agcggaaagt ttttcactaa ccagtatcct ttccaattca tttgccgtat cgcgtcccag
    22381 accttgaaag aggctttgaa gattttttgc tgttagttct tgggtttgca ggatttcaaa
    22441 gagcttttca tccttgatag taaaaggatt gagagattct gtacttggcg gagcgatata
    22501 ggtcgatcct ggaagtaagg tgcggtagct attttgtgaa aaaccgacgt gtttgataac
    22561 ttcgaggatt ttatgactgc ttttatcgac cagtagaata ttactgtgtt tccccataat
    22621 ttcgataatc aaggtagcct ggatatggtc tccaatctcg tttttattgg aaactgtcat
    22681 ttccacaata cggtcatttt ccacttgctc aatcgactca atcagggccc cctgcaaata
    22741 ctttctcaaa accatgataa aggtagaagg ttgggctgga ttttcaaaag tcgtttgggt
    22801 cagctgaatg cgtccaaaaa ctggatgggc agaaaggagc aggcgatggc tttggcgatt
    22861 gctgcggatt tgcaagacca actcttgttc aaaaggctga ttgattttct ggatgcgacc
    22921 attcactaat tcgcttcgca attcctcaac tatgtggtgt aaaaaaaatc cgtcaaatga
    22981 catcgttctc tccttgtgat tgtattccat agtattatat caaaaaggta gaataaaatc
    23041 atggaaatgt ggtataataa agccaagtaa agagaaacga gaagcacatg tatattgaaa
    23101 tggtagatga aactggtcaa gtttcaaaag aaatgttgca acaaacccaa gaaattttgg
    23161 aatttgcagc ccaaaaatta ggaaaagaag acaaggagat ggcagtcact tttgtgacca
    23221 atgagcgtag tcatgaactt aatctggagt accgtgacac cgaccgtccg acagatgtca
    23281 tcagccttga gtataaacca gaattggaaa ttgcctttga cgaagaggat ttgcttgaaa
    23341 atccagaatt ggcagagatg atgtctgagt ttgatgccta tattggggaa ttgttcatct
    23401 ctatcgataa ggctcatgag caggccgaag aatatggtca cagctttgag cgtgagatgg
    23461 gcttcttggc agtacacggc tttttacata ttaacggcta tgatcactac actccggaag
    23521 aagaagcgga gatgttcggt ttacaagaag aaattttgac agcctatgga ctcacaagac
    23581 aataaacgaa aatggaaaaa tcgtgacctg atatccagtt tagaatttgc catcacaggg
    23641 atttttactg ctatcaagga agaacgaaat atgcgaaaac atgcagtgac ggctctagtg
    23701 gttatccttg caggttttgt ttttcaggtg tcacgaatcg aatggctctt tctcctattg
    23761 agcattttct tggtagtagc ctttgagatt atcaactctg ctattgaaaa tatggtggat
    23821 ttggccagtc actatcactt ttccatgctg gctaaaaatg ccaaggatat ggcggctggc
    23881 gcggtattag tggtttctct tttcgcagcc ttaacaggtg cattgatttt tctcccacga
    23941 atctgggatt tattatttta aacagtaaga ggaaattatg acttttaaat caggctttgt
    24001 agccatttta ggacgtccca atgttgggaa gtcaaccttt ttaaatcacg ttatggggca
    24061 aaagattgcc atcatgagtg acaaggcgca gacaacgcgc aataaaatca tgggaattta
    24121 cacgactgat aaggagcaaa ttgtctttat cgacacacca gggattcaca aacctaaaac
    24181 agctctcgga gatttcatgg ttgagtctgc ctacagtacc cttcgcgaag tggacaccgt
    24241 tcttttcatg gtgcctgctg atgaagcgcg tggtaagggg gacgatatga ttatcgagcg
    24301 tctcaaggct gccaaggttc ctgtgatttt ggtggtgaat aaaatcgata aggtccatcc
    24361 agaccagctc ttgtctcaga ttgatgactt ccgtaatcaa atggacttta aggaaattgt
    24421 tccaatctca gcccttcagg gaaataacgt gtctcgtcta gtggatattt tgagtgaaaa
    24481 tctggatgaa ggtttccaat atttcccgtc tgatcaaatc acagaccatc cagaacgttt
    24541 cttggtttca gaaatggttc gcgagaaagt cttgcatcta actcgtgaag agattccgca
    24601 ttctgtagca gtagttgttg actctatgaa acgagacgaa gagacagaca aggttcacat
    24661 ccgtgcaacc atcatggttg agcgcgatag ccaaaaaggg attatcatcg gtaaaggtgg
    24721 cgctatgctt aagaaaatcg gtagcatggc ccgtcgtgat atcgaactca tgctaggaga
    24781 caaggtcttc ctagaaacct gggtcaaggt caagaaaaac tggcgcgata aaaagctaga
    24841 tttggctgac tttggctata atgaaagaga atactaagta gaggtaggct catgcctgct
    24901 tcttgttttt acagaaggag acttatgcct gaattacctg aggttgaaac cgtttgtcgt
    24961 ggcttagaaa aattgattat aggaaagaag atttcgagta tagaaattcg ctaccccaag
    25021 atgattaaga cggatttgga agagtttcaa agggaattgc ctagtcagat tatcgagtca
    25081 atgggacgtc gtggaaaata tttgcttttt tatctgacag acaaggtctt gatttcccat
    25141 ttgcggatgg agggcaagta tttttactat ccagaccaag gacctgaacg caagcatgcc
    25201 catgttttct ttcattttga agatggtggc acgcttgttt atgaggatgt tcgcaagttt
    25261 ggaaccatgg aactcttggt gcctgacctt ttagacgcct actttatttc taaaaaatta
    25321 ggtcctgaac caagcgaaca agattttgat ttacaggtct ttcaatctgc ccttgccaag
    25381 tccaaaaagc ctatcaaatc ccatctccta gaccagacct tggtagctgg acttggcaat
    25441 atctatgtgg atgaggttct ctggcgagct caggttcatc cagctagacc ttcccagact
    25501 ttgacagcag aagaagcgac tgccattcat gaccagacca ttgctgtttt gggccaggct
    25561 gttgaaaaag gtggctccac cattcggact tataccaatg cctttgggga agatggaagc
    25621 atgcaggact ttcatcaggt ctatgataag actggtcaag aatgtgtacg ctgtggtacc
    25681 atcattgaga aaattcaact aggcggacgt ggaacccact tttgtccaaa ctgtcaaagg
    25741 agggactgat gggaaaaatc atcggaatca ctgggggaat tgcctcaggt aagtcaactg
    25801 tgacaaattt tctaagacag caaggctttc aagcagtgga tgccgacgca gtcgttcacc
    25861 aactacagaa acctggtggt cgtctgtttg aggctatagt acagcacttt gggcaagaaa
    25921 tcattcttga aaacggagaa ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc
    25981 ctgaagagca aaaatggtct aatcaaattc aaggggagat tatccgtgag gaactggcta
    26041 ctttgagaga acaattggct cagacagaag agattttctt catggatatt cccctacttt
    26101 ttgagcagga ctacagcgat tggtttgctg agacttggtt ggtctatgtg gaccgagatg
    26161 cccaagtaga acgcttaatg aaaagggacc agttgtccaa agatgaagct gagtctcgtc
    26221 tggcagccca gtggccttta gaaaaaaaga aagatttggc cagccaggtt cttgataata
    26281 atggcaatca gaaccagctt cttaatcaag tgcatatcct tcttgaggga ggtaggcaag
    26341 atgacagaga ttaactggaa ggataatctg cgtattgcct ggtttggtaa ttttctgaca
    26401 ggagccagta tttctttggt tgtacctttt atgcccatct tcgtggaaaa tctaggtgta
    26461 gggagtcagc aagtcgcttt ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg
    26521 gcgctctttt ctcctatttg gggtattctt gctgacaaat acggccgaaa acccatgatg
    26581 attcgggcag gtcttgctat gactatcact atgggaggct tggcctttgt cccaaatatc
    26641 tattggttaa tctttcttcg tttactaaac ggtgtatttg caggttttgt tcctaatgca
    26701 acggcactga tagccagtca ggttccaaag gagaaatcag gctctgcctt aggtactttg
    26761 tctacaggcg tagttgcagg tactctaact ggtcccttta ttggtggctt tatcgcagaa
    26821 ttatttggca ttcgtacagt tttcttactg gttggtagtt ttctattttt agctgctatt
    26881 ttgactattt gctttatcaa ggaagatttt caaccagtag ccaaggaaaa ggctattcca
    26941 acaaaggaat tgtttacttc agttaaatat ccctatcttt tgctcaatct ctttttaacc
    27001 agttttgtca tccaattttc agctcaatcg atcggcccta ttttggctct ttatgtacgc
    27061 gacttagggc agacagagaa tcttcttttt gtctctggtt tgattgtgtc cagtatgggc
    27121 ttttccagca tgatgagtgc aggagtcatg ggcaagctag gtgacaaggt gggcaatcat
    27181 cgtctcttgg ttgtcgccca gttttattca gtcatcatct atctcctctg tgccaatgcc
    27241 tctagccccc ttcaactagg actctatcgt ttcctctttg gattgggaac cggtgccttg
    27301 attcccgggg ttaatgccct actcagcaaa atgactccca aagccggcat ttcgaggatc
    27361 tttgccttca atcaggtatt cttttatctg ggaggtgttg ttggtcccat ggcaggttct
    27421 gcagtagcag gtcaatttgg ctaccatgct gtcttttatg cgacaagcct ttgtgttgcc
    27481 tttagttgtc tctttaacct gattcaattt cgaacattat taaaagtaaa ggaaatctag
    27541 tgcgagtaaa aattaatctc aaatgctcct cttgtgacag tatcaattac ctaaccagta
    27601 aaaattcaaa aacccatcca gacaagattg aggttttaaa gtattgtccc aaggaaagaa
    27661 aagtaaccct acatcttgaa tctaagtaga ttttatggta aaataatagg gattttaagg
    27721 agtttgatat gtataaccta ttattaacca ttttattagt attatctgtt gtgattgtga
    27781 ttgcaatttt catgcaacca accaaaaacc aatccagcaa tgtatttgat gccagttcag
    27841 gtgatttgtt tgaacgcagt aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag
    27901 ggattttagt ctttttctgg ctagccattg ccttagcatt gacggtatta tcaagtagat
    27961 aagaaaataa tgggcaggac taggtctttg cctcttttta tttttaaagg atgtttgaga
    28021 aggttttaca gtaaaagaaa attaaaaaat ctagaaagaa aatatgaaag atagaataaa
    28081 agaatattta caagacaagg gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa
    28141 agacagttcc aaggattttc gtgagttgat taaaaccttg tccttaatgg aaagaaagca
    28201 ccagattcgc tttgaagaag atggcagtct gaccttggaa gccaagaaaa aacatgagat
    28261 taccctcaag gggatttttc atgcccataa aaatggtttt ggttttgtca gcctagaagg
    28321 ggaagaggac gacctttttg tagggaaaaa tgatgtcaac tatgctattg atggtgatac
    28381 cgtcgaggta gtgattaaga aagtcgctga ccgcaataag ggaacagcag cagaagccaa
    28441 aattattgat atcctagaac acagtttgac aacagttgtc gggcaaatcg ttctggatca
    28501 ggaaaagcct aagtatgctg gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat
    28561 ttatgttaag aaaccagccc taaagttaga aggaacagaa gttctcaagg tctttatcga
    28621 taaataccca agcaagaaac atgatttctt tgtcgcgagt gttctcgatg tagtgggaca
    28681 ctcaacggat gtcggaattg atgttcttga ggtcttggaa tcaatggaca ttgtatccga
    28741 gtttccagaa gctgttgtta aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga
    28801 tatggaaggt cgtctggatc taagagatga aattaccttt accattgacg gtgcggatgc
    28861 caaggacttg gacgatgcag tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg
    28921 ggttcacatc gcagatgttt cttattatgt gaccgagggg tctgcccttg acaaggaagc
    28981 ccttaaccgt gcgacttctg tttacgtgac agaccgagtg gtgccaatgc ttccagaacg
    29041 actatcaaat ggcatctgct ctctcaatcc ccaagttgac cgcctgaccc agtctgctat
    29101 tatggagatt gataaacatg gtcgtgtggt caactatacc attacacaaa cagttatcaa
    29161 gaccagtttt cgtatgacct atagcgatgt caatgatatc ctagctggcg atgaagaaaa
    29221 gagaaaagaa taccataaaa ttgtaccaag tatcgaactc atggccaagc ttcatgaaac
    29281 tttagaaaac atgcgtgtga aacgtggagc tctcaatttt gataccaatg aagcgaagat
    29341 tttagtggat aaacaaggta agcctgttga tatcgttctt cggcagcgtg gcattgccga
    29401 gcggatgatt gagtctttta tgttgatggc taatgaaaca gttgccgaac atttcagcaa
    29461 gttggatttg ccttttatct atcgaattca cgaggagcct aaggctgaaa aggttcagaa
    29521 gtttattgat tatgcttcga gttttggctt gcgcatttat gggactgcca gtgagattag
    29581 ccaggaggca cttcaagaca tcatgcgtgc tgttgaggga gaaccttatg cagatgtatt
    29641 gtccatgatg cttcttcgct ctatgcagca ggctcgttat tcggagcaca atcacggcca
    29701 ctatggacta gctgctgact attatactca ctttaccagt ccaattcgtc gttatccaga
    29761 ccttcttgtt caccgtatga ttcgggatta cggccgttct aaggaaatag cagagcattt
    29821 tgaacaagtg attccagaga ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga
    29881 agctgagcgt gaagtcgaag ccatgaaaaa ggctgagtat atggaagaat acgtgggtga
    29941 agagtatgat gcagttgtat caagtattgt caaattcggt ctctttgtcg aattgccaaa
    30001 cacagttgaa ggcttgattc acatcactaa tctacctgaa ttttatcatt tcaatgagcg
    30061 tgatttgact cttcgtggag aaaaatcagg tatcactttc cgagtgggtc agcagatccg
    30121 tatccgtgtt gaaagagcgg ataaaatgac tggagagatt gatttttcat tcgtacctag
    30181 tgagtttgat gtgattgaaa aaggcttgaa acagtctagt cgtagtggca gagggcgtgg
    30241 ttcaaatcgt cgttcggata agaaggaaga caagagaaaa tcaggacgct caaatgataa
    30301 gcgtaagcat tcacaaaaag acaagaagaa aaaaggaaag aaaccttttt acaaggaagt
    30361 agctaagaaa ggagccaagc atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa
    30421 aggcacgcca cgactataca atcgtagata cgctagaggc agggatggtc ctgactggaa
    30481 ctgaaatcaa gagtgtacga gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga
    30541 aaaatggaga agtttggctg agtaatgttc atatcgcgcc ttacgaagag ggcaatatct
    30601 ggaaccagga accagaacgt cgtcgtaaac tcctgctcca taaaaagcaa attcaaaaat
    30661 tggaacaaga gaccaaaggg acaggaatga ccttagttcc ccttaaggtc tatataaaag
    30721 atggctacgc taagcttctt ttaggacttg ccaaagggaa gcatgactat gacaaacggg
    30781 agtctatcaa acgtcgtgag caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc
    30841 agcgataaaa agaggaattg aaaatggaaa aattagttgc ctataaacgc atgcctttgt
    30901 ggaataaaca aacaatgcct gaagctgttc agcaaaagca caatacaaaa gttgggactt
    30961 gggggaaaat tactgtcttg aagggagctc tcaagtttat tgaattgaca gaagaagggg
    31021 aagttctagc tgaacacctc tttgaagcag gggcagacaa tccaatggcc caacctcaag
    31081 cctggcaccg agtggaagct gccacagatg atgtggaatg gtacttggaa ttttattgta
    31141 aacctgagga ttattttgct aaaaaataca ataccaatcc tgttcattca gaggtcctag
    31201 aggccatgca gacagtgaaa caagggaaag ctttggattt gggttgtggt caggggcgta
    31261 attctctttt tctagcccag caagattttg atgtgacggc tgtagatcaa aatggactag
    31321 ctcttgaaat cttgcaaagc attgtggagc aggaagattt ggacatgcct gttggccttt
    31381 acgatatcaa ttcagctagc attgaacaag aatatgattt tatcgtttca acagttgttc
    31441 tcatgtttct acaagcggac cgcattccag ctattattca aaatatgcag gagaaaacca
    31501 gtgttggtgg ttacaacctt atcgtttgtg ccatggacac ggaggattat ccttgctcgg
    31561 ttaacttccc attcaccttt aaagaaggag aactggcaga ctattacaag gattgggaat
    31621 tggttaagta caatgaaaat ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta
    31681 ttcaactacg ctttgcgacc ttactagcta agaaaatcaa gtaaacacac atgaagatta
    31741 ggaattttcc tgatcttttt tcttttttac gaatgatata gaaaaggagg gaattcatgt
    31801 ttgttgcgag agatgctagg ggagaattgg taaatgtgtt agaggataaa cttgagaagc
    31861 aagcatacac ctgcccagct tgtggaggcc agctccattt gcgtcaagga ccaagtgtac
    31921 ggacgcattt tgcccataaa tctttaaaag actgtgattt tttctttgaa aatgaaagtc
    31981 cagaacacct ggccaataag gaatccctct atcactggtt gaaaaaagag acaaaggttc
    32041 aattagagta cccgctttca gaacttaaac agattgcgga tgtatttgta aatggcaatc
    32101 tagctctaga agttcagtgt agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg
    32161 gctatcgtag tcagggttac caagtactgt ggttgctggg tcaaaaactg tggctcaagg
    32221 agcgtttgac tcgtctacag caaggttttc tttatttcag tcaaaacatg ggcttttatg
    32281 tttgggaatt agacaaggga aaacaagttt taagactcaa atacctgatt taccaggatc
    32341 tccgcggtaa actccattat caaatcaagg aattttccta tggccaaggt agtttattgg
    32401 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
    32461 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
    32521 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
    32581 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
    32641 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
    32701 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
    32761 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
    32821 cgatctaccc aactgaccag gcttgggaag aagccttaaa agatttaaca gaacaattgg
    32881 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
    32941 ctgaattttc tcttgaaatg gaacgccaga tagagaagct ttacgtttat gctcatatga
    33001 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacac
    33061 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
    33121 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
    33181 ttgacaagct cttgcaaggc aaggatcacg ttctttcaca acgtgaagaa gaattattgg
    33241 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
    33301 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
    33361 cttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
    33421 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
    33481 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
    33541 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
    33601 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
    33661 agatgtacga tgtctacaca ccgctttcat ctgttgaata caattttacc taccaagaag
    33721 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtca
    33781 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
    33841 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
    33901 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
    33961 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
    34021 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
    34081 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
    34141 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
    34201 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
    34261 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
    34321 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
    34381 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
    34441 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
    34501 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
    34561 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
    34621 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
    34681 ttgaaagaat tggaagactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
    34741 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
    34801 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
    34861 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
    34921 agtcgcaagc aaatcactct cctagaggga gatgcggttg atgtcttatc tacactgaca
    34981 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
    35041 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
    35101 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
    35161 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
    35221 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
    35281 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
    35341 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
    35401 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
    35461 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
    35521 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
    35581 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
    35641 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
    35701 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
    35761 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
    35821 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
    35881 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
    35941 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
    36001 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
    36061 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
    36121 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
    36181 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
    36241 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
    36301 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
    36361 aaaacgcata gtacaaggtt tgtactgccc ccaaaagtta gacaattaat ttatctgaag
    36421 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tc
//
LOCUS       DAVLTG010000017        35646 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLTG010000017 DAVLTG010000000
VERSION     DAVLTG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.017"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(179..1813)
                     /locus_tag="VYN12_000892"
     CDS             complement(179..1813)
                     /locus_tag="VYN12_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415304.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLVNLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSTFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1794..2543)
                     /locus_tag="VYN12_000893"
     CDS             complement(1794..2543)
                     /locus_tag="VYN12_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415305.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPAQSLESIYLSLAGRKEEVADASQGH"
     gene            2722..4176
                     /locus_tag="VYN12_000894"
     CDS             2722..4176
                     /locus_tag="VYN12_000894"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1415306.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4266..6884)
                     /gene="alaS"
                     /locus_tag="VYN12_000895"
     CDS             complement(4266..6884)
                     /gene="alaS"
                     /locus_tag="VYN12_000895"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1415307.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6906..7391)
                     /locus_tag="VYN12_000896"
     CDS             complement(6906..7391)
                     /locus_tag="VYN12_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1415308.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSNFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7666..7905)
                     /locus_tag="VYN12_000897"
     CDS             complement(7666..7905)
                     /locus_tag="VYN12_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415309.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8158..9228)
                     /locus_tag="VYN12_000898"
     CDS             complement(8158..9228)
                     /locus_tag="VYN12_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1415310.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9225..9998)
                     /locus_tag="VYN12_000899"
     CDS             complement(9225..9998)
                     /locus_tag="VYN12_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415311.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILTQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9995..10801)
                     /locus_tag="VYN12_000900"
     CDS             complement(9995..10801)
                     /locus_tag="VYN12_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415312.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVALLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10782..11939)
                     /locus_tag="VYN12_000901"
     CDS             complement(10782..11939)
                     /locus_tag="VYN12_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415313.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(11998..12948)
                     /gene="murB"
                     /locus_tag="VYN12_000902"
     CDS             complement(11998..12948)
                     /gene="murB"
                     /locus_tag="VYN12_000902"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1415314.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(13060..13819)
                     /locus_tag="VYN12_000903"
                     /pseudo
     CDS             complement(13060..13819)
                     /locus_tag="VYN12_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13829..14560)
                     /gene="budA"
                     /locus_tag="VYN12_000904"
     CDS             complement(13829..14560)
                     /gene="budA"
                     /locus_tag="VYN12_000904"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1415315.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14702..15973
                     /locus_tag="VYN12_000905"
     CDS             14702..15973
                     /locus_tag="VYN12_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1415316.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15993..16808)
                     /locus_tag="VYN12_000906"
     CDS             complement(15993..16808)
                     /locus_tag="VYN12_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1415317.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(16965..17618)
                     /gene="phoU"
                     /locus_tag="VYN12_000907"
     CDS             complement(16965..17618)
                     /gene="phoU"
                     /locus_tag="VYN12_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1415318.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17630..18388)
                     /gene="pstB"
                     /locus_tag="VYN12_000908"
     CDS             complement(17630..18388)
                     /gene="pstB"
                     /locus_tag="VYN12_000908"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1415319.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18401..19204)
                     /gene="pstB"
                     /locus_tag="VYN12_000909"
     CDS             complement(18401..19204)
                     /gene="pstB"
                     /locus_tag="VYN12_000909"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1415320.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19215..20099)
                     /gene="pstA"
                     /locus_tag="VYN12_000910"
     CDS             complement(19215..20099)
                     /gene="pstA"
                     /locus_tag="VYN12_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1415321.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20089..21006)
                     /gene="pstC"
                     /locus_tag="VYN12_000911"
     CDS             complement(20089..21006)
                     /gene="pstC"
                     /locus_tag="VYN12_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1415322.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21006..21884)
                     /gene="pstS"
                     /locus_tag="VYN12_000912"
     CDS             complement(21006..21884)
                     /gene="pstS"
                     /locus_tag="VYN12_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1415323.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22458..23762)
                     /locus_tag="VYN12_000913"
     CDS             complement(22458..23762)
                     /locus_tag="VYN12_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1415324.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23763..24536)
                     /locus_tag="VYN12_000914"
     CDS             complement(23763..24536)
                     /locus_tag="VYN12_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1415325.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24526..24804)
                     /locus_tag="VYN12_000915"
     CDS             complement(24526..24804)
                     /locus_tag="VYN12_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1415326.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24804..25205)
                     /locus_tag="VYN12_000916"
     CDS             complement(24804..25205)
                     /locus_tag="VYN12_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1415327.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25415..26032)
                     /locus_tag="VYN12_000917"
     CDS             complement(25415..26032)
                     /locus_tag="VYN12_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1415328.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(26022..26795)
                     /locus_tag="VYN12_000918"
     CDS             complement(26022..26795)
                     /locus_tag="VYN12_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1415329.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26806..27543)
                     /locus_tag="VYN12_000919"
     CDS             complement(26806..27543)
                     /locus_tag="VYN12_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1415330.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27548..28678)
                     /locus_tag="VYN12_000920"
     CDS             complement(27548..28678)
                     /locus_tag="VYN12_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1415331.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28762..29151)
                     /locus_tag="VYN12_000921"
     CDS             complement(28762..29151)
                     /locus_tag="VYN12_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1415332.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29167..29550)
                     /locus_tag="VYN12_000922"
     CDS             complement(29167..29550)
                     /locus_tag="VYN12_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1415333.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29551..30339)
                     /locus_tag="VYN12_000923"
     CDS             complement(29551..30339)
                     /locus_tag="VYN12_000923"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1415334.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(30332..31267)
                     /locus_tag="VYN12_000924"
     CDS             complement(30332..31267)
                     /locus_tag="VYN12_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1415335.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31397..31573)
                     /locus_tag="VYN12_000925"
     CDS             complement(31397..31573)
                     /locus_tag="VYN12_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1415336.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31713..32420)
                     /locus_tag="VYN12_000926"
     CDS             complement(31713..32420)
                     /locus_tag="VYN12_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1415337.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32571..33599
                     /gene="queA"
                     /locus_tag="VYN12_000927"
     CDS             32571..33599
                     /gene="queA"
                     /locus_tag="VYN12_000927"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1415338.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34260..34649)
                     /locus_tag="VYN12_000928"
     CDS             complement(34260..34649)
                     /locus_tag="VYN12_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1415339.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(34703..35394)
                     /locus_tag="VYN12_000929"
                     /pseudo
     CDS             complement(34703..35394)
                     /locus_tag="VYN12_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
BASE COUNT        10650 a         8124 c         6739 g        10133 t
ORIGIN      
        1 gaaaaatatc caaataaata aactataaac aacaaaaata gaactatgtt atatttctta
       61 ttcaaaacat tcctccctat atatttttga ttaccaatct taatcattta caactacatt
      121 ctaacaaact ataaaagcgt ttgtcgaatt gaatttatca agcaagcgac caaccagctc
      181 atcttttttc tatttctgcc aatatgcgtg acaggtaata atgatagcca aaaatagcaa
      241 gagcaagcag gaggataaga gctcctactc ccaagttgat ggcaaggata ggggagagag
      301 actgaaccaa gaatatgctc ccaattacaa gggccatcag gattgcacta taaataaaca
      361 ataaaactat ggcgactatg ccatttgaac gattcaccag gtccgtaatg ctactccaat
      421 tggttgacag atttttaacg tccttaaagt aatggtggca agaaaggatg acactggcaa
      481 tgatccagac tacaagaagg taaatcatcg aaaggatgga caagcctaga tatagagaaa
      541 gaccgagcaa agtcagaact ggtaaaaagg actgaacagc aaagataatc caaaatttca
      601 ctttcacata acgagcaaag tcaaagggta aactcttcag aaaatcaaca ttttccctct
      661 ccaaggacaa ggcaattgaa tgcaggctgg tgatattgtt attgacaact gctataaaca
      721 ctcctacaaa aaacaagggt aaccagtatg gaggatgaat gtctggaact atctgagaat
      781 ctcggatttt ggaaatcaga ctgatcatca tgagataagg aaggaaagta cttgtaaaaa
      841 gcactgtaat cacgccagtc ccctgtccca agagggtgag gtggtagcgt aaaaccatgc
      901 ggaaaaatcc ctttttagta gttgaaatcc tctccttgct gcgacgttct tttttgacct
      961 tctcctcact gttaagcagg atcacgtcat aaaaacgagg aaggaccttc tttttggtca
     1021 ggtaaagcaa gaaaacagtt aaagctatcc aagcgagcag acccactaag gcttctgtcg
     1081 aaaaaggctc cactgctatt ttgtaaaaga tatgaagagg ataaaggaga aatggaatgt
     1141 ctctaacttt gtcaacaata cttccaaaag tcgactgtag aaagaagaca aatattaaag
     1201 gtatgagaac tcctatccca atcatcacat tcgaaaaaat agactgatac tttctgaaga
     1261 ccctagtctg agccaagaaa tgtactgcca ctaccgtcac taaagtaaca gagacaaata
     1321 ataaggtcaa ggacagtagc atcaaaggca aacccagcca aagagaagga gctagactaa
     1381 tatagagggc tagaaaataa gctaggattg gtacaattcc agttagagct ggcaaaagga
     1441 cagacagtcc tttagcaatt ataatctctg attctttaaa ggcatagggc ctatacgata
     1501 ccaaatcctt actctcataa aagacattgt aaaaggccgt taaagaagtt gaaaaggcaa
     1561 tcactagtaa aatagcaacc atcgagctaa aataaatagg tatttcctca aaaggaaaat
     1621 gaatggctat attactaaaa cagatgagca tcaagagact ggaaaaaatg taagaactta
     1681 ggactctagc ggaaacattt acttttttcc caggattctt agcctgcttc tttcgtagat
     1741 taaccagatt agcttcttga gatgaataaa ggatattgat atcaactaat tttttaatga
     1801 ccttgagacg catccgcaac ctcctctttt ctaccagcaa gactaaggta gatactttcc
     1861 aaagactggg ctgggtaatc ttttctcaag tcctctacac taccacaata aatcaaatgc
     1921 ccctttttca aaatggcaat ccgatcacag acttgctctg ccacctctag gacatgagtt
     1981 gaaaacaaga ctgtcttccc tttttgtgca tgttccttca tcatctgttt caaatcaaag
     2041 gcagcctggg gatccaaacc agtcaagggt tcatccaaga cccaaatatc gggatcagac
     2101 aagagtgctc cgatgacaaa gactttctga cgcattccgt gagaaagagt ttcaataacc
     2161 tgatagcgat tttcagcaaa atcaaaaacg ttcaatagcc tagctagact agtctccaag
     2221 tcagagctag tcagatcata ggatgaggcg atcaattccc aaaattcatt ggccgttaaa
     2281 cgtaaaaata agtcaggcga gtctgctacg tagccaatct ttcgtttgat cgccaagcga
     2341 ttttccgata actcctgacc atctaccaaa atacgaccac tgctgggtga aatgatactg
     2401 actagggatt ttatggtggt cgattttcca gccccattat gaccaatcaa gcccataatc
     2461 tctccatttt caatctgcaa attgagatta ctcaaggcct ctttatcacc atacaactta
     2521 ctaacatttt gaaattcaat catgggatga ctcctatctt tatctgtatt atacatcgct
     2581 atactagcac tttgatacaa aaaaatcaat actttatttt aagtagttaa aatagtttcc
     2641 ttctatctta cgcaaacgtt tgctccgaga gatactttat gatagaataa agaacaagat
     2701 tgacaagtaa gaggaaacat catgcaaaat caaacactca tgcaatactt tgaatggtat
     2761 ctgccccacg acggtcaaca ctggacgcgt ctggctgaaa atgctccaca cctagctcat
     2821 ctggggatca gtcacgtctg gatgccacca gccttcaagg caaccaacga aaaagatgtc
     2881 ggctatgggg tctatgactt atttgactta ggagagttca accaaaaagg gactgtccgc
     2941 accaagtatg gtttcaaaga agactatctt caagccattc aagcccttaa agcgcaggga
     3001 attcaaccta tggccgatgt agttctcaac cacaaggctg ctgctgatca cagggaagcc
     3061 tttcaggtta ttgaagtgga tcctgtagac cgtacagttg aacttggaga acccttcacc
     3121 atcaatggct ggactagttt taccttcgat ggtcgccaag atacctacaa tgacttccac
     3181 tggcactggt accacttcac aggtacagac tatgatgcca aacgccgtaa atccgggatt
     3241 tacctaatcc aaggagacaa caagggctgg gctaacgagg aattggtcga taacgaaaac
     3301 ggaaactacg actacctcat gtatgccgac ctagacttta aacatcctga agtcatccaa
     3361 aacatctatg actgggctga ttggttcatg gaaacgactg gtgtagctgg tttccgtttg
     3421 gatgccgtta agcatattga ctctttcttt atgcgcaatt tcatccgcga tatgaaggaa
     3481 aaatacggtg acgatttcta tgtttttggt gaattttgga acccagacaa ggaagccaat
     3541 ctggactatc tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg tctccaccag
     3601 aatctctttg aagccagtca agctggcgca aactatgacc ttcgtggcat tttcacagat
     3661 agcctggttg aactcaagcc tgacaaggct gtgacttttg tcgacaacca cgatacccaa
     3721 cgaggacaag cccttgagtc taccgttgaa gaatggttca agccagcagc ctatgccctc
     3781 attttgttac gccaagacgg ccttccatgt gtcttttacg gagactacta tgggatttca
     3841 ggccagtatg ctcaagaaga tttcaaagaa atccttgacc gcctcctagc catccgaaaa
     3901 gacttggcct atggagaaca aaatgactac tttgaccatg ctaactgtat cggttgggta
     3961 cgttcaggtg ctgaaaatca atccccaatc gcagtcctta tctcaaatga ccaagaaaac
     4021 agcaagtcaa tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga tttacttggt
     4081 aaccaccaag gtcaagttac aattgatgag gaaggttatg gacaattccc tgtctcagct
     4141 agatccgtaa gtgtctgggc agtcaatacc atctaatagc tcataataac caagctaggt
     4201 ccaagcggat ttggcttttt tgtattcaca aaaagaccta cccaaatgga tagatcttta
     4261 cttgattaca atttacctgc tactgcatcc aacaattctt ggatcttagc ttggttgctt
     4321 cctcctgcca tggccatgtc tggtttacca ccaccacgtc catcgatgat tggtgctaat
     4381 tctttgacaa ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag gacattgact
     4441 ttgtcaccga tagcggcaac taggacaaga agatcagagt agtctttttg tttccagtta
     4501 tctgcaaaag tacgaagggc accggcatcg gatacagaca cttgactagc aatgtaacga
     4561 tgaccgttga cttccttaac atctttgaag atatcgcctg cggctgcagc tgcggctttt
     4621 tctttcaact cagcattttc tttttgaagt tgacgaagtt gttcttgaag tccttctacc
     4681 ttgtgaggta cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc tttaagagca
     4741 tcctcttgtt cacgataggc ttcaaaggct tccttaccag tcactgccaa gatacggcga
     4801 gttcctgaac cgattccttc ttctttgaca attttgaaga gaccaatctc agaagtgttg
     4861 ccaacatgag taccaccaca aagttcaata gagtagtcac cgatagtcac gacacgaact
     4921 tccttgccgt atttctcacc aaagagggcc atagctccca tttctttagc agtgtcaata
     4981 tccgtttcaa ctgtcttcac ttcaagtgct tcccaaattt tctcgttaac ttgctgttca
     5041 atcgcacgaa gttcctcagc agttactgct tggaagtggg taaagtcaaa gcgaaggaat
     5101 tcaacttcgt taagagatcc tgcctgtgtt gcgtggtttc caaggatatt gtgaagggca
     5161 gcgtgaagca aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg attgctatca
     5221 attgccaagg tatattcttg gttcaaggca agcggtgcaa ggacttcaac tgtatgaagg
     5281 gcttgaccat ttggggcttt ctgaacattg gtcacagtag ccacaacctt acctgactca
     5341 tccaagattt gtccgtagtc agctacctgt ccacccattt cagcataaaa tgacgtttcc
     5401 gcaaagataa gagaggcagt tccttctgaa acagctccta cttctgcatt gtcagcaacg
     5461 atagctacca atttagaaga caattggcta gcattgtagt tgaagacact ttctacagtg
     5521 atgttttgaa gagtttcatt ttgcataccc attgagccac ccttgacagc tgacgcacgc
     5581 gcgcgttctt gctgttcttt catggctgct tcaaaacctt cacggtctac agtcatacca
     5641 gcttcttcag caatttcttc agtcaattca actgggaatc cgtatgtatc atagagttta
     5701 aagacatctt gaccagcaat gacagattga cctttttctt tcaagtctgc cacaatgcct
     5761 tgggcaaagt gttgacctga gtgaagggta cgggcaaatg attcttcttc gctcttaacg
     5821 attttctcaa taaagtcacg tttctcaagc acttctgggt agtagctttc catgattttt
     5881 ccaacagttg gaacaagttt gtaaaggaaa ggctcgttga tacccaattt ttgaccatgc
     5941 atagaagcac gacggagaag acgacgaaga acataaccac gaccttcatt tcctggaagg
     6001 gcaccatcac cgatagcaaa tgaaagagaa cgaatgtggt ctgcgataac cttgaagctc
     6061 atgttgtcgc catcttggtc ataaacctta ccagacaatt tctcgacttc acggataatc
     6121 ggcataaaga ggtccgtttc aaagttggtc ttagcccctt ggataacagc caccaaacgc
     6181 tccaaaccag cgcccgtatc aatgttctta tgtggcaatt ccttgtattc gctacgagga
     6241 acagcagggt ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat ataacggtcg
     6301 ttttcaatat cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa ggcttcccca
     6361 cggtcaaaga agatttctgt atctggtcca gaaggtcccg caccgatttc ccagaagttg
     6421 tcctcaattg gaatcaagtg acttggatcc actcccactt caatccagcg gttgtaagaa
     6481 tctttatcgt ctggatagta ggtcatgtaa agtttttcag cagggaaatc aaaccattca
     6541 gggcttgtca aaagctcata agcccaagtg atagcttcgt cacggaagta atccccgata
     6601 gagaagttcc ccaacatttc aaacatggta tggtgacgcg cagtcttccc tacgttttcg
     6661 atgtcgttgg tacggatagc cttttgggca ttggtaatac gtggattttc agggataatg
     6721 gtcccgtcaa agtatttctt aagggttgct accccagagt tgatccacaa aagagttggg
     6781 tcatttacag gaaccaaact tactgatggt tctactgagt gacctttggt cgcccagaaa
     6841 tcaagccaca tttggcgtac ttgtgcacta gatagttgtt tcatattgtc tccttattca
     6901 cttgtttaat gtgattggct ttccagcatt tccacatagt caatcgcgac acagagggaa
     6961 atgactaggt ctgcataagc gtcttcaaga accgttacgg tataggtaga ggtcagatgg
     7021 aagagttcct tcttaatttc cgcaatcaac tgatcgcgat catccagcaa tttgaaattc
     7081 aaatcccaga tattgccctc gatacgaaga cctagattat caaactcata cttatctcgc
     7141 cagaaggtca acttcttacg aatgacaaaa ttcgagccat cccgaagctg aatctcaaaa
     7201 cgaggaagca aggtcaagat ttctttactg atctgactga cttgttcacc agccgcatca
     7261 tagatggtaa aagttttggg aatcttaaaa aatgatccct ccacctgata ggcaatttct
     7321 cccctgtcat ccttgatagc gaagcgttcg cctccaagac gaaacttttg tttgacaaga
     7381 aatgttttca tcaacacctc caaaaatcaa aagacaagct catatcacga agggcgaaaa
     7441 accgcggtac caccttcatt caatgaactt gtcattctct tgttcttatg caattgtatg
     7501 attgagtagc atgacttcct agcttagatg gctcgcagca ccgccatttc tctggactaa
     7561 gacaagtgaa aatcaattct caactttctt attataacgt ttttttaagc ttgcgtcaac
     7621 tggaaatgat ctccgttgaa ttagaccaat tccctacatc tctgattact ttttcaggat
     7681 atattttttc ttactgccat ttttcttttt atcccaaatt ttcatattac taaacacagc
     7741 tactagaata tttccaaata taaaggtgcc tatcacccaa tatatggact cagttgttag
     7801 gtattgtcga tccaagccat cctttaaatg gaatagtata gcagtttggt taacaatcat
     7861 aaaggttggc cagaaacttt ttttgaaaaa agtagacatt ttcattattt gttgccgctt
     7921 tctgtaaggt taatactcaa taaaaatcaa aaagcaaact aggaagctag cctcaagctg
     7981 tacttgagta cggcaaggca acgctgacgt ggtttgaaga gtataggctt agtatactac
     8041 taggcaagca aataaacaaa taaacaacta gaatagaaaa agatagggct ctaaaaactg
     8101 acttctattc cttaaaaacg aaccagcttg actgattcgt cttcttacgt ttatctccta
     8161 cttccgatac attttaaact gtaggaagag gtcgctatat ttccctgtcc atttatggtc
     8221 aaatttctca taaacttcta ggtgtttcat ggtttcaaca tcgggataga aggccttatc
     8281 ttcctttgtt tcctctggga gcaattcctt cgctggtagg tttggtgttg aatagccgac
     8341 atactccgca ttttggagag cattttcagg tttcaacata aagttgataa aggcataggc
     8401 tgagttttgg tttttaactg ttttgggaat gaccatattg tcaaaccaaa gattgctggc
     8461 ctctgtcggt accacataac gtagattttc atttttttct aacatttggc tggcttcacc
     8521 agagaaggtc acgccgattg caacattatt ctgaatcata tagcccttca tctcgtccgc
     8581 aacgatagcc ttgatatttg gagtcagttt gtagagctta tccactgtct cttccaactg
     8641 ctgcagatcc ttggagttga ggctgtagcc gagggaattg agtcctagtc ccagcacctc
     8701 acgcgcccca tcaaagagca tgatagaatt cttatactcc ggcttccaaa ggtcatccca
     8761 atgctcaggc gcttcatcta ccatggtttc gttgtagaca attcctaagg ttccccagaa
     8821 gtaagggatg gagaatttat tacctgggtc aaaggactgg ttgagaaact ctggtccgat
     8881 attttcgatt ccttcaattt ttgaataatc aagcggaacc aagaggtctt cgtccttcat
     8941 cttgttaatc atgtattcac ttggaatggc aatatcgtag gtcgttccac cctgctttat
     9001 cttagtgtac atggcttcgt tggagtcaaa agtctcgtac tgaacttgaa ttcctgtttc
     9061 ttctgtaaac tgagtcaaga gttcaggatc gatatagtct ccccagttat agataaccaa
     9121 tttttgacta tctcgactat tgattttact atctaaatga gtcgcaattc cccacaagac
     9181 aaggataatc gctgcaattc ctgctaaaaa tgaatagatt tttttcatgc ttgctcctcc
     9241 ttctcacgag agataaagta ataacctaca actaggataa tactaaagag aaagactaga
     9301 gcagacaggg cattgatttc taaggaaatc cccttgcgag cacgagagta aatctcgact
     9361 gatagggttg aaaagccatt tcctgttaca aagaaggtca cggcaaagtc atctaacgaa
     9421 taggtgaagg ccatgaaata accagtaatg atagacggag tcaggtaagg aagcatgatt
     9481 tccttgaaca tctgaaattg actagctccc aagtcatagg ccgcatgaat catgtcgcca
     9541 ttcatttcct tgagtcgagg caagaccatc aagaccacga taggaatgga gaaggccacg
     9601 tgactagata gaacggtcaa aaagccaagt gaaaacttga gttgggtaaa gagaatcaag
     9661 aagctagcac caatcataac gtcaggcgca accatgagga tattattgag tgatagaaag
     9721 gcttcttggt atttcttacg agactggtag atgtaaatgg caccaaaagt cccgataatg
     9781 gtcgctatca aggctgatag gaaggccaag aaaaaggtct gagtcaaaat cagcatgagt
     9841 ctcccatctc caaacatggt ttcaaagtga gtccagctaa aacctgtaaa gctattcata
     9901 tcatcaccag cattaaaggc atagccaatc aagtaaaaga taggcaggta gaggaccaga
     9961 aagaccagtc ccagataaag gttggcaaat tttttcatcg ttctctcctt tccttagtca
    10021 cccacatggt gatgaacatg gtcaggatga gaatcacacc gatggttgaa cccataccat
    10081 agttgtcatt ggttagaaaa ttctgctcaa tagccgtccc caaggtgata acgcggttcc
    10141 caccaatcaa acgggtcagc atgaagagac tcaaacttgg gataaagacc gactgaaccc
    10201 cacttcgcac accgttcata gatagaggga agatgacatg acggaaggtc tcccacttag
    10261 ttgcaccaag gtcataacta gcattgatga gattattatc catatcgtct aagacattga
    10321 aaatcggcaa aatcataaag gggagctcga tgtagcttgc gacaaagata aaggaaaaat
    10381 cggtaaaaag caactgttgt gaaccaattc cgataaattc caagaattgg ttaatagagc
    10441 cattttgacc aaaaatcccg ataaaagcat aggctttaag gagcaaattg atccaggtag
    10501 gaaggataat cagcatgagc cagagttgac ggtgtttgag acgggtcaaa aagagggccg
    10561 tcggataact gataagcagt gccacaaagg tcacaatgcc tgcataaagc actgagttga
    10621 aactcatttt aagataggtc aagttttgtg acgcaaagta agatttgtaa ttttctaaac
    10681 tgaactggcc ttcgatgttg aaaaaggatt gaccgaaaat caagaccaag ggtgccaata
    10741 caaagagcgc aatccaaagc atgtagggta ctacaaagag tttagagctt gttttcttca
    10801 tctctttcct cctcgattgc attgatcaaa cctgcttctt gctcttcgat ttctacgtac
    10861 tcctcaatac gagcatcgaa ctcttcttcg gtttcattga gacgcatgat gtggatgtct
    10921 tctggttcaa agtccagacc gatttcctca cccacgatag ccttacgggt tgagtggatc
    10981 atccattcat ttccaagttc gtcataggcg ataatttcat aatgaactcc acggaaaagc
    11041 tgggtatcga ccttaacttg gagcttgcct tcttcaggaa gggtaatgcg caagtcctct
    11101 ggacgaataa cgacctcaac aggttcattt ggcttcatcc caccatcaac cgcttcaaag
    11161 cgtttgccgt taaattcgac caagtagtcc tcaatcatgg tacctggcaa gatgtttgac
    11221 tccccgataa aggtggcaac aaagtggttg attggctcat cgtagatgtc cacaggggtt
    11281 ccagactgga caatctcgcc atcattcata acgaaaatcc agtcactcat ggcaagagct
    11341 tcttcctgat cgtgagtgac aaagacaaag gtaatgccca atcgttgttg taattcacgc
    11401 aattcgtact gcatgtctgt tctcaatttc aagtccagcg ctgataaagg ctcgtccaac
    11461 aagaccacac ggggttggtt gatgatagca cgggcgatgg ccacacgctg acgttgtcct
    11521 ccagaaagtt tgcggatgga acgtttttca taaccttcca actgaaccat cttgagaact
    11581 tccgctacac gctgctcgat ttctttctta tcaattttac gcaagcgaag tggaaaggca
    11641 acattttcaa acacattcat atgtgggaac aaggcatagg attggaagac ggtatgtacg
    11701 tcgcgcttgt tggttggaat atcattgata cgaacaccgt ctagcatgat atctcctgtc
    11761 gtcgcatcca gtaaacctgc aataatgttt aggatagttg atttccccga accagatgca
    11821 cctagaaggg tgtagaattt cccttcttcc aactcaaagt tgatgtcttt gagaaccttg
    11881 gtgttgctgt cttcaaaaac tttagagacg tttttgaatt cgataattgg ttttttcaat
    11941 tggcataaat tccttctttt tcatagatta accgatcggg gctctgtcag gtccccacta
    12001 cctcttgcag ggagtaaaac cacctgcata catcttcgct accgataggc tttcacccaa
    12061 gatccggact tctctttcaa gcgtaatacc tgagtgttcc ttgacttttt cgataaccga
    12121 ttggatcaag tcctcgtagt ctttggccgt tccatctgcg acattgatca taaatcctgc
    12181 atgcttttct gacacttcta cgccaccgat acgatagcct ttcaagccag cttctgaaat
    12241 taactgacct gcaaaatgcc cgactggacg cttaaagacc gagccacaag atgggtattc
    12301 caaaggttgc ttgagttcac gtaggtgcgt caagcggtcc atttcctgct tgataacctg
    12361 atgggttcct ggagctaggg caaatttaac tgacaagaca actgcaccag actcctgaat
    12421 agctgaatgg cggtaaccaa aagccaagtc tttagcagac agggtttcga tttctccatc
    12481 cttggtcaag accttacaag actgcaagat gtgagcaatc tcgccaccat aggcacccgc
    12541 attcataaag acagcaccgc caacgcttcc tggaatacca caagcaaact caaagccagt
    12601 taaactatga cggagggcaa tgcgagttgt ttcaatcaag ttagccccag cttctgcttc
    12661 aatggtatag ccatcaacag aaacgttatt gagcttgtca cacaagatga caaatccacg
    12721 aatcccacca tcacgaacga tgatattgct tgcattgcca agaaccatcc aagggatatt
    12781 ttcttggttg gcaaatttca caacgcgagc caactcaaaa cgatttcgtg gaaagaccaa
    12841 ataatcagcc tctccaccta cttttgtata actatagcta tgcaagggtt ccttaaaacg
    12901 gatatcaatt ccttctaaga tttcaagcat tttttctctt acagacatgt cactcttcct
    12961 tttacaaaat tcattccatt ataccatttt tagagacatt tgacgaccat aaaaatacct
    13021 tgtttggatt ttgcataaga aaaagaggtt cccccctttt tatgattttt tacaaaagat
    13081 ttccttggtt ccataggcga ccagaacgag ctccagtgct agaatcactt caaccaagac
    13141 tggatttgtc aaccagccta cttggaaaag agatggtgcc agatcaaaga aggcatgcaa
    13201 gccataggct gctaggagat aaatccattt cttctggcga acagcttggt aaacccaaac
    13261 tgtcaaaagt aattggaaac caagcgccaa gattcgctca aaaccaagca aataaatctg
    13321 ccagaccgaa agtgactgaa tggtttttaa catattttca gacagtaatt gcataacctg
    13381 tggattctga gtttgaactg ccgaaagaac gatgtaaaga ttgagtaaac tagtaaggcc
    13441 tagaaaaatc aactccaagc caccatgccc taggccatag gccataggcc aaggcatctg
    13501 ccttttccaa acttctcttt ttctccaacc atttgaagaa aacaagacga gccgtttcct
    13561 caaaaaatgc tgccatggct aggccataga taatatagat aagcggatga tcttgcaaga
    13621 gggcaatact accgtctttt tgagggtgca aaatcaagat atgcaccagt ttttccaaaa
    13681 tctgcgaaga gacaaagaaa gcgactgcac ccaagcccaa gacagctaga ttaatctggt
    13741 atttcttttt ggcaaaccaa atgcttccta tcagaaaagc tagcaacagc aacatggtaa
    13801 taatgatatg aatggtcatt ttcttctcct attctgcctt ttcaatatct tttttcatct
    13861 cgtcaacatt gaacttagca aacaagtatt gacggtcttg gactgggaaa cgttggtcca
    13921 actggtcaac tgctcccacc tcgataatgc cttccttgat gacaaaatcc atgacatgtc
    13981 caccgaaggt caaatcatct gatatgaagt gcagatggta gcctgccaca ctgaccccat
    14041 ggaaaatctc aggcgtccag aaaccaacaa tagtccccgc aacattgtca cgactatatt
    14101 ccggttgatg ggttgcgaca tcagcaaact tggtatcggg tgttgactta ggaatcatac
    14161 gcacatgcat atgtaaaaat tccccccgaa tcttgataga gcggaaaaga ttttccccat
    14221 cataataaga ctcaattcgt tctttcaatt ccttgtctgt catctcaaag cgctggcgga
    14281 aaatgacctc tgcctgatgc ggtaccactg cagcgtaagg aataagggca tctggtgaca
    14341 cttccacaat ttctggctgg tctcctgacc ctttggcctg ataagccttg ccatccaaga
    14401 caatcaattc cccatcaatg gaatccaagg ttcccaaacc aaggtcacca tgttctagca
    14461 attctcctac tgtcatagta ccaccataaa ggccagccat caaggctcca agagtattgt
    14521 attgaaataa tttcactggt tcctgcacgt tcttatccat tcactttctt gtctgttatt
    14581 ctataaatct tactcctaag tataccacat ttgcccctag atgtgaacga gagaaacgct
    14641 ctagacattg ccaagaagga aaaaaaaggg tacaatgtaa caaaatcaag ggaggtctgg
    14701 aatgaagaaa caaagcaagt acaaagaggt cgtttcctat ctgaaaaatg gtatcgagtc
    14761 tgaacgattt ccgacgggta gtcgcctgcc ttctatccgt caactgagcc ttgactttca
    14821 ctgcagcaag gacaccattc aacgagccct gctggaatta cggcacgaac aatacctcta
    14881 tgccaagcct cagagtggct actatgtatt agaacaaggg caacatcaag acctagaaat
    14941 cgaggttacc gacgaacatg ccagtgccta tgacgatttc cgactctgtg tcaatgaaac
    15001 cttgattgga cgagaaaact acctcttcaa ctactatgac aatcaagaag gattagaaga
    15061 cctaagacag tccattcaca aactcctatt tgagcaagct ctctactgca aggctaacca
    15121 actagtactg acttctggaa cccaacaagc cttgtttatc ctctctcaaa tatcctttcc
    15181 tagacaagcc aaggaaatct tggtggaaca gccaacctac catcggatga atcgcctctt
    15241 gattgcacag gggctggact atcaaacgat tgaacgaggc attgatggga ttgacttgga
    15301 ggagctggaa ggccacttca aaacaggaaa aattaaattt ttctacacca ttcctagatt
    15361 tcactatcct ctgggacatt cctattctga gcaagacaaa cgatctattc ttaacttagc
    15421 tgccaagtat gatgtctata tcgtagagga cgattatctg ggtgatttgg actccaagaa
    15481 gggccaaacc ttccactatc ttgatacaga ggagcatgtc atttatatca agtccttctc
    15541 gaccagcctt tttcctgccc ttcgtattac agcactcatt cttccaaatg ctatcaaaga
    15601 agcatttgtg gcctacaaaa atatcctaga ctacgacagc aacctcatta tgcaaaaggc
    15661 cctgtcactc tatattgaca gtcaattgtt tgaaaaaaat cgtttggctc gcttgaccaa
    15721 tcatgaatct taccaaaagc aaatcgagga aaggataact aaaacacctt gtccccttcc
    15781 tcattatccc ctacacgatg gtttattgct agacctgaga cagtatccta aaatcgccag
    15841 tctcaaacac agtcaactgg gcttggactt ctttgaagag gcctatttaa gcacctgtcc
    15901 ttatcaattt gccaaggtgt ccctagacaa tctggaaaat gttttaaact atttaaaagc
    15961 agaattggaa tgacatccaa ctctgctttt tcttattctt caacttcagt tagacttgct
    16021 gctttttcaa gatagctttg gtaagttcct tcatccttaa gtttttggat aaccttgtct
    16081 accacttctt tcaaatcatc actatttttt ctaagagcaa cggcattggc gtcgccgtcc
    16141 ttcatcttca agctgacagt tgcgacagct aagccagcgt ttttagcagc ataactaagt
    16201 gcaacaggct catccatatg aacagcatct acttttccaa cctgcaattc attgactgct
    16261 tcacccatat tagttaggga agttaattga gcttttggca attgttcctt gaccattgat
    16321 tctggaacag tccctttttg ggctgcaata ttagcacttt ctaggctagt taaatccttg
    16381 tatttttcca catcagcctt acgaaccaag aaactaatct tgttttcata gtatgggatt
    16441 gaaaaatcaa agacttcttt tctctcgtca gtagcactaa ttcctgcaac tgctaggtca
    16501 gccttaccag tttgaagact ggtcaaaaca ttgtcaaaac tcatgcttga gatttccaac
    16561 ttaaccccaa gttcatcagc gatagcctga gccatgtcga tgtctgcacc gactacctgg
    16621 ttctttccat caaccaatga ttgaaattca aagggtgcat agtcaggact ggttgccaca
    16681 actaatttcc ctttttgttt gatagcatcc acagcagact gagaaccatt agaacctgac
    16741 tgacaagcta ctaagaagaa acttgcaaga aaattacata aaacaaatat ccattttttt
    16801 gatttcataa ataaacaacc tctctgttaa ttttgtataa ttataacgat atccaagtta
    16861 cttgtcaagt gttttttaaa tttttatctc aaaaatattt tttcgttcaa aaaaaggagc
    16921 catcagttga tttcaagctc ctttttatac agaattaaac tattttatag ttcgacaatc
    16981 ttacctgttt caaagtagac aacccattca cagatatttt tagcatagtc accgatacgc
    17041 tccaagtagg aaataacttg gaaataatca cgacccgtaa caatggcttc tggatttttc
    17101 ttaatctctt cagtcgcaag gtcacggata gtttcaaaat agtggttaat ttgctcatcc
    17161 atggaggcca cccggtatgc gtcgtcaaca gaaccattaa gataaagatc aagtgctgct
    17221 tcaacaacgc ttttaacttc acgtcccatt tttttaattt cttcctctac agctggaatg
    17281 cgctcttccc ccttcatacg gatggttgcc tgggcaatgg ctacagcgtg atcccccata
    17341 cgctccacat ctgatacagc cttaaggaca gtcaagactg tacgcaaatc ttgagagact
    17401 ggttgttgga gtgcgatcat ttcaaatgat ttcttttcca gtttcacttc gtattcattt
    17461 acttctgcat catcttcgat gacctctttt gccaggtcac ggtcatgcgt gacaaaagca
    17521 cgtaccgtac gattgatttg tgagagcact tcttgtccca tagcgtagaa ctggttatgt
    17581 aatttctcta aatcttcttc aaattgagat cgtaacatct ttcatctcct tatccaaatt
    17641 ttcctgtaat atagtcttcc gtttccttgt gttggggatc aaggaacatc tgcttggtat
    17701 cattaaattc aatcaaatct ccatctagga aaaatcctgt cttatcagag atacgtgaag
    17761 cttgctgcat ggaacgggtt accagaagca tggtgtactt gtcttttaga ccatacaagg
    17821 tttcctcaat tttaccagct gaaatcggat ccaaagccga agttggctca tccaagagga
    17881 tgattttagg actagttgcc aagacacggg ccacgcagac acgctgctgt tgaccacctg
    17941 acaatccaat agctgaatca tatagacgat ccttgacctc atcccagata gaggcacctt
    18001 gcaaggcttt ttctacggct tcatccagaa cctgcttatc cttaattcca ttgatacgaa
    18061 gcccgtagac aacattctca tagatagtca tagggaaagg attaggttgt tggaaaacca
    18121 ttccgatttc cttacgtaat tcaaccgtat ctgtacgcgg actgtagatg ttgtggccat
    18181 tgtacaccac ggatccagtt gtggtcacct ctggattgag atctcccatg cggttgagag
    18241 acttgaggag ggttgacttc cctgatccag atggaccaat caaggctgta atttccttag
    18301 gttggaaaga tagggaaaca ctattcaaag ccttcttttt attataataa acggacaggt
    18361 ctgatacctg taaaatcgca tctgtcatac ggtttccttt ctaaccaaag tgaccagata
    18421 catagtcatt ggtggactgt agcttggcat tttggaaaat agttgcagtc ttgtcatact
    18481 caatcaaatc acccaagtaa aagaagcctg tgtagtcact tgcacgagca gcctgctgca
    18541 tattatgcgt tacaatgatg atggtaaagt ttttcttgag ctcaaacatg gtctcttcta
    18601 gttgcatggt cgcaatcgga tccaaggctg aggctggctc atccattaag aggatatctg
    18661 gcttaacaga gatggcacga gcgatacaga gacgttgttg ctgaccacct gataaggtca
    18721 aggctgactt gtggagatcg tctttaacct gatcccagag ggcagcctga cgaagggagg
    18781 tttctacgat ttcatctagg acttgcttat ccttaactcc agcacgttca tgcgcaaagg
    18841 taatattacg gtaaattgac ttagcaaatg gattggggcg ttgaaaaacc attccaatgt
    18901 gtttacgcat ttcataaacg ttgatttctg gacggttgac atcaattcca cgatagagaa
    18961 tctgcccagt tactttagca atatcaatag tatcattcat gcgattgaga ctgcgtaagt
    19021 aggtagattt ccccgatccc gacggaccaa tcaaagctgt aattttattt ctttcaaatt
    19081 gcatatcaat ccccttaatg gattcatttt taccatagta aacatggaca tccttagtag
    19141 aaagggctac tttttcttca ggaaaggtaa ggatatgctt ctcatcccag ttatatgttg
    19201 acatggcttc tcctttaggc agcggttaat ttcttgtgta gatagcttcc gaacttacga
    19261 gctccaaagt taaaaatcag gataaagatc aggagcacag cggcagaacc tgctgataca
    19321 atggttccat ctggaatagt gccttcacta ttgactttcc agatatggac agccaaggtt
    19381 tctgcttgac ggaagataga gatggggcta gtcacactga ggatattcca gttagaccag
    19441 tcaagagctg gcgccgattg ccctgctgta tagatcagag ctgcagcttc gccaaagata
    19501 cgaccagatg ccaagacgac acccgttaca atacctggaa gcgcttctgg aataacaaca
    19561 tgaaccactg tctcccagcg agaaatccca agagccagac cagcctcacg ttgggtatgg
    19621 tgaacgtgtt tcaaactatc ctctacatta cgcgtcatct gaggcaagtt aaagactgtc
    19681 aaggccaagg cacctgaaat gattgaaaat ccatactcaa actggactac aaagatcaag
    19741 taaccaaaga gacccaccac cactgatggt aaagaggaca aaatttcaat acaagtccgc
    19801 acaaagttgg taacaggacc ttttttagca tattcagcca agtaaatccc agctcccata
    19861 gaaagaggta cagaaataat caaggtaatg accaatagga aaaaggaatt gtaaagctga
    19921 atgccaatcc caccacctgc ttgaaaagca gaagaccttc cagtcaagaa agaccaagag
    19981 atatggggca agccccgaac caagatatag agaatcaagg aagccaagat tgtcacaatg
    20041 atgctagcaa tcgtatagag gacagctgtt gcaagtttat ctaatttctt agcgcgcata
    20101 atttttcttt cctctttctt tcgtaatcaa tttaatcaca ctgttaaaaa ctaaactcat
    20161 caagagcagt accaaggcca gtgaccagag aacattatta tttacagttc ccatgacagt
    20221 gttcccaatt cccatagtta atatagaagt taaagttgca gctggtgtgg tcaaggaagt
    20281 tgggataaca gctgagtttc cgacaaccat ctggatagct agagcctcac caaaggcacg
    20341 cgccatccca aagaccactg cagtgaaaat accagaacgg gccgccttca agatcacacg
    20401 ccagatagtc tgccagcgag tggctcccat agcgaaactg gcttcacgat aataacgagg
    20461 aaccgcacgc aagctatccg ttgtcataaa ggttacggtc ggcaaaatca tgacaaagag
    20521 gacggaaatc cctgacaaaa tcccaaaacc agtcccacca aagacactgc gaacaaaggg
    20581 aacgacgact tgcaagccaa taaatccgta cactactgag ggaatcccaa ccaggagttc
    20641 aatagctggt tgcaaaatct tcgccccttt tggtgatact tcggtcataa aaactgctgc
    20701 accaatagca aagggtgttg cgataagggc tgagagaatg gtaacgataa aggaacccaa
    20761 aatcatagga agggcaccaa attctttact agaaggattc caagttcctc ccaaaagaaa
    20821 gtcaaagata ttcacaccat tgacaaagaa ggtcgacaag cctttttgcg ctacgaaaac
    20881 caaaatcatg gccacaagga tgactatcaa agaaagacag gcaaaggtca aaccttttcc
    20941 taatttctcc agacgagaat tctttgatgg aagcaacatt ttcttagcta attcttcttg
    21001 attcattatt gtctcccttc caacactgtc acagttccgg cagcatcttt ttcaaccttc
    21061 atttccttaa tcggaatata cttcaatcct ttgacaatcc cttcttgggt ctcatccgag
    21121 agaacaaaat tgagaaattc tgcagccaac tcattgggct gccccaatgt atacatatgc
    21181 tcataagacc acaagggcca attattgcta cttatatttt ctggacttaa gtcatagcca
    21241 ttcaacttca tgcttttgac cgaatcatct atataggtaa gagataaata agagatagct
    21301 cctggacttt ttgatacgat tgattttacc gctccatttg aatcctgctc ctgactttgc
    21361 atggcagact gaccttccat aatgacagta tcaaaggtag cacgagaacc agagccggct
    21421 gcccgattga taacagagat gggtaagtcc ttaccaccaa cctctttcca attggttacc
    21481 tcacctatga agatttgacg aagttgctct gtcgttaggt tatcaacatc aacctcctta
    21541 ttgacaatca gagccaagcc agctaccgcg accttgtggt caacaagagc agaagcatca
    21601 attccgtctt tttcctcagc aaatacatct gagtttccta tatcaactgc cccagactga
    21661 acctgggaca agcctgtacc agaacctccc ccttggacat tgaccgtttt tccaacatgg
    21721 atcgtgccaa attcatctgc cgctacttca accaagggtt gcaaggcagt tgagccaaca
    21781 gccgttatgg attctccacg atcaatccag ctagcacagc ctactaaaca agccgtcagc
    21841 caaaaagcga taagagacag agcaagcttt tttctttttt tcactgtttt tctcctcgaa
    21901 aataattatg aatactgtga attttttaag tagttcttta tgagttgacg catgaattct
    21961 taccaaattt ctgcgcaatt gattatttat ataatatagg ctatattact ctctcctaac
    22021 ctcctttttt catatgtgga taaaatctct tgtctatccc ttcccccatt gtcacccatt
    22081 atagtcattt cgtgtctctt tttccccttt ttaatgcaag ggaaattact ctccttagat
    22141 gataatccaa aagctagaaa ggtatctcaa acctctctac tctcccagac tagtttacaa
    22201 ctaaaaggaa aagattctat tttatgagaa atctagttta caagcggtaa gaacgctaat
    22261 aactaaactt cttgtactct ttgaaaatct cttcaaacca gtgttttgag ctatctatgg
    22321 ctagcttcct agtttgctct ttgattttca ttgagtagta aaactacatg taatggcaat
    22381 caagatatca agaatcatcc tactaaaaaa atccatactt tcactataac atagaataag
    22441 atatttgact agcattttca tttgaatctg aggccttttg gaaaataatt tttcaaaaca
    22501 tttccagtaa cctttgcaaa gcccaagcca ttgcctttaa ccaaaacttg gtaccaacca
    22561 tttggcagac tttctgccag ctgaacgatt tctccagccg catacttgac aaacgcttct
    22621 tggccaattt caaccgactg ttcgacctga ctcgatttca aggctaaacc aagagcgaaa
    22681 ctgggctcaa agcgtttctt cttaaaagta cccagatgca gtccattgcg agcaatcttg
    22741 agcttcccta aatctggcaa aagttctggc aagagataaa gctggtctcc aaaagtctgc
    22801 aagatacccg gtagattgac cttcaaatgg ttttgggcaa attcctgcca caaggcaact
    22861 tgttcacggc tgaggttact cttacttgcc ttaaatttag gagctggatt gttaccctta
    22921 aactgtagat gggcaacaaa ctgaccctct cccttaaact gatgagggta catccgagcc
    22981 gtttctggca ggtcaatacc agctaccatt ccattgatat gctctactgg caacaagtca
    23041 aaatcatact cttccagtaa ccaattgaca atctcttcgt tttcctcggg tgcccaggta
    23101 caggtcgaat aaaccagacg accaccttca gctaacatgg tcactgcatc ctccagaatt
    23161 tctctttgca agctagcaca ttgactcgga taatctaagc tccaatagtc catagcatca
    23221 ggttgcttac gaaacattcc ttcaccagag caaggggcat caagaacgat taagtcaaaa
    23281 tagcctttaa agaccttgac caagcggtcg gcagattcat tggtcaccac gacatttgtc
    23341 gctccaaaac gctccatgtt ttcaaccaaa atcttagccc gtttgcttga aatttcattg
    23401 gaaacaagta gcccctcccc tgctagatag gctgccagtt gagttgattt gccccccggt
    23461 gcagcagcca agtccaagac cttcatacca ggactgggtt gagctacttg agccaccatt
    23521 tgagcagcag gttcttgcga ataaactaaa cctgtagcat gctcaggcga tttccctgaa
    23581 accttcccat agtggcccca aggggtttga gtaatggcat cagaaaagga aagttgctct
    23641 tcttttaagg gattgacccg aaaggccgaa accgcttcct cctcaaaaga ggcaagaaaa
    23701 tctcttgcct catctcctag tatctcttta tatttttcaa caaatccttc tggaaattgc
    23761 atttaagttc ttttcctttc gtaaatatag gactgaattt cctcctgcat ctcaagaggc
    23821 accatcatga ccggctgtct ggtttgaaaa tcaggagctt caccaaaaag ggtcacaacc
    23881 cgatagccca gactttcccc taaaatacta gctgcggcat aatcccatgg ttgcagataa
    23941 gtgagatagg tcaacaaacg ccctgacaaa atcttggcaa aactaatggc cgcacttcca
    24001 tagacacgaa caccaagaac cgctcggctc aaatcagcca gcccccattc attggtttcc
    24061 agcataccac tattccctgc aatgagaaaa tctccaagtg gtttagtttt aaaaggagct
    24121 aggggcctat catttagaca aactggaaat tccccaccac cgtggtaaca atcccctttg
    24181 accacatcat aaatcagacc aaactgtccc tgaccatttt caaaataagc catcataaca
    24241 gcaaaatctt cctgctgggc tacaaaatta ttggtaccat caatgggatc aatgacccaa
    24301 accttgccct cttgaaccga ggctcgcaga caaccttctt cagcacaaat cttatcctca
    24361 ggataacggg acaaaatctc accaaccaag agttcctgaa cttctttgtc cagtctggtc
    24421 accaaatctg ttggagagga cttggtttca acacgcaagt cttcctgcat atggtcaaga
    24481 atgtactgac ctgctttctt aacaagctct ttagcaaatt caaatttact ttccaagaga
    24541 aatctttcct tccccttttt ctttggcagc ctgaactgct cggtaaagtg aatagccact
    24601 aaccgtttca aattctcgtc ccaaacgttt ctcttcgctc ttgcttggca cgaccgcttt
    24661 gaatccctta taggagtcca gtaacttttt agcctctact ttgccttcat aggcagcttc
    24721 aacatcatta aaaaaagaaa gcactgaagc aagttcttca gtgctccacg acaaatctag
    24781 tgggtaacta tactgtttgt tcattaacta ataccagctc tcattcttgc ttcttttagt
    24841 tcttgcttac gataactacg agggagaaaa gcacgaatct catcttcatt aaaaccgatt
    24901 tgcatacgct tggcatcaat aataattgga cgacgcaaaa gactaggata ctgctcaatc
    24961 aaatgaagca attccgatac cgaaatactc tctacatcaa tattcaattt ttgaaaaatt
    25021 tttgaacgag ttgaaatgat gtcatcagta ccattttcgg tcaaggaaag gatgtgttgc
    25081 aattcttttc ttgttaaagg actggtcata atattgtgtt ccacaaaggg aaccttatgt
    25141 ttttctaacc aggccttagc cttacgacat gatgtacagc tcggtgatag aaatagtgta
    25201 atcatgcttt tctcttctta tctatacttt gctacttcta ttatacaaaa aaataaggcg
    25261 cttgactagg gatttttaga aaaaaagcct attttttcaa gaaaaatagg ctgtttgcga
    25321 acgattgaca caattggatt tggttaattc actcttaacg atggttttaa acgatatata
    25381 tttttatata tgcaaattaa aaacatcttt catttcactt cctacgactt ttcagacaca
    25441 gatagccaaa gaagctttca tagagggcaa aaaagaggag gaaggcatga agaaagaagg
    25501 tctctggcaa aatcataata acaggatcct tggctggatc aaaaagccag gtatcatctc
    25561 ccacaaagag aatttgatgg aaaagagtaa agaattggtc aaaaccaatc aaaactcccc
    25621 caagtccaat catcacaggt aagactacta gagccaggag actttttcga taaagagaca
    25681 aaaagtcctt tttcacaatc ctattgacaa agacatagaa acttggcagt gtcactagag
    25741 ctactagctg aaccaaatga aagagattct tgaccactgc gaaatggtgc agaccagctg
    25801 ctgacgaacg aaaatcaggc atctgtaaga cctgactaaa aggattggtc agataattca
    25861 tcaagatatg aaaattgtat tgaatggttt ctggttttag atagactcga ttcgttaagt
    25921 ttagccactg aatctccata ggatagaaaa tccaagccag ataaatggtc agaaggattg
    25981 agagggagag gagaaagagc atagagcccc aaaaggtcaa tttagttttc atcaaaatcc
    26041 cactccgcaa ggctagaaac cacatgtgtc ggtgcgattg gcaggccagc tacttcttct
    26101 gccttggtaa aacctgtcgt caccaagagc gttggaatgc cattgtcaat cccagcccgg
    26161 atatcagtca aataattgtc cccaaccatg attaactctt cacgttccaa acctaagtgc
    26221 tcaaccgcct tgtccataat gatggcattt ggttttccga tataaaccgg cttcactcgt
    26281 gtcgctactt caagcagcgt aatcagtgag ccagcacctg gcaaaagacc gcgttccgtc
    26341 gggatgttga ggtcaggatt ggttccgata aaatgggcac ccttttgaat agcaagagtt
    26401 gctgtggcaa atttttcata gtcgacttgc caatccagac caactaccac gtaggcaggt
    26461 ttttccttgt cttccacata accagccgcc ttgatggctt ccttgagtcc tgcttctccg
    26521 acgacataga cggtcttttc aagccccaaa tcattcatat agtcgatggt tgccaaagtc
    26581 gctgtgtaga cagtcgatag gggcgtatcg atattaaaat tctgagccaa catctcctta
    26641 acactctctg gagtgcgggt tgtattgttg gttacaaaga gatagggaat gtcccgcttt
    26701 tgcaattcat gaacaaaagt ctctccagca gggattcggt ctttcccctt ataaatggtt
    26761 ccgtctaaat caattaaata gcctttatat ttcatctatt tctccctaag ccttttttat
    26821 ttcttgccaa gtaatgattg cttgggcatt gataacccca tcacttgtaa tttcatgctt
    26881 gctttccagt ccagtccgtt caacagccga tgtaatcacc ccacctggtc gaacttcctt
    26941 gacatacttg aggttgattt tcttgggaat atagtgggtc aaaaaatccg ctcccatgac
    27001 ctcaaaaatc cagtccaagt atttactgtt attgacatga ccattcatat ccaagtcgta
    27061 aaaacgaaca tggtaatcct tgctgatcgg ttcttccaag gactcatact tcggtccacg
    27121 gataagtttt ttatcaaaat cagactggta aggagccaca atctcaggtt caacaacatg
    27181 gacttttcga ctgtcgcggt ccatgagaac aaaggtcgcc atcatgtgga tgagctcctg
    27241 ctccgcttca ttataaatag taaagcgacg gtagcaaaaa agtcgattgt agctcaaggc
    27301 ttccgtttcg atggtaattt cttccgcaaa acgaggcaaa cgaaccacct caatatcata
    27361 ttctacgata atccagacca gattatattc ttccaaaatg gccttatcac taactcccag
    27421 ttcaatcgac tgcatccctg aaacttgcag tgacagcaaa atcacatctg gaagtttgat
    27481 atgaccgttc atatcagcca tatcaaaagg aattttcatt ttcatttgat aagttaagcc
    27541 catgatccta ctccaaaata aatcgttctg ctacagtatc tcccaaaaag agacctctct
    27601 ttgtcatgcg aacgtggtca ccctcaatct gcatgaggcc ttgttgaacc aaatctctga
    27661 caatttctcc ataaagtcca gcaaaagact gtccaaattt ttcctcaaat cgcgccatgg
    27721 aaaccccgga tttcttgcgg agtcccaaga acatttcttc ttccatttgc tccttttgac
    27781 tcaggtgatc ttctgtaata caagcattgc cttcctcaac cgcactgaga taatgacgaa
    27841 tgggaccatg atttttatag cgtactccat tgacataacc agatgcccct gcaccaatac
    27901 catagtattc agcattgtcc cagtacatga gattgtgacg actttcaaaa ccgggtttgg
    27961 agaaattaga aatctcataa tgctcaaaac ccgctcgctc cagctctgca atgatgtact
    28021 caaacatctc cgcttctagt tcctccttag gcagaggcaa tttcccacgt cgcatccggt
    28081 tcataaagac cgtatggttt tctaaaatca aactatacaa actcatgtgg ggaatatcca
    28141 gtccaatggc tttagccaca ttttccttta cttgctccat ggtctgacca ggcagagcat
    28201 aaatcaaatc aatggagatg ttgtcaaaac cagccagttt cagacgatcg atattttcat
    28261 aaatatcctt ctccaaatga ctgcgcccaa tctttttcaa catcttatca tcaaaggtct
    28321 ggacacctag cgaaacacga ttgacagccg aatttttcaa aacagctatc ttatccgcat
    28381 ccaaatcgcc tggattggct tcaatggtca actcttccaa gacagacaag tccaagtttt
    28441 tagtcaagcc attcagtaac acctccagtt gcggagccga cagggctgtc ggtgttccac
    28501 caccgatata aagggttgac aacttttcaa tatcataaga acgaaactct tccagcagat
    28561 gctctaaata gctgtcgact ggctgatttt tgatgaagac ctttgaaaaa tcacaataat
    28621 aacaaatctg ggtacaaaat gggatgtgca cataggctga cgttggtttt ttctgcatag
    28681 taattattat accacaaaga ctagattcca gataaaaatc accatcccca gatacatagt
    28741 ccgtccggag atggtgatgg tttattcttc tgttatatca atcacaatct cttctgagtc
    28801 atcaagagct tcggcttttt cttgccattg ttccttgaga ttatttaatt gattttttga
    28861 tgcttctgtc gcttgaaaag cataggattt agcttgagca agtatactat ccacagtgat
    28921 ttcacctgac tcaacctgtt cttttgtttt cagaacaaaa tctgtagcct gctccttaac
    28981 ttctgtcagt ttttcacaga cttgctcctt ggcatactcc ggatcttctc tcaaatcatc
    29041 tagaaaatct tgagcctgac tgcaaacttg tttgccctta tcacttgtta aaaacaaggc
    29101 aagagctgca cctgaaaccg ttcctaaaag gattgaggat aatttaccca taaggattct
    29161 ccttttttat tttttgaaaa atttacttgc aagacgaaga gctgacagac ttgcaccagt
    29221 cttgagtgtt tttgaaccag ctgatgaagc tttcttgctc aagacacgcg catggtcatt
    29281 gaggtctgaa acagatagag ataaatctgc aacagcgctg aagagtggat caatcgtagc
    29341 caccttgaca ttgatatcat ctgccaagac attgacctta gccaacaact cattggtgtg
    29401 atgcaaggtc acatccacat ctgaagtcaa ggttttaatc gtcttttctg tttcatcgat
    29461 gacacgacca agcttttgta cagtaatgat cagatagacc aaaaagacaa tcaaagctag
    29521 ggcaacaaga atatatgcaa cttctaacat ttatttttcc tcctctgtaa tatagtaagg
    29581 ggccttcttt cgattttgat aaataacgat cattataccg agaccgataa ggacaactga
    29641 cagccattgg gacactcgaa ggctgaagaa catgagacta tctgttcgca taccttcgat
    29701 gaccatacga ccgaaaccat accaaatcaa gtaaaaggcc gtgatatgac ctcgtctgag
    29761 actcttccat ttccgtctaa aaatcagaat caaagcaaag ccaagcagat tccatagaga
    29821 ctcataaagg aaagtcggtt gacggtagct cccctcaata tacatctggt cacggataaa
    29881 gccaggtaga taatccagat tatccactgt tgcaccataa gcttcttggt taaagaaatt
    29941 accccaacgc cccaaacttt gagcaatcat aacgctaggc gccgcaatat ctagaaaatc
    30001 ccaagtattg atgagtttac ggtcagcaaa gatatagagc acaagagccc cagttatcaa
    30061 accaccgtaa atggccaaac caccattcca aatggcaaaa atctctccta aattctgact
    30121 atagtaatca aatcggaaaa taacatagta gagacgagct cctaaaatag ccaagggaaa
    30181 ggctactaag ataaaatcta aaatatcgtc tggtatgatc ttctttctag gtgcttcttt
    30241 catggtcaaa taaaccgcaa gaatcaagcc tgtcacaata cataaggcat accaacgaat
    30301 ggctaggggt cctagttgaa tagcaattgg atcaagcatt ttgcacctca tttcgagcaa
    30361 tgagacttgt cagtcgttcg tcgaacaaac gggtcgcatc aaagcccatt tccttggcac
    30421 gataattcat ggcagctgcc tcaatcacaa cagagatatt acgacctgtt ttaactggaa
    30481 tacgaatacg aggaatggct acgccagaaa cttcaagttc ctctgcattg tttccaagac
    30541 gatcaaaggt cttatgtgta tcgtaatttt ccaaatagac agcaagctga acctgtgaag
    30601 aatccttgac agcactcgca ccgtagagac tcataacatc gataatacca accccacgaa
    30661 tttcaatcaa gtgtttcaaa atttcagctg gttcacccca gagagtaatc tcatccttgg
    30721 caaagatatc gacacggtca tcggctacca aacggtgacc acgtttgaca agctcaagac
    30781 ctgtctcgct cttaccaatt ccactatctc cctgaatcaa gacgcccatc ccataaatat
    30841 ccatcaagac accgtgcaca ctggtacgtt ctgccaaacg agaatccaga tagctagata
    30901 actctccaga taaacgactg gtagctgcac ggctggttaa aatagcaatc ttacattctc
    30961 tagcagcctt taacatctcc tctggaacca ccaaaccacg agcaacaatg actgctggtg
    31021 tctcaggtag aaacattttt ttcaaaactt cataacggct gttggaaggc atgctgatca
    31081 gataagacca ctccttcatc cccaaaagtt gaatccgctc tggtgtatag tagtcaaaat
    31141 agcctgtcat ttcaagacca ggtcgcgtaa tatccgctgt attgatttcc ttttcaagca
    31201 actctggttc accatagaca atgtctagtc taagcttttc aatcacttct tttactaaaa
    31261 ccgacatcat ttcctccttc aaatgagttc ttctctctat tatatcaaat tgtaggagga
    31321 agtttcagat ttttgcaggc tttggagtat ttatttaaaa gaaaaaggac tagatttctc
    31381 tagcctttca tttcaattag aattttttac gtttacgagc tacttctgat ttacgtttac
    31441 gttttacaga aggtttttca tagaattcac gtttgcgtgt ttcttgaaga gtaccagctt
    31501 tagtaaccgc acgtttgaaa cggcgaagtg cgtcgtcaag agattcattc ttacgtacta
    31561 ctgttttaga catttttttc actcccttca agttcaatat ctatttcatt ctacacgtaa
    31621 aaggaataat tgtcaagcaa aaatgcggtt taattttgat tttttcttcc atttatacaa
    31681 gagttgaaag cgttcaatag aacattgctt ttttattttt cgagtaagct aagcgcttca
    31741 gcatctgcga tgatggttac atcagggtga ttttgaaggc tacttgcagg taggttctca
    31801 gtcactgggc cagatactgt tccggcaatg gcttctgctt tcgactcacc gtaagcaaaa
    31861 agaataatag acttggcatc caaaatgttt ttaatcccca ttgaaatagc ttgggttggg
    31921 acgtcttcaa tcttggcaaa gaagcgtgca ttggcttcga tagtagactg gtcaagttct
    31981 actagatgcg tttgactgtc aaatggagta ccaggctcat taaagccgat atgcccattg
    32041 cgaccgattc ccaagatttg gaggtcaact ggatggtcag ccaaaatttg gttgtagcgt
    32101 tcaacttcag cttcagcatt gtccttaaca ccacgaggca agaaactttc tttaaatggt
    32161 ttttggttga acaagttttc ttgcatgaag taacgataag actgtggatt gtccccatca
    32221 aggcccacat actcatcaag gttgacactg gttagatttg aaaaatcaag gtcactctca
    32281 acaatttcct tgtaaaattc aagtgggcta cttcctgtcg caagtcctag agtttgagct
    32341 ccattagcca atttttcctt caaaatctca aaagcaactt ttccaccttg aacttggttt
    32401 tcaactttaa taactttcat cttttcatcc tccatttctg tctatattta ttatatggta
    32461 tagaccaatt tttgtcaagt gaaaacgatt taatttctaa aaaaagagcg tccaaacttg
    32521 aaacgtgtta taatggatag gattataact tagaaagaat gaacaaatat atgaatacag
    32581 ctgattttga tttccacttg ccagaggaat tgattgccca aacgcccctt gaaaaacgtg
    32641 atgcctccaa actcctcatc gtcaaccgtg agacaggaga aatgcaagat aaacatttcc
    32701 actctattat tgatatgctg gaacctggtg atgcccttgt catgaacgac acccgagttc
    32761 tccctgcccg cctctatggt caaaaagtgg agacaggagg tcatgtggaa cttctcctcc
    32821 ttaagaacac tagtggagac gagtgggaag ttctggctaa acctgccaaa cgcctcaagg
    32881 tcggtactcg tatcagcttt ggtgatggcc gcctcagcgc tgtcgttaca gaagaattga
    32941 cccacggggg acgcattgtc cgctttgaat accaaggaat tttcctagaa gtcttggaaa
    33001 gtctgggaga aatgcctctg ccaccttata tccacgaaaa attagatgac cgtgaacgtt
    33061 atcaaaccgt ctacgccaag gaaagcggct ctgctgcagc accgactgct ggtcttcact
    33121 tcaccaaaga actgctggca gaaatccaag ctaagggtgt tcatctagtc tatctgactc
    33181 tccatgtcgg actcggaacc tttagacctg tttctgtgga taatctggac gaacacgaaa
    33241 tgcactcaga gttctatcaa ctttctgagg aagctgctgc cacccttcgc tctgtcaaag
    33301 aaaatggtgg tcgcgtcatc gctgtcggaa ccacttctat ccgcaccttg gaaactattg
    33361 gttccaagtt tgatgggcaa atccaagcag attctggttg gaccaatatc tttatcaaac
    33421 ctgggtatga gtggaaggtc gtggatgcct tctcaaccaa cttccatctg ccaaaatcaa
    33481 ctctggtcat gttggtttct gcctttgcag gccgtgaatt agtcttagat gcctaccacc
    33541 atgccatcca agaacactac cgcttcttca gttttggtga cgccatgttt atttattgag
    33601 aaagaatttc tctaattctt ctaataccaa taaatcgcta agatattatt tcaaagaaca
    33661 tctacaattg aaactctagc tagctgtaga agacgcctag tacattgaaa ttaaaatgct
    33721 tccccctagc ttcgaaaata ttgccataga ttgcgttgac tctccaaatt gattcatcta
    33781 tattttattt cagcttccta tattttcttc gctgtttgta aatcaaaatg caagacacat
    33841 gagtagcacc atatttgtta ctcttatctg tcctctcaag agactattat gagttatttc
    33901 agaatcattc actactttga ccctgactct ccttagtctc aaaatcaaag acttatactc
    33961 ttcaaaaatc tcttcaaacc gcgtcaacgt caccttggat tatatatgtg actgacttcg
    34021 tcagttctat ctacaacctc aaagcagtac tttgagcaac ctgcgactag ttttctagtt
    34081 tgctctttga ttttcattga gtattaaaca aaaagtgaac aaatctgaat tctaatgtac
    34141 agaagactag gcttgttcac ttttttatag tcgctataag atgaccttat ctatagcttt
    34201 ttatatataa ttatatattc agacatacta ttatcaattt tgtcgcaggg aggaatctgt
    34261 taacgcaccc attcaccatt atcattgact ctatagccat ctatacttgt attgaccgct
    34321 aactcacccg atgcatttac ataataccat ttaccaccaa cttggaacca ttgattgact
    34381 ttcatagaac cgttgctgtt gaggtagtac catgaaccat taacttgtac ccaacctgtt
    34441 gccatggaac catcagtatt ataaaaatac cacataccat tttcttgttt ccagtctgtt
    34501 gttggagcaa ctgctttagc tggttctact gctacatctg ttccttggtt agatgtaaca
    34561 gatacaggat acgaaggaat agatgattgc tcaggaacaa caactttttc aggttctctc
    34621 gtccctctcc ttatacgtct ttttaccatc tctttagtaa tttgacgaga agtagtttct
    34681 tcaattgttc catcacgttc atctacagta tagattgtag taagagtaat ttaccaattt
    34741 ctcctacttc ttctacttct tgacttttat caagagttgg gccatcgaga tattctgttt
    34801 cgattggaat ttcttggaca agaacttggg gcttggttct ttttttaaca actcttgttt
    34861 gagagtcttt ttttgactta aagtactctc agttacttgt ccactctttc catctacatt
    34921 ataagttatc gttgtaactg ttttcccatt ctttcctaga gtaatctctt gctcctgtcc
    34981 tgcagaaagg tcattgtctg cttcatattt agtagcaaat ggaacaagaa cttcttcaac
    35041 cttgctttta gctggaactt tgataactgt atccgtggct tcttttctat caacagtaac
    35101 ctgttcggta acataaccag tctctggatt aacatcgtag gtccttgtcg tagttacata
    35161 gccatcctct ccatcaattg taacaggatt ttcactacgg tcttttgttt catctttttc
    35221 ataacgaatt cgcgtacttg aaattttctt ggttactacc ttaggtttag tcgctacttt
    35281 tacaataata tccccattgt cagcgtcatc atactctatt ccctcttctt tatctctagt
    35341 atcatctctg acatattgaa tcccatcagc agcatgaaca aaacttgtat tcagattcct
    35401 cctaaaaata aagttagccc gattaccgca gaaccaaaaa tctttccgag tttacgtatt
    35461 gcatagcgct tattagtatt agattttgcc attacatcct acttctagta tagcatcttt
    35521 tctatcaaac gttaaacaat atactttata tataaaatag acttagaatg atatattgat
    35581 tattgaacta acactttaac tatatcgtaa tcaatctcat atataaagga ttgcagacat
    35641 cttatc
//
LOCUS       DAVLTG010000018        34418 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLTG010000018 DAVLTG010000000
VERSION     DAVLTG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.018"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            546..998
                     /locus_tag="VYN12_000930"
     CDS             546..998
                     /locus_tag="VYN12_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1415340.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1017..2354
                     /locus_tag="VYN12_000931"
     CDS             1017..2354
                     /locus_tag="VYN12_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1415341.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2433..3317
                     /locus_tag="VYN12_000932"
     CDS             2433..3317
                     /locus_tag="VYN12_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1415342.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3317..4150
                     /locus_tag="VYN12_000933"
     CDS             3317..4150
                     /locus_tag="VYN12_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1415343.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4168..6261
                     /gene="nanB"
                     /locus_tag="VYN12_000934"
     CDS             4168..6261
                     /gene="nanB"
                     /locus_tag="VYN12_000934"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1415344.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRVESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6273..7376
                     /locus_tag="VYN12_000935"
     CDS             6273..7376
                     /locus_tag="VYN12_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1415345.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
     gene            7550..8248
                     /locus_tag="VYN12_000936"
     CDS             7550..8248
                     /locus_tag="VYN12_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1415346.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8267..9784
                     /locus_tag="VYN12_000937"
     CDS             8267..9784
                     /locus_tag="VYN12_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1415347.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9909..11237
                     /locus_tag="VYN12_000938"
     CDS             9909..11237
                     /locus_tag="VYN12_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1415348.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11489..12355
                     /locus_tag="VYN12_000939"
     CDS             11489..12355
                     /locus_tag="VYN12_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1415349.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12371..13210
                     /locus_tag="VYN12_000940"
     CDS             12371..13210
                     /locus_tag="VYN12_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1415350.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13483..13935
                     /locus_tag="VYN12_000941"
     CDS             13483..13935
                     /locus_tag="VYN12_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1415351.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            14032..14376
                     /locus_tag="VYN12_000942"
     CDS             14032..14376
                     /locus_tag="VYN12_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415352.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14660..15304
                     /locus_tag="VYN12_000943"
     CDS             14660..15304
                     /locus_tag="VYN12_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1415353.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15473..16390
                     /locus_tag="VYN12_000944"
     CDS             15473..16390
                     /locus_tag="VYN12_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1415354.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLDTARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16408..17292
                     /locus_tag="VYN12_000945"
     CDS             16408..17292
                     /locus_tag="VYN12_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1415355.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17308..18159)
                     /locus_tag="VYN12_000946"
     CDS             complement(17308..18159)
                     /locus_tag="VYN12_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1415356.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18359..20416
                     /gene="pbp2b"
                     /locus_tag="VYN12_000947"
     CDS             18359..20416
                     /gene="pbp2b"
                     /locus_tag="VYN12_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1415357.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKVTTSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVPTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTAFSRPMPITAVQALEYSSN
                     AYMVQTALGLMGQTYQPNMFVGTSNLESAMGKLRSTFGEYGLGSATGIDLPDESTGFI
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSVLHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20427..21023
                     /gene="recR"
                     /locus_tag="VYN12_000948"
     CDS             20427..21023
                     /gene="recR"
                     /locus_tag="VYN12_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1415358.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPVGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21199..22242
                     /locus_tag="VYN12_000949"
     CDS             21199..22242
                     /locus_tag="VYN12_000949"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1415359.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22326..23699
                     /locus_tag="VYN12_000950"
     CDS             22326..23699
                     /locus_tag="VYN12_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1415360.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGVELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23722..24297
                     /locus_tag="VYN12_000951"
     CDS             23722..24297
                     /locus_tag="VYN12_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1415361.1"
                     /translation="MIALTDTGLTFTKEPFDRERYEDLRSLLSEMLNQVSDLDADEVA
                     ELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEVGYSPTENILKEI
                     EEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQENQEIADLQFFAID
                     QLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24388..25092
                     /locus_tag="VYN12_000952"
     CDS             24388..25092
                     /locus_tag="VYN12_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1415362.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25311..26684
                     /gene="ftsA"
                     /locus_tag="VYN12_000953"
     CDS             25311..26684
                     /gene="ftsA"
                     /locus_tag="VYN12_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1415363.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26701..27960
                     /gene="ftsZ"
                     /locus_tag="VYN12_000954"
     CDS             26701..27960
                     /gene="ftsZ"
                     /locus_tag="VYN12_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1415364.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27965..28636
                     /locus_tag="VYN12_000955"
     CDS             27965..28636
                     /locus_tag="VYN12_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1415365.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28646..29185
                     /locus_tag="VYN12_000956"
     CDS             28646..29185
                     /locus_tag="VYN12_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1415366.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29185..29448
                     /locus_tag="VYN12_000957"
     CDS             29185..29448
                     /locus_tag="VYN12_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1415367.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29445..30230
                     /locus_tag="VYN12_000958"
     CDS             29445..30230
                     /locus_tag="VYN12_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1415368.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30239..31027
                     /gene="divIVA"
                     /locus_tag="VYN12_000959"
     CDS             30239..31027
                     /gene="divIVA"
                     /locus_tag="VYN12_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1415369.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31375..34167
                     /locus_tag="VYN12_000960"
     CDS             31375..34167
                     /locus_tag="VYN12_000960"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1415370.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10566 a         6082 c         7507 g        10263 t
ORIGIN      
        1 agagaatgaa atatagagta tttctctctt aaaagttttt ggtgaaacga gatgtagaaa
       61 ggagatttag ccaaagagtc tattagtgct agaataatag attagaatta ttttagaaaa
      121 acgaagtgag cagcttataa attcaagtcc ccaaatagat tcatactagt atcttttgca
      181 aaaaataaag ggcgacttcc ttcatgaata tcaatttcat ctataaggaa ggtagctaat
      241 tgaactaact tatttattct gtttgtcgct agaaaaatca gacctccttg tgaagattga
      301 ggagatactg aatgaaaatc aaagaagaaa ctagcaagct agtagcagat tgcccaaaac
      361 accgctttga ggttgtagat aagactgacc tatataatcc aaggtgaagc gactgtggtt
      421 tgaagagatt ttcaaagagt ataggctaga gagtagtgtt tttatgtcct tctagtagaa
      481 aatgctagac agaagaatgg ggaacttgga taggaaaaat agattgagaa aggaggttag
      541 aagagatgat tattacaaaa attagccgtt taggaactta tgtgggagtc aatccacatt
      601 ttgcaacatt aatagatttt ctagaaaaaa caggactaga aaatttaaca gaaggttcga
      661 ttgctatcga tggtaatcga ttgtttggga attgctttat ttatctagca gatggtcaag
      721 caggggcttt ctttgaaaca caccaaaaat atttggatat tcatttagtt ttggaaaacg
      781 aagaagccat ggctgttaca tcgccggaaa atgtaagcgt tacccaagaa tatgatgaag
      841 agaaagatat tgaattatac acagggaaag tggaacagtt ggttcatttg agagctggtg
      901 aatgcctcat cacttttcca gaagatttac atcaacccaa ggttcgtata aatgatgaac
      961 ctgtgaaaaa agttgtcttt aaagttgcga tttcttaatg tagaaagaga agaacgatga
     1021 aaaaaatgag aaagttttta tgtctagctg gaattgcgct agcggctgtt gccttggtag
     1081 cttgttcagg aaaaaaagaa gctacaacta gtactgaacc accaacagaa ttatctggtg
     1141 agattacaat gtggcactcc tttactcaag gaccccgttt agaaagtatt caaaaatcag
     1201 cagatgcttt catgcaaaag catccaaaaa cgaaaatcaa gattgaaaca ttttcttgga
     1261 atgacttcta tactaaatgg actacaggtt tagcaaatgg aaatgtgcca gatatcagta
     1321 cagctcttcc taaccaagta atggaaatgg tcaactcaga tgctttggtt ccgctaaatg
     1381 attctatcaa gcgtattgga caagataaat ttaacgaaac tgccttaaat gaagcaaaaa
     1441 tcggagatga ttactactct gttcctcttt attcacatgc acaagtcatg tgggttagaa
     1501 cagatttgtt aaaagaacat aatattgagg ttcctaaaac ttgggatcaa ctctatgaag
     1561 cttctaaaaa attgaaagaa gctggagttt atggcttgtc tgttccgttt ggaacaaatg
     1621 acttaatggc aacacgtttc ttgaacttct acgtacgtag tggtggagga agcctcttaa
     1681 caaaagatct taaagcagac ttgacaagcc aacttgctca agatggtatt aaatactggg
     1741 ttaaattgta taaagaaatc tcacctcaag attctttgaa ctttaatgtc cttcaacaag
     1801 ctaccttgtt ctatcaagga aaaacagcat ttgactttaa ctctggcttc catatcggag
     1861 gaattaatgc caatagtcct caattgattg attcgattga tgcttatcct attccaaaaa
     1921 tcaaagagtc tgataaagac caaggaattg aaacctcaaa cattccaatg gttgtttgga
     1981 aaaattcaaa acatccagaa gttgctaaag cattcttaga agcactttat aatgaagaag
     2041 actacgttaa attccttgat tcaactccag taggtatgtt gccaactatt aaggggatta
     2101 gcgattctgc agcctataaa gaaaatgaaa ctcgtaagaa atttaaacat gctgaagaag
     2161 taattactga agctgttaaa aaaggtactg ctattggtta tgaaaatgga ccaagtgtac
     2221 aagctggtat gttaactaac caacacatta ttgaacaaat gttccaagat atcattacaa
     2281 atggaacaga tcctatgaaa gcagcaaaag aagcagaaaa acaattaaac gatttatttg
     2341 aggctgttca gtagatgtaa aagactagaa aataggtggg ctagtgagct gaaaagctct
     2401 agcccaatct tgtaaaagaa gggagaagga gaatggttaa agaacgtaat ttaactcgct
     2461 ggatatttgt tttgccagct atgattatcg taggattact ctttgtttat ccgtttttct
     2521 cgagtatttt ttatagcttt accaataagc atttgattat gcctaattat aaatttgttg
     2581 gtttggctaa ctataaagct gtgctatcag atcccaactt ctttaatgcg ttctttaatt
     2641 caattaagtg gaccattttc tcattagttg gtcaagtttt agtagggttt gtattggctt
     2701 tagctcttca cagagtacgc cacttcaaga aattatatag gaccttattg attgttcctt
     2761 gggcatttcc taccatcgtc attgcctttt cttggcagtg gattctaaac ggggtttatg
     2821 gctacttacc taatctaatc gtaaaattag gtttaatgga acatacacct gcatttttga
     2881 cagatagtac atgggcattc ctatgtttgg tgtttatcaa catttggttt ggagcaccaa
     2941 tgattatggt taatgtgctt tcagctttgc aaacagtacc agaagaacaa tttgaggctg
     3001 ctaagataga tggtgcttca agttggcagg tgttcaagtt tatcgtcttt ccacatatta
     3061 aagtggttgt aggacttcta gttgttttga gaactgtatg gatctttaat aactttgaca
     3121 ttatctacct cattactggt ggtggaccag ccaatgctac aacgacgctt ccaatttttg
     3181 cttacaacct gggctgggga actaaattgt tgggtcgtgc ttcagcagtt acagtattgc
     3241 tctttatctt cttggtggcg atttgcttta tctactttgc tatcatcagt aagtgggaaa
     3301 aggagggtag aaaataatga agaagaaatc cagtatttat ttagatattc tctcacatgt
     3361 acttttagtt ggtgcgacca tcgttgcaat tttcccattg gtatggatta tcatatcttc
     3421 tgtcaaaggg aaaggggaat taactcagta tccaacacga ttttggcctg aacagtttac
     3481 attagattat ttcactcatg ttatcaacga tttgcacttc attgataaca ttcgaaacag
     3541 tttaatcatt gccttggcta caaccctcat tgcgattatt atttctgcta tggcagccta
     3601 tggtattgtt cgattctttc ctaaattggg agcaatcatg tcgagactac tcgtcattac
     3661 ctacattttc ccaccaattt tgttagcaat tccctattca attgccattg ctaaagttgg
     3721 gttaacaaat agtttatttg gcttgatgat ggtttatcta tcttttagtg ttccatatgc
     3781 agtttggctc ttagttggat ttttccaaac agttccaatt ggaattgaag aagcggctag
     3841 aattgatggt gcaaataaat ttgttacgtt ttataaagtt gtgctaccga ttgtagcacc
     3901 aggtattgta gcaacagcta tttatacatt tatcaatgct tggaatgaat tcctgtatgc
     3961 cttgattttg attaacaata caggaaagat gacagtagca gtagcccttc gttcacttaa
     4021 tggttcagaa atactagact ggggagatat gatggcagcg tctgttattg tagttcttcc
     4081 atcaattatt ttcttctcta tcatccaaaa taagattgca agtggattat cagaaggatc
     4141 tgtgaagtag acgaaagaag gaaaaaaatg aataaaagag gtctttattc aaaactagga
     4201 atttctgttg taggcattag tcttttaatg ggagtccccg ctttgattca tgcgaatgaa
     4261 ttaaactatg gtcaactgtc catatctcct atttttcaag gaggttcata tcaactgaac
     4321 aataagagta tagatatcag ccctttgtta ttagataaat tgtctggaga tagtcagaca
     4381 gtagtaatga aatttaaagc agataaacca aactctcttc aagctttgtt tggcctatct
     4441 aatagtaaag caggctttaa aaataattac ttttcaattt tcatgagaga ttctggtgag
     4501 ataggtgtag aaataagaga cgcccaaaag ggaataaatt atttattttc tagaccagct
     4561 tcattatggg gaaagcataa aggacaggca gttgaaaata cactagtatt tgtatctgat
     4621 tctaaagata aaacatacac aatgtatgtt aatggaatag aagtgttctc tgaaacagtt
     4681 gatacatttt tgccaatttc aaatataaat ggtatagata aggcaacact aggagctgtt
     4741 aatcgtgaag gtaaggaaca ttacctcgca aaaggaagta ttgatgaaat cagtctattt
     4801 aacaaagcaa ttagtgatca ggaagtttca aatattccct tgtcaaatcc atttcagtta
     4861 attttccaat caggagattc tactcaagct aactatttta gaataccgac actatataca
     4921 ttaagtagtg gaagagttct atcaagtatt gatgcacgtt atggtgggac tcatgattct
     4981 aaaagtaaga ttaatattgc cacttcttat agtgatgata atgggaaaac gtggagtgag
     5041 ccaatttttg ctatgaagtt taatgactat gaggagcagt tagtttactg gccacgagat
     5101 aataaattaa agaatagtca aattagtgga agtgcttcat tcatagattc atccattgtt
     5161 gaagataaaa aatctgggaa aacgatatta ctagctgatg ttatgcctgc gggtattgga
     5221 aataataatg caaataaagc cgactcaggt tttaaagaaa taaatggtca ttattattta
     5281 aaactaaaga agaatggaga taacgatttc cgttatacag ttagagaaaa tggtgtcgtt
     5341 tatgatgaaa caactaataa acctacaaat tatactataa atgataagta tgaagttttg
     5401 gagggaggaa agtctttaac agtcgaacaa tattcggttg attttgatag tggctcttta
     5461 agagaaaggc ataatggaaa acaggttcct atgaatgttt tctacaaaga ttcgttattt
     5521 aaagtgactc ctactaatta tatagcaatg acaactagtc agaatagagt agagagttgg
     5581 gaacaattta agttgttgcc tccgttctta ggagaaaaac ataatggaac ttacttgtgt
     5641 cctggacaag gtttagcatt aaaatcaagt aacagattga tttttgcaac atatactagt
     5701 ggagaactaa cctatctcat ttctgatgat agtggtcaaa catggaagaa atcctcagct
     5761 tcaattccgt ttaaaaatgc aacagcagaa gcacaaatgg ttgaactgag agatggtgtg
     5821 attagaacat tctttagaac cactacaggt aagatagctt atatgactag tagagattct
     5881 ggagaaacat ggtcggaagt ttcgtatatt gatggaattc aacaaacttc atatggcaca
     5941 caagtatctg caattaaata ctctcaatta attgatggaa aagaagcagt cattttgagt
     6001 acaccaaatt ctagaagtgg ccgtaaggga ggccaattag ttgtcggttt ggtcaataaa
     6061 gaagatgata gtattgattg gagataccac tatgatattg atttgccttc gtatggttat
     6121 gcctattctg cgattacaga attgccaaat catcacatag gtgtactgtt tgaaaaatat
     6181 gattcgtggt cgagaaatga attgcattta agcaatgtag ttcagtatat agatttggaa
     6241 attaatgatt taacaaaata aaggagaaaa acatggttaa atacggtgtt gttggagcag
     6301 ggtattttgg agctgaattg gctcgctata tgcaaaagaa tgatggagca gagattactc
     6361 ttctctatga tccagataat gcagaggcga ttgcagaaga attgggagca aaagtagcaa
     6421 gttccttaga tgagttggtt tctagcgatg aagtagattg tgttatcgtc gcaactccaa
     6481 ataatcttca taaggaaccg gttattaagg ctgcacagca tggtaaaaat gttttctgtg
     6541 aaaaaccaat tgcgctttct tatcaagatt gtcgcgagat ggtagatgcg tgtaaagaaa
     6601 acaatgtaac ctttatggca ggacatatta tgaatttctt taatggtgtt catcatgcaa
     6661 aagaactcat taatcaagga gttatcggag acgttctata ttgtcataca gctcgtaatg
     6721 gttgggaaga acaacaaccg tcagtatcat ggaaaaaaat tcgtgaaaaa tcaggtggtc
     6781 acttgtatca ccacatccat gaattggatt gcgttcaatt ccttatgggg ggcatgcctg
     6841 aaactgtaac catgacaggt ggaaatgtgg cccatgaagg tgaacatttc ggtgatgaag
     6901 atgatatgat ttttgtcaat atggaatttt ctaataagcg ttttgctttg ttagaatggg
     6961 gttcagctta tcgttggggt gaacattatg tcttaatcca aggaagcaaa ggtgccatcc
     7021 gcttagactt attcaactgt aaaggaactc ttaagctaga tgggcaagaa agctatttct
     7081 tgattcacga atcgcaagaa gaagatgatg atcggactcg tatctatcat agtacagaga
     7141 tggatggagc aattgcttat ggtaaaccag gtaaacgtac tccattatgg ctatcatctg
     7201 tcattgataa agaaatgcgc tatctgcatg agattatgga aggagctcca gtatcagaag
     7261 aatttgcaaa acttttgaca ggtgaagctg ccctagaagc aattgctact gcagatgctt
     7321 gtacccagtc tatgtttgaa gatcgcaaag taagattgtc agaaattgta aaataaattt
     7381 tggtattctc ctatctatag gtcgacttgc tcctctgaaa gtacttttag aggagctgtt
     7441 tgactttgct agtttttgaa actgaaatct attatactac aaactattga aagcgtttta
     7501 attttaaggt ataataatct catagaaata aagaaaagga ggaaagagga tgccacagat
     7561 tagcaaagaa gccttgattg agcaaatcaa agatggaatc atcgtttctt gtcaggctct
     7621 tcctcatgaa ccgctttata cagaagcggg aggggtgatt cccttgctgg tcaaagcggc
     7681 tgagcaaggt ggagcagtcg gtatccgagc aaacagtgtt cgcgatatca aggaaattaa
     7741 ggaagtcact aaacttccaa tcattgggat tatcaaacgt gattatccac ctcaggaacc
     7801 cttcatcacg gctactatga aagaagttga tgaattggca gaactggaca tcgaggtgat
     7861 tgctctggat tgtaccaagc gtgaacgcta cgatggtttg gaaattcaag agttcattcg
     7921 tcaggttaag gagaaatatc ctaatcagct tttgatggct gatactagta tcttcgaaga
     7981 agggctagca gctgtagaag caggaattga ctttgtcgga acaaccttat caggctacac
     8041 atcctacagt ccaaaagtag acggtccaga ttttgaattg attaagaaac tctgtgatgc
     8101 cggtgtagat gtcattgcag aaggaaaaat tcatacacca gaacaagcca aacaaatcct
     8161 tgaatatgga gtgcgaggca tcgttgttgg tggcgccatt actagaccaa aagagattac
     8221 agaacgcttc gttgctagtc ttaaataaga tgtgagaggg agttttatgt ttaaagtttt
     8281 acaaaaagtt ggaaaagctt ttatgttacc tatagctata cttcctgcag caggtctact
     8341 tttggggatt ggtggtgcac tttcaaaccc aaccacgata gcaacttatc caatactaga
     8401 caatagtatt tttcaatcaa tattccaagt aatgagctct gcaggagagg ttgtattcag
     8461 taatttgtca ctacttctct gtgtgggatt atgtattggc ttagcgaaac gagataaagg
     8521 aaccgctgcg ttagcaggag taactggtta cttagttatg actgcaacga tcaaagcttt
     8581 ggtaaaactt tttatggcag aaggatctgc aattgatact ggagttattg gagcattagt
     8641 tgtcggaata gttgccgtat atttgcacaa ccgatataac aatattcaat taccttccgc
     8701 tttaggattc tttggaggtt cacgcttcgt tcctattgtt acatcgttct cttctatctt
     8761 gattggcttt gtcttctttg ttatttggcc acctttccaa caacttcttg tttctacagg
     8821 tggatatatt tctcaggcgg gtccaattgg aacttttcta tatggatttt taatgagact
     8881 ttctggagca gtaggcttac atcatataat ttaccctatg ttttggtata ctgaacttgg
     8941 tggtgttgaa actattgcag gacaaacagt ggttggagct caaaaaatat tttttgctca
     9001 attagccgat ccggcccatt ctggattatt tacagaagga acaaggtttt ttgcaggtcg
     9061 tttctcaaca atgatgttcg gtttaccggc tgcctgttta gcgatgtacc atagtgttcc
     9121 taaaaatcgt cgtaaaaaat acgcgggttt gttttttgga gttgctttaa catcttttat
     9181 taccggtatt acagaaccaa ttgaatttat gtttctattc gtcagtccgg ttctatatgt
     9241 tgttcacgca ttccttgatg gtgttagctt ctttattgca gacgtcttaa atatttcaat
     9301 aggaaacaca ttttcaggag gtgtaatcga tttcacttta tttggaattt tgcaggggaa
     9361 cgctaagacg aattgggttc ttcagattcc atttggactt atttggagtg ttttgtatta
     9421 tattattttt agatggttca ttactcaatt caacgttcta acgccagggc gaggagaaga
     9481 agtagattct aaagaaattt ctgaatccgc agattcaact tcaaatactg cagattattt
     9541 aaaacaggat agcctacaaa ttatcagagc cttgggtgga tcaaataata tagaagatgt
     9601 agatgcttgt gtgacacgtt tacgtgtagc tgtaaaagaa gttaatcaag ttgataaagc
     9661 acttttaaaa caaattggtg cagttgatgt cttagaagtg aagggtggca ttcaagcaat
     9721 ctatggagca aaagcaatct tatataaaaa tagtattaat gaaattttag gtgtagatga
     9781 ttaagtactt actgacttaa taaaaaacag aggagagtga tggatgagta ggatgaaatg
     9841 aaatcgcata caagaaataa agaactcatt atccaagttg gatacgctta ttacatagga
     9901 gaatacaaat gaaatttaga aaattagctt gtacagtact tgcgggtgct gcggttcttg
     9961 gtcttgctgc ttgtggcaat tctggcggaa gtaaagatgc tgccaaatca ggtggtgacg
    10021 gtgccaaaac agaaatcact tggtgggcat tcccagtatt tacccaagaa aaaactggtg
    10081 acggtgttgg aacttatgaa aaatcaatca tcgaagcgtt tgaaaaagca aacccagata
    10141 taaaagtgaa attggaaacc atcgacttca agtcaggtcc tgaaaaaatc acaacagcca
    10201 tcgaagcagg aacagctcca gacgtactct ttgatgcacc aggacgtatc atccaatacg
    10261 gtaaaaacgg taaattggct gagttgaatg acctcttcac agatgaattt gttaaagatg
    10321 tcaacaatga aaacatcgta caagcaagta aagctggaga caaggcttat atgtatccga
    10381 ttagttctgc cccattctac atggcaatga acaagaaaat gttagaagat gctggagtag
    10441 caaaccttgt aaaagaaggt tggacaactg atgattttga aaaagtattg aaagcactta
    10501 aagacaaggg ttacacacca ggttcattgt tcagttctgg tcaaggggga gaccaaggaa
    10561 cacgtgcctt tatctctaac ctttatagcg gttctgtaac agatgaaaaa gttagcaaat
    10621 atacaactga tgatcctaaa ttcgtcaaag gtcttgaaaa agcaactagc tggattaaag
    10681 acaatttgat caataatggt tcacaatttg acggtggggc agatatccaa aactttgcca
    10741 acggtcaaac atcttacaca atcctttggg caccagctca aaatggtatc caagctaaac
    10801 ttttagaagc aagtaaggta gaagtggtag aagtaccatt cccatcagac gaaggtaagc
    10861 cagctcttga gtaccttgta aacgggtttg cagtattcaa caataaagac gacaagaaag
    10921 tcgctgcatc taagaaattc atccagttta tcgcagatga caaggagtgg ggacctaaag
    10981 acgtagttcg tacaggtgct ttcccagtcc gtacttcatt tggaaaactt tatgaagaca
    11041 aacgcatgga aacaatcagc ggctggactc aatactactc accatactac aacactattg
    11101 atggatttgc tgaaatgaga acactttggt tcccaatgtt gcaatctgta tcaaatggtg
    11161 acgaaaaacc agcagatgct ttgaaagcct tcactgaaaa agcgaacgaa acaatcaaaa
    11221 aagctatgaa acaatagtcc ttagttattc tataaaaagt agttttttaa agaacctaag
    11281 agtgtatacc cccttttccc tctacacaga tagtgtaaga aaagggggct tttgtttaaa
    11341 atgtaagaaa ctgtcacgaa attaaaatga agttcttaca taagcgaatc ataaaaaatt
    11401 tcattttgat tttaaaacag ttcaagaaag tcaaaaaatt attctatttg aaagagaggt
    11461 gccgactgtg aaagtcaata aaatccgtat gcgggaaaca gtgatttcct acgctttcct
    11521 agcaccagta ttattcttct ttgtcatctt tgtgttggct ccgatggtga tgggcttcat
    11581 tacaagtttc tttaactact caatgactaa atttgagttt gtaggcttgg ataactatat
    11641 ccgtatgttt aaagatcctg tctttacaaa atctctgatt aacacagtta ttttggttat
    11701 tggatctgta ccagttgttg ttctattctc actctttgta gcatctcaga cctatcatca
    11761 aaatgtcatt gccagatcct tctaccgttt cgtcttcttc cttcctgttg taacgggtag
    11821 tgttgccgtg acagttgttt ggaaatggat ttatgaccca ctatcaggga ttctaaactt
    11881 tgtccttaag tccagccaca tcatcagcca aaacatttct tggttgggag ataaaaactg
    11941 ggcattgatg gcgattatga ttattctctt gaccacttca gttggtcagc ccatcatcct
    12001 ttatatcgct gccatgggga atattgacaa ttcactggtt gaagcggcgc gtgttgatgg
    12061 tgcaactgag tttcaagttt tttggaagat taaatggcca agccttcttc caacaactct
    12121 ttatattgca atcatcacaa caattaactc attccagtgt ttcgccttga ttcagctttt
    12181 gacatctggt ggtccaaact actcaacaag taccttgatg tactaccttt acgaaaaagc
    12241 cttccaattg acagaatacg gctatgccaa cacaattggt gtcttcttgg cagtcatgat
    12301 tgctatcgta agctttgttc aatttaaagt acttggaaac gacgtagaat actaaagaaa
    12361 ggagacagct atgcaatcta cagaaaaaaa accattaaca gcctttactg ttatttcaac
    12421 aatcattttg ctcttgttga ctgtgctgtt catctttcca ttctactgga ttttgacagg
    12481 ggcattcaaa tcacaacctg atacaattgt tattcctcct cagtggttcc ctaaaatgcc
    12541 aaccatggaa aacttccaac aactcatggt gcagaaccct gccttgcaat ggatgtggaa
    12601 ctcagtattt atctcattgg taaccatgtt cttagtttgt gcaacctcat ctctagcagg
    12661 ttatgtattg gctaaaaaac gtttctatgg tcaacgcatt ctatttgcta tctttatcgc
    12721 tgctatggcg cttccaaaac aagttgtcct tgtaccattg gtacgtatcg tcaacttcat
    12781 gggaatccac gatactctct gggcagttat cttgcctttg attggatggc cattcggtgt
    12841 cttcctcatg aaacagttca gtgaaaatat ccctacagag ttgcttgaat cagctaaaat
    12901 cgacggttgt ggtgagattc gtaccttctg gagtgtagcc ttcccgattg tgaaaccagg
    12961 gtttgcagcc cttgcaatct ttaccttcat caatacttgg aatgactact tcatgcaatt
    13021 ggtaatgttg acttcacgta acaatttgac catctcactt ggggttgcga ccatgcaggc
    13081 tgaaatggca accaactatg gtttgattat ggcaggagct gcccttgctg ctgttccaat
    13141 cgtcacagtc ttcctagtct tccaaaaatc cttcacacag ggtattacta tgggagcggt
    13201 caaaggataa tactctgcga aaatcgaatg caaactacgt cagcttcacc ttgccatact
    13261 taagtattgc ctgcggttag cttcctagtt tgttcttcaa ttttcattga gtataggaaa
    13321 atcaatctat caagatacag aagtatattt tatagattta gagaatatag aggttataag
    13381 tgtctacaaa atggagggta tgcagttact ttatgaagtt ttgtcagacg cttatcaact
    13441 taagaatggt tttagttaac tatcagaaac gaaggaaaga gtatgatttt tgacgatttg
    13501 aaaaacatca ccttttacaa agggattcat cccaatttag acaaggctat cgactacctc
    13561 taccaacatc gtaaagattc attcgaatta ggaaagtatg agattgatgg agataaagtc
    13621 tttctagttg ttcaggaaaa tgtcctcaat caagttgaga ataatcaatt tgaacaccat
    13681 aagaactatg cagatttgca tttgctggta gaaggacatg aatattcgag ctacggttca
    13741 cgtatcaaag acgaggcagt agcattcgac gaagcgactg acattggctt tgttcattgt
    13801 catgaacact acccactctt gttgggttat cataattttg cgattttctt cccaggtgag
    13861 ccacatcagc caactggcta tgcaggtatg gaagaaaagg ttcgaaaata tctctttaaa
    13921 attttgattg attaaaaata ggatgaattg tttttttgta aagctttgac aatactctac
    13981 catgaaattg atctttgtga ggtagagaaa tgagaataaa atatttaaaa attggtatct
    14041 tctaagcatg ctgcaagagc tagtttctta gatggacagg ggattacagt tgatgagatg
    14101 tcctggataa ttaatggcat tgtgaatgca ttgattggta gatacataaa attaggtact
    14161 tatgcagcta agtatggtat tagtatagca cgctcgatct taagtagggc agctgcaact
    14221 gcagcagcaa gagtaggatt actgaccaag atttctggat ggattttacg agtagctgtg
    14281 aatgtagctg atgtatatgg taattttgcc aacaatattg ctgcagcttg ggatgcatat
    14341 gataaaattc ctaacaatgg tcgtataaac ttttaaaatg cgagaatgaa agcactttgt
    14401 atttttttat tgaatatgtt agcttggaca gtgcttgcaa tgataattcg tggagggcta
    14461 gatggatttg ataggcatac ttggagtact attttaattg cttcgctgtt cggggtatat
    14521 gattataagc ccatagataa aaatagaaaa aagtccaaaa gaaaaaagaa aaaatagatt
    14581 tgttcatggt agggacttat gaaagcttta ctgacaaaaa agaaaacagt ttacaaagaa
    14641 aaatgatgga ggagcaaaca tggcacaaaa aggagtaagc cttatcaagg cagcatttga
    14701 tacagataac tttctcatgc gttttagtga gaaggtcttg gacatcgtga cagccaatct
    14761 tctttttgtc gtctcttgtt tgcccatcgt gacgattgga gtggctaaaa tcagcctcta
    14821 cgagaccatg ttcgaagtta agaagagcag acgggtgcct gtttttaaaa tctatctaag
    14881 atctttcaag caaaatctga aactaggtct tcagttaggt ctgcttgagt tgggcattgt
    14941 ttcattaagc ctcctagatc tttatctctt ttggggtcaa acagctctgc cctttcaatt
    15001 gctgaaagct atttgtctag gcattctgat tttccttacg attgtgatgt tggctagcta
    15061 tccaatcgcg gcacgttatg atttaacttg gaaagaaatt cttcaaaaag gattgatgtt
    15121 ggctagtttt aactttcctt ggttcttcct catgttagcc attcttgtcc tcattgtgat
    15181 ggttctttat ctgtctgcct tcagtctact cttaggtggc tcagtcttcc tgctttttgg
    15241 gtttggacta ttggtcttta tccagactgg attgatggag aaaattttcg caaaatacca
    15301 ataggagcct tatttctgaa actactttca aaggctccaa acgctattct ataagcgaga
    15361 aactaaaatc taagtgtcta taagatattg aaagcctttt cggtaaagtg tatactaaag
    15421 aagtaaagaa aaatctgctt tagcagaaaa taaaaataat aggagaaaat ctatgtcaga
    15481 tttgaaaaaa tacgaaggtg tcattccagc cttctacgca tgttatgatg agcaaggaga
    15541 agtaagccca gaacgtacgc gtgccttggt tcaatacttc attgataaag gtgttcaagg
    15601 tctttatgtc aatggttctt ctggtgaatg tatctaccaa agtgttgaag accgcaagtt
    15661 aatcttggaa gaagttatgg cagttgccaa aggtaaattg accattattg cccatgttgc
    15721 ttgcaataat actaaagata gtatggaact tgctcgccat gctgaaagct tgggagtaga
    15781 tgctattgca acgattccac caatttattt ccgcttgcca gaatactcag ttgccaaata
    15841 ctggaacgat atcagttctg cagctccaaa cacagactac gtgatttaca acattcctca
    15901 attggcaggg gttgctttga ctccaagcct ttacacagaa atgttgaaaa atcctcgtgt
    15961 tatcggtgtg aagaactctt ctatgccagt tcaagatatc caaacctttg tcagccttgg
    16021 tggagaagac catatcgtct ttaatggtcc tgatgagcag ttcctaggag gacgcctcat
    16081 gggggctagg gctggtatcg gtggtactta tggtgctatg ccagaactct tcttgaaact
    16141 caatcagttg attgcggata aggacctaga cacagcgcgt gaattgcagt atgctatcaa
    16201 cgcaatcatt ggtaaactca cttctgctca tggaaatatg tacggtgtca tcaaagaagt
    16261 cttgaaaatc aatgaaggct tgaatattgg atctgttcgt tcaccattga caccagtgac
    16321 tgaagaagat cgtccagttg tagaagcggc tgctgccttg attcgtgaaa ccaaggagcg
    16381 cttcctctaa tctaaaagga ggtatttatg acatattacg ttgcaattga tatcggtgga
    16441 accaacatca agtatggttt ggttgatcaa gaggggcaac ttcttgaatc gcatgaaatg
    16501 ccaactgagg cgcataaggg tggacctcat atcttacaaa agaccaaaga tatcgtagct
    16561 agttatttag aaaaaggccc agtagcaggt gttgccatat cttctgctgg gatggtggat
    16621 ccggataagg gtgagatttt ctatgctggg ccgcaaatcc ctaactacgc aggcacccag
    16681 ttcaaaaagg aaatcgaaga aagctttact attccttgtg agattgaaaa tgatgtcaac
    16741 tgtgcaggtc ttgctgaggc agtatctggt tcaggcaagg gagcaagtgt gacactttgc
    16801 ttgaccattg gaacaggtat cggtggttgc ttgattatgg ataggaaagt cttccatggt
    16861 tttagcaatt cagcctgtga agtcgggtat atgcatatgc aggatggagc ttttcaagac
    16921 ttggcttcta caacagcttt agtgaaatat gtagctgaag cccatggaga agatgttgat
    16981 cagtggaatg gccgtagaat tttcaaagaa gccactgaag gaaacaaaat ctgcatggaa
    17041 ggtattgacc gtatggttga ctatctagga aaaggtctgg caaatatttg ctatgttgcc
    17101 aatccagaag tggttattct tggtggtggt atcatggggc aagaggctat cctcaaacct
    17161 aagatccgca cagccttgaa agaggctttg gtaccaagtt tagcagaaaa aacacgatta
    17221 gaatttgccc atcaccaaaa tacagcaggg atgttgggtg catattatca ttttaagaca
    17281 aaacaatcct agtttggctc agccaaacta ggattttctt acacgttttt gtctacgata
    17341 gccgttgagt tttttatttt cccagtagct attaaagatt ttttccttgc tttcgcgatt
    17401 gatttccaaa aagtaggcat aaatcaaatc gataaagaag agcataggaa gttgagcgga
    17461 tattcgttgg atataggagg gttggctgtg ggtggctaca agaacagtct ctgtataggt
    17521 ctggctatct ttattgggaa cacttgtaaa gagtacagtc tttgccccca tctccttggc
    17581 atctaataga ctatctaaaa tagaaggagt tgagcctgaa agtgagaagc ccagtactag
    17641 acaattttca tccatgatgc tggttgtcca ggcaaagccg tcttggtctg tcaaagcttc
    17701 gcagaccaca cctagtcgca taaaacgtaa tttcatttca cgggcgacga ggccagaact
    17761 ccctgttcca aagaagtaga tacgctcagc atcttcgatt agctgggcaa ttcgttctag
    17821 ttggatttcg tcaatcaagt cttgtgtttg ttccctcata ttgctataac ttctgaggac
    17881 tcgtttggtc agtggactgt gcttggagac ttggttggct tgattttctg cctgatgttg
    17941 gtattggaaa ataaattctc ggtagccagt aaagccacac tttttagcaa agcgggtcaa
    18001 agcagcttga gaaatatgta atttttgggt gacttgttga gaagataaat catctgtaat
    18061 cgtttcagct tgcaaaaaat agcgagcgat ttcttgttct aggtctgtca tttcttcaaa
    18121 atgtgaatca atgatagttg cgatatctgg tttgtccata gggaaagctc ctttacatga
    18181 gtcatactgg aagactagat cagggaatag tcacacttca ttataacaca taatataagg
    18241 atagataaat aaaaacgcat ctctgtttta aaaacgaaaa aatcgaaaaa gcttcttact
    18301 tttccataat tttctactca aattgtggta caattaagag taagatttta agttagaaat
    18361 gagactgatt tgtatgagaa aatttaacag ccattcgatt ccgattcggc ttaatttatt
    18421 gttttcaatc gtcattttac tctttatgac cattattggt cgtttgttgt atatgcaggt
    18481 tttgaacaag gatttttacg aaaaaaagct agcctcagct agtcagacca aggtcacaac
    18541 cagttctgct cgtggggaaa tttatgatgc tagtggaaaa cctttggtag aaaatacgtt
    18601 aaaacaggtt gtttccttta cgcgtagcaa taaaatgacg gctacagact taaaagaaac
    18661 agctaaaaag ttactgactt atgtgagcat cagttcgcca aatttgacag aacgccagct
    18721 ggctgattac tatttggctg atcctgaaat ctataaaaaa acagtggaag ctctcccaag
    18781 tgagaaacgc ttggattcag atggtaatcg cctatccgaa tcagaactgt ataacaatgc
    18841 ggtcgatagt gtcccaacaa gtcaactaaa ctatacagag gatgaaaaga aagaaatcta
    18901 tctttttagt cagttaaatg ctgttggaaa ctttgcgaca ggaaccattg cgacagatcc
    18961 tctaaatgat tctcaggtgg ctgttattgc ctctatttca aaggagatgc ctggcattag
    19021 tatttctact tcttgggatc gaaaggtttt ggaaacttcc ctttcttcta tagtagggag
    19081 tgtatccagt gaaaaagctg gtctcccagc ggaagaagca gaagcctatc ttaaaaaagg
    19141 ctattctcta aatgaccgtg ttggaacctc ctatttggaa aagcaatatg aagagacctt
    19201 acaagggaaa cgctcggtaa aagaaatcca tctggataaa tatggcaata tggaaagtgt
    19261 ggatacaatt gaggaaggta gtaagggaaa caatatcaaa ctgaccattg atttggcctt
    19321 ccaagatagc gtggatgctt tgctgaaaag ttatttcaat tcagagttgg gaaatggtgg
    19381 agccaagtat tctgaaggtg tctatgcagt cgcccttaac ccaaaaacag gtgctgtttt
    19441 gtctatgtca gggattaaac atgacttgaa aacgggagag ttgacgccgg attccttggg
    19501 aacggtaacc aatgtctttg ttccaggttc ggttgtcaag gcggcgacca tcagctcagg
    19561 ctgggaaaat ggagtcttgt caggaaatca gaccttgaca gaccagtcca ttgtcttcca
    19621 aggttcagct ccaattaatt cttggtatac tgccttttct aggccaatgc cgattacggc
    19681 agttcaggct ctagagtatt catccaatgc ttatatggtc caaacagcct taggtcttat
    19741 ggggcaaacc tatcaaccaa atatgtttgt cggcaccagc aatctagagt ctgctatggg
    19801 taaattgcgt tcaacctttg gcgaatatgg cttgggttct gcgacaggaa ttgacctacc
    19861 agatgaatct actggattta ttcccaaaga gtatagcttt gctaattaca ttactaatgc
    19921 ctttgggcag tttgataact ataccccaat gcaattggct cagtatgtgg caactattgc
    19981 aaatgatggt gttcgtgtgg ctcctcgtat tgttgaaggc atttatggta ataatgataa
    20041 gggaggactg ggcgacttga ttcagcaact gcaaccgaca gagatgaata aggtcaatat
    20101 atccgactcc gatatgagtg tcttgcacca aggtttttat caggttgctc atgggactag
    20161 cggattgaca actggacgtg ccttttcaaa tggtgccttg gtatccatta gcggaaaaac
    20221 gggtacagcc gaaagctatg tggcagatgg tcagcaagca accaatacca atgcggtggc
    20281 ctatgcccca tctgataatc cccaaatcgc tgttgcagtg gtctttcctc ataataccaa
    20341 tctaacaaat ggtgtagggc cttccattgc gcgtgacatt atcaatctgt atcaaaaata
    20401 ccatccgatg aactagaaag gaaattatgc tttatccaac acctattgcc aagttgattg
    20461 acagttattc taagttacca ggtatcggga ttaagacggc tacgcgtctg gccttttata
    20521 cgattgggat gtctgctgat gatgtcaatg aatttgcaaa aaatctcctt tctgctaaga
    20581 gagaattgac atattgttct atttgtggac gtttgacaga cgacgatcct tgttctatct
    20641 gtactgatcc gactcgtgac cagacaacaa ttttagttct tgaggatagt agagatgtgg
    20701 cagccatgga aaatatccaa gaataccatg gactctatca tgtcctgcat ggcctcattt
    20761 ctcctatgaa tggtatcagt ccggacgata tcaatctcaa gagccttatg actcgtctta
    20821 tggatagtga ggtttcagaa gtgattgtgg cgactaatgc tacagcggat ggtgaagcga
    20881 cttccatgta tctttcacgt ttgctcaagc cggttggtat caaggttacg cgtctagcac
    20941 gaggtctcgc tgtgggagcg gacattgagt atgcggacga agtgacactc ttacgagcga
    21001 ttgaaaatcg gacagagttg taagtgtagg caaatttacg aactcccttc atttataaaa
    21061 aatcaaagag gctgaaaatc gttcctatcg gcctcttttt gtatagtgtg atgagtagga
    21121 tcgggttcaa gttttaaaaa accaagcaaa tatgatatac taaagagcga gtattctagt
    21181 agaattagga caaataatat gaaacaaacg attattcttt tatatggtgg acggagtgcg
    21241 gaacgcgaag tctctgtcct ttcagctgag agtgtcatgc gtgcggtcaa ttacgaccgt
    21301 ttcacagtca agactttctt tatcagtcag tcaggtgact ttatcaaaac acaggaattt
    21361 agtcatgctc cggggcaaga agaccgtctc atgaccaatg aaaccattga ttgggataag
    21421 aaagttgcac caagtgctat ctacgaagaa ggtgcagtgg tctttccagt ccttcacggg
    21481 ccaatgggag aagatggctc tgttcaagga ttcttggaag ttttgaaaat gccttacgtt
    21541 ggttgcaaca ttttgtcatc aagtcttgcc atggataaaa tcacgactaa gcgtgttctg
    21601 gaatctgctg gtattgccca agttccttat gtggctatcg ttgaaggcga tgatgtgact
    21661 gctaaaatcg ctgaagtgga agaaaaattg gcttatccag tcttcactaa gccgtcaaac
    21721 atggggtcta gtgtcggtat ttctaagtct gaaaaccaag aagaactccg tcaagcctta
    21781 aaacttgcct tccgatatga cagccgtgtc ttggttgagc aaggagtgaa tgcccgtgaa
    21841 attgaggttg gcctcttggg taactacgat gtcaagagca cgctacctgg agaagttgtc
    21901 aaggacgttg ccttttatga ctacgatgcc aagtatattg ataacaagat tactatggat
    21961 attcctgcca aaatcagtga tgatgtggtg gctgtcatgc gtcaaaatgc agaaacagcc
    22021 ttccgtgcca ttggtggcct tggtctatct cgttgcgatt tcttctatac agataaggga
    22081 gagatttttc tcaacgagct caataccatg ccaggtttca cccagtggtc tatgtaccca
    22141 ctactttggg acaatatggg gatcagctac ccagaactaa tcgagcgttt ggttgacctt
    22201 gccaaggaaa gttttgacaa gcgcgaagcg catttgatat aaaatgaaag agagggtaga
    22261 agccagaacc atcactgcaa ggtgactaga gttctcggac ttcagccctt tttaaaggag
    22321 tagaaatgaa attaacaatc catgaaattg cccaagttgt tggagccaaa aatgatatca
    22381 gtatctttga ggacacccag ttagaaaaag ctgagtttga tagtcgtttg attggaactg
    22441 gagatttatt tgtgccactt aaaggtgcgc gtgacggtca tgactttatc gaaagagctt
    22501 ttgaaaatgg tgcggcagca accctgtctg agaaagaggt tgcaaatcat ccctacattc
    22561 tagtagatga tgttttgact gcctttcaac aactagctgc ctactatctt gaaaaaacag
    22621 ctgttgatgt ctttgcggtt acgggttcaa atggcaagac aacgactaag gatatgttgg
    22681 cgcatttact gtcaacgacc tacaagacct acaaaacaca aggcaactac aataacgaga
    22741 ttggccttcc ctacacagtt ctacacatgc ctgaaggaac agaaaagttg gttttggaga
    22801 tggggcagga ccacttgggc gatattcatc tcttgtctga attggctcgt ccaaaaacag
    22861 ccatcgtgac cttggttgga gaagctcatt tagccttttt caaagatcgt tctgagattg
    22921 ctaaaggaaa aatgcaaatt gcagacggaa tggcttcagg ttccttgctt ttagcgccgg
    22981 ctgaccctat cgtagaggac tatttgccaa ctgataaaaa ggtggttcgt tttgggcaag
    23041 gggtagagct ggaaattact gacttggttg agcgcaaaga tagtctgacc ttcaaggcca
    23101 atttcttaga gcaagtcctt gatttgccag taactggcaa gtacaatgcg acaaatgcta
    23161 tgattgcatc ctatgttgcc ttgcaagaag gagtttcaga ggagcaaatt cgtttggcct
    23221 tccaagatct tgaattgacg cgtaaccgta ccgagtggaa gaaagcagcc aatggagcag
    23281 atatcctgtc agatgtttac aatgccaatc caactgctat gaaactgatt ttagagactt
    23341 tctctgccat tccagccaat gaaggtggca agaaaattgc agttttggcg gatatgaagg
    23401 agcttggtga ccagtctgtt caacttcata atcagatgat tttgagcctc tccccagatg
    23461 tgcttgatat cgttattttc tatggagaag acattgctga attagcccaa ttggccagtc
    23521 aaatgttccc aattggccac gtttactact tcaagaaaac agaagaccaa gaccaatttg
    23581 aagacttagt caagcaggtc aaggaaagcc tcagtgccaa tgatcaaatc ttgctcaagg
    23641 gctctaactc tatgaaccta gccatgttgg tagaaagttt agaaaatgaa accaagtgat
    23701 tttgttaagt atctgtaaag aatgattgcc cttacagata ctggcttaac ctttacaaaa
    23761 gagccttttg accgtgagcg ctacgaagac ttgcgaagtc tgttatctga aatgttgaat
    23821 caggtatcag accttgatgc agacgaagtg gcagaactct tgaaaccgac ctccgcttat
    23881 gcgactccct taatggacgt ccgtgcttgg attgttgagg atgagaagat ttgtctggtt
    23941 aggggacaag gagaggatag ttgggctttg ccaggtggct ttggtgaagt cggctattct
    24001 ccaactgaaa atattctcaa ggaaattgaa gaagaaaccg gttttaaagc caaagttgaa
    24061 agactgctag ctgtttttga taccaatcgt ttccaactac agagcaaaca atatgcaaag
    24121 tttgtttttg aatgtaagct tctcgatgga caattccaag aaaatcaaga aatcgctgac
    24181 cttcaatttt ttgcaattga ccaactgccg aatttatctg aaaaacgcat taccaaggag
    24241 caaatcgaga ttctttggca ggtttatcaa ggtcagaggg agcaatatct tgactaagaa
    24301 gatgattatc gtatttctaa attcattttt cttaagtagc atggtataat aaaatgcagg
    24361 aaaattttga atcatgagga agactagatg aatttatggg atattttctt tacgactcag
    24421 gcaaccgagc cgcccaaatt tgaccttttt tggtatgtta gcctatttac gctcttagcc
    24481 ttaacctttt atacagccca tcgctatcgt gaaaagaagg tttaccaacg atttttccaa
    24541 atcttgcaga ctgttcagtt aatccttctt tatggttggt actgggtcaa tcatatgcca
    24601 ctgtcagaaa gcctaccctt ttaccattgc cgtatggcta tgtttgtggt actcttgctt
    24661 cctggtcagt ccaaatataa acaatacttt gcattattgg gaacatttgg gacattagca
    24721 gcctttgttt atccagtgcc agatgcttac ccttttccac atatcaccat tctatccttt
    24781 atctttggtc atttagcact cttggggaac tctctagttt atctattgag acagtataat
    24841 gcgcgattgc tggatgtgaa gggaattttt ctcatgacct ttgccctaaa tgccttgatt
    24901 tttgtggtca atttggtgac aggtggcgat tacggatttt tgacaaaacc gccattggtt
    24961 ggggatcacg gtctagtagc taattattta cttgtttcaa ttgtgctggt agctactatc
    25021 agtttgacta agaaaatctt agaattcttt ttagctcaag aagcagaaaa aatgattgca
    25081 aaggaagctt aacacagagc tttctttttt gctcttagag agtttttaca agcagcttat
    25141 aaaataagaa tttctgaata gacaaactca aaaaatggct gggaaattta ggaaaaaagc
    25201 aagcacgatt aaattttttg tgttataata ttttgtgaat agctatgcct atgtttagct
    25261 atggaataat acgaagtgcg aaacttggaa gatagagagg aagcgatgta atggctagag
    25321 aaggcttttt tacaggtcta gatattggaa caagctctgt caaggtgctt gtggccgagc
    25381 agagaaatgg tgaattaaat gtaattggcg tgagtaatgc caaaagtaaa ggtgtaaagg
    25441 atggaattat tgttgatatt gatgcagcag caactgctat caagtcagcc atttcccaag
    25501 cggaagaaaa ggcaggcatt tcgattaaat cagtaaatgt cggcttgcct ggtaatcttt
    25561 tgcaggtaga accaactcag gggatgattc cagtaacatc tgatactaag gaaattacgg
    25621 atcaagatgt tgaaaatgtt gtcaaatcag ctttgacaaa gagtatgaca cctgaccgtg
    25681 aagtcattac ctttattcct gaagaattta ttgtggatgg tttccaaggg attcgtgacc
    25741 cacgtggcat gatgggggtt cgccttgaaa tgcgtggttt gctttataca ggacctcgta
    25801 ctatcttgca caatttgcgt aagacggttg agcgtgcagg tgttcaggtt gaaaatgtta
    25861 tcatttcacc actagcaatg gttcagtctg ttttgaacga aggggaacgt gaatttggtg
    25921 ctacagtgat tgatatgggg gcaggtcaaa cgactgtcgc tacaatccgt aatcaagaac
    25981 tccagttcac acatattctc caagaaggtg gagattatgt aactaaagat atctccaagg
    26041 ttttgaaaac ctctcgcaaa ttagcggaag gcttgaaact gaattacggg gaagcctatc
    26101 cgcctcttgc aagcaaagaa accttccaag tagaggttat tggagaagta gaagcagtcg
    26161 aagtgacgga agcctacttg tcagaaatta tttctgcacg aatcaagcac atccttgaac
    26221 aaatcaagca agaattagat agaaggcgtc tattggacct ccctggtggt attgtcttaa
    26281 tcggtgggaa tgccatttta ccaggtatgg ttgagcttgc tcaggaagtc tttggcgtcc
    26341 gtgtcaagct ttatgttcca aatcaagttg gtatccgtaa tccagccttt gcgcatgtga
    26401 ttagtttatc agaatttgcg ggtcaattaa cagaagttaa tcttttggct cagggagcga
    26461 taaaaggtga gaatgactta agtcatcagc caattagttt tggtgggatg ctgcaaaaaa
    26521 cagctcagtt tgtacaatca acgcctgttc aaccagctcc tgctccagaa gtagagccgg
    26581 tggcgcctac agaaccaatg gcggatttcc aacaagcttc acaaaataaa ccgaaattag
    26641 cagatcgttt ccgtggattg atcggaagca tgtttgacga ataaagagga aaaataaatt
    26701 atgacatttt catttgatac agctgctgct caaggggcag tgattaaagt aattggtgtc
    26761 ggtggaggtg gtggcaatgc catcaaccgt atggtcgacg aaggtgttac aggcgtagaa
    26821 tttatcgcag caaacacaga tgtacaagca ttgagtagta caaaagctga gactgttatt
    26881 cagttgggac ctaaattgac tcgtggtttg ggtgcaggag gtcaacctga ggttggtcgt
    26941 aaagccgctg aagaaagcga agaaacactg acggaagcta ttagtggtgc cgatatggtc
    27001 ttcatcactg ctggtatggg aggaggctct ggaactggag ctgctcctgt tattgctcgt
    27061 atcgccaaag atttaggtgc gcttacagtt ggtgttgtaa cacgtccctt tggttttgaa
    27121 ggaagtaagc gtggacaatt tgctgtagaa ggaatcaatc aacttcgtga gcatgtagac
    27181 actctattga ttatctcaaa caacaatttg cttgaaattg ttgataagaa aacaccgctt
    27241 ttggaggctc ttagcgaagc ggataacgtt cttcgtcaag gtgttcaagg gattaccgat
    27301 ttgattacca atccaggatt gattaacctt gactttgccg atgtgaaaac ggtaatggca
    27361 aacaaaggga atgctcttat gggtattggt atcggtagtg gagaagaacg tgtggtagaa
    27421 gcggcacgta aggcaatcta ttcaccactt cttgaaacaa ctattgacgg tgctgaggat
    27481 gttatcgtca acgttactgg tggtcttgac ttaaccttga ttgaggcaga agaggcttca
    27541 caaattgtga accaggcagc aggtcaagga gtgaacatct ggctcggtac ttcaattgat
    27601 gaaagtatgc gtgatgaaat tcgtgtaaca gttgtcgcaa cgggtgttcg tcaagaccgc
    27661 gtagaaaagg ttgtggctcc acaagctaga tctgctacta actaccgtga gacagtgaaa
    27721 ccagctcatt cacatggctt tgatcgtcat tttgatatgg cagaaacagt tgaattgcca
    27781 aaacaaaatc cacgtcgttt ggaaccaact caggcatctg cttttggtga ttgggatctt
    27841 cgccgtgaat cgattgttcg tacaacagat tcagtcgttt ctccagtcga gcgctttgaa
    27901 gccccaattt cacaagatga agatgaattg gatacacctc catttttcaa aaatcgttaa
    27961 gtaaatgaat gtaaaagaaa atacagaact tgtttttcga gaagttgcag aggctagtct
    28021 gagtgctcat cgagagagtg gttcggtctc tgtcattgca gttaccaagt atgtagatgt
    28081 accgacagcg gaagccttgc ttccgctagg tgttcatcat atcggtgaaa atcgtgtaga
    28141 taagtttctg gaaaaatatg aagctttaaa agatcgagat gtgacttggc atttgattgg
    28201 taccttgcaa agacgtaagg tgaaagatgt cattcaatac gttgattatt tccatgcatt
    28261 ggactcagta aagctagcag gggaaattca aaaaagaagt gaccgagtca tcaaatgttt
    28321 ccttcaagta aatatttcta aagaagaaag caaacacggt ttttcgagag aggaactgct
    28381 ggaaatcttg ccagagttag ccagactaga taagattgaa tatgttggtt taatgacgat
    28441 ggcacctttt gaggctagca gtgagcagtt gaaagagatt ttcaaggcgg cccaagattt
    28501 acaaagagaa attcaagaga aacaaattcc aaatatgcct atgaccgagt taagtatggg
    28561 aatgagtcgt gattataaag aagcgattca attcggttcc acttttgttc gtataggtac
    28621 atcatttttt aagtaggaga gaaccatgtc tttaaaagat agattcgata gatttataga
    28681 ttattttacg gaggatgagg attcaagtct cccttatgaa aaaagagatg agcctgtgtt
    28741 tactccagta aattcttcac aggaaccggc tctcccaatg aatcaacctt cacagtcggc
    28801 tggtacaaaa gagaacaata tcaccagact tcatgcaaga caacaggaat tggcaaatca
    28861 gagtcagcgt gcaacggata aggtcattat agatgttcgt tatcctagaa aatatgagga
    28921 tgcaacagaa attgttgatt tattggcagg aaacgaaagt atcttgattg attttcagta
    28981 tatgacagag gtgcaggctc gtcgttgttt ggactatttg gatggagctt gtcatgtttt
    29041 agctggaaat ttgaaaaagg tagcttctac catgtatttg ttgacaccag ttaatgttat
    29101 tgtaaatgtt gaagatatcc gtttaccaga tgaagatcaa cagggtgagt tcggttttga
    29161 tatgaagcga aatagagtac gataatgatt tttttaattc gtatgattta taatgcagtg
    29221 gatatttact ccctgatttt ggtagccttc gctgtcatgt cttggtttcc aggtgcctac
    29281 gaatccagtt taggtcgttg gattgtagcg ttggtgaaac cagtacttgc tcccttgcaa
    29341 cgcctgcctt tacagatagc gggtcttgat ttatctgttt gggtcgcgat tgttttggtt
    29401 cgatttttag gagaaaacct agtgcgtttt ctggcgatga taggatgaat aaagggattt
    29461 atcagcattt ctccatagaa gatcgtccat ttcttgacaa gggaatggaa tggataaaga
    29521 aggtagaaga tagctatgct ccttttttaa ctccttttat caatcctcat caggagaagc
    29581 tattaaagat tttggccaaa acctatggtc ttgcttgtag cagtagtggg gaattcgtct
    29641 cgagtgagta tgttcgagtt ttattatacc cagattattt ccaaccagag ttttcagatt
    29701 ttgaaatatc tctccaagaa attgtgtatt ccaataaatt tgaacattta acgcatgcta
    29761 agattttagg gacagtcatc aatcaattag ggattgaacg gaaacttttt ggagatatcc
    29821 tagtagatga agaacgggcg cagattatga ttaatcagca gtttcttctt ctctttcaag
    29881 atggactaaa gaaaattggt cgtatacctg tttcgctgga ggaacgtcct ttcaccgaga
    29941 aaatagataa gctagaacag tatcgagaac tggatttatc tgtgtctagt tttcgattag
    30001 atgttctttt atcaaatgtt ttgaaactat ctaggaatca agcaaaccag ttgattgaaa
    30061 agaaacttgt ccaagtaaat tatcatgtgg tagacaaatc agattacact gttcaagttg
    30121 gagacttgat tagtgtgaga aaatttggtc gcttgagatt acttcaagat aagggacaaa
    30181 cgaaaaaaga gaagaaaaaa ataaccgtcc agttattatt aagtaagtga ggaatagaat
    30241 gccaattaca tcattagaaa taaaggacaa gacttttgga actcgattca gaggttttga
    30301 tccagaagaa gtcgatgaat ttttagatat tgtggttcgt gattacgaag atcttgtgcg
    30361 tgcgaatcat gataaaaatt tgcgtattaa gagtttagaa gagcgtttgt cttactttga
    30421 tgaaataaaa gattcattga gccagtctgt attgattgct caggatacag ctgagagagt
    30481 gaaacaggcg gcgcatgaac gttcaaacaa tatcattcat caagcagagc aagatgcgca
    30541 acgcttgttg gaagaagcta aatataaggc aaacgagatt cttcgtcaag caactgataa
    30601 tgctaagaaa gtcgctgttg aaacagaaga attgaagaac aagagccgtg tcttccacca
    30661 acgtctcaaa tctacaattg agagtcagtt ggctattgtt gaatcttcag attgggaaga
    30721 tattctccgt ccaacagcta cttatcttca aactagtgat gaagccttta aagaagtggt
    30781 tagcgaagta cttggagaac cgattccagc tccaattgaa gaagaaccaa ttgatatgac
    30841 acgtcagttc tctcaagcag aaatggaaga attacaagct cgtattgagg tagccgataa
    30901 agaattgtct gaatttgaag ctcagattaa acaggaagtg gaaactccaa ctcctgtagt
    30961 gagtcctcaa gttgaagaag agcctctgct catccagttg gcccaatgta tgaagaacca
    31021 gaagtagctc cagtgcatcc gacaggtcca acaccagcta cagaaactgt tgattcagca
    31081 ccaggatttg aagcaccgca agaatccgtt acaattttat aagaaacgat gtgagaacaa
    31141 tatcttatcc ttatatttcc agcgagcagg agatggtgtg agtcctgcat tccctaacga
    31201 taagattatc ctctcaaaaa ctcaagtctg aagctagtaa gatttgacgt ttcccacgtt
    31261 acgggataag agggagaaag actaaatctt tttccgaata aaggtggtac cacgattttc
    31321 gtcctttttg gaagtcgtgg tttttaattt gttattattt ataaaggaga taccatgaaa
    31381 ctcaaagata cccttaatct tgggaaaaca gctttcccaa tgcgtgcagg ccttccgacc
    31441 aaagagccag tttggcaaaa ggaatgggaa gatgcaaaac tttaccaacg tcgtcaagaa
    31501 ctaaatgaag ggaaaccgca ttttgtcttg catgatggcc ctccatacgc aaacggaaat
    31561 atccacgttg gacatgccat gaatcatatc tcaaaagata tcatcattcg ttctaagtct
    31621 atgtcaggtt ttaacgcacc ttatatccca ggttgggata ctcatggtct gccaatcgag
    31681 caagttttgg caaagcaagg tgtgaagcgc aaagaaatgg acttggttga gtacttgaaa
    31741 ctctgtcgtg agtacgctct ttctcaagtt tataaacaac gtgatgattt caaacgcttg
    31801 gggatgtcag gtgactggga aaatttatat gtgactttaa ctccagacta tgaagcagcc
    31861 caaatccgtg tctttggtga gatggctaat aagggttata tctaccgtgg tgccaagcca
    31921 gtttactggt catggtcatc tgagtcagcc cttgccgaag cggaaattga ataccatgat
    31981 ttggtttcga cttcacttta ttatgccaat aaggtaaaag atggcaaagg tatcctagat
    32041 acagatactt atatcgtagt ctggacaaca actccattta ccatcacagc ttctcgtggt
    32101 ttgactgttg gtgcagatat tgattacgtt ttggttcaac ctgctagtga aactcgtaag
    32161 tttgtcgttg ctgcagaatt gttgactagc ttgtctgaga aatttggctg ggctgatgtt
    32221 caagtgttgg caacttaccg tggtcaagaa ctcaaccaca tcgtaacaga acacccatgg
    32281 gatacagctg tagatgagtt ggtaatcctt ggtgatcacg ttaccactga ctctggtaca
    32341 ggtatcgtcc atacagcccc tggttttggt gaggacgact acaatgttgg tattgctaat
    32401 ggtcttgaag tcgcagtgac tgttgacgaa cgcggtatca tgatggcgaa tgctggtcct
    32461 gagtttgaag gtcagttcta cgacaaggtt gtaccaactg ttattgaaaa acttggtaac
    32521 ctccttctag cccaagaaga aatctctcac tcatacccat ttgactggcg tactaagaaa
    32581 ccaatcatct ggcgtgcagt tccacaatgg tttgcctcag tttcaaaatt ccgccaagaa
    32641 atcttggatg ctattgataa agttaaattc catacagaat ggggtaaagt acgtctatat
    32701 aatatgattc gtgaccgtgg tgactgggtt atctctcgtc aacgtgcttg gggtgttcca
    32761 cttccaatct tctatgcaga agacggtaca gctatcatga cagctgagac tattgaacat
    32821 gtggcgcaac tctttgaagt acatggttca agcatttggt gggaacgtga tgccaaagac
    32881 ctcttaccag aaggatttac acatccaggt tctccaaatg gggagttcaa gaaagaaaca
    32941 gatattatgg atgtatggtt tgactcaggt tcatcatgga atggtgtttt ggtaaatcgt
    33001 ccaaatctga cttatccagc tgacctttac cttgaaggtt ctgaccaata ccgtggttgg
    33061 ttcaactcat cactcattac atctgttgcc aaccatggcg tagcacctta caaacaaatc
    33121 ttgtcacaag gttttaccct tgatggtaaa ggtgagaaga tgtctaaatc acttggaaat
    33181 accattgctc caagtgatgt tgaaaaacaa tttggtgcag aaatcttgcg tctctgggta
    33241 acaagtgttg actcaagcaa tgacgtgcgt atctctatgg atattttgag ccaagtttct
    33301 gaaacttacc gtaagattcg taacactctt cgtttcttga ttgccaatac atctgacttt
    33361 aacccagctc aagatgtagt cgcttacgat gaacttcgtt cagttgataa gtacatgact
    33421 attcgcttta accagcttgt caagaccatt cgtgatgcct atgcggactt tgaattcttg
    33481 acaatctaca aggccttggt gaactttatc aacgttgact tgtcagcctt ctaccttgat
    33541 tttgccaaag atgttgttta cattgaaggt gccaaatcat tggaacgccg tcaaatgcag
    33601 actgttttct atgacattct tgtcaaaatc accaaactct tgacaccaat ccttcctcac
    33661 actgcggaag aaatctggtc atatcttgag tttgaagctg aagacttcgt tcaattgtca
    33721 gaattgccag aagctcaaac ttttgctaat caagaagaag tcttggatac atgggcagcc
    33781 ttcatggact tccgtggaca agctcaaaaa gccttggaag aagctcgtaa tgcaaaagtc
    33841 atcgggaaat cgcttgaagc acacttgaca gtttatccaa atgaagttgt gaaaactcta
    33901 ctcgaagcag taaacagcaa tgtggctcaa cttttgatcg tgtcagactt gaccatcgca
    33961 gaagggccag ctccagaagc tgcccttagc ttcgaagatg tagccttcac agttgaacgc
    34021 gctgcaggtc aagtatgtga ccgttgccgt cgtatcgacc caacaacagc agaacgcagc
    34081 taccaggcag tcatctgtga ccactgtgca agcatcgtag aagaaaactt tgcggaagca
    34141 gtcgcagaag gatttgaaga gaaataaggt tgaaaagtct aggcaaaatt caatttgaga
    34201 agaaaagaca actaatttta tagtctatta aacgcattgt atcacgtttt tgaatacctg
    34261 atatgatgcg ttttttattt attttaaaaa tttgcgaggt atgacttttt atactcaaca
    34321 agaatcaaag agaaacttag caagctaaca gtagtaagat aaaataggaa tttgatatta
    34381 gggataagat tgctaaatag tgtaatattt ttacaata
//
LOCUS       DAVLTG010000019        32796 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLTG010000019 DAVLTG010000000
VERSION     DAVLTG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.019"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(546..1235)
                     /gene="rplA"
                     /locus_tag="VYN12_000961"
     CDS             complement(546..1235)
                     /gene="rplA"
                     /locus_tag="VYN12_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1415371.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1443..1868)
                     /gene="rplK"
                     /locus_tag="VYN12_000962"
     CDS             complement(1443..1868)
                     /gene="rplK"
                     /locus_tag="VYN12_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1415372.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1991..2707)
                     /locus_tag="VYN12_000963"
     CDS             complement(1991..2707)
                     /locus_tag="VYN12_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1415373.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2725..3186)
                     /locus_tag="VYN12_000964"
     CDS             complement(2725..3186)
                     /locus_tag="VYN12_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1415374.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3188..4225)
                     /locus_tag="VYN12_000965"
     CDS             complement(3188..4225)
                     /locus_tag="VYN12_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1415375.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4323..5648)
                     /gene="brnQ"
                     /locus_tag="VYN12_000966"
     CDS             complement(4323..5648)
                     /gene="brnQ"
                     /locus_tag="VYN12_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1415376.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5819..5911)
                     /locus_tag="VYN12_000967"
     CDS             complement(5819..5911)
                     /locus_tag="VYN12_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1415377.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5954..6106)
                     /locus_tag="VYN12_000968"
     CDS             complement(5954..6106)
                     /locus_tag="VYN12_000968"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1415378.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(6266..6844)
                     /locus_tag="VYN12_000969"
     CDS             complement(6266..6844)
                     /locus_tag="VYN12_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1415379.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6898..8298)
                     /gene="pepV"
                     /locus_tag="VYN12_000970"
     CDS             complement(6898..8298)
                     /gene="pepV"
                     /locus_tag="VYN12_000970"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1415380.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8311..8916)
                     /locus_tag="VYN12_000971"
     CDS             complement(8311..8916)
                     /locus_tag="VYN12_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1415381.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9087..9887
                     /locus_tag="VYN12_000972"
     CDS             9087..9887
                     /locus_tag="VYN12_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1415382.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10071..10904)
                     /locus_tag="VYN12_000973"
                     /pseudo
     CDS             complement(10071..10904)
                     /locus_tag="VYN12_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10894..12741)
                     /gene="uvrC"
                     /locus_tag="VYN12_000974"
     CDS             complement(10894..12741)
                     /gene="uvrC"
                     /locus_tag="VYN12_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1415383.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGSLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12781..13482)
                     /locus_tag="VYN12_000975"
     CDS             complement(12781..13482)
                     /locus_tag="VYN12_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1415384.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDHWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13561..14793)
                     /gene="murN"
                     /locus_tag="VYN12_000976"
     CDS             complement(13561..14793)
                     /gene="murN"
                     /locus_tag="VYN12_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1415385.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14798..16018)
                     /gene="murM"
                     /locus_tag="VYN12_000977"
     CDS             complement(14798..16018)
                     /gene="murM"
                     /locus_tag="VYN12_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1415386.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16130..16909)
                     /locus_tag="VYN12_000978"
     CDS             complement(16130..16909)
                     /locus_tag="VYN12_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1415387.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNFAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16978..18639)
                     /locus_tag="VYN12_000979"
     CDS             complement(16978..18639)
                     /locus_tag="VYN12_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1415388.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18814..21036)
                     /gene="recJ"
                     /locus_tag="VYN12_000980"
     CDS             complement(18814..21036)
                     /gene="recJ"
                     /locus_tag="VYN12_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1415389.1"
                     /translation="MITPTYEWQFALQVENADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEVSFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMMDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21313..22072
                     /locus_tag="VYN12_000981"
                     /pseudo
     CDS             21313..22072
                     /locus_tag="VYN12_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22112..22876
                     /locus_tag="VYN12_000982"
     CDS             22112..22876
                     /locus_tag="VYN12_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1415390.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22889..23566
                     /locus_tag="VYN12_000983"
     CDS             22889..23566
                     /locus_tag="VYN12_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415391.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPFYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23576..24235
                     /locus_tag="VYN12_000984"
     CDS             23576..24235
                     /locus_tag="VYN12_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415392.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEVGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLVKRWQQAA
                     E"
     gene            24530..25720
                     /locus_tag="VYN12_000985"
     CDS             24530..25720
                     /locus_tag="VYN12_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1415393.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKIIHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26041..26922)
                     /locus_tag="VYN12_000986"
     CDS             complement(26041..26922)
                     /locus_tag="VYN12_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1415394.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLTDGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27063..28391)
                     /gene="vncS"
                     /locus_tag="VYN12_000987"
     CDS             complement(27063..28391)
                     /gene="vncS"
                     /locus_tag="VYN12_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1415395.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(28388..29044)
                     /gene="vncR"
                     /locus_tag="VYN12_000988"
     CDS             complement(28388..29044)
                     /gene="vncR"
                     /locus_tag="VYN12_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1415396.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29093..29176)
                     /gene="pep27"
                     /locus_tag="VYN12_000989"
     CDS             complement(29093..29176)
                     /gene="pep27"
                     /locus_tag="VYN12_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1415397.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29356..30735)
                     /gene="vex3"
                     /locus_tag="VYN12_000990"
     CDS             complement(29356..30735)
                     /gene="vex3"
                     /locus_tag="VYN12_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1415398.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30787..31434)
                     /gene="vex2"
                     /locus_tag="VYN12_000991"
     CDS             complement(30787..31434)
                     /gene="vex2"
                     /locus_tag="VYN12_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1415399.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31447..32724)
                     /locus_tag="VYN12_000992"
     CDS             complement(31447..32724)
                     /locus_tag="VYN12_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415400.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9268 a         7509 c         6101 g         9918 t
ORIGIN      
        1 cgagtagggg ataatctcta gcccctctca caccaccgta cgtgccgttc ggcatacggc
       61 ggttcaacta acttttaacg catgtcgttc aaggtaataa tccaaacacg aaaccagtcc
      121 acgtttttca aggactggtt ttgatatagc acgtttaagt accgacttct gagctactat
      181 agtagattga aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg
      241 actgtcctga acgattcgtc ctattcttat ttcattttat tataattgat agtggtcgcc
      301 ccagccagat accttatccg ctatataggc cttactatca cgttcctgtt cgtagagcca
      361 cgatttcgct atcccttcct ctgacgattc ttatttccag cgtcagactt gggaatcgct
      421 attgggttca ccggtagtag gtgcccaccg aggacttaca cctcagatat acgacatgcc
      481 cgtcgtacat caaaaaaagt tgagacatag tgtcttcaac ttttttacat tactttaact
      541 actgattaaa gtgagtttac gtcaactttg ataccaacac cttgagtagt tgtgatagtc
      601 aagtttgtta cgtaagttcc tttagctgta gctggtttta ctttttggat tgtttcgttg
      661 aaagctttaa agttttcaac caatttttca gcttcaaatg atactttacc gatgattgct
      721 tgaacgttac ctgcacggtc agcacggtaa gtgattttac cacctttaga ctcttcaact
      781 gctttagcaa catccattgt tacagtacca gttttagggt ttggcatcaa gttacgtggt
      841 ccaaggacac gtccaagacg tccaacaaga gccatcatat caggtgtagc gataactacg
      901 tcgaagtcca accaaccgtc gttgatttta gcaacaaggt catcttcacc aacaaagtct
      961 gcaccagcag cttttgcttc ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa
     1021 gttttaccag taccgtttgg caataccatt gctccacgga tttgttggtc agctttttta
     1081 acgtcgatgt tcaagttgta agcaacttct acagttgcat caaattttgc aaagttagtt
     1141 tcttttgcaa gtgctacagc ttcttctaca ctgtatgctt ttgtgctgtc gattttctca
     1201 agagcagcac gaagttgttt gcttttttta gccattttct attctccttg taagtggttc
     1261 aatcgatttt catctcccac gtcacttctc gaaatgatga agtcttgcgg gttttcagtc
     1321 tactattttt ctcttcctac ggccttaagc tcccttgctg tatccaagta caagcctcag
     1381 tcacttgcct agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt
     1441 gattagtcaa caacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcattgca
     1501 gactctacgt ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt
     1561 gcacgagtaa ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct
     1621 gcagcttttt tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta
     1681 tcttcgtaaa ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg
     1741 ttgaactctt ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc
     1801 ggtggagctg gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt
     1861 ttagccattt ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca
     1921 caagtatgct ttacacatac ctttccatta tacactattt atctaaaaat gcaagagaaa
     1981 actttcattt ttaatcgaca taatcgccgc cttcaaagcc atagtactct tccaaactga
     2041 gaccacttgc agcaatttct ttggcttctt ttccaacgta gcggagatgc cattcttctg
     2101 ccatgtagcc agtctccttt tccttgcctt taagatagcg aacaacaaag ccatagtcag
     2161 ccgcatggtc caagagccac tgggctgcct tttcttcagt aactaaatcc ccatctgtcc
     2221 caatcaaatc aaaagcaaga cccgtctggt gttcactgta acctgggcgt gctgagtagc
     2281 gatctgctgc ttccttacca tcttgattga catagtcttg gtagagctta gcctgagttt
     2341 cataactcct aaacccactg tattggtcac tgattggata gccctcagcc tgcatagctg
     2401 cgattagttt gagcaactct gccttggctg ttggattttc tcctggattg taatcttttg
     2461 acaaaggata acgtttatta gctaggataa tctcatcgta tttcccttgg atactataat
     2521 agctcccttt attgctaact tctgcctttt tctgactaga agcttgagat ttgctaccta
     2581 cagttccttc cggttgactg ctttgctccg ttttttgagt gttttcttca actttggttt
     2641 tttcttgcga acaagctgca agggtcaatg ctagtaaacc agataaaatg acatatcttt
     2701 ttttcatttc tttcttcctc tctcttaggc caaatacttc tccaattcat gagataagat
     2761 tttaatcatc tcttccagct ctggcgattg tacttggcaa tcttctgccg ccatttcttc
     2821 ccagggcacc caccagactg ggccacggcc attcaaaccg tgactcttca tatcacctgc
     2881 tcttcgggga aaaagatgcc aatgagcgtg ggcatcgcca tttcctagga gttcaatatt
     2941 catcttttca gcctcaaatg ctttggcgac tgcttcttgg actaaactca tttcctctaa
     3001 aaagcgaagt tttacagaag tttccatatg atggagttct gtgacatgat cttttgctaa
     3061 aaataaggta tagcccttaa agtattggta gtcaccaata acaacatagc ctgtttctag
     3121 ttcttttaca aagtagggat tttgcccagc tttaatgagt tcgattctct gacagattaa
     3181 gcacattcta tgataccgcc tcgctcttaa gataagcatc aaccatacgc tcagtcgcta
     3241 ttactgaatc gatgtgggtg cgctcataag agtgactgga ctcaatacca gctccaagaa
     3301 gtgcatgctt gacctctgca cctgctgaca tcgctgctga agcgtccgat ccgtaaaatg
     3361 gatagatgtc gagcttaaat ggaatatctt gctctttagc caaggcaacc aagtgttgac
     3421 ggaagtcata gtgataagga cctgaagcat ccttgacaca gatagatact gtgtactcat
     3481 ctgtctgctg gtcatctccc atagctccca tatccacagc cagatattct actacctgag
     3541 caggaatgtt agaattagca ccatgtccta cttcttcaaa aactgaaaaa gcaaaatgag
     3601 ttgttactgg caattcaatc ttctctttct tataaatacg aagcaggttg agcaaaatcg
     3661 ctgcgctgac cttatcatcc aaatgacgag acttgataaa acctgtatca gtcacaacag
     3721 ttcgtgtatc gaagctgata aaatcaccga cctcaatccc aagagcacga gtttcttttt
     3781 cattgcttac ttttacatcc aaacgcactt ccatattgtc ctgcgtgcgt tctgcagttc
     3841 ctgcatcctt gtagacatgg caagaagttt ggtggatgag gatggttcct gatacctttt
     3901 gacctgtgct agccacatga acggtacagt tttcaccttc aatcatgttc caaggaaaac
     3961 caccgatacg gtccaattta agacgaccat ctggtttgac agcacgaaca atagcaccca
     4021 gcgtatccac atgggcagtc acatagcgat gttgctcatc attttgacct ttgatggtca
     4081 cattgacacc acccttagct gtgcgaactg gctggtaacc aaaaccttct agagtcttga
     4141 ctaaataatt cgaaatttca cgagtgaagc ccgttggcga tgcgatggct gtcagttctt
     4201 tgatatattc tactgtttga ttcatttctt cacctctttc gctacctatt ataacacatt
     4261 tatcatcgga taaaaaaaga aaatcactcc tgtagacttg gctacaaaag tgatttaagt
     4321 gattattcca tttcaaaaac atcgctttct tgcttgtttg gtagaaccaa tgagagcaag
     4381 attccaacaa tggctggcac caaccatggg agagatgcct tggcaaaagg aagaacgcta
     4441 acaagatttg caagaaactc aaccttaaac gagcttccta gtacgcttgc aatggcaata
     4501 actgtaacca cagcaattgt caactgcata cctggttttg aaagggcaac aaatttgttg
     4561 acaatgacaa tcataacgat agcaatcgtg attgggtaca agataaccag tactggaatt
     4621 gagtacttga taatcgcatc aagacccaaa ttggcaatag caaatccaat caaggtaaag
     4681 gctgtcgcat aaaccttgta gctgatttgt gggaagcgct cattaaagaa ctcagctgtt
     4741 gacacaatca aaccaacagt cgttgtgaag caggttacgg taaccatagc tgcaaggaag
     4801 agttgagctg ttgagccaaa gatttcttga gtggcttgtg acaagatgta aacacctggt
     4861 gttccaccct tcatcgcttc agctggtact gggaaatgat ttccaagaaa acctaaaccg
     4921 atgtaaagag cgctgaaggc aagggcaaca acgataccaa caacccaaat agttgaaatg
     4981 tattctttct tacttgaaaa tccaagttgt ttcaaggttt gaactgcgat tacgctaaag
     5041 gccactgaag caagggcgtc caaggtattg taaccttcta ggaaacctgt accaaaggca
     5101 gaagcttgat aagcagctga agcagcttga ggacttgttc caccatattt gatagctccc
     5161 agaacgacca agataacaat caaaattgca aagactggcg ttaaaacacg tccaatgcgg
     5221 tctaagattt ttgatggatt aagcgaaatc aaataggctg ccgcaaaata cagaaccgta
     5281 aatacaatca agccaagtcc tttatttgca tccgacaaaa gggggctaat ccctacttcg
     5341 taagctgttg tagcagtacg tggggtagca aagaatggac cgattgacaa gtaaagaact
     5401 gagaggtaaa gagtcgcaaa ccaaggcgct atcttcgttg aaatctcgta gatatatcct
     5461 ttaggattta gcgttccaat aataagggtc aagacggcga taccaacgcc tgaaaagaca
     5521 aaacctgcga tggcaggaag aaaatgttct ccagatagag cacctagaga aggcggaaaa
     5581 atcaagttcc ccgcaccaaa aaatattcca aacaggagca aacctgttag ggtacctttt
     5641 ttagccataa aaatctcctt catatttata aaatactgac ctagtatacc acgattagga
     5701 gtctgaaaaa agcatcacga ggcaaatatt aaatgttttc aattttctta aaaataagaa
     5761 ttatctaaaa ataaaactct cctacccagt ccacaccaag taggagaaat gcaaaatttt
     5821 aaagttcttc aaaggctaac atgccaccct ggacattgat aacattataa ccttgttcta
     5881 acaggaattg gcaagcacgc gccgatctca ttccagattt gcaaataata taatgcaagc
     5941 gatctttgtc caattaatca taactatcag ccaattgact aagcggtagg ttgtgggcac
     6001 attctaaatg aagagctgca aactcatcca cttctctcac atccactaga gaaagctggt
     6061 cgttttggta aagctggtaa aatgcgtcaa aggctatttc tttcattctt tttcttctaa
     6121 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtgcgt atgttaccga
     6181 cttcgtcagt tttatctgca acctcaaagc tgtactttga gcagcctacg actagcttcc
     6241 tagtttgctc tttgattttc attgactata aaatggtttt aattcttttt ttcaaatctg
     6301 gcactacttc tgcctcaaac caaggatttt tggccatcca gatttgattt cgtggtgatg
     6361 ggtgaactag cggaaaatag gctggcagat agtctttata gtgtttcacc ctctccgtta
     6421 ccttcccact gattttctcc tgtaaatagt aggcttgggc atattgccca atcaagaggg
     6481 ttaactgaat atcaggcaat tcctgtaaga gctgcggatg ccatttttct gcaaaacctg
     6541 tacgaggcgg aagatcaccc gacttgccat gtcctggaaa gtagaaatcc ataggcaaaa
     6601 cagcaaaata acctgaattg taaaaggtat cttcatccac acctagccag tcccgcaagc
     6661 ggtcaccact tttatctttc cagtaaaggc ctgcttcttg agttttaagt cccggagcct
     6721 gaccgatgat attgatgcga gcagtttttg gcgctgcaaa gagaggctca atgccacgct
     6781 ctgtatagct ggcattctgt gaatccgcca tgatagcctg tttgattctt tcgatttgag
     6841 acatctactt tccctccaaa aagaagtcca agcataagat ctcagacttc tatcgtttta
     6901 tttgatcaat tcgtaaatag cttcggcata gattgctgct gctcggaaga gatcgtccaa
     6961 ggcgataaat tcattggctt ggtgcatggt atcaattgag tctgggaaca tagcaccata
     7021 ggcaactccg cgctctaaca agcgaccaaa ggttccacca ccgatgactt gttcatgacc
     7081 tttaaagcca gtttgttttt catagatatt caacaaggtt tgcacaagtg gatcttccat
     7141 tggcacatag tgaggcgtgt gaccgtgttc agacaggcta acagaaacaa ctggcaagtt
     7201 ttcaaggatt gacttgattt gttctggact tgttcctttt ggatagcgga tgttgagggc
     7261 aatggtatta tcagcacttg tttcatcgaa gcggaagacg ccggcattca tagaaagagc
     7321 acccatcttt tcatccacat gagcaatctt aagattttca ccctcatgat cgttcaagag
     7381 aattttacct gcgatgtcaa ggtagtcttt ggctggacca gcaaagccaa actgactgag
     7441 gaagagggca aggtaagttg cgccattgac acctgaagca ggcatagcac cgtgggctga
     7501 tttaccaatg atcgtcacct tgtatttgcc agcttcttct tggagttctc ctctaagttt
     7561 gtgttctgca acaaaggcat ctagtttagc ttgcaagtca gccaagtcac ctgaaacgac
     7621 tgctgttgct gattctggta ccatattttc acgtaaacca cctgtaaagc tgtgaagacg
     7681 ggcaacacct gtattttctc ctgcaaagtg gaggtattcc gtgatatttc ctttttcacc
     7741 attgatgatt ggaaattcag catctggtga gaaaccgaaa tctggtttgg caagtcctac
     7801 gtgctcaaag tagtagtcca tgtctgccca gcctgattct tcgtctgttc caacgatgaa
     7861 gcgaactttc ttagaagttg gaagacccaa ttctttgatg attttcaaac catagtaaca
     7921 agctgttgta ggacccttat cgtccgaagc cccgcgcgca taaaggcgac catctttgat
     7981 agttggtgtg taagggtctg tgtcccaacc gctaccagca ggcaccacat ccatatgggc
     8041 aaagattccg agaacttctt ctccatcacc aaactcaaaa tgtcctgcat agttatcaac
     8101 attcttagtt gggtagccat cgcggtctgc gatttcaagg aatttctcca aggcttttac
     8161 tggaccaggc ccaaatggat gctgggcatc agccttgctg tcatcacgtt ctgaattgat
     8221 ttccaaaagg ctaaacaagt cagccaagag gtcttctttg cgtttttcta cttctgctgt
     8281 aaaatcaatt gctgtcattt tttcttcttt ctatcttttc tcgatgattt catctactgg
     8341 caagcggtag cttggttcca atttttcgtc tgtataaccc actgtgatca agagttctgg
     8401 gcggaaacgg tcttcgattt ccaaaacttc attaactttt gatttgtcaa aaccaagaat
     8461 aatgttagaa ccaattcctt ggtctgtcaa tgcaagaacc aagttcatgg caaccaaacc
     8521 tgcattgaga gctaggtagt cgctgacttg ttgttcattg tagcgtgcaa attcagctgg
     8581 caaatttttc atgaagtatt gaagttgttc ttctgagaaa ttgttagcac caccaactcg
     8641 ggcaatctta cgagcgcgtt tggcaaggtc tgtatctgta aatagggcaa tggttacagg
     8701 tgctgatgat acctgctcaa agtttgaacc ataagccaac tttgccagtt cagcattttt
     8761 ctcacgaaca actacaaatt tccaaggctg gctgttgtgg gcgcttggcg ccaaggttgc
     8821 aatttcgata gccgtacgca catcttttgg atcaacaggc ttatcagtga aatgcttggt
     8881 cgcatgacgt tttttattta attcaagaaa tttcataatc gatttccttt tctaattcta
     8941 ctgcttccat tctaccataa tttgaaagag cttgcaggga tttttcatga ttaagttttt
     9001 ctatcacaga cataaaagat atatattggt ttatcaggaa agtttctgat aaactagcaa
     9061 gtactttaca tttgaatgga gacagtatga aaaaatttag cctattacta gctatcctac
     9121 catttttggt tgcctgtggg aatcaagcta cacccaaaga gactagcgct caaaagacaa
     9181 tcgtccttgc tacagctggc gacgtgccac catttgacta cgaagataaa ggcaatctga
     9241 caggcttcga tatcgaagtt ctaaaggcag tagatgaaaa actcagcgac tacgagattc
     9301 aatttcaaag aaccgcctgg gaaagtatct tcccaggact tgattctggt cactatcagg
     9361 ctgcggccaa taatttgagt tacacaaaag agcgtgctga aaaatacctt tactcgcttc
     9421 cgatttccaa caatcccctc gtccttgtca gcaacaagaa aaatcctttg acttctcttg
     9481 accagatcgc tggtaaaaca acacaagagg ataccggaac ttctaacgct caattcatca
     9541 ataactggaa tcagaaacac actgataatc ccgctacaat taatttttct ggtgaggata
     9601 ttggtaaacg aatcctagac cttgctaacg gagagtttga tttcctagtt tttgacaagg
     9661 tatccgttca aaagattatc aaggaccgtg gtttagacct ctcagtcgtt gatttacctt
     9721 ctgcagatag ccccagcaat tatatcattt tctcaagcga ccaaaaagag tttaaagagc
     9781 aatttgataa agcgctcaaa gaactctatc aagacggaac ccttgaaaaa ctcagcaata
     9841 cctatctagg tggttcttac ctcccagatc aatctcagtt acaataacac tcttcgaaaa
     9901 tctcttcaaa ccacgtcagc tttatctgca acctcaaagc tgtgctttga gcaacctacg
     9961 gctagcttcc tagtttgctc tttgattttc atattgagta taagatatat taaaagcgat
    10021 gggatcagcc aatcgctttt ttagtttgca ttggttattt taggaaactc ttacaaaaaa
    10081 tcaaaaaaat tcttcacatc ctctacatac ctatgctttt ctattaagct tgctaatagt
    10141 tccagattgt gcctctgata gttatcttca cgacgtagtt cttcatacat ttcgataaag
    10201 ggaaaaccct tggatttggc aaattctaac tcagcctcgt aatcataagc gactttacga
    10261 aataggatat ttaccaattc cccatcttca acctctatca cggcatactg ggcacggtga
    10321 ttttttaacg cctcccaatt aaaatagggc atgccaatcg accctggatt gatgatttgt
    10381 tgcccttgac taccataacg aagcaactac ttgtgaacat gaccataaac tgccacgtcc
    10441 gtttccgcat ctagcagttg gtcaaatttc tctgtatcat tctcaactag caagtcacca
    10501 ccatagtttt tgtcaggtaa attatgagag atagaaaagc gcaatccgtc aatttctttc
    10561 ttttccagca aaggcaagct tcgtagccag acaatcgttg caggatccat tcgctccatc
    10621 aaatactgtg tcatacgcaa gagctgaact tcctgtgggt cttctaagcc atattgccca
    10681 tctaaagcct caaggacaca atcatcccaa ttgcctcgaa cacttgccgt gataggaagt
    10741 tcctttaaca gagcgaccaa gtcatttgca cctggaccag ggaggaaaat gtctcccatg
    10801 agccaatatt cactggctcc ttgagtttta gcatctgcaa tcactgcttc tagcgccgtc
    10861 gcattgccat gaacatctga taaaattgcg attttatggt ttattgtggt ttccttccgt
    10921 ttggtaatct actctttctt ccgccacttg aagcaagatt tctgtttcct gcgggttcaa
    10981 cttggtttgc acagcctctg ctactgctct tggtactcca acttcgacaa tctcatccac
    11041 actggcttcc ttgattttgg tcagagactt gaagtgcctc atgagatttt gcttgcgttt
    11101 aggtcccaga ccatcaatcc catccaattg agatgagaaa gaatttttgg agcgcagttg
    11161 gcggtggaag gtaatggcaa agcggtggac ctcatcttga atgcgttgga ggaggaaaaa
    11221 ttcctgagaa ttgcgagaca agtccaccac ttccagcgga tctccaaaga gcaattcatg
    11281 ggtttggtgc ttatcattct tttgcagacc tgcaattgga atatccaagc ccagttcttc
    11341 ttggatgact tgcttagcaa tattgacttg accttgcccc ccatcaatca caatcaaatc
    11401 tggaggagtc aaagcctcac gctgtactcg accatagcgt ctgcgaatga cctctcgcat
    11461 actggcatag tcgtctggcc cgactacggt cttgatttta tacttacggt aatccttctt
    11521 actaggcttg ccgttgacaa agaccaccat ggctgaaaca ggactagttc ccatgatatt
    11581 ggagttatcg aaggactcga tgcgaactgg ggttgggatt tgaagcaagc gtcctagatt
    11641 ttcaatagct ccttgggtct tctcgacaga tttctctagc aggttgaact tctgctctag
    11701 gctaacacgg gcatttttta tagctaaatt gaccagctgc tttttctctc cacgttgagg
    11761 cttaagaatc ttggaatcca ccaaggcctt gacagcctct tcgtcaatat cttgcggaat
    11821 cagtacctca ttgggaacta gatgggattt ttcttgatag aattgtccta cataggtcaa
    11881 aaaatcctca tctggatcat tgaagtaggg gaagagattg acatcgcgct cgatgagctt
    11941 accctgacgg acaaagaaaa cctgcacaca catccagccc ttatccacat agtagccaaa
    12001 gacatcgcga ttttggagat ccttagccat gacccgttgc ttggttcgaa gcgttccaat
    12061 agcctgaatc aggtcacggt attccgccgc acgttcaaac tccatagtct gggctgccgc
    12121 tgccattttg ccctttagct catcaatgat tttgttatcc tgccctttca gaaaatcaga
    12181 aacctcctgg gccatagact tgaaataagc ctcatccttc ttacagatgg tgtgggccat
    12241 gcattgaccg atatggtaat aaaaacagac cttagagggc gggttggtac acttacgaaa
    12301 agggaatatc cgatccagca accgcttgat ttcattggct gcccccacat cgggataggg
    12361 tccaaaataa agacttccgt cctttttgac ctgacgagtg ataatcaagc gtggatagcg
    12421 ctcattggtg attttgatga aaggatagga cttgtcatcc ttgagcatga tattgtactt
    12481 gggcttgttt tccttgatca ggttgatttc taggagaagt gcctcaatat tagactccgt
    12541 aacaataaat tcaaaatcca caatttcaga caccagagcc tctgtcttgg tatcatgact
    12601 tccacgaaaa taggaccgta ctcgattacg cagattttta gcctttccta catagataat
    12661 ggtgccattt ttatccttat gaatgtagca accagggctg gtcggcaaga gctctagttt
    12721 tgatttaatc aagttgttca tagttccatt atagcaaaaa aagtagggaa agatagtacc
    12781 ctactcacta gtctcatata tttttcggag gtttgcaaca tcctcttcct ggataccata
    12841 aaaggaacct gctggttgca tgacagactt ctcatctgta tggtccaagc caatcgcatg
    12901 acctaactca tgttctgccg tatggacaag gcgttcatag gagtagccat agtatggatt
    12961 ggacaaataa taatgattca accgcaccgt tacggacaag aattgccctg ttaagagatt
    13021 agtttgactt tccgcctctc ctgccacagg agtgcctccg tcgttcatct ccgtagccgt
    13081 aatatccgcc ttactagact cagtcacgag ttcaaagtta aaagcaccag tttgattcca
    13141 gttctggatt gcttctaaat aagcctcttg aaagcgtgaa tccatctgcg gatccaggta
    13201 aatacgagca gaggcctgtg cccaccttcc ttcagaatgc tggtgactat ctgtctggct
    13261 taacttaggc agttgccctg ttttctccca gtggtcaata ctttgttgac caatttttac
    13321 tgaccgttct gcttgcttta gcgctccttg aaaatctccg ttcagatacc agagaagtcc
    13381 gaaagcaagc acacataaga gcacaactat ccaaaccaga cgccaaaaca aacgccacac
    13441 aaaagaaaag aaagccccta tcaaacgaaa aagccagcgc atgtctctcc acctttctag
    13501 caaataagaa ttattttact aaaagaagct aaaagaaatc taaatactga ctttttcatc
    13561 ttaacgtcct actatttttt tgagtaactg gatagctttg tattttaaag gcgatggatg
    13621 gtaacggaaa gtacctgctt tgcgtacaat atagccatta aaattctgtt taaaacgcaa
    13681 aacaccatca cttccatcaa aaatcccttg aatgcctagg aagttgtatt taggtattcc
    13741 acgttttatg ctttccaaca taacatattt ttgaagcagt gcaggggcat agaacttatt
    13801 aaactcagtg taggaaccac taaagagata agtcgtttcc tgaggcatat aaacaaataa
    13861 actcccagct aaaacaatat cttcttctcc atatttttca atcaagtctc gcgcttctgc
    13921 ttttcgaact tcaaacgttt caaattgact agaatattct ctcagttgat tttgtttttt
    13981 ctcagaatga ggatttttac tcaaatcaag tcgcaacttg tccaagtttt cttctagttt
    14041 actttgttca ccttgcaatt tgctcatata gtccgaaaaa tttaagcttg ctatgagaaa
    14101 ctccgcttgt tctccaaaag tatcataaaa atgctcataa tattctaaac ttttatcact
    14161 atattctcta cgttcagagg tttcttttgt tatattctta aaaatcgata gttcttcacg
    14221 ttttaacttt ttcaaccgaa tgccaaaggt ttcagccttt ttcaccaagg gtttaccctt
    14281 tttgctaaaa cttttaagca aactcttttc agttaattca gttaaatctt tatagtataa
    14341 ccaatctggt tctccacctg ggtaacctgt tgttaagcca tcaaattgat aacctaaatc
    14401 agtcaaatct tgaataatac tttttttctc agcatctatt ggattacctt ggctatcaaa
    14461 agtttgataa gtttcatagg gttttacaag caactctaat acaccatttt gcttggcata
    14521 ttcttttaac tctgcataaa aaactggaag agcatcttgt tgggtataaa tcggccccga
    14581 attgagttcc atatgcagac cacccagcat gggcaggcta taaaccagag ctgcaacttg
    14641 aatttctcct tcttgtttca aagcaagata aacaattcga gcccctcttt tttctagcaa
    14701 atcccccatc tggacagatt gcataaagga acgagaagaa acctgatcag aataagtctg
    14761 aaactcttct ttcgtgagtg ttgttagtgc catatactta ctttctatgt ttttttctta
    14821 atgttttacg gaaatcaaga gcaagtctta acagaggata gagaggatga gtgggcattg
    14881 taaattcacc caagtattct tcaatcgttg gattaaattt ttccttaaaa tgataaagtc
    14941 caccattgag agagttttca acaccaccta aattttgcca gatcatacct cgttcaaagg
    15001 catagcgagc cgtttcatac caagttaaaa ttggtgcatt gtaacgttta aaatcatcat
    15061 ccataccagc atatatattg acagaggtag taccaaattc caaactcaaa gtagccgcta
    15121 aaggaactct cgcttgacct acatctatat attcctgcaa gaaggtcaat tcctctaaca
    15181 aacgttcttt ttccttcttc tgcgcttcta cttttgaagt tcgagtcgac tcagtaaagg
    15241 tctcttccaa ggctctattt ttcgctaact gttcttctaa ctcttgcgaa cgtttagaaa
    15301 catccaaggt ggccaaggtg atataggcct tgtccttaaa attatctaac aattttttat
    15361 aataggcttc attcctcaaa tgaatctctt ttcgcttctc agtttttttc atcaactccg
    15421 aaaatgaatc taatagttcc agtccaccat attgaatctc aagccctttg tttcgtgctg
    15481 ttcgaatagc ctgttttgtt gacttggaaa gtttatcttc ttcaaaattt tccttgtata
    15541 ttttcgcctg aatacgaggt tgaatggtgt ctcccatttc ctccgttttt cctgaccacc
    15601 ttactcccat ttgttgcaaa ctatcaataa tagccagatt ttcaggaaat tctgtctttt
    15661 cctgattgat taaactttga gataggcaaa tacttgggtc aaaagtcaca aaaaccgctc
    15721 tcttactgcg agcataggac ttaatagact gaatggcaaa attcaagagt tctttatccc
    15781 cataatccaa tataggtcct cttgggatgt aaaacatttt atagcctagc ggaagagttc
    15841 taatcaaaat actagctgtc gccagtaatt tttcttccct gtaaacacca aacttctcat
    15901 gttgccaatt agacttaact tcctcccaag cactactttg taatacattg gctaattcat
    15961 gttctttgac aaactgatca tattctaatg tgggaatgcc aatttgataa cggtacattt
    16021 cctactctct ttcctccagt attttattac tattctacta ctttcgtttg aaaagtctag
    16081 tgaaaacata ttttatttta gttctactcc ccctatgctg aagttcaaac taagtcagtc
    16141 tctcttctaa tttgaaatca attggtaggg ttgttaaaaa aacttccaat tgtttttccc
    16201 agtagtacca ctcgtgagtt ccagcgctat ggctataggt cacatcaaaa cctagttttt
    16261 tgagattttt cactgcgaaa ttattggctt cgtacaagaa atcctgttcg ccacaccacg
    16321 cccaaagttt ggtcttttta tccgattttt tagccagact ttcaagagaa tagggactag
    16381 ttgtccagtc tttaatctct ccaaaaacac ctctccagta ggctggactt cccagatttt
    16441 gactttcagg agaaaagttt tgaaagctga gggcacctga aaaactagct gcatgagaaa
    16501 aacgatttgt cgcaagagcc agtttgaagc agccgtagcc tcccatagaa agaccagcga
    16561 taaaggtctt ttcacgcttg ctagtcatat tagggaagaa gcgtttcaga acctgtggca
    16621 attcctctgc tagagccgtg tagtagtcaa aaccatactg ggtatcggta taccaaccat
    16681 tgctggtatt gggcataaca acgatgagat tagttcctcg aagcaagcgt tctacattgg
    16741 tccgcttaag ccaactatta tgatttccag acatcccgtg caaaaggtac aagacgggaa
    16801 tatcttcaca ctctggttct tccactcgat tggcatcagg gtagaggaca ttcacccccc
    16861 actccatatc caatacttgt gagtaatact cgattttcat tactgccatg attttctcct
    16921 tctatttttc tataagaaaa agccgaaact cgactttctc tctgtttatt tcaacgatta
    16981 ttttgcttcc atgactactg gtaaaatagc tggacgacgc ttggtttggt caaagagata
    17041 cttggtcaaa ttatctcgaa ccttcccttt aagatctgcc cagtcaaagt catctccttg
    17101 aagataatct tctaccgttt ggttaatcaa ttctgaactt tcacgtagaa tatcgcgact
    17161 cttcttgaga taaacaaatc cacgcgtatg aacacgagcc ctagccacaa ttttcttctc
    17221 acgacggttg actgtaatag ccacgatgaa aattccatcc tctgacaaga ccttacggtc
    17281 acgaagaaca acatttccaa catcaccaat ggcattccca tcaatcaaga tatctcctgc
    17341 tgaaaccgat ccagctggaa caaagtctcc attctcgtaa gccatggtcg tccccttttt
    17401 aggaatgaag atgcgttctg gcaacatccc aactgccatg gcagccttag cgtgagcatc
    17461 caactcacga tactctcctt ggacagggaa gaggtactta ggttgcaaaa gattgatcat
    17521 cagctgcaaa tcacgcacat ttccgtgccc tgatacatgt aaactttggg taatcaattt
    17581 gacaacccca cctgcctgat aaatcatatt ttccacacgc gcaacaaagg cttctttagc
    17641 aatagacgga gccgtagcaa tatagaccag gtccccatcc ttgatttcta cataacgatg
    17701 gcgaccaatc gacatcttac gaagtccatt gataggttca cccatacgac ctgtctcaag
    17761 aataatcaac tcatggtctt caaagcgaga catatcttta ggcttaatca agagaatttc
    17821 gttggctaaa gacaacttct taagacgaat cgctgtgcgg acgatatttt caatatcaaa
    17881 tcctgtcaag acgatacgtc gacctgtttt atccgcagcg tcaaaaatct gctgaatacg
    17941 agaaagatta ctggaaacag ctgcaacgat gatacgacct tcccagtcag caatagtttg
    18001 ggtaatttca tccctaactt cactttcact agccacctga atattgctgt ctgcattggc
    18061 cgaatcactg aggagagcca ggacgccgtc acgaccaatc tctgccaaac gagcaaaatc
    18121 agttgcataa gattcactag ccgtttggtc aaatttgaag tcacctgtat aaacgatgct
    18181 tccttccgat gtcttcaaga caattcccag actctctgga acggagtaag tcgtagggaa
    18241 gaaggaaacc actgtcccac caaaatcaat ctccgtattc tcatcaatga catggaaatc
    18301 attaaatttc ttaacggcat catttccttt gacaaagagc tttgccaact caatggtcaa
    18361 ctcagaccca aatacaggaa ctttagcctc tgccaagaga taaggtagag caccaatggc
    18421 atccgcatgc ccgtgggtca agaaaacccc agcaatacgg tcgctatttt caaaaaggta
    18481 atccatgttt ggaatcacca catcgacccc taattgttca ttttcaggat attttaaccc
    18541 tacattcaaa acaaaaatgg actctccaat ttcagcaatg tacatatttt ttccattctc
    18601 acgcacacca ccaagtgttg ttaaactgat attactcatt tttcctccaa aatcttagtt
    18661 tatcttgatt atagggcaac tctaccctct tattctaaaa gttctaatac tttcagccga
    18721 atcttttcct accattatac catttttttg atgattttca aaatgaaggt ctgttttcaa
    18781 aaaagagttg atttcccaac tctttcctaa cttctactct ttttccatca aaaaatcata
    18841 aatttcttgc accgtaccca gcgccatcat ttcttggtct ttaacggttt gtttgagatt
    18901 ttggtaaatt tgactttctc ctatctcccg ctttggcgcc tctttattga ctgtcatcac
    18961 accatctttt atcgtcacaa agcctagttc ttcaaatact tgaatcatct tgaccagcaa
    19021 gatttgttga atattaagat atgcagccaa atctttcagc ttgtagcgaa tatcaaactc
    19081 tgggaactgg taaatagtct tgtacaattt ggcaaactga tctctagtcc cataacctgt
    19141 cagataatag gccttgtcaa tatcattttt gaaatagaca gcagagaaat gctgttcctg
    19201 aaaaatggtc ttcagctgag taatatcctc tggaatgttt tttacgacaa cagcttcact
    19261 agccgcaaga tttggcagtt ctccaggaaa atccaagact ggaacacctt ctggcaagac
    19321 tgcatttttt ccacgaatgt taaaaagttg aacaccttcc actcgcgcat ccatcatcat
    19381 caactggagg gcagtttggc cgttccattg gttgacagac aatttaaccg ctaactctag
    19441 attcttggtt tgagaaaact ctgtcgccca tctgccttga ccaaaggcta ccacttcaaa
    19501 actcacctca cccttggaaa ttttcagctt tagatgggca ttacctgccc ccatagtacg
    19561 agcactttcg acctgaaaat tcttgatata aaaaataggt ttctgattat ccattccaaa
    19621 aggagctaaa cgttcaaaac ttttgaccgt ttccaagcta agtgcctcca aatccaactc
    19681 ttcatctagg tttaacttat tcttgccacc agcatctgca cctttttcac gaacataatc
    19741 ttccaaaatc tgagataaat ctgagagttg ctcaacttcc agcgtcatac ccgctgcacc
    19801 tgcatgacct ccaaaggcga tgaagaggtc tcgataggga tccagagctt caaaaatatc
    19861 gaccgcttcc acactacgag cactgccctt ggcacgaccg tcttctatat taagaacaat
    19921 gactgtctgt cccaattctt ccaataaacg accagccacg attcctagaa ccccaggatt
    19981 ccagccttcc ttggccaaga cctgaacctt cttctcagga tccaccatgg tcttggcttc
    20041 ttcatagata gactgaacga tttccttgcg ctcttcgttt ttctggtgaa tcataagggc
    20101 aatctcatgc gcttcctcat catcaaatcc agtcaacaaa tcaatggcag gattgggatc
    20161 atccaagcga cccaaggcat tcaaacgagg agcaatctgg aaaccaaccg tttcttctgt
    20221 tacttcgtta gcagcaatcc cagccatgtc cagcatttct tgcagaccaa tgcgctgggt
    20281 atgacccaac atttccagac catattgaac taagatacga ttttcatccg tcagactcac
    20341 catatctgca atagttccaa tagcgaccaa atcaagcaat tccacttgca cttcttctaa
    20401 cagggcacaa gccaacttga aagcaactcc acaaccagcc aaatatttaa aaggataatc
    20461 cgcatctgga tgttcaggat ggacaatagc ataagcatct ggcagggttt caggtatgga
    20521 atgatggtct gtcacaatga catctactcc catagactga gccaatgcaa tagcctcatg
    20581 accagcaacc ccattgtcca ccgtcacaat caaggaaatt ccttcttgct cgataaagta
    20641 tttataaaca ctagcattag ggccatagcc atcggtaaaa cgatttggca ggtaaactcg
    20701 gcactccgca ccaagttgtt ccaaactttc cttcacaata gaagccgaag tcatgccatc
    20761 cgcatcatag tctccataaa cgagaatatt ttccccttct tcaatagcct gacgaatccg
    20821 ctccactgcc ttgtccatat catggagcag ataagcatca tgtaagtcct ccaaggaagg
    20881 ttctaaaaac ttcttcagac tttcttggtc ctgaatccct ctctcaaaca ataaccgagc
    20941 cacctcagga cccagtccag ccttcttggc tatctttgta aaatccgcat tttctacctg
    21001 cagggcaaac tgccattcat aagtaggtgt tatcaaaaag acatccactc tttctaagaa
    21061 ttctattgct tcattataac atgatttaga cgttttctct atccagattg cttttttata
    21121 acattttata gtatattgaa actagaatag tacacctcta cttctaaaat attgttagaa
    21181 atcgatttga ttgtcccgat cgatttttcc tgttattata tcactatagt gaattttttc
    21241 agatatgatt tgacaagaac attcttttat cgtagaatca tgttataaaa tctaacacaa
    21301 gggagatctc tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac
    21361 cacgcactcc gcaacatcaa tctccgtttt gaaaaaagga caagttgttg tcctgcttgg
    21421 accttctggc tctgggaagt ccactcttat ccgtacgatc aatggtttag aggctgttaa
    21481 caaaggaagt ctcctagtca atgggcacca agttgctggt gccagccaga aagatttggt
    21541 acctcttcgc aaggaagtcg gcatggtttt tcaacatttt aacctttatc cacacaaaac
    21601 agtgttagaa aacgtaacac ttgcacccat tgaagttcta ggaattgata aaaaagaagc
    21661 tgaaaaaacc gcccaaaaat atctggaatt tgtaaatatg tgggacaaga aagattccta
    21721 tcccgccatg ctatctggtg gacaaaaaca gcggatcgcc atcgctcgtg gtcttgctat
    21781 gcatccggaa ctcctcctct ttgatgaacc aacatctgct cttgatcctg agactatcgg
    21841 agatgttcta gcagttatgc agaaactggc gcatgatggg atgaacatga tcatcgttac
    21901 ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt atctttatgg ccgacggaga
    21961 agttttagta gatatgacag atgtcgatag cttttttgac aatccaagcg aacctcgtgc
    22021 ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat aaggaggcgc
    22081 ctatgaaaaa aaattctttt tatcagcatt attgattagc cttttcggcc ttgttgctgc
    22141 caaaccagtc caggctaata ctagtatcgc agacattcaa aaaagaggcg aactggttgt
    22201 cggcgtcaaa caagacgttc ccaattttgg ttacaaagat cccaagaccg gtacttattc
    22261 tggtatcgaa accgacttgg ccaagatggt agctgatgaa ctcaaggtca agattcgcta
    22321 tgtgccggtt acagcacaaa cccgcggccc ccttctagac aatgaacagg tcgatatgga
    22381 tatcgcgacc tttaccatca cggacgaacg caaaaaactc tacaacttta ccagtcccta
    22441 ctacacagac gcttctggat ttttggtcaa taaatctgcc aaaatcaaaa agattgagga
    22501 cctaaacggc aaaaccatcg gagtcgccca aggctccatc acccaacgcc tgattactga
    22561 actgggcaaa aagaaaggtc taacctttaa atttgtcgaa cttggttcct acccagaatt
    22621 gattacttcc cttcacgctc atcgtattga tgccttttcc gttgaccgct ctattctgtc
    22681 tggctacact agtaaacgca cagaactact agatgatagt ttcaagccat ctgactacgg
    22741 tattgttacc aagaaatcaa atacagagct caacgactat cttgataact tggttactaa
    22801 atggagcaag gatggtagtt tgcagaaact ttatgaccgt tacaagctca aaccatctag
    22861 ccatactgca gattaaggag gacaccccat gacagattta tcatcttgga cagcctattt
    22921 tcaggatttt ggacaatttt tcaatggttt cctctttact cttgccctag cgattggatc
    22981 ctttatcctc gccatggtct taggaatctt ctttggtgcc atgtcaacca gtaaacgtcc
    23041 aattttacgc attttagctc gcatctttgt tgaattttac caaaatactc ccctcttggt
    23101 gcagtttgtt attgtttttt atggcctacc tcttatcagt gaccatatca tcatgattcc
    23161 attttattgg acagccgttc tctgcgtggg actctatcac ggcgcttata tcgctgaggt
    23221 tattcgttca gggattcagt ctattcctag tggtcagatg gaggccgcct tgtcgcaagg
    23281 ttttacctat atcagtgcca tgcgcttgat tatcttgcct caggccttcc gcatcattct
    23341 ccctccattg accaaccaaa ttgttaacct catcaagaac acctctactg tagctatcat
    23401 ctctggagta gacttgatgt ttgtgactaa gtcttggtcg gctctcaacg gaaactatat
    23461 cccaggcttt ttaggtgctg ctcttctcta ctttgcccta tgcttccctg ttgcccagtt
    23521 tggtcgcaag atggagcaag ccaacaaaaa agcctattca ctttaggagg ttactatgga
    23581 atctatttta gaagttttaa ccccagataa cctagtcttt atctttaaag gatttggctt
    23641 gaccctctat atttctctga ttgccatcat cctctctact atcatcggta cggtgctagc
    23701 tgtcatgaga aatggcaaaa atcctgtctt gcgaatcatc tccagtattt atatcgagtt
    23761 tgtgcgcaac gttcccaacc ttctctggat ttttactatc tttttggtgt tcaaaatgaa
    23821 atccacacca gcaggtatta cagcctttac tctctttaca tcagcagcct tggttgagat
    23881 tattcgaggc ggtctcaatg ccgtagacaa gggacaatac gaagtaggaa tgtcacaagg
    23941 cttcacctca gcccaaatcc tctactacat cattctccca caagccatcc gcaaaatgct
    24001 accagccatc atttctcagt ttgttaccgt gattaaggat accagtctcc tctactctgt
    24061 tatcgcccta caagaactct ttggagccag ccaaattctc atgggccgtt atttcgaacc
    24121 agagcaggtc ttcagtcttt acatcctgat tgccctcatc tacttcagct ttaacctagc
    24181 aatttctagc ctgtctcata tgctagtcaa acgttggcaa caagctgcag aataatactc
    24241 ttcgaaaatc tcttcaaacc acgtcagctt taccttgccg tatatatgtt actgacttcg
    24301 tcagttctat ccacaacctc aaaacggtgt tttgagcagc ctgcggctag cttcctagtt
    24361 tgctctttga ttttcattga gtataaacag ccactctcca gttcaattgg agagtttttt
    24421 gatgatagta gatatttata gacctcaatt tgacaccata cattttctat gataaaatgt
    24481 aacaaattta tttacaacaa atcgaaatct aaatgaaatg gaattttcta tgaaatcagt
    24541 caaaggacta ctctttatca tagctagttt tatcttgact cttttgactt ggatgaacac
    24601 ttctccccaa ttcatgattc caggactagc tttaacaagc ctatctctga cttttatcct
    24661 agccactcgt ctcccactac tagaaagctg gtttcacggt ttggagaagg tctacaccgt
    24721 ccacaaattc acagcctttc tctcaatcat cctactaatc tttcataact ttagtatggg
    24781 cggtttgtgg ggctctcgct tagctgctca gtttggcaat cttgccatct atatctttgc
    24841 cagcatcatc cttgtcgcct atttaggcaa atacatccaa tacgaagctt ggcgatggat
    24901 tcaccgcctg gtttacctag cctatatttt aggactcttt cacatctaca tgataatggg
    24961 caatcgtctc cttacattta atcttctaag ttttcttgtt ggtagctatg cccttttagg
    25021 cttactagct ggtttttata tcatttttct atatcaaaag atttccttcc cctatctagg
    25081 gaaaattatc catctcaaac gcttaaatca cgatactaga gaaattcaaa tccatcttag
    25141 cagacctttc aactatcaat caggacaatt tgcctttcta aagattttcc aagaaggctt
    25201 tgaaagtgct ccgcatccct tttctatctc aggaggtcat ggtcaaactc tttactttac
    25261 tgttaaaaat tcaggcgacc ataccaataa tatctatgat aatcttcaag ccggcagcaa
    25321 agtaacccta gacagagctt acggacacat gatcatagaa gaaggacgag aaaatcaggt
    25381 ttggattgct ggaggtattg ggatcacccc cttcatctct tacatccgtg aacatcctat
    25441 tttagataaa caggttcact tctactatag cttccgtgga gatgaaaatg cagtctacct
    25501 agatttactc cgtaactatg ctcagaaaaa tcctaatttt gaactccatc taatcgacag
    25561 tacgaaagac ggctatctta attttgaaca aaaagaagtg cccgaacatg caaccgtcta
    25621 tatgtgtggt cctatttcta tgatgaaggc acttgccaaa cagattaaga aacaaaatcc
    25681 aaaaacagag cttatttacg aaggattcaa gttcaaataa gtaatcatac tctcctggga
    25741 tttcccagga gaatttttta tagccaaatg aaataagacc ggaacgatgg aattttggca
    25801 ttcaaatcaa ttgataagaa tattttatag tggagtgaaa taggatacga acaaattgat
    25861 taggaaaatc aaatgaattt atagaaatct tttagcagtt atgttgtcct attctagttt
    25921 caaaacgcta tagaagcagc attgtgctag tctagattca gtttactata ctaaaacgag
    25981 tagcttgaaa tcaaaaaacc caccctcaca ggcaggtttt atctgtatta ttcagctaga
    26041 ttatgcttta ccttctgaac cgaatacgtc gatacgttct tcaaccgatg cttggatagc
    26101 ttttacaccg tcagtcaaga atttacgtgg gtcgaagagt tttttcttgt cgtattctgc
    26161 ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg cgatttggca
    26221 ttctgtgtta acgttaactt tggcaacacc aagtttgata gctgcttgga tttgctcatc
    26281 aggaatacct gatccaccgt gcaatacgat tgggaatcct ggaagagctt ctgtcaattt
    26341 ttgcaagtgg tcaaggtcaa gaccttccca gtttactggg taagggccgt ggatgttacc
    26401 gataccagct gccaagaagt cgataccagt ttcaaccatt gctttagcgt cttcgattgg
    26461 agccaattca cctttaccga tgattccgtc ttcttcacca ccgatagtac caacttcagc
    26521 ttctactgag atacctttag cgtgtgcttt ttcaacaact tctttagcca atttaaggtt
    26581 ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa cttcgataca
    26641 ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata gctactggta cagtgatacc
    26701 cattgattca acaaggttag cgatcaagtt gcgagcaact ttgtaaccac ccatgtattt
    26761 agcagcaccc attgaagttt ggatcaaaac tggagctttt ttagcttctg ctgcgcgcaa
    26821 gatagcttga gtccactcaa ggttgtttgt gttaaatcca ccaactgcat aaccgttgtc
    26881 acgggctgct tggacaaatt tttctgctga aacgattgcc attttatcag gcctcctgta
    26941 tatttttatg ggtcatccca tttacattgt tcattttatc actttttgcc aaaaaaatct
    27001 agtttttccc gcagtttcga ttgattttct tctaactcca tctatgtaaa ccctttctct
    27061 ccctagtctt ggacgacttt tggaaaatct ataaagaagg ttaaactatt ctcctccatc
    27121 tcgaaacgat aagctaattt ttcatgttct aatagactct taaccacaaa gagccccata
    27181 ccagacccct tgaccttgcg actggcattg tcagaaaaag actgggctag tttttcttgt
    27241 tcctctgagc tacagctatt ttcgataaaa agttctcctt ctctttctcc aattcgaact
    27301 aagccacctg gaacagagtg cttaatggca ttgctgatga gattagaaag aatcaacttc
    27361 ataactgatg ggtttagata agcctgctga tgggtcaaac tattgtctat ctggagctct
    27421 ctttccttgg ctagcaaggc ataatctttg accagatttt gcgtcatctg gaggaggtca
    27481 attgtttccc tatcatctcg caattcctgc acagaagaga gggaaagtat ctgcagaaca
    27541 tggtgattga gttcatccac aatccccaag gcaactccca gatactggtc tctatcctta
    27601 taacgaccga tattctctct catattttcg attaggattt tcaaactagc cagcggtgtt
    27661 ttcaattcat gagaagctcc tcgtaggaat tcgaccttca tcttctccag ctggagaatg
    27721 gcttcattct tttcatgcaa gtccgcaata acagtcaaga gatgctggta gaggctattg
    27781 atttgttcct tgagattacc tatctcatcc ttagaatcca cgcgcaatcg cacttgggaa
    27841 tccaggtcca tcatccgacg ggtcacccgc ttgatttcca aaatcggtgc aacaatagtc
    27901 cgagcgtaga tgtaggccac caaaagggaa atcagaaagg aggccagcaa ggtataggga
    27961 agaaactgga gactgatttg ctccgcttcc ttttgtaaat ccatggaagc tagaaactgg
    28021 agaatcatag taccaccgtc ttgcgttttc acctcgcgct cctcaataaa gagagaggtt
    28081 gtctggcggt ctgtgtccag aggaagactg tccttgactt ctaacttgtc ctcggtcatc
    28141 tcacctttga cggtcccctt gatatcacta gtctgggaat acaagtctaa cacttgctcg
    28201 atactctgcc tatctttccc ttctagggac tgggcaatgg ctgttgcctt ttgaccaatg
    28261 gtttcctgac gatgactcag ataagtcgaa ggaaaaagaa aataaatagc taaatgaagg
    28321 cagataacca gaacactaaa tatcgagaag gtatagataa atatctttgc aaataaacct
    28381 gttcgtttca ttttcgctcc aatttataac caacattgcg cacagtgagg atacaatcca
    28441 aatctagctt tttccgcaat tccttgatat aaacatcaat aacacggtca aagggaacct
    28501 catctgtcgc tttccagacg gcatcgataa tctgagatcg agtcaaggcc cggccttcat
    28561 ttttcactag atagtccaga atttccaact ctttggcatt gataggcact tcttgacctg
    28621 cgaggcttgc actgtagctt tcaaagtcca ccttggtatc cttgtaagaa aagattcgtc
    28681 ctgtatcgta gtagcgcttg aaaatcgcgt ccaccctcac ttttaaaagg gagagggaga
    28741 aaggtttttc cagatagcca tctgccaaag aggcaaaggc actcatcttg tattcctcat
    28801 cttgaaaagc tgtcaacatc aagacaggaa cctgactggt tttacgaatc tcagctagga
    28861 cttctaagcc gttgagcttg ggcatctgga tatccagtaa aaccagggcc acctcatagc
    28921 tagaaaattg ctccagagct tcctgaccgt ccgctgcctc aatagtttca tagccacaat
    28981 ccgtcaaata atcactgacc ccctcacgga tcatctcttc atcttctaca attaaaattt
    29041 tcatacttta actgctctct attttttatt tttcttagaa taaataccta ccctattttc
    29101 tattatagtc tcttgctggc cttttgtctg caagcaactg accactagat aaaacgttgt
    29161 gaaattcctt tctcataaat tccataactt tagtatatta tatttaagca ctaaagtaca
    29221 aagaaagcaa ctgaaagcaa tgattttcac cactgctttc ggatttattt tgaattgtta
    29281 aatagccatt cctatccact attcttgaat agaaacacaa gatgcaatct ttattctaga
    29341 ctcatttttt caaatttatt caccatccag caagagctct tttggttgtt ttctaaggag
    29401 attgcttgaa gcaagcgcca taacgagaac cactagaacc aaggcaagga caaaaatgat
    29461 gataaagtct gatgtctgaa tggaaatgtc taggctcgac aaggtcttgc taaagccatc
    29521 tacttctgca ccaccaccaa ggttagaggc ttgagccgcc ttactagcct gtttggcaac
    29581 acctgaagtc acattggcaa ggacagtgtt tccaattgca cgggcagtgt aattagctag
    29641 gaagtaagca gaaactagag cagggatagc aatcaagata gattcggtga tgaattgacc
    29701 caagatactt gcctgcttga ggccgataga gaggagaatt cccacttcct tgcgacgggc
    29761 gttgatccaa aggctgagca agagggcaag gaggagaact gagaagctca agctacccca
    29821 gaagaggagg ttggccatct tgtacatacc agagatagat tgctcaagag ctgggtagtt
    29881 agaggagctc ttgacgagtg tgtagctctt ccagttgata ccactgatgc cattcaactc
    29941 tttcataaca tcatccaagt tcttgtctgc tgttacaaag aaggttgcgt ccccataaat
    30001 ggctgtgtct tctgtgtatc cataaagttt tgcagcagtg tgaatgtctg taatagctgt
    30061 gttttcgtaa agttcttgtg agtaggttac tgctgactta ttatgaccat caaagagtcc
    30121 cttgattgtc acttcaactg tttccttggc tcctttttca ttatctgcat cgtagatatt
    30181 agagtccagt ttaaccttgt cccctacttt ccagccgtgt ttggctgcca agtccttgtg
    30241 caagaggatt ttatccttgt cgtcgttggt taagtgctct ccttcgacta gtttataaga
    30301 accagagaca aacttgtctt ctttagagga gtcattgaca cctgtaatca tcaagctact
    30361 tccaaaacgc ttggcacgat cagcagtgag attcttcttg gtttctggcg tttcaatcag
    30421 gtcatatcca gtcaaatctc cgatagcgtt gatacgtttg acataagact caatggcctt
    30481 gttttcggtg atttttttga tgtcttcacc cttgatattc ccagcaccac gaggcgttcc
    30541 ttggttgacg cgacgattga tttgcatgga gaagctattg gtgatatttt taaaggtctc
    30601 ctgagaagcc ttggcagtag ctcccttgat tgacaagccg accaaactca agctcgccat
    30661 gaggagaata atcaggaaga tgacaatcga tttgaaaaac ttccttgtaa cataggcaaa
    30721 tgcgttgtgt aacatagatt ccctttctag attttgtttt aatcattcta ttaaaataag
    30781 ctcaaattat ttactagtat tgcgcgtttc agtcagtttc ttatccttta attcaagtgt
    30841 aatatctgac gcttgtgcca cttctttact gtgagttacg acaatcacac atttacctgt
    30901 tttctgggca agtgatttga gtagttcgac aatatctcca gcagttttag gatccagatt
    30961 tcctgttggc tcatcagcta gaataactgg agcttctgag accaaactgc gagcaatggc
    31021 aacacgttgc tgttgaccac ctgataactg gagaacattc cgcttgatct ggctttcatc
    31081 caaaccaagc tcaagaagtg tatccttgct tgcctttttg ttgaccaagc ggatattttc
    31141 cagcggagaa agataatcta tcaagttata attttgaaag accagggaaa tatggtgcat
    31201 gcgatggtaa gaatagccct tcttacgaat atcctctcct tgaaaaagga tagaaccttc
    31261 aacaggacta tctagaccag caagtaggga caagagtgtg gattttcctg ctcctgactc
    31321 cccaataata ctgtaaaatt ttccgggttc aaaattataa tcgatctgat ataggactgc
    31381 ttcagcagta ttcttataac ggtaggtaac atcttgtaat tgtaataaag tcatgatttc
    31441 tccttcttaa ctaatagatg ataaaatttc tttcggtgat tttctaaata agaataggaa
    31501 acaaagggct acagataagc aactaagcag aactagaaaa acataggatt ctgcaaaaga
    31561 taagatgcta gttgataaac tgcttgcttt ggctagtgta tcttgtaagc ttgcctgatc
    31621 tccacttgct agtagagttt ggagtaggta agttgtgatt ccgtttcctg caacaaatgc
    31681 tggaagcaaa gctccaagag ataccaaaac tacctctaaa cagaattgta ggaagatcga
    31741 gctcttgcct tttccaagtg caagtaaaat ccccacttca tagacccgtt ctctcaacca
    31801 gagagacaaa accagaatta aggctccagc tcctgctatc aacatcccat aaaggaagat
    31861 ggtcaggaag gtttggaaag ttgcaactga gtctttgatt tgttcaaaag ccttgttttc
    31921 cttttcgact tggtagcctt gattttccaa ggccaagttt tctacctgct tcatgagtcc
    31981 gtccatttcc ttaggatttt ctacatagaa gcgtgctgca ctgacttgag cttcactatt
    32041 gcccaaaagg gtttggctac tttcatagtc tgtaaagact tgattttcac tgaagtcaga
    32101 agacaagcct gtgaatttct cttgtttttt accagaaaag atgccaataa tctcaaactc
    32161 tactgtttgt ccttttccag attcagactg accagcatcc aagccaatct tgtcatgaag
    32221 tgaaagaccg ttcttcttag ccaattcttc gtggataagg attttcttgg aatccccttt
    32281 ttgaaggtgt cgcccttctt ttagattgaa agccgaactg gtaaaggtta catccttgga
    32341 tgaatcctca agagccgtta agctaaccaa gttattgtct gcagctgata aatcatcacg
    32401 ctccacgctc tgctcgccag tcactgcttc cttgtctttt agttttgcga ccgtctcaag
    32461 ttcaggagag acattttcca gccccttaat cttgcttaca gatgctaggt ctgacaactt
    32521 gaatgtctga ccattctcta tcttcttaat agaaaaagat gtattgagtg atttataaag
    32581 attgctttct actgttttgt tggacttcat cagagtcaaa caggctgaaa ttccggccaa
    32641 taagaccaat aaaatcagaa ataaaataaa acttctcagt cgctttctgc tgacataagc
    32701 ccaagatctt tggattggat tcatttgtca cctccatatt tgtaagacta ttataaaacc
    32761 caaatatgaa atgtttatga aatacgaaaa aaaaaa
//
LOCUS       DAVLTG010000020        30796 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLTG010000020 DAVLTG010000000
VERSION     DAVLTG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.020"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            35..415
                     /locus_tag="VYN12_000993"
     CDS             35..415
                     /locus_tag="VYN12_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415401.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            609..899
                     /locus_tag="VYN12_000994"
     CDS             609..899
                     /locus_tag="VYN12_000994"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415402.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            950..1642
                     /locus_tag="VYN12_000995"
     CDS             950..1642
                     /locus_tag="VYN12_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1415403.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1695..4106
                     /locus_tag="VYN12_000996"
     CDS             1695..4106
                     /locus_tag="VYN12_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1415404.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4356..5057
                     /locus_tag="VYN12_000997"
     CDS             4356..5057
                     /locus_tag="VYN12_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415405.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5059..7767
                     /locus_tag="VYN12_000998"
     CDS             5059..7767
                     /locus_tag="VYN12_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1415406.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7863..8354)
                     /gene="tpx"
                     /locus_tag="VYN12_000999"
     CDS             complement(7863..8354)
                     /gene="tpx"
                     /locus_tag="VYN12_000999"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1415407.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8477..9406)
                     /gene="psaA"
                     /locus_tag="VYN12_001000"
     CDS             complement(8477..9406)
                     /gene="psaA"
                     /locus_tag="VYN12_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1415408.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9438..10286)
                     /locus_tag="VYN12_001001"
     CDS             complement(9438..10286)
                     /locus_tag="VYN12_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1415409.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10283..11005)
                     /locus_tag="VYN12_001002"
     CDS             complement(10283..11005)
                     /locus_tag="VYN12_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1415410.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11296..13188
                     /gene="pepO"
                     /locus_tag="VYN12_001003"
     CDS             11296..13188
                     /gene="pepO"
                     /locus_tag="VYN12_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1415411.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13311..13940)
                     /locus_tag="VYN12_001004"
     CDS             complement(13311..13940)
                     /locus_tag="VYN12_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1415412.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14936..17158
                     /locus_tag="VYN12_001005"
     CDS             14936..17158
                     /locus_tag="VYN12_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1415413.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17188..17631
                     /locus_tag="VYN12_001006"
     CDS             17188..17631
                     /locus_tag="VYN12_001006"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1415414.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17670..18084)
                     /locus_tag="VYN12_001007"
                     /pseudo
     CDS             complement(17670..18084)
                     /locus_tag="VYN12_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18103..18517)
                     /locus_tag="VYN12_001008"
                     /pseudo
     CDS             complement(18103..18517)
                     /locus_tag="VYN12_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18648..19294)
                     /locus_tag="VYN12_001009"
                     /pseudo
     CDS             complement(18648..19294)
                     /locus_tag="VYN12_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(19471..20121)
                     /locus_tag="VYN12_001010"
     CDS             complement(19471..20121)
                     /locus_tag="VYN12_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1415415.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            20233..21075
                     /locus_tag="VYN12_001011"
     CDS             20233..21075
                     /locus_tag="VYN12_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1415416.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21151..21588
                     /locus_tag="VYN12_001012"
     CDS             21151..21588
                     /locus_tag="VYN12_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1415417.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21656..21958
                     /locus_tag="VYN12_001013"
     CDS             21656..21958
                     /locus_tag="VYN12_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415418.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(22049..23122)
                     /locus_tag="VYN12_001014"
     CDS             complement(22049..23122)
                     /locus_tag="VYN12_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1415419.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEVFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23278..23955
                     /locus_tag="VYN12_001015"
     CDS             23278..23955
                     /locus_tag="VYN12_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415420.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23948..24922
                     /locus_tag="VYN12_001016"
     CDS             23948..24922
                     /locus_tag="VYN12_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1415421.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(24971..26914)
                     /gene="thrS"
                     /locus_tag="VYN12_001017"
     CDS             complement(24971..26914)
                     /gene="thrS"
                     /locus_tag="VYN12_001017"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1415422.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(26972..27295)
                     /locus_tag="VYN12_001018"
     CDS             complement(26972..27295)
                     /locus_tag="VYN12_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1415423.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(27726..27926)
                     /locus_tag="VYN12_001019"
     CDS             complement(27726..27926)
                     /locus_tag="VYN12_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415424.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            28163..28792
                     /locus_tag="VYN12_001020"
     CDS             28163..28792
                     /locus_tag="VYN12_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1415425.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28933..29202
                     /gene="rpsO"
                     /locus_tag="VYN12_001021"
     CDS             28933..29202
                     /gene="rpsO"
                     /locus_tag="VYN12_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1415426.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            30017..30631
                     /locus_tag="VYN12_001022"
     CDS             30017..30631
                     /locus_tag="VYN12_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1415427.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
BASE COUNT         9078 a         5711 c         6996 g         9011 t
ORIGIN      
        1 tttatttgaa aaaaataaaa aaggagattt tattatgaaa ttaaaaacac ttgctttaat
       61 tagtggtatc gtcggtcttg tgggaggaat tttacttctt attggtcctt ttgtcttgtt
      121 gggaacagcg gtaaacacag ttgctacaac tcttaatgga ggagctactg caggggcttt
      181 ttcaggtgtt gccttactct tgaatgcctt gaagattgca aatcttgttc ttggtatcat
      241 tgctattgtt tactataaag gagataatcg tgtaggtgca gctccgtctg tactaatgat
      301 tgtttttggt ggagttagtc tcattccatt cttaggatgg gttgggggga ttcttgttat
      361 tatcggagga tctctattcc ttgcaacatt gaagaaattc aaatcagaag aataaaaggt
      421 attttagcat gaaaagaata aaaacgttta tcggtatagg agtagctcta ttatctcttt
      481 ctcttctagt tgcatgtgga acataaagtt caaaggatac ttcaacaagt aatgatgaga
      541 agacagtagc aacatccaat agttcaaaag aaacaatcac tttcgataca ccggttgtaa
      601 cagacgatgt gattgaatca atacgcactt atgcagatta tatagatctt tataaaaata
      661 tttttgatga ttattttact aaagctgagg aaggtttcaa aggcacagct atggaaaata
      721 atgactcgtt tactaaacta aaagagtcaa ctcaaaaatt attcgatgcg cagaaaaaaa
      781 ggttaaataa tgaagataga atagaaacaa ctaaaaacaa tgtgattgcc aaacattgtc
      841 aaacagtcct ttcctttttg gttttgacta gcttttttgt gaaaaattgt gtaaaataga
      901 atagataaac gaggggaaac ctcggaaaat ttaaaggaga atccatctaa tggtaaaatt
      961 ggtttttgct cgccacggtg agtctgaatg gaacaaagct aaccttttca ctggttgggc
     1021 tgatgttgat ttgtctgaaa aaggtacaca acaagcgatt gacgctggta aattgatcaa
     1081 agaagctggt atcaaatttg accaagctta cacttcagta ttgaaacgtg ctatcaaaac
     1141 aactaacttg gctcttgaag cttctgacca attgtgggtt ccagttgaaa aatcatggcg
     1201 cttgaacgaa cgtcactacg gtggtttgac tggtaaaaat aaagctgaag ctgctgaaca
     1261 atttggtgat gagcaagttc acatctggcg tcgttcatac gatgtattgc ctccaaatat
     1321 ggaccgtgat gatgagcact cagctcacac agaccgtcgt tatgcttcac ttgacgactc
     1381 agtaatccca gatgctgaaa acttgaaagt gactttggaa cgtgctcttc cattctggga
     1441 agataaaatc gctccagctc ttaaagatgg taaaaacgta ttcgtaggag ctcacggtaa
     1501 ctcaatccgt gcccttgtaa aacacatcaa aggtttgtca gatgacgaga tcatggacgt
     1561 ggaaatccct aacttcccac cattggtatt cgaattcgac gaaaaattga acgtcgtttc
     1621 tgaatactac cttggaaaat aaaaaattgt aagtctagaa ttgatttcta ggctttttat
     1681 gttagtatgg aagtatgata aggaataaaa aacaagatta tgtactggcc tacaagcaac
     1741 cagtttcaac cacttacatg ggttgggaag aagaagcttt accgataggc aatggttctt
     1801 taggagcaaa agtatttggc cttatagggg ctgaacggat tcaatttaat gaaaaaagtc
     1861 tctggtctgg aggtccactt cctgatagtt cagattatca gggtggaaat cttcaggatc
     1921 agtatgtttt tttagctgag attcggcagg ctttggagaa gagagattac aatctggcta
     1981 aggaactggc tgagcagcac ctaattgggc caaaaacgag tcaatatggg acctatctgt
     2041 cttttgggga tattcacatt gagttcagcc agcaaggtac gactttgtct caggtgacgg
     2101 actatcagag acagctgaat attagtaagg cacttgtgac gacttcttat gtctataagg
     2161 gaacgcgatt tgaacgtgaa gcttttgcga gttttccaga tgatctcttg gttcagcgtt
     2221 ttactaagga aggggcggaa actctagatt ttactataga actatccttg acctgtgatt
     2281 tggcttctga tggaaagtat gagcaggaaa aatctgatta caaggagtgt aagttggata
     2341 ttactgattc tcatatcttg atgaagggaa gagttaagga taatgatctg cggtttgcta
     2401 gttatctagc ttgggaaacg gatggagata ttagagtttg gtcagatagg gttcagatat
     2461 caggagccag ttatgccaat ctcttcttgg ccgctaagac ggattttgcc caaaatcctg
     2521 ctagcaatta tcgcaagaaa ctagatttag agcaacaggt gatagacttg gtggacacag
     2581 ctaaagaaaa gggctatacc caattgaaat caaggcatat cgaggactac caagccttat
     2641 tccagcgtgt tcaattggat ttggaagcta atgttgacgc attcactaca gatgatttgt
     2701 taaaaaatta taagccacaa gaagggcagg ctttggagga gctgttcttc cagtatggac
     2761 ggtatttatt gattagttcg tccagagact gcccagatgc tctaccagct aacctacagg
     2821 gagtctggaa tgcggtcgac aatcctcctt ggaattcgga ctatcactta aatgtcaatc
     2881 tgcagatgaa ttattggcca gcctatgtta ccaatctcct agaggcggtc tttccggtca
     2941 tcaactatgt agatgatttg cgtgtctatg gtcgtctagc ggctgtaaag tatgcaggaa
     3001 tcgtctctca aaaaggtgag gaaaatggtt ggttggttca tactcaagcg actccctttg
     3061 gttggacggc acctggttgg gattactatt ggggttggtc accagctgcc aatgcgtgga
     3121 tgatgcaaac tgtttatgaa gcctattcat tttataggga ccaagactat ctcagggaga
     3181 aaatttatcc catgttgagg gaaacggttc gtttttggaa tgccttttta cataaggatc
     3241 agcaggcgca gcgttgggtg tcttctccgt cttattcccc agaacatggg ccgatttcga
     3301 ttggcaatac ttatgaccaa tctctgattt ggcagttatt tcatgatttt attcaggctg
     3361 ctcaggaatt gggactggat gaggacttgt tgactgaggt taaggagaag tctgatttac
     3421 taaatccttt gcaaatcact caatctggtc gaatcaggga gtggtatgag gaggaagagc
     3481 agtattttca aaatgagaaa gtggaggccc agcatcggca cgcttcccat ctagtgggac
     3541 tctatcctgg caatctcttt agctacaagg gacaagagta tattgaagcg gcacgtgcta
     3601 gcctcaatga tcgtggagat ggcggcacag gctggtccaa ggctaataag atcaatctct
     3661 gggcgcgttt gggagatggc aatcgagccc ataaattatt ggcagagcag ttaaaaacat
     3721 ccaccttgcc aaatctttgg tgtagccatc ctccttttca gatagatggt aattttggtg
     3781 ctactagtgg catggcagaa atgttactcc agtctcatgc agcttatctg gtacctctag
     3841 ctgccctacc tgatgcttgg tcaacaggtt ctgtttcagg cttaatggca cgtggacatt
     3901 ttgaagtgag catgagctgg gaagataaaa aactcttaca gttgaccatt ttatcaagga
     3961 gtggaggaga tttgcgagtt tcttatccag atattgagaa gagtgtgatt aaaatgaatc
     4021 aagaaaaaat aaaagcgaaa tgcatgggga aagattgtat ttcggtggca acagcagaag
     4081 gtgatcttgt tcaattttat ttttaagaag atgttataag gcagtaattt gaaacttcct
     4141 tttaataagg atttaagaat ataggcagtt tccaactagt tgaaaaagcg ttataatgat
     4201 aataggaagt aatactcaat gaaaatcaaa gagcacaaac taggaagcta gccgcaggtt
     4261 gctcaaaaca gtgttttgag gttgtagatg gaagctgacg tggtttgaag agagattttc
     4321 gaggagtata atttgtttga tagagggtgg gtctgatggc ttatattgag atgaaacact
     4381 gttacaagcg ttatcaggtt ggggacacgg agattgtggc caatcgtgat gtgaattttg
     4441 agattgaaaa gggggagctg gttattatcc ttggtgcttc aggtgcaggc aagtcaacag
     4501 ttcttaacct tcttggggga atggatacca atgatgaagg ggaaatctgg attgatggtg
     4561 ttaatattgc ggattatagt tcccaccagc gcaccaatta ccgtagaaat gatgtggggt
     4621 ttgtttttca gttttataat ctagtttcta atctgacagc taaggaaaat gtggaactgg
     4681 cttctgaaat tgtgacagat gccttgaatc ctgatcaggt cttgacagat gtaggtctgg
     4741 ctcatcgtct caataacttt ccagcccagc tttctggagg ggagcaacag cgagtctcca
     4801 ttgcacgcgc ggtagccaaa aatcctaaaa ttctcctttg tgatgaaccg actggagcct
     4861 tggattatca gacgggcaag caggttttga aaattctcca agacatgtct cgtcaaaagg
     4921 gagcgacggt gatcatcgtg actcataatg gagctttggc gcccattgct gatcgcgtga
     4981 ttcatatgca cgatgccagt gtcaaggatg tggtgctcaa ccagcatcct caggatattg
     5041 acagtttgga gtactagcat gatcaagcga aaaacttatt ggaaggactt aattcagtcc
     5101 ttcacagact ccaaggggcg ttttttatcc atcttgatcc tgatgatgtt gggatctcta
     5161 gccttagtag gcctcaaagt aaccagtccc aacatggagg cgacagctaa tgcttattta
     5221 acaactgctc aaaccttgga tttggcagtc atgtctaact atggcttgga tcaagcagac
     5281 caagaagaac taaaacagac ggagggcgca gaggtcgagt ttggctattt gacagatgtg
     5341 actatggata atgggcagga tgccattcga ctgtactcca aaccagagcg aatttcaacc
     5401 tttcagctaa gaaagggacg acttcctcag tcagacaggg aaatcgcttt ggccactcat
     5461 ttgcaaggcc aatacagcgt gggacaggag attagtttta aagaaaaaga agagggtcat
     5521 tcctctttaa aagaccatac ttataccatt actggttttg tggattcggc tgaaatcctc
     5581 tcccagcgag atatgggcta cgcaggaagt ggaagtggga ctctgacagc ctatggggtg
     5641 attttaccta gtcaatttga tcagaaagtc tacaatatag ctcgtttgaa atatcaagat
     5701 ttagcaggtt taaatgcctt ttcatcagct tatgaagaaa aatccaagca acatcaggaa
     5761 gaccttgaac aaactttatc agataatggc aaggtacgtc tgcaactttt gaaaaaagaa
     5821 ggacaagagt ctctagacaa ggggcaagag actcttgaca aggctcagac taatttgcag
     5881 gaaggcaagc gtcgtttagc agctgctcaa gctcgtatac aggctcaaga aagtcaacta
     5941 gccttgtttc ctcaagctca gagagagcag gctagtgctc aacttaccca agccaagcag
     6001 gaactgggca aggaagagga caaactaaag caagctgaac aaaatctagc ccaagaaaag
     6061 gaaaaattag aaaaacatca gcaagtcttg gatgatttgg cggagccaag gtatcaggtt
     6121 tataatcgtc agaccatgcc aggtggtcag ggctatctta tgtatagcaa tgcttcatcc
     6181 agtattcgag cagtgggcaa tatctttcct gtggtacttt atgccgtagc agccatggtg
     6241 acctttacga ccatgactcg ctttgtagac gaagagcgaa ctcatgcagg gatttttaag
     6301 gccttgggtt atcgtagtaa ggatattatc gccaagtttc tcctttatgg actagtagct
     6361 gggactgtcg gaacggctct aggtagtata cttggtcatt atttgctagc cagtgtaatt
     6421 tcaagtgtca ttacaaaagg catggtggtg ggagaaaccc agattcagtt ctattggacc
     6481 tatagcttac tagctcttgt cttgagctgg ttggcgagtg tgttaccagc ctatctggtg
     6541 gcttggaggg aacttcatga cgaagcagcc cagcttctac ttcctaaacc tcctgtcaaa
     6601 ggagctaaaa tcttattgga gcgtatcggt tttatctggc gtcgtctcag ttttactcat
     6661 aaggtaacag cccgcaacat ctttcgttat aagcagagaa tgttgatgac aatctttggt
     6721 gtggcaggtt ctgtagctct gctctttgca ggtttgggaa tccaatcttc tgtagcagga
     6781 gttccgtcta aacagtttca acaaatccaa cagtatcaga tgcttgtctc tgaaaatcct
     6841 agtgcgacca atcaggacaa ggtagagcta gcagaagtgt tgaaagggca ggagatacta
     6901 gcctaccaga aaatctattc taaaacgcta gacaaggatt tcaagggcag ggctggtctt
     6961 caaaacatta ctcttatgat gatagagaag gaagatttga ctccctttat ccatcttcaa
     7021 catcatcagc aggagctgac attaaaagat ggcatcgtta ttacagctaa actcgcccag
     7081 ctggcaggtg tcaaggttgg gcagacttta gaaattgaag gtaaggaact aaaggtcgct
     7141 gctattactg agaactacgt tggtcacttt atttatatga gtcaggctag ctatgagcaa
     7201 ctttacggac agctacccca agccaacact tatctggtct cattaaggga taccagtgca
     7261 actagtatcg aaagtcaggc gggcttgctt atgaatcaat ctgcggtgtc cagtgttgtc
     7321 caaaatgctt cagccattcg actcttcgac tctatcgcta gctcactcaa tcagaccatg
     7381 accatcttgg tcatcgtatc ggttctatta gctattgtca tcctttacaa tctgaccaat
     7441 atcaacgtag ctgagagaat ccgtgaactc tccactatca aggttctcgg ttttcataat
     7501 aatgaagtca ccctctacat ttaccgtgag acgattgtgc tgtcccttgt gggaatcgta
     7561 cttggtctgg tagctggttt ctatttacac caatttttga ttcaaatgat ttcgcctgcg
     7621 actattctct tttatccgca ggtaggctgg gaagtctatg taatcccagt ggcagcagta
     7681 agcatcattt tgaccttgct tggtttcttc gtcaattatt atctgagaaa ggttgacatg
     7741 ttagaagccc tgaaatctgt agagtaaggt agttattttt agctgattga acttctattt
     7801 actaatattc aaaaatcctc cgtttcaaag agcagggaac tctttgtgac agaggatttt
     7861 ttctataggg ctttagcagc tgcaattgcg gcttcgaagt ttggctcaga attgatatta
     7921 tccacgtatt caacgtagcg aatcgtattg tcagtatcga ggacaaagac tgcgcgtgct
     7981 aataggtgcc attcgttgat caagagggca taatcgcgtc cgaaagaatg gtcaaagtag
     8041 tctgaaagca taatggcatt gtcaaggcct tcagcaccgc accaacgttt ttgagcaaaa
     8101 ggtaggtcca ttgaaacagt caatacgacc gtgttgtcca gtccagccaa ttcttcatta
     8161 aaacgacgtg tttgagttga gcagatgcct gtatcgatag aaggaacgac actcaagact
     8221 tttttcttgc catcaaaatc agccagagat tttttagaaa gatctgttgt agtaagagaa
     8281 aaatcaagcg ccttgtcgcc gacttgtagt tgtttacctg taaagctcac aggatttccg
     8341 agaaaagtta ccataggata ctccaatctt ttttcttcca ttgtatctga aacagtcaga
     8401 attttccaat gatttgaccg gaaatgtgtg catagaaaaa acgccagctc acatgagaat
     8461 gacgtttttc agaggcttat tttgccaatc cttcagcaat cttgtcaagg ttgtatttca
     8521 tcatgctgta gtagctgtcg ccttctttac cttgttctgc gatagagtca gtaaagattt
     8581 gtgcgtagat tgggatgttt gtgtcttgag aaacagtttt cattggacgg tcatccacac
     8641 ttgattctac aaagagtgat ggaacttttg tttggcgaag tttttcaacc aaggtcttga
     8701 tttgttcagg agttccttct tcttcagtat tgatttccca gatgtaggca cttgggacac
     8761 cataggcttt agagaagtat ttgaatgctc cttcgctggt tacaatgagt ttcttttcag
     8821 cagggatctt attaaattta tccttacttt ctttatcaag tttgtctaac ttatcagtat
     8881 attctttgag atttttttca tagaattctt tattgttagg gtctttggcg ctcaattgtt
     8941 tggcgatatt tttagcaaaa ataataccgt tttcaaggtt aagccaagcg tgtgggtctt
     9001 cttttccttt ttcattttga ccttcaaggt agataacatc aacgccgtcg ctgactgcga
     9061 agtagtcttt gttttcagtt ttcttggcat tttctaccaa ttttgtaaac caagcattgc
     9121 cacctgtttc aaggttgata ccgttataga aaatcaaatc agcctcagaa gttttcttaa
     9181 cgtcttcagg aagtggttcg tattcgtgtg ggtcttgccc aatcggaacg atactatgaa
     9241 ggtcaatttt gtcaccagca atatttttag taatatcagc gatgattgag tttgtagcaa
     9301 caacttttag tttttgacca gaagttgtat ctttttttcc gctagcacat gctacaagaa
     9361 tgattgcaga aagaaagaga acgagtaatg tacctaattt tttcattaga tcctccaatt
     9421 tattagggct ttgcccctta ttttaacaaa tgtttatttt tcagtttcaa atatcgttgt
     9481 ttgggagcga taaagaagct aatgagaaag aaactagcag ctgtaagcac gatactagaa
     9541 cctgccgcaa cattaaaact atagccaata aagagtccca aaactgaagc agtagctccg
     9601 aaggttgagg aaaggaaaat catgcttttc agactattag catacagata agcagttgca
     9661 gctggggtaa tcagcatggc tacaatcagg atagttccga cactttgcat ggctgtcaca
     9721 gacacgagag tcaggagtac catgagaagg tagtgataga aattgacagg cattcccatg
     9781 gctttagcca agagttcatc aaaggaagtt atcaagagtt gcttgaagaa aatccagatt
     9841 aacaagagga tggctgcccc cacacccata gtaataaaca tatccgtatc ttggacggcc
     9901 agaatattac caaaaaggat atggaaaagg tcagttgaac ttttagcgac accaatcaag
     9961 atgataccga gggctaagaa agaagaaaag gtaatgccga tggcggtatc gcttttgata
    10021 atcgagtttc ctttgatgta ggtaatgatg atggcagcta gcaatccaaa gacaatggct
    10081 ccgataaaga agtcaaggcc caagatgaag gagagggcta cacctggtaa gacagcatgt
    10141 gaaatggcat ctcccatgag tgacatcccg cgtagaataa tgaaacatcc cacggctcca
    10201 gctacaatcc cgacgacaat agctgttatc aaggcatttt gtaggaaatg gaatttttgc
    10261 aatccatcga taaattctgc aatcataggt cacctccatt gaaaaagagt tgattaccgt
    10321 aagcttcttt tagattggtt tcggtaaaag tttcttttgt tggaccaaag gcaatcactt
    10381 ctcgattgac aagtaagact tgatcgaagt agtggggaat cttgctgagg tcgtggtgaa
    10441 cgatgagaac cgtcttccca gcttttttca aatctctcag cgtattcatg atgatttcct
    10501 cactgacaga gtcaatccca gcaaagggtt catccaagag gatatagtcg gcttcctgca
    10561 ccaaacatct ggcaatcaag acccgctgga attgacctcc agacagttga ctaatttgac
    10621 gttcagcgta gtcagctagg ccgacgattt caagggcctc ttgcactttc ttccaatgtt
    10681 tagcctttaa acttcgaaag agaggaatag agggaaatag tcctaacgag acgcattcct
    10741 tgaccttgat gggaaagttg tagtcgatat tgattttttg ttcgacatag gcaattcggt
    10801 gtaaggattt tttaacttcc ttgtcatcga gaaatgcctg accttgatgt gggataattc
    10861 ccagcatacc ttttaatagt gttgatttcc cagcgccgtt tggaccaatg atgccggtaa
    10921 ttgttggtcc atggagcact agtgaaatat ccttaagtgc caacgtttct ttgtaggaga
    10981 cactgaggtt ttcgatacgt atcataaact tgtattcctc ctgtctctta atatacatta
    11041 aaaaaaaaat taagtcaagt taatttttga aaaaattaaa ataataactg aaaaatagat
    11101 tctaaagata actttcagga taaatttcta aattataaaa cgcatagtat caagtgtaaa
    11161 aaacttggaa ttatgcgttt tatcatggaa agatttttta taatagctaa aaaataatag
    11221 ttaaatggtt attaattgca ttccctagtg atttttgtta agataaatgc aaatacaaat
    11281 gaaagcgaga acaagatgac acgttatcaa gatgattttt atgatgctat caatggagaa
    11341 tggcaacaga cagctgaaat cccagcagat aagtctcaaa caggaggttt tgttgattta
    11401 gaccaggaaa ttgaagacct gatgctggcg acaacagaca agtggttagc aggtgaagaa
    11461 gtgcctgagg atgctatctt ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt
    11521 gacaagagag aagctgacgg tatcacacct gtcttaccac tccttaaaga attccaagaa
    11581 ttggaaactt ttgcggattt tacagctaaa ctagcagagt ttgagcttgc aggaaaacca
    11641 aacttccttc cttttggtgt atcgccagac tttatggatg ctagaatcaa tgttctatgg
    11701 gctagcgctc caagcacaat cttgccagat acgacctact atgcagaaga acatcctcag
    11761 cgcgaagagc tcttgactct ttggaaagaa agcagcgcaa atctcctcaa ggcttatgat
    11821 ttctctgatg aagaaattga agacttgcta gaaaaaagac ttgaattgga ccgccgagtt
    11881 gcggcagtgg tgctctctaa tgaagaaagt tcagaatatg ctaaactcta tcatccatat
    11941 tcttacgaag atttcaagaa attcgcgcct gccctacctt tggatgactt cttcaaagca
    12001 gttattgggc aattaccaga caaggttatt gtagacgagg aacgtttctg gcaagcagca
    12061 gagcaatttt acagtgagga agcctggtct ctccttaaag caaccttgat tttgagtgtt
    12121 gtcaatcttt caaccagcta tttaacagag gatatccgtg ttttgtctgg tgcctacagc
    12181 cgtgcccttt ctggagttcc agaggcaaaa gataaggtca aagcagctta tcatctagca
    12241 caggaacctt tcaagcaagc cctggggctt tggtacgccc gtgagaagtt ctctccagaa
    12301 gccaaggcgg atgtggagaa aaaagtggca accatgattg atgtctataa ggagcgtctg
    12361 cttaagaatg actggctcac tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg
    12421 atcaaacctt atattggcta tccagaagaa ttgcctgcac gttacaagga taaggtagtg
    12481 aatgaaactg ccagtctttt tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac
    12541 agttggagta agtggaacca gcctgtagac tataaggaat ggggcatgcc tgctcatatg
    12601 gtcaatgcct actacaatcc tcagaagaac ctgattgtct ttccagcggc cattttacag
    12661 gcgcctttct atgacttgca tcagtcatct tctgctaact acggtggtat tggggcagtg
    12721 attgcccatg aaatttccca cgcctttgat actaacgggg cttcctttga cgaaaatggt
    12781 agcctcaagg attggtggac agagagcgac tatgctgcct tcaaggagaa aacacaaaaa
    12841 gtcattgacc aatttgatgg acaggattct tatggagcaa ccattaacgg taaattgact
    12901 gtatcagaaa acgtggctga cttgggagga atcgcagcag cgcttgaagc agctaagaga
    12961 gaagcagact tctcagcaga agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa
    13021 ggtcgaccag aatttatgaa acttttggct agcgtcgatg tgcacgcacc agccaaactc
    13081 cgtgtcaatg tgcaagtacc aaacttcgac gatttcttta caacctatga tgtcaaagaa
    13141 ggagacggaa tgtggcgttc accagaggag cgcgtgatta tttggtaata caaaaaatct
    13201 agtcatcaga aaaaaggcat ccaatcacgt gtgaaaacct tgataggatg ccttttgtaa
    13261 tagaaagatt tgctggatag tttacttaaa tttcgattgt catcatcttg ctagaaaaag
    13321 ggattgaagg ccttttcgtg agcgatagta gtagctggac catgtcctgg atagacatcg
    13381 tagtttggta gggtgaagag ttgggtctgg atactatgaa ggagttgctc catgctacca
    13441 gtcggaaggt cggtccgtcc gatagtttcg cggaatagag catctcccgt caagactagg
    13501 tgagcatcag gaaagactag ggaaacacca ccgatagagt gccctggggt cggtagaacc
    13561 ttaaaacgaa attcctctag ttggtattct tcgtgaaaga caaaggtgtg ttctgcaggt
    13621 tttgtgacca catctgccat atcatcgtgg cgagggagac cggagagatt atcgacagga
    13681 gtgtagagcc agctggcttc gctctctgcg atatagacag gaggattgcc aaacgtctcg
    13741 cgaaccaagt ccagactcat gatatggtca taatgggcgt gggtcaagag aatagcacag
    13801 atcggtttgt tgatcttctc gattgtctga cgaatggctt cccaatgact accaggatcg
    13861 acgacgatga ggtgcttttc gccttctaga taataggtat tttcataggc aacaggattc
    13921 acggttttat ggattttcat actagctcca atctcaaaga atgtactaat actcttcgaa
    13981 aatctcttca aactgcgtca actttatctg caacctcaaa gcagtgcttt gaacagcctg
    14041 cggctagctt tctagtttgc tctttgattt tcattgagta taaattaagt atagcacagt
    14101 tagggagaat aggtaaggat ttaaaatgaa cttaaaaacc agcatgacta gatgaagaca
    14161 ggctggttat caatttatca atattggaaa ggtgtcaatt gcccttcata ggttgcataa
    14221 actccgtcat tagcttgttt gatagacgtg atgtttagag tgctaccgta gttggcttct
    14281 cgtttgtcgc tatattcact ataagttatc ctactgggca ggttctggtc gttagcatag
    14341 tattgaacga ctgtttttta tagctttgct ggctgaatag gaacaggcag caaactccta
    14401 acattaggag agcaaagata gaaatagcag tttttttcat aggtattctc cttataaact
    14461 aaaggataga agaaagtatc ttgaggattt ttatactctt cgaaaatctc ttcaaaccgc
    14521 gtcaacgtcg ccttgccgta tatatgtgac tgactttgtc agtcttatct acaacctcaa
    14581 agcagtgctt tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt
    14641 attaattcca aaatccagtc aaggtaccag tgtatgtgat acgagttcca ccgtttatct
    14701 ttcgtatctt caatggaatt ggggaaatca gaaagtcttt gggttacaat atggtttccg
    14761 ttcttctatc tctccttcta tcacctaagt ttaaaatcta acttcgtagt atattatggg
    14821 ccgataattc agaattatca agcaattttg aattattttt ttcttattct gttccaatct
    14881 agttttcata ttcttaaaaa agtgataaaa tggtaggaag aattggagag tagagatgcc
    14941 gaaagaagtg aatttaacag gcgaagaagt tgtcgcttta accaaagaat atttaacgga
    15001 agaggatgtt cattttgtcc ataaggcctt ggtctatgct gttgaatgcc acagtggtca
    15061 atatcgcaaa tcaggcgagc cttatatcat tcaccctatc caagtggcag gtattttagc
    15121 taagctaaag ctggatgctg taacagtagc ttgtggattc ttgcatgatg tggtggaaga
    15181 tacagatgcg accttggacg atttggaaag agagtttggt cctgatgtgc gggtgattgt
    15241 tgacggagtt accaagcttg gcaaggtcga gtacaaatca atcgaggagc aattagcgga
    15301 aaatcatcgc aagatgctca tggccatgtc tgaggacatc cgcgttattt tggtcaaact
    15361 gtctgaccgc ttgcacaata tgcggaccct gaaacatctt cgaaaagaca agcaggagcg
    15421 tatttccaaa gaaaccatgg aaatctatgc cccacttgcc catcgtttgg ggatttccag
    15481 tgtcaaatgg gaattagaag acttgtcttt ccgttatctc aatccaacgg agttttacaa
    15541 gattacccat atgatgaagg aaaagcgcag ggagcgtgag gccttggtgg atgaggtagt
    15601 cacaaaatta gaggagtata cgacagaacg tcacttgaaa gggaagattt atggtcgtcc
    15661 caagcatatt tactcaattt tccgcaaaat gcaggacaag agaaaacggt ttgaggaaat
    15721 ctatgatctg attgctattc gttgtatttt agatacccaa agtgatgttt atgccatgct
    15781 tggttacgtg catgaatttt ggaaaccgat gccaggtcgc ttcaaagact atattgccaa
    15841 ccgcaaggcc aatggttatc agtctatcca tacgactgtt tatgggccaa aagggccgat
    15901 tgaattccag attcgaacca aggaaatgca cgaggtggct gagtacgggg ttgcggctca
    15961 ctgggcttat aagaaaggta taaaggggca agttaacagc aaggaatcag ctattggaat
    16021 gaactggatc aaggagatga tggagctcca agaccaggct gatgatgcta aggaatttgt
    16081 ggactctgtt aaggaaaact atctggctga ggagatttac gtttttaccc cagatggagc
    16141 tgtccgttcc cttcccaaag attcaggacc gattgatttt gcctacgaaa tccataccaa
    16201 ggtcggtgaa aaagcaactg gtgccaaggt caatggccgc atggttccac tgacaaccaa
    16261 gttaaagaca ggggatcagg ttgaaattat cgccaacccg aactcctttg gacctagccg
    16321 tgactggctc aatatggtca agactagcaa ggcgcgcaat aagattcgcc agttctttaa
    16381 aaaccaagat aaggaattgt ctgtcaacaa gggtcgtgag atgctgatgg ctcagttcca
    16441 agaaaatggc tatgtggcaa ataaatttat ggacaagcgc cacatggatc aagttctgca
    16501 aaagaccagt tacaagacag aagactccct ctttgcggcc attggttttg gggaaatcgg
    16561 tgcgattacc gtctttaacc gtctgactga aaaggaacgc cgtgaggaag agcgtgccaa
    16621 ggccaaggct gaggcagagg agcttgtcaa aggtggcgag gtcaaggttg aaaataaaga
    16681 aactctcaag gtcaagcatg aggggggagt ggttattgaa ggtgcttctg gtctcctagt
    16741 gcggattgct aagtgttgta accccgtgcc tggtgacgat attgttggct acattaccaa
    16801 gggtcgtggt gtggctattc accgtgtgga ctgtatgaac ctgcgtgccc aagaaaacta
    16861 cgagcaacgt ctccttgatg tggaatggga agaccagtac tctagctcaa ataaggagta
    16921 tatggcccat atcgatatct acggtctcaa ccgtacagga ctgttgaacg atgtactgca
    16981 agttctttca aatacaacca agaatatttc aacggtcaat gcccaaccaa ccaaggatat
    17041 gaagtttgct aatatccatg tgtccttcgg tattgccaac ctctctacac tgaccacggt
    17101 tgtcgataaa attaagagtg tgccagaagt ttactctgtc aaacggacca acggctagtt
    17161 gtcctagctc ttactagaaa ggctattatg aaaatcatta tccaacgggt taaaaaagcc
    17221 caagtgagta tagaaggcca gattcaggga aaaatcaatc agggactttt attgctagtt
    17281 ggtgttggac cagaggacca agaggaagat ttggactatg ctgtgagaaa actggtcaat
    17341 atgcggattt tttcagacgc agaaggcaag atgaacctgt ctgtcaaaga tattgaagga
    17401 gaaatcctct ctatttctca gtttaccctc tttgcggata ctaagagagg caatcgtcca
    17461 gcctttacag gggcagctaa acctgatatg gcatcagact tctatgatgc tttcaatcaa
    17521 aaattagcgc aagaagtgcc cgttcagaca ggtatctttg gagcagatat gcaggttgag
    17581 ctggttaata acggacctgt taccattatc ctagatacta aaaagagata agaaagacca
    17641 agcccagtcg gcttggtctt tctcatctat cataaaatac tccaaaaaga aatcggttct
    17701 tgatatgctt gggggaagtc tcttttcagg ctttggcaga tgcgatagga agggatgaga
    17761 tgtcctagga tgaggagagt tccctgaagg aaaagtggaa tatcacttaa agacaccaag
    17821 gagagaatca tcaggctatc ccataggaga atttgtaaag caaaacgcca gaatctcggt
    17881 ctaatctggg aatagagttg actaaagtgg tcacaaagtt ggtttgaaag ataggtcaat
    17941 agcacaggat gaaagaaaat gagccaaccg ctataaatca aaatccagtc ccaagtaagc
    18001 ccccctttta aatgtcaaaa atgccagcat gattccatca atgacaagga gttgaatggt
    18061 tttgatgaag atgatttttt tcatgataaa acctcctttt ccttagagac actcccataa
    18121 agagatgtgt ttgtcgtaaa agtctggata gttttctctt aggtagtcag ctgtcatata
    18181 ataaaaagta gaatggcaag cagtgataat tgacataaga gatgaaaaac gctgagaact
    18241 aatgaaggct aagagaacaa aaaaatagaa aatcaatggt gagaacccct aaatagtaga
    18301 agcgaatctt tttattgatt tgaggataaa tctcagcgaa ttgatgtttg agtcggacga
    18361 tcaagagaaa tagcaggagt ccttgagcaa ggaagaaaat taaaccagag agcaagagcc
    18421 actcaaaaga tgtctcgagt ctaatgataa aaaatgcaaa tagtagcaaa tcaataactg
    18481 caattgctat aaaatggatt ctatagagtt ttttcatgac aagacctccc tcttttatct
    18541 aacttcattc tactctaaaa gaatgggagt tacaactaaa atgataaaaa tagcagaggg
    18601 gagattctct taagttgact agtattcttt atttgagttt ccttctatta tctaacttct
    18661 tcatcattcc agacaaataa agctccgatt gcattgagga tataaaagat gtatttaccg
    18721 atattggcga agtttccttg aataccagct tttgtcagct gaacgaaatt gtaaatcaac
    18781 caaaagcccc actgtccctc attgccaatg cattcaaagc attggcaatg agggacagtg
    18841 caaaggcaat agttgttacg taggcaagga gattcatctt gcccccatat ccgatatagt
    18901 tggtcacaaa ggcaaagagg aaggcgatga tggaaatgat gatggccgcc aattttacct
    18961 gtttttggct catttggttg ggtctgcctt cttgcgaagc tttccatttc tttatagcaa
    19021 aggtataaat gaggaaggtg acgggatagg taatgatggc cgccttattt ccaaggatat
    19081 aatcaatagc accggacaaa atggtattaa caataccaaa gtaatttccc catttgctta
    19141 atttccccgt gaaacgagtg gacaacatgg aaatcccaac gttggttacg gaaatcaatc
    19201 caaagggtac aagagctgtc catagtcccc agtctacaaa tttatcgagg cgtgagttga
    19261 gataaccaga tgcaatcgca atcccaacga ccaaagcaac cccgaagagg tcaaatcatt
    19321 tagatgtagc aaaaattttt agtgattttt tcataggtta aactaccttt ctttttttca
    19381 aatactctac caccaaatga aagtaaaatc aaatgataga aataaaaccc tgaaaataaa
    19441 actttcaggg ttggtagggg acttgagaaa ttagttgatt ttctcgacat agagttgttt
    19501 tgcaatgtcc atattcactt gtaaatcctc gtcgttactg aggatagtga aggtattgct
    19561 gaagccatca aactgcttga cttggagctg gtcaccgatg tgaagtgagt gcttgtccag
    19621 ataatggaga atgtcaaaac tatcgtgcac ccgagtcagg cggtaggcgc cagcttcctt
    19681 gatatcagct agtgggaggt tattgatttc aacgaggagt tctcccttgg caggaatagt
    19741 tcctccgtgg gggcaggttt tagggaaacc tagcagttta tctagtcttt ccacgaacag
    19801 gtcagagaca gtgtgttcca agacctcagc ttcctcgtga atctggtcac ttgtatagtc
    19861 taaatgatga actagaaaaa cttcaatcaa gcggtgctta cgatagagct cagagaccag
    19921 tttgagaccg aggtcagtca gtagatagcc acattccttg tcctttagga tgagattttc
    19981 acttttcatt cgtttgatca tttcagttac ggcaggggga gagacttgca tgcgagccgc
    20041 aatttccttg ttggtaatct tatgcaggtc tatgccaatt tcataaatac attttagata
    20101 gtcttctttg tttggggtca ttcgtttcct cttgtctaat atctttatct agtatatcaa
    20161 aaaaagctag atttctctag ctgtgacttt ttatgttata cttattgcaa gagaaaaaac
    20221 gaggagatgg atatgacgaa aatagctctt ctttcagata ttcatggaaa taccaccgcc
    20281 ttggaggctg ttttggcaga tgctcagcag ataggagtgg atgaatactg gcttttggga
    20341 gatattctca tgccagggac aggacgtaga aggattttgg acttgttgga tcaactaccg
    20401 attacggcta gagttttggg aaactgggaa gacagtcttt ggcatggtgt ccgtaaggaa
    20461 ttggacagta ctcgccccag tcaacgctat ctcttgcgcc agtgccagta tgttttagag
    20521 gaaatttccc tagaagaaat tgaagtgctc cacaatcaac ctcttcaaat tcatcgtcag
    20581 tttggggatt tgacggtggg aattagccat catctgcctg ataagaactg ggggcgagag
    20641 ttgattcata ctggcaaaca agaggagttt gaccgcttgg tgactcatcc tccctgtgat
    20701 attgctgttt atggacatat tcaccagcag ttgcttcgtt acgggactgg tgggcaattg
    20761 attgtcaatc cgggttcgat tggccaacct ttctttttgg acgctcagct acggaaggac
    20821 ttgcgggccc agtatatgat tttggagttt gatgacaaag gcctggtaga tatggacttc
    20881 cgacgggtag actacgatgt ggcagcggaa ttgcagctgg ctaaagacct gagacttccc
    20941 tattttgagg tttactatga aagtctggtc aatgggatcc accatactca tcatcaggaa
    21001 tttttgagag aattggctca gaaagagggc tgcgatcggg agttagacga ctggttgaaa
    21061 agtggtaacg attgacatta caactaaaaa gggtataata atagaaaaag aagagtagag
    21121 gcagggtagc ctcgtaaaaa ggagaagagg atgcaaattc caagtagatt taccattgcg
    21181 actcatatgc tgataatcat tgccctcgag gggaaggaaa gcaaggtgac cagtgatttt
    21241 ctggctgcta gtgtcggggt caatcctgtc attatcagaa agatcttgtc ccagttgaag
    21301 aaggcagagc tgatttcagt agcgcgtgga acgggcggaa cagagattgt caaggacctt
    21361 aaggatatta gtcttttaga tgtttatcag gcggtcgaat gtcttggtaa gacaggtcaa
    21421 ctcttcagtt tccatgacaa tccgaatcca aattgccctg taggagctca tattcatgat
    21481 gttttggatc aaaaattgga gagaattcag ttgactatgg aggcagaact tggtcaaacc
    21541 agtctagaaa aagtcgtggc cgatgcagag agtcagatga aggattaaga gggataaatg
    21601 ccctcttttt tctttggata attatgataa aatgtagcta ttaaaggagt aagaaatgta
    21661 tctcgttata ggaattgtat tagcctttat agtgtcattt tggaaggata atagaagttt
    21721 gtggaatcca gtattatttt tattatccct catttcaagt tatttttatc tatcctacct
    21781 tttttataaa aatggatacg agaatgttca gttagctttt tatgtatttg cctttgtctt
    21841 acttcctttt ttgctttttc taagtggcat ctttttaatc tataatgggg tcattttgtt
    21901 gaagcgagag ggacgttcca agccccatta tctctcaatg ctctttgatt tttattgact
    21961 attagattct atttaaaaag acttagaatg cacatgaaag tatgtattct aggtcttttg
    22021 ttttgtatac atttaatttt caagagtatt atctattttt ccatgcctgg taacgagtat
    22081 caatcaataa ctgggtaagg cgacccaagg tttctctttc ttctggagtg agggattgag
    22141 cttggacaaa gagatgatga atgtattcaa gcgcctttaa ggaagccaag tcattgatag
    22201 agctaatacc agcctcaaga atagtgccaa agaagaggtc gaagtagagc tgaagttctt
    22261 cgtcagggac tgtggccacc cattctttaa aggttgtgtc tacttgctgg ctatcactgt
    22321 tggtcttatc cagttggacg aagtgcttgt cctcaatctg ccaactaaag gtatcgtgct
    22381 gggcgatgcc acccagggca gtactctgaa cgatgatttg gtgagcagga atttccagca
    22441 tcataccgat aatggaacct tgtggaatga atatcttgct tctatccatt atcctttgat
    22501 aacccgcagt ctgtgtcaat tcttgatgga gaccaggtgc atcaaatgta taaactgctg
    22561 tgatctgatt ttgcaaactt tgctcaattt ggctagcagc atagatagcg agatttcctc
    22621 ccttggaatg cccagctaga ataacctttt gcttaggatg atgggcaaaa aagttcttta
    22681 aatagcgaag ggcgtgcttt tgagcaggaa tttccttcat ataggtcagg tggaaaactt
    22741 ccttccagcc aatgatactg tcatctgtcc cacgaaagac aatcagatag gtatcgaggc
    22801 tgacacgata agtcatagcc gcaaattgct tttgcagttc agggtcgatg tcgttgataa
    22861 aatgggagag tttgcaattt ttgaagcgct tgtgttgagc caattcatct aataattgaa
    22921 ggcgattttt gctagtaagc atggtgggat ctcttggaac ctgaggtgct agatctaaaa
    22981 gacgttgagg aagtgtggag accagattat caaaggagag gtaggtgatt tctattaagg
    23041 ttagaatgtc taactcattc aagggaaggt cgtaataaga atcatatgcg acatctttca
    23101 gatagtcaaa aatattggcc ataagagctc ctttcttttt atttatctta gcaaatttcc
    23161 ctcaaattag ctagtagcat tgcctgtttg tactggctaa aaacaggcta tttcaaattc
    23221 agtttcagac catctggcat ggaaaaatct gttataataa tagaaaagga gaagcgcatg
    23281 cacaagattt tattaataga agatgatcag gtcattcgtc aacaggtcgg gaaaatgctc
    23341 tctgaatggg gatttgaagt ggtcctggta gaagacttta tggaagtttt gagtctattt
    23401 gttcagtcgg aacctcatct ggtcctcatg gatattggtt tgcccttgtt taatggttat
    23461 cactggtgtc aggaaatccg caagatttcc aaggtaccta tcatgtttct ttcttcgaga
    23521 gaccaggcta tggatattgt catggcaatc aatatggggg cggatgactt tgtgaccaag
    23581 ccttttgacc agcaggttct tttagctaag gttcagggct tgttgcgtcg ttcctatgag
    23641 tttgggcgtg atgagagttt gctggaatat gctggtgtta tcctcaatac caaatccatg
    23701 gatttacatt atcaagggca agtcttgaat ttgaccaaga atgaattcca gattttacgc
    23761 gtgttatttg agcatgcagg caacatcgta gcacgtgacg acctgatgcg ggaactttgg
    23821 aacagtgact ttttcattga tgataatacc ctctctgtca atgtggctcg tttgcgtaaa
    23881 aagttggagg agcagggatt ggtaggattt atcgagacca agaaaggaat agggtacgga
    23941 ttgaagcatg cttgattgga aacaattttt tctagcctat ctgcgctccc gtagtcgtct
    24001 ttttatctat ctgctttctt tggcatttct tgtcttactc tttcagtttt tatttgccag
    24061 tctaggaatt tacttcctct actttttctt cttgtgttgc tttgtaacca tcttattttt
    24121 cacttgggac atattggtgg aaacgcaggt ctatcgccag gaacttctct atggagagag
    24181 ggaagccaag tctcctttgg aaatagcttt agcagaaaaa ttagaagcgc gtgagatgga
    24241 actctatcag cagaggtcaa aagcagaaag aaaactgacg gatttgctgg attactatac
    24301 cttgtgggtc catcagataa agacccccat tgcagccagt caactcttag ttgcagaagt
    24361 ggtcgaccgc caactgaagc agcagctaga acaggaaatt ttcaaaatcg actcctatac
    24421 caacctagtt ttacagtacc tgcgtttaga aagtttccat gatgatttgg tcttaaagca
    24481 ggttcaaatt gaggacttgg tcaaggaaat aattcgtaaa tatgctcttt tctttattca
    24541 aaaaggctta aatgtcaatc tacatgacct tgataaagaa atcgtgacgg ataaaaagtg
    24601 gctgctagtg gttattgagc aaatcatctc aaacagtctc aagtacacca aggaaggtgg
    24661 tctggagatt tatatggatg accaagagct ttgtatcaaa gatacgggaa tcgggataaa
    24721 aaacagtgat gtcctccgag tatttgaacg tggcttttca ggatacaatg gccgtttgac
    24781 ccagcagtcc tctggacttg gcctttatct atctaagaaa atttctgaag aactggggca
    24841 ccagattcgt atcgagtctg aggtcggaaa aggaacgaca gtgcggattc agtttgctca
    24901 agtgaactta gtccttgagt aaaaatagat gagaaaaagc ctccagattg gaggctttta
    24961 tgctagactc ttatttctca acgcgtgatt tgttggcgat atcagctagg atagcttgaa
    25021 caaaattatc aactgagaca gtttgtgttt ctttttggcc gtagcgacga acgttgactg
    25081 tttcgtcttc catttctttg tctccaacaa ttaattggta aggaatcttg ctggtttgtg
    25141 aagcacggat cttgaactgc attttttcat tgcgctcatc tacgtctgca cggacaccgc
    25201 ggtcacggag tttcttggct acttcccaag cgtagtccac gtgtttttcg ttagatactg
    25261 ggataagggt tacttggtgt ggtgccagcc atgttgggaa ggcacccttg tagttctcaa
    25321 tcaagatagc tgtgaagcgt tccatagttg agataacccc acggtggatc atgactggac
    25381 ggtgatcttc gccatcagct ccgatgtatt tgaggtcgaa gcgttctggc aacaagaaat
    25441 caagttggat agtagaaagg gtttcttctt ttccaagggc agttttaatc tggatatcca
    25501 attttggtcc gtagaaggcc gcttcacctt cggcttcaaa gtagtccacg cccatttcat
    25561 caagagctgc acgaagcatg gtttgggcat tttcccacat ctcatcgtta tcaaagtact
    25621 tatgagtatc ttgagggtca cgaagagaga ggcggaagcg gtagtcagtc aagttgaagt
    25681 cttcataaac atcgataatc aactgaaggg cacgttggaa ttcttcttgg atttgttctg
    25741 gagtaacgaa taggtgaccg tcgttgagtg acatttcacg tacacgttga aggccagtga
    25801 gggcaccaga tttttcgtaa cggtgcatca taccgatttc agcgatacgg attggcaatt
    25861 cacggtaaga gtgaacatgg tgtttgaaaa cttggatgtg gtgcggacag ttcattggac
    25921 gaaggacaaa ttcttccccg tcacccatgt ccatggttgg gaacatgtct tcttggtaat
    25981 gatcccagtg gccagaagtc ttgtaaagct caacagaagc aagtggtgga gtgtagacgt
    26041 gttggtagcc agaagccaac tctttgttta cgatgtagcg ttccaattca cgacggatag
    26101 tcgcaccatt tggcaaccag aatggcaaac cttgtcccac ttcttgtgaa atcataaaga
    26161 ggtcaagctc tttaccaagt ttacggtggt cacgttcctt agcttcttca cgcatttgaa
    26221 ggtagttttt caagtctttc ttttcaaacc aagctgtacc gtagatacgt tgcatcatag
    26281 cgttgtcgct gtttccacgc cagtacgcac cagctacatg gagaaggtgg aagatttgga
    26341 tacgacctgt tgatggaacg tgaggtccac ggcagaggtc tacatattca ccctgacgat
    26401 agatagtcaa accgccttcg tcttctgagt gttcttcaat caattccaac ttgtaagggt
    26461 catttttgaa gatttcacgt gcctcgtctt tagtcacttc ttcacgaata gatgggaagt
    26521 tttctttgac gattttttgc atttcttctt cgatacgagg aaggtcttcg ttagagattt
    26581 gaccagctgt gttgtcagta tcgtagtaga aaccatcttc gatggctgga ccaactccca
    26641 agtgaatgtc tgggaaaaga cgacgagctg cttgggcgaa caagtgagct gctgagtggc
    26701 gcaagattgg aagggcatct tcgtgatcag gtgtcacaat ttcgatgctt ccatcttcag
    26761 tgatagcgcg agtagtgtcg atgagtttgc cgttgaattt accagccaag gcttttttag
    26821 ctagggaatt gctgatagat tgggcaattt caaaagttgt tacgccagat tcgaattcac
    26881 gaacagcgcc atctgggaaa gtaatgttaa tcatgatgtt ctcctttttt attatttcat
    26941 agtttctaag cattgatttt ttatcatcag actacttcca agtcctaacg ttcaattgct
    27001 tttctttatc agagaggaag ttttccattt ccgtcagaat gtctatatcc aaacgttgag
    27061 aaagttctaa tagccaccag atattttctg aaagtttttg ttccagtgtg tagggtgttt
    27121 catcatagta gcgtccttgc tttgtcatca ccagtcgttg gaaatttcca atatcattag
    27181 ataaagccaa ggggtcttct tctaccgtcc acttggaatc atgatgctta acttccagtt
    27241 cgtgataagc ttgtcggatt gcccaactgc gctccactaa ttcttgcaac tccataatta
    27301 gtatcctaat aaaaaaatgc gacatcctcg aaaggacgtc gcaacgtggt tccaccttca
    27361 tttatgtacc tcaaaagaga gggacacctc tgattggctc taacgtggcc accgttttat
    27421 gttttcataa aaaactcaag agtagtatca gtttagactt cctatgcgtt tccagcaacc
    27481 acgcactctc tagtagaaag ggactaagtg acttgtctct atggattatt atagcatgat
    27541 tgtgagattt ttcaaggatt ttgtgaaagt tttttgtttt tcattttttg tagaatatgc
    27601 ttgatgctaa taccagaatc catgcccacc agagcaactg tttcatagat tagcaagtaa
    27661 attagtataa actcaccaaa ggttatgata gtaaagtaaa agagcagtcc gttaccaact
    27721 aaccatcaaa gtgagaaacg gaaacggtag ctatagagta acgatacaat caagattacc
    27781 agaggtgtaa agaagagaag attgtttata tagagttcct tgagtgtaag ggggtcagaa
    27841 acaactagta agaacaactc ataaagtggc caataaaaga ataatatgac cagatagtag
    27901 gggagatggg aatagaatct acgcatgata atcacctcgt tttaaaaaaa cagacaactt
    27961 agatctcttg ctatgattat tatagcatgt ttaaaacaag aaagtaaatt tgttggcaaa
    28021 gaagattttt tttcactaga atcatggtta gttttcttgg tagaaatatt ttgataataa
    28081 ttaagcaaaa ctattgacat tgattattaa gagtgtcaca attgttgtaa ctaaaataat
    28141 tacaataaga gaggtataaa aaatgaaact agcagttatt gcagcaaatg gacaagcggg
    28201 gaaagcaatt gttgaagaag tagtcaaacg aggacatgaa gtaacggcta ttgttcgttc
    28261 tgaaaacaaa agtcaatctg agtctattat taaaaaagat ttatttgagt tgacaaaaga
    28321 tgatcttact ggatttgatg ctgttatttc agcgtttggt gcttatacac cagatacgct
    28381 accgctccac agcaaatcaa tcgaactatt taatcagctt cttgctggaa cacagacacg
    28441 ttttctagtt gtagggggag caggaagtct ttatatagat gaaacaaaaa cgacacgact
    28501 tttagatacg tctgattttc ctgaagaatt taagtcacta gcaaaagctc aagcggatga
    28561 attggatctt cttcgtacaa aaaataatct caactggact tttgtcagtc ctgctgtaga
    28621 ttttattccc gatggtgaaa aaacaggaaa ctacattcta gcaggagaaa tttttactac
    28681 taatgaaaaa ggaataagcc agattagtta tgcagattat gctattggat tggtagatga
    28741 acttgaaaaa ggtcatcata taaaagaacg tatctcttta cttgaaaaat aataactatg
    28801 agagtattaa tgtttgacag aaaatttaaa tcttggtaaa atagggattg tcgtaaagac
    28861 aaataacttc ttcttggtta caggcatgcc aacctgtcac tcggatgaag ccaaataaaa
    28921 aggagaaaca tcatggcaat ctcaaaagag aaaaaaaatg aaatcattgc acaatatgca
    28981 cgtcacgaag gtgatacagg ttcagtagag gttcaagttg ctgtccttac ttgggaaatc
    29041 aaccacctta acgaacacat caaacaacac aaaaaagacc acgctactta ccgtggattg
    29101 atgaaaaaaa tcggtcgccg tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac
    29161 cgttaccgtg agttgatcaa ctctctagga cttcgtcgct aattcaagat acaaaggccg
    29221 tcaaaaacac aaagcaaaaa taggaaaatt gacgaagaaa cttcagtttc taggagattt
    29281 tatctttttt gccaagtgct taggccgtgt tcaattgagc atatcttgat aataaagcta
    29341 ctctaaattg ggtagctttg ttgcgttgtc accttacctc gctatactca agtataatct
    29401 tcggttacgg ttcctagcac tgtaaggtaa aataaactag cttttctccc ttcggggaga
    29461 tttttttgtt tcactgaaag tttcgtacga tcttcacctc gtcccctagt ctataaacga
    29521 tttatctagc aagaatcatg atgctaaggg cgtcaaaaat ccgtatgaaa atagggaaat
    29581 gacacagtgt tcgatgagca caaggagttt catctttttc actaggattt tagcccgggc
    29641 taaaatcagc tctctgactt cagagggctt ttttattgag gttttatcgg taacaatttt
    29701 ggagactaca aaaacctcaa atggtatcag ctaattacac cataaaggtg cgcagttact
    29761 cggcttttca agccgagtag ctgtatgcaa gccccctaga agagcccact ctttacaaag
    29821 taaagtatag tatgttatac tttacatgga agtagtcact gaattccagt tagaaattac
    29881 tttgtaacta cgttttgagg aggagtaaaa tgctttccta cgttcgacat tacccactag
    29941 cgatagctaa attaatgtgt ctgtgctctc ctaaaatctg ctgatttatt actgactaat
    30001 acaggaggtt ttttttatgg gacagacaat catatctgct attggtgttt atatttccac
    30061 cagtatcgat tatttaatta ttttaattat tttatttgca cagctatcac agaataaaca
    30121 gaaatggcat atttatgcgg ggcaatatct aggcacaggc ttacttgtag gggcgagttt
    30181 agttgctgct tatgtcgtta atttcgtgcc tgaagaatgg atggttggat tgcttggttt
    30241 aatccctatc tatttaggga ttcgctttgc aattgttgga gaagatgcgg aagaagaaga
    30301 ggaagaaatt attgaaagat tagaacaaag caaggcaaat caactgtttt ggacagttac
    30361 attgctgaca attgcgtctg gcggagataa tttaggtatc tatatacctt attttgcttc
    30421 gttagattgg tcacagaccc tcgtggcctt gcttgtgttt gtaatcggca taattatctt
    30481 ttgcgagatt agtcgggtgt tatcctctat tccgttaata ttcgagacaa ttgaaaaata
    30541 cgagcgaatc attgtgccct tagtattcat tctacttgga ctatacatca tgtatgaaaa
    30601 tggcacgata gagacttttc tgatcgtgta gatttttttg tttcactagg attttagccc
    30661 gagctcaaat cagctctctg attttcaggg ggctttttca ttgagtataa atggacaatc
    30721 ttaaagttac tctattgtag agtggctttt gatttgatta ggagattctt ataaatatag
    30781 taaaatgaaa taagaa
//
LOCUS       DAVLTG010000021        30256 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLTG010000021 DAVLTG010000000
VERSION     DAVLTG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.021"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..139)
                     /locus_tag="VYN12_001023"
     CDS             complement(<1..139)
                     /locus_tag="VYN12_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415428.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     EC"
     gene            complement(237..1727)
                     /locus_tag="VYN12_001024"
     CDS             complement(237..1727)
                     /locus_tag="VYN12_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1415429.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLYNICSG"
     gene            1893..2057
                     /locus_tag="VYN12_001025"
     CDS             1893..2057
                     /locus_tag="VYN12_001025"
                     /inference="COORDINATES: protein motif:HMM:NF024803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1415430.1"
                     /translation="MVPLKSENGYRTYSQEDLERLQVILYYKYLGFSLEKIAELLKEE
                     RTDLLLHLTR"
     gene            2058..2564
                     /locus_tag="VYN12_001026"
     CDS             2058..2564
                     /locus_tag="VYN12_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TipAS antibiotic-recognition domain-containing
                     protein"
                     /protein_id="HEV1415431.1"
                     /translation="MDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQD
                     NQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAFNQVFQTLAQNLQVGLPATATENQ
                     EQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKENIDKFGSETAQYTSDAIAAYV
                     QTNAEKIG"
     gene            complement(2584..3039)
                     /locus_tag="VYN12_001027"
     CDS             complement(2584..3039)
                     /locus_tag="VYN12_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1415432.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(3059..4234)
                     /locus_tag="VYN12_001028"
     CDS             complement(3059..4234)
                     /locus_tag="VYN12_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1415433.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(4293..5138)
                     /locus_tag="VYN12_001029"
     CDS             complement(4293..5138)
                     /locus_tag="VYN12_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1415434.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            5263..5820
                     /locus_tag="VYN12_001030"
     CDS             5263..5820
                     /locus_tag="VYN12_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1415435.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            5839..6306
                     /locus_tag="VYN12_001031"
     CDS             5839..6306
                     /locus_tag="VYN12_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1415436.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            6395..7024
                     /gene="upp"
                     /locus_tag="VYN12_001032"
     CDS             6395..7024
                     /gene="upp"
                     /locus_tag="VYN12_001032"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1415437.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            7198..7788
                     /gene="clpP"
                     /locus_tag="VYN12_001033"
     CDS             7198..7788
                     /gene="clpP"
                     /locus_tag="VYN12_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1415438.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            7867..8115
                     /locus_tag="VYN12_001034"
     CDS             7867..8115
                     /locus_tag="VYN12_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1415439.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            8216..9376
                     /locus_tag="VYN12_001035"
     CDS             8216..9376
                     /locus_tag="VYN12_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1415440.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            9644..10513
                     /locus_tag="VYN12_001036"
     CDS             9644..10513
                     /locus_tag="VYN12_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1415441.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            10517..11473
                     /locus_tag="VYN12_001037"
     CDS             10517..11473
                     /locus_tag="VYN12_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1415442.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            11473..12237
                     /locus_tag="VYN12_001038"
     CDS             11473..12237
                     /locus_tag="VYN12_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415443.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            12237..12947
                     /locus_tag="VYN12_001039"
     CDS             12237..12947
                     /locus_tag="VYN12_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415444.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            13361..14017
                     /locus_tag="VYN12_001040"
     CDS             13361..14017
                     /locus_tag="VYN12_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1415445.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            14125..15220
                     /gene="prfB"
                     /locus_tag="VYN12_001041"
     CDS             join(14125..14196,14198..15220)
                     /gene="prfB"
                     /locus_tag="VYN12_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1415446.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            15238..15930
                     /gene="ftsE"
                     /locus_tag="VYN12_001042"
     CDS             15238..15930
                     /gene="ftsE"
                     /locus_tag="VYN12_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1415447.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            15923..16849
                     /locus_tag="VYN12_001043"
     CDS             15923..16849
                     /locus_tag="VYN12_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415448.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVETNTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            17135..19315
                     /locus_tag="VYN12_001044"
     CDS             17135..19315
                     /locus_tag="VYN12_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1415449.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            19367..20182
                     /locus_tag="VYN12_001045"
     CDS             19367..20182
                     /locus_tag="VYN12_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1415450.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            20322..21665
                     /locus_tag="VYN12_001046"
     CDS             20322..21665
                     /locus_tag="VYN12_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1415451.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            21880..23070
                     /locus_tag="VYN12_001047"
     CDS             21880..23070
                     /locus_tag="VYN12_001047"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1415452.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            23623..24558
                     /locus_tag="VYN12_001048"
     CDS             23623..24558
                     /locus_tag="VYN12_001048"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1415453.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFTYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            24592..25629
                     /locus_tag="VYN12_001049"
     CDS             24592..25629
                     /locus_tag="VYN12_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1415454.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            25770..26375
                     /locus_tag="VYN12_001050"
     CDS             25770..26375
                     /locus_tag="VYN12_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1415455.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            26533..27063
                     /locus_tag="VYN12_001051"
     CDS             26533..27063
                     /locus_tag="VYN12_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1415456.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            27084..27986
                     /locus_tag="VYN12_001052"
     CDS             27084..27986
                     /locus_tag="VYN12_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEV1415457.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDID
                     AACGQLRSNTMKRDRQKAVAAVNP"
     gene            27986..28468
                     /locus_tag="VYN12_001053"
     CDS             27986..28468
                     /locus_tag="VYN12_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1415458.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNIFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            28470..30011
                     /locus_tag="VYN12_001054"
     CDS             28470..30011
                     /locus_tag="VYN12_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1415459.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(30066..>30256)
                     /locus_tag="VYN12_001055"
     CDS             complement(30066..>30256)
                     /locus_tag="VYN12_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415460.1"
                     /translation="KEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRI
                     FIALNIKKERTNFVLSRA"
BASE COUNT         9198 a         5637 c         6595 g         8826 t
ORIGIN      
        1 cgcactcagg gcaagatggt gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgtat
       61 ccttattgat gatgtctaaa atctggatat tagggtcttt aatgtctagt aattttgtga
      121 taaaatgtaa ttgttccata tgaatctttc taatgagttg ttttgtcgct tttcattata
      181 gatcttatgg gatttttttc tacaataaaa taggctccat aatatctata gtggatttac
      241 ccactacaaa tattatagag ccctttttga ttacataaat tgggcgatga agaccacgat
      301 gatgattgga atgacggaac gaagaaacga agaaggaaga gccagacttg gaacagtcct
      361 tgtttccatg ctctttcatc gagatggagt tcctccattg caagagcctt tttaaagata
      421 tagcctgtaa aaagtgaaag gtagagagct ccaaatggca tgaggagatt gggaaccaag
      481 aagttcatag cgtcaaagaa ggtcttacca aaaatgtgaa catccgccat gacaccgtaa
      541 gatagggctg aaggaatgcc aaagacaaag gtcaaaattc ctaaaataac actccatttg
      601 gcacgtttgc tgttatcctg gttggtgata ttgcccacat tgatctccag catcacgaca
      661 gaagaagtga cagtcgcaaa gaggaagagg acgtagaaaa tggttccaaa aggcatcttg
      721 tcaaagagtt gaggcaagac gataaagagc aagctcggtc ccccttcaga ctggatattg
      781 aagggggacc gagcttggaa aatggctaga cctgccatga tggatatcga gatattcatg
      841 gctacgatgg agattcctga ctggactaga ttggttttct tgtccaagta agaagcatag
      901 gtcaacatga ctgtaacccc tagtgagagg gcaaagaaag attgtcccag agcatagagg
      961 agaccagcgc tagtcagttt tgaaaagtct ggtttgagga agtaaagaac cccttccatg
     1021 gcatttggca aactgagaga gcgaccgatg ataacaacaa agatgataaa gagcaggggc
     1081 atcatgactt tcgaagctct ttcaatccct ttttgaaccc cacgtgatac aataaagata
     1141 tttaataaga taaaggctgc ttgagctcct agggcaatgg ctggatttga aatgattgaa
     1201 gtaaataact gagcataatc acccgttcca ccaagttgga acaatttccc aaactcaata
     1261 cctagataga ctagaatcca tcctccgata acactgtaaa aagataagag gataaagagg
     1321 gcaaaggcgc caatccaacc gataaagttg tacttgttat tcttgcccag ttttccaaag
     1381 gttttgatag cggaaacgcc agcactacgg ccaagggcaa actcagccag caggagaggg
     1441 aaaccgatta aaatagtgga aatgagaaag attagtaaaa agcctccacc gccattagca
     1501 gcagtcatgt agggaaactt ccaaacggaa ccaagcccga tgaccgagcc agcagatgct
     1561 agaataaagc caagtttcga cccccattgt gatttttctg acatagttaa actctgatct
     1621 cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt ttgattgata
     1681 gacttgacta tcctattatg ttttctaagg tctgtcaaga aaaccatttt caagttttca
     1741 cacctttctc aaaaacgctt gactctgacc taaggggagg ggttatacta tcattgtaag
     1801 gaggaaatca tgtaccatat aaaagaagct gcgcagcttt caggtgtctc tgtcaagacc
     1861 ctgccctgca tcactatgac aagataggac tcttggtccc cttaaagtcg gaaaacggct
     1921 atcgaaccta tagtcaagag gatttggaac gccttcaggt cattctttac tacaaatatc
     1981 taggcttttc tttagagaaa atagcagaac tgttaaagga agaaaggaca gatttattgc
     2041 tccatttgac taggtagttg gactatctaa ctcgcgaaag gcaacatctg gataccttga
     2101 tttccacctt gcaaaaaact attcaagaac aaaaaggaga aagaaaaatg accattgagg
     2161 aaaaattcac gggatttagc tatcaagaca atcaaaaata ccaccaagaa gcggtagaga
     2221 aatatggtca agaagtcatg ggacaagcgc tcgaacgcca aaaaggtcac gaagacgagg
     2281 ctacggccgc ctttaaccaa gtctttcaaa ctttggcaca aaatcttcaa gttggtttac
     2341 ctgcaacagc aaccgaaaac caggagcaag cagccaagct cttgcaagcc attcgcactt
     2401 atggatttga ctgctctatt gaggtattcg gtcatatcgg taaaggttac gtctacaacc
     2461 cagagtttaa ggaaaacatt gacaagtttg gttctgaaac agcccagtac acgtcagatg
     2521 ccattgcggc ttacgttcag acaaatgcag aaaaaatagg ctaggaattt cctagcctat
     2581 tttttacttc aaatcataaa gccagtcgtc accgtttttg tagtaaaaga attcactgag
     2641 atcttcttct agaaacacac gaagcatatc agacatatca tcggttgcaa gttttagatg
     2701 agaaagattt tcaaagtcct cccaccaaac tttcccttcg tctgaagact ggagttcacc
     2761 agtaaagtgt tctgtcttgt aaaaaaggac gacataacga taatccttgt cgtcatacca
     2821 gtttttgata ccacagagtt ggggtttgga aatgatcaga ccagtttctt ctttcacttc
     2881 acgaatgaca gcatcgacaa aggattcgcc acgttcaaca tgaccaccag gaaaagtaat
     2941 gccagaccag tcgggactaa ctcggtcttg gaccaggacc ttatctccgt ttttaatcat
     3001 acacatgtta acaaattcga ctgcctctct tctgttcatt cttcacaacc tttaatcttt
     3061 aatcataatg cagacttccc gccacccagc cggtacagag ggcagaagtg atgttaaagc
     3121 cacccgtgtg ggcattgata tccataactt cgcctgcaaa gtggaggcca ggtaccagct
     3181 tactttcaag ggttttagga ttgatttcct tgagactgac tccacccttg gtaacaaagg
     3241 actttgcaag ggacattttt ccagttacag gaattttaag ttctttaatg gactggacaa
     3301 gttgttctcg ttccttttca gtcagttgtt tgactttttc aggatatcct tgtacaaaaa
     3361 attcggccaa gcgttctggt aacaaggttt ttaaagcgtt tttcaaggat ttttcccgat
     3421 tttcttctag aaatgtaacc aagtccttct cagaaagttg aggcaaaaca tcgagtgaga
     3481 gaacctcccc acctttgaca aagctagaca tgcgtagggc agcaggacct gacaaaccaa
     3541 agtgggtaaa gagtaaatca tgagtgatga catgcttacc ataacttagg gtcacatcgt
     3601 ccagagaaat cccttgtaag gctttatgtg gaaaatctgt taataaagga ctttcagcag
     3661 cctcaagatc ggtgatggta tgcttaaaat ggcgagcaat ctcgtgacca aaaccagtcg
     3721 aaccagtcga aggataagac ttaccacctg ttgtgacaat gagtttctca caagtgaagg
     3781 tttgatccgc tgacttaagg acaaactggt catctacttt tttaacagaa acgatttcta
     3841 tttgagtagc aacttgacca cctagttcgg tgattttctt ttccaaagct tcgataatag
     3901 tccgagactt gtcactggct ggaaagacgc gtccgtggtc ttcgacctta agtttaacac
     3961 cattttctgt aaaaaagttg atgatgtcat gattatcgaa ctgggagaaa acactgtaaa
     4021 gaaagcgtcc gtttccagga attccagcta gcaggttgtc taagctacca ttgttggtca
     4081 cattgcaacg tcccccacca gtcccagcta atttttttcc aagtttccga tttttttcga
     4141 tgaggagggt tttctgtcca taaaagctac tggaaatcgt agccatcata ccagcaggtc
     4201 ccccaccgat gacaatagta tcaaaatgtt tcatagctct attgtaccac aaaaaaacaa
     4261 gagatgatgg tcacctcttg tcaagaatgc aattaatcaa tttcatagcc catcagcaaa
     4321 ccgccctctt ctgcatagaa actgcagaga ccagaggttg gtagaatttt aatatccgct
     4381 tgtgggaagg tttcacggat tcgctctgag agctgttgac aacatttttc gttattgcgt
     4441 tgggccatga caatacggcc accagcatat ccagctttta ctaactcatc ataggcagct
     4501 tgaactgatt tctttgatcc ccttgctttt tgtagcaatt cgagagttcc agtttcacta
     4561 gcttttccga ccatacgaat gttgagaagg ccaacgaccg taccgataag cttgctcaaa
     4621 cggccgttct tcaccaagtt atcgactttg gctaggacaa agagcaactt agttttttct
     4681 tgataggcag tgatagcttc aaccacttct tcaaaagaca agccctggtc aatcaagtca
     4741 ttcaattttt ctacgagtag gtcaacttca ccaccagcag ataaactatc aatcacatga
     4801 atcttagtgt caggatggtc ttctagataa atattctttg ctagttgagc actattgtga
     4861 ctgccagaaa gggtacctgt gatggttact aggaaaatgt ttttggcacc ttcaaatgct
     4921 cgcaaatagt catctgggct tggacaagcc gattttgaag cttctgcagt tgcatacatg
     4981 gtttccatca tttggtcaat atcgagactg gcgtcatcaa caaagacctg atcagctact
     5041 tgaatggtta aggggacact tacaaaggtt gtgttaatag ctggtgttgg cagttgacga
     5101 taatcacaac cagagtcagc aataattttc caagtcatag aaattctcca tctttgtcag
     5161 ttatacattg acaaaggttc tgtctttttt tacaattata tcatgaaaac ccttgaaaca
     5221 aaagcatcat ccgtctgttg tgacaagtag aaagaaaatg ttatgtctga acgtagaatc
     5281 tctgaaaagt ctcttgaaaa tctcagaaaa tcaaaccaag aatccaattt attaaccaga
     5341 gaagccattg aaacagccct cttgcaactc ttggaaaaaa aggagctgac caagattagt
     5401 atttctgaat tggtcaaacg tgcaggtgtt tcgcgtgcgg ccttttatcg caattatgac
     5461 tccaaagagg aaattttaga gagcgtcttt aaacgaactg tccacaatat tatggaacag
     5521 ctgcatcatt acgatttaaa gacagacctt tatttggttt gggttcacct tttccgggag
     5581 gccagaaagg aagctagagt gattcaattg gccttggatt accatctgga aaaaatcttt
     5641 gtccaagcca tgcaggaatt tctagaaaaa taccatggga aatcaaaagg tgtcagctct
     5701 tatcttcatt ccttctggag ctcagccatc gtctctgtcc ttctaaaatg gatcaaggat
     5761 ggcatgaagg taccagctga aaagattgca gatttaggtt taccattttt taaaaaatag
     5821 agaaaaagga gaaaagagat gactgaaaaa agactggcct gggatgagta ttttgcagcc
     5881 caagccctac taattgcgaa tcgttccact tgtaaacgtg ctaaagtggg cgcgattctg
     5941 gtaaaagata ataaggttat ttccactggt tacaatggtt cggtgtcagg gactgagcat
     6001 tgtattgatc acgaatgttt ggtcattgaa ggccactgtg ttcgcaccct tcacgctgag
     6061 gtcaatgcta tccttcaagg tgctgagcgt ggtgttccca aaggctttac agcctatgta
     6121 acccattttc cttgtctcaa ctgtacaaaa caattgcttc aggtcggctg caagcgcgtg
     6181 gtttatatca accagtaccg aatggacgac tacgcccaat acctttatca agaaaaaggg
     6241 acagaattga cccatttacc acttgagaca gtacagacag ctcttaaaga ggctgatcta
     6301 atgtaaaaat tatcaaaaat aaatggctta gaaagatttt taaaccgttt tttggtataa
     6361 taagaagaat aaattgaaag aaggaattcc aaaaatggga aaaattgaag ttattaatca
     6421 cccactgatt caacacaaat tgtcaatctt gcgtcgtaca gatacttcta caaaagcttt
     6481 tcgtgagcta gtagatgaga ttgcaatgtt gatggggtat gaagtacttc gtgatcttcc
     6541 actagaagat gtggaaatcg aaacaccaat tacaaaaaca gttcaaaaac aattggcagg
     6601 taagaaattg gccatcgtcc caatcttgcg tgcaggtatc gggatggttg atggtctctt
     6661 gagcttggtt ccagctgcta aagttggcca catcggtatg taccgtgatg aagaaacact
     6721 tcaaccagtt gaatacttgg tgaaattgcc tgaggacatt gaccaacgtc aaatttttat
     6781 agtagaccca atgttggcaa caggtggctc agcaatcttg gctgttgatt ctcttaaaaa
     6841 acgtggcgca tcaaatatca aatttgtctg ccttgtatct gctccagagg gtgtaaaagc
     6901 ccttcaagaa gctcatccag atgtagaaat ctttacagca gccttggatg aacgtttgaa
     6961 cgaacacggt tatatcgttc caggtcttgg agatgctgga gaccgcttgt tcggtacaaa
     7021 ataagatcga aaagaagaat gacttggaaa agtatttcca gtcacgaaag gaggttgggt
     7081 ttttgtttct gtctaatgaa agcagagcaa aaatttgacc ttttttgacc aagatattat
     7141 aatagtctta tcttcagtca tttgaccaac aaaattaaaa ctcaaaagga gaaatgaatg
     7201 attcctgtag ttattgaaca aacaagccgt ggagaacgtt cttacgatat ttactcacgt
     7261 cttctcaaag accgcatcat tatgctgaca ggtccggttg aagacaatat ggctaactct
     7321 gttattgccc aattgctttt cttggatgcc caagatagta caaaagatat ttacctttat
     7381 gtcaatacac caggtggttc tgtttcagct ggtttggcaa tcgtagatac catgaacttt
     7441 atcaaggcag atgtccaaac cattgttatg ggaatggctg catctatggg aacagtcatc
     7501 gcatcaagtg gagcaaaagg caaacgtttc atgcttccaa atgctgaata catgattcac
     7561 caaccaatgg gcggtacagg tggtggtacc caacaaactg atatggctat cgctgcagaa
     7621 cacttgctca aaactcgtaa taccttggaa aaaatcttgg ctgaaaattc aggtcagtca
     7681 atggaaaaag tccatgcaga tgcagaacgt gataactgga tgagcgccca ggaaacactt
     7741 gaatatggct ttattgatga aattatggcc aacaattcat tgaactaatg atgatagaag
     7801 gcaaactcga ctgggtttgc tttttttggt ataataggga gagatttctt agaaagagga
     7861 tttatcatgt ttgaaaaagt caatcgctct ggcttgatta tctatcttta ctataatcgt
     7921 gatgccaaaa aactgcagga ttatggagat attacctatc attccaagaa acatcgttac
     7981 ttacaactct atgttccaac tcaagaagtg gagcaattgg tcggacgctt gagcaaggaa
     8041 aaatttatta aaaaagttag ggtttgtcat atccaagagt tggaaacacc ctttgtgggc
     8101 aatctttatc gataggaaaa cgttatcatc gaaaaagttc aaggaaaaca ttgacaattt
     8161 tctgataatt cggtatattc ttaacagact atttaagaaa taaggagaca aaaagatgaa
     8221 gaaaaaattt gccctatcgt ttgtggcgct tgcaagtgta gcacttcttg cagcctgtgg
     8281 agaagtgaag tctggagcag tcaacactgc tggtaactca gtagaggaaa agacaattaa
     8341 aatcgggttt aactttgaag aatcaggttc tttagctgca tacggaacag ctgaacaaaa
     8401 aggtgcccaa ttggctgttg atgaaatcaa tgccgcaggt ggtatcgatg gaaaacaaat
     8461 cgaagtagtc gataaagata ataagtctga aacagctgag gctgcttcag ttacaactaa
     8521 ccttgtaacc caatctaaag tatcagcagt cgtaggacct gcaacatctg gtgcgactgc
     8581 agctgcggta gcgaacgcta caaaagcagg tgttcccttg atctcaccaa gtgcgactca
     8641 agatggattg actaaaggtc aagattacct ctttattgga actttccaag atagcttcca
     8701 aggaaaaatt atctcaaact atgtttctga aaaattaaat gctaagaaag ttgttcttta
     8761 cactgacaat gccagtgact atgctaaagg gattgccaaa tctttccgcg agtcatacaa
     8821 gggtgaaatc gttgcagatg aaactttcgt agcaggtgac acagacttcc aagcagccct
     8881 tacaaaaatg aaagggaaag actttgatgc tatcgttgtt cctggttact ataatgaggc
     8941 tggtaagatt gtaaaccaag cgcgtggtat gggaattgac aaaccaatcg ttggtggtga
     9001 tggattcaac ggtgaggagt ttgtacaaca agcaactgct gaaaaagcat caaacatcta
     9061 ctttatctca ggcttctcaa ctactgtaga agtttcagct aaagctaaag ccttccttga
     9121 cgcttaccgt gctaagtaca atgaagagcc ttcaacattt gcagccttgg cttatgattc
     9181 agttcacctt gtagcaaacg cagcaaaagg tgctaaaaat tcaggtgaaa tcaaggataa
     9241 ccttgctaaa acaaaagatt ttgaaggtgt aactggtcaa acaagcttcg atgcagacca
     9301 caacacagtc aaaactgctt acatgatgac catgaacaat ggtaaagttg aagcagcaga
     9361 agttgtaaaa ccataataga aaaatgttga aatagggaat gagcctttga ctcactccct
     9421 gtttcgatat ttaatactct tcgaaaatct cttcaaactg cgtcaacgtc gccttggatt
     9481 atatatgtga ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcaacc
     9541 tgcggctagt ttcctagttt gctctttgat tttcattgag tataagaacc tatcaaaaag
     9601 tgagggaaac ccctcggaat tataaataga aagagtgaat cttatgctcc aacaactcgt
     9661 aaatggtttg attctaggta gtgtttacgc gctgttagcc ctaggatata ccatggttta
     9721 cggaattatc aagctcatca acttcgccca tggtgatatt tatatgatgg gagcctttat
     9781 cggttatttc ttgatcaatt ctttccaaat gaatttcttt gtagcgctta ttgtagctat
     9841 gctagcgaca gctattcttg gtgtcgtgat tgagtttctt gcttaccgac ctttgcgcca
     9901 ctctactcgt attgctgttt tgattacagc tattggggtt tctttcctat tggagtatgg
     9961 aatggtctat ctggttggtg ccaatacccg tgccttccct caagcgattc aaacagttcg
    10021 atatgatttg ggaccaatta gcttaacaaa tgtgcagtta atgattttgg ctatttcctt
    10081 gattttgatg attttgttac aagtcattgt ccaaaagact aagatgggga aagccatgcg
    10141 tgcagtatca gtagatagcg acgcggcgca attgatgggg atcaatgtaa accgtacgat
    10201 tagctttacc ttcgctttgg gttctgctct tgcgggtgcg gctggtgttc tgattgctct
    10261 ttattataac tctcttgagc ctttgatggg ggttactcca ggtcttaaat ctttcgttgc
    10321 cgcagtactt ggtggtatcg gaattattcc tggtgcggct cttggtggct ttgtgattgg
    10381 tctattggaa acctttgcga ctgcctttgg gatgtcagat ttccgtgatg ccattgttta
    10441 tggaatcttg ttgttgatct tgattgtccg cccagctggt atccttggta agaatgtgaa
    10501 agagaaggtg taaacgatga aggaaaattt aaaagttaat attctatggt tactcctttt
    10561 gttagctggc tatagcttga ttagtgtact ggtttcagtc ggagtactta atctattcta
    10621 tgtacagatt ttacagcaaa ttggaattaa tattattttg gctgttggtc tcaacttaat
    10681 cgttggtttt tcaggacaat tttcacttgg tcatgctggt ttcatggcga ttggtgccta
    10741 tgcagcagct attattggtt ctaaattacc aacctacggt gccttctttg gagctatgct
    10801 tgtaggggct ttgctttcag gagcagttgc cttacttgtc ggcattccaa ccttgcgctt
    10861 gaagggggac tatcttgcgg tagcaactct gggtgtttct gaaattatcc gtatctttat
    10921 catcaatggt ggaagcctta caaatggtgc ggcaggtatc ttagggattc ctaactttac
    10981 aacttggcaa atggtttact tctttgtcgt gattacaacc attgcaacct tgaacttctt
    11041 gcgtagccca attggtcgtt caaccctctc tgttcgtgaa gatgaaatcg ctgctgagtc
    11101 agttggggtt aatacgacta aaattaaaat catcgctttt gtctttggtg ccattactgc
    11161 aagtattgct gggtcacttc aggcaggatt tatcgggtct gttgtaccga aagattacac
    11221 cttcatcaac tcaatcaacg ttttgattat tgttgtattt ggtggactcg gttccattac
    11281 aggtgcgatt gtttcggcta ttgttctggg aattttgaat atgcttctcc aagatgttgc
    11341 tagtgtgcgt atgattattt acgctttggc cttggtattg gtaatgattt tcagaccagg
    11401 tggactcctt ggaacatggg aactgagcct atcacgtttc tttaaaaaat ctaagaagga
    11461 ggaacaaaac taatggcatt acttgaagta aaacagttaa ccaaacattt tggtggtcta
    11521 acagctgttg gagatgtgac tcttgaattg aacgaagggg aactggttgg attaatcggt
    11581 ccaaacggag ctgggaaaac cacccttttc aaccttttga ccggtgttta tgaaccaagc
    11641 gagggaacag taaccctaga tggtcacctt ttgaatggga aatcacctta taagattgcc
    11701 tctttgggac ttggacgtac tttccaaaat atccgtctct ttaaagattt aacagtttta
    11761 gacaatgttt tgattgcttt tggaaaccat cacaaacaac atgtttttac tagtttctta
    11821 cgcttaccag ctttttacaa gagtgaaaaa gaattaaagg ctaaagcttt ggaattgttg
    11881 aaaatctttg atttagatgg tgatgcagag actcttgcta aaaatctttc ctacggacaa
    11941 caacgtcgtt tggaaattgt tcgtgccctt gctacggaac ctaaaattct cttcttagat
    12001 gaaccagcag caggtatgaa cccacaggaa acagccgaat tgactgagtt aattcgtcgt
    12061 atcaaagatg aatttaagat tacaatcatg ttgattgaac acgatatgaa tctggtcatg
    12121 gaagtaacag aacgtatcta cgtacttgaa tatggccgtt taattgctca aggaactcca
    12181 gacgaaatta agaccaataa acgcgttatc gaagcttatc taggaggtga agcctaatgt
    12241 ctatgttaaa agttgaaaat ctttctgtgc attacggtat gatccaagca gtccgtgatg
    12301 taagctttga agttaatgaa ggagaagttg tttcccttat cggtgccaac ggtgcaggta
    12361 agacaactat tcttcgcaca ttgtcaggtt tggttcgacc aagttcagga aagattgaat
    12421 ttttaggtca agaaatccaa aaaatgccag ctcagaaaat tgtggcaggt ggtctttcac
    12481 aagttccaga aggacgccac gtctttcctg gcttgactgt tatggaaaat cttgaaatgg
    12541 gagctttctt aaagaaaaat cgtgaagaaa atcaagctaa cttgaagaag gttttctcac
    12601 gctttcctcg tcttgaagaa cgtaagaacc aagatgcagc tactctttca ggaggggaac
    12661 aacaaatgct tgccatggga cgcgctctta tgtcaacacc aaaacttctt cttttagatg
    12721 aaccatcaat gggacttgcc ccaatcttca tccaagagat ttttgatatc attcaagata
    12781 ttcagaagca aggaacaacc gtcctcttga ttgaacaaaa tgccaataaa gcacttgcaa
    12841 tctctgaccg aggatatgta ctggaaacag ggaaaatcgt cctatcagga acaggaaaag
    12901 aactcgcctc atcagaagaa gtcagaaaag catatctagg tggctaaaac aatccagtgg
    12961 attgttttag tcggcagatg aagattacga agtaatcatc attatagtct gggagactag
    13021 tttaggttgc agataaagat tgcgaagcaa tcatcaaatc cagtggattg ttttagtcgg
    13081 cagatggaga ttacgaagta atcatcaata tagtccgggg gaccttttta gtcggtagat
    13141 tgagattgca aacaaatctg catctacatt gaaagcttaa tttctaataa ttgaaaaaat
    13201 cgaatgaaaa atttcttacc ttcattcaca gagctcgatt tcagagctct ttttgctagc
    13261 ttattcatac ttttctgaat ttcgaaaaag aaatgtaagc gtttgataga tttacaaaaa
    13321 gattgtataa tagggataag aatagaaaag gagaagtctc atggcagtta aagattttat
    13381 gacccgcaag gtagtttata ttagtccaga tacaacagta tctcatgcag cagatttgat
    13441 gagagagcaa ggtttgcacc gtctgcctgt tatcgaaaat gatcaattag ttggtttggt
    13501 gactgaggga accattgcac aagcaagtcc atctaaagca acaagtcttt ctatctatga
    13561 gatgaattat cttctgaata agacaaaagt aaaagatgtc atgattcgcg atgttgtcac
    13621 tgtctcaggc tatgctagtc tagaagatgc aacttatctg atgttgaaaa ataagattag
    13681 tattctccct gtcgtagata accatcaagt atacggagtt attactgacc gtgacgtttt
    13741 ccaagccttt cttgaaattg caggttatgg cgaagaaggg attcgtgtac gctttgttac
    13801 agaagatgaa gttggtgttc ttggaaaaat tgtttctttg attgtagaag aaaatttgaa
    13861 tatctcccat acagtcaata ttccgcgtaa ggatggtaag gtgattatcg aagtgcaaat
    13921 cgatggatca attgatttac cagccttgaa agaaaaattt gaagcaaatg gtattcaagt
    13981 ggaagaaatc gctcgcactt cagcaaaagt cttgtaagaa gggaagccca aaggcttctt
    14041 ttttcatgaa aaggggatta gagaaaaaga tggaaagaaa tgataaaata tgctataatg
    14101 aaataatgta aaaaaggagt atttatggac atttcagtaa ttcgtcagaa aattgacgca
    14161 aatcgtgaaa aattagcttc tttcaggggg tctctttgac ctcgaagggc tagaggaaga
    14221 gattgccatc ttggaaaaca agatgacaga acctgatttt tggaacgata atattgcagc
    14281 ccaaaaaacg tcgcaagaat taaatgaatt aaaaaacact tacaatacct tccataagat
    14341 ggaagagttg caggatgaag tcgaaatttt attggatttt ttggctgaag acgagtcagt
    14401 gcatgatgaa ctggtagcgc agttagccga acttgataag ataatgacca gctacgagat
    14461 gactctactc ttgtcagaac cttatgacca caacaatgcc atcttggaaa tccatccagg
    14521 ttctggtggt actgaggcgc aggactgggg tgatatgttg cttcgtatgt atactcgtta
    14581 tggtaatgct aaaggcttta aagtggaagt gttggattac caagcaggtg atgaggctgg
    14641 tattaagtcg gtaactttat catttgaagg gcctaatgcc tatggtctcc tcaagtcaga
    14701 aatgggtgtt caccgcttag tgcgaatctc accatttgac tctgccaaac gtcgccatac
    14761 ctctttcaca tctgtagaag tgatgccaga attggatgat actattgaag tggaaatccg
    14821 tgaagatgat atcaagatgg ataccttccg ttcaggtggt gccggtggac aaaacgtcaa
    14881 taaggtttca acaggtgtac gtttaaccca cattccaact ggaattgttg tccaatcaac
    14941 agtggatcgt acccagtatg gaaatagaga tcgtgccatg aagatgttgc aggctaagct
    15001 ctatcaaatg gagcaagaga agaaggctgc agaggtagat tctctcaaag gtgagaaaaa
    15061 ggagatcact tggggaagcc aaatccgttc ttatgtcttc acgccttata ctatggtaaa
    15121 agatcaccga actagctttg aggttgctca ggtagataag gttatggatg gggacttaga
    15181 tggttttatc gatgcttatc tcaagtggcg aattagctaa gatagaaagg aactcacatg
    15241 tcaattattg aaatgagaga tgtcgttaaa aaatacgaca acggaacgac tgctctacgc
    15301 ggtgtttcgg ttagcgttca accgggggaa tttgcttaca tcgtaggacc ttcaggagca
    15361 gggaagtcaa cttttattcg ttctctgtat cgtgaagtaa aaatcgataa aggaagccta
    15421 tcagttgctg gttttaatct ggttaagatc aaaaagaaag atatcccgct tctacgtcgt
    15481 agtgttgggg ttgtcttcca ggattataaa ttgttaccaa agaaaactgt ctatgaaaat
    15541 attgcttacg ctatggaagt aatcggggaa aatcgccgta atatcaaaag acgagtgatg
    15601 gaagttttgg acttggttgg attgaagcat aaggttcgtt ctttcccaaa tgaactctca
    15661 ggtggggagc aacagcggat tgcgattgcg cgtgcaattg taaataatcc caaagtattg
    15721 atagctgatg agccaacagg aaatctggat ccggataatt catgggaaat tatgaatctt
    15781 ttggaacgga ttaacctaca aggaacaact attttgatgg cgactcataa tagccagatt
    15841 gtaaatacct tgcgccaccg tgtcattgcc attgaaaatg gccgtgtcgt tcgtgacgaa
    15901 tcaaaaggag agtatggata cgatgattag tagatttttt cgccatttat ttgaagcctt
    15961 aaaaagtttg aaacgaaatg gttggatgac agtagctgct gtcagttcag tcatgattac
    16021 tttgaccttg gtggcaatat ttgcatctgt tattttcaat acagcgaaac tagctacaga
    16081 tattgaaaat aatgtccgtg tagtagttta tatccgaaag gatgtggaag ataatagtca
    16141 gacaattgaa aaagaaggtc aaactgttac aaataatgac taccacaagg tatatgattc
    16201 tttgaagaac atgtctacgg ttaaaagtgt taccttttca agtaaagaag aacaatatga
    16261 aaaattaacc gagataatgg gagataactg gaaaatcttt gaaggagatg ccaatcctct
    16321 ctatgatgcc tatattgtag agacaaacac tccaaatgat gtaaaaacta tagccgaaga
    16381 tgctaaaaaa attgaaggtg tctctgaggt tcaagatggc ggtgccaata cagaaagact
    16441 cttcaagtta gcttcattta tccgtgtttg gggactaggg attgctgctt tgttaatttt
    16501 tatcgcagtt ttcttgattt caaataccat tcgtattacc attatttccc gcagtcgcga
    16561 aattcaaatc atgcgcttgg tcggagctaa aaacagttat atccgtggac cgttcttgtt
    16621 agaaggagcc tttatcggtt tattgggagc tatcgcacca tctgttttgg tctttattgt
    16681 ttatcaaatt gtttaccaat ctgtcaacaa atcgttggta gggcaaaatc tatccatgat
    16741 tagtccagat ttatttagtc cgttgatgat tgccctacta tttgtgattg gggttttcat
    16801 tggttcattg ggatcaggaa tatccatgcg ccgattcttg aaggtttagg taaaatagct
    16861 gcttttatga ggagattgta aaatctcctt ttttgctaca agagtttttg aaaagagatg
    16921 cgcagaagaa aagagcttcc aaagaagtcc cccagagaag acttcttgat ggctaatttg
    16981 aacttgaaat ttggcgcact agaaattttt tagaaaaaag tgtaattttt ttataaaagc
    17041 ctttacaaaa aaaattaaag tggtataatt aaatcataga aagtgcaaac gttttcgtaa
    17101 aacgtttgcc taaataaaaa taaaggagat ttgaatgatg aaagatacat tcaaaaatgt
    17161 cttgtctttc gaattttggc aaaaattcgg taaggctttg atggtagtta tcgcggttat
    17221 gccggctgct ggtttgatga tttcaatcgg taagtctatc gtgatgatta acccaacctt
    17281 tgcaccactt gtcatcacag gtggaattct tgagcaaatc ggttgggggg ttatcggtaa
    17341 ccttcacatt ttgtttgccc tagccattgg aggaagctgg gctaaagaac gtgctggtgg
    17401 tgctttcgcc gctggtcttg ctttcatctt gattaaccgt atcactggta caatctttgg
    17461 tgtatcaggc gatatgttga aaaatccaga tgctatggta actactttct ttggtggttc
    17521 aatcaaagtt gctgattact ttatcagtgt tcttgaagct ccagccttga acatgggggt
    17581 attcgtaggg attatctcag gttttgtagg ggcaactgct tacaacaaat actacaactt
    17641 ccgtaaactt cctgatgcac tttcattctt caacgggaaa cgtttcgtac catttgtagt
    17701 tattcttcgt tcagcaatcg ctgcaattct acttgctgct ttctggccag tagttcaaac
    17761 aggtatcaat aacttcggta tctggattgc caactcacaa gaaactgctc caattcttgc
    17821 accattcttg tatggtactt tggaacgttt gctcttgcca tttggtcttc accacatgtt
    17881 gactatccca atgaactaca cagctcttgg tggtacttat gacattttaa ctggtgcagc
    17941 taaaggtact caagtattcg gtcaagaccc actatggctt gcatgggtaa cagaccttgt
    18001 aaaccttaaa ggtactgatg ctagtcaata tcaacacttg ttagatacag tacatccagc
    18061 tcgtttcaaa gttggacaaa tgatcggttc attcggtatc ttgatgggtg tgattgttgc
    18121 tatctaccgt aatgttgatg ctgacaagaa acataaatac aaaggtatga tgattgcaac
    18181 agctcttgca acattcttga caggggttac tgaaccaatc gaatacatgt tcatgttcat
    18241 cgcaacacct atgtatcttg tttactcact tgttcaaggt gctgccttcg ctatggctga
    18301 cgtcgtaaac ctacgtatgc actcattcgg ttcaatcgag ttcttgactc gtacacctat
    18361 tgcaatcagt gctggtattg gtatggatat cgttaacttc gtttgggtaa ctgttctctt
    18421 tgctgtaatc atgtacttta tcgcaaactt catgattcaa aaattcaact acgcaactcc
    18481 agggcgcaac ggaaactacg aaactgctga aggttcagaa gaaaccagca gcgaagtgaa
    18541 agttgcagca ggctctcaag ctgtaaacat tatcaacctt cttggtggac gtgtaaacat
    18601 cgttgatgtt gatgcatgta tgactcgtct tcgtgtaact gttaaagatg cagataaagt
    18661 aggaaatgca gagcaatgga aagcagaagg agctatgggt cttgtgatga aaggacaagg
    18721 ggttcaagct atctacggtc caaaagctga cattttgaaa tctgatatcc aagatatcct
    18781 tgattcaggt gaaatcattc ctgaaactct tccaagccaa atgactgaag cacaacaaaa
    18841 cactgttcac ttcaaagatc ttactgagga agtttactca gtagcagacg gtcaagttgt
    18901 tgctttggaa caagtaaagg atccagtatt tgctcaaaaa atgatgggtg atggatttgc
    18961 agtagaacct gcaaatggaa acattgtatc tccagtttca ggtactgtgt caagcatctt
    19021 cccaacaaaa catgcttttg gtattgtgac ggaagcaggt cttgaagtat tggttcacat
    19081 tggtttggac acagtaagtc ttgaaggtaa accatttaca gttcatgttg ctgaaggaca
    19141 aaaagttgca gcaggagatc tccttgtcac agctgacttg gatgctatcc gtgcagcagg
    19201 acgtgaaact tcaacagtag ttgtcttcac aaatggtgat gcaattaaat cagttaaatt
    19261 agaaaaaaca ggttctcttg cagctaaaac agcagttgct aaagtagaat tgtaatatac
    19321 ttgaggttgg aagctgtatt ccaacctctt attttgggag aaaagaatga aatttttaac
    19381 actcaatact cacagttgga tggagaaaga agcagaggaa aaattccaga ttttgcttga
    19441 agatattctt gaaaaggact atgatttgat ttgtttccaa gaaatcaatc aggagatgac
    19501 ctcgtcagag gtggaggtta atgaccttta tcaagctttg ccagcagctg agcctattca
    19561 ccaagaccat tatgttagac tcttggttga aaagttgtta gagcaaggga aaaattacta
    19621 ctggacctgg gcttataacc atatcggcta tgaccgctac cacgaaggtg tggctatctt
    19681 gtctaaaaca cctattgaag ccagagaaat tttggtttca gatgtggatg atccaacaga
    19741 ctatcatact cgccgtgttg ccctagctga aactgtagtc gatggcaagg agctagcagt
    19801 tgccagtgtt catctctctt ggtgggataa aggtttccaa gaagaatggg cacgatttga
    19861 ggctgtcttg aaaaaattga acaagccact tttactagct ggagatttta acaacccagc
    19921 aggtcaggaa ggttaccaag ctattttagc tagtccatta ggcttacaag acgcatttga
    19981 agttgctcaa gagaaaagtg gtagctatac tgttccgcct gaaattgatg gctggaaagg
    20041 gaacactgaa ccccttcgaa tcgattatgt ctttactacc aaagagttag cggtggaaaa
    20101 tttacatgtc gtatttgatg gtaacaagag tccacaagtg agtgatcact atggcttgaa
    20161 tgctatatta aactggaaat aataactgaa aagaggttgg aactataaaa ttccagcctt
    20221 ttcttactag agaagctact ggaaatagcc taaataagtg agactactgt aatggaataa
    20281 aatatggtat aattgataag atagatagaa tcgaggatgt tatgtcattt acgaaatttc
    20341 aatttaaaaa ctatattaga gaagccttga aggagttaaa atttacaact ccaacagagg
    20401 tgcaagacaa gttgattcct attgttttgg caggtcgtga cctagtagga gaatcaaaaa
    20461 caggttcagg taagactcat actttcttgt taccgatttt ccagcaatta gatgaagcta
    20521 gcgatagtgt acaagcagtg attactgcac cgagtcgtga gttggctact caaatttacc
    20581 aagtagcgcg tcagatttca gctcactcag atgtcgaagt tcgtgtggtt aattatgtgg
    20641 gtggtacgga taaggctcgc cagattgaga aattggaaag caatcagcct catattgtta
    20701 ttggaacacc aggccgtatc tacgacttgg ttaaatctgg tgatttagct attcataaag
    20761 ccaagacatt tgttgttgat gaagcagata tgaccttgga tatgggattc ttggaaactg
    20821 ttgataagat tgctggcagt cttccaaaag acttgcaatt catggtcttc tcagcgacta
    20881 tcccacaaaa actgcaacca ttcttgaaaa aatacttatc aaatcctgtt atggagaaaa
    20941 ttaagaccaa aacggttatt tctgacacca ttgataattg gttgatttcg accaagggac
    21001 atgataagaa tgctcaaatt taccagttga ctcagttgat gcagccgtat ttggcaatga
    21061 tttttgttaa cactaaaacg cgtgctgatg aattgcattc atatctgact gctcaaggct
    21121 tgaaggttgc aaaaatccat ggagatattg cccctcgtga acgcaagcga atcatgaatc
    21181 aggtgcaaaa tctggatttt gagtatattg tcgcaacaga tttagcagcg cgtgggattg
    21241 acattgaagg tgtcagccat gtcatcaatg atgccattcc gcaagactta tctttttttg
    21301 ttcatcgtgt tggtcgtact ggacgaaatg gcctaccagg tacagctatt accctttatc
    21361 agccaagtga tgactcggat atccgtgagt tggagaaatt gggaatcaag tttagtccta
    21421 agatggtcaa agacggggaa tttcaagata cctatgaccg tgatcgtcgt gccaaccgtg
    21481 agaaaaaaca agataaactt gatatcgaaa tgattggttt ggttaaaaag aaaaagaaaa
    21541 aagtcaaacc gggttataag aagaaaattc aatgggcggt tgatgaaaag cgccgtaaaa
    21601 ccaagcgtgc tgaaaatcgc gctcgcggtc gtgcagagcg taaagctaaa cgccaaacat
    21661 tttaatagaa attgttggag tattgagctc caactttttt atttatgaga acgaactatc
    21721 taaaccgaaa cactacatta aagactgcaa attgcgatta aaaatggtat aatgataaag
    21781 ttatatagtc ccgataagat ggtaggtatt tattacgaag agttttccta tcagtacttt
    21841 gtaactctat aacaatattt tttaaggggg gacattttta tgtcagaacg taaattattc
    21901 acgtctgaat ctgtatctga ggggcatccg gataagattg cagaccaaat ttcagatgcg
    21961 attttggatg ctattttagc aaaggatcca gaggcgcacg ttgctgctga aacagctgta
    22021 tatactggtt ctgtccacgt ttttggtgaa atttctacaa atgcctatgt ggatattaac
    22081 cgtgtggttc gtgataccat tgcagagatt ggttatacca atacagaata tggattttct
    22141 gctgagacgg tgggagtaca cccatctttg gtggaacaat ctcctgacat cgctcaaggt
    22201 gttaacgaag ccttggaggt tcgtggaaat gctgatcaag atccactgga cttgattgga
    22261 gcaggtgacc aagggctcat gtttggattt gcagtagatg aaacagaaga gctcatgcca
    22321 ttgccaattg cactcagtca taaattggtt cgtcgtctgg cagaacttcg taagtctgga
    22381 gaaattagct atctccgtcc agatgcaaaa tcacaagtta cagttgagta cgatgaaaat
    22441 gaccgtccgg tacgtgtaga tacagtcgtt atttctactc agcatgatcc agaggccact
    22501 aatgaacaaa tccatcaaga tgtgattaac aaggtcatca aagaagttat tccatcttct
    22561 tatcttgatg ataagacaaa attctttatc aatccgacag gtcgttttgt aatcggtggt
    22621 cctcaagggg actcaggttt gactggtcgt aagattattg tagatactta tggtggctac
    22681 tctcgtcatg gtggtggtgc cttctctggt aaagatgcga ctaaggtgga tcgttcagcc
    22741 tcttatgcgg ctcgctatat tgccaagaat atcgttgcag caggccttgc taagaaggca
    22801 gaagtgcagt tggcctatgc tatcggtgtt gcgcaacctg tttctgttcg tatcgatact
    22861 ttcggtacag gaacagtagc tgaaagtcaa cttgaaaaag cggctcgtca aatctttgac
    22921 cttcgccctg cagggattat ccaaatgctg gacctcaagc gtccaattta ccgtcaaaca
    22981 tcggcttacg gtcacatggg acgtacagat attgatcttc catgggaacg tttggataag
    23041 gtagatgctt tgaaagaagc agtaaaataa gattttaaga ggggaacgtc ctctcttttt
    23101 tatagttttt aactatactg ggatactgtt ctgaaaatcc attttgcgaa agtagagatt
    23161 tacatgtata gtagattgaa actagaatag tacacctcaa cttctaaaac attgttagca
    23221 atcaatttga ctgtcctgat cgatttctcc tgttcttgtt tcattttact atatttcttt
    23281 aaaaatgata aaggttgaga tttctcctcg taatagataa tcatggggat atttcaatcc
    23341 aaagttttat tcgttatcac ttgactattg caaggttttc tagagcaaca gagtcatgga
    23401 atggactcat ggttgagatt tctccttgtt gcttggactt cattcaaaag tctgttaccc
    23461 aagccttgtt caaacttcca atacactagc tgttttcata gcatgacttc tgtactagac
    23521 tttcttttcc gaataaatag atagaaccac agaatctagt aaacctagaa ttaaaattat
    23581 ggtataatat tagcaataaa agaaatctgg aggattagaa tcatggtatc aacgaaaaca
    23641 caaattgctg gttttgagtt tgacaattgc ttgatgaatg cagcaggtgt ggcttgtatg
    23701 acgatagagg agttagaaga ggtcaaaaac tcagcggcag gaacctttgt tactaagaca
    23761 gcgaccttgg acttccgtca ggggaatcct gagccacgct accaagatgt tccacttggt
    23821 tccatcaact ctatgggctt gccaaataat ggcttagact attatttgga ttatctttta
    23881 gatttgcagg aaaaagagtc gaaccgaact ttcttcttat ctctggtcgg catgtctcca
    23941 gaggaaaccc atactatttt gaaaaaagtt caagagagtg attttcgtgg tctgactgag
    24001 ctaaatcttt cctgtccaaa tgttccaggt aaacctcaga ttgcctatga ttttgagaca
    24061 acagaccgga ttttggcaga agtgtttact tacttcacca aacctcttgg aattaaattg
    24121 ccaccttatt ttgatattgt tcactttgat caagcggcag ctattttcaa caaatatccg
    24181 ctcaagtttg tcaactgcgt taactctatc ggaaacggcc tctatataga agacgaatct
    24241 gtcgttattc ggcctaagaa tggttttggt ggaattggtg gagaatacat caaaccgact
    24301 gctctagcca atgttcacgc cttttatcaa cgtttaaatc ctcaaatcca aattatcgga
    24361 acaggtggcg ttctgactgg tcgagatgcc tttgaacaca tcctctgtgg agcaagtatg
    24421 gtgcaggtgg gaacgaccct tcacaaagaa ggcgtcagtg cttttgaccg cattaccaat
    24481 gaactgaaag caatcatggt ggaaaaaggc tacgagagct tagaagattt ccgtgggaaa
    24541 ttgcgctata ttgactaaat taaatcgaaa aatctgaaga aaggagagac gatgctagcc
    24601 attgaagaaa gtcagaagtt gactttatca aatttaccga gcctgagcct atttacaggg
    24661 acagatcagg gtcagtttga agtgatgaag agtcaagtgt tgaaacagat tgggtatgat
    24721 tctgctgacc tcaactttgc ctactttgat atgaaagaag tagtttacaa ggatgtggaa
    24781 ctggagttgg tcagccttcc tttctttgcg gatgagaaaa tcgtgatatt agattatttt
    24841 atggatatca cgactgctaa gaaacgcttt ttgacagatg atgagcttaa gtcatttgag
    24901 gaataccttg acaatccttc tccaacaacc aagttgataa tctttgcaga aggaaagctg
    24961 gatagcaaaa gacggttagt caaattactt aagcgtgatg ccaaggcctt cgatgcagta
    25021 gaagtaaaag aacaagaatt gcgccagtat ttccaaaagt ggagtcagaa acaaggtctg
    25081 cagtttacca atcattcttt tgaaaatctc ctcatcaagt cggggtttca atttagcgaa
    25141 atccagaaaa atcttctctt tttacagtcc tataaggcgg attctgttat cgaggaagag
    25201 gatattgtta acgcaattcc caagaccttg caggacaata tttttgattt aactcagttt
    25261 attctgacta aaaagatgga tcaggcgcgc gatttggtga gagacttgac cttgcaaggg
    25321 gaagatgaaa tcaaactaat tgcagtcatg ctgggacaat ttcggacttt tactcaggtg
    25381 aagattttgg cggagtctgg ccaaacagaa tcgcagattg caagtagttt aggtagttat
    25441 ctgggacgta acccaaatcc ttatcaaatc aagtttgcat taagagattc gagaggactt
    25501 tctttgagct ttctgaagca agctatttcc tatttgattg agacagacta tcagattaag
    25561 acaggtcttt atgaaaaagg tttccttttt gaaaaggcac tcttacagat tgctagtcag
    25621 gtcaattgac atttgttgaa actacaaccc gcgtcaggat tatcttgtcg tgggtttctt
    25681 gctgatttgc ttatctataa gcaaaaaact tgaaaaaagt gaatgtttgc gttatcattt
    25741 tcatatagaa agaaaaagag gtattacaga tggctattat cttaccagaa cttccatatg
    25801 catacgacgc tttggaacca tacatcgatg cggaaacaat gcatttgcac catgacaaac
    25861 accatcaaac ttatgtcaac aatgccaatg cagctttaga aaaacaccct gaaatcggtg
    25921 aagaccttga agccttgctt gctgatgtag aatctatccc agctgatatc cgtcaagcac
    25981 ttatcaacaa tggtggcgga cacttgaacc acgctctttt ctgggaattg atgactcccg
    26041 agaaaacagc tccttcagca gaactggcag cagcaatcga tgcaacattt ggttcatttg
    26101 aagaattcca agcagccttc actgcagcag caacaactcg ttttggttca ggttgggcat
    26161 ggttggttgt caacaaagaa gggaaacttg aagtgacttc aacagcaaac caagacacac
    26221 caatctcaga aggtaaaaaa ccaatcttgg gcttggacgt ttgggaacat gcttactacg
    26281 tgaaataccg caacgtgcgt cctgactaca tcaaagcttt cttttcagta atcaactgga
    26341 ataaagtaga tgaattgtac gcagctgcta aataatgata gttggaggga agaattgttc
    26401 ttctcttttt taggttataa gattctggtc tgacaaaatc gttagacttt tttcattttt
    26461 tatgagaaac gtgctaactg ctagaaatta tggtagaata aagtattaag taatcgtgga
    26521 aaaaggatat ctatgcgaaa agaaattgca cctgaattat acaactataa caagtttcct
    26581 ggtccggagt tccatttaca cggggacaag gtcgaaacgg aagggatagc tttttccttg
    26641 gttgaaaata tcaaggatgc ctttgatgtg acgactttta atcagcgttt ttcagaagtc
    26701 ttaaccaagt ttgattatat cgtgggggac tggagcaacg aacagcttcg cctacgaggt
    26761 ttttacaagg atgaccgaac agaagaaaaa cttgaaaaaa tcagtcgttt acaagactac
    26821 cttttagagt attgtagtta tggttgtgcc tattttgtct tagaaaatga agcccctaag
    26881 cgagcatcat ttgacaagaa aatgcgtaag acggaagaag aaacaccttc tagaaaagga
    26941 aagaaaccga ctcaaactaa acgaaagtcg aatgcagata agaaaaatag acgtcgtcag
    27001 aaagaccagc attctcagaa agaggacaag gaacaacgtc attttgtcat tcgtcagaag
    27061 tgagtagaga ataaggagaa gaaatgaaac cctcaattca tagtttggta catcaaacca
    27121 tgcaggaatg ggtattggag cagggagaaa agaaattccg tgcagatcaa atctgggaat
    27181 ggctctaccg taaacgtgtg cagtcatttg aagaaatgac caacctttcc aaggatttga
    27241 ttgctaagct caatgaccag tttgtggtca atcccttgaa acaacgtatt gtgcaagagt
    27301 ctgctgatgg tacagtcaaa tatctctttg aattgcctga cggtatgtta attgagactg
    27361 tactcatgcg tcaacactat ggtttatctg tctgtgtgac cactcaggtc ggctgtaata
    27421 tcggttgtac cttctgtgcc tctggtttga ttaagaagca gcgtgacctc aataacggtg
    27481 aaatcgtagc gcaaatcatg ctggttcaga aatactttgc tgatgaaggg gttcaggtca
    27541 atcttgccgt gtctcttcac gcacccaaca atgaacttcg ttcaagtatc atgaagatta
    27601 accgtgcctt tccgattgaa aaactctttg ctgctattga atactacatt gagacaacaa
    27661 accgtcgtgt aacctttgaa tatatcatgc ttaatgaagt caacgacggt gtagaacaag
    27721 ccttggaatt ggctgaattg ctcaagaaca tcaagaaatt gtcttatgta aacttgattc
    27781 cttataaccc agttagtgag catgaccaat atagccgtag tcccaaagag cgcgtgttgg
    27841 ctttctatga tacgcttaag aaaaaagggg tcaactgtgt ggttcgtcaa gagcatggta
    27901 cagatattga cgcagcttgt ggacaattgc gctctaacac aatgaaacgt gaccgccaga
    27961 aggcagtcgc agcggtaaat ccttaatgat gaagaagact tataatcata ttttggtctg
    28021 gggagtcatt ttctatagca tttgcattgt ctgtttttgc tttactcctc aagaacaatc
    28081 taccgtggga gtgggaactc caggtattca gcatcttgga cgcctggttt ttcttttgac
    28141 tcctttcaat tctctctgga aactgggcga agtgagtgac attggacaat tatgttggat
    28201 ttttttacaa aatgtcctca atatcttctt gttttttcct ctgattttcc aactccttta
    28261 tctatttcca aatttgcgga aaacaaaaaa ggtccttctt tttagttttc ttgtgagtct
    28321 tggaatcgag tgtacgcaat taatcttgga ctttttcttt gatttcaatc gcgtctttga
    28381 gattgatgat ttgtggacca atactttggg tggctatctg gcttggctcc tttataaacg
    28441 attacataaa aacaagataa ggaattaaaa tgagtatttt agaagttaaa aatctgagtc
    28501 acggttttgg tgaccgtgca atttttgaag atgtgtcctt ccgtctcctc aagggagaac
    28561 atatcggcct ggtcggtgcc aatggtgaag gaaaatcaac ctttatgagt atcgtgactg
    28621 gtaaaatgct gccagatgaa ggaaaggttg agtggtccaa atatgtgacg gctggttact
    28681 tggatcagca ctctgtcctt gctgaaagac agtcggtgcg tgatgttctc cgtacggctt
    28741 ttgatgagct tttcaaagct gaagctcgta tcaatgacct ctatatgaaa atggctgaag
    28801 acggcgcgga tgttgatgct ctcatggaag aagtaggaga acttcaagac cgtctggaga
    28861 gtcgtgattt ctataccttg gatgctaaga ttgacgaagt agcgcgtgct cttggtgtta
    28921 tggactttgg catggatacg gatgtaactt ctttgtcagg tgggcaaaga accaaggtgc
    28981 ttttggcaaa acttctcctt gaaaagcctg atatcttgct gttggacgag ccgaccaact
    29041 acttggatgc tgagcatatt gattggctca agcgctatct ccaaaactat gagaatgcct
    29101 ttgttctcat ttcgcacgat attccattcc tcaatgacgt tattaatatt gtctatcatg
    29161 tggaaaatca acagctgacg cgttactctg gtgactacta ccagttccaa gaagtttatg
    29221 ctatgaagaa atctcagcta gaggcagcct acgaacgcca gcagaaagag attgcagacc
    29281 tcaaggactt tgtggctcgt aataaagccc gtgttgcaac tcgtaatatg gctatgtctc
    29341 gtcaaaagaa attggataag atggatatta tcgaactcca aagtgagaaa ccaaaaccat
    29401 cctttgattt caaaccagct cgtacaccag ggcgctttat cttccaagcc aagaacttgc
    29461 aaattggtta cgaccgtcct cttactaagc ctttaaatct taccttcgaa cgcaatcaaa
    29521 aggttgcgat tattggtgct aatggtattg gaaaaacaac tctcttgaag agtctcttgg
    29581 gcattatctc gccaatcgct ggggaagtgg agcgtggaga ttatttagaa cttggttatt
    29641 ttgagcagga agtagaaggt ggtaatcgcc aaactcctct tgaagctgtc tggaatgcct
    29701 ttcctgccct taatcaagca gaagtccgtg cagcccttgc ccgttgtggt ttgacaacca
    29761 aacatattga aagccagatt caagtattat cagggggaga gcaagccaag gttcgtttct
    29821 gtctcttgat gaatcgtgaa aacaacgttt tagtgctgga cgagccgacc aaccatttgg
    29881 atgtggatgc aaaggatgag ctcaaacgcg ctctcaaaga atacagggga tctatcctta
    29941 tggtctgcca cgagccagac ttttatgaag gttggataga ccaaatatgg gattttaata
    30001 atttaactta agaatgagag taaaagaaat acggctcttt gtcaactgta gtgggttgaa
    30061 gtcagctaag ctcgagaaag gacaaaattc gtcctttctt ttttgatgtt cagagcgata
    30121 aaaatccttt ttttgaagtt ttcaaagttc cgaaatccaa aggcgtttcg tttgataagt
    30181 ttgatgagat tattggtcgc ttccaatttt gcgttggaat aaggtaattg aagagcgttg
    30241 acgatttttt ctttgt
//
LOCUS       DAVLTG010000022        29417 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLTG010000022 DAVLTG010000000
VERSION     DAVLTG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.022"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            357..1520
                     /locus_tag="VYN12_001056"
     CDS             357..1520
                     /locus_tag="VYN12_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1415461.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHCFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1517..2194
                     /locus_tag="VYN12_001057"
     CDS             1517..2194
                     /locus_tag="VYN12_001057"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1415462.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2184..3038
                     /locus_tag="VYN12_001058"
     CDS             2184..3038
                     /locus_tag="VYN12_001058"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1415463.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3057..4124
                     /locus_tag="VYN12_001059"
     CDS             3057..4124
                     /locus_tag="VYN12_001059"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1415464.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4134..5300
                     /gene="aroC"
                     /locus_tag="VYN12_001060"
     CDS             4134..5300
                     /gene="aroC"
                     /locus_tag="VYN12_001060"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1415465.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5310..6413
                     /locus_tag="VYN12_001061"
     CDS             5310..6413
                     /locus_tag="VYN12_001061"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1415466.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYILTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPRMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6424..6762
                     /locus_tag="VYN12_001062"
     CDS             6424..6762
                     /locus_tag="VYN12_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1415467.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6854..8137
                     /gene="aroA"
                     /locus_tag="VYN12_001063"
     CDS             6854..8137
                     /gene="aroA"
                     /locus_tag="VYN12_001063"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1415468.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8130..8606
                     /locus_tag="VYN12_001064"
     CDS             8130..8606
                     /locus_tag="VYN12_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1415469.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8603..9451
                     /gene="pheA"
                     /locus_tag="VYN12_001065"
     CDS             8603..9451
                     /gene="pheA"
                     /locus_tag="VYN12_001065"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1415470.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9448..10722
                     /gene="psr"
                     /locus_tag="VYN12_001066"
     CDS             9448..10722
                     /gene="psr"
                     /locus_tag="VYN12_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1415471.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11001..11846
                     /locus_tag="VYN12_001067"
     CDS             11001..11846
                     /locus_tag="VYN12_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1415472.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFFPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11836..12939
                     /locus_tag="VYN12_001068"
     CDS             11836..12939
                     /locus_tag="VYN12_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1415473.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12941..13927
                     /locus_tag="VYN12_001069"
     CDS             12941..13927
                     /locus_tag="VYN12_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1415474.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDARVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13943..15376
                     /locus_tag="VYN12_001070"
     CDS             13943..15376
                     /locus_tag="VYN12_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1415475.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15405..16439
                     /locus_tag="VYN12_001071"
     CDS             15405..16439
                     /locus_tag="VYN12_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1415476.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16639..17376
                     /gene="mecA"
                     /locus_tag="VYN12_001072"
     CDS             16639..17376
                     /gene="mecA"
                     /locus_tag="VYN12_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1415477.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17527..18813
                     /locus_tag="VYN12_001073"
     CDS             17527..18813
                     /locus_tag="VYN12_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1415478.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDVTIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18815..19684
                     /locus_tag="VYN12_001074"
     CDS             18815..19684
                     /locus_tag="VYN12_001074"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1415479.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19754..19834
                     /locus_tag="VYN12_001075"
                     /pseudo
     CDS             19754..19834
                     /locus_tag="VYN12_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            19979..20917
                     /gene="msrB"
                     /locus_tag="VYN12_001076"
     CDS             19979..20917
                     /gene="msrB"
                     /locus_tag="VYN12_001076"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1415480.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20975..22699
                     /locus_tag="VYN12_001077"
     CDS             20975..22699
                     /locus_tag="VYN12_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415481.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGTRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLITSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            22701..24449
                     /locus_tag="VYN12_001078"
     CDS             22701..24449
                     /locus_tag="VYN12_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415482.1"
                     /translation="MKRQTVNQTLKRLVVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24751..26010
                     /locus_tag="VYN12_001079"
     CDS             24751..26010
                     /locus_tag="VYN12_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1415483.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQHQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26086..26221
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26260..26760
                     /locus_tag="VYN12_001080"
     CDS             26260..26760
                     /locus_tag="VYN12_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1415484.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26836..27204
                     /gene="rplL"
                     /locus_tag="VYN12_001081"
     CDS             26836..27204
                     /gene="rplL"
                     /locus_tag="VYN12_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1415485.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27391..27978
                     /locus_tag="VYN12_001082"
     CDS             27391..27978
                     /locus_tag="VYN12_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1415486.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            28180..28317
                     /locus_tag="VYN12_001083"
     CDS             28180..28317
                     /locus_tag="VYN12_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1415487.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            28573..28806
                     /locus_tag="VYN12_001084"
     CDS             28573..28806
                     /locus_tag="VYN12_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1415488.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            28809..29396
                     /locus_tag="VYN12_001085"
     CDS             28809..29396
                     /locus_tag="VYN12_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1415489.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT         8685 a         5402 c         6609 g         8721 t
ORIGIN      
        1 aacaaaaggc ttttctataa aatcaaattt tccagatatc tactgaagct gatttatttt
       61 ttcatctttc ttctactacc tttgtcacta aatttgacag acacatattg ctgatacaac
      121 ctctctacct actaatctca cagttaacct gaggctagtt tcatagtttg ctatttgatt
      181 ttcgttgata aaaaaaatgc tcctccaaga cggaagagca ttttttattg tgattcttac
      241 acatttactt cctagttttg caggaagtct agtataccat tttttaaaag aagagtaaaa
      301 aagcaagggt agtttctttt ttgagaattg tctaaaagtt tgatataatg gtagttatga
      361 atagaataag agtcagcaaa agggttgaaa agaagcttgc taaggggcta gttttactag
      421 aagccagtga tcttgagaat gtcaatctta aggatcagga agtagaggtg cagggtcagg
      481 aaggaaactt tcttgggact gcctaccttt ctcagcaaaa caagggcttg ggctggtttg
      541 tcagcaaaga caaggtggcc ttcaatcaag ctttctttga aacgttgttt agaaaagcca
      601 aagaaaagag aagcgcctac tatcaagatg atttaacaac tgcctttcgt ctctttaatc
      661 aagagggaga tggctttggg ggtctgacag tggaccttta tggcgactac gccgtctttt
      721 cttggtataa ctcttatgtt tatcagattc gtcagactat atcagaagcc tttagacagg
      781 ttttccctga ggttttaggg gcttatgaga aaatccgctt taagggtttg gactatgaat
      841 ctgcccatgt ttatggtcaa gaagcacctg actttttcac tgttttagaa aatggtgtcc
      901 tgtatcaagt ctttatgaat gatggcttga tgacaggaat tttcctagac cagcatgagg
      961 ttcgcggtag tttagttgac ggcttggcta tgggtaaatc cttgctcaat atgttttcct
     1021 acacagcggc tttttcagta gctgcggcca tgggaggagc tagccagaca acttctgttg
     1081 atctagccaa acgttcacga gaattgtctc aagcgcattt tcaggcaaat gggctcagca
     1141 cagacgagca ttgttttata gtcatggatg tctttgagta tttcaaatat gccaaacgta
     1201 aaaacttgac ctacgatgtg attgtcctag atccgcctag ctttgctcgg aataaaaaac
     1261 aaactttctc tgtggccaag gattatcaca agttgatttc ccagagtctt gagattttaa
     1321 atccgggagg gattatcatt gccagtacca atgctgccaa tgtttcccgt cagaaattta
     1381 cagaacaaat tgataaaggc tttgcaggaa gaagttacca gattttaaac aaatatggtc
     1441 ttccagcaga ttttgcctat aataaaaaag atgaaagtag taattacctc aaggtgatta
     1501 gtatgaaggt tagtaaatga aattaatcgt ttcagtaatg ccaagaagtt tagaggaggc
     1561 tcaggctctg gatgccacga ggtacctgga tgccgacatc attgaatggc gtgccgacta
     1621 tctgcctaaa gaagcgattt tgcaggtagc tccagccatt tttgaaaaat tcgcaggccg
     1681 tgagttggtt ttcacgctac gaactcgctc cgaaggtgga gaaatcgacc tttctccaga
     1741 agagtatatc catctaatca aggaagttgc gcaactctat caaccagact atattgattt
     1801 tgagtactat agctacaagg atgtttttga ggaaatgctg gacttcccaa atcttgtttt
     1861 gagttaccat aatttccaag aaacacctga gaacatgatg gaaatcttgt cagagttgac
     1921 gatcctaaat ccaaaacttg ttaaggttgc ggtgatggct cacacggagc aggatgtctt
     1981 agacttgatg aactatacac gaggctttaa aaccctcaat cctgaacagg aatatgtgac
     2041 catttctatg ggtaaggtgg gcaaggtctc tcgtatcact gcggatgtga ctggttcgag
     2101 ttggtctttt gccagtctgg atgaggttag tgcccctggg cagatttctc tagctagcat
     2161 gaaaaaaatc agggagattt tggatgaagc ttgatggcta tacacgttta gctgcagttg
     2221 ttgccaatcc tattaagcat tctatttctc ccttcatcca caatagagcc tttgaggcga
     2281 cagctaccaa cggtgcttat gtggcttggg agattgaagc gagtgacttg gtagaaacag
     2341 tggccaatat tcgtcgctac cagatgtttg gcatcaatct gtccatgccc tataaggagc
     2401 aggtgattcc ttatttggat gagctgagcg atgaagcgcg cttgattggt gcggttaata
     2461 cggttgtcaa tgagaatggc aatttaattg gatataatac agatggcaag ggatttttta
     2521 agtgcttgcc ttcttttaca atttcaggta aaaagatgac cctgctgggt gcaggtggtg
     2581 cggctaaatc aatcttggca caggctattt tggatggcgt cagtcagatt tcggtctttg
     2641 ttcgttccgt ttctatggaa aaaacaagac cttacctaga caagttacag gagcagacag
     2701 gctttaaagt ggatttgtgt gctttagaat atgtttctga actgcaagca aggattgccg
     2761 agtcggattt gctagttaat gccaccagtg tgggcatgga tggccaatcc tctcctgttc
     2821 ctgaaaacat agtcttacca gaaactcttt tagttgcaga tatcatatac caaccctttg
     2881 aaacaccgtt tttgaaatgg gctagaagtc agggcaatcc agcagtcaat ggtctgggaa
     2941 tgttgctcta tcaagctgca gaagcttttc aactgtggac aggcaaggaa atgccgacag
     3001 aagagatttg gcagtcttta acagaaaaat accaataaag aaagggagac tctcctatga
     3061 aaatcagaat cgatattcct catcatcctt atgatattca gattgaaaaa ggttgtatgg
     3121 cccaggctgg tcagtggttg cgagaactct ggcaaccgca aaaggtagtc attgtgacag
     3181 ataaccatgt agcctctctc tatgcagaga aggtcaagct cagcctagaa gatgctggtt
     3241 ttcaggtagc tgtttttgat ttcttagaag gtgaagaaag aaagaattta actactgttc
     3301 agaaagtcta tgaatttcta gtcaagcaag gtctgactcg tagcgatgga atcgttgctc
     3361 ttggtggtgg cgttgttggg gacctggctg gctttgtagc ctctacctat atgcggggta
     3421 ttcactttgt tcagattccg actagtttga cagctcaggt tgattcttct atcggtggaa
     3481 agacaggcgt taacacacca tttgctaaaa atatggtggg gacctttgcc caaccagatg
     3541 gggttctgat tgatccactt gttcttgaaa ccctcggaaa aagagagttg attgaaggga
     3601 tgggtgaagt tatcaagtat ggcttgattg aggatccaga actgtgggct ctcttgacgg
     3661 gactgaatgg ttctgttgag agtattttgg aacatgcaga gaccttgatt gaacattctt
     3721 gtcaggtgaa gcgcaagatg gtggttgaag atgagttgga caatggtatt cgtctttacc
     3781 tcaattttgg ccacactatt ggccatgcca tcgaagcgac tgccggttat ggcaaggtca
     3841 tgcatggaga ggctgttgcc atgggaatgg tacagatttc caaggttgct gaggaaaaag
     3901 gcctcatgcc agctggcatt acccaatcta tcacagagat gtgtcagaaa ttcggcttgc
     3961 ctgttgacta tgaaaattgg aaagttgaca agctttatca ggctcttact catgacaaga
     4021 aagcgcgtgg taacaccttg aaattggtct tggtgccaga gcttggttca gcgaccattc
     4081 acccagtttc tctggaagag atgaaagact acttggtaaa ataaggagag tgtatgagat
     4141 atttaactgc aggagaatca cacggccccc gtctaacagc tattattgag ggaattccag
     4201 ctggacttcc attgacagct gaggatatca atgaggatct tagacgccgt cagggtggct
     4261 acggtcgtgg tggtcgtatg aagattgaga gtgaccaggt tgtctttact tcgggcgttc
     4321 gccacgggaa gacgacaggg gcgcctatta ctatggatgt catcaataag gaccaccaga
     4381 aatggctgga catcatgtct gcggaggaca ttgaagaccg ccttaaaagc aagcggaaaa
     4441 ttactcatcc tcgcccaggt catgccgatt tggttggggg gattaagtac cgttttgatg
     4501 atttgcgaaa ttctttggag cgttcatcag ctcgtgaaac caccatgcgg gtggcagttg
     4561 gtgcagtagc caaacgtctc ttggctgagc tggatatgga gattgccaac catgtcgtgg
     4621 tctttggtgg caaggaaatc gatgttcctg aaaatctgac agtcgctgaa attaagcaaa
     4681 gagctgccca gtctgaagtt tctattgtca accaagaacg agaacaggaa atcaaggact
     4741 atattgacca aatcaaacgt gatggtgata ccatcggtgg ggttgtggag acagtcgtcg
     4801 gaggcgttcc agttggtctt ggttcctatg tccaatggga tagaaaattg gatgcaagat
     4861 tggctcaagc tgttgtctct atcaatgcct ttaaaggggt ggaatttggt cttggctttg
     4921 aggctggtta tcgtaaaggc agccaagtta tggatgaaat tctctggtct aaagaagacg
     4981 gttatactcg ccgtaccaat aatctaggtg gttttgaagg tggtatgact aatgggcaac
     5041 ccatcgttgt tcgtggggtc atgaaaccca ttcctactct ttataaacct cttatgagtg
     5101 tggatatcga aacccacgaa ccttacaagg caaccgtgga gagaagtgat ccgactgctc
     5161 ttccagctgc aggaatggtc atggaagcag ttgtagcaac ggttctggcg caagaaatcc
     5221 tcgaaaaatt ctcatcagat aatcttgagg aactaaaaga agcggtagcc aaacaccgag
     5281 actatacaaa gaactattaa ggagttccta tggcaaaaac aatctatatc gcaggtcttg
     5341 ggttgattgg agcctctatg gcacttggta tcaaacgcga tcatccagat tatgaaattt
     5401 taggttataa tcgtagtcaa gcttcgagag atatcgcctt gaaagaaggc atgattgacc
     5461 gtgcaacgga tgattttgct agttttgctc ctttggcaga tgtcattatc ctcagcttgc
     5521 caatcaaaca aactattgct ttcattaagg agttggccaa tttggatttg cgagaaggcg
     5581 ttattatttc agatgctggt tcgaccaagt caaccattgt ggatgcggcg gagcagtatt
     5641 tggctggcaa gtctgttcgc tttgtcgggg cccatcccat ggctggtagt cacaagacag
     5701 gggctgcttc ggcagatgtc aatctttttg aaaatgccta ttatatcctt acaccttcaa
     5761 gcctgacaag tcaggacacg cttaaggaaa tgaaggatct gctttcaggt cttcatgctc
     5821 gttttatcga gattgatgcc aaggagcatg atcgtgtcac ttctcagatt agccattttc
     5881 ctcatatttt ggcttctagt ctcatggagc agactgcggt ctatgctcaa gagcatgaga
     5941 tggcaaggcg ctttgcggca ggtggttttc gagatatgac ccgaattgcg gaaagcgagc
     6001 caagaatgtg gacctccatt ctcttgtcca atagcgagac cattctggat agaattgagg
     6061 atttcaagga acgtttggaa gcgattggtc aggccattag taagggagat gaagagcaaa
     6121 tttggaactt ttttaaccaa gcgcgtgaac aacgccagac catggaaatc cataagcgtg
     6181 gtggtgtgga tagctcttac gacctctatg ttgacgttcc tgatgaagaa gatgtcatcc
     6241 tgcggatttt ggaactgcta cgtgggactt ccttggttaa catccacatc aacgaggaaa
     6301 atcgtgagga tattcacgga atcctacaaa tttcatttaa aaatgctcaa gacttggaaa
     6361 gagccgagca tctcataaca aaaaataccg actatacagt cgtcattaaa taaggagaag
     6421 aacatgtcaa atatttacga tagtgcaaac gaactcagtc gcggtctacg cggattacca
     6481 gaatacaagg ctgttaaagc agctaaagat gcgattgcag cagatgctga ggcaagcaaa
     6541 atctttacag aatatcttgc ctttcaagag gaaattcaaa aactagcaca gacaggtcaa
     6601 atgccagatg cgtccttcca agctaagatg gaaggctttg gtaaacagat tcaaggaaat
     6661 agcctcttgt cagaattctt taccaagcaa caacaattgg ccatttacct ttctgacatt
     6721 gaaaaaattg ttttcgaacc agtttcagaa ttgctgaaat aagaaaagaa ctatcctaaa
     6781 gtcaggaatt tttaaggaat ttctggcttt ttatgataaa ataggtaaaa gtattgcaag
     6841 tatgaggtcc agtatgaaac taaaaacaaa cattcgccat ttacatggta gtatccgcgt
     6901 cccaggtgac aagtctatca gccaccgttc cattatcttt ggaagtttgg ctgagggtga
     6961 gaccaaggtt tatgatattc tgcgaggtga agacgttctt tcgaccatgc aggtttttcg
     7021 tgaccttggt gttgaaattg aggataaaga tggggttatt accgttcaag gtgtaggcat
     7081 ggctggctta aaagcgccgc aaaatgccct taatatggga aattctggca cctcgattcg
     7141 cctgatttca ggtgtccttg ctggtgcaga tttcgaagta gagatgtttg gagatgatag
     7201 tctttccaaa cgtcctatgg accgtgtgac ccttccactg aaaaaaatgg gcgtcagcat
     7261 ctcagggcaa actgaacgag acttgcctcc ccttcgctta aaagggacga aaaacctaag
     7321 acctattcat tatgagttgc caattgcctc tgcccaagtc aagtcagcct tgatgtttgc
     7381 agccttacaa gctaaggggg agtcagttat tatcgaaaaa gagtacaccc gtaatcatac
     7441 tgaagatatg ttgcaacaat ttggtggtca tttaagtgtg gatggtaaga aaatcacagt
     7501 ccaagggcca caaaaattga caggacagaa ggtggtcgta ccaggagata tttccagtgc
     7561 agccttttgg ttagtcgcag gtttgattgc tccaaattct cgtctagtgc tgcagaatgt
     7621 ggggataaac gaaactcgca ccggtattat tgatgtcatt cgtgccatgg gtggaaaatt
     7681 ggaaataact gaaatcgatc cagtcgctaa atctgcaacc ttgattgttg agtcttctga
     7741 cttgaaagga acagagattt gtggcgcttt gattccacgt ttgattgatg aattgcctat
     7801 tattgcccta cttgcgaccc aagcccaagg tgtaacagtt atcaaggatg ctgaggagct
     7861 caaggtcaag gaaacagacc gtattcaggt tgtggcagac gccttaaata gtatgggagc
     7921 agatattact cctacggcag atgggatgat tatcaaagga aaatcagctc ttcacggtgc
     7981 tagagtcaat acgtttggtg accaccgtat cggcatgatg acagctatcg cagccctatt
     8041 ggttgcagat ggagaggtgg agcttgaccg tgcagaagcc atcaatacca gctatcctag
     8101 tttctttgat gatttggaga gcttgattca tggctaaggt gttattaggg tttatggggg
     8161 ctggaaaatc gactattgca agaggcttgg accctaatta ccttgatatg gatgctctga
     8221 ttgagaagcg cctaggtatg tccattgcga attttttcgc tgaaaaggga gaagcagcct
     8281 ttcgtcaggt agaatcagaa gtcctagctg atttattaca aagagaccaa gtcgtgtcaa
     8341 ctggaggagg agtggttatt tctcagagaa atcgtgactt actcaagact aatacagata
     8401 acatctacct gaaagcagat tttgaaaccc tctacctacg tatcgcagct gataaggaca
     8461 atcagcgacc gctttttcta aataatagca aggaagaact agtagctatt tttcaagaaa
     8521 gacaggcttg gtatgaggaa gtggctagtc gggttttgga tgtgaccaag ctaagcccag
     8581 aggaaattat agaggaacta agatgaaaat tgcttatcta ggtcccaaag gatcattttc
     8641 acaccacgtt gtgcagacag cttttcctca tgaggaattg caggcttttg ccaacattac
     8701 agatgtcatc aaggcttatg agcaaggatt agtggactat tctgtggtgc cagttgaaaa
     8761 ttctattgag ggtagtgttc atgaaacctt ggactatctt tttcatcagg ctcacatcca
     8821 agcagtagca gaaatcgttc agcctattca tcagcagttg atggtggttc caggccatac
     8881 taagattgaa aagatttttt cacatccaca ggccttggct caaggaaaga aattcatcga
     8941 tgaacaatat ccagaggctc aaatcgaggt aacagctagt acagcttatg cggcccgttt
     9001 tatttccgaa catccagatc agccctttgc agcaattgca cctagaagtt ctgctgaaga
     9061 atatggattg gaactgattg ccgaggatat tcaggaaatg gaagccaatt tcacacgttt
     9121 ctggcttcta ggagctgaaa agcctagtat tcccttgcaa gcacaaactg aaaagatgag
     9181 tttggccttg acattacctg acaaccttcc aggtgcactt tataaggccc tgtcgacctt
     9241 tgcttggcga ggaattgact tgacaaaaat tgaaagtcgt ccactcaaga cagcactggg
     9301 tgaatacttt ttcattatcg atgtggatta taccgataag gacttggtcc actttgccca
     9361 aaaagaatta gaagcgattg gaatccagta taaaattctg ggtgcctatc ctatttatcc
     9421 aatatcagac catggaaagg agagaagatg agtaaagaaa atcccttaag tcatcatgag
     9481 cagttgcgtt atgattattt gctaaaaaat attcactatc tcaatgagag agaaaaaaat
     9541 gagtttgtct atttgcaaga aaagctaact cttgctaggg gaaatagtag ctctagcttg
     9601 gaacaagaaa gagaagagca ggttgactta ccaagctatg cgaaccggag tcgctcacaa
     9661 tccaaatcac aagcactctc tttccctcca aaaaagaaaa gacggaagct ccgtcttaaa
     9721 cgaattttta tggtgatttt ttcacttttg gtctgtgtgg ctttggccat ggtattcatg
     9781 tttttgcgtg gttaccaaga tgctagcgca aagaaaactg ctgatgcccg ggcagctcaa
     9841 gtagaagtct ttaatggtca ggacactaga gatggagtta atattttaat catgggtact
     9901 gatggtcgaa tcggccagaa cagtgttgag acacgaactg actctattat ggtattaaat
     9961 gtcgggggct cagataagaa aatgaagcta gtcagtttca tgcgtgataa tttggtctat
    10021 atagatggtt atagtcaagt gattaacggt agaaaacaga cagataacaa gttaaacgta
    10081 gcctacgagt taggagaaca agaagggcaa aaaggggcag aaatggttcg ccaagtcttg
    10141 aaagataatt ttgacttgga cattaagtac tacgccttgg ttgatttcca ggcctttgcc
    10201 acagcgattg acacgctttt ccctgatggg gtgacgattg atgctcaatt ttcaacattg
    10261 aatgggcgtc ccctaacaga agctacagtc ggagatgatt tatacgctac cgagactgag
    10321 tctccaaccc aaaccattaa agtcggaaaa cagcagatga atggctcgac cctgctcaat
    10381 tatgctcgtt tccgtgatga tgatgaggcg gattacggcc gtacaaaaag acagcaacaa
    10441 gttttaacag caattttaga gcaaattaaa gatcccacta aacttttcac tggttctgaa
    10501 gctcttggaa aggtttttgc tatgacctca accaacgtac cctatacttt cctcctaaca
    10561 aacggtttat ctgttttgga tggagcaaaa aatggtattg aaaaattgac gattccagaa
    10621 ctgggtgact gggtagatgc ctatgatgtt tatggaggct tgggcttgct ggttgatcaa
    10681 aacaaatatc aaaccaagct cgctcaaatg ggcttgagat aagataatac tcaatgaaaa
    10741 tcaaagtgca aattaggaag ctagccgcag gctgctaaaa acacagtttt gaggttgtag
    10801 ataagactga cgaagtcagt tacctatacc tacggcaagg tgaagctgac gtggtttgaa
    10861 gagattttcg aagagtataa gacagaaaaa tcaaagtttg atagctattt ggatagcagt
    10921 caggctttga ttttttacag tctgcaatag attttcaccc cttgtttgtg gtataatgaa
    10981 acgatacgat agaaagaata atgaacaata tgactgattt aaaagcaatt caggctcgta
    11041 gtctggagat ggctgaatat tttgtggcct tttgtaaaga acatgatttg ctctgttatc
    11101 tctgtggcgg aggcgctatt ggtacccttc gaaacaaggg atttattcct tgggacgacg
    11161 acctagactt ttttatgcct cgtaaagatt atgagaaatt agcagaatta tggcctcgtt
    11221 atgcagatga acgttatttc ttgtcaaaga gtcacaagga ttttgttgat cgtaatcttt
    11281 ttattaccat tcgtgacaag aaaaccacct gtatcaagcc ttatcagcag gatttggatt
    11341 tgccacatgg tctggccttg gatgttttgc ctttggatta ttatccgaaa aatccagctg
    11401 agcggaaaaa acaggttcgt tgggccttga tttattcact cttttgtgcg caaactattc
    11461 cagaaaagca tggtgctctc atgaaatggg gaagtcgcat tttactgggt ttgactccaa
    11521 aatctctccg ttatcgcatc tggaaaaaag ctgagaaaga aatgactaag tatgatttgg
    11581 ctgattgtga tggcattaca gaattatgct caggtcctgg ctacatgaga aacaagtacc
    11641 caatcacatc ttttgaagac aatcttttct ttccatttga aggaacagag atgcctattc
    11701 caatcggcta tgatgtctat ctcagaactg cttttgggga ttatatgacg cctccaccag
    11761 cagacaagca ggtaccgcat catgatgctg tcatcgctga tatggataag tcttatacag
    11821 aatacaaggg agaatatggt ggctaagaaa aaaatcttat tttttatgtg gtctttttct
    11881 cttggaggtg gtgcagagaa gattctatca accattgttt caaatctgga tccagaaaag
    11941 tatgatattg atattcttga aatggagcac tttgacaagg gatatgaatc tgttccaaag
    12001 catgtacgca ttttaaaatc ccttcaagat tatcgccaaa ccagatggtt acgagctttt
    12061 ttgtggagaa tgagaattta ttttccaaga ctggctcgtc gtttgcttgt aaaagatgat
    12121 tatgatgttg aagtttcttt taccattatg aatccaccac tgttgttctc taaaagaaga
    12181 gaagtcaaga agatatcttg gattcatgga agtattgaag aacttcttaa ggatagctct
    12241 aaaagagaat cacatagaag ccagttggat gctgcgaata caattgtagg gatttcaaaa
    12301 aagaccagca attctatcaa ggaagtttat ccagattatg cttctaaatt acagacaatc
    12361 tacaatggat atgattttca gactattcta gaaaaatctc aagagaagat cgatatcgag
    12421 attgctcctc aaagtatctg tactatcgga cggatcgagg aaaataaggg ttctgaccgt
    12481 gtagtggaag tgatacgatt attacaccaa gagggaaaaa actatcatct ctattttatc
    12541 ggggctggtg atatggaaga ggaactgaaa aaacgagtca aagagtatgg gattgaggac
    12601 tatgtacatt tccttggtta tcaaaaaaat ccttatcagt atttatctca gacgaaagtt
    12661 ctcttgtcta tgtctaaaca agaaggtttt cctggagtgt atgtggaggc cttgagtctg
    12721 ggactccctt ttatctctac ggacgttgga ggggctgagg aattatccca agaaggacga
    12781 tttggacaaa tcattgagag caatcaagag gcagctcagg cgattactaa ttacatgact
    12841 tctgcctcaa actttgatgt cgatgaggct agccaattca ttcaacaatt tacaattaca
    12901 aaacaaatcg aacaagtaga aaaactatta gaggagtagc atggaaactg cattaattag
    12961 tgtgattgtg ccagtctata atgtggcgca gtacctagaa aaatcgatag cttccattca
    13021 gaagcagacc tatcaaaatc tggaaattat tcttgttgat gatggtgcaa cagatgaaag
    13081 tggtcgcttg tgtgattcaa tcgctgaaca agatgccagg gtgtcagtgc ttcataaaaa
    13141 gaacgaagga ttgtcgcaag cacgaaatga tgggatgaag caggctcacg gggattatct
    13201 gatttttatt gactcagatg attatatcca tccagaaatg attcagagct tatatgagca
    13261 attagttcaa gaagatgcgg atgtttcgag ctgtggtgtc atgaatgtct atgctaatga
    13321 tgaaagccca cagtcagcca atcaggatga ctattttgtc tgtgattctc aaacatttct
    13381 aaaggaatac ctcataggtg aaaaaatacc tgggacgatt tgcaataagc taatcaagag
    13441 acagattgca actgacctat cctttcctaa ggggttgatt tacgaagatg cctattacca
    13501 ttttgattta atcaagttgg ccaagaagta tgtggttaat actaaaccct attattacta
    13561 tttccataga ggggatagta ttacgaccaa accctatgca gagaaggatt tagcctatat
    13621 tgatatctac caaaagtttt ataatgaagt tgtgaaaaac tatcctgact tgaaagaggt
    13681 cgcttttttc agattggcct atgcccactt ctttattctg gataagatgt tgctagatga
    13741 tcagtataaa cagtttgaag cctattctca gattcatcgt tttttaaaag gccatgcctt
    13801 tgctatttct aggaatccaa ttttccgtaa ggggagaaga attagtgctt tggctctatt
    13861 cataaatatt tccttatatc gattcttatt actgaaaaat attgaaaaat ctaaaaaatt
    13921 acattagaac gggggtgacc aagtgattga tgggaaacga ttattattta gtttgaccat
    13981 agtcagttat gccttgacgc tagtaagtgg aattgtgtat ctgtttaata ataataatgt
    14041 tagcttactt tctactttat tgttcttgtt ggttagtagc ttaattgctt gttggaatga
    14101 tatcaagtat tacttaatcc attttatttt ctatttaacc atttttgtat ttctggtatc
    14161 aagaccgacc attgattatt ttagggatgg tgctttggat acctatcatc caatagccta
    14221 tcgttttgcc tttatagttg tcatggtttc gattctgggc ttgaccacag gaggcattct
    14281 ggctcgctac ttcatagcta ggaagaaaat aaaagtagca aatataggaa attctctaaa
    14341 agaggtttat atcaagcggt tacgctttgt atcactagga gtttttcttc taacctatcc
    14401 tttctatttc attcgattat ttgaacggct cttgtatcgt ttgcagactt cctactatgc
    14461 ctactatgca aattttgaaa gtaaactgcc ttattttacc tacattttgt ctacctttac
    14521 ggtctatgca atgtgtatgt atctggcaac caagccaaag aaattgcagg ccacagcagt
    14581 gcttgtctcc tttattgcag ctaatactat tcatttggca attgggacac gaaatccctt
    14641 tattttaagt attttatttg cttttgttta ttactttatg cgggagcaaa ctgaaaaagg
    14701 aaaatggatt gggtttaaag aaaagttagc gatttttgta ggttctccta ttctcatgtt
    14761 agcgatggga gtactcaatt atgtacggga taatgtccaa gtttcccata caggtttctg
    14821 ggatatctta cttgacttta tctataaaca agggactagt tttggtgttc tggctcgagg
    14881 ttttctattt aacagtagcc tcccttaccg agatttccgt aattttactt ttggtcctgt
    14941 tcttgattat tttgcaaggg ggagtttggg agctattttc ggaggaaaag cctttgaaca
    15001 tacaaccaat agtgtggaac tagctattga tagtaatagt tatgcccaca atctatccta
    15061 tcttgtcttg aacaaggaat acctgaaagg gcatggtatc ggaagtagtt atatcatgga
    15121 gttgtatacc gactatggta tgattggagt ctttctgctt agtttcttac tcggcgtatt
    15181 atttatagcc atgctgcaag tagcctatcg ctcaaggaca atcctatttg ctttatccct
    15241 actcatcttg aataatctat tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa
    15301 tttatttaca atgcaattct ggggaattgt tcttgtgatt atatttgtag caaaaatgct
    15361 tacaaaggaa aactagtatt tactaaacaa aggagaaaaa aatcatgttt gaacattatt
    15421 cagtagctga tttgtttgca aatctttata aaaaacgaaa agcaaatatt ttagctctca
    15481 tcgctttatt tgctctcatt gctgtaccat ttacaattaa agcagttagg aataaaaaca
    15541 ctgtcaaaga tacaacaagt tattcaactt atcttatcta taaaatcact cctccagaag
    15601 agtcggccaa aacgattttg aatcatcaaa ttggtggtta tagtgatttt tatgggaaat
    15661 tgattgatgg taatttgaat ggagcttatc ttttcaatga tgtagaaccc agtgagttga
    15721 aaaaaattgc cagtgaatta gacacgacag aaacaacctt gaaaaattca acgaatgact
    15781 attggtggaa aaaattgacc gtctactata tgattgacga tgcaggggtt ggtgtgaaaa
    15841 ttttgacatc aagtaaagat gccaatgact tgttagagaa aaaaattgat gggttgattg
    15901 agaaatttaa acatgcttat gcaaatgtga aaattgaaaa actggaaacc atcaactcta
    15961 aagaattgaa cgcaaatggt gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc
    16021 gtttagttgt tattggagtg gtttgtgtga ttttggttgt gatgggaaat gtgttagttt
    16081 atctctttaa tccaacaatc aatagagtag gtgatttttc tcagtatcaa attgattttg
    16141 taacagagat tacaacaatt gctaacctag cagatgtttt gtcatacaaa aatactggac
    16201 aggaattgac catcgttagc tcaaataaag ctatcctaga taaattgaaa cagagtcaag
    16261 aagctttaaa aggaatgcat tttgtagatt tacaggatgt atcatctctt ttggaaagag
    16321 atacagtcct tcttgttgaa gagtacggag tgactcgtta taagaaattt gagcaaagtc
    16381 ttcaaattct cagaaactta aatcgttcta tcctcggtgt agcaaccttt aaattataag
    16441 tattctgatg tataaggtct tcaaaatcgg ctcttagccg attttgaagg ctttttctat
    16501 ctgtctgcag aaattttctt ttggagtctc ctatagaaag accctaggga aaatctatcc
    16561 gtatagagga gccttctttt gataaaatcg taaaaatcta gtataataga tagaactgaa
    16621 agtatgaggt tactagcaat gaaaatgaaa caaattagtg atacaacttt aaaaatcacg
    16681 atgtctttag aggatttgat ggatcgtgga atggagattg ctgactttct cgttcctcaa
    16741 gaaaaaacag aagagttctt ttatgctatc ttggatgagc tagagatgcc tgatagcttt
    16801 ctggatacag gcatgttgag cttccgtgtg actccaaaac ctgataaggt agatgtcttt
    16861 gtgaccaagt caaagattga ccaaaatcta gattttgaag acttatcgga tttgccagat
    16921 atggaagaat tggctcaaat gtctccagat gaatttatca aaaccctgga aaaaagcatc
    16981 gcagacaaaa ccaaggatga tatcgaagcc attcaatctc ttgagcaagt tgaagccaag
    17041 gaagaagagc aagagcaagc tgaacaagaa gctgagagta agaaagaacc ttacatctac
    17101 tacatccttt cttttgctaa gttggctgac ttggtagctt ttgccaagac agtgactttt
    17161 gaaatggaaa cttctgaact ctacaaaatg aacgagcgct attatttgac cattttagtg
    17221 gatattgaaa atcatccaag cccatatcca gcttggctgt tggcccgtat gcgcgagttt
    17281 gcagacgata gtgatatcag tcgctcagtc ttacaagagt atggtcaagt cttgatgagt
    17341 cacgatgcag tgctcaatct gcaaaaaatc ggctaatcct ttctggaaag ctattttcag
    17401 attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa tagtgattta
    17461 ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa tttcgaggag
    17521 ataaagatga cagttaaaat tgctttactg ggatttggta ccgttgcaag tggtgtgcct
    17581 ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga tatcaaagtt
    17641 gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc agggaatgac
    17701 tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatgttac tatcgtagtg
    17761 gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt ggaagctgga
    17821 aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga attgctagaa
    17881 atcgctcaag ctaacaaggt agcactttac tacgaagcag cagttgctgg tgggattcca
    17941 attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt gcttggagta
    18001 gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg gtcttacgat
    18061 gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac gaatgacgta
    18121 gatgggattg atgcagccta caagatggtt attttgagcc aatttgcctt tggcatgaag
    18181 attgcctttg atgatgtagc ccacaaggga atccgcaata tcacaccaga agacgtagct
    18241 gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga aacttcttca
    18301 ggtattgctg cagaagtgac tccaaccttc ctacctaaag cgcacccact tgctagtgtg
    18361 aatggcgtaa tgaacgctgt ctttgtagaa tctatcggta ttggtgagtc tatgtactac
    18421 ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat tgtccgtatc
    18481 gttcgtcgtt tgaatgatgg taccattggc aaagacttca acgaatatag ccgtgacttg
    18541 gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt ggctctagac
    18601 tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat ttcctttaag
    18661 caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat cacacacaag
    18721 attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc agaattcgac
    18781 ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac ctgcaaccag
    18841 tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt atcttcaaat
    18901 tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca aatggattcc
    18961 acatgatgag cgtaatctct tgctcaaaat cgctttacaa attgtaccag acttgcaacc
    19021 aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt cttccagctc
    19081 ggttattgtt gctgggattg aactagccaa ccaactgggt caactcaact tatcagacca
    19141 tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg ctccagccat
    19201 ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta tcgtagcaga
    19261 ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta ctcgcgacag
    19321 ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gttgctgcaa gttctatcgc
    19381 caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc aagcaatcga
    19441 gggagacctc ttccatgagc gttatcgtca ggacttggta agagaatttg cgatgattaa
    19501 gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg ggccgacagt
    19561 tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg aaaagcaacc
    19621 tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg tagaagcaaa
    19681 ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata tcctttttgt
    19741 gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
    19801 ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagctcaa aacagtgttt
    19861 tgaggttgca gatagaactg acgaagtcag taacatatat acggtaaggt gacgctgacg
    19921 tggtttgaag agattttcga agagtattag ttaaaaacgt gataaaggag aaataaaaat
    19981 ggcagaaatt tatctagcag gtggttgttt ttggggccta gaggaatatt tttcacgcat
    20041 ttctggagtg ctagaaacca gtgttggcta cgctaatggt caagtcgaaa cgaccaatta
    20101 ccagttgctc aaggaaacag accatgcaga aacggtccaa gtgatttacg atgagaagga
    20161 agtgtcactc agagagattt tactttatta tttccgagtt atcgatcctc tatctatcaa
    20221 tcaacaaggg aatgaccgtg gtcgccaata tcgaactggg atttattatc aggatgaagc
    20281 agatttgcca gctatctaca cagtggtgca ggagcaggaa cgcatgctgg gtcgaaagat
    20341 tgcagtagaa gtggagcaat tacgccacta cattctggct gaagactacc accaagacta
    20401 tctcaggaag aatccttcag gttactgtca tatcgatgtg accgatgctg ataagccatt
    20461 gattgatgca gcaaactatg aaaagcctag tcaagaggtg ttgaaggcca gtctatctga
    20521 agagtcttat cgtgtcacac aagaagctgc tacagaggct ccatttacca atgcctatga
    20581 ccaaaccttt gaagagggga tttatgtaga tattacgaca ggtgagccac tcttttttgc
    20641 caaggataag tttgcttcag gttgtggttg gccaagtttt agccgtccga tttccaaaga
    20701 gttgattcat tattacaagg atctgagcca tggaatggag cgaattgaag ttcgttctcg
    20761 ttcaggcagt gctcacttgg gtcatgtttt cacagatgga ccgcgggagt taggcggcct
    20821 ccgttactgt atcaattctg cttctttacg ctttgtggcc aaggatgaga tggaaaaagc
    20881 aggatatggc tatctattgc cttacttaaa caaataaaac agagagtggg gcttcccact
    20941 ttcttcattt ctagaatatg aatagaaggg atttatgaaa cacctattat cttacttcaa
    21001 accctacatc aaggaatcaa ttttagcccc cttgttcaag ctgttagaag ctgtttttga
    21061 gctcttggtt cccatggtga ttgctgggat tgttgaccaa tctttacctc agggagatca
    21121 aggtcatctc tggatgcaga ttggtctgct ccttatcttt gcagtaattg gcgttttagt
    21181 ggccttgata gctcaatttt actcagcaaa ggcagcagta ggttttgcta aggaattgac
    21241 aaacgatctt tatcgtcata ttctttcctt gcccaaggac agcagagacc gtctgacaac
    21301 ttctagtttg gtcactcgct tgacttcgga tacctaccag attcagactg gtatcaatca
    21361 attcctgcgt ctctttttac gagcgcccat tatcgttttt ggtgccattt ttatggctta
    21421 tcgaatctca gctgagttga ctttctggtt cttagtcatg gttgccattt tgaccattgt
    21481 cattgtaggg ttatctcgat tggtcaatcc tctctacagt agtctcagaa agaaaacgga
    21541 ccaactggtt caggaaacgc gccagcaatt gcaagggacg cgggttattc gtgcttttgg
    21601 tcaagaaaaa cgagagttac agatttttca aacccttaac caagtttatg ctagattaca
    21661 agaaaagaca ggtttctggt ctagtttatt aacacctctg acctatctga ttgtcaatgg
    21721 aactcttctc gttattatct ggcaaggcta tatttcaatt caaggaggag tgctcagtca
    21781 aggtgctctc attgctctta tcaattacct cttacagatt ttggtggaat tggtcaagct
    21841 tgccatgctg atcacttccc tcaaccagtc ctacatctca gccaagagaa tcgaggaggt
    21901 ctttgcggaa tctcccgaaa acatccattc agaattagaa caaaagcaag ttaccagtga
    21961 tcgggtttta caagtccaag aattgacctt tacctatcct gatgcggccc agccttctct
    22021 gagagacatt tcctttgata tgactcaagg acaaatcctt ggtatcattg gggggactgg
    22081 ttctggtaaa tcaagcttgg tgcaactctt acttggactt tatccagtag acaaggggaa
    22141 cattgacctt tatcaaaatg gacgtagtcc tcttaatttg gagcagtggc ggtcttggat
    22201 tgcctatgta cctcaaaagg tcgaactctt taaaggaacc attcgttcca acttgactct
    22261 aggtttcaat caagaagtat ctgaccagga actctggcag gccttggaga ttgcgcaagc
    22321 taaggatttt gtcagtgaaa aggaaggact cttggatgct ctagttgagg caggggggcg
    22381 aaatttctca ggtggacaaa aacaaagatt gtctatcgcc cgagcagtct tgcgccaagc
    22441 tccgtttctc atcctagatg atgcaacctc ggcactggat accattacag agtccaagct
    22501 cttgaaagct attagagaaa attttccaaa cacgagctta attttgatct ctcaacgaac
    22561 ctcaacttta cagatggcgg accagattct cctcttggaa aaaggtgagt tgctagctgt
    22621 tggcaagcac gatgacttga tgaaatccag ccaagtctat tgtgaaatca atgcatccca
    22681 acatggaaag gaggactaga atgaaacgac aaactgtaaa ccagacgctc aaacgtttag
    22741 tcgtagattt agcaagccat cctttcctcc ttttcctagc ctttctagga actattgctc
    22801 aagttggctt atcaatttac ctacctattc tgattgggca ggtcattgac caagtcctag
    22861 tggctggttc atcaccagtt ttttggcaga tttttctcca gatgctcttg gtggtaatag
    22921 gaaatactct ggtacaatgg gccaatcctc tcctctataa tcgtctaatc ttctcttata
    22981 ccagagattt acgggagcga atcatccata agctccatcg tttaccgatt gcctttgtag
    23041 ataggcaagg tagtggagag atggttagtc gtgtaaccac ggacatcgaa cagttggcag
    23101 ctggcttgac catgattttt aaccaatttt tcattggtgt tttgatgatt ttggtcagta
    23161 ttctagccat gctccaaatt catctcctca tgactctctt agtcttgctg ttgacgccac
    23221 tgtccatggt gatttcacgc tttattgcca agaaatccta tcatctcttc cagaagcaaa
    23281 cagagacgag gggaattcag actcagttga ttgaagaatc gcttagtcag cagactataa
    23341 tccagtcctt caatgctcaa acagaattta tccaaagatt gcgtgaggct catgacaact
    23401 actcaggcta ttctcagtca gccatctttt attcttcaac ggtcaatcct tcgactcgct
    23461 ttgtaaatgc actcatttat gcccttttag ctggagtagg agcttatcgt atcatgatgg
    23521 gttcagcctt gaccgtcggt cgtttagtga cttttttgaa ctatgttcag caatacacca
    23581 agccctttaa cgatatttct tcagtgctag ctgagttgca aagtgctctg gcttgcgtag
    23641 agcgtatcta tggagtctta gatagccctg aagtggctga aacaggtaag gaagtcttga
    23701 ccagtgacca agttaaggga gctatttcct ttaaacatgt ctcttttggc taccatcctg
    23761 aaaaaatttt gattaaggac ttgtctatcg atattccagc tggtagtaag atagccatcg
    23821 ttggtccgac aggtgctgga aaatcaactc ttatcaatct ccttatgcgt ttttatccca
    23881 ttagctcggg agatatcttg ctggatgggc aatccattta tgattataca cgagcatcat
    23941 tgagacagca gtttggcatg gtgcttcaag aaacctggct cacacaaggg accattcatg
    24001 ataatattgc ctttggcaat cctgaagcca gtcgagagca agtaattgct gctgccaaag
    24061 cagctaatgc agactttttc atccaacagt tgccacaggg atacgatacc aagttggaaa
    24121 atgctggaga atctctctct gtcggccaag ctcagctctt gaccatagcc cgagtctttc
    24181 tggctattcc aaagattctt atcttagacg aggcaacttc ttccattgat acacggacag
    24241 aagtgctggt acaggatgcc tttgcaaaac tcatgaaggg ccgcacaagt ttcatcattg
    24301 ctcaccgttt gtcaaccatt caggatgcgg atttaattct tgtcttagta gatggtgata
    24361 ttgttgaata tggtaaccat caagaactca tggatagaaa gggtaagtat taccaaatgc
    24421 aaaaagctgc ggcttttagt tctgaataag ccattctctt ttgaaagttt atggacgaaa
    24481 aaagttgcct tcgagtgact tttttgttac aatagctaga aaaattgttt actgtaatac
    24541 tcaatgaaaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa acactgtttt
    24601 gaggttgcag atagaactga cgaagtcagc tcaaaaaact gttttgaggt tgcagataga
    24661 actgacgaag tcagtaacca cacctacggc aaagtgaatt tgaagtggtt tgaagagagt
    24721 acaacttgtc ttttagaaaa ggagcctata atgaaagtct ttcagcatgt aaatatcgtg
    24781 acttgtgatc aagatttcca tgtttatctt gatggaatct tagcagtcaa ggattctcaa
    24841 atcgtctatg tcggtcaaga taagccagcg tttttagagc aagctgagca gattatagac
    24901 tatcagggag cttggattat gcctggtttg gtcaattgtc acacccattc tgcaatgaca
    24961 ggcctgagag ggatccgaga tgacagcaat ctccatgaat ggctcaatga ctatatctgg
    25021 ccagcagaat ctgagtttac tcccgacatg actaccaatg cggtcaaaga agccctaaca
    25081 gagatgctcc agtcaggaac aacaaccttt aacgatatgt ataatcccaa tggtgtggat
    25141 atccagcaaa tttatcaggt ggtgaaaact tccaagatgc gttgttattt ttctccgact
    25201 ctcttttctt cagagacaga aacaactgct gagactataa gcagaactcg atccatcata
    25261 gacgaaatct taaaatataa aaatccaaat ttcaaggtta tggtagcacc tcattctccg
    25321 tatagctgca gtagagactt gctggaagcg agtttggaaa tggcaaaaga gctaaatatt
    25381 ccgctccatg tccatgtggc ggagaccaag gaggagtcag gaattatcct caaacgatac
    25441 ggcaaacgcc cccttgcttt tcttgaagaa ctgggttatt tagatcatcc gtccgtcttt
    25501 gctcacgggg tcgaattaaa cgagagagaa attgaacgct tggcatcttc tcaagtggct
    25561 atcgcccaca atcctatcag taacctcaaa ctggcatcag gaattgctcc aattatccag
    25621 ctccaaaaag cgggagtagc agtcggaatt gcgactgact cggttgcttc caataacaat
    25681 ctagatatgt ttgaggaagg aaggactgca gctcttcttc agaagatgaa aagtggggat
    25741 gccagccagt ttccaatcga aacagctctc aaggtactga caatcgaagg ggctaaggtc
    25801 cttggaatgg aaaatcagat aggaagtctg gaagtcggca agcaagcaga ttttctggtc
    25861 attcaaccac aagggaaaat tcatctccaa catcaggaaa atatgctgtc tcacctggtt
    25921 tatgcagtta aatctagtga tgtagatgat gtttatatcg ccggagaaca ggttgttaag
    25981 caaggtcaag tcctgacagt agaactttaa aagaaaaatt acgaaaaatt ttaaaaaaag
    26041 tttgcaaaaa tcttgcattc tttttttgac tatgctatac ttatatacgg tttaaaaaaa
    26101 ctgcctaaga cagtagggga gctcgactca taaatatcct accgaggaca aaacgtatca
    26161 tgtaaaaaga agcgtattgt actttcgtgt ctaggtttgg gcgcgttttt ctttttgaaa
    26221 aattccccaa gcaaaataat tacggaggtg aacacactaa tgagtgaagc aattattgct
    26281 aaaaaagcgg aactagttga cgtagtagct gaaaaaatga aagctgctgc atctatcgtc
    26341 gttgtagacg ctcgtggttt gacagttgag caagatacag ttcttcgtcg tgagcttcgt
    26401 ggaagcgaag ttgagtataa agttattaaa aactcaatct tgcgtcgtgc agctgaaaaa
    26461 gctggtcttg aagatcttgc atctgtattt gttggaccat ctgcagtagc attttctaat
    26521 gaagatgtta tcgcaccagc gaaaatcttg aacgactttt ctaaaaacgc tgaagcactt
    26581 gaaattaaag gtggtgcaat cgaaggcgct gtcgcatcta aagaagagat tcttgcactt
    26641 gcaactcttc caaaccgcga aggacttctt tctatgctcc tttctgtact tcaagcgcca
    26701 gtgcgcaacg ttgctcttgc agtcaaagcg gttgcagaaa gcaaagaaga cgcggcttaa
    26761 tcttaagcta catagcgtag cctagctacg aaaaaaacta ttataaaatt taaaacttat
    26821 ttggaggaaa taacaatggc attgaacatt gaaaacatta ttgctgaaat taaagaagct
    26881 tcaatccttg aattgaacga ccttgtaaaa gctatcgaag aagaatttgg tgtaactgca
    26941 gctgctcctg tagctgttgc tgcagctgat gctgctgatg ctggtgctgc taaagattca
    27001 ttcgacgttg aattgacatc tgcaggcgac aaaaaagttg gtgttatcaa agttgtacgt
    27061 gaaatcactg gtcttggtct taaagaagct aaagaacttg ttgacggtgc accagcactt
    27121 gttaaagaag gcgttgcaac tgcagaagct gaagaaatca aagctaaatt ggaagaagct
    27181 ggagcttcag ttactcttaa ataatagagt atcgcaattt gattgcggaa tccctattta
    27241 ccagtctttg agagcgataa gcgattgata gaaactgata aattgatttg gtttcctgcc
    27301 aaaaattctt tggcaggatt tttgttttaa taaactttcg ggggtagaca ctagattgtc
    27361 tacccctttt tttgtgtttc ggaggtaact atgaaaagaa taattccagt ttatatattc
    27421 caacaagtaa atgtcctatt ggtatctcta tacttattga aatttctttg tatcggtgag
    27481 ttaactatac tacagattct ctatggttcg tcactcattt cttttttatg gatgtatggc
    27541 caacgcaaac aagctcataa ggtaaatatg aaatctagga tgaaatggct tggtattgga
    27601 ttcgttagcc tactgattat aagtctatgt tttagcctaa tccatgcgca agaaagcacg
    27661 aatcaagcaa acttaattgg acttcaacat caagttcctt ggttttcatt tttattgttt
    27721 ttaatcaatg cgagtatggt tgaagaattt ctgtatagag aaattttatg gaacttggtt
    27781 agaaaattag atattcgagt tgctttgaca agtgttttat ttgccttagc acatcatcca
    27841 ggaaccatta tagcttggtg tttgtatgta tcgctgggga tgtttttagg gcttgtacgc
    27901 tacaaattgg acttatgggg cagtatgggg ctacatttgg tgtggagcct actagtttat
    27961 agtttgctgc ttttttaaaa taggtaacct gatttttagg taacttctaa aactaacttc
    28021 cagttttggg agagagatgg aagttacttt gaaaagttac ggaaacatta ttttctacgt
    28081 gacaacattg tatcattgct tgcattttac tgctggagag agtataatga aggtggataa
    28141 agcacttaat cccaaaaatt taaataggag gagttagcta tggcagaaga agtattaaat
    28201 cttcaattag tatctgttca agttgacgaa acagatgaag ttgatggaat gcgatttagt
    28261 acattcagta caaaccgttg cggtaactgg agtgctttta gttgggaaaa ttgttaattc
    28321 atttaaattg taaactttag agattctctg gagttatgga tgtcgttcca atatgtgcac
    28381 gttggaatgt tagtgcttat atgggggaac agaatcctct cttgattgaa gacaagctag
    28441 tcattaggct ggtttgtctt tttgtcaact gtagtgggtt gatataatag tattagtgag
    28501 tgggataaaa gtttcattta gtttattcag tacaaattta acgggtcaag atttaactaa
    28561 aggagaagta atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga
    28621 aatatcagct ggattgagtt aaccagaaaa atgtttgcgg gagagtttca ctatccaagt
    28681 gaattgaatc gtttatatca aaagattcgc cactacaaga tggaacaacg aatgcctcaa
    28741 agtccatggg tagaaaggat tgtgcagata ttagatttag attatgaaga tttatttcgg
    28801 aggtaactat gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg
    28861 tatctctata cttattgaaa tttctttgta tcggtgagtt aactatacta caggttctct
    28921 atggtgcgtc tcttttttct tttttatgga tgtatggtca acgaaaacaa gtggtcaagg
    28981 tcaatatgaa aactaggatg aaatgccttg gtattggact agctagtcta ctgattataa
    29041 gtctatgttt tagcctgatt catgctcaag gaagcacgaa tcaaacaaat ttaattggcc
    29101 ttcaacatca agttccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg
    29161 aagaatttct gtatcgtgaa attttatgga acttggttag aaaattagat attcgagttg
    29221 ctttgacaag tgttttattt gccttagtac atcatccagg aaccattcta gcttggtgtc
    29281 tgtacgtttc acttggaatg tttttaggta tggtgcgcta taaatctgac ttatggggaa
    29341 gtatggggtt acatttggtg tggaactttt tagtttatag tttgctgctt ttttaaaata
    29401 ggtgacctga tttatct
//
LOCUS       DAVLTG010000023        26667 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLTG010000023 DAVLTG010000000
VERSION     DAVLTG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.023"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..221
                     /locus_tag="VYN12_001086"
     CDS             <1..221
                     /locus_tag="VYN12_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415490.1"
                     /translation="SQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(418..1338)
                     /gene="cysK"
                     /locus_tag="VYN12_001087"
     CDS             complement(418..1338)
                     /gene="cysK"
                     /locus_tag="VYN12_001087"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1415491.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1623..2258)
                     /locus_tag="VYN12_001088"
     CDS             complement(1623..2258)
                     /locus_tag="VYN12_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1415492.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLRDVEVPVNLV"
     gene            2314..3612
                     /locus_tag="VYN12_001089"
     CDS             2314..3612
                     /locus_tag="VYN12_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1415493.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3609..4271
                     /locus_tag="VYN12_001090"
     CDS             3609..4271
                     /locus_tag="VYN12_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1415494.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4351..4899
                     /gene="raiA"
                     /locus_tag="VYN12_001091"
     CDS             4351..4899
                     /gene="raiA"
                     /locus_tag="VYN12_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1415495.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5035..7008
                     /locus_tag="VYN12_001092"
     CDS             5035..7008
                     /locus_tag="VYN12_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1415496.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7005..7457
                     /gene="rplI"
                     /locus_tag="VYN12_001093"
     CDS             7005..7457
                     /gene="rplI"
                     /locus_tag="VYN12_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1415497.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7501..8853
                     /gene="dnaB"
                     /locus_tag="VYN12_001094"
     CDS             7501..8853
                     /gene="dnaB"
                     /locus_tag="VYN12_001094"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1415498.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8855..9121
                     /locus_tag="VYN12_001095"
     CDS             8855..9121
                     /locus_tag="VYN12_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415499.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9210..10556
                     /gene="cbpD"
                     /locus_tag="VYN12_001096"
     CDS             9210..10556
                     /gene="cbpD"
                     /locus_tag="VYN12_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1415500.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10639..10741
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10812..11102
                     /locus_tag="VYN12_001097"
     CDS             10812..11102
                     /locus_tag="VYN12_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1415501.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11065..11823
                     /locus_tag="VYN12_001098"
     CDS             11065..11823
                     /locus_tag="VYN12_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415502.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11861..12868
                     /locus_tag="VYN12_001099"
     CDS             11861..12868
                     /locus_tag="VYN12_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1415503.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12868..13596
                     /locus_tag="VYN12_001100"
     CDS             12868..13596
                     /locus_tag="VYN12_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415504.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVAEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13715..14173
                     /locus_tag="VYN12_001101"
     CDS             13715..14173
                     /locus_tag="VYN12_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1415505.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            14175..16607
                     /locus_tag="VYN12_001102"
     CDS             14175..16607
                     /locus_tag="VYN12_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1415506.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMSKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17249..17902
                     /gene="rr06"
                     /locus_tag="VYN12_001103"
     CDS             17249..17902
                     /gene="rr06"
                     /locus_tag="VYN12_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1415507.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17899..19230
                     /gene="hk06"
                     /locus_tag="VYN12_001104"
     CDS             17899..19230
                     /gene="hk06"
                     /locus_tag="VYN12_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1415508.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19313..19840
                     /locus_tag="VYN12_001105"
     CDS             19313..19840
                     /locus_tag="VYN12_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1415509.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19916..21475
                     /gene="pspC"
                     /locus_tag="VYN12_001106"
     CDS             19916..21475
                     /gene="pspC"
                     /locus_tag="VYN12_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1415510.1"
                     /translation="MFASKNERKVHYSIRKFSIGVASVAVASLFLGGVAHAEGVRIGN
                     NSTVTSSGDEVESHLQSILKDVNKNLKKVQHTQNVGLLTKLSEIKRKYLYELKVNGLE
                     EKSKAELTSKTKKELTAAFEQFKKDTLSTELEKKVAEAQKKVEEAEKKAKDQKEEDRR
                     NYPTNTYKTLELEIAESDVKVKEAELELVKEEVNEPRNEEKVKQAKAEVESKKAEATR
                     LEKIKTDRKKAEEAKRKAAEEDKVKEKPAPAPQPAPAPQPEKPAEETPAPAPKPEKPT
                     EQPKAEKPDDQQAEEDYARRSEEEYNRLTQQQPPKPEQPAPAPKIGWKQENGMWYFYN
                     TDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNSNGAMVTGWLQNNGSW
                     YYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDS
                     YRVNANGEWVN"
     gene            complement(21682..22260)
                     /locus_tag="VYN12_001107"
                     /pseudo
     CDS             complement(21682..22260)
                     /locus_tag="VYN12_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            22338..23147
                     /locus_tag="VYN12_001108"
     CDS             22338..23147
                     /locus_tag="VYN12_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1415511.1"
                     /translation="MGWQEWLDQMLAEISYDENQQELIFFVGEADYQQELSKRGFGTV
                     LPERKFGISVTMIRENPSKYWKYIAQPFRRQFTKKVLIMGSASNGKTTLAKDLARYYD
                     APVSLEYAREYQIKNNVRDDELTPKDYYYLLLGQYDQTSKLIDSNANRGLVIADTNSL
                     VTKGYYDYYMETENQVDLSGETFDNLFVSILAKEKWDLILFVQPVGSYVNDGFRDMTM
                     AEEHIRYSFSQHLDQMRERYLTTIPLVYLAEDYLGNYEAAKVTIDAIYQAD"
     gene            23157..23883
                     /locus_tag="VYN12_001109"
                     /pseudo
     CDS             23157..23883
                     /locus_tag="VYN12_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736880.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            23892..24530
                     /locus_tag="VYN12_001110"
     CDS             23892..24530
                     /locus_tag="VYN12_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1415512.1"
                     /translation="MVAYCFVEGKIKLLLIRRKAHPYQNYLALVGGFMDKGEDAAHAY
                     QREVKEEVNLDLPLEKIEQLMTVSTPGRDPRGWTVTIAYLVYLPSRALELVQASDDAK
                     DVVFVDVDFQTGKCYLEGVELDEQALAFDHYAIIQKSIKRIQGRIDWNPTFLYLLEEE
                     FTVYEGTELVNFINPGRPIVSNNFLVKYGEYVEEVGLKRVPKKKPRKTYRLK"
     gene            24800..25446
                     /locus_tag="VYN12_001111"
                     /pseudo
     CDS             24800..25446
                     /locus_tag="VYN12_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730888.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25746..>26667
                     /gene="pspC"
                     /locus_tag="VYN12_001112"
     CDS             25746..>26667
                     /gene="pspC"
                     /locus_tag="VYN12_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HEV1415513.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDSERDKARKEVEEYVKKIVGESYAKSTKKRHTNTVALV
                     NELNNIKNEYLNKIVESTSESQLQILMMESRSKVDEAVSKFESKFEKDSSSSSSSDSS
                     TKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKIL
                     DDIQKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGL
                     TQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQ"
BASE COUNT         8406 a         4551 c         5965 g         7745 t
ORIGIN      
        1 cgagtcaata ctatttggag cccctttata acctcttgcg agagagacta ttgactcagc
       61 ccttacttca tgcggatgaa acttcttata gggtgctaga gagtgatagt cagctgactt
      121 actattggac ttttttgtct gggaaagctg agaaacaagg gattacgctt taccatcatg
      181 tcctaatcga cttgttcata tcttatttca atccattata aatagtgaga aatatctatc
      241 ctatcttcta gaatgtcttc caaacgtgga aactctcgta aacaaagagg ttttagaggc
      301 ctatttacca tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
      361 aactatccgt gagttctcta gtctggagat ttttcaatat acttcgttat tggacggtta
      421 caattcataa agtgctgtag agagataacg ttcaccgtta tctggtgcta gggcaaggac
      481 ttttttacct gtacctaatt ttttggcaac ctcgatggct ccgtagatag ctgcagctga
      541 ggaaatccct acaaggaagc cttcttttcc accaatttca cgtccgagtg caagagcgtc
      601 atctgatgtt acacgaacga taccatcata ggctttagta tcaagtgtat caggaataaa
      661 tccagctgag ataccttgaa ttttgtgagg accaggtttt tcaccagata gaatagcaga
      721 ttcatctgct tctactgcaa aaacttgaat gttagaattt tctgatttga gtgcatgaga
      781 aacaccagaa atcgttccac cggtacctac tccagcaaca aaggcatcta atccatcttt
      841 accgaaagca gctagtatct cagctcctgt tgttctttcg tgtacttctg gattagctgg
      901 attgtcaaat tgaagaggaa ggaaaccatc acgttcagca gcgatttctt gagccttagc
      961 aatagcacct ttcattccct cgctaccagg agttaggacg agttcagcac cataagcttg
     1021 gataatttta cgtcgttcta cactcatagt ttcaggcata acgatgacga ctttataccc
     1081 tttagcagca cctacccatg aaagtccaat accagtgttt ccacttgttg cttcaacaat
     1141 agtagaacca ggtttcagaa taccatcttg ttcagctttt tcaatcatgc taagggcaat
     1201 acggtctttt acagatgaac caggattaaa tgcttcaagc tttatataga cgtctgcagc
     1261 accttctggc acgatgttgt taagtttaac aatcggtgtt tgaccgatta attcagtaat
     1321 gttgttataa atagacatat gaatacctct ttgtataaga tatctttagt ataacgatat
     1381 ctataccatt tgtaaaatat agaaatccta tcaaagcgat aggatttttt tatatcatag
     1441 atcaaagtca ttaattttca agtgattgtg ttcagctaat tctagtaaat aggtgtgaag
     1501 gaaaacgata tcaggtttcg tttgaattgc ttcattttct agtatatttt ggtacgcatc
     1561 tttttatttt gctcgctaaa gtagttgtga gagtgtcaac gaaacgctgt attattcatt
     1621 gtttacacta agtttacagg aacttcaaca tctcgtaaac cttggtcagt taaagtgact
     1681 tttccattaa aaaactccac aagtgcagct ttaatagttt ctttttcttc tttatcaaca
     1741 taaatcatcg tatcgacttg atctgtaaag tttgtatcca gctccatgag atcatgttct
     1801 ttaaggaagt tactgtactc ttggtactga gcataagaca tttgaatagc aatgccagcc
     1861 tgttctttta tttcaataat accaatttct ttgacagcta aggcgacact gccggcgtaa
     1921 gcacgaatta gtcctccagc gcctagttta ataccaccaa agtagcgtgt cacgaccaca
     1981 cagacattgg tgagattgtg attttctagt accccaagca tgggaacacc agcagtacca
     2041 ctaggctcac catcatcact tgtacgttta atttcactac gttctccaat aataaaggca
     2101 gagcagttat gtgtcgcttt gtagtgttct tttttgatgg cagtaatgaa gtcacgagcc
     2161 tcttcttcgc tataaacacg cttggcatgg cagataaagc gagatttttt gatttcttct
     2221 tggacttgac cgtcctcttt aattgttcta aattccatga tttaattgta ctaaaaaatc
     2281 atctaaagtg ctagttttta cgaataaaga agtatgaaag taaatttaga ttatctcggt
     2341 cgtttattta ctgagaatga attaacagaa gaagaacgtc agttggcgga gaaacttcca
     2401 gcaatgagaa aggagaaggg gaaacttttc tgtcaacgct gtaatagtac tattctagaa
     2461 gaatggtatt tgcccatcgg tgcttactat tgtcgagagt gcttgctgat gaagcgagtc
     2521 agaagtgatc aaactttata ctattttccg caggaggatt ttccgaagca agatgttctc
     2581 aaatggcgcg gccaattaac tccttttcaa gagaaggtgt cagagggact gcttcaagca
     2641 gtagacaagc aaaagccaac cttagttcat gcggtaacag gagctggaaa gacagaaatg
     2701 atttatcaag tagtggctaa agtgatcaat gcgggtggtg cagtgtgttt ggctagtcct
     2761 cgcatagatg tttgtttgga gctgtacaag cgcctgcaac aggatttttc ttgcggtata
     2821 gctttgctac atggagaatc ggaaccttat tttcgaacac cactagttgt tgcaacaacc
     2881 catcagttat tgaagtttta tcaagctttt gatttgctga tagtggatga agtagatgct
     2941 tttccttatg ttgataatcc catgctttac cacgctgtca agaatagtgt aaaggagaat
     3001 ggattgagaa tctttttaac agcgacttcg accaatgagt tagataaaaa ggtccgttta
     3061 ggagaactaa aaagactgaa tttaccgaga cggtttcatg gaaatccgtt gattattcca
     3121 aaaccaattt ggttatcgga ttttaatcgc tacttagaca agaatcgttt gtcaccaaag
     3181 ttaaagtcct atattgagaa gcagagaaag acagcttatc cgttactcat ttttgcttca
     3241 gaaattaaga aaggggagca gttagcagaa atcttacagg agcaatttcc aaatgagaaa
     3301 attggctttg tatcttctgt aacagaggat cgattagagc aagtacaagc ttttcgagat
     3361 ggagaactga caatacttat cagtacgaca atcttggagc gtggagttac cttcccttgt
     3421 gtggatgttt tcgtagtaga ggccaatcat cgtttgttta ccaagtctag tttgattcag
     3481 attggtggac gagttggacg aagcatggat agaccgacag gagatttgct tttcttccat
     3541 gatgggttaa atgcttcaat caagaaggcg attaaggaaa ttcagatgat gaataaggag
     3601 gctggtctat gaagtgcttg ttatgtgggc agactatgaa gactgtttta acttttagta
     3661 gtctcttact tctgaggaat gatgactctt gtctttgttc agactgtgat tctacttttg
     3721 aaagaattgg ggaagagaac tgtccaaatt gtatgaaaac agagttgtca acaaagtgtc
     3781 aagattgtca actttggtgt aaagagggag ttgaagtcag tcatagagcg atttttactt
     3841 acaatcaagc tatgaaggat tttttcagtc ggtataagtt tgatggagac ttcctgttaa
     3901 gaaaagtttt cgcttcattt ttaagtgagg agttgaaaaa gtacaaagag tatcaatttg
     3961 ttgtaattcc cctaagtcct gatagatatg ctaatagagg atttaatcag gttgagggct
     4021 tggtagaggc agcaggcttt gagtatctgg atttattaga gaaaagagaa gagagagcca
     4081 gttcttctaa aaatcgttca gagcgcttgg ggacagaact tcctttcttt attaaaagtg
     4141 gagtcactat tcctaaaaaa atcctactta tagatgatat ctatactaca ggagcaacta
     4201 taaatcgtgt taagaaactg ttggaagaag ctggtgctaa ggatgtaaaa acattttccc
     4261 ttgtaagatg aggaaaaaat ttgcaaaaat agaatgaaag cgttataata aaatcataaa
     4321 aacaaaaatg tttagaaaga aggtactcat atgattaaat atagtatccg tggtgaaaac
     4381 ctagaagtaa cagaagcaat tcgtgattat gtagtttcta aactcgaaaa gatcgaaaag
     4441 tacttccaac cagaacaaga gttggatgcc cgaattaact taaaagttta tcgtgaaaaa
     4501 acggctaaag tggaagtaac gattccgctt ggatctatta ctctccgcgc agaagatgta
     4561 tctcaagata tgtatggttc aattgacctt gtaactgata aaattgaacg tcagattcgt
     4621 aaaaataaaa caaaaatcga gcgtaaaaat aaaaataagg tagcaactgg tcaattattt
     4681 acagatgctt tggtggaaga ttcaaatgtt gtccagtcta aagttgttcg ttcaaaacaa
     4741 attgatttaa aaccaatgga tttggaagaa gcaattctac aaatggattt attggggcat
     4801 gatttcttta tctatgtgga tgttgaagat cagacaacca atgtgattta tcgtcgtgag
     4861 gatggcgaaa ttggtttgtt agaggttaaa gaatcttaat ttcaatatgt gtaaaggtag
     4921 gtttactgaa ttgtaaacta cctttttctt ataattgata gaattactga ttacactttt
     4981 aaaaagtcgc tttttgaggg gtattatggt ataatgggtg ccaagaggtt ttgaatgaaa
     5041 aaattttatg taagtccaat ttttcctatt ctagtaggat tgattgcgtt tggagtctta
     5101 tccactttca ttatttttgt taataataat ctgttgacgg ttttaatttt gtttcttttt
     5161 gtaggaggct atgttttttt atttaagaaa ctgagagtgc attatacaag gagtgatgta
     5221 gaacagatac agtatgtaaa ccaccaagcg gaagaaagtt tgacatctct attggaacaa
     5281 atgcctgtag gtgttatgaa attgaattta tcttctggag aggttgagtg gtttaatccc
     5341 tatgctgaat tgattttgac caaggaagat ggtgattttg atttagaagc tgttcaaacg
     5401 attatcaagg cttcagtagg aaatccgtct acttatgcca agcttggtga gaagcgttat
     5461 gctgttcata tggatgcttc ttccggtgtt ttgtattttg tagatgtatc cagggaacaa
     5521 gccataacag atgaattggt aacaagtcga ccagtgattg ggattgtctc tgtggataat
     5581 tatgatgatt tggaggatgc aacttctgag tcagatatta gtcaaatcaa tagttttgta
     5641 gctaatttta tatcagagtt ttcagaaaaa tacatgatgt tttctcgtcg ggtaagtatg
     5701 gatcgatttt atctatttac tgactacacg gtgcttgagg gcttgatgaa tgataaattt
     5761 tctgttattg atgctttcag agaagagtcg aaacagagac agttgccctt gaccttaagt
     5821 atgggatttt cttatggcga tggaaatcat gatgagatag ggaaagttgc tttgctcaat
     5881 ttgaacttgg ctgaagtacg tggtggcgac caggtggttg ttaaggaaaa cgacgaaacg
     5941 aaaaatccag tttattttgg tggtgggtct gctgcttcaa tcaagcgtac acggactcgt
     6001 acgcgcgcta tgatgacagc tatttcagat aagattcgga gtgtagatca tgtttttgta
     6061 gtcggtcaca aaaatttaga catggatgct ttgggctctg ctgtaggtat gcagttgttc
     6121 gccagcaatg tgattgaaaa tagctatgct ctttatgatg aagaacaaat gtctccagat
     6181 attgaacgag ctgtttcatt catagaaaaa gaaggagtta cgaagttgtt gtctgttaag
     6241 gatgcaatgg ggatggtgac caatcgttct ttgttgattc ttgtagacca ttcaaagaca
     6301 gccttaacat tatcaaaaga attttatgat ttatttaccc aaaccattgt tattgaccac
     6361 catagaaggg atcaggattt tccagataat gcggttatta cttatatcga aagtggtgca
     6421 agtagtgcca gtgagttggt aacggaattg attcagttcc agaattctaa gaaaaatcgt
     6481 ttgagtcgta tgcaagcaag tgtcttgatg gctggtatga tgttggatac taaaaatttc
     6541 acctcgcgag taactagtcg gacatttgat gttgctagct atctcagaac gcgcggaagt
     6601 gatagtattg ctatccagga aatcgctgcg acagattttg aagaatatcg tgaggtcaat
     6661 gaacttattt tacaggggcg taaattaggt tcagatgtac taatagcaga ggctaaggac
     6721 acgaaatgct atgatacagt tgttattagt aaggcagcag atgccatgtt agccatgtca
     6781 ggtattgaag cgagttttgt tcttgcgaag aatacacaag gatttatctc tatctcagct
     6841 cgaagtcgta gtaaactgaa tgtacaacgg attatggaag agttaggcgg tggaggccac
     6901 tttaatttgg cagcagctca aattaaagat gtaaccttgt cagaagcagg tgaaaaactg
     6961 acagaaattg tattaaatga aataaaggaa aaggagaaag aagaatgaaa gtaatctttt
     7021 tagcagatgt taaaggaaaa ggtaaaaaag gcgaaattaa ggaagtacca acagggtatg
     7081 cgcaaaactt tcttatcaaa aagaatctag ccaaagaagc gactgctcaa gctgtaggtg
     7141 aacttcgtgg taaacaaaaa tcggaagaaa aagctcacgc tgagatgatt gcagaaggga
     7201 aagcaattaa agcacaactt gaagcagaag aaactgttgt agaatttgtt gaaaaagttg
     7261 gtccagatgg tcgtaccttt ggttctatta ccaataagaa gattgcagaa gaattacaaa
     7321 agcaatttgg aattaagatt gataaacgtc atattcaagt acaagctccg attcgagcgg
     7381 ttggtttgat tgatgtgcca gtgaaaatct atcaagatat cacaagtgta atcaatcttc
     7441 gtgtgaaaga aggataagtt tacaccttct tgacaagatt gtaaaaggaa gggaagtctg
     7501 atggcagaag tagaagagtt acgagtacaa cctcaagata tcttagctga gcaatccgtt
     7561 ttaggggcta tctttattga tgagagtaaa cttgtttttg tgcgagaata cattgagtct
     7621 cgggactttt ttaagtatgc ccatcgtttg attttccaag ccatggtcga tttatccgat
     7681 cgtggtgatg ccatagatgc aacaacggtt cgtactatcc ttgataatca aggtgattta
     7741 cagaatattg gtggcttgtc ttacttggtt gagattgtca attctgtgcc aacttctgct
     7801 aatgcggagt attatgctaa gattgttgca gaaaaagcaa tgctacgtcg tttaattgcc
     7861 aagttgacag agtctgtcaa ccaagcttac gaagcgtcac aaccagctga tgaaattatt
     7921 gctcaggcag aaaaagggct gattgatgtc agtgaaaatg caaatcgaag cgggtttaag
     7981 aacattcgag atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc gcaacaaacg
     8041 accgatatta caggtattgc gacaggttat cgtgatttgg atcatatgac aacaggactt
     8101 catgaggagg agttgattat cttagcagct cgtccagcag ttggtaagac agcatttgcc
     8161 ttgaatatcg ctcagaatat tgggactaag ttggacaaaa cggttgctat tttttcactc
     8221 gaaatgggtg cggaaagctt ggtagaccgt atgttagctg cagaaggctt ggtggagtca
     8281 cattctatcc gtacagggca attgacagat gaggagtggc aaaaatatac tattgctcag
     8341 ggtaatctag ctaacgccag tatctatatc gatgatacgc caggtattcg gattacagag
     8401 attcgttctc gttctcgtaa attggctcaa gaaactggaa atcttggttt gattttgata
     8461 gactatttgc aacttatcac gggaactggt cgagaaaatc gtcaacaaga agtttctgaa
     8521 atttctcgtc agttgaaaat actagccaag gaattgaagg ttccagtaat cgctctgagt
     8581 cagctttctc gtggtgtaga acaacgtcag gacaagagac cggtcttgtc tgatattcgt
     8641 gaatctgggt ctattgagca ggacgctgat atcgtagctt ttctctatcg cgatgactac
     8701 tatgaacgtg gtggtgaaga agaggagggt atcccaaata ataaggtgga agttattatc
     8761 gagaaaaacc gtagtggagc tcgtggaaca gtggaattga ttttccaaaa agaatacaat
     8821 aaattttcaa gtatctcaaa gagggaggca taagatgtca gatgcattta cagatgtagc
     8881 caagatgaaa aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg tagaaatgac
     8941 tttggagaat ggtcgtaagc gccaaaaaaa tagattaggt aagctaattg aagtttatcc
     9001 atccctattt attgtggagt ttggggatgt ggaaggagat aaacaagtta atgtttacgt
     9061 tgaatccttt acttactcag atattcttac agaaaagaat ttgattcatt atcttgacta
     9121 aagtgagaaa ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat
     9181 cgctttatat tatttttcaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa
     9241 caagttatta cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga
     9301 tgctagcagc tggtgatagt gtctatgcct attccagagg aaatggatcg attgcgcgtg
     9361 gggatgatta tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt
     9421 attctcgtca gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa
     9481 ttccggcagc ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc
     9541 gtgtagataa tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc
     9601 atgtagcctg ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg
     9661 gttatacaga atcctataat aaacgagtta taaaagcaaa cacgatgaca ggatttattc
     9721 attttaaaga tttggatggt ggcagtgttg ggaatagtca atcctcagct tcaacaggcg
     9781 gaactcatta ttttaagacc aagtctgcta ttaaaactga acccctagtt agtgcaactg
     9841 tgattgatta ctattatcct ggggagaagg ttcattatga tcagatactt gaaaaagacg
     9901 gctataagtg gttgagttat actgcctata atggaagtta tcgttatgtt caattggagg
     9961 ctgtgaataa aaatcctcta ggtaattctg ttctttcttc aacaggtgga actcattatt
    10021 ttaagaccaa gtctgctatc aaaactgaac ccctagttag cggaactgtg attgattact
    10081 attatcctgg ggagaaggtt cattatgatc agatacttga aaaagacggc tacaagtggt
    10141 tgagttatac tgcctataat ggaagtcgtc gctatataca gctagaggga gtgacttctt
    10201 cacaaaatta tcagaatcaa tcaggaaata tctctagcta tggatccaat aatagttcaa
    10261 ctgtcggttg gaagaaaata aatggtagtt ggtatcattt caaatcaaat ggttctaaat
    10321 caacaggatg gctgaaagac ggttctagct ggtattattt gaaattatct ggtgaaatgc
    10381 agacaggatg gttaaaggag aatggctcgt ggtattatct gggtagttca ggggcaatga
    10441 aaacaggctg gtaccaggtc tctggtaagt ggtattattc ttactcttca ggcgccttag
    10501 ctgttaatac gacggtggat ggctacagag taaacagtga tggagaacga gtatagaaaa
    10561 ttggagtagg agaaatttcc tgctcttttc tgtaagcagt ttccttgaca tttttcttat
    10621 tttgcgctat catatataca tataatatat gggagtctgt gtacagtctg agaggaagtg
    10681 ttaaacttcg accgcacctg atctgggtaa tgccagcgga gggaacgata cttagtctaa
    10741 ttttgcacct tttccatgta tggtaaaggt ttttcttttt tttaaaagga aaacgagaag
    10801 aggaggttct tatgaaagca agcattgcct tgcaagtttt acccctagca caggggattg
    10861 atcggatagc tgttattgat caggtcattg cttatctgca aactcaagaa gtgacgatgg
    10921 tagtgacacc atttgaaacg gtcttggaag gggagtttga tgagcttatg cgcattctaa
    10981 aagaagcgct ggaagtggca gggcaggagg cagacaatgt ctttgccaat gtcaaaataa
    11041 atgtaggaga gattttaagt attgatgaga aacttgagaa gtatactgag acgacacatt
    11101 agtctattgg gctttctcgg agtattgtca atctggcagt tagcaggttt tcttaaactt
    11161 ctccccaagt ttatcctgcc gacacctctt gaaattctcc agccctttgt tcgtgacaga
    11221 gaatttctct ggcaccatag ctgggcgacc ttgagagtgg ctttactggg gctgattttg
    11281 ggagttttga ttgcctgtct tatggctgtg ctcatggata gtttgacttg gctcaatgac
    11341 ctgatttacc ctatgatggt ggtcattcag accattccga ccattgccat agctcctatc
    11401 ctggtcttgt ggctgggtta tgggattttg cccaagattg tcttgattat cttaacaaca
    11461 acctttccca tcatcgttag tattttggac ggttttaggc attgtgacaa ggatatgctg
    11521 actttgttta gtctgatgcg agcaaaccct tggcaaatcc tgtggcattt taaaatcccg
    11581 gttagcctgc cttactttta tgcaggtctg agggtcagtg tctcctacgc ctttatcaca
    11641 actgtggtat ctgagtggtt gggaggtttt gaaggtcttg gtgtttatat gattcagtct
    11701 aaaaaactgt ttcagtatga taccatgttt gccattatta ttctggtgtc gattatcagt
    11761 cttttgggta tgaagctggt cgatatcagt gaaaaatatg tgattaaatg gaaacgtact
    11821 taaaatagag cgtttttgaa aaagaaaaga ggaaatcaaa atgaagaaaa catggaaagt
    11881 gtttttaacg cttgtaacag ctcttgtagc tgttgtgctt gtggcctgtg gtcaaggaac
    11941 tgcttctaaa gacaacaaag aggcagaact taagaaggtt gactttatcc tagactggac
    12001 accaaatacc aaccacacag ggctttatgt tgccaaggaa aaaggttatt tcaaagaagc
    12061 tggagtggat gttgatttga aattgccacc agaagaaagt tcttctgact tggttatcaa
    12121 cggaaaggca ccatttgcag tgtatttcca agactacatg gctaagaaat tggaaaaagg
    12181 agcaggaatc actgccgttg cagctattgt tgaacacaat acatcaggaa tcatctctcg
    12241 taaatctgat aatgtaagca gtccaaaaga cttggttggt aagaaatatg ggacatggaa
    12301 tgacccaact gaacttgcta tgttgaaaac cttggtagaa tctcaaggtg gagactttga
    12361 gaaggttgaa aaagtaccaa ataacgactc aaactcaatc acaccgattg ccaatggcgt
    12421 ctttgatact gcttggattt actacggttg ggatggtatc cttgctaaat ctcaaggtgt
    12481 agatgctaac ttcatgtact tgaaagacta tgtcaaggag tttgactact attcaccagt
    12541 tatcatcgca aacaacgact atctgaaaga taacaaagaa gaagctcgca aagtcatcca
    12601 agccatcaaa aaaggctacc aatatgccat ggaacatcca gaagaagctg cagatattct
    12661 catcaagaat gcacctgaac tcaaggaaaa acgtgacttt gtcatcgaat ctcaaaaata
    12721 cttgtcaaaa gaatacgcaa gcgacaagga aaaatggggt caatttgacg cagctcgctg
    12781 gaatgctttc tacaaatggg ataaagaaaa tggtatcctt aaagaagact tgacagacaa
    12841 aggcttcacc aacgaatttg tgaaataatg acagaaatta gactagagca cgtcagttat
    12901 gcctatggtc aggagaggat tttagaggat atcaacctac aggtgacttc aggcgaagtg
    12961 gtttccatcc taggcccaag tggtgttgga aagaccaccc tctttaatct aatcgctggg
    13021 attttagaag ttcagtcagg gagaattgtc cttgatggtg aagaaaatcc caaggggcgc
    13081 gtgagttata tgttgcaaaa ggatctgctc ttggagcaca agacggtgct tggaaatatc
    13141 attctgcccc tcttgattca aaaggtggat aaggcagaag ctatttcccg agcggataaa
    13201 attcttgcga ccttccagct gacagctgta agagacaagt atcctcatga acttagcggt
    13261 gggatgcgcc agcgtgtagc cttactccgg acctaccttt ttgggcacaa gctctttctc
    13321 ttagatgagg cctttagcgc cttggatgag atgacaaaga tggaactcca cgcttggtat
    13381 cttgagattc acaagcagtt gcagctaaca accctgatca tcacgcatag tattgaggag
    13441 gccctcaatc tcagcgaccg catctatatc ttgaaaaatc gccctgggca gattgttgca
    13501 gaaattaaac tagattggtc tgaagatgag gacaaggaag tccaaaagat tgcctacaaa
    13561 cgtcaaatct tggcagaatt aggcttagat aagtagaaaa atagggagtt ggtgaagatt
    13621 atcctttacc agcgcccttt ttcttttaaa aatgagaaaa tttcggtata atagtcaaac
    13681 aaggtcaagg tttaaagaga gaggtgggtt tgttatgaga tttaaaaata catcggatca
    13741 tattgaggcc tacatcaagg cgattttaga tcaatctggt atcgtggagt tgcaacggag
    13801 tcagttggca gatacctttc aggttgttcc tagtcagatt aactacgtga tcaagacacg
    13861 ctttacggaa agtagaggct acttggttga aagtaagcgt ggtggcggag gctacattcg
    13921 tataggacgg attgagtttt ctagtcatca tgaaatgctc cgggagctgc tttactcgat
    13981 tggtgagcga gtcagtcaag aaatttatga ggatattctc cagcttttgg ttgagcagga
    14041 attgatgacc aagcaggaga tgaatttgct agaatcagta gctttggatc gcgttttagg
    14101 agaagaagct ccagttgttc gagcaaacat gctacgtcag atcatacaag aggtagatag
    14161 aaaagggaag taagatgaac tattcaaaag cattgaatga atgtatcgaa agtgcctaca
    14221 tggttgctgg acattttgga gctcgttatc tagagtcttg gcacttgttg attgccatgt
    14281 ctaatcacag ttatagtgta gcaggggcaa ctttaaatga ttatccgtat gagatggacc
    14341 gtttagaaga ggtggctttg gaactgactg aaacggacta tagccaggat gaaaccttta
    14401 cggaattgcc gttctcccgt cgtttgcagg ttctttttga cgaagcagag tatgtagcgt
    14461 cagtggttca tgctaaggtg ctagggacag agcacgtctt ctatgcgatt ttgcatgatg
    14521 gcaatgcctt ggcaactcgt atcttggaga gggctggttt ttcttatgaa gacaagaaag
    14581 atcaggtcaa gattgctgct cttcgtcgaa atttagaaga acgggcaggc tggactcgtg
    14641 aagacctcaa ggctttacgc caacgccatc gtacagtagc tgacaagcaa aattctatgg
    14701 ccaatatgat gggcatgccg cagactccta gtggtggtct cgaggactat acgcatgatt
    14761 tgacagagca agcgcgttct ggcaagttag aaccagtcat cggtcgggac aaggaaatct
    14821 cacgtatgat tcaaatcttg agccggaaga ctaagaacaa ccctgtcttg gttggggatg
    14881 ctggtgtcgg gaaaacagct ctggcgcttg gtcttgccca gcgtattgct agtggtgacg
    14941 tgcctgcgga aatgtctaag atgcgcgtgt tagaacttga tttgatgaat gtcgttgcag
    15001 ggacacgctt ccgtggtgac tttgaagaac gcatgaataa tatcatcaag gatattgaag
    15061 aagatggcca agtcatcctc tttatcgatg aactccacac catcatgggt tctggtagcg
    15121 ggattgattc gactctggat gcggccaata tcttgaaacc agccttggcg cgtggaactt
    15181 tgagaacggt tggtgccacc actcaggaag aatatcaaaa acatatcgaa aaagatgcgg
    15241 ctctttctcg tcgtttcgct aaagtgacga ttgaagaacc aagtgtggca gatagtatga
    15301 ctattttaca aggtttgaag gcgacttatg agaaacatca ccgtgtacaa atcacagatg
    15361 aagcggttga aacagcggtt aagatggctc atcgttattt aaccagtcgt cacttgccag
    15421 actctgctat cgacctcttg gacgaagcag cagcaacagt gcaaaataag gcaaagcatg
    15481 taaaagcaga cgattcagat ttgagtccag ctgacaaggc cctgatggat ggcaagtgga
    15541 aacaggcagc ccagctaatc gcaaaagaag aggaagtgcc tgtctacaaa gacttggtga
    15601 cagagtctga tattttgacc accttgagtc gcttgtcagg aatcccagtt caaaaactga
    15661 ctcaaacgga tgctaagaag tatttaaatc ttgaagcaga actccataaa cgggttatcg
    15721 gtcaagatca agctgtttca agcattagtc gtgcgattcg ccgtaatcag tcaggaattc
    15781 gcagtcacaa gcgtccgatc ggttccttta tgttcctagg acccacaggt gtcggtaaga
    15841 ccgagttggc caaggctttg gcagaagttc tctttgatga cgaatcagcc cttatccgct
    15901 ttgatatgag tgagtatatg gagaaattcg cagccagccg tctaaatgga gctcctccag
    15961 gctatgtggg ttacgaagaa ggtggggagt taacagagaa ggttcgcaat aaaccctatt
    16021 ccgttctcct ctttgatgag gtagagaagg ctcacccaga tatctttaat gttctcttgc
    16081 aggttctgga tgacggtgtc ttgacagata gcaagggacg caaggtcgat ttttcaaata
    16141 ccattatcat tatgacatcg aatctaggtg cgactgccct tcgtgatgat aagactgttg
    16201 gttttggggc taaggatatt cgttttgacc aggaaaatat ggaaaaacgc atgtttgaag
    16261 aactgaaaaa agcttataga ccggaattca tcaaccgtat tgatgagaag gtggtcttcc
    16321 atagcctatc tagtgaccat atgcaggaag tggtgaagat tatggtcaag cctttagtgg
    16381 caagtttggc tgaaaaaggc attgacttga aattacaagc ttcagctctg aaattgttag
    16441 caaatcaagg atatgaccca gagatgggag ctcgcccact tcgcagaacc ctgcaaacag
    16501 aagtggagga caagttggca gaacttcttc ttaagggaga tttagtggca ggcagcacac
    16561 ttaagattgg tgtcaaagca ggccagttaa aatttgatat tgcataaaag aataaaagta
    16621 tcagcatctg accataagtc acagtggagt gaaactcaat gaaaatcaaa gagcaaacta
    16681 ggcagctagc cgcaggttgc ttaaaacact gttttgaggt tgcagataga gctgacgtgg
    16741 tttgaagaga ttttcgaaga gtatgaaact aaaacctata gcttctaaac gattcgtggt
    16801 tttcaccatt caacacaaaa ttcatatgtt tattaccctc cgtcgtattt gtcttagagc
    16861 gtgtgtagta gaaaaagagc agtcttatct gaaattttta ttctttcaaa agagacctgt
    16921 ttcttttttg catgtcaaat ccgttctaac tggtatttga aaaatcaaac taatactcaa
    16981 tgaaaatcaa agaacaaact aggcagctag ccgcaggttg ctcaaaacac tgttttgagg
    17041 ttgtagatag agctgacgtg gtttggagag attttcgaag agtataagct gcaagatgaa
    17101 tgattttctt gtattgacgt tgttgttgac aaaaagtagc ggataaatga aatccattct
    17161 attatcatag atgataggct ggtaggaaat tttcaaatag catacaggaa atagatgtat
    17221 ggagttctgg tagtagaaag ggagagagat gaacatttta gttgcagatg acgaggaaat
    17281 gattagagaa ggaattgcag catttctgac agaagagggt tatcatgtca ttatggctaa
    17341 ggatggacaa gaggtcttgg aaaaatttca agatctccct atccatctca tggtactgga
    17401 tttaatgatg cctaggaaga gtggttttga agtgttaaaa gaaatcaatc aaaagcacga
    17461 tattcctgtc atcgtcttga gtgctctggg agatgaaact actcagtcac aggtatttga
    17521 tctctatgct gatgatcatg tgacaaaacc tttttctttg gtactgcttg tcaagcgtat
    17581 taaggcgctt atcagacgtt actacgtcat agaggatatt tggcgatatc aggatgtaac
    17641 agtggatttt acctcttaca aagcacatta taaaaatgaa gaaattgatc tcaaaccaaa
    17701 ggaattactg gtactaaagt gtttgattca gcataaaaat caagttttaa gtagagagca
    17761 gatattggaa gaaatttcaa aagatgtagc tgatttacct tgtgataggg tcgttgatgt
    17821 ctatattcgt actcttcgca aaaaattagc tttagattgt atcgtgactg tgaaaaatgt
    17881 tgggtataag attagcttat gataaaaaat cctaaattat taaccaagtc ttttttaaga
    17941 agttttgcaa ttctaggtgg tgttggtcta gtcattcata tagctattta tttgaccttt
    18001 cctttttatt atattcaact ggagggggaa aagtttaatg agagcgcaag agtgtttacg
    18061 gagtatttaa agactaagac atctgatgaa attccaagct tactccagtc ttattcaaag
    18121 tccttgacca tatctgctca ccttaaaaga gatattgtag ataagcgcct ccctcttgtg
    18181 catgacttgg atattaaaga tggaaagcta tcaaattata tcgtgatgtt agatatgtct
    18241 gttagtacag cagatggtaa acaggtaacc gtgcaatttg ttcacggggt agatgtctac
    18301 aaagaagcaa agaatatttt gcttttgtat ctcccatata catttttggt tacaattgct
    18361 ttttcctttg ttttttctta tttttatact aaacgcttgc tcaatcctct tttttacatt
    18421 tcagaagtga ctagtaaaat gcaagatttg gatgacaata ttcgttttga tgaaagtagg
    18481 aaagatgaag ttggtgaagt tggaaaacag attaatggta tgtatgagca cttgttgaag
    18541 gttattcatg agttggaaag tcgtaatgag caaattgtaa aattgcaaaa tcaaaaggtt
    18601 tcctttgtcc gcggagcatc acatgagttg aaaacacctt tagccagtct tagaattatc
    18661 ctagagaata tgcagcataa tattggagat tacaaagatc atccaaaata tattgcaaag
    18721 agtataaata agattgacca gatgagccac ttattggaag aagtactgga gtcttctaaa
    18781 ttccaagagt ggacagagtg tcgtgagacc ttgactgtta agccagtttt agtagatatt
    18841 ttatcacgtt atcaagaatt agctcattca ataggtgtta caattgaaaa tcaattgaca
    18901 gatgctacca gggtcgtcat gagtcttagg gcattggata aggttttgac aaacctgatt
    18961 agtaatgcaa ttaaatattc agataaaaat gggcgcgtaa tcatatccga gcaagatggc
    19021 tatctctcta tcaaaaatac atgtgcgcct ctaagtgacc aagaactaga acatttattt
    19081 gatatattct atcattctca aatcgtgaca gataaggatg aaagttccgg tttgggtctt
    19141 tacattgtga ataatatttt agaaagctat caaatggatt atagttttct cccttatgaa
    19201 cacggtatgg aatttaagat tagcttgtag acagattagt tttttattaa agttcatata
    19261 gggttaacat aagtgtgtta ttctttgtgt agataaaaga aaggatacta atatggtatt
    19321 agcgattatt ttagtaacat tccttattcg attgattttt ttaaagcgtt cgatagagaa
    19381 tgagaaacga atccttagca atggcgggaa agaatttgga gttgagaata caaaacgatt
    19441 aactatggct catattgttt tttatctctc ttgcttggtt gaggcaatgg tgcacaagac
    19501 aatttttgat ggcatgggca tggttggttt agtcttgctt attttttcta tgctgatgtt
    19561 gatgttggtg attcacttgt tgggagatat ttggacagtg aagcttatgc ttgtcaataa
    19621 tcacaaatat gtagatcata ttttgtttag gacagtaaaa catcctaatt actttttaaa
    19681 tattcttcct gagttgattg gcttgacctt gttgagtcat gcttatgtga cttttgtttt
    19741 agtttttcca gtttatgcag ttattttgta tcgacgaata gctgaagagg aaaagctatt
    19801 acatgaagtt ataatcccaa atggaagcat aaagagataa atacaaaatt cgatttatat
    19861 acagttcata ttgaagtgat atagtaaggt taaagaaaaa atataggaga taattatgtt
    19921 tgcatcaaaa aacgaaagaa aagtacatta ttcaattcgt aaatttagta ttggagtagc
    19981 tagtgtagct gttgctagct tgttcttagg aggagtagcc catgcagaag gggttagaat
    20041 tgggaataac tccacggtta catctagtgg ggatgaagtc gagtcgcatc tacaaagtat
    20101 attgaaggat gtcaataaaa atttgaaaaa agttcaacat acccaaaatg tcggcttact
    20161 cacaaagttg agcgaaatta aacggaagta tttgtatgaa ttaaaagtta atggtttaga
    20221 agagaagtcg aaagctgagt tgacgtcaaa aacaaaaaaa gagttaaccg cagcttttga
    20281 gcagtttaaa aaagatacat tatcaacaga actagaaaaa aaggtagcag aagctcagaa
    20341 gaaggttgaa gaagctgaga aaaaagccaa ggatcaaaaa gaagaagatc gccgtaacta
    20401 cccaaccaat acttacaaaa cgcttgaact tgaaattgct gagtccgatg tgaaagttaa
    20461 agaagcggag cttgaactag taaaagagga agttaacgaa cctcgaaacg aggaaaaagt
    20521 taagcaagca aaagcggaag ttgagagtaa aaaagctgag gctacaaggt tagaaaaaat
    20581 caagacagat cgtaaaaaag cagaagaagc taaacgaaaa gcagcagaag aagataaagt
    20641 taaagaaaaa ccagctccag caccacaacc agcgccggct cctcaaccag aaaaaccagc
    20701 tgaagaaact ccagctccag ctccaaaacc agagaagcca actgaacaac caaaagcaga
    20761 aaaaccagat gatcaacaag cagaagaaga ctatgctcgt agatcagaag aagaatataa
    20821 tcgcttgact caacagcaac cgccaaaacc agagcaacca gctcctgcac caaaaatagg
    20881 ctggaaacaa gaaaacggta tgtggtactt ctacaatact gatggttcaa tggcgacagg
    20941 atggctccaa aacaacggtt catggtacta tctaaacgct aatggtgcta tggcgacagg
    21001 atggctccaa aacaatggtt catggtatta cctcaacgct aatggttcaa tggcgacagg
    21061 atggctccaa tacaatggtt catggtacta cctaaacagc aatggcgcta tggcgacagg
    21121 atggctccaa aacaatggtt catggtacta cctcaacgct aatggttcaa tggcgacagg
    21181 atggctccaa tacaatggtt catggtacta cctcaacagc aatggtgcta tggtaacagg
    21241 atggctccaa aacaatggct catggtacta cctcaacgct aacggttcaa tggcaacaga
    21301 ttgggtgaaa gatggagata cctggtacta tcttgaagca tcaggggcta tgaaagcaag
    21361 ccaatggttc aaagtatcag ataaatggta ctatgtcaat ggctcaggtg cccttgcagt
    21421 caacacaact gtagatagct atagagtcaa cgccaatggt gaatgggtaa actaaaccta
    21481 atataactag ttaatactga cttcctgtaa gaactcttta aagtattccc tacaaatacc
    21541 atatcctttc agtagataat atacccttgt aggaagttta gattaaaaaa taactctgta
    21601 atctctagcc ggatttatag cgctagagac tacggagttt ttttggctct ttgtcaactg
    21661 tagtgggttg aagaaaagtg gctaagctcg agaaaggaca aatttcgtcc tttctttttt
    21721 gatgttcaaa gcgataaaaa tccgtttttt gaagttttca aagttccgaa aaccaaaggt
    21781 attgcgtttg atgagtttaa tgagattatt ggtcgcttcc agtttggcgt tagaatagtg
    21841 tagttgaagg gcgttgataa tcttttcttt atctttgagg aaggttttaa agacagtctg
    21901 aaaaatagga tgaacctgct taagattgtc ctcaatgagt ccgaaaaatt tctctggttc
    21961 cttattctgg aagtgaaaaa gcaagagttg atagagatca tagtggtgtt tcaagtcttc
    22021 cgaatagctc aaaagcttgt ttaaaatctc tttattggtt aagtgcatac gaaaagtagg
    22081 acgataaaat cgcttatcac tcagtttacg gctatcctgt tgaatgagtt tccagtagcg
    22141 cttgatagcc ttgtattcat gggattttcg ctcaaactga ttcatgattt ggacacgcac
    22201 acgactcata gcacggctta gatgttgtac aatgtgaaag cgttcaaaaa cgatttcgct
    22261 atattcgaga ggcttttcgt gatgacgaat tgacctctgt ctgcaagtta gatgaaatca
    22321 atcttccccg ttaccctatg ggctggcagg agtggttaga ccagatgtta gcggaaattt
    22381 cctatgatga aaaccagcaa gagctgatct tctttgtagg agaagcagac tatcagcaag
    22441 aactatctaa acgtggattt ggcactgtct tgccagaaag aaagtttggt atctcggtga
    22501 ctatgattcg agaaaatcca agcaaatatt ggaaatacat cgctcaaccc ttccgtcgtc
    22561 agtttaccaa gaaagtattg atcatgggaa gtgccagcaa tgggaagacc actctagcca
    22621 aggatttggc taggtattac gatgcgcctg tcagtctgga atacgcacgt gagtatcaga
    22681 ttaaaaataa cgtccgcgac gatgaattga ctccaaagga ttactactat ctcctgttgg
    22741 gacagtatga ccagacctca aagttaatcg atagcaatgc caatcgaggt ttggtaatag
    22801 ccgataccaa ctccttggta accaagggct actatgatta ttacatggag acagagaacc
    22861 aagtggactt atcaggagaa acctttgaca atctctttgt ttcaatcttg gccaaggaaa
    22921 aatgggactt gattctcttt gtgcaacctg ttggctccta tgtcaatgac ggatttagag
    22981 atatgaccat ggcagaagag cacattcgct acagtttttc tcagcatttg gaccagatga
    23041 gggagagata cttaacgact attcctttag tttatctagc ggaggattat ctaggtaatt
    23101 atgaagcagc aaaagtgact attgatgcca tttaccaagc agattaggag aaaattatga
    23161 aaaagctaac tgaaaaaatc acacaattta tcgaaaactt taaaaatgtc catgccaaag
    23221 cccgaaagat tggttttgca gggttcatgc gcctgctctg gaaagatctc tttgttggtc
    23281 gtagcctttt ccagtggttg tatctcatcg ccttgtcaag tgttcccttg atcttaaagt
    23341 tcacgcaaaa tacaaaaagt catgactggc tgagcttgtt tgcatcctgg actgggattg
    23401 tctgtgtcat cttggtagca gaaggacgtg caagcaatta tctctttggg gctattaatt
    23461 cggctatcta tttgattttg gccatgaatg cgacttttta tggtgaagtt ttgacgacag
    23521 tttacttctt tgtcatgcag ccgattggtc tctgtgcttg gttgtccaat cgtatcaatg
    23581 accaaggtaa accagaagaa tcccactttg aagctaagaa attatctgtt cttgactggc
    23641 tcaagtactt aaccttgact gccatcatct ggattggtat gggcttggct taccaaagta
    23701 tcaatagcgc tcgtcctttc cgtgatagtg ttacctgttg gtcagctctt gatgacacgt
    23761 ctcaaccgtg agcaatggat tttctggatt gcaaccaatc tctttagtat ctatctctgg
    23821 tggggcgaaa atattcacat ccaagggatg tactgggttt acacattcaa tagtctagtg
    23881 tgacggtgga tatggtggcc tactgctttg tcgaaggaaa aatcaaactc ttgctgattc
    23941 gtcgcaaggc tcacccttat caaaactatt tagccttagt tggaggcttt atggacaagg
    24001 gagaagatgc tgcacatgcc tatcagcgcg aagtgaaaga agaagtcaat ctcgatcttc
    24061 ctttggaaaa aatcgagcag ttaatgaccg tatcgacccc tggtcgtgat ccacgggggt
    24121 ggacagtgac cattgcctat ttagtgtacc tacctagtcg tgcattagaa ctggttcagg
    24181 caagtgacga tgctaaggat gttgtttttg tagatgttga ctttcagacg gggaaatgct
    24241 accttgaggg agtggagctg gacgagcaag ccttagcctt tgaccattat gccattatcc
    24301 aaaaatccat caaacgaatc caaggccgta tcgactggaa cccgaccttc ctttatctgt
    24361 tggaagaaga gtttactgtc tatgaaggaa ccgaactggt caatttcatc aaccccggtc
    24421 gcccaatcgt cagcaataac tttctcgtaa aatacggcga atatgtagaa gaagtcggac
    24481 tcaaacgagt acctaaaaag aaaccaagaa aaacctatcg attgaaataa agaggtcgag
    24541 acaaagttcc cgacttcttt atttatcatc attttttatg aatggctatc tctcttagaa
    24601 ttacacaaga gcaatgcaaa aaataggact ctaatctaag aaattttcta ttttttcgtt
    24661 tcgattacga attgaaatag tggaggcaac aatttttaaa ataggttctc taaatagttg
    24721 acagattcaa agtataatgt tacaattatg ttacaaaaag atttattaac atttcaaaaa
    24781 attacaaaag agtagaaaaa tacaatagaa aacctctcta aaattgatgg ctgttactgt
    24841 attggcttct agtttgctgt taggagcttg tggaaataaa aatgaaacca ctcaaactag
    24901 cagctctgca aagaccagcc aatcatcaag ttctaaagca acttcttcta acaaagaaag
    24961 caagactcaa aaatcttctg atcagtcttc tacaacggca gatcagtcgc aagcggcacc
    25021 agcacctgaa tcaagacaag aacaaacagc tcctagtcaa caagctccat ctcaggtgcc
    25081 ttcaactcat caaggttctc aagcccagtc taaccagtca acttacgacc caacaactga
    25141 ccacaaactt caagacaagc aagctgaaca caacaaacgc taaaagggag ttttaaccat
    25201 ggtcgatggt gatttctcag ctgcagcagg aaactggaag ggagcgagtg gcgaaatcat
    25261 tacggtttca tcagggggta attcacagta gaaactgcag atggaaagaa agaaaacgat
    25321 tctatcagag gctactctta cactcttgat gatggcaagt ataatgctaa aatcggagga
    25381 ggaaaaatca tccaaattac aacaggtgcg gatggtaaag tttcgagtgt tgccttgatt
    25441 caataatagt atctaggatt tcctaggata aaaaaaccgt aaacttcaag ggcactgcac
    25501 cccaataatg ggacaagaga aaaacctctt atgcgaccag ttttctgtac tctacaggag
    25561 actggtcatt taatttctgt tgaattctag tttcattaga atagcagagg aagaaaaatt
    25621 attgcaggaa gttattattc caaatggaag aataaaagga tagcgaaaat aatgtagcaa
    25681 atttcatata caattcatat tagcaggata tactgtagtt aattaaaatt atggagaata
    25741 tagacatgtt taaatcaaat catgagcgaa gaatgcgtta ttccattcgt aaatttagtg
    25801 taggagtagc tagcgtagct gttgccagtc tttttatggg aagtgttgta catgcgacag
    25861 agaaagaggg aagtacccaa gcagccactt cttttaatag gggaaatgga agtcaggcag
    25921 aacaacgtgg agaactcgat tcagaacgag ataaggcaag gaaagaggtc gaggaatatg
    25981 taaaaaaaat agtgggtgag agctatgcaa aatcaactaa aaagcgacat acaaatactg
    26041 tagctctagt taacgagttg aacaacatta agaacgagta tttgaataaa atagttgaat
    26101 caacctcaga aagccaacta cagatactga tgatggagag tcgatcaaaa gtagatgaag
    26161 ctgtgtctaa gtttgagtct aagtttgaaa aggactcatc ttcttcgtca agttcagact
    26221 cttccactaa accagaaact ccgcagccgg aaaatccaga gcatcaaaaa ccaacaactc
    26281 cagctccgga taccaaacca agccctcaac cagaaggcaa gaaaccaagc gtaccagaca
    26341 ttaatcagga aaaagaaaaa gctaagcttg ctgtagcaac ctacatgagc aagattttag
    26401 atgatataca aaaacatcgt cagattgttg ctcttattaa ggagcttgat gagcttaaaa
    26461 agcaagctct ttctgaaatt gataatgtaa ataccaaagt agaaattgaa aatacagtcc
    26521 acaagatatt tgcagacatg gatgcagttg tgactaaatt caaaaaaggc ttaactcagg
    26581 acacaccaaa agaaccaggt aacaaaaaac catctgctcc aaaaccaggt atgcaaccaa
    26641 gtcctcaacc agaggttaaa ccgcagc
//
LOCUS       DAVLTG010000024        25452 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLTG010000024 DAVLTG010000000
VERSION     DAVLTG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.024"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(256..1818)
                     /gene="guaA"
                     /locus_tag="VYN12_001113"
     CDS             complement(256..1818)
                     /gene="guaA"
                     /locus_tag="VYN12_001113"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1415514.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1960..2658
                     /locus_tag="VYN12_001114"
     CDS             1960..2658
                     /locus_tag="VYN12_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1415515.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2701..3597)
                     /locus_tag="VYN12_001115"
     CDS             complement(2701..3597)
                     /locus_tag="VYN12_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1415516.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3606..4541)
                     /locus_tag="VYN12_001116"
     CDS             complement(3606..4541)
                     /locus_tag="VYN12_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1415517.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4538..5263)
                     /locus_tag="VYN12_001117"
     CDS             complement(4538..5263)
                     /locus_tag="VYN12_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1415518.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5347..5982)
                     /locus_tag="VYN12_001118"
     CDS             complement(5347..5982)
                     /locus_tag="VYN12_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1415519.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(5984..6811)
                     /locus_tag="VYN12_001119"
     CDS             complement(5984..6811)
                     /locus_tag="VYN12_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1415520.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6833..7168)
                     /locus_tag="VYN12_001120"
     CDS             complement(6833..7168)
                     /locus_tag="VYN12_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV1415521.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7169..7700)
                     /locus_tag="VYN12_001121"
                     /pseudo
     CDS             complement(7169..7700)
                     /locus_tag="VYN12_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8331..8942
                     /locus_tag="VYN12_001122"
     CDS             8331..8942
                     /locus_tag="VYN12_001122"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1415522.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            8987..9715
                     /gene="rlmB"
                     /locus_tag="VYN12_001123"
     CDS             8987..9715
                     /gene="rlmB"
                     /locus_tag="VYN12_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1415523.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(9754..10665)
                     /gene="trxB"
                     /locus_tag="VYN12_001124"
     CDS             complement(9754..10665)
                     /gene="trxB"
                     /locus_tag="VYN12_001124"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1415524.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10731..10955)
                     /locus_tag="VYN12_001125"
     CDS             complement(10731..10955)
                     /locus_tag="VYN12_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1415525.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11033..11776)
                     /locus_tag="VYN12_001126"
     CDS             complement(11033..11776)
                     /locus_tag="VYN12_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1415526.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11776..12576)
                     /locus_tag="VYN12_001127"
     CDS             complement(11776..12576)
                     /locus_tag="VYN12_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415527.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12734..13090)
                     /locus_tag="VYN12_001128"
     CDS             complement(12734..13090)
                     /locus_tag="VYN12_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1415528.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13103..13615)
                     /locus_tag="VYN12_001129"
     CDS             complement(13103..13615)
                     /locus_tag="VYN12_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1415529.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(13615..14109)
                     /locus_tag="VYN12_001130"
     CDS             complement(13615..14109)
                     /locus_tag="VYN12_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415530.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14244..14690
                     /locus_tag="VYN12_001131"
     CDS             14244..14690
                     /locus_tag="VYN12_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1415531.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14687..15334
                     /locus_tag="VYN12_001132"
     CDS             14687..15334
                     /locus_tag="VYN12_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1415532.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15355..15936)
                     /gene="pdxT"
                     /locus_tag="VYN12_001133"
     CDS             complement(15355..15936)
                     /gene="pdxT"
                     /locus_tag="VYN12_001133"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1415533.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(15937..16812)
                     /gene="pdxS"
                     /locus_tag="VYN12_001134"
     CDS             complement(15937..16812)
                     /gene="pdxS"
                     /locus_tag="VYN12_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1415534.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(16964..18343)
                     /locus_tag="VYN12_001135"
     CDS             complement(16964..18343)
                     /locus_tag="VYN12_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1415535.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18637..19560
                     /locus_tag="VYN12_001136"
     CDS             18637..19560
                     /locus_tag="VYN12_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1415536.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19620..20225
                     /locus_tag="VYN12_001137"
     CDS             19620..20225
                     /locus_tag="VYN12_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1415537.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20244..21488
                     /locus_tag="VYN12_001138"
     CDS             20244..21488
                     /locus_tag="VYN12_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1415538.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21711..21968)
                     /locus_tag="VYN12_001139"
     CDS             complement(21711..21968)
                     /locus_tag="VYN12_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1415539.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22010..24046)
                     /locus_tag="VYN12_001140"
     CDS             complement(22010..24046)
                     /locus_tag="VYN12_001140"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1415540.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24258..25175)
                     /gene="glyQ"
                     /locus_tag="VYN12_001141"
     CDS             complement(24258..25175)
                     /gene="glyQ"
                     /locus_tag="VYN12_001141"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1415541.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
BASE COUNT         7512 a         5721 c         4613 g         7606 t
ORIGIN      
        1 ctccatgaat gatagatacc ttgttatgac gcgcttacca tattagaaag ttggctctct
       61 aattaaatta attctcatta tatatatcaa aagaccgcag tttgaaaact acggtctaat
      121 tttttgtcca aatgtaaacc acttggaact attattcaat ttattctttt tagcaaatgt
      181 tcccgtttta atcccagtta cagtttttaa tcctttgtaa ccgttgattt tacaaagctt
      241 ttaatttttt tgcgattact cccactcaac tgttgcaggt ggtttacttg taatatcgta
      301 gacgatacgg ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac
      361 ttcccatgga attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat
      421 tgcaatcgtg tagtcatacg tacgaccgtc acccataaca ccgactgaac gaacgcctgt
      481 gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg
      541 aagaatagcg tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac
      601 acggatagca agtcctggtc ctgggaatgg ttggcgccat acgatatggt ctggcatacc
      661 aagctctgta ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa
      721 ttcaaactgc atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc
      781 tgtatccgta ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac
      841 atctttgagc ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt
      901 acgtttttgt tcaggatcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc
      961 tgctttgacg atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc
     1021 gcctttacga agaagaccgt ggtccacgaa gatacagatc aattgatcgc caatcgcttt
     1081 ttggagaaga accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg
     1141 tttatcaccg acggtttcac gaattttttt gatctgcatg tcaatgaaat tatccattga
     1201 ccagtcacct ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta
     1261 tacagaatga cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc
     1321 gatggctgcg tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc
     1381 agtaaccgca tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag
     1441 cgctgatggt gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc
     1501 aggaacaact tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa
     1561 aattggaatt ccgagttcga agatttctgg gtcaatatca aatgaaccat cttcatatac
     1621 agaatttgga ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc
     1681 tgaaatttta tggcttttta gttctgaaaa aacaccaata tcacggatac ggcgtgaaat
     1741 cagctggttg tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc
     1801 agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa tatcttttct caatattcta
     1861 tcacaaataa gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt
     1921 ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa
     1981 atccatgatc agataaaaaa ggatattgac gagcaccgtt gggctattgg tgagaggctt
     2041 cccagtgaaa gagatttagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc
     2101 gtatctctat tagtcgaaga aggcgtctta gagcgccatg taggaagcgg cacctttgtt
     2161 tccagtactc gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa
     2221 tcccaaggta aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag
     2281 caagaagttg ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc
     2341 cgctatgccg accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt
     2401 aaggacttta aaaaagaaga aatcaccagt catttcttcc aaaccttgca aaaacatggc
     2461 tatcgtatcg gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc
     2521 cactatttgg aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta
     2581 gaagatggta ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt
     2641 tatcttgaaa ataattagat taccacgcaa aaactctctg tcacggacaa agagtctttt
     2701 ttatttttct aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc
     2761 cataccaaga aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaat
     2821 cgccgatatt ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc
     2881 tcctttaagg aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc
     2941 aaggagaaaa tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagagc
     3001 gaccaaacct gctatgacca ttcccacacc aatgaccaag ctgctccccc actttttaat
     3061 caaggctatg ggtaaaatga tatacagagc ataagtaaag gcagaaaaga gaccccagaa
     3121 cagaccagca ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt
     3181 tcctccgatg gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt
     3241 gatacagcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc
     3301 cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag
     3361 agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc
     3421 ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt
     3481 ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg ttcctgacaa
     3541 cccccaagca ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc
     3601 tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga
     3661 gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga
     3721 cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa
     3781 ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgact taagtctctt
     3841 gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat agtcgaaaat
     3901 aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct
     3961 gcctctacac ctctaactgt tggaacagca agctcaactg acccaaactt ggtttccgtc
     4021 attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt
     4081 ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga
     4141 cttcgtctgt tgagatgaaa catcgcttcc tttaattcag gggctgttaa aagatcacga
     4201 ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct
     4261 ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt
     4321 tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctaggtca
     4381 taaactagtc ctgcctcagt ctgcaagcca tgctctgggt cactctggcc taaatagaac
     4441 tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat tcctgcctcg
     4501 atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt
     4561 caacattatt tctatcttta caaaggaaga atttttcaga cttaggaata aaatattcag
     4621 tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca
     4681 tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa
     4741 aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat
     4801 gtaattccat agaaatctca aatttactta aagaaattga taccaaatct gtttgaaatt
     4861 caggcttttc tcctacttct actagacttg ctctgtcatc ttccgcatga atcaaaatca
     4921 aatcatcttc tggtgagaaa atttcaaaag cgtagccatt ttgaccttta tataatcgat
     4981 gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa
     5041 tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt
     5101 ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta
     5161 acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt ctattattag
     5221 cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt
     5281 tttattttaa aggattttag aattttttac aagatattat gctcaaattt aacattattt
     5341 agctatttag taaagatagt ctttcaaggc ttttgacaaa gcctgataac cagcaatact
     5401 gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca
     5461 atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg
     5521 attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctcc
     5581 ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac
     5641 ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat cctttccgat
     5701 atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc
     5761 aaggttctct agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt
     5821 tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag
     5881 aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttagttt gaattttttc
     5941 ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta
     6001 accagttttc caagacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg
     6061 ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa
     6121 gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat ttcaagtccc
     6181 agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa
     6241 tgcaaccata gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt
     6301 ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa
     6361 agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt
     6421 ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct
     6481 tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga gtcaaagcct
     6541 tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac
     6601 gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca
     6661 tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat
     6721 ctaaaatctt ttccaatcgt gggagatcaa gctgacctct agcatccagc aaggtcccat
     6781 ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc
     6841 acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg
     6901 cttcatctaa ctggtcacga tgactgccat cctctataaa atcttccaaa atataagttt
     6961 ggtaatgata caagggatat ccttctggtg aaaaggttcc ctttggtgtt cgattgaccc
     7021 aagtaggatg agctttagct gttccgatag ttgtttttcc atccttcttc ttgatggtga
     7081 catccatgag aacaccacgt tcagtccact tagcattctc ttcatctccc atagattcaa
     7141 tccgttgatt ggaaatgaag ttccccattt aatagacaat gagcttctta tctccatctt
     7201 tttccaccgt ttcagatggt tcaacaacgt gaggatgccc tccaaagata atatccgctc
     7261 cccaatcgat catcttgtga taaagagctt tttgttcttc agttggttcc aatcgatact
     7321 caacacccat ctgaagcatg ataatggtga tatctgcttc cttctctgcc cgttcaattt
     7381 caaccttcat cttatcttcg tttaaatctg aaagataacg attatagtct tcctgagaaa
     7441 tatactgctc aattccattg aaaccatagg aataggctaa caatgcaacc ttgataccat
     7501 tcacttcctt aatgaccagc ggagcctgaa cacgtggttc gtgcgtataa actccgattg
     7561 gagtgattcc agctttctca ataatatcgg ccgttgaaat aactccctca agttgaaata
     7621 actccctcaa gttgcgaatc caaaatatga ttatgagcta aatccagcac atgataacct
     7681 gcctccttaa tagcatccat aacttcagca ggagcattaa agagaagata acccgctaaa
     7741 taatgatcct tattaatggt tccttcaaaa tcaccaatag ctaaatctgc ttgcttgagc
     7801 caaggagtca catactcaaa attttcatga aagtcatagg taccgtcttc ttttttagct
     7861 gaaaagaaaa gtccatcgtg gtagagcaaa tccccgtggg ccataattct ggcagttttt
     7921 tcctcttcct actcctgaga cttttgctta gtcccctctt gagaaatagt atctcgtttt
     7981 tgactagtca agggattcct tggaagcttt caaacaacaa gaccaagccc ttcataaaac
     8041 gaaaagctaa accaccctga tttcgatttt atcttctttg tatcttcatt ctccctactt
     8101 tcttatgcaa gccttttctt tttattatat cacagataag tatttctttc acaattgaat
     8161 tgaacttccc atctattttc tataaatcct aaatgccata atgctttcaa ttcttgtcat
     8221 tttgtgatat catgtagagg aaatgaacta atccacagtg gcttatttca agtataccac
     8281 ttgggctttg gcagtagcta actgcactaa atataatata aggagagaaa atgtctgcaa
     8341 tagaacgtat tacaaaagct gctcacttaa ttgatatgaa cgatattatc cgtgaaggga
     8401 atcctactct acgcgcgatt gctgaggaag tcactttccc cctatctgac caggaaatca
     8461 tcctaggcga aaagatgatg caattcctta aacattccca agaccctgtc atggctgaaa
     8521 aaatgggact ccgcggtggt gttggactgg ctgctcccca gttagatatc tcaaaacgca
     8581 ttatcgctgt tttggtacct aatattgttg aagaaggcga aactccacag gaagcctacg
     8641 atttggaagc cattatgtac aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc
     8701 ttggcgaagg agaaggttgc ctgtctgttg accgtaacgt gcctggctat gttgttcgcc
     8761 atgcccgcgt tactgttgac tactttgaca aagatggaga aaaacaccgt atcaaactca
     8821 aaggctacaa ctccattgtt gttcagcatg aaattgacca cattaacggt atcatgtttt
     8881 acgatcgcat caatgaaaaa gacccatttg cagttaaaga tggtttactg attcttgaat
     8941 aaagaaaatc ccgttgcaag acggggtttt gtgttataat agaggcatga aaacaaatga
     9001 tattgtctat ggcgtccacg ccgttaccga agccctcctt gcaaatacag gaaacaaact
     9061 ctacctccaa gaagatctcc gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga
     9121 aaagaaggtg tccatttctt ggacatcaaa aaaatctctc tctgagatta ctgaaggtgc
     9181 tgttcatcaa ggttttgttc tacgagtgtc tgaatttgcc tatagcgagc tagattacat
     9241 ccttgcaaaa acacgccaag aagaaaatcc acttctattg attctagatg gtctaaccga
     9301 tccccataat ctgggttcta tcttgcgaac agccgatgcg accaatgttt caggtgtcat
     9361 cattcccaag caccgtgctg tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc
     9421 tattgaacac gttccaattg cccgagtgac aaacctcagt caaaccttag ataaactcaa
     9481 ggatgaaggc ttctggacct ttggaacgga tatgaacggt actccttgcc acaagtggaa
     9541 tacaaaaggg aaaatcgccc tcatcatcgg aaatgaagga aaaggcatct ctagcaacat
     9601 caaaaaacag gtcgatgaaa tgattaccat tccgatgaat ggacatgttc aaagcctcaa
     9661 tgccagtgtt gctgcggcca ttctcatgta cgaagttttt ctaaatagac tataaaaaag
     9721 tttccagtca tctgattgga aactttttta tgattaacta tgttctgtga taaacttgta
     9781 ggcttcttga ccagcgatag ctccatctcc aactgctgtt gttacttggc gaaggtcttt
     9841 caagcgaaca tctccaactg caaagatacc gtcgactgca gtcttcatgt ggctatctgt
     9901 cacaatccag cctgcctgat cttggatatt caattcttta acaaaatcgc taagagggtc
     9961 caaaccaaca tagataaaga caccaccgaa ggcttgctct gtcacttgac ctgttttcac
    10021 attttcaaaa acgacagatt ctactctgtt ttcacccttg atttccttca ctacagaatc
    10081 ccagataaag ctgatttttt cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg
    10141 aagttggtca cgacggtgaa caatggtaac agtcttagca aaacgagtca agaagagggc
    10201 ttcttcaaca gctgaatctc caccaccaac taccaataaa tcttggtcac ggaagaaagc
    10261 accatcacac acagcacagt aagaaacacc acgactgttc agttcttctt ctccaggcac
    10321 tcccaaagga cggtgtttag aaccagttgc tacgataact gtacgtgttt catatgtttg
    10381 gtcatcagtc atcactttct taaaatcacc atggtcttcg acattttcaa cataaccata
    10441 aatgtgctca acaccaagat tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc
    10501 actaatatta gcgtatcctg ggtaattttc gatatcagat gtattattca tctgaccacc
    10561 tggcagacca ccttcaatca aagctacttt tagattgctt cgagcagcat acaaggccgc
    10621 agtcatccct gcaggtccag caccgataat aatagtatcg tacatataga ttccttcttt
    10681 cttgttgtaa ctatctttat tctaactctt tcttgtcaat cacgcaagga ttatgccttg
    10741 aaaacaagaa ttaaactcat aaccgcaaag gataatactg ggacaaccaa gactccaatc
    10801 ataatcatat catagagatg ggcttggcga gccctggctg tcttatcaac tcccgacatg
    10861 gctctcagac caatccaaat ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa
    10921 ctctcgaaat ataaagaaaa tagttgcagt agcatgattt ctctcatttc tatctttttt
    10981 aaagagtaaa ctcagctagt ccaactaact gagttttcct ttatctatta tatcaaatat
    11041 aagtccgttt gtaactagcg aagaattctt ttgtccgctc ttctttaggg gtgtggataa
    11101 tctcatccgg agttccagac tcgatgattt tccccttatc taagaagaga attttatccg
    11161 caacttgggc tacaaaggac atgtcatgac tgaccaaaat catggtctga cctgacttag
    11221 cagcatctgc aatagacttt tctacttcac cgaccaattc tgggtcaagg gctgaagttg
    11281 gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc acgcgctagg gcaacccgtt
    11341 gcttctgtcc acctgataaa tggcgaggat aatggttttc acggtccgaa agcccaacct
    11401 tagccaactc ttccttggca atcttagtcg cttcttggtc agataatttc ttgacaacaa
    11461 ccaagccttc tttcacatta tcaagtgctg ttcgacgttc aaataaatta aactgttgga
    11521 aaaccataga caacttacgg cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat
    11581 caactgaaaa accatcaatc tgaatagagc cactgtcagg tgtttcaaga taattgagac
    11641 tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat caaggctaca acttcccctt
    11701 tttgaatatc caagttcaga tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat
    11761 tcgaaatctt aatcattaac gaaggtctcc tttcacatct gtttgcactg tatcaggtgc
    11821 agaaatagcc atttttctct cgatgaaacg accgaggctt tcaattccga tattgactac
    11881 ccaataaaca agggcaacag agatgaagcg ttcaaaatag cgataatcag ctccacctag
    11941 aatctgagct tgggcaaaga cttccacaac acccgcacta aaagctagag atgttccctt
    12001 ggtcaaaccg atgagggaat taatcaaggt tggagtagct accaccgctg cattaggaat
    12061 aatcactcgt cgataaactt gcgctcgggt catacccaga ctgcgcgccg cctcaatctc
    12121 accaggatta actgagagaa tggctgcacg aatggtttca ctagcataag ctgcctcatt
    12181 aaaggcaaaa gcgacaatcg caaaagctgc agctggaatc gcattgatat tgagaccagt
    12241 tccccattgc tgattgaggg ctttcaaagc caaaggaatt ccgtagtagg tcaacatgag
    12301 ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag aaggcctgca agggatataa
    12361 aatcttgaca cgattgatct tcacaatggc aaaaagaagc gccaaaacca agccaaaaag
    12421 ggcaccacca attgtcaaca taattgttgt tggaagttgt tggacaattc tagggattcc
    12481 atcaaagacc gaacgtaggc taaacagctt gccatccgga atcaattgca tcaagttttg
    12541 gtaccaatct gatgctaaaa tcgttgtaac attcataaaa acatcctctt ctgataatga
    12601 ttcattctac catgcttctg ccgtcaatga aattatttgc tacggtcaga tacagacttt
    12661 gtctacctac tagtttatca tactttgaaa cagggaagtt atatatttta tctatcaaag
    12721 agatagataa aaactatttc agtcccagtt cttcataaga ttttcgataa ccgatttgct
    12781 taacagttcc attttctact aaaatgggcc gttttaacaa cataccgtca cttgctagca
    12841 actcagccgc ttcttggttt gacaaacttc ctaccttatc ttttagccct aattcacggt
    12901 atttgatacc actggtgttg aaaaattgct tcaattcaaa tcctgaggtt tctagccaat
    12961 tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg gacggcttta tagtccacac
    13021 ctaattgatt taattcttgt tttgcttttt tacaagttga acatttgggg tattcgataa
    13081 attctaacat gtgcttctcc ttctatttgt ttatatcttt aaaatctacg ccttcatgct
    13141 ccaagagcca agctttcttt tccactcctg cagcatagcc tgtcagacgc ttgcctgctc
    13201 ccaacacacg atgacaaggt actaggatag accaaggatt gcgtcccact gctccaccaa
    13261 ttgcttgagc agaagccact tgcaggtctt gagcaatttg tccataggtc actgtctgac
    13321 cataaggaat gccctgtaaa tagtcccaaa ctctcttttc aaaattcgtt ccgattggcg
    13381 ccaagagcaa gttggataaa tcctgaggct tgcctttaaa gtaatcatct aagcaagcaa
    13441 taactgggtc taaaatagga tgactaacaa cttcttctat cgtttcatct cctagtcccc
    13501 tctcaaaatg cttctgctcc tgaacccaaa ttccatacaa ataatggtca tcagctacaa
    13561 gtgatagaat accaattggt gaggagtaga ggatttttac atacttcttt tgcattattt
    13621 ctttaatttt tgataggcca agcgttcgcc atctactggc accttaccaa cttgtttaaa
    13681 accaagtttt tcaaaaatat gttgcataac cttgttttca gcatgcgtat ctgagcgaaa
    13741 atcaagataa tcaaaacctt caatcaagcc ctctaagaag gtttgagcaa ctccttttcc
    13801 ctgcacatct gctgccacag caatacggtg aaagactaga tactctgact ctccagcttg
    13861 ccagtttccc tcataaatag cttcataggc ctcctctgga ctcttggtca cagcagcata
    13921 ggctagcagt tctccctctt ccaaggctac gtaggcttgc cctgagatga tatcatcgat
    13981 aataacatct gcatttggat agccattttg ccactggtta ctaccagcat ctgctaaaca
    14041 ttttttggca tcctctatca cctgcatgat ggcatctact tcatttggaa aagctaaacg
    14101 aatttccatc ttttttcctc atttctgact agtttctccc atcatagcat aatttaagtc
    14161 tttctacaag cagttaaaac ttgactttgt atttttgtta ttttataatc tagttatcaa
    14221 aactatataa aaaggagttg aaaatgaaaa ctaccttttc ctacccaaaa tgggcagaaa
    14281 ttccaaacat taacctctat ctggaccagg ttttgctcta tgtcaatcag gtctgcgccc
    14341 ctatctctcc taataaagac aaaggcctaa cagcatctat ggtcaacaat tatgtgaaaa
    14401 atggttacct gacaaagcct gacaaaaaaa aataccaacg ccaacagatt gcccgtttga
    14461 ttgctatcac aaccctcaag tctgtatttt ctattcaaga aatagcccag acacttaata
    14521 ctctacaaac tcaagcaagt tcagaccaac tctacgatgc ttttgtggac tacatgaacc
    14581 aaggaattga cccagctaac cctattatcc aaaccagctg ccaaaccgtt aaactctatc
    14641 atcaaactct agacttaatc gatcatactc aagaggaggt aatccaatga acactagtct
    14701 taaactcagc aaacaactca gttttggaga ggagattgct aatagcgtga cccatgctgt
    14761 gggtgcagtc atcatgctta tcttgctgcc tatttcatcc atctatagtt atgaagcaca
    14821 cggattttta tcctctatcg gcgtttccat tttcgtcatc agtctctttc tcatgttcct
    14881 atcatccacc atttatcact ctatggccta tggttcgacc cacaaatatg ttttgcgaat
    14941 cattgaccat tctatgattt acgttgccat tgccggctca tacacgcccg ttgtcttgac
    15001 cttgatgaat aactggtttg gctatctgat tattgtcatc caatggggaa cgaccatctt
    15061 tggtattctc tataaaatct ttgctaaaaa ggtcaatgag aaatttagcc ttgctcttta
    15121 cctgattatg ggctggttgg ttctggctat cattcctgcc attatcagtc aaacgacacc
    15181 cgttttctgg agtctcatgg taactggcgg gctctgttat acagttggag ctggatttta
    15241 tgccaagaaa aaaccttatt tccacatgat ttggcatctc tttatcctag ctgcgtccgc
    15301 acttcaatac atcgctattg tttattacat gtaaaaaagt tgagaaattc aatctcaact
    15361 tttttcttta cacatattga taaagtactg gtgcaagcgc acatcatcag tcaattctgg
    15421 atgaaaagaa cttaccaaca tatttttttc ttgggctgca acaatttgat tgttcactgt
    15481 tgctaaaatt tctacaccct caccaacact actgataatc ggaccacgga taaaggtcat
    15541 tggaatcttg ccaactccct tacattctgc ttccgtgtag aaacttccta attggcgccc
    15601 ataagcatta cgctcgacca ccatatccat agttcctaga tgactctctt tctgagaagt
    15661 gatttcctta gccagcaaaa ttaagcccgc acaggtccca aacactggta agccagatag
    15721 aatggcttct cggatgggaa gtagcatgtt ctggtcacgt aagagcttgc ccatggttgt
    15781 agactcacca ccaggcaaaa tcaaacccga caagtcactc tgatcttgct gaaaatcatc
    15841 tagatttctg agttctacac tctcgacacc taattgatct agcacttttg catgttctgc
    15901 aaaggcccct tgcaaggcca atattccgat tttcatctat tttcctcgtt cagccatgag
    15961 aatttggatt tcattttcat taataccaac catggcttct cctaaatctt cagagatttg
    16021 agctagaatt tgaggattac ggaagttagt cacagcctta acaatggcac tcgctcgttt
    16081 aacaggatct cctgacttga aaatacctga accgacaaag accccctctg cccctaattg
    16141 catcattaac gcagcatctg ctggcgttgc aacacctcca gcagcgaaat ttacaactgg
    16201 caattttcca tgttcatgaa catattggac caattctaca gggacttgca aatccttggc
    16261 agcaacataa agctcgtcct cacgtaagtt ttgaatgcgg cgaatttcct gattcatcat
    16321 acgcatatga cgaacagctt ggactatatc ccctgtccct ggttctcctt tggtacgaat
    16381 catggaagca ccttcagcga tacgacgcaa ggcttcaccc aaatccttag caccacagac
    16441 aaaaggaact tggaattctt tcttgtccac atggaaacgg tcatcagctg gagatagaac
    16501 ttcactctcg tcgatataat caatttcaat agcctctaaa atctgagctt caacaaaatg
    16561 cccgattctg accttagcca ttactggaat actaaccgct tcttggattt ccttaatcat
    16621 ctttgggtcg ctcatgcggg aaactcctcc agctgcacga atatcagccg gaattcgttc
    16681 caaggccatc acagctgccg caccagcagc ttctgcgata cgagcctgtt caggattctg
    16741 cacatccata ataacaccac ccttgagcat ctgtgccaag tttttattta gttcataacg
    16801 attttcagtc atttgtttta tcctcatcat ttgtattggt agctaccttt tcattttaag
    16861 tcagaacaga atgaagcaca agataaaaaa actataattg tatggggaca gattagctaa
    16921 aaactatctg accttaactt aaggccagat agctcattca tttttatttt tcagccgtaa
    16981 gggcagccat tgtgatgtag ttgtatggtt tgttgaagtg tggcaagaag aagaggtctg
    17041 tcaatgccaa tttatcaatt gtcacatgct cttggatagc aagtgagaac atgtggattc
    17101 ccatgctaat tgcaatatca tgtgaaacca tttgggcacc aagaatttca cggctatctt
    17161 tgtcaaagac aatcttaatt gctacttcat ggttgtcatg tttcatgaat tctggttttt
    17221 gaagatcgtt aaagcctgtt tcagttgcgt tgtaaccagc agctttcgct ttttcaagag
    17281 tcaaaccagt tgaaaccatg tgaagaccgt agattgagat accatttgaa ccttgaacac
    17341 cgattccttc caattcatgt ccacaagcat tgtaggcacc aacgatacca gtgcgaacag
    17401 catttgaagc aagagcgata tagcttgtat ctttacgagc attgtcataa acagtcgcac
    17461 agtcaccaac agcgtaaacg cctgggatag atgtttcttg tttcttgtct acaaggaagg
    17521 caccgttgcg gaagagttcg atcttaccat ctgcaagggc tgtgtttgga cggaaaccaa
    17581 ctgcaaggat aaccatatcc acgtcaaagc tttctttgtc agtaatcaag cgttcaactt
    17641 taccgtcacc ttcgattgct ttaacagttt gacctagagc caagcggatg ttgtgatctt
    17701 ccaagttctt cgccatcatt tgtgtgaagt ctttgtcata gtaaccgttc aagacagtat
    17761 caacgatatc aacaaggaca acttcttttc caagacgttc aaaggcttca gcaagttcaa
    17821 caccgatgta accaccacca acaacggcga tacggtcgag gtgttggctc ttgtcagaaa
    17881 gtttattgat aacttcttca gcattttggt acaatttcac gaattgtacg ttttcaagag
    17941 ttgctttaaa ttcgcggttt cctttaacaa tttcaacacc ttcgattggt ggcaagattg
    18001 gtgtagaacc tgtagcgaaa atcaattttt cgtatgattc tttgtgctct tttccttcaa
    18061 cttccgctgt aactactttg ttatcatagt cgattgaaag aacaggtgag ttcatgtaaa
    18121 ctttagcacc tttagcttcc aatttttctt tatcagaata gaacaagcct tcagcaccgt
    18181 caatttgttc accaatccaa agagccattc cacatcctag gaaagagatg ttagagtttt
    18241 ggtcaaatac aacaatttcg ttctcatttc caaaattatc caacatggta ttgatacatg
    18301 ctgtaccagc gtggttagca ccgactacaa cgattttact cataaaaatt tcctgccttc
    18361 attctaaatt taccttacta gtataccatt taccgttagc gtttacaagg ggggtactat
    18421 tatttcagca ttttttatca aaaataattc cccatttatc ctgttttcaa gcctcatgaa
    18481 ttttatgagc atatttcttg actttttcca aattttgttt gtgaaaattc taactttatg
    18541 gtattataat aacatgaaaa tgaaatgtaa gggcttcaat ttagatgatt atttgatatt
    18601 acaacttatt ttctataaga gaaaggagtt ggtagcttga ctcttcgttc acattctgaa
    18661 cggctaatgg ggactactat cactatttca ttagtggatg agcaagccga tatctttctc
    18721 caaaaatcct ttgacttgct caaagaactt gaataccgct tcaacgccaa tagtcaagaa
    18781 tctgagttga tggaaatcaa ttatcaagca ggaatagccc ccgtcacggt tcatccagac
    18841 ctgtttgagc tgatttcact tgggttagag catagcctag cgctctctag ccacctcaat
    18901 atcagcattg gtcccttaat tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc
    18961 cagcctcaag aaattgaatc ggtgctgcct ctaatcaatc ctcatggtat cgagttagat
    19021 tcttctactt ctactgtgtt tttaaaacag aaaggaatga agatcgatct aggttgttta
    19081 gccaaaggat acagtgcgga taaggttgcc caatttctta ggaaagaggg ggtgacttct
    19141 gccttgatca atctgggagg gaatatcctg accattggaa aaaatcaggc aagaggggat
    19201 aacccatggc aaatcgggat tcaagaccca gccaatccta ggggaaatca tttaatgacc
    19261 atccctgttg tcaataaatc tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc
    19321 gatggacaag attaccatca catttttgac agtcaaacag gatatcctgt tgaaacggaa
    19381 ctagcgagtc taacaatcat ctctgataaa tcagtcgatg gcgaaatctg gacgactcga
    19441 ctctttggag aaagacctgc ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa
    19501 gtcatcctca tcgataaaga aggccaccta agctgttctt caggaattcc tactctatag
    19561 agacaactgt ttcaatggaa ttttaaaatt gtattatgta aaaagagaaa ggaaatctca
    19621 tgttaaaact tattgctatt gttggaacaa attcaaaacg ttctacaaac cgtcaattgc
    19681 ttcaatacat gcaaaaacac ttttctgaca aagctgaaat tgagcttgtt gaaatcaagg
    19741 ccattcctgt cttcaacaaa ccagctgaca agcaagtacc tgctgaaata ttggaaattg
    19801 ctgctaaaat cgaagaggca gatggcgtta ttatcggtac tcctgagtat gatcactcta
    19861 ttccagctgt tttgatgagc gctcttgctt ggttgtctta tggtatttac ccacttttga
    19921 acaaaccaat catgattaca ggtgcttctt acggtacgct tggttcatct cgtgcccaat
    19981 tgcaacttcg tcaaatcttg aatgctcctg aaatcaaggc aaatgttctt ccagatgaat
    20041 tcttgctctc acactctctt caagcattta acccaagtgg cgacttggtt gaccttgatg
    20101 ttatcaagaa attggatgcc atctttgatg acttccgtat ctttgtaaaa atcacagaaa
    20161 aattacgtaa tgcacaagaa ttacttcgca aagatgctga agactttgac tgggaaaatt
    20221 tgtaagatag gagaccaaaa agaatgaaat ttgttggact tgttggatca aactacgatc
    20281 aatcatataa ccgtaagctc ttggaattta tccgtcgcta cttcaaactc aaatttgaat
    20341 tagaagttct tgaaattgac gaagttccaa tgtttaacca agatgaaaaa tgggatgaaa
    20401 gtttccaatt acgttattta tataacaaaa ttactcgtgc agatggtgtt atcattgcta
    20461 ctcctgagca taaccacact atctcagctt cactcaaatc tgtacttgaa tggctttcat
    20521 acgaagttca tccatttgaa aacaagcctg ttatgattgt gggtgcatca tactatgacc
    20581 aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg
    20641 cctacacgct tccaggtaac gaattccttc ttggtaaagc taaggaagct tttgataaca
    20701 acggaaatat caccaacgaa ggcactgtta aattccttga aacttgctta gataactttg
    20761 ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa accaatcgaa tcagaagact
    20821 tggattgtgg aaaaccaatc gctacaacca tcacagaagt tgaccctgac gatccagaat
    20881 gggtagaaaa agttgcagca atcactggtg ctgtttctgg tgatacctat gtcaaattgg
    20941 accacggtat cctaacagtt aaccaaattg atatgttctt gaaagctatg ccatttgaat
    21001 tgacatacgc tgacgacaac aaccaattcc tctactacaa caacgctcac caagatccag
    21061 acactatgtt cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg actgttcatg
    21121 gttctcttcc accagcacgt atgaagaacg tagagtgggt tatcggaaca cttcgcaacg
    21181 gaaaccaaga atacgtccgt acgatcgttc caggttctcc tgcaggtgtt atcaacactc
    21241 acaactacca agcaatgtac tatcctgatg gatcatacgc tggtatcaat gaaatcgtct
    21301 ttaacttcca accatggctt gactggtacc taaaagagac tggtcaacgt ttggtgggtg
    21361 gtagcggacc atttgctcct gctgccggag gtcatggaga cgccgatgct acttctggcg
    21421 cttctgattc aggggatgct gggggccacg gtggtgacgc agacgctaca gccggtgcaa
    21481 gttactaatg atagttttta ggaaccatta tggttccttt tttagcgaaa aaagactagc
    21541 aaacacaaac tgctagtctc tttgttatcg tttcatctat ctttgttaaa agaaagagta
    21601 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttaagt
    21661 acggcaaggt gaagctgacg tggtttgaat ttgattttcg aagagtatta ttatgaattt
    21721 gggtcatcaa gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct
    21781 ggtgtaacat cgtttccttc ttcgtccaca attttgattc cttcaatgtg gtgacgaaca
    21841 gcgcggcgat aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct
    21901 ggtgttaagc cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc
    21961 ggatccattt cttctccttt gtaataagat aaagtccgtt tatcaaattt tatttagtgt
    22021 taatttggtt aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca
    22081 aacgattttg acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat
    22141 caatgactgg gctaagcgca aagagttgtt tcaattgctg acttgcaggt cctgataaaa
    22201 cgagtgtttc tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat
    22261 caactgtagc aaccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa
    22321 cagatggttt aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca
    22381 tatctgccac aacaaagttt gaacctgcaa gaactgcttc tttgatatct tttggagtag
    22441 agcccatcat cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat
    22501 aagtcaaact gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt
    22561 gccaaccaaa ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag
    22621 ggtcattaga acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt
    22681 tgtctgcaat ggctagaact gcgccgacct tgctctctgg aagttctcct tcagctgatg
    22741 taggcatgta gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg
    22801 tgtatttttc acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca
    22861 agtcaaactt gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac
    22921 cagctttttc tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg
    22981 aaccaatctt ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca
    23041 atttttggtc ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt
    23101 catttccttt gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt
    23161 ttggcaagag ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag
    23221 aagtcaccaa gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg
    23281 cagttgggta ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac
    23341 gtacaccatg ttttgcctca atttccttga tttggtcaac aatcatttgc tcacgttcac
    23401 atggatctgc gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa
    23461 ttttggtttc tttccccaag aaacgatggc cacggctcac acgacttccc ttgatatcaa
    23521 ggaaatccaa gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga
    23581 tgtattcaaa gctatttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga
    23641 catctacaac accaggaaca atggcttcaa ctgcttgacc aacttcttcc ttagtgacat
    23701 agacatattc ttcacccttg atttcacgga attcgatatc ttcaacagtc aaacctttcc
    23761 cacggacaaa tccttgagct gctttggtga agtttccatc actatccaag gcaattttct
    23821 ttgctggtcc cttgaaatct tctgtcaaat cagactgttt gtctgataaa ccagtcacac
    23881 gaacagccaa acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcggtttt
    23941 ccttgaggaa ggctgccatt ttttcgccta gttgtttttc acttggtgtg acaacatagg
    24001 ctggtaattc ttcaagaccg agttctacta ataagttttt tgtcatgttt tttctccgaa
    24061 aagtatcttt ttattttcca gtttgcctta tgtgattggc acgcaagcaa ccaacttcgt
    24121 tgtttcattg ctaaaattgg agccaaaagt ctccaatttt gcctagtatc cttagtttca
    24181 ctaaggatac cttcatcact gcggcaactg gctcagggct cactctgttc gcccattttc
    24241 gtaatttgtc actctcttta ttctgcgtct tctgctagga gtttagctct tgtttcttca
    24301 tccaaaagtg ggtagcctag gcgtttgcgt tctgcgacaa aggttttggc tacgacacgg
    24361 gccaagttac ggatacgagc gatatagcct gcacgctctg ttacagatac ggcaccacgc
    24421 gcgtcaagca gattaaaggt atgtgaacat ttgagaacat agtcataggc agggtgtacc
    24481 aagccttctt ctaatgcacg accagcttct ttttcaaact tatcaaaatt ttcaagcaac
    24541 atttcttggt ccgaaatttc aaatgaatat tttgagtgct catactcagg ctggataaag
    24601 atttctccgt attttacacc atcagcccac tcgatatcat agacagagtc aacttcttga
    24661 atgtaagaag ccaaacgctc caaaccatag gtaacttccg cagtcacagg accagttgcc
    24721 aatccaccga cttgttggaa ataagtaaac tgagtgattt ccatcccatc aagccaaact
    24781 tcccaaccaa gaccagctga accagtcgat ggattttccc agttgtcctc aacgaaacga
    24841 atatcgtgtt ccaaaggatt gatacccaat ttttccaaag actcaaggta aagctcttgg
    24901 atatttgatg gagaaggttt cataaccact tggaattggt ggtgttggta aaggcggtta
    24961 gggttttccc cataacgacc gtcagcagga cgacgtgatg gctctacata agccgcattc
    25021 catggctcag gtccgatagc acgaaggaaa gtgtaaggac tcattgttcc agcacctttt
    25081 tcgttgtcat aagcctgcat aagcatacaa ccttggtcat tccaaaattg ttgcaaagta
    25141 aggatgattt cctggaaagt caatttttta gacattattt actcctttta attaaaaaaa
    25201 tttgttttct ttatttcatt ttcttttaaa actattattg agaaattatt tctctttttt
    25261 tgcatgttta tcaatttatc aatactacaa aagacttcat ttgttgttac aagtattagt
    25321 tttttatatg gttttctatt agtttcaatt gaatagttat ccgataattc atataatttc
    25381 gtaatatacc tatctaacac tgaactccca atattatttt gcaaatattt aatctcaaag
    25441 ataatatctt ta
//
LOCUS       DAVLTG010000025        24638 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLTG010000025 DAVLTG010000000
VERSION     DAVLTG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.025"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            35..1561
                     /locus_tag="VYN12_001142"
     CDS             35..1561
                     /locus_tag="VYN12_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1415542.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYV
                     QNAWVGNYYLKSGGYMAKSEWIYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAK
                     SEWVYDSNYKSYYYLTSEGSYARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK
                     "
     gene            1648..2566
                     /locus_tag="VYN12_001143"
                     /pseudo
     CDS             1648..2566
                     /locus_tag="VYN12_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            2701..3660
                     /locus_tag="VYN12_001144"
     CDS             2701..3660
                     /locus_tag="VYN12_001144"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1415543.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            3757..4596
                     /locus_tag="VYN12_001145"
     CDS             3757..4596
                     /locus_tag="VYN12_001145"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1415544.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLFKQLEANPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(4644..4814)
                     /locus_tag="VYN12_001146"
     CDS             complement(4644..4814)
                     /locus_tag="VYN12_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1415545.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            4935..5819
                     /gene="miaA"
                     /locus_tag="VYN12_001147"
     CDS             4935..5819
                     /gene="miaA"
                     /locus_tag="VYN12_001147"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1415546.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            5812..7050
                     /gene="hflX"
                     /locus_tag="VYN12_001148"
     CDS             5812..7050
                     /gene="hflX"
                     /locus_tag="VYN12_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1415547.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            7043..7666
                     /locus_tag="VYN12_001149"
     CDS             7043..7666
                     /locus_tag="VYN12_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1415548.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            7681..8610
                     /locus_tag="VYN12_001150"
     CDS             7681..8610
                     /locus_tag="VYN12_001150"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1415549.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            8631..9386
                     /locus_tag="VYN12_001151"
     CDS             8631..9386
                     /locus_tag="VYN12_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1415550.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(9440..10348)
                     /locus_tag="VYN12_001152"
     CDS             complement(9440..10348)
                     /locus_tag="VYN12_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1415551.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            10412..10681
                     /locus_tag="VYN12_001153"
     CDS             10412..10681
                     /locus_tag="VYN12_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1415552.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            10681..11061
                     /locus_tag="VYN12_001154"
     CDS             10681..11061
                     /locus_tag="VYN12_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1415553.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            11150..11377
                     /locus_tag="VYN12_001155"
                     /pseudo
     CDS             11150..11377
                     /locus_tag="VYN12_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11417..12142)
                     /locus_tag="VYN12_001156"
     CDS             complement(11417..12142)
                     /locus_tag="VYN12_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV1415554.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            12304..14145
                     /gene="typA"
                     /locus_tag="VYN12_001157"
     CDS             12304..14145
                     /gene="typA"
                     /locus_tag="VYN12_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1415555.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            14165..14419
                     /locus_tag="VYN12_001158"
     CDS             14165..14419
                     /locus_tag="VYN12_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1415556.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            14784..15083
                     /locus_tag="VYN12_001159"
                     /pseudo
     CDS             14784..15083
                     /locus_tag="VYN12_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            15166..17187
                     /locus_tag="VYN12_001160"
                     /pseudo
     CDS             15166..17187
                     /locus_tag="VYN12_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            17189..17830
                     /locus_tag="VYN12_001161"
     CDS             17189..17830
                     /locus_tag="VYN12_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415557.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            17934..19286
                     /locus_tag="VYN12_001162"
     CDS             17934..19286
                     /locus_tag="VYN12_001162"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1415558.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            19290..20348
                     /locus_tag="VYN12_001163"
     CDS             19290..20348
                     /locus_tag="VYN12_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1415559.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            20358..21566
                     /gene="divIB"
                     /locus_tag="VYN12_001164"
     CDS             20358..21566
                     /gene="divIB"
                     /locus_tag="VYN12_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1415560.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEKEE
                     PESKEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYAT
                     MKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQF
                     PTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIK
                     VFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSK
                     IKPQLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNR
                     NQTTQRSSRR"
     gene            21799..22500
                     /gene="pyrF"
                     /locus_tag="VYN12_001165"
     CDS             21799..22500
                     /gene="pyrF"
                     /locus_tag="VYN12_001165"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1415561.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            22534..23166
                     /locus_tag="VYN12_001166"
     CDS             22534..23166
                     /locus_tag="VYN12_001166"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1415562.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            23346..23749
                     /locus_tag="VYN12_001167"
                     /pseudo
     CDS             23346..23749
                     /locus_tag="VYN12_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            23845..24609
                     /locus_tag="VYN12_001168"
     CDS             23845..24609
                     /locus_tag="VYN12_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415563.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
BASE COUNT         7472 a         4469 c         5441 g         7256 t
ORIGIN      
        1 accgtaaaca atagaaattt aaaggagatt tttgatgaaa tcaaaaatag ttttgggagc
       61 ttcgctagcg atcgcaacac ttagcttagt atctcttgtc gagattgaag gactctcacc
      121 gtttttaata gagaatgtta gcgcaaatac tcattctgca aataaagtta ttaatcataa
      181 agtaagtatt tacttagaaa atgctgatga aggtaaaggt ctaactgtaa acttttcaac
      241 agacagtgtt agtccaaatt tatttgatga gttcgaaaaa aagagtggaa ttacaataac
      301 tactatgtta gtgaatgcta agacaggtga agttgtagaa aaaagattaa caccaagcgt
      361 ttttttacgt tccaatgatt taaccagtgg gaccatatct tcgtttattt ttagtgaata
      421 tcctgatgga gaatataaat atgttgtgtc taaaggagac tttatcgatc ctaagactca
      481 gtttaaacat cagtatagag gagaatctcc agtttttaga atacgtaatc gaaaatatgt
      541 ggagttggga acaactgata aaaaattaga tgaaagacgt gataatagcg tttataaaga
      601 tggggttgtt gaacacaagg taaatttaag tttaacaagt tatcaaggag gtaatggagt
      661 tactgcaatt ttttcaactg atagtgttaa ctctaactta cttaattctt ttggtgaaaa
      721 ggctaaaaaa gttttgatta ggtctaagtt aattaatgtt aagactggcg aggttattga
      781 tgaaacgttt tctccaaaag taagtttaac ctctaaaatt ttgaaaagtg gttctacagc
      841 agtattttat tttatagatt taactgatgg cgaatataaa tatgttgcgt atgaaagcca
      901 gcaatatact gatcctcaaa caacattgac tcatcagtat agaggagaat ctcctatttt
      961 tagtatcaaa gatggaaaat tttctggttt agtatctgcc tcaaaaccag acgaaaaccc
     1021 gaagccaacg ccaaaaccgg atgagaaacc aaaaccttca gcaccacaac aggagaaaac
     1081 aaaacctaca gttcagtctg gttgggtagg ttcatcttat tatcaaaatg gtaaaaaagt
     1141 cactagtaag tggatttttg ataaaaaata taattcatac ttctatctag atgcatcagg
     1201 aaattatgtt caaaacgctt gggtaggtaa ctattatctc aaatcaggcg gatacatggc
     1261 taaaagtgag tggatttatg ataagaacta tggttcatac tactatctaa catcagaagg
     1321 cagctacgct cgtaacactt ggtcaggcaa ttattatttg aagtcaaatg gtaagatggc
     1381 taaaagtgag tgggtatacg atagtaacta caaatcatat tactacttga catcagaagg
     1441 aagttatgct cgtaacactt gggtaggcaa ttactatctt aaatcaaacg gtaaaatggc
     1501 tgttaatgaa cgtacaccag atggttatcg tgtagatggt tcaggtaaat gggttaaata
     1561 agaaactaaa aaataggata ataggtaata tcagatgaat aaaaaaaatt attttcatgt
     1621 gctttagcat tttcaacgat tggaacattg tcaacgattg ataaatcagg agttcttcct
     1681 ttttcagcgc aaacggtgca ggctgacata caaacgctta ccccaatggc aaaatattat
     1741 attattcttc cgaaggatgc agaaatatat aaaacttgga gaggtactgt caatattccc
     1801 attattgatg ctacaaaaac tactccagaa ttatcttatt tcaaagaaga tcatcgcaac
     1861 tatatagcta atgagaataa gtctggtgcc aattacatag agtggaaggg aacagtagaa
     1921 gagtttaaag aggccattaa gaagttgact gataaaaaat caactactgc aacaccaaaa
     1981 aaggatgaaa agccaacacc aaaaccggat gagaagccaa aaccaacacc tacagttcag
     2041 tctggttggg taggttcatc ctattatcaa gatggtaaaa aagtcattag taagtggatt
     2101 tttgataaaa aatataattc atacttctat ctagatgcat caggaaatta tgttcaaaac
     2161 gcttgggtag gtaactatta tcttaaatca ggcggataca tggctaaagg tgaatgggtt
     2221 tatgttgcca cctatcaagc ttggtattat ttgacatcag atggttctta tgcttacagt
     2281 acatggcaag gaaattacta tctaaaatcg gatggtaaaa tggctgtcaa tgaatgggtt
     2341 gatggtggac gttattatgt tggcgctgac ggagtttgga aggaaggtca agcaagtaca
     2401 gcttcttcta gtaatgatag caatagtgaa tattctgctg ctttaggaaa ggcaaaaagt
     2461 tataattcgt tattccacat gtcaaaaaaa acgtatgtat agacaattaa cttctgattt
     2521 tgataaattt tcaaatgatg cagctcaata tgccattgat cattagatga ttaacagata
     2581 ctggtaggcg aaaaaattcc ttataattca tttacgcaaa cctttgcata agtgaatgga
     2641 ttttgatata ctagtactgt aagcattttc aattactaca caatgaaaaa ggagaatatg
     2701 atgagtcaaa agattattgg gattgacctt ggtggaactt ctatcaaatt tgcaatctta
     2761 acaacagcag gagaaatcca aggaaaatgg tcaatcaaga ccaacatttt ggatgaggga
     2821 agtcatatcg ttgatgatat gattgagtct attcaacatc gtttggactt gcttggattg
     2881 gcagcagcgg acttccaagg cattggaatg ggatcaccag gtgtggttga ccgtgacaaa
     2941 gggactgtta tcggtgccta caacttgaac tggaaaaccc ttcaaccaat caaacaaaag
     3001 attgaaaaag ctttgggcat tccatttttc atcgataatg atgccaacgt agcagctctt
     3061 ggtgagcgct ggatgggtgc tggagataac caaccagacg ttgtctttat gacactcggt
     3121 actggtgttg gtggtggtat tgtcgcagaa ggcaaattgc ttcatggtgt tgctggtgca
     3181 gcaggtgaac ttggtcatat cactgttgac tttgaccaac caatctcatg tacttgtggt
     3241 aaaaaaggct gccttgagac agttgcttca gcaacaggga ttgtcaactt gactcgtcgc
     3301 tatgccgatg aatacgaagg cgatgcagcc ttgaaacgcc tgattgataa cggagaagaa
     3361 gtaactgcta agactgtctt tgatctcgca aaagaaggag acgaccttgc tttgattgtt
     3421 taccgtaact tctcacgtta cttgggaatc gcttgtgcta acattggttc aatcctaaac
     3481 ccatcaacaa tcgtcatcgg tggtggtgtg tcagctgcgg gagaattcct tctacaaggt
     3541 gttcaaaaag tttacgatga aaatagtttc ccacaagtac gcacatctac taaattagct
     3601 cttgcaactc taggaaatga cgctggagtt atcggagcag catcacttgt attgcaataa
     3661 gataatgaga gaggaaaatg ctaacctaga gttagtaatg ttcctctttt attttttatg
     3721 ctatactagt taggacaatg aatgaggtga aacgaaatga caaaagcaga tacgattttt
     3781 aaagagaata ttgaacgcat tctaaaggaa ggtgttttct cagagcaggc tcgtcctaag
     3841 tacaaggatg ggactgttgc taattccaag tatgtaactg gtgccttttc cgagtacgac
     3901 ttatctaaag gagaatttcc tatcacaacc ttgcgtccca ttgcaatcaa atccgccatc
     3961 aaagaagttc tctggattta ccaagaccag tcaaatagct tagaggtact taatgataag
     4021 tacaatgttc actactggaa tgactgggaa gtgggggata caggaactat tggtgaacgc
     4081 tacggtgctg ttgttaagaa acacgacatc atcaacaagc ttttcaaaca gttggaagcc
     4141 aacccttgga accgccgcaa tatcatttcg ctctgggatt accaagcttt cgaagaaaca
     4201 gatgggctac tcccatgtgc ctttcagacc atgtttgatg tccgccgtat agatggagaa
     4261 atctatctgg atgcgacctt gacccagcgc tcgaatgaca tgctagtagc ccaccacatc
     4321 aacgctatgc agtatgtggc tttgcagatg atgattgcca agcattttgg ctggaaggtt
     4381 ggaaagttct tctacttcat caacaacctc catatctatg acaatcaatt tgaacaagct
     4441 caggaattac tccgtcgtga accgtcaaac tgccaaccac gtttggtttt gaatgttcct
     4501 gatggaacta atttctttga tatcaaagca gaagattttg aattggtgga ttatgaccct
     4561 gttaagccgc agttgaagtt tgacctagct atttaaaaga atagaaaaaa gaagttgaga
     4621 ataatcccaa cttcttttgt ttcttaacgt gatacgcggc gacgagctgc ttttttacgg
     4681 ttttcttcga tgaaagctgc tttttgctct tctggttcga ttactttctt tttaaatgcg
     4741 tatactgcac ctgcaacggc agcgacagtt cctgcgacac ctgttacaag acctttagcg
     4801 aatcctttag ccatgagtct tcctccttta tattctcaat cagccagcct cctcaagagg
     4861 tcacattttt ctgactgacc tttttgtgtt ataataatag taacgaaaaa atgggaattt
     4921 ttcaaggaaa aaagatgaaa acaaaaataa ttgtgattgt tggaccgact gctgttggaa
     4981 agacggctct agctattgaa gttgcaaagc gttttaatgg cgaagtggtt agtggagata
     5041 gccaacaagt ctatcgagga cttgatattg ggacggccaa ggctagtcca gaagagcagg
     5101 cagctgttcc tcatcattta atcgatgtta gagagataac cgagtcttac tcggcttttg
     5161 attttgtttc agaagctaag atgactattg aggatattca gagccgtggc aagctagcca
     5221 ttatcgccgg tgggactgga ctttatatcc agagcttgct agaaggttac cacctaggtg
     5281 gggagactcc tcatgaggag attttagctt atcgagctag tttggagcca tattcagatg
     5341 aggaattagc ccatttggtg gagcaagcag gccttgagat tccccagttt aatcgtcgtc
     5401 gtgctatgcg tgccttagaa attgcccatt ttggtcagga tttggaaaat caagagatct
     5461 tgtatgaacc gctgattatc tgcttggatg atgaacgtag tcaactttat gagcgtatca
     5521 accaccgagt ggatttgatg tttgaggctg ggcttttgga tgaggccaag tggctgtttg
     5581 accattcccc taatgtacag gctgctaaag gaattggcta taaggaactc tttccttatt
     5641 tccgtggaga gcagaccttt gaggaagctc gtgagagtct taaacaggcg acccgtcgtt
     5701 ttgccaagcg tcagctgacc tggttccgta atcgcatgca ggtcaccttt tatcagattg
     5761 gagaatctgg tgtacaagac cgcattttaa gccagataga ggagttttta gatgattgaa
     5821 acggagaaaa aagaggagcg agtcctgctg attggtgtgg aattgcaggg tatggacagt
     5881 tttgacctct ccatggaaga attggctagt ttagcgaaaa cggcaggggc agtcgttgta
     5941 gatagctaca gacaaaaacg tgaaaaatat gattccaaga ccttcgtcgg ctctggtaag
     6001 ttggaagaga ttgcgcttat ggtggatgca gaagaaatca ctactgtcat cgtcaacaat
     6061 cgtctgaccc caaggcagaa tgtcaatcta gaggaagttc tcggtgttaa ggtcattgac
     6121 cgtatgcagt tgattttgga tatctttgcc atgcgggctc gaagccatga agggaagctc
     6181 caagtccacc tagcccaact caaatacctc ttgcctcgct tggttggtca ggggattatg
     6241 ctcagccgtc aggcaggggg aattggttcc cgtggtcctg gtgaaagcca actggagctg
     6301 aaccgtcgta gcgttcgcaa tcaaatcacg gatatcgagc gccagcttaa ggtggttgag
     6361 aaaaatcgtg cgactgtcag agaaaaacgt ttggagtcta gcacttttaa gattggtttg
     6421 attggttata ccaatgctgg gaaatcaact atcatgaaca tcttgaccag taagacccag
     6481 tatgaagcag atgagctctt tgcgactctg gatgcgacaa ccaagagtat tcatctggga
     6541 ggcaacctcc aagtaacttt gacagatacc gttggcttta tccaagattt gccgacagag
     6601 ttggtgtcca gtttcaagtc aaccttggaa gaaagcaagc atgtggacct tctggttcat
     6661 gttatcgatg ctagcaatcc ttaccacgag gagcatgaaa aaacggttct ctccatcatg
     6721 aaagacctgg acatggaaga tattcctcac ttgacgcttt ataataaagc ggatttggtg
     6781 gaggatttca cgcctaccca aacgccatat accctcattt ctgccaagtc tgaggacagt
     6841 cgtgaaaact tgcaagcatt attgctagat aagattaagg aaatttttga agcatttacc
     6901 ctgcgagtgc ctttttcaaa gtcctacaag attcatgatt tagagagtgt tgcaattctg
     6961 gaagaacgtg attatcagga agacggcgaa gtgattacag gctacatttc cgagaaaaat
     7021 aaatggaggt tagaagaatt ttatgactga tattaaaact ttggctctaa agtatggagg
     7081 ttatacaagt ctggacaagg tctatctgga tcagcttcta gctggtaaaa cagatcagga
     7141 gcagttaaca cttattacac ctccgccaag tgttgttaat gcctactttg cagaactcta
     7201 tcagaaaaag agtcctcagg ctgcgacgga ttattttgca gaactcagtc aggaactgaa
     7261 tctttacaat actgagccaa gtttcaccct agaaaataag ccttttattc ggcttaatct
     7321 gtctggtaaa tcctttggtt tttgttatga gagtgacggc cttggtcgga ttttctttga
     7381 aaatgaggag aaaatctcgg atgacttgct ctttgaaatt gcgcaaattt tcccccatca
     7441 attagtcttt gaagagtctg gtaagattta catgaagcct gtcgaggacg aggaagttat
     7501 cagcctagaa agtctcacag ctttgactga tttggaaaga ttggctgatg gtcgaaaacg
     7561 tctcaaaggc tacagccaag aggatttatt gcaagaagct gctgcttttt ctggcaaacg
     7621 ctatttccga tcggaaaacc gcacagccat gttatatatt gattaattag aaagtatcga
     7681 atggatattc aatttttagg aacgggggct ggtcagccct ctaaagcccg caacgtttca
     7741 agtctcgccc tgaaactttt ggatgagatt aacgaagttt ggctctttga ctgtggagaa
     7801 ggtacgcaaa atcgcattct ggaaaccaca attcgaccac gtaaggtcag caaaatcttt
     7861 attacccatc tgcatggaga ccacattttt ggtttgccag gtttcctttc tagccgtgcc
     7921 tttcaggcca atgaagagca gacagatttg gaaatctacg gacctcaagg aatcaagtca
     7981 tttgtcttaa ccagccttcg tgtgtcaggt tctcgtctgc cctaccgcat tcatttccat
     8041 gagtttgacc aagattctct gggtaaaatt cttgaaaccg ataaattcac tgtgtatgca
     8101 gaggagctgg accacactat tttctgtgtt ggctatcgtg tcatgcaaaa ggatctagaa
     8161 gggacgctgg atgctgaaaa actcaaggct gctggtgttc cgttcggccc gctttttggt
     8221 aaaatcaaaa acggccagga tcttgttttg gaagacggaa ctgaaatcaa ggcagcagac
     8281 tatatctcag cgccacgtcc aggtaagatt atcactattt taggagacac tcgaaaaacg
     8341 ggtgccagtg tgcgtctggc tgtcaatgca gatgtcctag ttcatgagtc cacttatggc
     8401 aagggtgatg aaaaaattgc tcgtaaccat ggtcactcaa ctaatatgca agctgcacaa
     8461 gtagcggtag aagcaggtgc caaacgcctc ctactcaacc atatcagtgc ccgtttcctc
     8521 tcaaaagata ttagcaaact caagaaagac gctgccacaa tttttgaaaa tgtccatgtg
     8581 gtcaaagact tggaagaagt ggaaatctag cagtcacaga aaggataagt atgcctacta
     8641 ttctcattac cggagctagc ggtggtctag ctcaagaaat ggtcaaactc ctgcccaatg
     8701 accaactcat cttgcttggt agaaataagg aaaaattagc ccaactctac ggaaattatt
     8761 cccatgcaga attgattgaa attgatatta ccgacgattc agccctagaa gctctggtaa
     8821 ctgatcttta tctccgctat ggcaagattg atgtcttgat taacaacgct ggttacggga
     8881 tttttgaggg atttgaccag attgctgata aagatattca ccagatgttt gaggtcaata
     8941 cctttgccct gatgaatctg tctcgtcacc ttgcggctcg tatgaaggaa agcagcaaag
     9001 ggcatatcat caacatcgtc agcatggcag gtctaatagc tactggcaag tctagtcttt
     9061 actcagcgac caagtttgcg gctattggtt tttcaaatgc tctgcgactc gaacttatgc
     9121 cctatggagt ctatgtgaca acagtcaatc caggtccaat ccgaacagga tttttcgacc
     9181 aagccgaccc agatggaact tatcttaaat cggttgaccg cttcctgcta gaaccagatg
     9241 cagtggctaa aaagattgtc aagattatag gaaaaaacaa acgagaactc aatctcccga
     9301 ttttgttgaa cctagctcat aagttttata ccctctttcc taagctagct gataagttgg
     9361 caggggaaac ttttaattat aagtaaaaag aaccaatgtg caggttgttg ctagcctaca
     9421 tattggttct tatcatttct caactatcaa actgaacttc ttctaggaga tagtctataa
     9481 agcgttcgcc catcttagat aggctggttt tctcatgctg gatatagacc agctcgatcg
     9541 ggtcatcaat atccagtggg atagaaacga tattgtctcc gtttaggttg ctgttcaaaa
     9601 tccctgtcgc aatggtataa ccatccaaac caatcaagag attaaagagg gtggcacggt
     9661 cactgaccac aatggatttc ttgtggtgtt cttgagaaag aatctcttct gaaaagtaga
     9721 aggagttgtg cgtcccttgg tcatagctga ggtaagggaa attctccaaa tcagacagtt
     9781 tcaccttgtc tttctttgcc agagggttgg tcttgctgac aaagatatgt ggttgcgctg
     9841 tgaagagatg gtgggctagc aggtgattgt catccagcat cttggttaaa acatcacggt
     9901 tgtaactgtt taagaagagg accccgacct cactgcggaa gttcttgacg tcgtcgataa
     9961 tctcccaagt ccgagtttca cgaaggaaga gttcgtattt ctccatatcg cttttcttga
    10021 gcaaagagac aaaggcattg accacaaagg catagtgttg agacgaaacg ctaaatagtt
    10081 cgcggtgggc gacaggattt ttatagcgtt cctccagaag ctgggtctgc tcgacaacct
    10141 gacgggcata agagagaaac tccatcccat cacgggtcaa ggtgattccc ttgggattgc
    10201 ggataaagat ctcaatgccc atttcatttt ccaaatctcg cactgcattg gagagacttg
    10261 gctgagtgat aaagagttgc ttggctgcct cattcatgga gccagtttcg acgattttga
    10321 taatataatg taattgttga attctcatgt ttttattgta ccatacttgc cttagaatcg
    10381 ctaaagaaga taggaaaata aggagcattg tgtgagtctc ttcttgaaaa aaacacaaaa
    10441 ttttgctaga atgagtctta tgaaaacatt ctatgatgtg cagcaattcc tcaaacgatt
    10501 tggtattatt gtttacatgg gaaaacgctt atatgatatt gaactgatga agttggaact
    10561 atctcggatt tacgatgcag ggttgatgga taaattagac tatctagagg cagaagcagt
    10621 tcttcgcaga gagcacaagg tagaattgga ttatattgag aaaaatggag aaaagaacta
    10681 atggttactt ggattttgtg ggcacttata ctagcaatgt tggcgtggat gggctttaac
    10741 tatcttcgta ttcgccgtgc ggctaaaatt gtggacaatg aggagtttga agccttgatt
    10801 cgtacgggtc aattgattga tttgcgcgac ccagcagaat tccacagaaa acatatcctt
    10861 ggtgcacgca atattccttc aagtcagttg aaaactagtc ttgcagccct tcgtaaagat
    10921 aaacctgtcc ttctctacga gaaccaacgt gcgcaacgag ttacaaatgc agctctttat
    10981 ttgaaaaaac aaggtttttc tgagatttat atcctttctt atggcttgga ttcttggaaa
    11041 gggaaagtga agactagcta accttatttc caaattagtc gaatgatagg atgaagctat
    11101 tgttttatag tataattaat ttgtataaaa tttaaggagt tcttagaaca taaaagaaaa
    11161 gaagaaaaat ccactttttg tgggtatctt gtcgattatt cttggtttgt tatttccaat
    11221 tgtaggcctg attttgggta tcataggatt ggtcttggct atttcatacc aaaaagagtc
    11281 ataattagac tataaaatag aaaagattct taatatctta ggaattgtga tttctgtagt
    11341 taactggatt gtagcaatcg ccttaatttt tcggtaaata aaagaaaaaa gctttagttt
    11401 taaagctttt tttgttttat cgactcatct ctaaatagtt tttaatgatt tgtaactctt
    11461 tttggttcaa agggcggtag ttactttctg ctaaatctgg gttcaatgtg aagtccccaa
    11521 attggattct cttgaggata gtcaccttaa caccaaccga gaggaacatt ttcttgattt
    11581 gatgaaattt tccttctgaa atggtgatag aggcttgact gatggaggga cttgcagata
    11641 gaatctctag ttttgcgggt ttacagacag taccatctaa aaagacaatt cccttttgaa
    11701 aggcttggat atggtcaggt gttagaagtc cattaacctc aacttgataa gtcttatcga
    11761 catgatattg gggatggagg agttggaagc ccaagggacc gttatcggtc aagaggagga
    11821 gtcccgttgt atctcggtcc agtcggccaa cggcatagag cttgtcagac tggatgtcag
    11881 atggaagcag gtccatgacg gtcggaagtt ccttgtcttt gttggctgta acgacaccag
    11941 caggtttatg aagcataaga taggtgtgtt catagccttg aatgattcga tcctgaaaaa
    12001 ggagttcttg tagtcctgta tcgatatttt gagctaggga gcgggctggg caaccatcga
    12061 ctagaatttt ccctctgagg agtgcttgct tcatggcctt tcggctgatt ttttcttggg
    12121 ctaataaatt atctaaacgc atactgtgcc tatcttatca taagtcgctt gctttgaaaa
    12181 ggcttgacgt gaaaagaaaa gcggagtgaa aacatttaca cttgcttgag ttatgttatt
    12241 tatttgaaat tatggtataa tcgttcagtt agaaaataaa ttttgaatat tatagaggaa
    12301 atcatgacaa aattaagaga agatatccgt aacattgcga ttatcgccca cgttgaccac
    12361 ggtaaaacaa ccctggttga cgaattattg aaacaatcag aaacgcttga tgcacgtact
    12421 gaattggcag agcgtgctat ggactcaaac gatatcgaaa aagagcgtgg aatcaccatc
    12481 cttgctaaaa atactgccgt tgcttacaac ggaactcgta tcaacattat ggacacacca
    12541 ggacacgcgg acttcggtgg agaagttgag cgtatcatga aaatggttga cggtgttgtc
    12601 ttggtcgtag atgcctatga aggaaccatg ccacaaactc gtttcgtatt gaaaaaagcc
    12661 ttggaacaag accttgtccc aatcgtggtt gttaacaaaa tcgataagcc atcagctcgt
    12721 ccagcagaag tagtggatga agtcttggaa cttttcatcg agcttggtgc agatgacgac
    12781 cagcttgatt tcccagtggt ttatgcttca gcgatcaacg gaacttcttc attgtcagat
    12841 gatccagctg accaagaagc gactatggca ccaatctttg acacgattat cgaccatatc
    12901 ccagctccag tagataactc agatgagcct ttgcagttcc aagtgtcact tttggactac
    12961 aatgacttcg ttggacgtat cggtatcggt cgtgtcttcc gtggtacagt taaggttggg
    13021 gaccaagtta ccctttctaa acttgacggt acaactaaaa acttccgtgt tacaaaactc
    13081 ttcggtttct ttggtttgga acgtcgtgaa atccaagaag ccaaagcggg tgacttgatt
    13141 gccgtttcag gtatggaaga catctttgtc ggtgaaacca tcactccgac agatgcagta
    13201 gaagctcttc caatcctaca catcgatgag ccaactcttc aaatgacttt cttggtcaac
    13261 aactcaccat ttgctggtaa agaaggtaaa tgggtaactt ctcgtaaggt ggaagaacgc
    13321 ttgcaggcag aattgcaaac agacgtttcc cttcgtgttg acccaactga ttcaccagat
    13381 aaatggactg tttcaggacg tggagaattg cacttgtcaa tccttatcga aacaatgcgt
    13441 cgtgagggct atgaacttca agtatctcgt ccagaagtta tcgtaaaaga aatcgacggt
    13501 gttaaatgtg aaccatttga acgtgtacaa atcgacactc cagaagaata ccaagggtct
    13561 gttatccaaa gcctttctga acgtaaaggt gaaatgttgg atatgatttc aactggtaat
    13621 ggtcaaactc gtttggtctt ccttgttcca gcgcgtggtt tgattggata ctcaactgag
    13681 ttcttgtcaa tgactcgtgg ttacggtatc atgaaccata ccttcgacca atacttgcca
    13741 ttgattccag gggaaattgg tggacgtcac cgtggtgccc ttgtttctat cgatgctggt
    13801 aaggctacaa cttactcaat catgtctatc gaagaacgtg gtacgatctt tgtcaaccca
    13861 ggtactgagg tttatgaagg aatgatcatc ggtgaaaact ctcgtgaaaa tgacttgaca
    13921 gttaacatca cgaaggcaaa acaaatgacc aacgttcgtt cagctactaa ggaccaaaca
    13981 gctgttatca agacgcctcg tatcttgaca cttgaagagt ctcttgagtt cttgaacgac
    14041 gatgagtaca tggaagtaac gcctgagtct atccgtttgc gtaaacaaat ccttaacaaa
    14101 gcagagcgtg agaaagctaa caagaagaaa aaatcagctg aataagagct agaaagagag
    14161 aaagatggtc tatttagtcc taggaatttt actgctccta ctctatgtat ttgcgacacc
    14221 agaaagcatt aaagggacag tcaatatcgt cgctatggta tgtattttag tggcactctt
    14281 gattttattg gttctatctt ttctgaaaat ttttcaatta ccaacagaaa tattcctagc
    14341 aatagccatg ttgctcctag cttactttag tgttagagac attacactca tgccagtcaa
    14401 aaaaagtaaa agaagataaa aaagagagtt ttggctctct tttttgctag gaattttaca
    14461 agattgcaat ttatttttga gttatcacca tctcttttgt ttggataata tgaatgggaa
    14521 aaacttgaat aaaattcgtt aatggaatct attttatatt tggttagtac tggttgcata
    14581 ttattttgaa ataaaactac tatataatat tattcataga ggtaatatag taaaatatct
    14641 aaaaaattcg attttttcct tgacaacaaa taataaaaat gttattctta tcacataaga
    14701 aagcggtttc aataaaagag agaggaggat ttattttgtt gcattgttgc tcaaggtgtg
    14761 atttttttga aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc
    14821 ttatttcaag ttttacatta ttgggagctg catcagctgc tgtataatat ccagatggag
    14881 gagtatggac atatggagaa ggttcaggag gtggttaggc tttttcaaat tactatcatg
    14941 gtaaaaaata tcattattca tccatcgtga gcagatggga tggtcattct gataaaggag
    15001 aagctcctgc tggaaaaacc tcctatgcat ggatttggac taaatgggga gaacaagtag
    15061 cattttactg tgattatgac taatcgttca ttgatttaaa tcgttcccct tgtaagaaat
    15121 tacaggggga attttgttta caaggagtct accaaggagt ctactatgaa gaaactattc
    15181 atattattat caactttttt tctcagcttc ttccttgctt ggattattgt cttacgtgcg
    15241 ccacaatatt tatatgcaag ctatgattcc gtttctttac ttcgtgtcaa aaaagatact
    15301 caggaaccga cgcgtgaggt atttgaacag gaattggaga attttgcaaa ctcagaacag
    15361 agtttaatag ctagaagaat tgtagagccg agtaaggatg ggacgactca ctttacttat
    15421 gcaacttatg gtcagggaac tttaccaaaa gaattccaag aagctagcca agaaagtcgt
    15481 gaacgtagtg atccgctaaa tagttatctc cttttgtcag gctccttgac gaaagaaaag
    15541 cttgccgata aattaggaga tttgggttat aaagcaagtg ctgaccgaaa gataccgccc
    15601 tattttcttg cttttcgaat attactaaat ccccttattt taattagttt agcaatattt
    15661 ggcttatctt tctttgcttt agtgattatc actcggatta aggaaatgag agcagcaggt
    15721 ataaaactct tttctggtca gactctctta tccatcatgg ggcattcttt atctactgat
    15781 atcaaatagc tccttctatc agccctcctt tccttcctag gtgggggagt cgttcttttt
    15841 agtcaaggtt tgttttatcc tatcttgtta gccacctatg gttttgggat tagtttctat
    15901 ctgttgtttt tattggcgat ttcaatttta ctaatgcttc tttatctaat gagtttgagt
    15961 tacaaagcat tagttcccgt tattaagggg agattacccc ttaaacgcct gatgatttta
    16021 accctattgt gtcagttggt tgctgtcttt acagtaggat acgctgttaa gacaggtttg
    16081 acgtcttacc aacgattgaa agaacttgaa atttcaaaac aagcatggca ggatagagca
    16141 gactattatc aaatttcttt tggcttaggt gatagaggaa aagatacaga aaatcagagc
    16201 aagtggtatg cctttgccaa ggaagcaatc gaagaggaac aagctcttta tgtaaaggat
    16261 aatctgctcc attttgccaa tccacaagga aaaaatgaac agggagagac actggatacc
    16321 tatagtccag atgctaatac gctctatgtt agtcccagtt atttggacaa ggaaaaggtc
    16381 gtggtagatg ctgagaccaa acagaagtta gcccatctcc aaaaaggtga gtttatcctc
    16441 ttgctcccag aacatttgcg ctctcgagaa gcagaactta agaaagtttt tgaagaaaga
    16501 ttgagttatt atggaaaatc tggtgaggag gcaagtgctc ctttggatta tgagatgaaa
    16561 gcgcacgtta gttatctttc aatgggagaa aagcggtttg tttataataa cggtgagaat
    16621 cccgtatcta ctcagtattt gactgatccg attttagtgg tattcacgcc gacttctaca
    16681 ggtgatagtt ttatatcctt atctagttgg tctatcaatg ctggaaaaca actctttatc
    16741 aaaggatatg agagtgggct agaactcttg aagaaagctg gaatttatga gcaagtatcc
    16801 tatcttaaag aaggaagaag tgtttatcta actcgttata atgaagttca aactgaaaca
    16861 gcaactttaa tcttaggagc tattgtgggg atagctagtt ccttattact attttattct
    16921 gtcaatcttc tatatttcga gcaattccgc cgagatatct tgattaaacg aatttcaggt
    16981 ttacgatttt ttgaaacaca tgctcagtat atggttagcc aatttgccag ttttgtattt
    17041 ggtgctagtc tctttatttt aagcagtcga gacttggtga ttggcttgct cactttattg
    17101 gtctttctag ctagtgcagt tttgacgctt taccgtcaag cgcagaaaga atctcgtgtt
    17161 tctatgacaa ttatgaaagg aaaataggat gattgaacta aagaatatat ctaaaaaatt
    17221 tggaagccgt cagctatttt cagatacgaa tcttcatttt gaaggtggga aaatttatgc
    17281 cttaatcggt acaagtggct gtggtaagac aacactcttg aatatgattg gacgattgga
    17341 gccatatgac aaagggcaaa tcatctatga tggcacttct cttaaggaca tcaagccttc
    17401 tgttttcttt agagattact taggatactt atttcaagat tttggcttaa ttgaaagcca
    17461 aaccgtcaaa gagaatctca atctgggttt agttggtaaa aagttgaagg aaaaagagaa
    17521 aatctctttg atgaaacaag ctctaaactg tgtaaacctc tcttatttgg atttgaagca
    17581 acctatattt gagttatcag gaggagaagc acaacgtgtt gcactagcga agataatttt
    17641 aaaggatccg cctttgattc ttgcagatga accaaccgct tccttagacc ccaaaaattc
    17701 tgaggaatta ctttccatcc tagaatcttt aaaaaatccg aatcggacca ttattattgc
    17761 gacccacaat cctctgattt gggagcaagt ggatcaggtc attcgagtta ccgatttatc
    17821 acatagatga tatggtaaga ttcagttaga agaaagagtc acaaacacac tttgtggctt
    17881 ttttatttcc ataaaaatgg taaaatagta ggagtagaaa tggagttcga gacatgaaag
    17941 taatagatca atttaaaaat aagaaagttc ttgttttagg tttggccaag tctggtgaat
    18001 ctgcggctcg tttgttggac aagttaggtg ccattgtgac agtaaatgat gggaaaccat
    18061 tcgaggacaa tccagctgcc caatgtttgc tggaagaagg gatcaaggtc attacaggtg
    18121 gccatccttt ggaactcttg gatgaagagt ttgccctcat ggtaaaaaat ccaggtatcc
    18181 cctacagcaa tcccatgatt gaaaaggctt tggccaaggg aattccagtc ttgactgagg
    18241 tggaattggc ttatttgatt tcagaagcac cgattattgg tatcacagga tcgaacggta
    18301 agacaaccac aacgactatg attggggaag ttttgactgc tgctgggcaa catggtcttt
    18361 tatcagggaa tatcggctat cctgccagtc aggttgctca aatagcatca gataaggaca
    18421 cgcttgttat ggaactttct tctttccaac tcatgggtgt tcaagaattc catccagaga
    18481 ttgcggttat taccaacctc atgccaactc atatcgatta tcatggatta tttgaggaat
    18541 atgtagcagc caagtggaat atccagaaca agatgacagc agctgatttc cttgtcttga
    18601 actttaatca agacttggta aaagacttgg cttccaagac agaagccact gttgtaccat
    18661 tttcaacact tgaaaaggtt gatggagctt atctggaaga tggtcaactc tacttccgtg
    18721 gtgaagtagt catggcagcg aatgaaatcg gtgttccagg tagccacaat gtggaaaatg
    18781 cccttgcgac tattgctgta gccaagcttc gtgatgtgga caatcaaacc atcaaggaaa
    18841 ctctttcagc cttcggtggt gtcaaacacc gtctccagtt tgtggatgac atcaagggtg
    18901 ttaaattcta taacgacagt aaatcaacta atatcttggc tactcaaaaa gccttatcag
    18961 gatttgacaa cagcaaggtc gtcttgattg caggtggttt ggaccgtggc aatgagtttg
    19021 acgaattggt gccagacatt actggactca agaagatggt catcctgggt caatctgcag
    19081 aacgtgtcaa acgggcagca gacaaggctg gtgtcgctta tgtggaggcg acagatattg
    19141 cagatgcgac ccgcaaggcc tatgagcttg cgactcaagg agatgtggtt cttcttagtc
    19201 ctgccaatgc cagctgggat atgtatgcta actttgaagt acgtggcgac ctctttatcg
    19261 acacagtagc ggagttaaaa gaataaaata tgaaaaaaat tgtctttaca ggtgggggga
    19321 cggttggaca cgttaccctc aatcttttgt taatgcccaa gttcatcgaa gatggttggg
    19381 aagtccacta tatcggggac aagcgtggta tcgaacacca agaaatcctt aagtcaggtt
    19441 tggatgtcac tttccactcc attgcgactg ggaaattgcg tcgctatttc tcttggcaaa
    19501 atatgctgga cgtcttcaaa gttggctggg gaatcgtcca atcgctcttt atcatgttgc
    19561 gacttcgtcc acagaccctt ttttcaaagg ggggctttgt ctcagtaccg cctgttatcg
    19621 cagcgcgtgt gtcaggagtg cctgtcttta ttcacgaatc tgacctgtct atgggcttgg
    19681 ccaataaaat cgcctataaa tttgcgacta agatgtattc aacctttgag caagcttcga
    19741 gtttgtctaa ggttgagcat gtgggagcag tgaccaaggt ttcagatcaa aaaaatccag
    19801 aaccagatga attggtggat attcaaaccc actttaatca taaattgccg actgtattgt
    19861 ttgttggcgg ttctgcaggt gctcgtgtct ttaaccaatt ggtgacagac cataagaaag
    19921 aactaacaga gcgctacaat attatcaatc taactggaga ttctagcctg aatgagttga
    19981 gccaaaatct ttttcgtgtt gactatgtga ccgatctcta tcaacccttg ttggaattgg
    20041 ctgatattgt tgtgacacga ggtggtgcca atacgatttt tgagctcttg gcgatagcaa
    20101 aattgcatgt cattgtgccg cttggtcgtg aagctagtcg tggtgaccag attgaaaatg
    20161 cagcttactt tgtaaaaaaa ggctatgcag aagaccttca agaaagcgat ttgaccttgg
    20221 atagtttgga agagaagctt tctcacttac taagtcacaa ggaagattac caagctaaga
    20281 tgaaagcttc taaggaattg aaatctctag cagattttta tcaattgttg aaaaaagatt
    20341 tatcataagg aaagtaaatg tcaaaagata agaaaaatga ggacaaagaa atcctcgaag
    20401 aattgaaaga gttatcagaa tggcagaaac gaaaccaaga atatctaaaa aagaaggctg
    20461 aagaagaagc ggctctagct gaggagaagg aaaaggaaag acaagctcgg atgggagaag
    20521 aatctgagaa gtcagaggac aaacaggacc aggagagtga aacagaccag gaagattcag
    20581 aatcagctaa ggaagagtct gaagaaaaag tagcatcctc agaggatgac aaagagaaag
    20641 aagagaaaga agagaaagaa gaaccagagt ctaaagagaa ggaggaacag gataaaaagc
    20701 ttgctaaaaa ggctacaaag gaaaaaccag ccaaagcaaa gattcctggt atccatatct
    20761 tgcgagcctt cacgatttta tttccaagtc tgcttttatt gattgtctct gcctacttgc
    20821 tcagtcctta tgcgaccatg aaagatattc gtgttgaggg aacggtgcaa actacagctg
    20881 atgatattcg acaggcttca ggcattcagg attcggatta tacgattaac cttctgctag
    20941 acaaggcaaa atatgaaaag cagattaagt ctaactattg ggttgaatca gctcaacttg
    21001 tctatcaatt tccaactaag ttcactatta aggtcaagga atatgatatt gtggcctact
    21061 atatttctgg tgaaaatcat tatcctattc tttccagtgg tcagcttgag actagttctg
    21121 tgagcctgaa cagtttacca gaaacttatt tatcagttct ctttaatgat agtgaacaaa
    21181 tcaaggtttt tgtctcagaa cttgctcaaa ttagcccaga actcaaggcg gctatccaaa
    21241 aggtggaatt agccccaagc aaggtgacat ccgatttaat tcgattgact atgaatgatt
    21301 tggacgaagt cttggttccg ctttctgaaa tgagcaagaa actgccttat tatagtaaga
    21361 ttaagccaca attgtcagaa ccgagtgtga ttgacatgga agctggaatt tacagttaca
    21421 ctgtggcgga taaattaatt atggaagctg aggaaaaagc caaacaagag gctaaggaag
    21481 ctgagaaaaa acaagaagaa gaacagaaaa aacaagagga agagagcaat cgaaaccaaa
    21541 cgacccagcg ctcatcgcgt cgctaggttt accttttctc ttatagttct ttagtgacca
    21601 tgtttttact tgacaagtgc tagtagaaat aatagaatag taaaaaacct ttaaagcagt
    21661 ccagagaggc agctaaggtt agacggtgaa agggtggaga ctacccattt ttcgtggaac
    21721 cttgctgttg gcaggttcct tttttcgtgg cttctgttgg ccagactctc tcactagtaa
    21781 aggtaaaagg agaaacctat gcgagaacat cgtccagtca ttgctcttga ttttcctagt
    21841 tttgaggcgg tcaaggaatt tttagctctt ttcccagcag aagaaagcct ttatctcaag
    21901 gtagggatgg agctttatta cgcagcgggg cctgagattg tgtcctactt aaaaggtttg
    21961 ggtcatagtg tctttttgga tctcaaactt catgacattc ctaatacagt caagtcagcc
    22021 atgaaggtct tgtctcagct tggtgtcgat atgactaatg tccatgcggc tggtggtgta
    22081 gagatgatga aggcggcgcg tgaaggcctt gggagtcaag ctaaattgat cgctgtaacg
    22141 cagctgacat caacgtcaga agcccagatg caggagtttc aaaatatcca aaccagtctg
    22201 caagagtctg tgattcacta tgccaagaag acagctgaag ctggcttgga tggtgttgtt
    22261 tgctcggctc aggaagtaca agtcatcaag caggctacca atccagattt tatctgtctg
    22321 acaccaggga ttcgtccagc tggtgttgca gttggagatc aaaaacgagt catgacacct
    22381 gctgatgcct atcaaatcgg cagtgactat atcgtagtgg gacgtcccat tacccaagct
    22441 gaggatcctg ttgcagctta tcatgccatc aaggatgaat ggacacagga ctggaattaa
    22501 agaactagat tagaaaaata aaaggagaat accatgacac ttgctaaaga tatcgctagc
    22561 cacctcttga aaatccaagc cgtttacctc aaaccagagg aacccttcac ttgggcatct
    22621 ggtatcaagt caccgattta cactgataat cgtgtgacac tagcctatcc agaaactcgt
    22681 accctaattg aaaatggttt tgtggaagct atcaaagaag cctttcctga agtagaagtg
    22741 attgcaggaa ctgcaacagc agggattcca cacggagcca ttattgctga taagatggac
    22801 ttgccttttg cctacatccg tagcaaacca aaagaccacg gagctggtaa tcaaatcgaa
    22861 ggtcgcgtag ctcaaggtca aaaaatggta gtggttgaag accttatttc aacgggtggt
    22921 tcagttcttg aagctgtagc agcagccaag cgagaaggag cagatgtact tggagttgta
    22981 gcgattttca gctaccaatt gccaaaagca gataagaact ttgcagatgc tggtgttaaa
    23041 cttgtgacgc tttcaaacta tagcgagctt atccatctag cccaagaaga aggttacatc
    23101 acgccagagg gccttgatct tctaaaacgc tttaaagaag accaagaaaa ttggcaagaa
    23161 ggttaggtca gtaagataaa gagagacgag gctaccgagt ctcttttacc attttattta
    23221 aaatatgaca atattttaaa taaaataatt gacaacgctt tcttttattg atataatgaa
    23281 aatgtaatat gtatcaaatt gatcaatcaa ctatcttgtt tatcacttct taagaggacg
    23341 atgtcatgaa aagaagaaaa atatattcct tttttgcgta gttacaattg catctagttt
    23401 gtttctccct acagttttag ctagacagat tggagattat gatttaacgt tgccgcgttg
    23461 gggttcggat acaactagtg agcttgagaa agaaaacgcc tctgctggaa ttaataataa
    23521 tgacagcact ggtggcggta aaaggttaaa tacctctatt cgtagcgcct atagtgggtc
    23581 agatattacc ccggtatatt cattggggtc tggctctagg attgtcatgt actataatgg
    23641 aggtggtgac aattatattg gttctggtac tagattagct atggcgccac aatttggaaa
    23701 tcatgtaaga attcatactt caggttcttg gaatccagat tcttattaac ttacttgtca
    23761 gagtaagcct tagagatggt tgattgtggg tgtagcatga aaaaagaatg ctacacccta
    23821 tttttattat aaggaggagt aaggatggaa tttttcattt gtaatcttgt acgagtcgtt
    23881 caatcacctc gattttatat gtctttattt ttgacccttc tttgcatgag tttaggaaat
    23941 ttccttgctt tcaatggtat ttataaaatt gaaggtttat cgattttttt tgccgcttct
    24001 tctattcgag gattttcacc gattagccta gtagctgcac ttatctgtac actgccctat
    24061 tctagtcaga taatagagga tgctgagagt cattttctaa cagcacaatt gtgtcgaatt
    24121 tctaaaaaga agtatctggc tattgtgggt agtactgtaa ttatttcttc ttttctagtc
    24181 ttttttctcc cctatttatt attattagga attaatcttt tagtgactcc ttatcaggaa
    24241 atttatattg gagattatag tggtgcctta aaagaattat ttgattccaa tcagtttctc
    24301 tatagtcttg taacgactct ctggtatgga gtttggggcg ctgtgttctc tatttttgga
    24361 ctagctagtg ctttgctagt gaagaaaaaa ataggagcta ttttcatccc agttgcctat
    24421 atgatggttg gtggtatttt ttgggctatt ttagggctat cttacttaga acctgtgaca
    24481 acattagctt tgggatatca gaaagatatc agtctttcct tagttagtgg gcatcttgct
    24541 tttattttat ttgttagttg tttggttgtt tatggtacat tttttctaca ttcagaggac
    24601 tacgtataat gaaacaattt gttcaatttt acaaaaaa
//
LOCUS       DAVLTG010000026        24083 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLTG010000026 DAVLTG010000000
VERSION     DAVLTG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.026"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..577)
                     /locus_tag="VYN12_001169"
     CDS             complement(<1..577)
                     /locus_tag="VYN12_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1415564.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCISELTILQILYCASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSL"
     gene            complement(580..813)
                     /locus_tag="VYN12_001170"
     CDS             complement(580..813)
                     /locus_tag="VYN12_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1415565.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(826..1206)
                     /locus_tag="VYN12_001171"
     CDS             complement(826..1206)
                     /locus_tag="VYN12_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415566.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYSIEVTPHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELSIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(1199..1648)
                     /locus_tag="VYN12_001172"
     CDS             complement(1199..1648)
                     /locus_tag="VYN12_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415567.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLIPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(1632..2990)
                     /gene="dcm"
                     /locus_tag="VYN12_001173"
     CDS             complement(1632..2990)
                     /gene="dcm"
                     /locus_tag="VYN12_001173"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEV1415568.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKSTRLLFPFRREGQATNSEILKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKIAIPCITPDRLDKRQNGRRFKENQEAMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIKFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            complement(3089..3868)
                     /locus_tag="VYN12_001174"
     CDS             complement(3089..3868)
                     /locus_tag="VYN12_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1415569.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLNRGWIDEEGAVFLVFSNSKLMRLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     VKGRLANKIYLGELSSTPVDNSNRPSVNKRLGQVENETAPVSYSAPSETEVSETKYSE
                     TDSLFTEDEEDRNTHPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEALAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(3865..4038)
                     /locus_tag="VYN12_001175"
     CDS             complement(3865..4038)
                     /locus_tag="VYN12_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415570.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            complement(4247..5608)
                     /gene="rlmD"
                     /locus_tag="VYN12_001176"
     CDS             complement(4247..5608)
                     /gene="rlmD"
                     /locus_tag="VYN12_001176"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1415571.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLFRRFDLKPYDEKEHSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECVVLLQR
                     KKG"
     gene            complement(5682..6656)
                     /locus_tag="VYN12_001177"
     CDS             complement(5682..6656)
                     /locus_tag="VYN12_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1415572.1"
                     /translation="MRKKLFLTGAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(6730..7344)
                     /gene="pmp23"
                     /locus_tag="VYN12_001178"
     CDS             complement(6730..7344)
                     /gene="pmp23"
                     /locus_tag="VYN12_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1415573.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(7344..8318)
                     /locus_tag="VYN12_001179"
     CDS             complement(7344..8318)
                     /locus_tag="VYN12_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1415574.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(8326..9582)
                     /locus_tag="VYN12_001180"
     CDS             complement(8326..9582)
                     /locus_tag="VYN12_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1415575.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(9644..10075)
                     /locus_tag="VYN12_001181"
     CDS             complement(9644..10075)
                     /locus_tag="VYN12_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415576.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(10077..10679)
                     /locus_tag="VYN12_001182"
     CDS             complement(10077..10679)
                     /locus_tag="VYN12_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1415577.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(10663..11502)
                     /gene="prmC"
                     /locus_tag="VYN12_001183"
     CDS             complement(10663..11502)
                     /gene="prmC"
                     /locus_tag="VYN12_001183"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1415578.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(11502..12581)
                     /gene="prfA"
                     /locus_tag="VYN12_001184"
     CDS             complement(11502..12581)
                     /gene="prfA"
                     /locus_tag="VYN12_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1415579.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(12578..13168)
                     /locus_tag="VYN12_001185"
     CDS             complement(12578..13168)
                     /locus_tag="VYN12_001185"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1415580.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            13291..13473
                     /locus_tag="VYN12_001186"
     CDS             13291..13473
                     /locus_tag="VYN12_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1415581.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            13609..14982
                     /gene="mnmE"
                     /locus_tag="VYN12_001187"
     CDS             13609..14982
                     /gene="mnmE"
                     /locus_tag="VYN12_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1415582.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(15029..15964)
                     /gene="dapA"
                     /locus_tag="VYN12_001188"
     CDS             complement(15029..15964)
                     /gene="dapA"
                     /locus_tag="VYN12_001188"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1415583.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(16020..17096)
                     /locus_tag="VYN12_001189"
     CDS             complement(16020..17096)
                     /locus_tag="VYN12_001189"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1415584.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(17682..17754)
                     /locus_tag="VYN12_001190"
     tRNA            complement(17682..17754)
                     /locus_tag="VYN12_001190"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17719..17721),aa:Thr,seq:ggt)
     gene            complement(17854..18363)
                     /locus_tag="VYN12_001191"
     CDS             complement(17854..18363)
                     /locus_tag="VYN12_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1415585.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(18361..18457)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            18486..18917
                     /locus_tag="VYN12_001192"
     CDS             18486..18917
                     /locus_tag="VYN12_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1415586.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            18999..19376
                     /gene="mscL"
                     /locus_tag="VYN12_001193"
     CDS             18999..19376
                     /gene="mscL"
                     /locus_tag="VYN12_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1415587.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(19418..20512)
                     /gene="hemH"
                     /locus_tag="VYN12_001194"
     CDS             complement(19418..20512)
                     /gene="hemH"
                     /locus_tag="VYN12_001194"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1415588.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            20667..21890
                     /gene="pepT"
                     /locus_tag="VYN12_001195"
     CDS             20667..21890
                     /gene="pepT"
                     /locus_tag="VYN12_001195"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1415589.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASIQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(21926..22555)
                     /locus_tag="VYN12_001196"
     CDS             complement(21926..22555)
                     /locus_tag="VYN12_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415590.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            22520..22741
                     /locus_tag="VYN12_001197"
     CDS             22520..22741
                     /locus_tag="VYN12_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415591.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(22850..23326)
                     /locus_tag="VYN12_001198"
     CDS             complement(22850..23326)
                     /locus_tag="VYN12_001198"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1415592.1"
                     /translation="MTPNNGVSAADDGYVFNPNDIVRDTGDAYIVRHGDHYHYIPKSS
                     LNNPPSHSNTEEAGSSSSSVLSNPSLHVHHEEEDGHGFDANRIISEDSEGFVIPHGDH
                     NHYIKVQTKGYEAALKNKIPSLQSNYQPGTFDEKAVLAKVDQLLADSRSIYKDRLS"
     gene            complement(23366..23506)
                     /locus_tag="VYN12_001199"
     CDS             complement(23366..23506)
                     /locus_tag="VYN12_001199"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1415593.1"
                     /translation="MLEITLKSPYQFAHILFQPTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(23550..24083)
                     /locus_tag="VYN12_001200"
                     /pseudo
     CDS             complement(23550..24083)
                     /locus_tag="VYN12_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         7022 a         5097 c         4406 g         7558 t
ORIGIN      
        1 gcaaactata aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg
       61 atttatagcg taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa
      121 tggttcctgg atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta
      181 attttctaac caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat
      241 tgattaagaa caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg
      301 cttgatttgt gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc
      361 taacgaatcc aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt
      421 ttcgttgacc atacatccat aaaaaagaaa tgagcgacgc acaatagaga atctgtagta
      481 tggttaactc actaatacaa agcaatttca gtaagtatag ggataccaat aaaacattta
      541 cttgttggaa tatatacact ggaattattc ttttcatagt tacctccgaa ataaatcttc
      601 ataatctaaa tctaatacct gcacaatcct ttctacccat ggactttgag gcattcgttg
      661 ttccatcttg tagtggcgta tcttttgata caaacgattc aattcacttg gatagtgaaa
      721 ctctcccgca aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat
      781 aatggacaag ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata
      841 atgtgtttgt gccatgtaaa tcaattgttt cgtatctctt ggcaatagag ctctagcctc
      901 ttccaaattc agatttggat aaactctctt atttgaaact gcaagaggaa gtctgatgct
      961 tagttcagga ttttttaata tcatttcgat gaaatccgtt aatcttagat tgtcacgatt
     1021 cttaaatcgt aataaattgg gagataaaaa ctcaaaacaa tctgaagaat agctcatcat
     1081 ttcaattaat ttatcccttg tcatttcaga aatagaatga ggagtgacct ctatgctata
     1141 cttttgaaag aaatccaaaa gaagttgatt tctttggcta tttttactta gatagagatc
     1201 aatcatgaga gacctcccaa agattcggtt ccatttgata ttctgagaca atcaaggaat
     1261 ctaataaatt tgcgaagtta atcggtttct tgtcttcatc ataagctttt acagttactt
     1321 gggttgtaag tattccctct tttccctcgg ctcgatagcc ttgtccatat aaaacaaaaa
     1381 caagattttg attatcatct acaaaggcat caaccccatt ctttatgtct tgactttcaa
     1441 ggaattccat aacgttttga agataggact cgtaaaatag tgggtagttg tgttttttat
     1501 ggtaatcatc taaaaatgtt acttcaaact cacatggata attgggtatc aaaaataatt
     1561 gttcatccag ctgtttgatt tctgcatcat gtaattctgt ttctaattca tcacaatcta
     1621 gtattgattc tttatttaat gctttcatct ttttcctcta tttcttttaa tttctttgcg
     1681 attgcggcaa tcacaggaac ggttacacta ttaccagctt gtttatagag ctgactatta
     1741 ctagagactt ttctagcagc ttcaaaagcc caatcaggaa agccctgcaa gcgaaaacac
     1801 tctttaggag tgattcgtcg tatcctcaga cggtaaaact gtccatctat taatacaccg
     1861 gctacatgat aaacttgttt atcttctcct tcataactag caactactac tcccatttgt
     1921 ccactagttg ttaacgtatt agctatacct tttccaactc taccacgacg atactgagaa
     1981 cttggtcttt ccaaattaat tgaatctcct atttctgctt gagcgtatcc ttttttcgtt
     2041 gcttcccgta cttttagaaa tttgattggt tctggaatta gtattttggg aattttatct
     2101 ccaccttgca ttgtagtcag tgttggagat aacccctcac ttccataaac tcgaccagtt
     2161 tccttaaagc tagttggtaa atctccaaca acgacaatac catgacgatc ctgagtattt
     2221 aaagtaaaca tcgcctcttg gttttcctta aagcgtctac cattttgtct cttgtctaat
     2281 ctatctggtg taatgcaagg aatcgcaatc ttaaatcctt ctccttttcc acgaactaag
     2341 gttggcgcaa gaccttctga ataatagact ttaccgctca ttccactttt tgatggattc
     2401 aaattcccta atgtttttaa aatctcagag ttagttgctt gaccttctcg tctgaaagga
     2461 aataagagtc tggtactttt ctttctagaa tgtccgataa taaacaccct ctctctgttt
     2521 tggggaacgc cgaaatcctt actgttaagc acctgccact caacatcaaa ccccaactca
     2581 tcaagtgtgg taaggattgt ggtgaacgtc cgtcccttat cgtgattgag taggccttta
     2641 acattttcaa gaaaaagaaa acgtggttgg atttgtttgg ccgcccgagc aatttcaaag
     2701 aacaaagttc ctctagtatc ttcaaatccc aatcgtcttc ctgcgattga aaatgcttga
     2761 caagggaatc ccccacagat gatatcgact ttccctctaa gttttttaaa ttcgtcatct
     2821 gaaacatctc gtatgtcatg aaattcaatt tctccttccg tttgaaaaat ggacttataa
     2881 gattctctag caaatttatc aatctcacaa aatccaatac actcgtgtcc aacactttcc
     2941 attcctagtc gaaatccacc tatacctgaa aataaatcaa taaatctcat ttcttgatca
     3001 cccctttctg atcgacaatc aacgtccaaa gagttatacc acttgaaatt aaaatgagca
     3061 taactaatat ccactcgatt ggcgacattt aaccacctcc ttttctaaca cggttattcc
     3121 aaacagaata caagccgtta aacacaaatt cagcaagtgc ttccgctcgt ctaacaaagc
     3181 gaacattgtc aagagcatac tgatagattc tctcaaaatc agtcatagca atttcactgg
     3241 ctgtttcaga aaaaccttct cgtctaaatt gatcttgtac caatccccaa atataatctc
     3301 gatcatattt tgtgaccttt tctacttttc ttttcaagat aggatgagta ttcctatcct
     3361 cctcatcctc agtaaataaa gaatcagtct cactatattt agtctcacta acttcagtct
     3421 cactaggggc tgaatatgag acgggggccg tttcattttc aacctgccct agtcttttat
     3481 taacactagg cctgtttgaa ttatctactg gggtagaaga taattctcct aaataaatct
     3541 tattagctag tcttccttta acacttgaag actgttgaac ttcatcaatt aagtcatatt
     3601 ctttaagagt ttttttgatg gacagtaatt ttgacttcga acaacctaac agcctcatca
     3661 gtttagaatt agaaaatact aaaaaaaccg cgccttcttc atctatccaa ccacgattga
     3721 gagataattc taaacgatct tttaaaatag aataagccac ctttacttct agtttcatat
     3781 ccatatattt ctcatcctca aaaagaattt taggtaattt ataataccgt tctgaagttt
     3841 ggtattgatt tgcggtaatt cgtttcatag cgctcctcca agttctttga gtattaaatc
     3901 tccacttgat tccaatcgaa ccaagccact tttttctaat tcagccataa gagagatggc
     3961 ttcaacaata tctattccca tttcacgtac taaaaatgaa atgacaatat agcgtgatga
     4021 ttgtaattct tttgtcattt tccctcctga aaataaaaaa aggagaacaa aatacaattg
     4081 ttctctcttt agataaatat ttattgttgt attcattttt ccaatgcgca aacgacatct
     4141 acaaatacat atacatctat gtgccttttt aggacttttt tgacgtcaaa attgccttta
     4201 tctacaaaca caaaatgctt gtaaaatagc ttaaaatcaa ggattttcac cctttttttc
     4261 gttgtagcaa cactacacac tccacgtgat gcgtttgagg aaatagatcc accggctgga
     4321 ctttcttcaa ttcatatccc aactcttggt atagtttaat atcacgcgcc atggttgcga
     4381 cattgcagga gatataggcg atgcgatcgg ctcctgtttg ggcgcttgct ttgataaagc
     4441 tttctgtcaa gcccttgcgt ggaggatcaa ccaagataac ggttggttga atcccatctt
     4501 taagccaatt cttcatagca ttttcagctg tgtcacagac atagtgggcg tttgaaatat
     4561 tgttcagctg agcatttttt ttactattct caaccgcttc tggaatcagt tcaacaccgt
     4621 agacttcttt gacatgcttg gcgactgata aaccaatggt tccaatacca gaataagcat
     4681 caataaccac gtcatctttt tttaactctg caaagtcaat ggctgtttga tagagtttct
     4741 ccgccatttc agtattgact tggtaaaagg ctgggccagc gatttggaag tcatttccca
     4801 acatctggtc cgtaatatag tcttgaccat aaagagtgcg ccactcctta ccaaaaatcg
     4861 cattggtatt ctggtcgttg atattttgca tgacagacac aatctctggg aactgcttga
     4921 taacttgttc aatcaattgg tcaacacgaa aaacttttgg acgagttgtc accaaaacga
     4981 ccatgatttg ccctgaatag tgaccacgac gcaccacaag attccgaatc aatccagaat
     5041 gttccttttc gtcataaggt tttaaatcaa aacgacggaa caggtctcga agagctacta
     5101 cgacttggtc aatgacagga tcctggataa agaaatcttc aaggggcatg aggttgtgcg
     5161 aattcttacg gaaaaatcct gtttccaaga caccattcac tcgacgaacg ggcacctgcg
     5221 ccttattgcg atacttgact ggatgttcca taccaagcgt ttcagcaact tctacatctg
     5281 caattccagc aatcttgtag agactgtcct tgacttgctt ggttttaaac ttgagctgtt
     5341 ctggataaga aaggtgtcct aaatccgcga ttcctgaacg caggtaagcc aaatctagat
     5401 cttgattacg gtgtggtgac tggacaaggt atttttcaac ttttccaaag ccaatctttt
     5461 tattgacctt gaggacacgc atgagaattt tttcactcgg taaagcattc tctacaaaaa
     5521 agaccaaacc atctaccttg gcaactcctg ccccttcatg ggtcaaatca acaatttcaa
     5581 cttctacaat atcatttttc tttaacattc ttttctcttt ctattggccg acaaaaaaga
     5641 cggcaacgtt acggttacca tccattatac catgaaattt cttaagaacc aaaactcttg
     5701 aagaagttga caagggcttg ccagagggag cttaagaagt taccaccgtc ctctagcgcc
     5761 ttatccgcat caaagttaag gttgatattt ttaaaactgt cgccagcttg tgatacgatg
     5821 ctttgtttaa ggtcatttag ggttttagtg aaatctgcat tgctgaggat atcactcttt
     5881 gagagattca aggcaaaatt gatgatgata ttgatctggt ttcctgttat gacctgatca
     5941 agtttgtaat tttttaaggt atcttcaaca atcttgcgta catcttcttc tgtcagattt
     6001 cccttgcttt ctttagcttt ggcgagtcct gacttgatat cagctagggc aacgtttaat
     6061 ttattagcat catagcctga tttgtccttg ttttcagcat tgatatctga caaagccttt
     6121 agctcttctt gagccaaatc tttattggct tgcggcacct tggctccatt agcttctagc
     6181 gaatagtaga tcccagccaa agcactctca cctgtaactg gaataggggc tgctacagtg
     6241 attttggcat gttccatacc cagcgttact gctgcgtttc ggtacatatc ctgagtcacc
     6301 ttagtgatat tttctggtgt ttcaatcttg acctcaagtg gcgatttgtc acctagcttt
     6361 tgaatcttgg ctgatgaata caactgtaag ctagagtcat tggccacatt catgatttta
     6421 gaataaacat caggtgtcat ggtcttgagt tctttggtat ctgttgaggc attgtagccc
     6481 agttttttaa gagtttgatt tttttggtct tcagataggg aggaacctag gacatattca
     6541 ggttggacat aggtttcatc gataactttt tgaacatctg ttgctgcatg ggcgctattc
     6601 atagctgtta ctgcccacaa gaccgcagca ccggtcagaa agagtttctt tctcataggg
     6661 aatttcctcc tttacttttc tagagtaata tatctatctt aaagaaaact tataacaaaa
     6721 acacctggtc tagccagatg ttgaaaagag agtgaaacat ttgatgatgt aaaggttaag
     6781 tcgtacctgt ctagaataat aatagtttcc tccatttaca tagagttcag caccgtgaaa
     6841 aatggaaatg gggtgaatat aactataagt ctttccagtc ctattaccaa gcaagggggc
     6901 aacagtctca cgagagtact gtttggctag agccaaggta ttttccttgc cattttgggc
     6961 gataaaatcg atataggcag gtccaaaatt ataggcttga acagctgtcc agatatctac
     7021 acccttcttc tgcgccagat agagattgcc tgtcagagtt tgaatgcctt gccgaatgct
     7081 agaggcatta tcattgatgg tgttggtgga accacttgca gactcactag actgcataac
     7141 atcgccttct tttccttttg tttcagtata aatcatagca agcacaagct cttcgtttgc
     7201 tggggtgtct ttttcactca atatttctcg caccatgggt tgataggtca tgacttgttt
     7261 gacatcttga tgaacgcggt aagctttata gccagcaaaa aggaagactg ctagtacaag
     7321 cactcttcga attcgtttaa acattattta ctttggatat cctcgatatt tttgattaag
     7381 atagagtagg ttccattttc gttttggata aactcaacag actcggcgtc ttgatagacg
     7441 ttattgggaa cgatgagctc aattccattt gataaggaga gtttttggtt ttcaaatttc
     7501 tttaattggc gactggcatc aatttcatca aattgaacag gttctggtac ggcttctttg
     7561 acttggtcaa taaagctcaa acgagccgtc agattgttgt caaaaaggtc attagccaat
     7621 ttctcaggtg acaattcatt gctttcttct aggttgttga aaatagctga tttgaccttg
     7681 gattgaaatt gaaaatcatc tgtgttaaaa gattcagcaa ttctctgggc tgttttttcc
     7741 agttccttga tagatttttt aggagaaatc ttaggagcga cagcaagaag attatctgaa
     7801 aaatagttca aaaaagtccc gttgtacttg attcgttttt caatcaggtg atacttgcga
     7861 ctctgaagat tgaccaccaa ggcctcgtca gcacccgttc caaatccagg caggttattc
     7921 tgagtcagct tgattggatt atcaacttct cctccgaggt gggtcaaggt ctcccgcagg
     7981 gcaattcgca agaaagcgaa atgttctaca ccttctttag aaaattgaac aaaaatcaag
     8041 tcattggtct tgagattttc agaaatgcta aactcctctt tccagagatt agccagcgtt
     8101 actgatgtct ccaacaaatc gtctgtaata tgattgaaga agggattttc ttcttcgaaa
     8161 atcccagtct tggcttcatc tgaatacaca tgttcaattt ttttacgtag gtattcttcg
     8221 atttttggag taatattgag aaacttatct gctaagaaca gctcggtatc atccggactg
     8281 aactggtgaa taatggcttt cttaatataa atatccataa aagttttagt cctcgtataa
     8341 tgggaaggca tctgtcaatt ctttgactgc acttctcact tcttctaata cagcctcatt
     8401 ttctgaattc ttaagggttt taatgatgag ttcagccact ttgcgacttt cttcttcacc
     8461 aaatccacgt gcagtaatag ctgctgctcc gatacgaatc ccacttgtct tgaatggcga
     8521 caaggtttcg taagggattg aatttttatt tagggtaata ttgacttcat ccagcaagtt
     8581 ttgagcaact tttccgtttt ctacaacctt agtcacatca acaaggaaga gatggttttc
     8641 agttccacct gaaataatac ggaaatcagg gtcttgcaag aagacatctg ccatagcctt
     8701 gctgttctta attacattgg cagcatattc cttgaaggct ggatccaaaa cttctttgaa
     8761 ggaaactgcc ttagccgcca caacatgctc taaaggaccg ccctgaatac ctgggaaaat
     8821 agctgaattg atttttttag caagttcttc gtcattggtc aaaatcaaac caccacgagg
     8881 tccacgaagg gttttgtggg tcgttgttgt tgtgatatga gcgtatggaa ctgggcttgg
     8941 atgaaggcca gccgcaacca aaccagcgat atgggccatg tccaccatga gcttcgcacc
     9001 gacagcatct gcgatttcac ggaattttga aaaatcgata atttgagaat atgctgaagc
     9061 accagctaca atcagttttg gttttacttc ttgggcttgt ttcaagatag catcaaagtc
     9121 taagagttcc gtttcaggat caacactata agaaacaaag ttgtaggttt gaccagagaa
     9181 gctaacagga gccccatgag tcaagtgtcc acctgctgcc aaatccattc ccataaccgt
     9241 atcacctggc tcaatcaagg acatgtaagc cgcacagtta gcttggcttc ctgaatgtgg
     9301 ttggacattg gcaaatttag caccgaaaat ttcttttgcg cgttcaatag caagagtctc
     9361 tacaacgtct actacatcag ttccaccata ataacggcgt cctgggtaac cctcggcata
     9421 tttatttgtc aagatagacc cttgagctgc cataacagcc ttggaaacta cgttttccga
     9481 agcaattaac tcgatattat tttgttggcg ttcttcttct ttggcaatag cattccagag
     9541 atcagcatca tatgctttaa aatcatcttt gtcaaaaatc ataggtcttc tcctttattg
     9601 tgtgactagt ccattagttt gattttacaa taagaaaatc aaactaaaag atgcgaataa
     9661 accgtttctg cattttatca caagtatagc caactttttc ataaaatgca tgagcaccca
     9721 gacgatgatt ggcagaattt aagcggataa acccataacc acatcttttt gcttcttctt
     9781 ccaacccttg tagtaaactt ttaccaatac cttgaccttg cgcttgaggt gaaactgcta
     9841 aagctaagat attaaatcct gctttggaat agagtgattc gtaaacttca gcgtggacat
     9901 atccaagtaa gacatgatta gctgcatcct catagccaag taggaaatga tgggaatcct
     9961 gagacagtct agctagttgg ctagccgttt cctctggact aaaagtataa cccaaagcct
    10021 cttggttgat gtcacatatc gctttcacat ctgtttcttg caaatctctt agcatttcaa
    10081 gcctcctcaa aagaaatctc tggcaaccga gcaagaatat cttctcgttt aattgcgcct
    10141 tggcgtaaga ttttcacctt gtctccagac aaatccacaa tagttgaatc ctgtccagtt
    10201 agaaaagcat cgtcttccag acccagaacc tcttggtcaa aatccttcag aatttgttca
    10261 aaggttacac cacttgcctg acctgagata ttggcagacg gcccaatcaa gggacctgtc
    10321 tctcgaatta aatccagtgt gatagggtga ctgggcatcc gaaatccaat agttgcaagg
    10381 tcagaattta cccaataggg aactcggtca ttggcttcga gaataatggt caagggacct
    10441 ggcaaaaagg tctctacaag tttttgtaga taagttggct gattcttaga aaagtgcaag
    10501 atatcctcga aagaggcgat attgagattg agtgccttat ctctaggacg acgtttgagt
    10561 tggtaaacat ggtcaactgc tttttcatct aaggccttgg caaaaagacc ataaacagtc
    10621 tctgtaggta gaacgacagc tccaccattt tccaactctt gtctaatcct gtccatcatc
    10681 aaccacaacc atcctatttt gaccaaattg gtctttgagt gttcgaactt ttttttcagg
    10741 aagatgtttt ctaaaaagtt cgggaacact ttgaccttgc ttgtatccaa tttcaaggta
    10801 aatcttacca ccatccttga gatagtcttt tgcatcttcc gcaattctac agtaaatagc
    10861 taggccatcc tcgtctgcaa agagagctag atgaggctcc gaatgcaaaa cattcaaacc
    10921 tacctctgac tcatcttcac gagagatata gggtggattg gatacaatta tatcatattt
    10981 ttcagaaatt tctgcaaaac aatcagattt tttaaaaaat atattaagat tttgatcgct
    11041 agcattctct gatgcaagct ctaaggcctc ttgagaaaca tctgctgctg tcactgacca
    11101 atctggtcta ttttttgcta gagcgagagc aatagctcca ctacctgttc caatatccag
    11161 aactgagaga ttcgtctcaa gattttcagt tagaataagc tccactaact cctctgtttc
    11221 tggacgagga atcaaaaccc gttcatccac ctttaaatgc attccataaa aatctgcctg
    11281 tccaatgatg tactgagctg gcttgtgagc tgctagttgc tggtaaatat cttctacaaa
    11341 ttgtttttct tcctctgttg tcacctcctg ctggagggca aaaataaagt ctgtaaaaga
    11401 tagatttttc agactacgat agacaaaaga gaggctttcc gcttcctctc cttgtcttat
    11461 caactcttct tcaaaatttg aaaataattg agctaatttc attatttgtt taattcttct
    11521 agtttttgtg tttggtcata aagcaccaag gcatccacaa cttcgtccaa tttaccagac
    11581 aaaatcgtat ctagtttttg gagggtcaag ccgatacggt ggtctgtgac acggttttgt
    11641 gggaagttat aagttcggat ccgttctgaa cggtcaccag taccgattgt cgacttacgc
    11701 tcagcgtctt gttcatcctg agcaatctga gcaaagtggt cagcgacgcg tgcacggata
    11761 atcttcatag ccttctcgcg gttcttctgc tgggtacgtt cttcctgcat ctcaaccttg
    11821 atattggttg gcaagtgaac gatacgaacg gcagtcgcaa ccttattgac gttctgtcca
    11881 ccagcaccag aggcgtgata gatgtcgaca cgaaggtctt ttggatcaat gtcgtattca
    11941 acctcttcaa cttctggcat aacaagaact gtcgctgtcg aagtatgaac acggccttgg
    12001 ctttctgtca caggaacacg ttgcacacgg tgggcacctg attcatactt aagcttagag
    12061 tatacagact gacctgaaac catagcaacc acttctttaa aaccaccgac accattcata
    12121 gaggcttcca tgacttcaaa gcgccaacct tgggcttccg catacttttg gtacatagtt
    12181 agcaaatctc cagcgaaaag tgccgcttcg tctccaccag ctgctccacg gatttcaagg
    12241 atgatattct tgtcatcgtt tggatccttt ggaaggagca aaattttcag tttttcttca
    12301 tattcttctt tttcagcctt ggcatctttg agttcttgct tggccatttc ttccaagtcc
    12361 gcatctccgc ctgattcctt aatcatctct tcggcatcga cgatattttg aaggacttgt
    12421 ttatactcac ggtaggctat tacggtgtca cgattggaag cttcttcttt tgaaagctcc
    12481 ataaaacgct tggtgtctga aacgacatca gggtcactca gcaattctcc tagttcttca
    12541 taacggtctt ctacagcttg tagttgatca tagatgttca tttttcttca ttctccttat
    12601 tgatttcagg ggcaaaataa tgtttacggc aaaccgagat ataggtttca ttaccaccaa
    12661 tctggatctg ttctccatcg taaacgggca gtccatcctg tgttcgcaac accatggtcg
    12721 cctttttctt gcaatactga cagatggtct tgatttcgtc aatcttgtct gctaaaagca
    12781 agagatattt ggaaccttcg aacaattcat tgcgaaagtc atttttcaag ccaaaagcca
    12841 tgacgggtat gtctaactcg tccacaacac gagctaggtc ataaacatgg tggcgtttga
    12901 gaaactgggc ttcatcgacc aaaacacagt aaggtttttc tggtaggtct cggatatagc
    12961 caaagatatc cgttgtttcc tcaatcgcaa gggcagggcg tttcatgcca attcgactcg
    13021 acacatagcc aacaccgtca cgcgtatcca gagccgaggt cataatcaca acaccttttc
    13081 cttgctcctc gtagttatag gccactttga gaatctcaat cgttttacca gagttcatgg
    13141 tcccataacg atagtacaac tgtgccatgt ttcttgcttc acgtccattt ctaaattttt
    13201 gctacattct agtatatcat aattttctta agctttaaac ggcaaaatgt ggtaaaatgg
    13261 aagaaatcaa aactagtgga ggaagctatt atgccatttg tacgcatcga tttatttgaa
    13321 ggacgcacgc tcgagcaaaa gaaagctctt gctaaggaag taacggaagc ggttgttcgc
    13381 aacactggag cacctcaatc tgctgttcat gtcatcatca acgacatgcc agaaggaact
    13441 tatttcccac aaggggaaat gcgcaccaaa taagctagct taagcagaat tgcttaggct
    13501 ttttcaatct ccaagtagca cccattgaag aaatagtcta aatttgttac aatttgaaaa
    13561 gagacttgga aaattccaag aaaagagcaa ttaattaaag gaaacattat gattacacgt
    13621 gaatttgata ccatcgctgc tatctctact ccactaggtg aaggggctat tggtattgtc
    13681 cgcctgagcg gaacagacag ttttgctatt gtgcaaaaga tttttaaagg aaaagacttg
    13741 aacaaggttg ccagccacac tctcaactac ggtcacatta ttgatcctct gactggtaaa
    13801 gtcatggacg aggttatggt tggggctatg aagtctccaa agaccttcac tcgtgaggat
    13861 attatcgaga ttaacaccca cggtgggatt gcggtgacca atgaaattct ccagctagct
    13921 attcgtgaag gggctcggtt ggcagaacct ggtgaattta ccaaacgtgc ttttttaaac
    13981 ggtcgcgtag acttgacaca ggcagaggct gtgatggata tcatccgtgc caagactgac
    14041 aaggccatga acattgcggt caaacaatta gacggctccc tttctgacct cattaacaat
    14101 acccgtcaag aaatcctcaa tacacttgcc caagttgagg tcaatatcga ctatcctgaa
    14161 tatgatgatg ttgaggaagc tactactgcc gttgtccgtg agaagactat ggagtttgag
    14221 caattgctaa ccaatcttct tagaacagcc cgtcgcggca aaatccttcg tgaaggaatt
    14281 tcaacagcta tcatcggacg tcccaacgtt gggaaatcca gccttctcaa caacctcttg
    14341 cgtgaggaca aggctatcgt aacagatatc gctgggacaa cacgagatgt catcgaagag
    14401 tacgtcaaca tcaatggtgt acctctcaaa ttgattgata cagccggtat tcgtgaaaca
    14461 gatgacatag tggaacaaat cggtgttgag cgttcgaaaa aagccctcaa ggaagccgac
    14521 ttggttctac tagtgctaaa tgccagtgaa caactgactg cgcaagacag acaacttctt
    14581 gaaattagcc aagataccaa tcgcattatt ctacttaata aaaccgacct gccagaaacg
    14641 attgaaactt cgaaactacc tgaagacgtt atccgtattt cagtccttaa aaaccaaaac
    14701 atcgacaaga ttgaagagcg aatcaacaac ctcttctttg aaaatgctgg cttggtcgag
    14761 caagatgcta cttacttgtc aaacgcccgt cacatttccc tgattgaaaa agcagttgaa
    14821 agcctacaag ccgttaatca aggtcttgag ctggggatgc cagttgattt gcttcaagtt
    14881 gacttgactc gtacttggga aatcctcgga gaaatcactg gggatgctgc tccagatgaa
    14941 ctcatcaccc aactctttag ccaattctgt ttaggaaaat aagaaaaatc catgatcctt
    15001 cattcggtca tggattttat tgtctttatt agtaatctgg tcttaagacc cctgttacag
    15061 ttgccttagt tgcttcgtag tcgccatcta cgacaacctt gataatgcgt ttggcatctt
    15121 cttctggtgc tggaacaaga ggtagacgag tgggtccagc ttcaaatccc atatagttaa
    15181 gaattgcctt aactggagca ggacttggat aagagaagag agcattaacc ttaggaatga
    15241 atttacgctg aattgctgcg gctttcttca tatcgctttc tgcaatggca gtaaacatct
    15301 cgtgcatttc atccccattt gtatgagagg caacagaaat aaccccatcc gccccaaggt
    15361 tcatggcatg gaaagcatct ccatcctcac ctgtataaat caagaactct tcaggcttgt
    15421 gctcaatcaa gtaagccata ttagccaagc tagtacattc tttgacaccg ataatatttg
    15481 gatggtcagc caagcgaagc atggtttctg gagtcaattc gaccactaca cgccctggaa
    15541 tgttatagat aataattggt aggtcagaag catctgcaat agccttaaag tgctgataca
    15601 tcccttcttg agaaggtttg ttgtagtaag gaacaatagc aagcccagct gcgaaaccac
    15661 caaattccgc tacttctttg acaaactcaa tagagtcacg cgtatcatta gtacctacac
    15721 ccgcaatcaa aggaacgcgt ccattgacaa ccttttgtac agccgcaaac aactccaact
    15781 cctcatcgtg ggtcaaagtt ggactctcag cagtcgttcc tgcgagaaga attccatccg
    15841 tatgatgggc caataaatgc tcaatcaagg ctggaatagc atcaaagtta atggaaccat
    15901 cctcatggaa gggggtaata aaggctgtaa tgattttaca ttcttttaaa tcttgataag
    15961 acacgaaaac acctctctat ttcaaagaag gagttcatct gaactcctaa acgatatgac
    16021 tattttaatt caaatttcaa ttcagctgtt ggacgaacca atccacgttc atgaagagtt
    16081 tcagcaatct gaactgagtt ccaagcagca cctttgagaa ggttatctga aacaacccac
    16141 atgtgaattc ctttttctgc atccaagtct ttacggatac gaccaacaaa ggtatcacgt
    16201 gaaccaactg cattgatggc ttgaggatag atttgatgaa ctacatcatc ttcaagaaca
    16261 gcacctggga aggatgcgat agctgctttg acttcttcaa ttggagccac ttcctttgtt
    16321 tcaatataaa ctgactcaga gtgagctgac aagactggaa tacgcacaca tgtcgcagat
    16381 actgcaatgc tatcatcttc cataattttc ttagtttcct tggtcatctt catctcttcg
    16441 tacgtgtaat cattatcagt gaagacatca atttgtggaa gagcgttaaa ggcgatagga
    16501 taatgtttct tgtcaccacc tgaaggcaag atttccgcat gcaaatcacg tggtttcact
    16561 ccatcattca agacctcacg aagttcacgt tgtgtctcaa gaattgctcc cataccagca
    16621 cctgaaacgg cttgataagt tgaaacaatg atacggtcca agccccattt ttggcgaacc
    16681 ggctcaagag ccaccatcat ttggattgtt gaacagttag ggcaggcaat gattccgttg
    16741 tgggcatcaa gtgcatgagc attgacctct ggaacaacca aaggaacatc tggattttga
    16801 cggaaataag atgtattatc cactactacc acgccagctt ttactgcgta tggtgcatac
    16861 ttagctgatg tcgaaccacc tgctgaaaag agagcaatat caactccttc aaaagctgtt
    16921 tcagtcgttt cttcaatcgt aatatcttga tctttaaatt tcaatgactt acctgctgaa
    16981 cgtgcagaag caaggtaacg gattttatcg attggaagtg ttgattcttc caacattttt
    17041 atcatctgag caccgacagc acctgtcgcg ccgactacag caactgtata tcccataaat
    17101 aacctctttc ggaattttct aaaaatttct ataatagaag tattatacta ctttttccat
    17161 gaattgcaaa gctttttcat cattttttgg aaaataaaaa tccccaatcg ctagactagg
    17221 gattaagagg catcttcatg tgatgagcag gttcacacaa ctcatcaagg tccgctcctg
    17281 cgttatgacc tccttatgct caatagtagc ccgaagacta cctatcgact catcgcatct
    17341 actattctac taaagagaat gacttttgtc aacagacgaa actctttata ctcttcgaaa
    17401 atctcttcaa acttcgtcag cgtcgccttg ccgtatgtat ggttactgac ttcgtcagtt
    17461 tcatctacaa cctcaaaaac atgttttaag ctgacttcgt cagttctatc tacaacctca
    17521 aagcagtgct ttgagcaacc tgcggctagt ttcctagttt actctttgat tttcattgag
    17581 tattagtttt atttacacag gtgcataaga aatatattgg aaaaattggg ggcagacata
    17641 acaaaaaccc ttgtaaatca agggcttttc tgtctattta atgctaattg ccgggattga
    17701 accggcgacc tcatccttac catggatgcg ctctgccaac tgagctaaat cagcttactt
    17761 aagaagtata ctatattcag aaaaacttgt caagtttcct tagaaatttt ccataggaaa
    17821 aagccaggta agaactacct agcttatctt cttctattta cttaaatcaa ttcgacgacc
    17881 aattttacca ataataatcg ctccaataat caatgaagca aattcaccga ttcctgttgt
    17941 aaaccaagta aggaagaatg gtaattctgc tacaatattt aactctgcag cgatagtaaa
    18001 catggaaatt gaaaagagga ttgaaaagaa gaaatgatct tttcgaatca atccgttaaa
    18061 gaggtaatcc ttgctatatt ttgcaaaaag ccaaacacct aaactgagga atactaaggt
    18121 tgaaccacca ccaacaaaga catctagcag tccgaagcta aagaaattag caatcataca
    18181 accgatggta actccgatga tgtacttagg attgtaaaaa gccataaagt tcatcatttc
    18241 tgaaatacga aactgataag caccatagct gatggcattt aggggcggtg tgacagtcaa
    18301 aacgacgtag atagcagcga cgattgcaat atctgcaaca tcacgaatag ttaatttttt
    18361 catcttttct cctttggcgg ttatccgcgt gtaatatgct tggtgaaaga agctaagcac
    18421 caagggttga ttcattcaac cttactagta tagcacaata gcctgcttta tgctatactt
    18481 aaagcatgaa aaaacctatt caaaaatttt ttaacaatga aatcttagcc tatctctttt
    18541 ttggccttgc gacaactcta gtttcgattc tctcacgact agtcatttat caactaagtc
    18601 atcaggaact ccttgctacg gccttggcaa atattatcgg tatcttattt gcctttatca
    18661 caaatgatac gattgtattt aagcaaaaaa agaaaaatag acttatccgt ttagtgaaat
    18721 tttctcttgc tcgcctttct acttttctgt tagacttgtt tttaactttt ctctttgtaa
    18781 cccaatttcc tcacatcata gggcaattcg taactgaaaa cattgataag ataaatgcta
    18841 ttgaaacaat aattgcacaa atattcatta ttatcatcaa ttatatcttg agcaaggtct
    18901 atatttttag aaaataatgc tccatttatg agccttttaa ttgccttcta taatgattta
    18961 ggatacaatg aaacacgaaa cattgaaagg aaaacagtat gttaaaaaat ctaaaatcgt
    19021 tcttgcttcg aggaaatgtt attgaccttg ctgtcggtgt tgtcattgcc tctgcttttg
    19081 gtgctatcgt tacttcactt gtaaacgaca ttatcactcc tcttatttta aatcccgctt
    19141 tgaaagctgc taaagtcgaa cgtatcgctc aactttcttg gcatggagtc ggctatggta
    19201 actttttaag tgctattatc aattttatct ttgtgggtac cgccctcttc tttattatca
    19261 agggcattga aaaagcacag aaactgactg gcataaagaa agaaaaaact gccgaaaaaa
    19321 aaccaaccga attggaagtc cttcaagaaa taaaagctct ccttgagaaa aaataatcga
    19381 ttaaaaggat ctagcgcaaa gctaaatcct tttttcttta ctctttgggt aacttgcctg
    19441 ctttttcaag catttttttg ataagataag gcatcttaac attctcccgc ccttttttct
    19501 caatcagttt tttcacaaat tctggcattt gtaaatcttc agattcagct aaaatgtttt
    19561 tcgtctcgtc tgaaggaact aactcatcaa aggtctcttc ttctgggaga aattccttaa
    19621 actcttgatt ttcattgact ctaactgtat tgaccaaagc atcaatcaaa cgagaatctg
    19681 tatttggcat tggtggacga tggtagttta ccccaaattc ctggcataag tcataacatt
    19741 ctacatcatt gtcaaacaag acctcaatat gctcactgat gaaactaata ggtacaaaaa
    19801 tataatggtc tggatgttct gtctgttctc tgagatactc caaaacatct ggtttaatcc
    19861 atggaatacc aatatcactc tcactctgcc aagtgttggt atattgttct gaactcaagc
    19921 ccagtttttc agcgactagc ttgctatttt cgaaaatttg gtctatataa ggatcaccaa
    19981 agtccaaggc aaaaatgggc acactatggg ctgaaaagat gactttaaag ctgtcttgct
    20041 ttacttcttc ttttaaaatc ttagcaattt catctgccca atagtttaag agcgcttctt
    20101 cctgatacca gtccttaatg accaaaaatt gaatttgttt gctttctaaa aatttttcat
    20161 agcccatgac agagtagaaa gaataatggg gctccaaaat caagcaaata cactgttcaa
    20221 ttccgtctgc ttccatttga ccgatcacat ctggaataaa gggactggaa aacttattag
    20281 caaagtagac actgtattca ttccccagcc tagcttctac caaggcaacc tcttgacggg
    20341 taattttttg cagaggcgtg cctccaattc gtacataatt atcatagaga gtctgaatct
    20401 cgtggtcttg gggtctcacc ccacgacgaa tatttgtgaa aaaatcagct acaccttcaa
    20461 aggtaatctc ttctggtgaa ccgaaggtca tcattaaaat tgcttttttc atgactgctt
    20521 ccttgtgatg tttttatcaa gtttatttta tcattaatta atcgataagt aaacgctaat
    20581 atagggacat tctcaatctt ctgtcttttg tttttctctt ctttctatga tacaatggaa
    20641 aaaataaatt caaaaggagt ttttttatga cttatccaaa tctcttggac cgcttcttaa
    20701 cctacgttaa ggtcaacacg cgctctgatg aacactctac tactactcca agtacacaga
    20761 gtcaggttga cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt ggactgcaaa
    20821 atgtttacta tctaccgaat ggttttgcta ttggaacctt gccagccaac gatccgtctt
    20881 taacacgtaa gattggtttt atatcgcaca tggatactgc tgattttaat gctgaaggag
    20941 tcaatccaca ggtaattgaa aactacgatg gtggtgtgat tgaactaggg aattctggtt
    21001 tcaaactcga tccagctgac ttcaagagtc ttgaaaaata tccaggacaa acgctcatca
    21061 caacagatgg aacaagcttg ctaggtgctg atgacaagtc aggaattgct gaaattatga
    21121 cagccattga atatctaact gctcatcctg aaattaagca ctgtgagatt cgtgttggtt
    21181 ttggtccaga tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa gattttgatg
    21241 tggattttgc ctacactgtt gatggtggtc cactaggtga acttcagtac gagactttct
    21301 cagccgctgg tgctgaattg catttccaag gccgtaatgt ccaccctggt actgccaaag
    21361 agcagatggt caatgccctt cagctagcaa ttgattttca taatcaactt ccagaaaatg
    21421 accgacctga gttaactgaa ggttaccaag gtttttacca tctaatggat gtgacaggta
    21481 gtgttgagga ggtgcgtgca agctacatca ttcgtgattt tgaaaaagat gcctttgaag
    21541 cgcgtaaagc atccatacaa tctatcgctg ataagatgaa tgcagaactt gggagctacc
    21601 gtgtcactct caacttgaca gaccagtact acaatatgaa agaagtcatt gaaaaagata
    21661 tgactccaat taccattgct aaagccgtta tggaagatct aggtatcacg cctattatcg
    21721 aaccaatccg gggtggaaca gacggctcta agatttcctt tatgggaatc ccaactccga
    21781 atatctttgc aggtggcgaa aatatgcacg gacgttttga atacgttagc cttcagacta
    21841 tggaacgtgc agttgatacc atcattggca tcgtagctta taaaggctaa aaagacgagg
    21901 tagctcagct acttcgcctt tctttttatt ctactggttt ttcttgattt ccagtagttg
    21961 tagaagattc tgttgtttca ttttctgaag ttgattcagc aggtttagaa tctcttgtat
    22021 tgcttggttt gttttcgtcg ctagcaattt caatgttaga ttctgcagtt gcgtttggtt
    22081 ggttctcagc actggtgtta tcactatttg cttcagcatt tcttgctgga cttgtttctt
    22141 cacttgcgct agcttttgac tggatttgat gattcaaaac tagaatagct tttgtcgatt
    22201 caagtaaagc tgttttgtct ttactcttag cagaaagttg atctaataat gcatccacct
    22261 tatcaaagtc cgcatcagat ccattattac tttctaaata agagtgaagc gacatgagaa
    22321 tatcgtagag tttttgatag agtacaagtg tctgagaatc ttgctcagca ttttcctttt
    22381 cttgttgaag ggcgctagcg atacgagtca agacatcttt tacctgactg tttacttcat
    22441 ccaagtctgc atcagccttg tttgtggcag cttttagatt ttctacttct tctgccaagg
    22501 attgtctgat tccttcttca tggatttgtt ccaagagttg atttaccttg ctcaaaagac
    22561 tttctacttc ttccttgcta tctgtcgcag attattggtt gccatctacc atgtactcct
    22621 aaaacaggag agttataatc caagattaca aggccttaca gaaataagaa atccagataa
    22681 gacaatgttc gtccaagacg ctattcgctt cgcacagcag cacggattca atatgcttta
    22741 attttaaagt ttaggtgtca agacctcttt ttagtgtgcc caaaatttag agaagtaatc
    22801 aatcaactaa cttttatttt tttcaaactt tcagtaaact gacctaaagc taactcaatc
    22861 tgtctttgta gatgcttctg ctatcagcta gaagttgatc tacttttgcc aagactgcct
    22921 tctcatcaaa agttccaggt tgatagttgg attgcaggga tggaatcttg tttttcaaag
    22981 ccgcttcata tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca tgaggaatca
    23041 caaaaccttc tgaatcttca cttataattc gattggcatc aaaaccatga ccatcttctt
    23101 cctcatggtg gacatgtagt gacggattac ttaatacaga actagaagaa cttcctgcct
    23161 cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata taatgatagt
    23221 gatccccgtg tcttactata taagcatcac ctgtatctct gacaatatca ttagggttaa
    23281 agacataacc atcatctgct gcagaaacac cattattcgg tgtcaccgac aaagattgac
    23341 tgagagctgt agtattccct gataattata cttttgcagc tgctaattca cctgccgaca
    23401 agtcactctc aggaatgaaa tgatagtgac caccatgtgg tactatagta ggttgaaata
    23461 gaatatgagc aaattgataa ggggatttta aagtaatttc taacaatgat ttagaaacta
    23521 tgatgtgcta ttctaaattc aactcactat atataaccat catcggtagt ataacgtccc
    23581 tgtaattttg ctacagatac ttctgcacta gctcctttat cgtctttacc atgttcttgt
    23641 ttttggcgat tgatttcatc ttttgttcgt acattttctg catgagcttg atctttaagg
    23701 taaacataat actttccatc taccttaata atatatcctc ccttaaccta actgacgata
    23761 tcttgatctt tcggctgata gttgggggct ttcattaata gctcttcact aaagagcgca
    23821 tcaaaaggaa ctttaccatt atagtagcga taatgatcgc catgagaagt tacataacct
    23881 tgatctgtaa tcttaataac aatttgtttt gcttgaattc cttctttttg actaacctag
    23941 tctggagtca aattttcagt cttcttagtg tctttattac tgtttacata tgaaacacga
    24001 tttttatctg tattggcctg ttagctatgt tggttcagag tataaacaca cagacttaag
    24061 gaaaggataa caacagatcc agc
//
LOCUS       DAVLTG010000027        24075 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLTG010000027 DAVLTG010000000
VERSION     DAVLTG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.027"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            60..971
                     /locus_tag="VYN12_001201"
                     /pseudo
     CDS             60..971
                     /locus_tag="VYN12_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1088..1435)
                     /locus_tag="VYN12_001202"
     CDS             complement(1088..1435)
                     /locus_tag="VYN12_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1415594.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1546..3321)
                     /gene="spxB"
                     /locus_tag="VYN12_001203"
     CDS             complement(1546..3321)
                     /gene="spxB"
                     /locus_tag="VYN12_001203"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1415595.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3528..5771)
                     /locus_tag="VYN12_001204"
     CDS             complement(3528..5771)
                     /locus_tag="VYN12_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1415596.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5781..6152)
                     /locus_tag="VYN12_001205"
     CDS             complement(5781..6152)
                     /locus_tag="VYN12_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1415597.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            complement(6163..6558)
                     /locus_tag="VYN12_001206"
     CDS             complement(6163..6558)
                     /locus_tag="VYN12_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1415598.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6742..6840
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6924..7715
                     /gene="thiD"
                     /locus_tag="VYN12_001207"
     CDS             6924..7715
                     /gene="thiD"
                     /locus_tag="VYN12_001207"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1415599.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSGIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7925..8557)
                     /locus_tag="VYN12_001208"
     CDS             complement(7925..8557)
                     /locus_tag="VYN12_001208"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1415600.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8550..9353)
                     /locus_tag="VYN12_001209"
     CDS             complement(8550..9353)
                     /locus_tag="VYN12_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1415601.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9353..9877)
                     /gene="thiW"
                     /locus_tag="VYN12_001210"
     CDS             complement(9353..9877)
                     /gene="thiW"
                     /locus_tag="VYN12_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1415602.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9882..10574)
                     /gene="tenA"
                     /locus_tag="VYN12_001211"
     CDS             complement(9882..10574)
                     /gene="tenA"
                     /locus_tag="VYN12_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1415603.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10585..11235)
                     /locus_tag="VYN12_001212"
     CDS             complement(10585..11235)
                     /locus_tag="VYN12_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1415604.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11237..12622)
                     /locus_tag="VYN12_001213"
     CDS             complement(11237..12622)
                     /locus_tag="VYN12_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415605.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLNGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12623..13183)
                     /locus_tag="VYN12_001214"
     CDS             complement(12623..13183)
                     /locus_tag="VYN12_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1415606.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13445..13533)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13742..14371)
                     /locus_tag="VYN12_001215"
     CDS             complement(13742..14371)
                     /locus_tag="VYN12_001215"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1415607.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     ESALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14373..15155)
                     /gene="thiM"
                     /locus_tag="VYN12_001216"
     CDS             complement(14373..15155)
                     /gene="thiM"
                     /locus_tag="VYN12_001216"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1415608.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVVSKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            15246..15332
                     /locus_tag="VYN12_001217"
                     /pseudo
     CDS             15246..15332
                     /locus_tag="VYN12_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(15482..16150)
                     /locus_tag="VYN12_001218"
     CDS             complement(15482..16150)
                     /locus_tag="VYN12_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1415609.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(16365..16453)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16707..17843)
                     /gene="lctO"
                     /locus_tag="VYN12_001219"
     CDS             complement(16707..17843)
                     /gene="lctO"
                     /locus_tag="VYN12_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1415610.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18468..19958)
                     /gene="lysS"
                     /locus_tag="VYN12_001220"
     CDS             complement(18468..19958)
                     /gene="lysS"
                     /locus_tag="VYN12_001220"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1415611.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(20085..20231)
                     /locus_tag="VYN12_001221"
     CDS             complement(20085..20231)
                     /locus_tag="VYN12_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1415612.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            20446..21126
                     /locus_tag="VYN12_001222"
     CDS             20446..21126
                     /locus_tag="VYN12_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415613.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            21086..21466
                     /locus_tag="VYN12_001223"
     CDS             21086..21466
                     /locus_tag="VYN12_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1415614.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            21476..21763
                     /locus_tag="VYN12_001224"
     CDS             21476..21763
                     /locus_tag="VYN12_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415615.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            21764..22521
                     /locus_tag="VYN12_001225"
                     /pseudo
     CDS             21764..22521
                     /locus_tag="VYN12_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22533..23394
                     /locus_tag="VYN12_001226"
                     /pseudo
     CDS             22533..23394
                     /locus_tag="VYN12_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(23474..24028)
                     /locus_tag="VYN12_001227"
     CDS             complement(23474..24028)
                     /locus_tag="VYN12_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415616.1"
                     /translation="MIGITGANGSGKSVLFKLIAGLYSPSYGEVLINGENIVPERKIP
                     ANLGALIEEPGFINYYSGFKNLQYLASIRGVVGNQEISDTLKIVGLYEQKDQKVKTYS
                     LGMRKKLGIAQAIMENPSILLLDEPMNALDKSSVENMRTLFRKLSSEKGTTILIASHS
                     EEDIRILCDKVYAIEDKVCTLCSD"
BASE COUNT         7205 a         5248 c         4462 g         7160 t
ORIGIN      
        1 aaactaattt atagaaatat tttagcagct aaggtgtact gttatagatt caatacacta
       61 tagactgtaa tcaaacaacg atttggcgaa atgtaaaaaa atatgaggag ttcgaactcg
      121 actctctcct tcaagaaaca cgtggtggcc gtaaccatgc atatatgacg attgaggaaa
      181 agaaagtctt tcttgcccgc catttgaagg ctacagaggc aggagaattt gttacaattg
      241 atgccttatt tcaggcttat aaaaaggagt taggtcgttc ctacacacgt gatgccttct
      301 atcaactgtt gaagcaccat ggttggcgaa atattatgcc acgtccagaa catcctagga
      361 aagcagacgc tcaaaccatt gtcgcgtcta aaaataaaat ctcaattcaa gaagaaaaga
      421 aagcgcttta aaagcagtag acgttttcgt aaggttcgct tgatgtacca agatgaggct
      481 ggtttcggta gaatcagtaa actgggatct tgttgggctc caataggagt aggtccacat
      541 gtccatagtc actatatacg agaatttcac tattgttatg gagctgttga tgcccataca
      601 ggcgaatcat ttttcttaat agctggtgga tgtaatactg agtggatgaa cgccttttta
      661 gaagagcttt cacaagctta tccagatgat tatcttttac tcgttatgga caatgctata
      721 tggcataaat caagtacctt aaagattccg actaatattg gttttacctt tattcctcca
      781 tacacaccag agatgaaccc attgaacaag tgtggaaaga gattcgtaaa cgtggattta
      841 agaataaggc ctttcgaact ttggaagatg tcatgaatca acttcaagat gtcatacaag
      901 gactggagaa ggaggtgata aagtccatcg ttaatcggag atggactaga atgctttttg
      961 aaagcatatg agtattatat gcaatttctt tatataaaaa gaccggattg ctccgatctt
     1021 tcaatagttc atattctcaa tttctatttt aaaaatagct aaggttaacg tcaaatgact
     1081 acgcgaccta tttcatacga taaaaatcaa gcactagacc agcaggtcct tgaactaata
     1141 aggactctgt tccccaatcg gttacagttg gtccgtgtaa aacctttata ccaagctcgt
     1201 tcaaccgttt gtagttctgg tctacatcct caacctcgat atgaataatg attcctgact
     1261 gaaagttttc caaaggaacc aaatgatttt gtgacaacat aaggcagtga ctaccaatcg
     1321 taaactgagc aaaaccatca tcagcataat ctgccttttt atccaaaata tgctccaagt
     1381 cagcacagac ttggggaaca tttgaaacga taatatctaa ttgatttaaa ttcatttact
     1441 ctcctccata aaaagaccgg attgctccga tcttttaaag ttctgctcta tgaaaatcaa
     1501 agaataaagt ctacaagttt catatttgat tttcggcgag aggaattatt taattgcgcg
     1561 tgattgcaat ccttcttctt ccaagaagag acggaatggt acgagttctt ctgcttcgta
     1621 tttttccttg aaggctttga tagcttcttc tgagtgaagt tttggatcca attcaagtac
     1681 ttctactgga agtggacggt gttgagtgat gcgagcatcg atgacaacag ttttaccttc
     1741 tttgttcaat ttaacagctt ctgcaacaac tgcatcgatg tcttcgatac ggtcaactgt
     1801 gaatccaaca gctccttgag cttccgcaat tttagcgtag tcagcgtttg tgaagtctac
     1861 accaaacaag tgtttgtttg tatcttcgta tttgttcttg atgaagccgt actcagcatt
     1921 tgagaagaca aggttgataa ctggaaggtc gtattgaacg tttgtgataa cgtctgggta
     1981 gcacatgttg aatgctccgt cacccatgat gttccatact tggcgatctg gattgtcttt
     2041 cttagcagcg ataccaccag gaagggcaat acccattgtc gcaaagagtg gagatgtacg
     2101 ccacatgttc ttaggtgtca tgtgaaggtg acgagtagat gtttgagtag tgttacctac
     2161 gtcgattgag tagatagcgt cttgatcagc atgtttgttg attgcattgt aaacttgata
     2221 caattgcaat tcaccctcag ttttaccttc gagtttgttc atgtaatcac gccagttttg
     2281 gttgttctta acgtttgcac gccaccatgg agttgattca actgggttta ctttgtcaag
     2341 gatagcttta gctgcttgac cagcatcacc aaggattgaa gcgtcaaggg catgacgttt
     2401 accaagtttg taagggtcga tatcaacttg gatgaatttt tcagtgttct tgaatgcttc
     2461 gtaaacttca gcaaatggga agtttgaacc aaggaaaaga actgtgtctg cttcaaagac
     2521 cacttcgttg gctggtttcc aaccaacacg ataagcagaa cctgtcaaac cttcatagtt
     2581 ccattcgaaa gcttcaaagt ttttaccagt tgtgatgatt ggtgctttga ttttacgtga
     2641 caattcagta atcacttcac cagctttaac accaccaaat ccagcataga taactgggcg
     2701 ttcagcattg ttcaagattt caacagcttt gtcgatttca acttcgttca aagcaggagc
     2761 gatgaatgag cgttcgtatg aacctgaacc gtagtatgag ttttcgtcga tttcttggaa
     2821 accgaagttt actggaattt caacaacagc tggacctttt ttagaaactg cagcacggca
     2881 ggcttcgtca attacttttg gcaattgctc agcgtaagct acacgtttgt tgtaaacagc
     2941 gataccgttg tacattgggt tttggttaag ctcttggaaa gcatccatgt tcaattcgtt
     3001 aactggacgt gatccaagga ttgctaggaa tggagtgtta tccatagctg catcgtaaac
     3061 accgttaatc aagtgagtcg cacctggacc acctgaacca actgcaaccc cgattgagcc
     3121 gccgaattta gcttgcataa ccgctgcaag agcacctgtc tcttcgtggc gaacttgtaa
     3181 gaagcggata tctttgtctt cagccaaagc gtccatcaat gagctgagtg ttcctgatgg
     3241 gataccgtag attgtatcta cgccccatgt tttcaatacg ttaagcattg ctgcagatgc
     3301 agtaattttc ccttgagtca taatgataac tctccttcaa tttttttaga cttggagaat
     3361 acgattacat agaattggaa acgttctcca aatttttact attccactgt atcatattta
     3421 tgctgacttt tctaaaaatc tgctcaaaac tctctattct ctattctaat acagttttga
     3481 aagtgtcgtc atttctgttt tataacaaaa aaatctagtc attactttta gtctatttta
     3541 ctaaaattta acagaaggga actggtcaga acagatacag aactaaaggc catggctaga
     3601 cctgccaatt ctgggttgag agccagtcca acacctgaaa agactcctgc tgcaatcgga
     3661 attccgacaa cattgtagat aaaagcccag aaaagattga gcagaatacg atgaaaggtt
     3721 ttcttactca tgtcgaaggc acgcaccact cctaaaagat tattggttgt caacaccaaa
     3781 tctgctgact cgatggcgat atctgttcca gctcccatag caatccccac atctgctaca
     3841 ctaagggcag gagcgtcatt gatcccatca ccaacaaagg ctactttacc tgactgttgc
     3901 agtttatgga tttcatgggc tttttcttct ggcaagacgc ctgcaatgac ctcttcaatt
     3961 ccgatttgat ctgcaatagc acgcgccaca ccagcattgt ctcctgtcag catgactgtc
     4021 ccgagaccac gtttttttag ctgactgatg gctagcttag catttttctt aggaatatct
     4081 tgcaaagcaa gcaagccttt gatttcattg tcaacagcta agaacacaac tgtcttagct
     4141 tctttttcta gttcttctag tttatcttga taagtattag aaatatccat gccatccagc
     4201 attttagcat ttccaagtaa aacttgtttt ccattgattc gccctgaaac acctttcccg
     4261 tgcaaggcct gaaaattttc aacagtttga aactcaagtc cagcttcact cgctcgctta
     4321 acgatagcct cagccagtgg gtgttgagaa gcatcttcca aggaggctgc caatccaaac
     4381 acttctactt cgtcgccgat gacatctgtt accacaggtt tcccttccgt caaagtcccg
     4441 gtcttatcaa agacaagggt ttgaactttc tggatttcct gtaagacagt tccatttttg
     4501 aggagaaccc ccatcttggc actacgtcct gtccccacca taagggctgt cggtgttgca
     4561 agtcccaagg cacaaggaca ggcgataatc aaaaccgcca ctccgtagag aagagaggac
     4621 acaaagctag ctccaagcac aaccacacta tccctgagca agacgaacca aacccaaaag
     4681 gtcatgattc ctaaaatgac aactactggg acaaaaatcc ctgaaatctt atccgtcaag
     4741 tcctgaatcg gcgcacgact tgtctgagct ttcttcacaa aatccacaat ctgagccaaa
     4801 acagtctctg agccaacttt ttctgctcta aagacaagcg ttccactatg attgatggtt
     4861 gagccaatga cagtatctcc aactgtcttg tccacaggca gactctcacc tgtcaccatg
     4921 gattcgtcaa tactagagac accttctact acgacaccat caacagcaat cttttcaccg
     4981 ggacgcactc gaatcaggtc gcctaccttg acttgttcca aaggaacttg gacataacta
     5041 tcatcactca agacttctgc ggttttagct tgcaagtcca gtaatttctc cacagcttgg
     5101 gacgtatttt ttctcatttt ttcctcaaaa actgctccca aaagaacgaa aaagaggata
     5161 aatccagcac tttcgaagta aacagggaga ccagcaaaga gagcaactag gctatagaaa
     5221 taagccacta gagttcccag cgcaaccaag gtatccatgt tggcattgtg ctttttaaaa
     5281 ctggcccaag cactctggat atatggctta cctgcaacta acataatagg cgttgttgct
     5341 agaaaggttc cccaatgcat gacttgatga ctaatgctac ctgccaacat cccaatcatg
     5401 agaatcacaa gaggcacagt acagatacta gtaatccaaa aacgttgcag gagagataga
     5461 gattttcgag tcttctcaac gactgtatag cttccctttt gcatcttcat gccacaagaa
     5521 aattcatgtc gccctaattc ttgaggtgta aaacgaatga ctttctcctc atctacgccg
     5581 attggttcca agataccttc ttcttcaaac agaatttcct tataacagtt tgaaggagta
     5641 gcacgatgaa aggtaatctc agctggaatt cccttttgaa gctggatatg ggctggatga
     5701 tagccttttt cagcttggat acggattttt tgaatgccat tttctaagct tgctttcaca
     5761 atttctgtca tagtctccac ctactctaca atcatcttgc cgtgcatcat gttcatacca
     5821 caagcaaagc taaactctcc agcctgttca ggcgtgattt ccactacata ctcttccccc
     5881 attggcaggt tcgcatgtac accaaaatct ggaaaaacaa tttgatccag acatggtgaa
     5941 ggatccttgc ggtcaaagac aatgcgggct ggcactgatt tcttgaggac aatcaactca
     6001 ggagtatagc ctcccatgac ttccactcga atctcttggt atccgttttt ttgctgggct
     6061 ttttgtccag atttttcagg ctttttgaaa aaccaaaaca agataaacgc gataagggca
     6121 atacaaataa tggttacaat actatttaac atgacgtctc ctttacatac aattacatct
     6181 tacttctgtt acagcacttg atttcttctc tgaaatcaca gcttccaagt cttccaagtc
     6241 agtctgagta aattcacatt ctacaatcaa gtcagccaac aaattcctaa tcctacggga
     6301 acaaaccttg tctttgatat cttggacaag taaatcccga ctttggtcta gagttaaaag
     6361 cgctgaataa acaaaggact tgccttcttt tttccgagtc aaacactctt tctcaactag
     6421 acgagccaaa agtgtctgaa ccgtggactt ggaccagtca aaccgctctg ccaaaaccct
     6481 aatcaaatct gtactggtct gctccccctg catccaaata atcttcatga cctgccattc
     6541 tgcatctgaa atctgcatta ccatacctcc aaaatctaca tttgtcaatt acactcaaca
     6601 gtatactccc aaaatctaca tttgtcaatt atagaaataa tattttcttc gaaaaataga
     6661 attttaatca tttgaaaaac gatttgcagt caaatattac tatataaaca ataaaaatat
     6721 gctatactaa agaaaaaaga aaacaaccac taggggtgcg taaagctgag attaacgact
     6781 gttagatccc tctgactcaa tctaggtaat gctagctgat ggaagtggaa atgataatgg
     6841 ggactagcag tcttctattg cctttctaaa acagactagc ttgttcttaa gaatacaaac
     6901 ttcagttggt tgggaggttt tagatgactt atttacccgt tgctttgacc attgcaggga
     6961 ctgaccctag tggtggtgct ggcattatgg cagatttaaa gtcattccaa gcgagagatg
     7021 tctatggaat ggctgttgta accagtcttg tcgctcaaaa taccagaggt gttcagctaa
     7081 tcgagcacgt ttctcctcaa atgttgaaag cccaattgga gagtgtcttt tctggtattc
     7141 cacctcaggc tgtaaaaact ggaatgttgg ctactactga aatcatggaa atcatccaac
     7201 cctatcttaa aaaactggat tgtccctatg tccttgatcc tgttatggtt gctacaagtg
     7261 gagatgcctt gattgactca agtgctagag actatctcaa aacaaactta ctacctctag
     7321 caactattat tacgccaaat cttcctgaag cagaagagat tgttggtttt tcaatccatg
     7381 accccgaaga catgcagcgt gctggtcgcc tgattttaaa agaatttggt cctcagtctg
     7441 tggttatcaa aggcggacat ctcaaaggtg gtgctaaaga tttcctcttt accaagaatg
     7501 aacaatttgt ctgggaaagc ccacgaattc aaacctgtca cacccatggt actggatgta
     7561 cctttgctgc agtgattact gctgaactag ccaagggcaa gagtctttac caggcagttg
     7621 ataaggccaa ggcctttatc acaaaagcta ttcaagatgc ccctcaactc ggtcatggtt
     7681 ctggtccagt caaccataca acttttaaag attaagaaaa aaaactctct agttcccact
     7741 ttaagggaat tagagagttt ttatactctt cgaaaatctc ttcaaactac gtcagcttcc
     7801 atctgcaact tcaaaacact gttttgagct gacttcgtca gtcttatcta aaacctcaag
     7861 gcagtacttt gagcaacctg cgactagctt tctagtttac tctttgattt tcattgagta
     7921 ttaattagga aagaatgtca tgcaactttg ttaaaaaggc ttgcgttttt gcctcaatat
     7981 cttctgcttg catcaaatca cgtacaacag ctacaccagc tatgccagtg cccataagct
     8041 gatcaatatt ctccgaagtc aagccaccaa tagcaactat tggaatggca accgtttggc
     8101 aaattgtttt caaggttgaa atcagggtga tgggtgcatt ttccttggtg gttgtcggaa
     8161 aaatggctcc tgtccccaag taatctgcac ctgatttctc cgcttccaga gctcttttaa
     8221 ccgttttagc ggtgacaccg aggatttttt caggacccaa gacttgtcgg gcaaccgaaa
     8281 ctgggagttc gtcatctcca atatgcagac cagcagcatc aaccgcaaga caaacatcca
     8341 accgatcatc gattatcaag ggtacctgat aagcatctgt tatttccttg acttgttttg
     8401 ccagttgata atattgattg gttgtgagat ttttttctcg caattggact atggtaaccc
     8461 ctgaacggca ggccgtctca acttttgcaa gaaagctttc cacggaatct tgatagcgat
     8521 tggttaccag atatagtcta agtgcttctc tattcataaa cctctccttt gatggtatct
     8581 agccaatttt catctcttct taggagcgaa agctgattga gtacttggta acgaaattct
     8641 tccaatccca ttccttgaac aactattttc tcagcagcga tattgagata agagactgct
     8701 aagcaagaag cttcaaaacc agtctttcct tggctgagaa aaacggctgt taaggctcca
     8761 accaaatctc ctgtccctgt tatccagtct aattctgcac agccatttcc cagtacagcg
     8821 acctgatttt tcgaaacgac gaggtccttg ggacctgtga ctaagaaaga cataccatga
     8881 taggtctgac accagtcttt caagacttga agcaaatcct ccgtttcttg atctttagca
     8941 ctcgcatcga ccccaacgcc gtggtgcttt aatccaacaa gacttcgaat ttctgacatg
     9001 tttcctttaa ggaccgtagg tctatagtct aaaaggtctc tgactaagct cttacgaatg
     9061 gatgaagctg ttacgccaac cgcatctact accattggga gacaaacttg agctgcataa
     9121 gaagctgcta tacggattgc tttctccttc tcagctgaca aatgccccaa attgatgaag
     9181 agagcctgac tttgcttagt aaaatcaaga acctcacggg gatcatctgc catgacaggt
     9241 ttgcatccca gagccaaaat cccatttgcc agcatctcac aagaaatctc attggtcata
     9301 cagtgaatga gggaactaga gcctatagga aagggatttg taaattcctg catcagtcta
     9361 tcctttcact aaagaaatat ccctgcactt ttttaaagaa ttcctgcttg attaaaaatc
     9421 gaaaggcaat aaaggaaatc gctgtaccaa tcaaggttgc tccgaaaaat cgaggcgtgt
     9481 agataaacca gctaagctta gcagctgatc ctgtaaagag taccataaca ggataggaaa
     9541 caatagaacc aataatacct gttcccacaa tttctcccaa ggcagaaaag taaaattttc
     9601 gaccgtactt ataaaagaga cctgctagaa gggctccaaa agtcgctcct gtgagagcta
     9661 aaggcggaat cccttgagtc gtcatacgga taaaggctgt cactgtagcc atagccaagg
     9721 cataaacagg tcccatcatg attcccgcta gaatattgac tacactggac atcggtgcca
     9781 ttccctcaat ccgaaagata ggtgtaagga ctacatcaag ggcaatcatc atagataaaa
     9841 tggtcaattt gtgaacttgt agttggtgct ttctcatgtt tctattcttc tcctttttct
     9901 aaagactgta aatcgctctt ccatgtctgg tgttggtaag ccatctccca aaacttggct
     9961 tccatatgaa cactgatgtg gaaggcatct agcatttttt gcttatctgt ctcatcactt
    10021 tctcgataga gctgattgac cagtgctccc tcctctctga tctgttgctc taactcatcc
    10081 gtaatataag tttcaatcca ttgttgatag agaggatttg gtgatggttt aagattaagt
    10141 gatttgccta tatcatggta taaccaagga caaggaagca agcttgcaaa agcgatggct
    10201 aagttcggtt ctgcaaattg cctataaata tgagaaatgt aatgataaca ggttggagcg
    10261 attggatgtt gctccatttc ctggtcgctg atttccaatt ccttgaaaaa ttgttggcga
    10321 ataaataact caccctccac taaaccctga gcattttgtt tcaagagtct tttcatctct
    10381 tggtttgaag tcttatcagc caaaagatga tagatttctg agaaagcctt cagatagtag
    10441 gcatcctgaa tcaggtaata gcggaaaatg gcaggttcta aattcccctc ttgtaattgt
    10501 aaaataaagg gatgatgaaa ggaagcctgc caagctttct tggataattc catcgcaata
    10561 tctgtaaatt ccataataac tcctttataa aaatagactg gtttgaagca ataaaaagaa
    10621 aagcaggtag attaattttg tttttttagg aatataaaaa gtccgatagc tattcttcaa
    10681 ctgtgcatgt tcgtcatatc cgtgagcaga tagagctctc aggtaaagat ggcgccacct
    10741 aaagactgtc atcagaacct tactgtaaat caagggcgac caaaaatgta gttcttgacc
    10801 acgtaatagg caagcttctt tgagggactt gatttcttgc tgaatgagag gaaaagaatt
    10861 gaataccaca atcaaggcat aggaccaaga gcgtgatagc cccttttgag ccaagtacaa
    10921 gagaagctct tttagtgaaa tagaggaaac aaagacaagg ccgatacaaa ctgtcacaaa
    10981 ggccctcgtt ccaagcatga ctgcctgtga agcatctccg tgtaactgaa ctgcccagta
    11041 gttggcaaaa gatggtaaaa tggcaagtat gatcatccaa gctaacattt taaatcgacg
    11101 gtaatagagc ataaagagaa tacaaaatgc gactaccgaa agattcagag caatcgaagg
    11161 aatgaaagat gtttccaagg ataaaatcag caagaagaga ctgataatcg gtgtctgggt
    11221 tgctactttg accatactat ctcacctccc cttgggtatt gctactctga gatgtaagtg
    11281 gtttggtaat ggtcacttct ttcacatgcc gaagaccctg actagtcatc tcaatccaat
    11341 aatcaaccac agaaatcaaa gggtctaaac gatgactaat gagcagaaaa cttcttcctt
    11401 gattcctctc ctccacaatc cacttgcaaa aataatggca ggctctatca tccaaacctg
    11461 caaaaggttc atctagcaag atcacggaag ccttactggt caagatggtc aggagctgaa
    11521 gaattttttg ctgaccacca tttaattgat agggactctt atcgactgcc tgctccaaat
    11581 caaaatatcg taaagcttga aaaatccgct gatttctttc agaatcaggt ccatctaatt
    11641 gaagctcctc tcgcagactg actcggataa actgcttctc agcttcctga acaacaccag
    11701 tcagatcacg atacaaactc tttttctttt tcaggaccga acccttccat gcaatgcgcc
    11761 ccttatactt ttgaaattga agaatagacc gaaagagggt tgatttcccg acaccattgt
    11821 cacccaggat acaggaaatc ccttgataga atgtgaaatc agcaattgaa aagagggggc
    11881 gatttccaaa ctcacaagtc gttctatcca tatggaatag ttccgggcta gaagcaactt
    11941 cctttgaagc aacctgtgtc atctcatagg aagggatttg aaacacttcc cttagttttc
    12001 cgtctcttag ctcaaccata tggtcgatat aggctttata gtcagataaa tcatggtcgc
    12061 acaaaataac tgtctttcca tcaagagcca actcttttag aatctccaat atctcgattc
    12121 tgctcttgcg gtcaatggaa gcaaaaggtt catccaagag atagacccta ggattcatgg
    12181 caaagaggac agccagcgct gctttttgct tttccccacc tgataggtga tgaatgggac
    12241 ggtgtaagat tgcctcgcaa cgacattgct ggacaacctc tgctatttta gaatcaattt
    12301 cctgaaggtg atagccgata ttctccaagg tgaaaatcag ctcctcaaac aagctctcca
    12361 tggtaaattg atgattggga ttttgaaaga gaatgccaac cttctggaca cgtgcgatga
    12421 tagaaagttg actgacctcg ctcccatcta tcaggacttg accactatag ggaagagaac
    12481 tgacttgggc aatcatttga aagaggctgg attttccaga cccactactc ccaactaaca
    12541 aggtaaaggc ttgcgcatga aaagtaaaat caaacggctc agagaagatt ggggactgaa
    12601 tcgctcgtag ttccagaccc atctatgctt ttcctccagt tgcaaactga tgatagagtt
    12661 tgacaatggc acgaaccaag atggtacaga agaaataaac agaaataaaa cgtaccacaa
    12721 gtaaggaaag gacaaacgga agggaaaagg cgtagtaacc taacttaatg tattcataga
    12781 caaagctaac aagcgtaatc ccaatactat tagcagttag agagagccaa ctttcatagc
    12841 gattcttagt tacgataaaa ccaaattcac ttcccaaacc ttgaaccaag ccagacaaaa
    12901 gagctcctag accaaattgg ctaccataaa ggacttcagc aagcgcagct agcacttctc
    12961 caatcgttgc acttccgact ctcggaacaa agatggcagc aatgggcgca gccatacacc
    13021 agagaccgaa gaggatttca ttggcaaagg cctgcaaacc aagaggtgtt aagagtagac
    13081 tgagaatatt atacacatat cctgaaccaa cgaaaacccc accaaaaaag atagacaaga
    13141 aagcaagcaa gataacatct tttaactgcc attttttcaa cataaaaaac tccttttttt
    13201 aaagaaaagt ggggcactca agaagaccga cctaaatact ttgtatagca gactgaattt
    13261 agaacagtac acaagaatgc taaaatattt ctagaaatta atttgaattt tctaattgat
    13321 ttgttcgcat cttatttcaa tctactatat catcttcatc cagtttcgta aaagaaaaaa
    13381 ctctaattac agatacgaat tagagttcag cttacaagat tagacagttc ttttcgacat
    13441 acgaaaaaaa catttcacat ttcccttcgc cagtcttaac tgtatcaggt tcaatgggta
    13501 tcatctcagc ctaaagcacc ccaaatgtct ttattattta attatgtgat tattataaca
    13561 cacattttat actagttcaa gaaattgaac tggaaataca gccttgcact cacaaagaca
    13621 gcagatcttt cttttgcaaa aaacaaatga cctgtttgat gaattagcca ttcaagctga
    13681 atctagacat agctttttaa aaaaggaaaa tcctacttac ttagaatcca aggatagata
    13741 tctattgttc actcatttcc cgaacagttt tttctatatt ttttgcatac gatattgccg
    13801 aaatgattga aacgccgtca acattggtct ttataatgtc tttaatatgt ttcgtctgta
    13861 tcccaccaat tgcaactaaa ggcatttgtg gcaatagttt tctcatcaat tcaagacctt
    13921 cataacctat agcaccacca gcatcatctt ttgactgggt atcaaataca ggcccaacac
    13981 ctacataatc tacatattca acttttgatt gttgaaattc ttcttcgttt cttatagaaa
    14041 gaccaattat tttatctggc atcaattttc taatttcatc aacaccaata tcatcttgac
    14101 caacatgtac gccatcggcg tcaatttcca ttgctaaatc tatatcgtca ttaacgataa
    14161 atggaacatt gtatttttta caaagttctt taatttggat agctagctca agtttttcta
    14221 agccttctaa agcactctca cctttttctc gaaattgaaa taaggttata ccacctttta
    14281 aggcttcctc aacgactgta tatagatttt ttccttggca agtagtcgtt ccacaaataa
    14341 aatatagttt tagtaattct ttatgaaaca tcttacttca ctcttttgaa ttcctttaca
    14401 tcttcatctg taatctcgta taaggcattt ataaattcaa ctttaaatgt cccaggaaga
    14461 tgtccatttg gacgtttttc tgccatttct ccagcgatat tgtaaaccaa cattgctgtt
    14521 tctaatgatt tcaattcttg acctttttct agtccgataa agcttgctac tacagctcct
    14581 aataagcatc ctgtcccaat gactttcggc atcatagcac taccattatg aatcgttacc
    14641 acttctccat taacagcaat ggcatccact tcacctgtta ctactattgg aatattgaac
    14701 ttctcatttg ctgctagagc aatttcgtca atattatcta cgcccgcact atctactcct
    14761 ttagatacca catctattcc tactaaagag gcaatctcgc cagcatttcc tctaatcgct
    14821 gctagtttat aattgttgat tagatcatct gctacttttt ttctatattc tcctgctcca
    14881 caggctacag gatctaaaac tgctgggaca ttatatttct ccgcaatttt cagagcagct
    14941 tggtataatt tccaattttc atctgtcaat gttcctatgt ttattaataa accaccagca
    15001 tactttaaca aatcctctaa atctgctgga aactcactca tggctggtga gacgcccagt
    15061 gctactaatc catttgctgt gaaatttttt actacatcat tggtgataca aatgaccaat
    15121 ggtgcttttt cttttaataa ttttaaactt gtcatattga aatccttcct tttcacttta
    15181 tacgatctac tgatttcgat ttatctctat ctttcgttaa gaaatttttt tcatttacgt
    15241 tgaatgattt atactcaatg aaaatcaaag agcaaactag gaagctaacc gcagattgct
    15301 caaaacactg ctttgaacct gtagataaga ctgacgaagt cagctcaaaa cactgttttg
    15361 aggttgtgga tagaactgac gaagtcagta accataccta cggcaaggtg aaactgacgt
    15421 ggtttgaaga gattttcgaa gagtattacc tcatcaaatt tgtaaatatc atgagccttc
    15481 tctagacatc gtaaccaata tcaaaaaaag ctaattctaa agcgactgct tgattccagc
    15541 gttgctgaag ttctgtcaaa tcttctcgat ttttaccgac acgattgagt tcgtcaacca
    15601 gaaattgaac ccactctgca aagaaaggac ctctgtggag attgatccat tccgaatgaa
    15661 tatagacttc aggtaaagcc aaatctttag aaccccagtc taaatagaga ccttctgcaa
    15721 tgaccagcat gaccaaaaga tgggcatagt ctgatgaagc caccgccgaa tacattagat
    15781 cctgaaaggc ttttgttaca gggtgcaaag tcacttctag atagtcattc tctgctactt
    15841 ttaactcttt aaaagccttt tggaaataac catcttcatc tgcttcaaga aagcctagtt
    15901 gcttggcaaa acgaagcttg gattcaagtt tatctgcgtg agctacgcag gcacccagca
    15961 tggataagaa ggcatcaaag aagtgataat cttgaatcag atagtccttt aagaccttat
    16021 tctcaattgt ccccgcaaaa agttccttaa caaaacgatg attgattgca gcctgccaat
    16081 ccttctgact gctttttaat aattctccaa cagtcaaacc tggctgaaat gcatagtctt
    16141 gtgtttccat atttacttct cctctcttta cttgttagta attaataaaa caccaagaaa
    16201 tatcaagcaa aatcgtaatt ccacttgatc cttttaaaac acatcgagag tatttgcaga
    16261 gagctaacta aacaagccta tccagtttat ataaacaaaa aactccaatt acaatcaaga
    16321 attagagttg acttacaaga ttagaccgtt catttcacca tacgaaaaaa ctgttcacat
    16381 ttcccttcgc cagtcttaac tgtatcaggt tcaatgggta ttatctcagc ctaaagcacc
    16441 ccaaatgtct ctattattta attactgaac cagtatagca aaaaatgaaa gccttagcaa
    16501 gatatttaac cgaaaaatat ctttatatat agtagattga aactagaata gtacccctct
    16561 acttctaaaa cattgttaga aatcgattta actgtcctga ttgatttgtc ctattcttat
    16621 ttcattttac tatagttttc gatagcgatt tattcttcca atacacgaag aaaaacctcc
    16681 acattcagtg aaggcaatct gttttatcaa tacaatttta agtcacgagg gtcaactggg
    16741 aaggttgggt tgtatggatt gtgacggagc ttaaagtgtt tgacatcttc aatggtctga
    16801 gctccagaca attgcataac tgtcttcaat tccgcattca agtgttcaaa gacttgacgc
    16861 acaccgacac taccaccgag agccaagcca taaataacag ggcgaccaat agctaccaag
    16921 tctgctcctg aagccaaggc tttaaagacg tgttgaccac gacgaacacc agagtcaaag
    16981 acaatcggca cacgtctatc aactgcttct gccacttctt gaagcgagtc aaaggcagct
    17041 ggtccaccgt cgatttgacg accaccgtgg ttggttaccc agataccaga agctcctgca
    17101 gcaagtgaac gttcaacgtc ctcacggcat tgtggtccct tgacatacac aggaagacca
    17161 gagtattcag cgataaattc tacatcgcgt ggagacaagc gttgtttagc tgatttgtaa
    17221 acaaagtcca ttgatttacc agcaccttct ggcaggtatt cttcaacaat cggcatgcca
    17281 actgggaaga caaaaccatt acgcttatcc acttcacgat tcccccctac agtagcatct
    17341 gccgtcaaga caatcgcttt ataaccttca gccttcacac ggtccatgat gtggcggttg
    17401 ataccgtcat ccttactaaa gtaaaattgg aaccaatggg gtgtcccttg aagggcttca
    17461 gaaatctctg gaaggtcaac agtagagtaa gagctggttg tataaagaga accaaactca
    17521 tgcacaccac gcgcagtcgc cacttccccc tgttcatttg ccaatttatg agccgcaaca
    17581 ggcgccataa tgattggtga agatagtttt tcacctgcaa attcaatctc tgtacttgga
    17641 ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt ggttaaaggc gcggatattc
    17701 tctcttaaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc tgctttagga
    17761 ataacttgtt gcgccattgg ctccaaatca taggtattga tgaagtctac atgaccttct
    17821 gcattgcttg ttttgtatga cataaaatgc cctccttgat taagtaagcg tttgcttttt
    17881 actacacaac tataataact cttttttcaa tcattttcaa gagttttgct taaaaaccat
    17941 cttatttttt catacaatat actagcccta ctttccttaa actctaaact ttagtctata
    18001 ttaagtgaat cgttgagatt ttttgctgcc aggcatttga actacttttt tatttgcgga
    18061 ttctatctac taatactata aaaaaacaag tgaataagac accagaacat cctctaatag
    18121 gacctatgga cttatatcaa tcccatatat actgtttaag caagatacta tcctagttga
    18181 cgctaacttc ctatcccact tattaatttt ttatttatag tgaatctgaa caaatcaatt
    18241 ggggaatcca agtcaatttc tagtactttt tgaacagttt cagcgtacta tcgtaaaatg
    18301 aaataaaaca tgcacaaatt gcttagggaa tttaaaccaa tttctaacaa tgtcttagaa
    18361 atcaaagtgt actatttcaa cttcaatata ctacacttca ttttctcctt aaattcagtc
    18421 tctttttgaa tcaaaaaatc ctctggtaag agccagagga taagaattta tttcattgtt
    18481 gggaagagca atacatcacg gatagttgtt gtatcagtga ggagcatgca gagacggtcg
    18541 ataccgattc ccaaaccacc tgttggtggc ataccgtatt caagagcttc aatgtagtca
    18601 tagtcgattc ctgtcgcttc atcatcacca agttctttgg ctttagcttg ggcttcaaaa
    18661 cggctaagtt ggtcgattgg gtcgttgagt tcagtaaagg cattaccgta ctccttagtc
    18721 atgataaaga gctcgaaacg gtcagtaaag cgttggtctt caggattttt cttagcgagt
    18781 ggagatacag ctactggatg tccatagaca aaggttggtt ggattaaagt ttcttcaaca
    18841 aactcttcaa agaaggcatt gatgatgtga ccaacctcag tgtagtgttt ctcaactgga
    18901 actttcttct cagcagcgat agctttagct tcttctaaag tcatgtcttg ccagaaatcg
    18961 acaccagtaa tttctctgat agcatccacc atatgaacac gcttaaatgg ttcgttaatc
    19021 ttgatttcag taccttggta gttgactggg ccatcgccct taactgattt agcagcgtgt
    19081 tggataatgc cttccgtcaa gtccatgatg tcttggaagt ctgcataagc ttggtaaact
    19141 tcgatagaag taaactcagg gttatgagta gcgtccattc cttcgttacg gaagatacgg
    19201 ccaatttcat agacacgttc cataccaccc acgataaggc gttttaagtg aagctcagtc
    19261 gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt gggtgataaa tggacgggca
    19321 gcagcaccac cggcttcatt atgaagaaca ggtgtttcca cttcaaggaa tcctttttgg
    19381 tcaaggtaac gacggatttc agagatgatt tttgaacgag tgacaaagcg ttcaaagctt
    19441 tcacgattag aaatcaagtc aaggtaacgt ttacggtaaa ttgtttcaac atctgtcaaa
    19501 ccatggaatt tctcaggaag aggacgaaga gccttagaca agtgtgtgat gtgggttgcc
    19561 ttgatagaga gttctcccat atccgtacgc atcacttcac cttcgacacc aaggaagtca
    19621 ccaaggtctg cttttttgaa gatttcgtag ttttcttcac cgacagcatc cttacgaacg
    19681 tagatctgaa tctggccttc gcggtcttga aggtgggcaa aaccaacttt tcctttacca
    19741 cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt ttttatcgtg taattgttct
    19801 ttatcgaggt tggcatattt atcttttaat tcttgtgaat ttgcagtacg ttcaaaacgt
    19861 tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca ttttttcacg gcgaacaatc
    19921 tgctggtcat ttagttcttc catatgttct gtagacatgg gatcctccta gttttactca
    19981 aaattgaata cgatgagtca ttttttgcga taccccattt tatcataaat aagcaagaaa
    20041 ttcacggata atctttaaaa actaaaaaga acctgacgct aaaatcactg gaaagaagtg
    20101 aaagtatctt ccgccccact agcgatatag ccaaatgctg ctttaggaat aacttgttgc
    20161 gccattggct ccaaatcata ggtattgatg aaatctacat gaccttctgc attgcttgtt
    20221 ttgtatgaca taaaatgtcc tccttaataa gtaagcgttt actttgtgta ttacaaaaat
    20281 atcttaactc tttttcaaaa cttttcaaat attttgtttg gaaatttcag aaattttatg
    20341 tctatggtaa aaaatcctta taacggcaat aaaaaataga tattatccaa agaagatttt
    20401 aagtgctaca ataactgtat tatttctaga tgggaggttc tatttttgga ttggtccatt
    20461 gttgaacaat atctaccact atatcaaaag gcattctttc tgaccttgca tattgcagtt
    20521 tggggaattt tgggatcctt tctgctcggt ttaatcgtta gtatcatccg acattatcga
    20581 atccctgttt tggcgcaagt agcgacagcc tacattgaat tgtcacgtaa tacgcccctt
    20641 ttgattcaac tcttctttct ctacttcggt cttccccgaa tcgggattgt cctatcttca
    20701 gaagtctgtg caacgcttgg ccttgtcttt ttaggaggct cctatatggc agaatctttc
    20761 cgaagtgggc tggaagccat cagtcaaacc cagcaggaga ttggcctcgc tattggtctg
    20821 acacctctac aggtctttcg ctatgtggtt cttccgcaag caacagcggt ggcactcccc
    20881 tcctttagtg ccaatgtcat tttccttatc aaggaaacct ctgttttctc agcagtggct
    20941 ttggccgacc tcatgtacgt cgccaaggat ttgattggtc tctactatga gacagacatt
    21001 gcgctagcta tgttggtagt tgcttatctg atcatgctgc tacccatctc actggtcttt
    21061 agctggatag aaaggaggac ccgccatgca ggattcggga atccaagtac tctttcaagg
    21121 aaataatctc ctgagaatct tacaggggtt gggcgttacg attgggatat ccatcctgtc
    21181 tgtcctctta tccatgatgt tcggaacagt catgggaatc atcatgacct cccattctag
    21241 aatcatacga tttttaacac gattgtatct ggaatttatc cgtatcatgc cccagctggt
    21301 gctactcttc atcgtttact ttggcttggc tcgaaacttt aatatcaata tctcaggtga
    21361 gacttcagct attatcattt ttaccctctg gggaacagct gaaatgggag acttggtacg
    21421 tggagctatc acttctctcc ctaaacatca gtttgaaagt ggataggcac tcgacttgac
    21481 taatgttcaa ctttactacc acatcatcat cccacaagtc ttaagaagac tgctaccgca
    21541 ggctatcaat cttgtcactc ggatgattaa aaccacttca ttagttgttt tgattggggt
    21601 tgtggaagtg accaaagttg gacaacaaat catcgatagc aatcgcctga ccatcccaac
    21661 tgcttcattt tggatttatg gaaccattct agtcttatat ttcgcagttt gctaccctat
    21721 ttccaaacta tccactcact tagaaaaaca ttggagaaac taaatgtctg aaactatctt
    21781 agaaatcaag gaactaaaaa aatccttcgg agacaatccc atcctccaag gactttctct
    21841 agaaatcaaa aaagggaagt tgttgtcatc ctagggccat ctggttgtgg gaaaagtacc
    21901 ctccttcgtt gcctcaacgg cttagaaagt attcaaggtg gagatatttt tctggatggt
    21961 cagtctatcg ttgaaaataa aaaagatttt cacctagttc gccaaaagat tggcatggtc
    22021 tttcaaagtt atgaactctt tccccatctg gatgtcttac aaaacctcat cctaggccct
    22081 atcaaagctc aaggaaggga caagaaagaa gtaacggaag aagctttgca attactagag
    22141 cgtgtcggtt tgctggataa acaacatagc tttgcccgtc aattatctgg tggacagaag
    22201 caacgtgttg caattgtccg tgccctccta atgcatccag aaatcatcct ttttgacgag
    22261 gtgactgctt cgctggatcc agaaatggtg cgtgaggtgc tggaacttat caatgatttg
    22321 gcccaagaag gccgtaccat gattttagta acccacgaaa tgcagtttgc ccaagccatt
    22381 gctgaccaga ttatcttcct cgaccaaggg aaaatcgctg aagaaggaac agctcaagcc
    22441 ttctttacca atccgcaaac caaacgagcc caggaatttt taaacgtctt tgactttagc
    22501 caattcggct catatctata aaggagattc ttatgaaact attcaaacca ctcttaactg
    22561 ttttagcact tgcctttgcc cttatcttta tcactgcttg tagctcaggt ggaaacgctg
    22621 gttcatcctc tggaaaaaca actgccaaag ctcgcactat cgatgaaatc aaaaaaaggc
    22681 ggtgaactgc gaatcgccgt gtttggagat aaaaaaccgt ttggctacgt tgacaatgat
    22741 ggttcttacc aaggctacga tattgaacta gggaaccaac tagctaaaga ccttggtgtc
    22801 aaggttaaat acatttcagt cgatgctgcc aaccgtgcgg aatacttgat ttcaaacaag
    22861 gtagatatta ctcttgctaa ctttacagta actgacgaac gtaagaaaca agttgatttt
    22921 gcccttccat atatgaaagt ttctctgggt gtcgtatcac ctaagactgg tctcattaca
    22981 gacgtcaaac aacttgaagg taaaacctta attgtcacaa aaggaacgac tgctgagact
    23041 tattttgaaa agaatcatcc agaaatcaaa ctccaaaaat acgaccaata cagtgactct
    23101 taccaagctc ttcttgacgg acgtggagat gccttttcaa ctgacaatac ggaagttcta
    23161 gcttgggcgc ttgaaaataa aggatttgaa gtaggaatta cttccctcgg tgatcccgat
    23221 accattgcgg cagcagttca aaaaggcaac caagaattgc tagacttcat caataaagat
    23281 attgaaaaat taggcaagga aaacttcttc cacaaggcct atgaaaaaac acttcaccca
    23341 acctacggtg acgctgctaa agcagatgac ctggttgttg aaggtggcca ttaactctta
    23401 aaagggactg gattttaagc tccaatccct ttttaagatt ttacctataa catcctgagt
    23461 ctatctaaga tgttcaatct gaacacagtg tacatacttt atcttctatt gcatatactt
    23521 tatcacataa gatacgaata tcctcttcac tatgactagc aatcaaaatt gttgtccctt
    23581 tttcactaga gagctttcta aacaatgttc tcatattttc tacacttgat ttatccaagg
    23641 cattcatagg ttcatctagt aaaagaatag agggattctc cataattgct tgagcaatcc
    23701 ctagcttttt cctcatacct agcgaataag ttttaacttt ctggtctttt tgctcatata
    23761 gaccaactat tttcagtgta tcactgattt cctgattacc aactactcct cgtatgcttg
    23821 ccaaatattg taaattctta aagccactat aataatttat aaaaccaggt tcttcaatca
    23881 aagctcccaa attagctgga atttttctct caggaacaat attttcccca ttgattaaca
    23941 cttctccata agacggacta tataaaccag ctattaattt aaacaataca cttttccctg
    24001 agccattcgc accagtaatt cctataattt ccccctgttt acaactaaaa ttaaggtttt
    24061 gaaaaacaca tgttt
//
LOCUS       DAVLTG010000028        23094 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLTG010000028 DAVLTG010000000
VERSION     DAVLTG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.028"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(90..3266)
                     /gene="carB"
                     /locus_tag="VYN12_001228"
     CDS             complement(90..3266)
                     /gene="carB"
                     /locus_tag="VYN12_001228"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1415617.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3578..4657)
                     /gene="carA"
                     /locus_tag="VYN12_001229"
     CDS             complement(3578..4657)
                     /gene="carA"
                     /locus_tag="VYN12_001229"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1415618.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMALDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4707..5630)
                     /locus_tag="VYN12_001230"
     CDS             complement(4707..5630)
                     /locus_tag="VYN12_001230"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1415619.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5649..6170)
                     /gene="pyrR"
                     /locus_tag="VYN12_001231"
     CDS             complement(5649..6170)
                     /gene="pyrR"
                     /locus_tag="VYN12_001231"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1415620.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6381..7010)
                     /gene="nth"
                     /locus_tag="VYN12_001232"
     CDS             complement(6381..7010)
                     /gene="nth"
                     /locus_tag="VYN12_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1415621.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(7010..7552)
                     /locus_tag="VYN12_001233"
     CDS             complement(7010..7552)
                     /locus_tag="VYN12_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1415622.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7721..7861
                     /locus_tag="VYN12_001234"
     CDS             7721..7861
                     /locus_tag="VYN12_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV1415623.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            8276..9835
                     /locus_tag="VYN12_001235"
     CDS             8276..9835
                     /locus_tag="VYN12_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1415624.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9984..10883)
                     /gene="htpX"
                     /locus_tag="VYN12_001236"
     CDS             complement(9984..10883)
                     /gene="htpX"
                     /locus_tag="VYN12_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1415625.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSTLYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(10885..11445)
                     /locus_tag="VYN12_001237"
     CDS             complement(10885..11445)
                     /locus_tag="VYN12_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1415626.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11539..12252
                     /gene="rsmG"
                     /locus_tag="VYN12_001238"
     CDS             11539..12252
                     /gene="rsmG"
                     /locus_tag="VYN12_001238"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1415627.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12555..13838
                     /locus_tag="VYN12_001239"
     CDS             12555..13838
                     /locus_tag="VYN12_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1415628.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFIPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14033..15604)
                     /gene="ffh"
                     /locus_tag="VYN12_001240"
     CDS             complement(14033..15604)
                     /gene="ffh"
                     /locus_tag="VYN12_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1415629.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15616..15948)
                     /locus_tag="VYN12_001241"
     CDS             complement(15616..15948)
                     /locus_tag="VYN12_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1415630.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(16039..16416)
                     /locus_tag="VYN12_001242"
     CDS             complement(16039..16416)
                     /locus_tag="VYN12_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1415631.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKRDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYILTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16488..17792
                     /locus_tag="VYN12_001243"
     CDS             16488..17792
                     /locus_tag="VYN12_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1415632.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            17805..18611
                     /gene="yidA"
                     /locus_tag="VYN12_001244"
     CDS             17805..18611
                     /gene="yidA"
                     /locus_tag="VYN12_001244"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1415633.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(18667..18738)
                     /locus_tag="VYN12_001245"
     tRNA            complement(18667..18738)
                     /locus_tag="VYN12_001245"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18703..18705),aa:Arg,seq:cct)
     gene            complement(18781..19128)
                     /gene="rplS"
                     /locus_tag="VYN12_001246"
     CDS             complement(18781..19128)
                     /gene="rplS"
                     /locus_tag="VYN12_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1415634.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19247..19576)
                     /gene="crcB"
                     /locus_tag="VYN12_001247"
     CDS             complement(19247..19576)
                     /gene="crcB"
                     /locus_tag="VYN12_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1415635.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(19570..19944)
                     /gene="crcB"
                     /locus_tag="VYN12_001248"
     CDS             complement(19570..19944)
                     /gene="crcB"
                     /locus_tag="VYN12_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1415636.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19941..20207)
                     /locus_tag="VYN12_001249"
     CDS             complement(19941..20207)
                     /locus_tag="VYN12_001249"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1415637.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20323..20766)
                     /locus_tag="VYN12_001250"
     CDS             complement(20323..20766)
                     /locus_tag="VYN12_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1415638.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            20870..21805
                     /locus_tag="VYN12_001251"
     CDS             20870..21805
                     /locus_tag="VYN12_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1415639.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21859..22143
                     /locus_tag="VYN12_001252"
     CDS             21859..22143
                     /locus_tag="VYN12_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1415640.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22200..22418)
                     /locus_tag="VYN12_001253"
     CDS             complement(22200..22418)
                     /locus_tag="VYN12_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415641.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(22415..22989)
                     /locus_tag="VYN12_001254"
                     /pseudo
     CDS             complement(22415..22989)
                     /locus_tag="VYN12_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6800 a         5160 c         4411 g         6723 t
ORIGIN      
        1 caattagaaa attcaaatta atttatagaa atattttagt attcctgtgt actgttctaa
       61 attcagtctg ctatatctta tttttctatt taaatcgctt ctgtaacaaa gctacgactt
      121 tcaagtacct taagcatggc attagctgta tctagcgctg tgaagagggg caccccgtgt
      181 tcaatggctg aacgacgaat ttgctcacca tcttcgtcag cagttcgttt tgttcctact
      241 gtgttaatga tagcttgaat tcttcctttg cgtacaaaac ttgggatatc cttatcgtca
      301 tcaccaatct taccaacagg ttgggcttgc aagccatgac tagcaaagaa ggctgctgtc
      361 ccttctgtcg caaggattcc ataaccaatg ttttggaaac gacgagccaa gttcaaggct
      421 tcttctttgg catcatcagc gatggtaaag acgacattac caaaagttgg caagtgtaga
      481 taagaagctt caaaggcttt atagagagct ttttccaaag tagcatcaga acccataact
      541 tcacctgttg acttcatttc aggaccgagc aagctgtcta ccttagctag tttggtaaag
      601 gagaagacag gtgccttgat atgaacacgg gtgctttcag ggtaaagtcc attttggtag
      661 ccaagttctg ataaactttg accaagaatg agcttggtcg ctacttgagc cataggaata
      721 ttggttacct tagataggaa tggaacagta cggctggcac gtggattgac ctcaataacg
      781 tagacttttt catccttgat aacaaactgg atgttcatca ttccaaggca gtgaagaccg
      841 attgctaagc gtttggtgta gtctgcgatg gtctcctgaa ccttttgcga caaggtttgt
      901 ggtgggtaaa cagccattga gtcacctgag tggacaccag cacgttcgat atgctccatg
      961 ataccaggaa tgagcacatc tttaccatct gaaatggcat caacttcgca ctcttgccca
     1021 acgatataag agtcgacaag aactgggtga tctggactag ccttaacagc agttcgcatg
     1081 taagaacgaa ggtcttcttc gttttcaacg atttccatgg cacgtccacc aagtacataa
     1141 gatgggcgga caagaactgg gaagccaatc ttacgagctg caagagctgc ttcttcttca
     1201 ttggtagccg tttgtcctgg tggctgtgga atatccaatt ctttgagagc ttgctcgaag
     1261 aggtcacggt cttcggcacg gtctaggtca gcaacctgtg taccaaggat ggtcacacct
     1321 gcttttgcca atggctccgc aaggttgatg gctgtttgac caccaaactg aacgataact
     1381 ccctttggtt gttccaagtc aatgacgttc ataacatctt cgaatgtcaa tggctcaaag
     1441 taaagcttat ctgatacaga gaagtctgtt gaaacggtct ctgggtttga gttcatgatg
     1501 atagcttcat aaccagctgc ctggatagcc ttaacagagt gaacggttgc gtagtcaaac
     1561 tcaacccctt gaccgatacg gattggacct gaacctagga caagtacaga ttctttatca
     1621 gatctgatag attcattttc ccaaccatag gttgaataga aatatggcgt ttcagagtcg
     1681 aactctgccg cacaagtatc taccatctta taaactggaa caatcttgtt ttccaagcga
     1741 agttggcgaa cttgatcatc agtcgttccc cagagttcag caatcttacg gtctgagaaa
     1801 ccattaagtt tggctgtttt caaaacttct agatcttgtg gatgagcacc caattcttgc
     1861 tcaatttcaa agatatgcaa gagtttatca agatagaaga tatcaatttt tgtaagctct
     1921 gcaatttctt caggtgtgta gccacgacga atggcttctg atacgtagaa gagacggtca
     1981 tcttgggctt tgacaacctt ttcaatcaag gcatcatcag aaactgctgc aagttcaggt
     2041 atttcattgt ggtgcacccc aatttcaagg gagcggcagg ccttgagaag agattcctcg
     2101 atgttacgac cgattgccat gacttctcca gtcgccttca tttgtgtacc gagacggcgt
     2161 tcaccctttt caaacttgtc aaatgggaaa cgtggaatct tagcaactac gtagtcaagg
     2221 gctggttcaa acatggcata ggttgaacct gtaactgggt ttataacctc atccaaggtc
     2281 aaacctactg caatcttggc agccaactta gcaatcggat atcctgtcgc tttagaagca
     2341 agggctgacg aacgtgatac acgagggttt acttcgataa cataatactt gaagctgtta
     2401 ggatcaagag ctagctgaac attacatcca ccttcaatct tgagggcgcg aataatgctc
     2461 aagctcgcat cacgaagcat ttggttttca tagtctgaca tggtttgcgc aggggcaaat
     2521 acaatggaat cccctgtgtg aatcccaact gggtcaaagt tttccatgtt acaaacaacc
     2581 aaggcattgt cagctgagtc acgcatcact tcgtattcaa tttccttaaa accggcaatc
     2641 gaacgctcaa tcaaacattg ggtaacaggt gacaatttca aaccattttc agtgatttca
     2701 cgcaattctt tttcgttggc acacatacca ccaccagtac caccaagggt aaaggctgga
     2761 cgaacgatga ctgggtagcc aattgtcgct gcaaaggcaa ctgcttcttc tactgtgtta
     2821 acaatttcag attctggaat gggttgctca agctcttcca tcaattgttt aaagaggtca
     2881 cggtcctccg cttggtcaat ggcagataat ttggtaccca gaagttcaac gccaagctcg
     2941 tctaggatac catttttaga taattccatg gccatgttga gacctgtctg accaccgagt
     3001 gttggtagca aggcatctgg acgttcctta cgaagaatac gtgtcacaaa ctcaagtgta
     3061 atcggttcaa tgtaaacctt gtcagcaatt tccttgtccg tcatgatggt tgcaggattt
     3121 gagttaacca aaacaacctc ataaccttcc tctttcaacg acaagcaagc ctgggtccca
     3181 gcgtagtcaa actcagcagc ctgaccaata ataatcggac cagaaccaat caccataatt
     3241 ttttgaatat cagtacgttt aggcatagtt tatgatacaa agcccgtaaa gaacacagtg
     3301 aaaataggaa actcggcgca gacgccttca gcgtcaagac gatgtttatc tttttcacac
     3361 agttcttagg gcgtgttcac ttccgcgaac aatgtatctt ctcctttcta ttcgtcgcct
     3421 ctcagggcga cattaaataa gatacaaagg acgaatagaa agcgattgaa ttttaagaaa
     3481 tcaaggaagg attgacaatc caagttggtt tctctaaatt ctgagctttc cgtccgtgtt
     3541 cagttacata aattctccga cgagctttta ctcgttctta gtttgattgt ttaaaaactt
     3601 ccatcatctc gataaactcg tcaaataggt agctagcgtc gtgtggccca ggagctgcat
     3661 ctgggtggta ttgaacagag aaagcaggtt ggtatctgtg gcgcacacct tccactgact
     3721 tgtcattgat ttcttcgtgg gtaataatca agtgctctgg caaatcctcg cggctgactg
     3781 cataaccatg gttctggctg gtgaagtcta ctcgtcctgt tgcgatttca cgtaccgcat
     3841 ggttgaatcc acgatggcca aacttcatct tataggtctt agccccgttt gccattgcaa
     3901 agagttggtg tcccatacaa ataccaaaga ttggaatttt tccttgtaca ccgcgaatca
     3961 tgtcgagtgc ttgtggaacg tcttctgggt tacctggacc atttgacaac ataactccat
     4021 caggattgag atggagaatt tcttcagccg ttgtcgaata aggaacaact gtcacgttac
     4081 agttgcgttt agaaagttca cgtaggattg agtgcttgag accaaagtcc actagcacca
     4141 cgctcaaacc aactcctgga gctggataag acgttttagt agaaacctgt ttgatattgt
     4201 ctgtcggtaa aactgttgct tggagctggt ccgtcacatg gtccatactg tccccaacat
     4261 gggtcaaggt tgcacgcata gtaccatgct tacggataat cttggtaaga gcacgcgtat
     4321 caattcctga aatccctgga attttcttgg ctttcaaaaa ttcatccaag gccatttggt
     4381 tgcgccagtt gctagctcta cgcgcttctt caaaaacaac gactccctta caagttggaa
     4441 taatggattc ataatcatca cgattaatac cataatttcc taccaaagga taagtaaagg
     4501 tcaagatttg tccattataa gactggtctg taatggattc ttggtagccg gtcatccctg
     4561 tattaaagac gatttcgcct gttacatcaa tatctgctcc gaaggccttg ccttcaaaaa
     4621 ctgtgccatc ttctaatact agaattcttt ttgtcatatt ttcacctctc gtggacgctc
     4681 actggcgtct tttaacgtct tgtgttttag ttggcgtttc tactcgctag tacggattct
     4741 aagattgcca ttcgaacaaa gacaccattg gtcatttgtt ggacaatccg tgattttggt
     4801 gcttcaacca agtggtctgc tatttctaca tcacgattga ttggagctgg gtgcatgagg
     4861 attgctgttt ctttcaaacg atcgtaacgt tcttgagtca agccatgttg ggcatggtag
     4921 tcttcttttg aaaatacagc tccactatca tggcgttcgt gttgcacacg gagaaacatc
     4981 atgacatcaa cctgatcaat gatttcatca atggttacaa actgtccata gtctgcaaac
     5041 tcttgacttc tccattcctc aggtccagcg aaaaagagtt cagctcccaa gcgtttcaaa
     5101 atctgcatat tggatttggc aacgcgtgag tgatccaagt cacctgcaat agcaacttta
     5161 agaccctcaa agtggccaaa ttcctcataa atggtcatca aatcaagcaa gctctggcta
     5221 gggtgttggc ccgaaccatc tccaccattg atgatggaag tcgtaatcgt tggactagca
     5281 atcaattctc tatagtagtc gacctctgga tggcgaatca cacagacatc cactcctaaa
     5341 gcagacagag tcaaaatggt gtcataaagt gtctcaccct tattaaccga actagtcttc
     5401 acatcaaagt caagtcgttc caatccaagt ttaatctctg cgacttcaaa ggacttatgt
     5461 gtccgtgtag aatcctcaaa gaagagattg gaaacaatcg gatggtcttc atagggaagc
     5521 tgggctccat ttttaaactc aattcctcgc ttgatcaatt tcattacttg atcgacagtg
     5581 aggtcttcca tggacaccac atggttcaat gcttgttgat tttctgacat ggctactcct
     5641 ttaactttct aagcttcttc agtaatcaga actctgtctt ggtcatcaag ttctgtcatc
     5701 tctacgatga tttcttcaga acgactggtt gggatatttt ttccaacgta atctggacgg
     5761 attggcaatt ctctatgtcc acgatcgact agaactgcta aactcacacg cgcaggacga
     5821 ccatgaccga caatattatc aatagcagca cggatggtac gacctgtata gagcacatca
     5881 tccaccaaga taacttcgcg gtctgtcaca tcgacagaaa ccaaagaagt atcttctcca
     5941 cttttaacat catcacggaa aggtttagta tccaattcca caacaggaac tgaaagattt
     6001 tctaactgct tcaaacgttc ttggattcgg tgggcaataa agacaccacg agttttaata
     6061 ccagccaaga cgatcttatt caaatctttg ttgcgttcga taatctcata agtaatacgc
     6121 gtaatcgctc gtttgacggt caattcgtct acaacttctt ttgttttcat gacaaacctc
     6181 caaaaagaaa agtctcctta aacaaggaga cttgaaattt atagccaagc gagccctact
     6241 gcacacagtg tagacttcac ccttctactt tatcgcgctc cttgcctgcc tcacgggaca
     6301 ggtttaaagg aatatttagt tatcatttac tatagcacaa agcatgctta aaatcaagca
     6361 aaaagtttca atgtagcatc ttacaaattg ctaaaatcat ataattgtgg gtactggtca
     6421 cactctggat tttttggatg gcaaatggct cttccaaaat aaatcatggc ctgatgggca
     6481 gctaaccact gctcaggcgg caagatatcc atgacccgct tttccacctc aagtggcgtc
     6541 gctgattttt tgacaatatc gtggtgtttg caaatacgct ccacatgagt atccactgca
     6601 aaggctggaa tcccaaatcc tacactcatg acaacattgg ctgtcttgcg accaacacct
     6661 gccaaactct ccaattcttc acgtgtctga gggacttgac catcaaaatc gtctagtaac
     6721 tgttgggcac attttttaag gaatttagct ttattccgat acaatcccaa gcgagaaata
     6781 tgtgaagcaa tctcactctc tgtcgctaca gacatagctt ggggtgttgg aaaggcaaca
     6841 aagagacctg gtgtggcctt atttaccgct gcatctgtcg tctgggctga taacatgacc
     6901 gcaaccagga gttcaaaatg attggtaaaa tcaagactag gcttggcatc tgggaagagg
     6961 gcaatgattt cttctagcac ctttcgtgct cgtttttttg acaagaccat tattcatctc
     7021 cgtcaaatag tccttgtaag ccagcaaaag gactgttttc ttctttcttt actgcttgtt
     7081 gagcttggta ttcttcctct gtcatgattt gccagtcatt tcctgagaca aatccttgac
     7141 cagcttcttc ttcagccgtc aagaccttga taggaatgtt tagcaggata ttgtctgata
     7201 cactctcagc aaggtcaagc gccccatttt cgatgggcaa gaccaagtca tcatctaaaa
     7261 cttcttgatc tagctggtta gttgcgcctt ccatgaaaac ttccgtgact ggataagatt
     7321 caactaactc aactggctcc atactgcgac tcgaagcaag aacaatggta taagatagtt
     7381 gataatctaa gaaatacata cggtcttcat attgtacttt cccaactgca aggatatctt
     7441 ttacatctaa aatttcttga ttacgtgcac gcaggtcatc aactaaatct aacgtttgtt
     7501 caaagttcaa accttcagac tgcttacgaa tttcttgaat atttaatttc atacttcctc
     7561 cataaagatt tactctcttg attataccat gaaaaggcta caaatcagca caccaaactt
     7621 tgtaattaaa attcaaattt taacatattt actatgatag ttttattttt tagtgctata
     7681 ctatagggaa agagtacatc agatcaagga ggatgctcac atggaagaca agaaactcat
     7741 tcaactccta tccaagttaa ataaaagcta ccaaaactgt aaacaggtta cggcagatga
     7801 tattcgacta caagagctgc taaacactac tatgcaagag ctcaaaaaac agaaaagttg
     7861 aacaacagta tcttaattaa tcttgagaaa ttttaccaac ccaccagtcc tctgattgga
     7921 ctgggtagcc taaaactaaa caatcaagca cgcactgctt ggcgaaacta tgataaaatc
     7981 cattacgagt atgtcaaaca cgtactaagt ctctatggac ctgtttttgg attttagagc
     8041 atagaatttc cagttttctg ttgacaaaat ttccttaaag gtataatata aagatactaa
     8101 tactcggagg taagggagac atgaacaact aagtctatca aataaagaac ctttatttag
     8161 tagatcttgt ttttgtctct ttttgtgtgc tcttttatgc tctttttctg gcatgttaat
     8221 agagtttttt tgacatagac tttgggctct actaggtaaa gtagagcttt ttgttatgca
     8281 ctatcgacat tctagaaagg gcaatagtat gataaaaatc aatcacctga ccatcacaca
     8341 aaacaaagat ttacgagacc ttgtctctga cctaagcatg accatacaag acggggaaaa
     8401 ggtagctatt attggcgaag aaggaaatgg taaatcaacc ttacttaaaa ctttaatggg
     8461 ggaagatttg tctgatttca ctatcaaggg agacatccaa tctgactatc agtcactggc
     8521 ctacattcct caaaaacttc ccgaggagct gaaaaagaaa actttacacg actacttctt
     8581 tttagattct attgatttag actacagtat cctctatcgt ttggcggagg aattgcattt
     8641 tgatagcaat cgtttcgcaa gtgaccaaga gattggcaat ctatcagggg gagaagcttt
     8701 gaaaattcag cttatccatg agttagccaa accctttgag attctatttt tagatgaacc
     8761 ttcaaatgac ctagaccttg agacagttga ttggctaaaa ggccagattc aaaagaccag
     8821 gcaaaccgtt attttcattt cccatgatga agactttctt tctgaaacgg cagacactat
     8881 tgttcacttg cgactggtca aacaccgtaa agaagcggaa acgctagtag agcatttaga
     8941 ctatgatagc tatagtgagc agagaaaggc taattttgcc aaacaaagtc agcaagctgc
     9001 taacaaccaa agagcctacg ataaaaccat ggaaaaacat cggagagtta agcaaaatgt
     9061 agaaactgcg cttcgagcta ccaaagatag tactgccggt cgcctattgg ctaaaaagat
     9121 gaaaactgtc ctctcacaag aaaaacgcta cgaaaaggca gctcagtcca tgactcaaaa
     9181 accacttgaa gaggaacaaa tccaactttt cttttcagac atccaaccat taccagcttc
     9241 taaagtctta gtccaactgg aaaaagaaaa tttgtccatt gacgaccgag ttttggttca
     9301 aaaactacaa ctaactgtcc gtggccaaga aaaaatcggt attatcgggc caaatggtgt
     9361 tgggaaatca actctgttag ccaagttaca gagacttctg aatgataaaa gagagatttc
     9421 acttggtttt atgccacaag attaccacaa aaaactgcaa ttggatttat ccccaatagc
     9481 ctatctcagt aaaactgggg aaaaagagga actacagaaa atccaatctc acctagctag
     9541 tctcaatttc agttatccag aaatgcagca tcaaattcgc tccttatctg gcggacaaca
     9601 gggaaaactc ctgcttttgg atttagtcct gcgcaaacca aactttctcc tgctggatga
     9661 acccacacga aacttttctc ccacttctca accccaaatc agaaaactct ttgccactta
     9721 tcctggcggt ctcatcactg tttcgcatga ccgtcgtttc ttaaaagaag tctgctcgat
     9781 catctatcgc atgacagaac acggtttgaa gctagttaat ttagaagatt tataaatttg
     9841 caacatagca gataggtggg gcaaaaacac aattttagga gaaaaagaag taaatcttcc
     9901 catagtaaaa cgcataatat caagttttca cacctgatat tatgcgtttt tcagatttta
     9961 aagacttttt tccagccttc attttacata tgttttaaac gttcaatccg ttctgagata
    10021 ggtgggtggg tataaaagag tttttggaac cccccacctt tcttgggatc attgatataa
    10081 agggtactgc tagcatcatc gacgtggcga ctcataggtt tgctattgtc caacttatct
    10141 agggcattaa tcattccctg gggattgcga gtcagctcga cactagatgc atctgccaga
    10201 aattccctct gacgagaaat agcgagctga accaaggttg cagcgagagg tgccagtaca
    10261 atagctagta gggaaaccac tagcataatg atttcaagac catttccatc tcggtcatca
    10321 tcacttcgtc tgcgacctgc tccaccccac cacatcatac gacctgccat actagaaagc
    10381 atggtgatag cactagcaag ggcaactgca atagtcgaaa tacggatatc ataattacga
    10441 atatgactga cttcatgtcc cataacagct tctagttctt cacgattcat gatagctagt
    10501 agacctgaag tcgcagcaac agccgcattt tgaggattag aacctgtcgc aaaggcattt
    10561 aaggctggat catcaatgat gaaaacacgg ggcataggaa tctgagcgac cagagccata
    10621 tcttccacta catggtagag gtctggtgcc gtttgctcat ccacctcacg cgctccattc
    10681 atggacatga caatctctgt cgattgaaaa atcatagaca aagcgtagat aaagccgata
    10741 atcagtgcga taaccaaacc accaagtcca gatcttataa agagataacc aaccgcataa
    10801 ccaacaagag ctaagagtag gaaaaatacc agcaacaaaa tccaggtttt tcgtttattg
    10861 cttgcaattt gatcaaacaa catcttagtc acctaaaccg ctaaaatcaa ctttaggaac
    10921 cgacttttcc tcttcaggtg tttgaaggaa atctgccgct ttaaatccaa acattccagc
    10981 gataatattg ctcgggaaag tttctaattt tacattgtag ttgctgacaa cactgttata
    11041 gagttgacga gagtaagaaa ttttattttc tgtgtttgtc aactcctctt gcaatttaac
    11101 aaagttagca ctagctttca aatctggata gctttctgca actgcaaaaa tacctgaaac
    11161 ttgacgagtg agggcatcac tggctttcat agcttctgct ggtgaagtcg ctgccgccac
    11221 ttggttacgt agttctgcca ccttttcaag ggtagaacct tcatatttgg cataaccttt
    11281 tacagtctca atcaagtttg gcaagaggtc atttcgacgt ttcaactgaa catcaatctg
    11341 actccaagcc tccttggttt gcatacgatt tttaaccaaa ccgttatagc taacaatcac
    11401 aaaaataaca ataagagcga taactccaag aataatccaa gtcatgatat aagtcctttc
    11461 tacttttaga ttagtaccag tatatcaaat ttttaatgat tgtggtaaaa taagatgata
    11521 ctaaagaagg aaataactat gaaaccagaa acattttaca acttgcttgc cgagcagaat
    11581 cttccacttt cggaccagca aaaagaacaa tttgaacgtt attttgagct cttggtcgag
    11641 tggaatgaga agattaattt gacggcgatt acggacaagg aagaagttta tctcaaacat
    11701 ttttacgatt cgattgcacc cattcttcaa ggtttgattc ccaatgaaac tatcaaactt
    11761 cttgatatcg gggctggggc aggatttcct agtctaccaa tgaaaattct ctatccggag
    11821 ttagatgtga ccattattga ttcactcaat aagcgcatca acttcctaca actcttggct
    11881 caagaactgg atttgaacgg agttcatttc taccacggac gtgccgaaga ttttgcccaa
    11941 gacaagaact tccgtgctca atatgatttt gtaacagctc gtgcggttgc ccgtatgcag
    12001 gtcctatctg aattgactat tccctacctt aaggttggtg gaaaactatt ggcactcaag
    12061 gccagcaatg cgcctgagga gttgttagaa gctaagaatg ccctcaatct cctttttagt
    12121 aaggtcgaag acaatctcag ctacgcccta ccaaatagag atccgcgtta catcacagtg
    12181 gtagaaaaga aaaaagaaac accaaataaa tatccacgta aggctggtat gccaaataaa
    12241 cgcccgcttt aaatttttaa gtaaaaaaat atttacaaaa tcaacctcgc tcttttattt
    12301 ctaggctcgg gaaaaaatga tttacaaaat cagcctcgct cttttatttc taggctcggg
    12361 aaaaaatgat ttacaaaatc atttttttct gctatactat cctaagcaaa ggtttttaat
    12421 gtcatcccgt gaggtgacga agacgcaaaa atatttgaaa ctctttaaag tctagatttt
    12481 agagaagtct tactctgagg gcctattgct gtaaaataat gggctctttt ctgatgccca
    12541 aaagtgaggt ttatatgaaa caagaatcaa ctgttgattt gttattagac gttgaccaac
    12601 gtccttcggc tggaaaagga attctcctta gcttccaaca cgttttcgcc atgtttggtg
    12661 cgaccatctt ggtaccattg attttgggaa tgcctgtatc tgttgccctt tttgcttcag
    12721 gtgttggaac actcatctac atgattgcta ctggttttaa agttccagtt tatctaggtt
    12781 cttcatttgc ctttatcaca gctatgtcac tggctatgaa agaaatgggg ggtgatgtat
    12841 ctgctgccca aacaggggtt atcttgactg gtttggtcta tgtccttgtt gctaccagca
    12901 tccgatttgt aggaacaaaa tggattgata aactcttgcc accaatcatt atcggtccta
    12961 tgatcatcgt tatcggtctt ggacttgcag gttcagctgt taccaatgca ggtcttgtag
    13021 cagacggaaa ttggaaaaat gctctggtag ccgttgttac tttcctaatt gctgccttta
    13081 tcaatacaaa aggaaaaggc ttcctacgaa tcattccatt cctctttgcc attatcggtg
    13141 gttacctttt cgcactaact cttggcttgg ttgactttat accagttctt aaagccaact
    13201 ggttcgaaat tcctggtttc tacttgccat ttagcacagg tggtgccttt aaagagtaca
    13261 atctttactt tggtccagaa gccatcgcta tcttgccaat cgctatcgta acaatttctg
    13321 aacatatcgg agaccatact gttttgggtc aaatctgtgg tcgtcaattc ttaaaagaac
    13381 caggtcttca ccgtactctt cttggtgacg gtatcgcaac ttctgtttct gccttccttg
    13441 gtggaccagc caatacaact tacggagaaa atacaggggt tatcggtatg actcgtatcg
    13501 cttctgtctc agttatccgt aacgctgcct tcatcgcgat tgccctcagc ttccttggta
    13561 aattcactgc cttgatttca actattccaa acgctgtact tggtggtatg tcaatccttc
    13621 tctatggggt tatcgccagc aatggtttga aagtcttgat taaagaacgt gttgatttcg
    13681 ctcaaatgcg aaacctcatc atcgcaagtg ctatgttggt tcttggactt ggaggagcta
    13741 tccttaaact tggtccagtt acactttcag gtactgccct ttcagccatg acaggaatca
    13801 tcttgaactt gatcttgcca tacgaaaata aagactaaga gtctaaatac acctaatcca
    13861 ctcagacagc tgagtggatt tttcgtatac cataataaaa gtgtcttaac aaaattatta
    13921 aaatcaaaaa acgtataata tcagatattc taaaaccttg atactgtacg ttttatcata
    13981 gaaattttta ctttattttc tcatcaaatg agatttgcat caatctcttg tcttacttgc
    14041 gtttcttctt cgctttcttc attttgttag ccatacgttt catggactgt ttcatggcaa
    14101 attcaccaat tttacctttc aaaccgccac caaacatctg gctcatatct ggcattcctg
    14161 ctcctccgag agctgataag tcaggcatac cgccttgtcc catcattcct tcaagggcag
    14221 acatatccat tcctcccata tttggcatat ttttaggaag gttatttgga ttaatcccca
    14281 tttgcttcat cattttattc atatccccag acataacacc ctgcatgagc tgtttagcct
    14341 ggttaaagtc cttgatgaat ttattgactt cgacgaatgt atttccagaa ccagcagcaa
    14401 tacgacggcg acggcttgga tttaacaaat ctgggttttc acgttcttca ggtgtcatcg
    14461 aagacacaat cgcacgttta cgagcaatct ggcgttcatc caccttcatg ttttgaaggg
    14521 ctggattgtt ggccatacct ggaatcatct tgagcaagtc ttccatcggc cccatatttt
    14581 gcacctgatc taattgatcg atgaaatcat taaaatcaaa ggtgttttcg cgcatcttct
    14641 cagccatttc aagggctttt tgttcatcgt attcctgaga agctttctca atcaaagtga
    14701 gcatatcccc cataccaagg atacggctag acatgcggtc tgggtggaag gtttcaatgt
    14761 ccgtaatctt ttcacctgta ccagtgaact tgattggttt tccagtaatg tgacgaacag
    14821 acagagcagc accaccacga gtatcgccat caatcttggt aaggatgacc ccagtcactt
    14881 ccaactgagc attaaactca cgcgcaacat tggctgcttc ctgaccaatc atagcatcaa
    14941 cgacaagcaa gatttcattt ggttgagcca atgctttcac atcacgaagc tcattcatga
    15001 ggagctcatc aatctgcaaa cgacccgcag tatcaatcaa gacatagtcg ttatgattag
    15061 tttgggcttg ctccaaacct tgacgtacaa tctcaacagc tggtacttct gttccaagtg
    15121 caaagacagg cacatcaatc tgttgtccca aggtcttaag ctggtcaatg gcagctggac
    15181 gataaatatc cgccgcaatc atcaaaggac gagcattttc ttctttcttg agtttgttgg
    15241 ccaatttacc agcaaaggtt gttttaccag ccccttgtaa accaaccatc atgatgatgg
    15301 ttggaatctt aggtgacttg ataatttctg ccgtatcaga acctaaaacg gctgtcagtt
    15361 cctcatcaac gattttaata atctgttgcg caggattaag tgtatcaatg acctcatgcc
    15421 cgactgcacg ctcacgaact ttcttgataa agtcctttac aacaggcaag gcaacgtcgg
    15481 cctcgagcaa ggccaagcga atttctttgg ttgcctcttg gacatcagat tcagagattt
    15541 ttcctttttt acgtagattt ttaaagacgt tctgcaaacg ttctgttaaa ctttcaaatg
    15601 ccatttttct tcctcttatt ctctattatc aatgcttgtt aaaatttcta tctgctcctg
    15661 cagaaagtca tccttgggat agcgctccaa aatctgatca aaaatctgac tgcggacaat
    15721 atagtccgag tacatgtgca atttcatctc ataatcttcc agaatctttt ctgttcgctt
    15781 gatattgtca tagacagcct gacgactgac accgaactcc tcggcaattt cagcaaggct
    15841 gtaatcatca gcgtagtaga gctcgatata attcatttgc ttatctgtca aaagcgccgc
    15901 ataaaattca aagagcgcat tcatacgatt ggttttttcg atttccataa cttttattat
    15961 accaaaaatt agcctaatct accacactag gaagccgatc caagaagata gatagctaaa
    16021 tttgaaaaag acatgagcct agccccaagt aatttccaat tgatagctgg caaagggatg
    16081 tccctcttga ttttgtagtt gataatctag ttcaatcttt tgcctatcaa cttgataatg
    16141 gctcgtttgg atggtaaact cctgcatgcc cataggtgta agaatatagg ctaaactatc
    16201 gctatccttt agaaagcgca taatggtctt gggattagaa aatcggctca tcacaagttc
    16261 ttgaccatga aatttaatca ctactttttc cttttcctca ttatagaaaa gcaggtagct
    16321 ataatctctt ttttcatgca cttccacatc ataaagctgg tcaatcactt ccaactgctc
    16381 atcaaactga atcgtatttc gcatccgaat cttcacatca ggccctcttt cttgtctctt
    16441 gtcctactat tttaccaaaa agagcaggat tttgctataa tggtcatatg aacgaaaaag
    16501 tattccgtga cccagttcac aactacatcc atgtcaataa tcaaatcatc tatgacttga
    16561 ttaatacaaa agaatttcag cgtttgcgcc ggatcaaaca actgggaact tccagttata
    16621 ccttccacgg tggagaacac agtcgcttct ctcactgtct aggagtctat gaaattgcac
    16681 gacgcatcac agagattttc gaagaaaaat atcctgagga atggaatcct gccgagtctc
    16741 tcttgaccat gatcgctgct ctcctacatg accttgggca tggcgcctac tcccatactt
    16801 ttgaacatct ctttgataca gaccatgaag ctattactca ggagattatt caaagtcctg
    16861 agacagagat tcaccaagtc ttgctacaag tagcgcccga ttttccagag aaagttgcca
    16921 gtgtcataga ccatacctat cctaacaagc aggtcgtaca actcatttct agtcagattg
    16981 acgcagatcg catggactat ctcttgcgtg actcctattt tacaggagca tcctatgggg
    17041 aatttgacct gactcgaatc ctccgagtca ttcgtcctat cgaaaatggt atcgcctttc
    17101 agcgcaatgg catgcacgcc atcgaagact atgtcctcag tcgctaccag atgtatatgc
    17161 aggtctattt ccacccagca acacgcgcta tggaagttct cctacagaat cttctcaagc
    17221 gcgctaagga actctaccct aaggacaaag acttctttgc acgaacttcc ccacacctcc
    17281 tgcctttctt tgaaaaaaat gtgaccttgt ctgactatct ggctctagat gatggtgtga
    17341 tgaataccta cttccagctc tggatgacca gtcctgacaa aattctcgca gatttatcgc
    17401 aacgctttgt caaccgcaag gtctttaaat ccattacctt ttcacaagaa gatcaagacc
    17461 aactcgctag catgagaaaa ttggttgagg acattggctt tgatcccgac tactatactg
    17521 ccattcataa gaactttgac ctcccttatg atatctatcg tcccgaatct gaaaatccac
    17581 ggacacagat tgagatttta caaaagaatg gagaactggc cgaactctct agcctgtctc
    17641 ctatcgtcca atcccttgct ggtagtcgtc acggagataa tcgtttctat tttccgaaag
    17701 aaatgttaga tcaaaacagt atctttgcta gcattaccca gcaattttta tacttgattg
    17761 agaacgatca ttttacccca aataaaaact agaagaggaa atttatgagt attaaactaa
    17821 ttgccgttga tatcgacgga acccttgtca acagccaaaa ggaaatcact cctgaagttt
    17881 tttctgccat ccaagatgcc aaagaagctg gtgtcaaagt cgtgattgca actggccgcc
    17941 ctatcgcagg cgttgccaaa cttctagacg acttgcagtt gagagacgag ggggactatg
    18001 tggtaacctt caacggtgcc cttgtccaag aaactgctac aggacatgag attatcagcg
    18061 aatccttgac ttatgaggat tatctagata tggaattcct cagtcgcaag ctcggtgtcc
    18121 acatgcatgc cattaccaag gacggtatct atactgcaaa tcgcaatatc ggaaaataca
    18181 ctgtacacga atcaaccctc gtcagcatgc ctatcttcta ccgtacccct gaagaaatgg
    18241 ctggcaaaga aattgttaaa tgtatgttta tcgatgaacc agaaattctc gatgctgcga
    18301 ttgaaaaaat tccagcagaa ttttacgagc gctactccat caacaaatct gctcctttct
    18361 acctcgaact ccttaaaaag aatgtagaca agggttcagc cattactcac ttggctgaaa
    18421 aactcggatt gaccaaagat gaaaccatgg caatcggtga cgaagaaaat gaccgtgcca
    18481 tgctggaagt cgttggaaac cccgttgtca tggaaaatgg aaatccagaa atcaaaaaaa
    18541 tcgccaaata catcactaaa acaaatgacg aatccggcgt tgcccacgcc atccgaacat
    18601 gggtactgta aaaggaaaga atagactaaa accgctcagc tgagcggttt ttgatgtcta
    18661 attacatgcc ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat
    18721 ccattgaact aagggagcta gataaaaact ctgctgaaaa agcagagttt tttagtcgaa
    18781 ttaacgacgg atttctttga tacgagctgc cttaccttga agagcacgca agtagtacaa
    18841 tttcgcacga cgtactttac cgtaacgtac aacttcgatt ttttcaacac gtggagtgtg
    18901 gattgggaag atacgctcaa cacctacacc gttagagatt ttacgaactg tgtagttttc
    18961 tgagattcca gcacctttac gtgcgataac aacaccttca aaaatctgga tacgttcacg
    19021 gttaccttcg acaactttcg catgtacacg aacagtgtca ccaggacgga atgatgggat
    19081 atctgtacga agttgacctt cagtcaagct ttggattaat ggattcattt tattctccta
    19141 tctttgtcaa tcttgaggaa tcttcctcag cggataaact gtatttttgt gcgtccatta
    19201 cacacaagat atagtttacc aaatttctaa aaaaaagtaa agaaatttat agcaaaattc
    19261 ctaaaaaaat cgcaaccaaa ccacctatgt aagtcaaagt caggtaagaa taaaagacct
    19321 tcttatcact tagcagtctt tgaagttcgt cattcaaggt cgaaaaagtt gttaaaccgc
    19381 cacaaaatcc tgttgctaga atagcatata cttccttaga ctctacatga ttgtaaaata
    19441 ctccaattaa aaaacaacct aaaagattag ctatgagcgt tccgagtggc aatttagaag
    19501 cttgattata gcgagaaaag aaataccgta cgagtgctcc caagccacag gcgattgcaa
    19561 gatagacgat taccatttct tcctccctag aaaataagct aagagtaggc ctccaccgat
    19621 gctcaaaagc aaatacagga ctaaactaaa ataacgccct gtatcaagca gcttcacagt
    19681 atcaagcatt aggctggaaa aagttgttaa acctccgcaa aaacccgtcc ccagtgctaa
    19741 aatcaagccc ttactagtcc ccttatagac cagatagccc ttgacaagaa aaatcaagca
    19801 gaaaattccc agatagttga caaagagagt gccccaagga aagtctggac tggctggtaa
    19861 ccaggtggaa actagatatc ggacaagtcc gcccaacata gcagctagaa aaattcctag
    19921 cggataaaat tgttcttttt tcatttgata ttttgatcct gataatcacg cgaacgtttg
    19981 agtatgtccg aaaaagtcgc tacaatagtc tcctgatagc gcttgtcctc tacacgactc
    20041 ccaacctttt caaaaataac ttcttctctc ttagtatcta aaatcggttt acctgaagct
    20101 ttcttataag caaccacccc ctcaactaaa tgcattcgtt cttctaacag tttgacaatt
    20161 tggtcgtcga tttgatcgat ttcttgacga ataatatcta aatccataca gtctcctcct
    20221 ttatttgaat tattgtatca aaaagccatc aattaggcta gtaaaatccc aactctcgat
    20281 aagaaaaatg cactgattga ttacatcagc gcacttttat gcttatccta ctttagcaac
    20341 caattcttct gcgaattgtt ccaagcgttc aatatcttct tcctcggcag aaagatcaac
    20401 tttgacacac tcagaacctt tttctgctcc tgttgaaaca aagacacggt caaagtcatc
    20461 aacagcctta cagaattcat cgtagaaggt atctcctgag ccgaccactc cgtagatttt
    20521 gccattcaag ttgagatctg ctagatcttc gtagaagtcc atcatctcat ctggcaattc
    20581 accatcacca taagtatagg tcgcaacgat agcgatgtct gcttccaaga agtctgaagc
    20641 gtcaacagtt gtacattcat caacatcaac atccaagccc aagtcacgta atttgtctgc
    20701 tacaatatct gcaatttctt cggtattacc ggtcatactg gcaaatacaa tttttgctaa
    20761 tgccatatcg tcctcctcaa tttatctttc tccattatat cacatctttt tcattttaaa
    20821 aataaaaatt cttgtgctac aatgaaatga gaaagaattg aggttattta tggagatttg
    20881 ccaacaaatt ttagaaaaaa ttaaagaata cgacaccatt atcattcatc gtcatatgaa
    20941 accagaccct gatgccttgg gaagtcaggt gggattgaaa gccttgctgg aacatcattt
    21001 cccagaaaaa accatcaaag ccgtcggttt tgatgaacca actcttactt ggatggctga
    21061 gatggatctt gttgaagata gagcctacca aggcgcactt gtcatcgtct gtgatacagc
    21121 taatactgct cgtatcgatg ataagcgcta tagtcaaggt gattttctca ttaagattga
    21181 ccaccatcca aatgatgatg tatacggtga cctgtcttgg gtcgatacta gttcaagtag
    21241 cgctagcgag atgattaccc tatttgccca aacaacccaa ctagccttgg cagatcgcga
    21301 tgctgagttg ctctttgcag gaattgtcgg tgatacaggt cgcttcctct acccttctac
    21361 cactgcacgg actcttcgcc tggctgctta tttgagagaa cataactttg actttgcggc
    21421 tctcactcgc aaaatggaca ctatgagcta caaaattgct aaactgcaag gctacatcta
    21481 cgaccatctg gaagtggatg aaaatggtgc tgctcgcgtt atcctgagtc aagaagtctt
    21541 gaaacaatac aatgtaaccg atgctgaaac tgcagccatt gtcggtgcac ctggacgcat
    21601 tgacagagtg agtctctggg gaatttttgt cgaacaggct gatggccact accgagttcg
    21661 cttacgcagt aaaatccatc ctatcaatga aattgccaag gagcatgatg gtggaggcca
    21721 ccctctagca agtggtgcta attcctatag cctagaagaa aacgaaatca tctaccaaaa
    21781 gttaaaaaac ttgcttaaaa actgataaaa tacttgccaa acttttcaga atctgataga
    21841 ctagtatggt aacaatctat ggctcgcaaa gagaccatgg cagaaaggaa atattgcaaa
    21901 atgaaaaaag atatccatcc agaatatcgc ccagttgtct tcatggacac aactactggt
    21961 taccaattcc ttagcggttc aacaaaacgc tctaacgaaa cagttgagtt cgaaggcgaa
    22021 acttacccat tgatccgtgt ggaaatttca tcagactcac acccattcta cactggacgt
    22081 caaaagttca ctcaagcaga tggacgcgtg gatcgtttca acaaaaaata cggtctcaaa
    22141 taatgataaa agaacagttt cgactgttct tttttgtttc ttgaaatcaa ctgctgtttt
    22201 catgttccag actcatctgt aggttcggtt tccatgctac taggcaggaa ggaaatagct
    22261 gtttcaacac gtccataatg agctgtacta ttgtcacgaa ccacactttc attgatggtc
    22321 caagtggaat tcattttctt aaaagcttct cggacttttt ccaaatcttt ggaggcaatg
    22381 gcctgctcta aggtttcaaa acgaggactt atactcatct gctttcacaa agcattctag
    22441 tccatctccg attaacgatg gactttatca cctccttctc cagtccttgt ataacatctt
    22501 ggagttgatt catgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
    22561 gaatctcttt ccacacttgt tcaatgggtt catctctggt gtgtatggag gaataaaggt
    22621 aaaatcaata ttagtcggaa tatttaaggt acttgattta tgccatatag cattgtccat
    22681 aacgagtaaa aggataagct tgtgaaagct cttctaaaaa ggcgttcatc cacactcctt
    22741 tttataagcc tgaaataagg catcaattgt aacaaattct cctgcctctg cagccttcaa
    22801 atggcgagca agaaaggctt tctcttcctc aactgtcata tatgcatgat tacgaccacc
    22861 acgtgtttct tgaaggagag agtcgagtcc gaactcctca tattttttta catttcgcca
    22921 aatcgttgtt tgattacagt ctaaaagttc tataatctct ttataagatt tgcccatcag
    22981 acgaaatata gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa
    23041 atcgatttga ctgtcctgat cgatttgctc tgttcttgtt tcgttttact atag
//
LOCUS       DAVLTG010000029        23082 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLTG010000029 DAVLTG010000000
VERSION     DAVLTG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.029"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..425)
                     /locus_tag="VYN12_001255"
     CDS             complement(<1..425)
                     /locus_tag="VYN12_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415642.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILT"
     gene            complement(422..775)
                     /locus_tag="VYN12_001256"
     CDS             complement(422..775)
                     /locus_tag="VYN12_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1415643.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            1539..1859
                     /locus_tag="VYN12_001257"
     CDS             1539..1859
                     /locus_tag="VYN12_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1415644.1"
                     /translation="MQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(1912..2499)
                     /locus_tag="VYN12_001258"
     CDS             complement(1912..2499)
                     /locus_tag="VYN12_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1415645.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            2741..3412
                     /gene="sdaAB"
                     /locus_tag="VYN12_001259"
     CDS             2741..3412
                     /gene="sdaAB"
                     /locus_tag="VYN12_001259"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1415646.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            3421..4293
                     /gene="sdaAA"
                     /locus_tag="VYN12_001260"
     CDS             3421..4293
                     /gene="sdaAA"
                     /locus_tag="VYN12_001260"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1415647.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            4315..4947
                     /locus_tag="VYN12_001261"
     CDS             4315..4947
                     /locus_tag="VYN12_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1415648.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            4997..5209
                     /locus_tag="VYN12_001262"
     CDS             4997..5209
                     /locus_tag="VYN12_001262"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415649.1"
                     /translation="MKIKEQTRKLAAGSSKHCFKVVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVVDRTDEVSNHIRQGDVDVV"
     gene            complement(5295..7145)
                     /locus_tag="VYN12_001263"
     CDS             complement(5295..7145)
                     /locus_tag="VYN12_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1415650.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(7187..8344)
                     /locus_tag="VYN12_001264"
     CDS             complement(7187..8344)
                     /locus_tag="VYN12_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1415651.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            8402..9568
                     /locus_tag="VYN12_001265"
     CDS             8402..9568
                     /locus_tag="VYN12_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1415652.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            9707..10033
                     /locus_tag="VYN12_001266"
     CDS             9707..10033
                     /locus_tag="VYN12_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1415653.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            10020..10613
                     /locus_tag="VYN12_001267"
     CDS             10020..10613
                     /locus_tag="VYN12_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1415654.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            10606..11517
                     /locus_tag="VYN12_001268"
     CDS             10606..11517
                     /locus_tag="VYN12_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1415655.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            11579..12643
                     /locus_tag="VYN12_001269"
     CDS             11579..12643
                     /locus_tag="VYN12_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415656.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(12821..13681)
                     /locus_tag="VYN12_001270"
     CDS             complement(12821..13681)
                     /locus_tag="VYN12_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1415657.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIYLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(13803..14789)
                     /locus_tag="VYN12_001271"
     CDS             complement(13803..14789)
                     /locus_tag="VYN12_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1415658.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(15061..16536)
                     /locus_tag="VYN12_001272"
     CDS             complement(15061..16536)
                     /locus_tag="VYN12_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1415659.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKATDSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(16794..17717)
                     /locus_tag="VYN12_001273"
     CDS             complement(16794..17717)
                     /locus_tag="VYN12_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1415660.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(17731..18660)
                     /locus_tag="VYN12_001274"
     CDS             complement(17731..18660)
                     /locus_tag="VYN12_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1415661.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(18979..19329)
                     /locus_tag="VYN12_001275"
     CDS             complement(18979..19329)
                     /locus_tag="VYN12_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415662.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRNILQTVKDAI
                     VSLESIKESQSATKDGGQTVGKETVDKDVLENSQEELQKAVLFLADEKGSEHTAAELI
                     DNLKEVIAKLKANA"
     gene            19409..19546
                     /locus_tag="VYN12_001276"
                     /pseudo
     CDS             19409..19546
                     /locus_tag="VYN12_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(19650..19805)
                     /locus_tag="VYN12_001277"
                     /pseudo
     CDS             complement(19650..19805)
                     /locus_tag="VYN12_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19991..20602)
                     /gene="rpsD"
                     /locus_tag="VYN12_001278"
     CDS             complement(19991..20602)
                     /gene="rpsD"
                     /locus_tag="VYN12_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1415663.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(20797..21849)
                     /locus_tag="VYN12_001279"
     CDS             complement(20797..21849)
                     /locus_tag="VYN12_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1415664.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(21846..22544)
                     /locus_tag="VYN12_001280"
     CDS             complement(21846..22544)
                     /locus_tag="VYN12_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415665.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(22711..>23082)
                     /locus_tag="VYN12_001281"
     CDS             complement(22711..>23082)
                     /locus_tag="VYN12_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1415666.1"
                     /translation="LDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHA
                     TGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGF
                     LGLALAGLLGGLGLKNKKEEN"
BASE COUNT         6909 a         4936 c         4247 g         6990 t
ORIGIN      
        1 gttaatataa aactagaaat ctctaaatat tttatccaag aagattgaga caccttgctt
       61 ctaaactgac taattttctt atattcgtta gtcaatttag tagcaaaatc ttccccaatt
      121 aaatgaaaga ttgctaactc taggataaaa acacttatta atacggtata agtcaaaaaa
      181 ctttctggga aaaacttatt gattaaaatg gggaaactca ttaacagaat cgaatttatg
      241 gctagacaga tagatactat tttatttttc acagaatata gaggtagtga tactattgag
      301 tagataaaag ctaaaaaaat aagcaaaaaa tactccgtgt catttataat cgccctgaat
      361 gataaaaata tatacatcca acatacgata atgtgtattt ttcgaatctt atctacatta
      421 ctcatcttac tgtcgcagat atgaatccat cccaaggata agggttcccg ctaatatcac
      481 aacctctatt aagagcacca tatccaatac agtaagctat tcttcctgcc gccccagcca
      541 atacacctgc tgctgcacca ataagccaac ctccaaggcc tccaacttta atatagttta
      601 ttagtttttt ggttaaaact gcagctccag ctaatgctat aaaagttcct ggactcatag
      661 ctaaagctgc gcaaattcct tgacaagcac gcttgcttaa ataagctccc ccatcaaggt
      721 acatcatctc ttcttcatca atcacaacat aattatttgg taatacaagt tccatttatt
      781 ttctcctttt ttattaagca tggttaggat ggtttcctaa caagtgatcg caggctttgt
      841 ttagttacct aaattagact tcctttcttt atcttatttt aaatatttaa aaccagttac
      901 tgcttgaagc ttaacagttt acttaattca aataacagct aatcactgat tccctgattt
      961 tatcaaatat actaataaca acaattgtga tacgatcatc attataagaa caacatttaa
     1021 cgaatcaaag tttttccgag ataataataa agcaacagca agcagtatta ttactaaaga
     1081 ttgaataact actattactc ttaacatttt atcctccact aacaactcaa gctcccttac
     1141 attatatcga ccagccccat ggaaagatta tagctagact aatcaatgat ataatacata
     1201 ctagaataca aaatattttt ttattcatac tttttctcct atctttattt tctacctaca
     1261 tagtacctct tattaagctc atttcaaaat tacgttaact tttttcacga aaaggagaaa
     1321 attatgcgtt atgattatgg atagcgcttt caaattttta aactcctatc ccgtcctttt
     1381 atctatataa taagcataag cgaaaatata ataactgtca agtaactgaa gtgaatttta
     1441 taaaaaaatt acaagccaaa tttgtaaagt ttacactaag ccgctagggc aatcgtctat
     1501 cagaatgtcc gtttatttgt caataatccg agaaaatctt gcaacgctta gaagtctata
     1561 aaaactatca acatttatat gacttgcgaa tgacaattct attaaacctt tccacactct
     1621 atctatacaa tcaagataaa aacatgtgta agcaaatctg ctacacttta ctggaggacg
     1681 ccaagaataa gaaaagctac gataggctgg ctatctgcta tgtccgtatt gggatttgta
     1741 gggatgatgc gaaacttatc caaaaagggt tctcactcct agagctgacc gaggaaactt
     1801 ctatgctgtc tcatctcaaa aaagaagtag agacccatta tcaaccaaag aaattataaa
     1861 aaaagtcgag ggatttcctc gactctttac atattatttg ttcgttagtt cttaatacca
     1921 gccattgtta agccagaagt ttttagcagc agtccatgaa ccgtaacgtc ctgcaacgta
     1981 ggcatctgct acacgttctt ggttttcagc tgagtagtca ccgttcaggt atgaatctgt
     2041 taattggtaa cgtccgatat aacgtccatt tgtagctgta tagctaccac ctgattcttt
     2101 ttgagcgatc cattctttgg cttctgcttc agatccgctt acagttgaaa caactgtttc
     2161 acttactact ggagtttctg ctactggagc tgaaacagtt tcatcttgag cggctggtgc
     2221 cgcataagta gctggcgctg gtgttgcaac aggcgctaca gggccatcga taaccaactc
     2281 ttgatcaaca taaatcaaat gaatgttatc aatgtggttg ttttctgcca atttttcaac
     2341 tgttgtgttg tgagtttcag cgatttctga aagtgtatca ccttctttaa cagtgtaagt
     2401 tgatgattct tgagcagata caaatgatgg agcaaatact gcaaacaagg cagctactcc
     2461 tgcaagagtt gctttaatct ttttagttat tgatttcata ttcgaaaatt ctccttcttt
     2521 ctatagttct atcataccct ttaaatatta ccgtttcttg acacttttat gtagaaatat
     2581 tacaaaatta ttttttattt ccctaaataa ggtgtttttt gtcataaaag atactatttt
     2641 tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc ccctcattct
     2701 ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac ttcgttttca
     2761 atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc ataccgctgg
     2821 tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga cagaagttga
     2881 attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag acctagccct
     2941 tgttgcaggt attttaggaa tggatacaga tgatcctgaa attccaaata gtctggaaat
     3001 tgcccacaag cgtggtatca agattgtctg gaccattcag aaagacagca atgcccctca
     3061 ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg tgactggtat
     3121 ttctatcggt ggaggaaata ttcaggtaac cgaactcaat ggttttgccg tctctctcaa
     3181 tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga ttgcccttgt
     3241 tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca ctcgtgaaaa
     3301 agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg atgaggctat
     3361 cgaagaaatt cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat aggaggaagc
     3421 atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca aggaaatgtc
     3481 gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga agaagtcttc
     3541 cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg cctcaatgaa
     3601 aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggatca ctacatcgaa
     3661 aacggaaaaa ctctgtcaga ttatacgatt ctctcggctg cccgaaatgc catcgcagtc
     3721 aatgaacaca atgccaaaat gggcttggtc tgtgccactc caaccgctgg aagtgctggc
     3781 tgtctgccat ccgttctcac tgctgctatt gaaaaattag acctcagcca cgagcaacaa
     3841 ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa tgcctccatc
     3901 tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat gagtgctgcc
     3961 gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat tgcctttgtc
     4021 attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga agttccctgt
     4081 gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat ggccttggca
     4141 ggtatcgaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca agtaggagca
     4201 agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac ccctactggt
     4261 cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga aaccatgacc
     4321 tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc tatcgggatt
     4381 cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga tgccaaaact
     4441 attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct gtccaaagac
     4501 caaatttctg aagccgtgca gatatatcgt tcttactata aggcaaaagg catctatgaa
     4561 gctcaactct ttcctcagat tatagacttg cttgaggagt tatcgagcag ttatccactc
     4621 tacatcacca cgacaaagga tacatctact gctcaagaca tggcaaaaaa cttggaaatc
     4681 catcatttct ttgatggcat ttatggttct agccctgaag caccccataa ggcagatgtc
     4741 attcaccaag ccttgcagac acatcaacta gcaccagaac aagccatcat catcggagat
     4801 accaagtttg atatgctggg agctcgagaa acaggtattc agaaattggc catcacttgg
     4861 ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc tcacaaaccc
     4921 ttagaagttt tggcgtattt tcaatagcat agactgggta acaattccat ttcagaagaa
     4981 aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg cgggcagctc
     5041 aaaacactgt tttaaggttg tagatggaac tgacgaagtc agctcaaaac actgttttaa
     5101 ggttgtggat ggaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
     5161 tgacgaagtc agtaaccata tacggcaagg cgacgttgac gtggtttgaa gagattttcg
     5221 aagagtataa gtctctacat aataaaacgc atattaccaa ggttgtgtaa cttgatacta
     5281 tgcgtttttc ttttttattc aatgtgggtt gtttgattag caaaggcgat aatagcttgc
     5341 ttcaactcat ctccactgag agtgcggaac tctccaatct tttgattgat ggattctaaa
     5401 ggcatgacat taaccttacc aacgaaaatc ttatccataa cttgattatc aacgagttcg
     5461 gttgatacca agagttcttc gtagagtttt tcacctgggc ggattccaac ttcaacgatt
     5521 ggaatttcac tttcagtgtg gccacttaga agcaccatct tcttggccaa gtcataaatc
     5581 ttgactggtt tgcccatatc aaggataaag acttccccat ctttggcata agcaccagca
     5641 tggataacca gacggctagc ttctggaatg gtcataaagt aacgggtcat gcggaagtct
     5701 gtcaccgtta caggcccacc ttcagcaatc tgacgttcaa agactggaat gacactacca
     5761 cggctaccaa gaacattccc aaaacgaact gcacagtagg ttgattggct acgttggtta
     5821 aagccagtga caatcaactc cgccacgcgc ttggttgctc ccataacatt tggtggattg
     5881 actgccttat ctgtcgaaat cataaccatc ttagacactt tagcttcatc aacagcctta
     5941 gcaacattgt aagttccacg gatattgttt ttgaaggctt cttttggatt gcgctccatc
     6001 ataggaacat gcttgtgggc tgccgcatga taaacaatag caggtttgta ctgctcaaag
     6061 acttgcaaca aacgatcata gtcttgaatg tccgcaatca caggtacata atcaatccct
     6121 tggaacttac gaatcaattc atgataaaca aggtagattg agttttcccc atgaccgagc
     6181 aagacaatgc gttcaggatt gaagcgacta acttgacgac agatttcaga accgattgaa
     6241 cctccagctc ctgtgactaa gatggtctta cctgtcagtt ctgcacccag acgcgattcg
     6301 tcaagacgga tttcctgacg acccaaaagg tccgtaatat caattttttg gaagccagta
     6361 cctgcttggt gaaggccctg aacaacagtt tcaaccttag gcatcttgta acatttgaca
     6421 cccagcttat tacacatctg caagatacgc tcatattctg acggatccag cgacggaatc
     6481 gcaacgatga cacgctcgat ttgatggcgt ttggctaatt caggcagatt gtcataagag
     6541 cccaaaacag gaataccacc aagtttttga ccctttttct tagaatcctt atccaaaata
     6601 ccgaccagtt ctaattcact ggttggatgt tggtaactat ccataaaaag agccccacca
     6661 tcaccggcac caatcaagaa ggtccgacgg tgttctccat caccactacc ttttttgcgt
     6721 ctggagtaga ttaactgcca agtaatccgt ggcaataaaa tcaagaaggt actcaacaag
     6781 ataaagagaa tgatgaaacg gatggagaag agtggcaaga aggcataaca gatactatat
     6841 gacaagacac tgctagcagt cacaccaaaa aagattttca tgaaatccgt aatcttgctg
     6901 taacgactaa tgctcgcgtt caacccccaa aaaccaatca tcaattgata gaacaggaag
     6961 gccaaactcg tatagataat gtagtcaaca ggtgctggat taatcagccc ataaaataaa
     7021 atataagata caatgatgga aaccaccata ctgaaaatat caaatattcc ccagaaaacc
     7081 tgcttttgtt gtttatttaa aatttccacc agatcaatca cataatctgt tagtttttta
     7141 ttcatagaaa tctactcctc cttaaaagag ttttactata ttgttattat agcatatttt
     7201 gatttatttg gcttatttta tccaaataaa ttattgttct cttgtactcc ttcttccatt
     7261 taaatcctct aattaaacct acaatcgtcc caaggccata agcaaagtga atggaaaata
     7321 aaagaaaggg catcacaatt agaaatccat ttttatgttt taataaagtc agcaaagtga
     7381 gtaatgacaa aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg
     7441 gtaacaatgc tagactaaac acaagactca aaacaaataa acaaggaaca tagtgaaata
     7501 atgataaaca cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact
     7561 tttgatgcag cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc
     7621 tatagcggat tttataacca tattctcgaa ttctataatg aatatcatta tcttcagttc
     7681 ggccaagttg ctcatttact aaaccaacct tctggaaaac ctctcgttta tacattccat
     7741 gaaaaataga agaaacatat ctatcctcag aactatttcg ataattggca atgctactgc
     7801 caaacatatt ttcctcaaca agatgcaagg tctctgccca ttttcctttt ccttcgacaa
     7861 tcgtcggtct aggcccccca cagacaaatt caccttgttg aataatagcc acattgttca
     7921 ttacaaaagt ctcagtaact tttgaatgag catcaatttt taaaataagg tcccctacag
     7981 aatgtttaac tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc
     8041 taattgagtt aaactctgta tcttccttta taaattgctg aatgatagct gtggtcccat
     8101 ctgtggacat agcatttata aatagaattt caatattctc tttaggatag gtttgatttt
     8161 ttaagtcttc aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg
     8221 atacgagaag actttcaaca ttttgagtca ctactactct cctgaatttt tccttccacc
     8281 attctatcat aattttcaag actttcccat ttttatcttg aaagccagaa accttacttg
     8341 acattatagt gaaaaagcct taaaataagc tgttattaaa atcagctaga agaggtatta
     8401 tatgaaaaag caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg
     8461 aactcctttt actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga
     8521 agttagttcg cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc
     8581 attttctacc caactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt
     8641 cttcttgacc atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac
     8701 cttgatggtt ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc
     8761 caatcaacca aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc
     8821 aacggctctg gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact
     8881 tatccttctc ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg
     8941 ctataatcat agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa
     9001 taaacaggtt tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgt
     9061 catgacctgg ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt
     9121 gctgacttct atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac
     9181 aaccagttta tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt
     9241 ggtcggcatt tccatgctct ttttcccaat caataatttc atttactggc ttaccatcca
     9301 tctcctcatc ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact
     9361 caagacaagc gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta
     9421 tatcctagca gcctttgggc caaccctctt tggttacagt tttgacctgt tccactcttg
     9481 ggtaccagct gtagctgccc tcttgctcat ctatatcctg atgactgtgg ccctctttac
     9541 agtggacaga gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata
     9601 taaaaatttt acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag
     9661 aaaaattata tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac
     9721 atcctctgcc ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg
     9781 ttatgagatt agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc
     9841 cattctcaaa aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg
     9901 tcgcatgcgc aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa
     9961 agatgaatgg gcactctata cagacaccat caatggcatc atagaaggga gtatccgcca
    10021 tgacaagaac tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg
    10081 accgtatcga agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag
    10141 aagaagaact catcgctagt ttgggaactc ccaaagaagc ggcccacgaa gttctatcca
    10201 atcttctcga taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac
    10261 atatcgcctt gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc
    10321 tcgtgaccct gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag
    10381 tttccatact gggtatcatc ggcggattcc tatttttagt tgaaagtttc actatcctcg
    10441 cccaagccaa atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt
    10501 cttcgctagt tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc
    10561 gtctggtaca atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca
    10621 aaaggatttc tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta
    10681 ggtatccaat ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat
    10741 agccgtacgg aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac
    10801 caacacacgc tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca
    10861 tctctttctg ctcaccatga ttttatcacc aatcagaacg atagaactct gagtctcact
    10921 gataagaaac tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc
    10981 gcaagtagct actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact
    11041 ctaaaaggga tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt
    11101 gaaaatgcga ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa
    11161 aacagtaaac tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt
    11221 cagctagagt caacagataa tcacttccac gctgaaaata tccaagtcca tggtaaggtt
    11281 gaactgactg ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt
    11341 aactgggaca tctcaagtaa ctacggttct atcttccaat tcacaagaga aaagcctgaa
    11401 tcaagaggta cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa
    11461 ctcattgcga gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa
    11521 aaacgcttac atctgctact atggaagcat atttatctaa ccaaaaggag gttctaccat
    11581 gaaacaagaa tggtttgaaa gtaatgattt tgtaaaaaca acaagcaaga acaagcctga
    11641 agagcaagct caagaggttg cagacaaggc tgaagaaacg atagccgatt tcgatacacc
    11701 aattggaaaa aatactcaag tagaggagga agtctctcaa gctgaagtcg aactggaaag
    11761 ccagcaagaa gagaaaattg aaactcctga agtcggtgaa gcgagaacag aaatagaaga
    11821 aaagaaggca tctaattcta ctgaagaaga gtcagacctt tctaaagaaa cagaaaaagt
    11881 cactatagct gaagagagcc aagaagctct tcctcagcaa aaagcaacca cgaaagagcc
    11941 gcttcttatc agtaaatctt tagaaagtcc ttatatcccc gaccaagctc caaaatctag
    12001 ggataaatgg aaagagcaag tgcttgattt ttggtcttgg ctagtggaag cgatcaaatc
    12061 tcctacaagt aagtttgaaa caagtatcac acacagttac acagcctttc tcttgctcat
    12121 tctgttttct gcatcttcct ttttctttag tatctatcac atcaaacatg cttactatgg
    12181 acatatagca agcattaaca gtcgcttccc tgagcagcta gctcctttaa ctcttttttc
    12241 tatcatctct atcctagtag cgacaacact cttcttcttt tcattcctct tgggtagttt
    12301 cgttgtgaga cgatttatcc accaggaaaa ggactggaca ctagacaagg ttctccaaca
    12361 atatagtcaa ctcttggcaa ttccaatctt cctcactgct attgctagtt tctttgcttt
    12421 ctttgatagc ctacgattta cagccctctt gtgtgtgatt agcattggaa tcattctgct
    12481 tgccagtctc catatcatta caagaccaag tcaagcaagt gaaaccgact ccttctatca
    12541 attattcttg tctgtccttg tgaacggagt tattatcctc ctcttctttg tagctgaagt
    12601 ggcactgatt ggagattatc ttcgtatctt ggcctttctt taaacttcat actcttcgaa
    12661 aatcaaattc aaaccacgtc agcttcgcct taccgtactc aagtacagcc tgcggctagc
    12721 ttcctagttt gctctttgat tttcattgag tagcaatcct gtcatccttg gcaggatttt
    12781 ttctatgtca aaaaagcaag tcgattgacc tgcttctgct ttacttttct tgtgctaatg
    12841 ttttaaaatc ttgtcctagg atgggttgta tttctatttg attggcgtct agttggtggt
    12901 aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagct atggattcat
    12961 agtcttctgg tttagagccg tctcctgtga tttgaaccaa gtaaatctcc cactggactt
    13021 ccttatccac caattgctca atataggctg caggaacaaa cggttctctc ggtaaaactg
    13081 tcttgactcc ttgagctaaa tggtaaacgc catgcacttt tccttctcca tcctgataga
    13141 aggaaactct tgcaaagtag gcatctgtct cttgaaccgc acgcacacgc gcttcaaact
    13201 gagccaagcc atctgcctct aaaaagcttt tcaagttctc acgactaaag aaaataggat
    13261 taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag gcttgaatac
    13321 ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca gtccctgtat
    13381 aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtcttt gttagtaggt
    13441 caggaagatc gacacggtaa gccttttgac catcagcata actgacctta aagagaaatt
    13501 gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc tgacgaagat
    13561 agactacatc atagctatgt gactccaaac cgtctagcaa ggccaagatc gacttggcat
    13621 tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat gtttttgcca
    13681 taactggact cctttgaaat cgtttacata cagtatacct tattttcctg aaagatacaa
    13741 aaacaaactt tagatttttg agtacaaagc atagaaaaac agcccctgag gactgtttga
    13801 tcttatacag tagctgcctg atccaagctt tcaccgatag cggctaggcg ctcaatcact
    13861 tcagcttgtg tcaattcatt ttttgaaaca tagcggttac gtgggtgaac acggcactcg
    13921 tgtgagcatc cacgaaggta cttgtcttca ttttcttctg atgtcaagat acgacggtta
    13981 cagaagggat ttccacagtt gacataacgt tcacatggtg ttccatcaaa ccagtctttc
    14041 cctacgatgg ttgggttgac atggttgaca tcaacggcaa tacgctcgtc aaagacgtac
    14101 attttcccat cccaaagctc accttgaact tctgggtctt taccgtaagt tgcgattcct
    14161 ccgtgcaatt ggccgacatc tttgtagcct tcacggacca tccagcctga gaatttctca
    14221 cagcgaacgc cacctgtaca gtaaaccacg acacgcttgt ccatgaattt ttccttgtta
    14281 tcacggaccc attgtggtaa ctcacggaag ttgcgaatat ctgggcgaat agccccacgg
    14341 aaatgtccta ggtcgtactc ataatcgtta cgtgtgtcaa ggacaacggt atctttatca
    14401 agaagcgctt ctttgaactc ttttggagac aagtaagcac ctgttgtttc aagtgggttg
    14461 atgtcattgt caaagtcgtt gtcttccaaa ccaaggtgga caatttcttt cttgtagcga
    14521 acaaacatct tcttgaaggc ttgttcattt tcttcgtcaa tcttgaacca gagatcttcc
    14581 atacctggga ggctgtgaac gtagtccatg tatttttgag ttgtttcata gtcacctgaa
    14641 actgttccgt taattccctc gtcagcgact aggatacggc ctttaaggcc gattgattta
    14701 cagaaagcca agtggtctgc agcaaattgc tctgcatttt caattggagt ataaaggtag
    14761 taaagtaaga cacgaatatc ttttgccata agatttgttc tcttttctat tcttaaattt
    14821 tctaaatttt ttatttatcc atactagtat acctgcttga gaaaacgaat gcaatttatt
    14881 tgactggaaa ttgtagagga ttctcgaaat ttcctgaatg gttaaaataa ggacaagaga
    14941 aaacagggat atctatatcc ttgtgccaaa aaaaccactg ccctccccag atcaacctga
    15001 ggaaagcagt gattcttatt ttaggagtta ggaatgaata cacgaaatca atttagctga
    15061 ttattttttg tttttcaaga attcatcgta ttgtttttgc atttcgttca atactttttc
    15121 gtaggcacct tcagatttca atttttccat caattctgga atcgctttat ctgggtctac
    15181 agtaccagtg ttgatagctg tatcaaattg ttgcattgtg ttagcaatag ctgagatttc
    15241 agatttcaca ttgtcagtat taaagataaa tccaagcgct ggagattctt tagcttctgc
    15301 caattctttc ttagaatttt cgatttgttg gtctgtaacg ttttcgttga tgtaaaggat
    15361 ccagttgtta ccagtgttcc atccacccat gtgagtgttt cctttgtagc catcaagaac
    15421 gcgaacacgg ttttctttac cttcaatttt ttcccagttc ttgccttctg gaccgtaaac
    15481 aagaccgttc aagagttctg ggttcgtatt caagaggttc aagatttcca ttgatttttc
    15541 tttgttctta gagttgtttg agatgacaaa gttagcaact tgtgttgttt ggtttttctt
    15601 gatgaagtta gtaattggtt tgatttggat atctttgttg gcaacacgtg aaagcaagct
    15661 gttaccgtag tcagctggtc ctactgtttc ttcacgaacg aaccaagtat cttgttgaag
    15721 gtcaaaggaa gtatcgcttg ttgcgacgtc ttttggaatg tagccagctt catagaattt
    15781 gtgaagagtc ttcaagtgtt ctttgaaacg aggtacttcg taacggttta caactttagt
    15841 agtatcgcct tcaaggtcaa taacgaatgg aagaccgttt gctactgggt agtcaaagtt
    15901 atcagatggg atgaaaactt taccaatagc aaatggtact acgtctggag ctttttcttt
    15961 gatttgtttc aagactggct caagagtttc gtaagaagta acacctgaaa tatcgatacc
    16021 atatttggca aggagagttc cgttgaaggc aaagttttga gatgatgcta cgttagctgc
    16081 aactggtaca gcataaatct taccatttac agtattaccc ttgatataag ctggatcaag
    16141 tgccttgtaa aggtctttac cttctttttt gtacaattct gtcaagtcag cataagcacc
    16201 tttttgagca tttacaatat agttatctgc aaaggcgata tcatagtttt caccagatga
    16261 tgtgataact gacattttct taccatagtc accccagcca aggtattgga tatccaattt
    16321 agcaccaact ttttcttcga tgattttgtt ggcatttgct aacaattcat ccaagttatc
    16381 tggtttgtca ccgatttggt acattttgat aacaggtttg tcacctgaat cagtagcttt
    16441 tttgctgtta cctgtcaaat ttccacaagc agcaagacct gcagccaaag cgactacact
    16501 agcagatgca aaagcatatt ttttccagtt tttcatgatg aaaactcctt tttttatttt
    16561 taaacttata aacaatgtaa tgatcttata ctcaatgaaa atcaaagagc aaactagaaa
    16621 actagccgca ggttgctcaa aacactgttt tgaggttgtg gataagactg acgaagtcag
    16681 ttacatatat ctacggcaag gcgacgttga cgcggtttga atttgatttt cgaagagtat
    16741 taacttcaca caagggaagt tgggaactga gaaatgttct ttttcaataa gcactattct
    16801 ttcacaccac cgatagtcaa accttttaca aagtagcgtt ggaagaatgg atataaaatc
    16861 gcgattggaa gggttgcaac cacaaccatg gccatacgac ctgtttcttt cggtagagca
    16921 actcccagtt gaccagtcaa accgaccgct ttggcaatgt agtccatatt ttgttggatt
    16981 tgcatgagca aatattgcaa tggatacaag ttatcactct tgatgtaaag aagggcgttg
    17041 aaccagtcat tccagaaacc aagagctgtc aaaagcgtga tggttgcgat acctggtagt
    17101 gacaatggca aacagatttg gaagaaaatc cgggcctcac tggcaccatc gatacgagcc
    17161 gattcgagaa tggcttctgg aatggtcttc ttgaagaagg aacgcatcaa gatgatattg
    17221 aatggtgaga gaagcattgg aacaatcaag gcccaaacag tgtcaccaag ctgaagtaca
    17281 cgggtcacca tgatataacc tggtaccaaa ccagcgttga acaacatact gagaaggacg
    17341 aagatggtaa aaaatctgcg atacttaaag gttgtccgtg aaatagcgta ggcataggtt
    17401 gttgtgataa agacatttgt caatgtccca actacggtta caaagacaga gatgaagagg
    17461 gcttgtagga ttttatcctt aaactgtgcc aaaaactcaa aaccgtctaa gccaaattgg
    17521 gatgggaaga agctatagcc gtattggagg aggcttttct cgtctgtcac tgaaataatg
    17581 ataacgaata caaaaggtag gatacaagag agggcaatca aacccgaaat gatactgaag
    17641 aagatatctg ctttcttact gaaggagtga atgccgacat tatcaatttt ttctttttta
    17701 attttctttt ttgccatatt ctcctccttt ctagaacaaa gctgagtttg gatcgactcg
    17761 tcttgcaagc aagtttgata ggataaccag aatcaaacca acaacggatt ggtaaagacc
    17821 ggctgctgca gccataccga tatctgctgt ctgagtcaaa ccattaaaaa catatacgtc
    17881 caaaacgttg gttacattgt aaagctgacc agcattgtgt gggatttgat agaagagacc
    17941 gaagtctgcg cggaagatat ttccgactgc aaggatggtc aatacagtta caagcggagt
    18001 caactgagga atggttacgt tgcgaatacg ttgccacttg ctagctccgt ccactgtcgc
    18061 tgcttcgtag taggttggat caattcccat gatcgtcgca tagtacatga cactgctata
    18121 tccaaaacct ttccaaatac ctaggaaaag taggagatag ggccagatgc ccaggtcagc
    18181 gtagaaattg acttctttga gaccaagact ttccaataga tgattgaaca cccctttatc
    18241 aatatttagg aaggcatctg taaagaaact gatgataacc caagacaaga agtaagggaa
    18301 caacatagaa gtttggaaaa tcttcaccat tctcttagaa cggagctcgc tgaggataat
    18361 ggcaatccct acagatacaa ctaaacctag aaagataaag ccaagattgt agaggacagt
    18421 atttcgtgtg ataataaagg cgtctcttga actaaataag aatctgaaat tatcgagtcc
    18481 gacccattta ctatttatga tactatctat gaaaccatta ctggtcatgt ggtagtcttt
    18541 gaaggcaacc acgttcccaa atactggaat gtaaaagaat agaatcaacc agagtgcccc
    18601 tggcaaaacc atcaagagaa agatccagtt gtctctcaat gtttttgaaa actttttcat
    18661 aatttcctcc ctttttattt tgatatccat ctaaaaattc ttttttagac ttttgataac
    18721 gattacatta ttagtatact cctatttgca ggttaggtta aactcctaat tatagaaaaa
    18781 actccacaaa ttatgtagca gatttaaaac tttatcacca ctatcaaaca aatgtcctaa
    18841 atcaattgtt tattttatct ctattagccc agtgatggcg tcactctgtt ataagcatcc
    18901 aacaacgggg tatactgaaa aatctccaga ctagggaact cagcgatagt tcctaatctg
    18961 gagattttta atatgttatt aggcgtttgc tttcaactta gcaataacct ctttaagatt
    19021 atcaatcaac tctgctgcag tatgctcaga gcctttttca tctgccaaga acaaaactgc
    19081 tttttgaagt tcttcttgag agttttcaag gacatcctta tctactgttt ctttgcccac
    19141 tgtttgtcct ccatccttag ttgctgactg gctttcctta atggactcta gggaaacaat
    19201 ggcatctttg actgtttgca agatattacg taaaccttgc tctgtcaaac tatcatctgc
    19261 aaaagctttc ttagcctctg ccaaaaccag acgtgctgaa tctgtggtag gattcgatac
    19321 acctgtcaat gatctcaaaa gattttctaa ggtttgagtc tgcttactaa tactagacta
    19381 aaatcaaaaa gtattatata acagtgatat gaaatcaact aaagaagaaa tccaaaccat
    19441 caaaacactt ttaaaagact ctcgtacagc taaatatcat aaacgccttc aaatcgttct
    19501 attttgtctg atgggcaaat cttataaaga gattatagaa cttttatagt agtttgaaat
    19561 aagatgtgaa catctctatc aggaaagtca aattaattta tagaaatatt ttagcagcca
    19621 aggtgtactg ttatagattc aatacactat acttggtggt ttagctctcc tgttttctct
    19681 tttagcttta accagccata aatggtatta cgtgagattt ggaaaacgtg tgatgcttct
    19741 gttatactac ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat
    19801 gccataaaag gattatacca cattgtgtac tatttttggt tcattttact atatcacttt
    19861 ggactatatc ggtctagtta tgtctcaacg attatagctg gatactaaga gaaatcaaaa
    19921 aagcactaag ggagaacgtc ccaaagtgct taatatcaag gcctcaaagt ctatcttatt
    19981 caataaaata ttacaacatt ttgttgtaga attcaacgac aagtgcttcg ttgatttctg
    20041 ggttgatttc gtcgcgttct ggcaagcgag tcaatgaacc ttccaacttt tcagcgtcga
    20101 atgatacgaa tgctggacgt ccaagagtag cttctactgc ttcaaggatt gctggaactt
    20161 tcaatgattt ttcacgaact gagatcactt gacctggagt tacgcggtat gatgggatat
    20221 caacgcgttt cccgtcaaca aggatgtgac cgtggtttac gaattgacga gcttgacgac
    20281 gagtagtcgc gagaccaaga cggtaaacaa cgttatccaa acgacgttcc aaaagaagca
    20341 taaagttgaa acctaggatt ccgcctttga tttttgtagc ttgtacgaac aagttacgga
    20401 attgtttttc acctacaccg taagtgaaac gaagtttttg tttttcagcc aattgcaaac
    20461 cgtattctga caatttagaa cggttgtttg gtccgtgttg tcctggtacg tagttacgac
    20521 gtgccaattc tttacctgta cctgtaagtg aaaggccaag gcgacgagct tgtttccaag
    20581 atggtcctgt ataacgtgac atatgaatgt cctcctgata taaataatat ttcggtggaa
    20641 atagtcactt agaaagccct gattcgtgca gatgcccttc gcctaaacag ccaaggttac
    20701 ttgtcataag acacctgttg acgagcttca tgctttcctg ctgatatttc acacaaaatc
    20761 tattctacca tgaatagctg gatttgtaaa ggggttttag gctttatttt cactaccaga
    20821 gaggttgaga acgagggtaa aggtacttcc tagaccgtac tggctgctga ctgtgatttc
    20881 cccacccaat tgatgggcca attcacgcgc aatcgcaagt cctaatccat gaccacctgt
    20941 cttcatgtta cgcgaagttt cgacacgata aagacgtttg aaaatatttt ccaaatcctc
    21001 tggggcaata ccctgccctt catcggtcac actgattgaa agctggtcct tctccagctt
    21061 agccaccact tccagcttgg ttcctggagc agaatattta aaagcgttat cgaccagatt
    21121 caccaagata cgagaaagct tagcataatc tccctcaatc cgggcagact ctgggattac
    21181 ctgcaagtgg acatctcttc tctcctgctc aatcaaaaac tgaaattcac tcatgcactc
    21241 aattaagagc ttgtccagaa aaatactgtc tttactggta gtttccacct gattcctagc
    21301 tgtgtttagg gtcaaaaaat tcaactcctc aaccagttta ttgagcctct ccgtctggcg
    21361 tccaatggtt gctagataat gagcttgctc cgactccttg ataatcccat ccaaaatccc
    21421 ttctaccgtc gcttggatcg aagtgatagg agtcttaata tcatgcgaca actgggcaat
    21481 catcaagccc ttttctcgtt cgctttcttc caaggaatca aagcttacct gcaaatcatg
    21541 ggacatctca ttaaaagttt gccctaattg ctgaaattct acaggacctt gaacctccaa
    21601 atttgaagga aaatccttgg ccgctacccg cttggcatgc tccttgagtt tgcccaacga
    21661 cgtaaagact ggcaatagga gaaagagact aatcccagca ccgacaaggc tggcaacgat
    21721 ggtcatccca agcaaaaagt aaatctcgcc tttcgcaatc agcatttttt gaacagccca
    21781 aaaaacaacc aaaatggtta agagggttga aataatatat ccaaccaaaa tataactttt
    21841 tagtttcatg tttgtcctct cggtttctct atcttatatc ccaaccccca aactgtctta
    21901 atagtgggcg tttggtcact actatatttt gccagctcct gtcgaagagc atggatatgc
    21961 acattcaagg tattggtgtc atccacgtag tcttctttcc agatcttttc atagaggtct
    22021 gtcttggaga aaactcgctc tggattgcta gctaaaatcc acagcaattc aaatgattta
    22081 acagttaaat ccagcatttc ttctcctatt tgaacttcat gactactatg attcattttt
    22141 agattgccaa gggaaatcag ctctgtttcg cccccacgat gaaggcggcg caaaatattg
    22201 tggacacgca aaaccagctc acgtgggcta aaaggcttag caataaaatc atctgctccc
    22261 aagctcaggc cgtaaatctt gtcctgttca ctggtcttag cagtaataaa taggaaaggc
    22321 tgctctggtg ataagtattg aacctcactg attaaatcat aaccatccat ccgaggcatc
    22381 atgacatctg tgataatcaa atcaatcggt tttttcttga acagctctag cgcttccagt
    22441 ccatcatggg ctaccaagac ctgataacct gcctgaatta agtatctctg atgaatatct
    22501 gtgatttcta cctcgtcgtc aacgagtaaa attgtctttc ccatctgtct ctcctttgat
    22561 aaaaacagtg ctatactgct ttaagtataa cactattttt attgttttac gatgatttta
    22621 atctgctatt gaaagaaagt cctgattgct gattgagttg ttaaactaat cttagtcagc
    22681 ccactatcca tcatttattt ccttagctga ttagttttct tcttttttgt ttttcaaacc
    22741 tagaccaccg agtaaacctg caagcgcaag cccaaggaaa ccaatacttg ccattgatgt
    22801 ttgagtctca ccagtatttg gtagcatagc tttatcctct gacatcatcg tatcagacat
    22861 cttgttagca gaagcagcca tgttttcacc tgccatcgtg ttggtagaac ttgtcatggt
    22921 gtcagcaggc atgctatctg tagtacctgt agcatgattg tgattcatcg gagtcacgcc
    22981 agaaccagag ttagaaggtg ataatgaacc atttgctgtg tctgatgttt ctttaacatt
    23041 tatcttaata gtgacttttt tagttgctac gatgttgtcc aa
//
LOCUS       DAVLTG010000030        22602 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLTG010000030 DAVLTG010000000
VERSION     DAVLTG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.030"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            115..279
                     /locus_tag="VYN12_001282"
     CDS             115..279
                     /locus_tag="VYN12_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1415667.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            363..929
                     /gene="amaP"
                     /locus_tag="VYN12_001283"
     CDS             363..929
                     /gene="amaP"
                     /locus_tag="VYN12_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1415668.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            941..1111
                     /locus_tag="VYN12_001284"
     CDS             941..1111
                     /locus_tag="VYN12_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1415669.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1150..1758
                     /locus_tag="VYN12_001285"
     CDS             1150..1758
                     /locus_tag="VYN12_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1415670.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1789..1992
                     /locus_tag="VYN12_001286"
     CDS             1789..1992
                     /locus_tag="VYN12_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1415671.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2102..2380)
                     /locus_tag="VYN12_001287"
                     /pseudo
     CDS             complement(2102..2380)
                     /locus_tag="VYN12_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2578..2865
                     /locus_tag="VYN12_001288"
     CDS             2578..2865
                     /locus_tag="VYN12_001288"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1415672.1"
                     /translation="MIVSLKTKSRKAKDIAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3143..3913)
                     /locus_tag="VYN12_001289"
     CDS             complement(3143..3913)
                     /locus_tag="VYN12_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1415673.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3928..4776)
                     /locus_tag="VYN12_001290"
     CDS             complement(3928..4776)
                     /locus_tag="VYN12_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1415674.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIANTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHSAGAPWWLQVPNVCWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4773..6248)
                     /locus_tag="VYN12_001291"
     CDS             complement(4773..6248)
                     /locus_tag="VYN12_001291"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1415675.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6571..7926)
                     /locus_tag="VYN12_001292"
     CDS             complement(6571..7926)
                     /locus_tag="VYN12_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1415676.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(7936..8253)
                     /locus_tag="VYN12_001293"
     CDS             complement(7936..8253)
                     /locus_tag="VYN12_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1415677.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8270..8587)
                     /locus_tag="VYN12_001294"
     CDS             complement(8270..8587)
                     /locus_tag="VYN12_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1415678.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLPGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8602..9498)
                     /locus_tag="VYN12_001295"
     CDS             complement(8602..9498)
                     /locus_tag="VYN12_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1415679.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9501..10763)
                     /locus_tag="VYN12_001296"
     CDS             complement(9501..10763)
                     /locus_tag="VYN12_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1415680.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11043..12221
                     /locus_tag="VYN12_001297"
     CDS             11043..12221
                     /locus_tag="VYN12_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1415681.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQIILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12449..12895)
                     /locus_tag="VYN12_001298"
     CDS             complement(12449..12895)
                     /locus_tag="VYN12_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415682.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRVQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12965..13624
                     /locus_tag="VYN12_001299"
     CDS             12965..13624
                     /locus_tag="VYN12_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1415683.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSKVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            complement(13676..14827)
                     /locus_tag="VYN12_001300"
     CDS             complement(13676..14827)
                     /locus_tag="VYN12_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1415684.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDNYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14842..15573)
                     /locus_tag="VYN12_001301"
     CDS             complement(14842..15573)
                     /locus_tag="VYN12_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415685.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHASYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            15802..15903
                     /locus_tag="VYN12_001302"
                     /pseudo
     CDS             15802..15903
                     /locus_tag="VYN12_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(15875..16651)
                     /locus_tag="VYN12_001303"
     CDS             complement(15875..16651)
                     /locus_tag="VYN12_001303"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1415686.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLANTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(16644..17867)
                     /gene="trpB"
                     /locus_tag="VYN12_001304"
     CDS             complement(16644..17867)
                     /gene="trpB"
                     /locus_tag="VYN12_001304"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1415687.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(17845..18444)
                     /locus_tag="VYN12_001305"
     CDS             complement(17845..18444)
                     /locus_tag="VYN12_001305"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1415688.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(18431..19198)
                     /gene="trpC"
                     /locus_tag="VYN12_001306"
     CDS             complement(18431..19198)
                     /gene="trpC"
                     /locus_tag="VYN12_001306"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1415689.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENRAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAEDVAQRIKELQIDKG"
     gene            complement(19195..20199)
                     /gene="trpD"
                     /locus_tag="VYN12_001307"
     CDS             complement(19195..20199)
                     /gene="trpD"
                     /locus_tag="VYN12_001307"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1415690.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(20210..20776)
                     /locus_tag="VYN12_001308"
     CDS             complement(20210..20776)
                     /locus_tag="VYN12_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1415691.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(20773..22134)
                     /gene="trpE"
                     /locus_tag="VYN12_001309"
     CDS             complement(20773..22134)
                     /gene="trpE"
                     /locus_tag="VYN12_001309"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1415692.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVINPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         7057 a         4845 c         3769 g         6931 t
ORIGIN      
        1 gaaattgatt ttttgatatt aaaataaaaa aggagggtag gcagtgttgt gatcaattat
       61 tgctggaggt cttattggtc tcttggcagg taaaatcact aaaaaagtag ttctatagga
      121 atcatcgcaa atgtattcgc tggtttagtc ggggcatatg caggacaatc tcttttaggt
      181 agttggggtc catcaatcgc tggaatggct ttgctcccat ctattgtagg tgcagcgatt
      241 gtgattactg tagtgtcatt ctttacaggt agaaagtaaa cttttcgcca gtaaagttag
      301 caaactattt ttaaatcaat gacgggaaaa atagtttaaa tgttaaatcg aaaggattgt
      361 atatgtcaaa agcaaagaaa atatgtttca ttattttctg tattttaatc ttgacaattt
      421 tccttcctgt tttgatagat tatcatcaag ttagtgatct aggtattcat ctacttagct
      481 ggagacagaa ctccgtagtt gaattctatc ttgctagata tgtcttttgg gggacagtgg
      541 ttctatcaac tttagtttta ttatccattt tagttgtgat gttttatcct aaacgttact
      601 tggaaatcca acttgaaact aaaaacgata cattaaaatt aaagaattcg gcaatcgaag
      661 gttttgttag aagtttggtg agtgatcata gattgatcaa gaacccaact gttcatgtaa
      721 atttacgaaa aaataaatgt ttcgttcatg tagaaggtaa aattcttcct tcagacaaca
      781 tcgctgacag atgccaaata attcaaaatg aaataactaa tggattgaag cagttttttg
      841 gtattgagcg tcaagtaaaa cttgaagttg cagtaaaaaa ttaccaacca aaacctcaaa
      901 acaaaaagac tgttagtcgt gtgaagtaag gaagtaaaaa atggaatggc ttaaacaata
      961 tcgatatcca attatcgctg gtctcatagg cgtatttctg gcttgtttga ttgtctcctt
     1021 tggcttcttc aaaacaatat ttgtattgat tttaggagca ctgggagttg cagctggatt
     1081 atatatcgaa aaaaactata tagataaata aaaaaataaa aattactaat ttaattaaag
     1141 gagtttcata tgtcaaacga aaaaaacaca aacactaacg tagaaaagaa agatgctact
     1201 gttgtagctc acgaaatcaa aggggaactt acttacgaag ataaagttat ccaaaaaatc
     1261 attggtcttt cactagaaaa cgtttcaggt cttttgggaa tcgatggtgg tttcttctca
     1321 aatcttaaag aaaaaatcgt taacagcgat gacgtaacaa gtggtgttaa cgtagaagtt
     1381 ggtaaaacac aagttgcagt tgacttaaac gttattgttg agtaccaaaa aaatgttcca
     1441 gctttatatt cagaaatcag agaaatcgta tcttcagaag ttgctaaaat gactgacttg
     1501 gaaattgttg aaatcaacgt aaacgttgtc gacatcaaaa ctaaagaaca gcatgaagca
     1561 gactcagtaa gccttcaaga tcgcgtatct gacgttgctg aatcaacagg agaattcact
     1621 tcagaacaat tcgaaaaagc taaatctggt cttggatctg gtttctcaac tgttcaagaa
     1681 aaagttagcg aaggtgtaga agctgttaaa ggtgcagcaa atggtgtagt atctcacgaa
     1741 aacactcgtg taaactaaga taaaataaat ataacaggag aaattatcat gtcagtagaa
     1801 gaaaaattaa atcaagctaa aggttctatt aaagaaggtg ttgggaaagc catcggtgat
     1861 gaaaaaatgg aaaaagaagg agcagctgaa aaagttgttt ctaaagtaaa agaagttgcc
     1921 gaagacgcta aagacgctgt agaaggtgct gtagaaggtg ttaaaaacat gttgagtggc
     1981 gacgataaat aaggttaaaa gttactttat ctttttggta acattagtca aaagagtctg
     2041 agtcaagatg attctcagaa aacaaaaagc tagagattcc caattgcgga actctagctt
     2101 tttaattttg cctctttctc ttattatatt tcagcaggtt gttggccatg agtatgaatc
     2161 ccatgtcaat tctcacttga cgcttacctc tcagatgaca tctcttataa cccaaacaaa
     2221 cctttatctg cccaaagaca gatttcatat caatcttacg tttagcgaaa atttgtctac
     2281 ccttggaaga taaaagtgcc tgatattctt tagtttttaa acactggtaa cgttcattca
     2341 tatacagtcc cttttgaggg gctgattcag gttcataatc gcagtcaaca ttgatttcaa
     2401 ggctgtttgc tttctatctc ccctttttca tgatatattt tcgtacaggt gcttcaatag
     2461 tttctatagt aaaatgaacc aaaaatagta cacgttgcgg tataatgttc ttgtggcata
     2521 ttcattagat tttcgtaaaa agttctctcc tatttgtgag cgaacaggta tagtcaattg
     2581 attgtcagtt tgaagaccaa gagtcgtaag gcaaaggata tagcagaatc catccaaggg
     2641 tggctggcac aatttctagt gaacctcttt aaatctatta cgtttgactg tggaaaagag
     2701 ttttcaaaat ggaaagatat ttccaatcat cacgatagtg agagcttttt tgcgaatcta
     2761 ggatgtccaa gacagcggtg tctcaacgaa cattcaaata gacttttaag gtgtcatgac
     2821 ttgccaaagc agacagattt caacgaagtc agtcaagaat tttaggctgg gtaaaaactc
     2881 aatttcagga gaaaatgaaa taaatattcc cacaataaaa tgcatagtat caaagttttt
     2941 ccaacacctg atattatgca ttttttaatt ttaaagactt tttcccagcc tcaagaaatc
     3001 acatcccacc taaatccttt ggataccaaa tacctcatca ggtattttct gagttggtaa
     3061 gactgtctag cttaatttga caaatggagg gcgttaaatc cagtttttac aggaaatcta
     3121 tttaaatatt ttcacactga ccttacaaaa tatgaaataa attatataaa gtcattccca
     3181 tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt aagacttttg
     3241 atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact ggaacaggtg
     3301 ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga gacagctggg
     3361 aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata gaaaaaaaca
     3421 ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta gaaatcaagc
     3481 ccaatagaag accacaaatc atatagaatc ctatcttatc aaattgataa gtttttttaa
     3541 aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt tgaacaatgg
     3601 atactagccg tactgataat tgagataaca aaacttgaaa aataagatga cctagaaatc
     3661 ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc tctttacttt
     3721 gtgaaaatct tttgattgtt gaaataatcg ccattataaa aacagagaaa ctagaataaa
     3781 aagcaatatc actgaccgaa tggtacccaa aactatccat aagtggctta attataattc
     3841 caccacccat gcctgatata gaacccaatc cactagctat tataatgatt agaaaataaa
     3901 taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac ctagatggct
     3961 actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat tacaataaga
     4021 acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta tcccatattt
     4081 tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg gattgcgaca
     4141 ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta aaaattcata
     4201 gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa atcttccttg
     4261 ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag gatattcaga
     4321 ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag acattccgct
     4381 ccaattacag aaagccaatg catcttctaa agcaacatga actactggat ggtcttctaa
     4441 acccactaga ttactattct caccgtaggg atgtttccag caaacgttcg gaacttgtaa
     4501 ccaccacgga gccccagcag aatgaggata tccctccctt tctgcctctg gaacgaacaa
     4561 tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg tttctttcac
     4621 aaattgagca aattcttgat tcgtaactgg agtattcgca atggaaaaat cctttacact
     4681 aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat ttgttcccat
     4741 cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc cgttttcgtt
     4801 agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac aacaaaacct
     4861 tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac aataggttgg
     4921 tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat atcaaataac
     4981 tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa gatatattga
     5041 ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc ctcgtactgt
     5101 ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt tcctcctgcc
     5161 aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat tgttccccta
     5221 ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat acttccctga
     5281 taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg atccgaaaca
     5341 aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa aaagcgacta
     5401 atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct tctttgatca
     5461 tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc taatacttcc
     5521 caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat atcaaaatag
     5581 tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag aaaaaaagga
     5641 accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca gtttgttgga
     5701 tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc cattccgtca
     5761 tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata gtcactagca
     5821 taatcaaatt gacttccata agccttatca tactttctat caacatgtag atacccatcg
     5881 tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg catcttacca
     5941 atacactctg tttgataacc catatcttta aagacttttg gaagagtatt agtaaaattc
     6001 caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa gccagtcaat
     6061 aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc aaaattataa
     6121 cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt actattcaag
     6181 gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg ctgttttgtc
     6241 tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata tctaccttta
     6301 ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg ttatgtttta
     6361 tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat tttctagtac
     6421 tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct ttgtctaata
     6481 acaattttag tggagataag aaatcctaca cctaactcat cttacacgta atctatttct
     6541 attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat atgccatttt
     6601 cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata agatgatggc
     6661 acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta cccaagtaac
     6721 gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta ccgttgccat
     6781 gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa ctggtaaacc
     6841 ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt tagcaacttt
     6901 tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta atcctccaaa
     6961 ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt cacctttttg
     7021 gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga tgggagccaa
     7081 tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga tcatcagaat
     7141 aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct tgtaaaccca
     7201 atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg ctactatata
     7261 catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag ggggaactga
     7321 atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa tagaggctaa
     7381 aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc ctggaatcac
     7441 attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa ttccttgtaa
     7501 gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg taactgtact
     7561 tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg tatcaacctt
     7621 gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa caattggtat
     7681 acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt tcgtaatact
     7741 ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca aagcaatgga
     7801 acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa ctaaaaactt
     7861 ctgattccca actttcattg caattggaga aagtttttct tgcattttat ccaacattgt
     7921 attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca cttctttcgc
     7981 caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca tcaagaggct
     8041 aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag ccttatgcgc
     8101 ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga aatccccttt
     8161 ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat acataattag
     8221 ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct tagtctaata
     8281 aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct gtcatcggaa
     8341 taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct ggtaaatagc
     8401 gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt tcttctgctt
     8461 caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct gccttttgca
     8521 tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata attgttactt
     8581 tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag atactgtatg
     8641 tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg ccagtccccc
     8701 atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc taagtgcaat
     8761 ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac tcaatacaag
     8821 accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat gaaaggctgg
     8881 aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca attgctctgc
     8941 gacagaaagc tctgccacag gctcattcac tcctgccccg tgcattttac cagctataat
     9001 caaacctgag aaattctctt tagcagattg aactgctttg ataatctctt gattgctaac
     9061 tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct ctattcgatt
     9121 caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct ctagcatctt
     9181 tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa gctggtgtaa
     9241 gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct caaaaacatc
     9301 aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag aattagttat
     9361 atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc taccttcact
     9421 tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag atggatttgc
     9481 actaattaaa cgtttcattc tcaatcctcc aataacttaa accgtttttc aatagctatt
     9541 acaaatggta aataaagtaa gacatccaaa acaatcaata caatttgtaa taatgaacca
     9601 gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca acctggatct
     9661 gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag taagttaaac
     9721 attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg aacgccaaac
     9781 attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc caaagttttt
     9841 agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac taaacctatg
     9901 gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt aaaaatattt
     9961 ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc taaccataac
    10021 ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca aaaactacta
    10081 ttaaggaaaa ttaagataag aaggccaata acattatttc ctaaaagtcc aagtggacct
    10141 cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc taaagttgca
    10201 taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact aaagctttta
    10261 gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt tataaaccat
    10321 tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc ttttgatgcc
    10381 atgaaagcgg taggcattcc tgctccagcc tctcctctaa tgaaaggcgt aactgtaata
    10441 aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg tctagccata
    10501 aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact atcaacaccc
    10561 ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc tggaatagga
    10621 aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt tagagtaata
    10681 ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac tggaagtaac
    10741 ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat tatcaaaagt
    10801 tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt gttatttata
    10861 ttttacaact ataagaaagc cttgtcaagg atttgtgtaa acatttgatt attttttatt
    10921 atcaatatat aataaaaaga gaccagtaag taatgaaaag cttaaaaaga ttaacatcta
    10981 catttatcca tagcaaaaaa tcataggatt ttaagaatct gacaactagg aagaaaacta
    11041 atatgacctt atctaagaaa caattacaac taagagctaa aatactggaa acagtttaca
    11101 cattaggtcc catttcacga attgaaatcg ctactaaaac aggaataaca cctgcaacaa
    11161 ctagcagtat cacaaatgat ctgattaaag aaaatattct cttagaactt ggtgaagacg
    11221 aacacgatac aagcgtaggg agaaaaaaaa tcctgctaga cattcaagct aaacgatttt
    11281 actacattgg ttgtgaacta tctgaaaaac atttcacttt tgctttagga gataatctag
    11341 gaaatatctt aaaggaagag aaagaaattg ttactaaaca gttaatccaa gaaaagggaa
    11401 atcaactcat taaccagaca ctaaagcaat tcttaaataa ctgctctgat tatgaaatag
    11461 aagcaattgg aatcgcgcta cctggtcgct atttagataa ttataaaata acaacaaaca
    11521 atcctttatg gcaacatatc gacttagaaa tgattcaatc ccactttgat aagcctttgt
    11581 ttttctctaa caatgttaac tgtatggcta taggtaaacg cctatttagt cgccaacaga
    11641 atgaccctaa ttttgcttat tttcattttg ctagaggtat gcactgttct tatatctacg
    11701 acggaaacat ttatgggaaa ggaaatctaa tgattggaga aatagggcat acagttgttt
    11761 catctgaggg agaagaatgt agctgcgggc gcaagggatg cttacaaact tttgctggag
    11821 aatcttggtt aatcaaaaaa tcaaaaattc tatatcatca atctccctat tctctacttc
    11881 ctagtttagt caaaaatgcc gatgatattg atatccaaat tattttaacc gcttatcaat
    11941 taggtgacac tggaataatc acacttatcc atcaagcctt actctatctt agtcaaacca
    12001 ttttaaatat cagtatgatg attgactctc aaaaaatcta cctacatagt cctttactaa
    12061 caaatcaaca catcatccaa aaactatata gtgaaatgaa ctacaaaccc aaactgctct
    12121 ataatcgcct acctgaagtc attattgaac cttacaatga ttttacagcc gcacactcag
    12181 ctattgcact ttgtttgtat catacaattc tacattctta attttctatt acatttaata
    12241 aataggctaa aaagagggag tatatcataa aaagcgaata aacctgtttt ctgaaaatca
    12301 gaattctgtt ttgttcgctt tctttatatt tggaattata ctcctatctc ccctttttca
    12361 taatgtataa taaaatgaaa taataacagg acgaatcgat cggaacagtc aaatcgattt
    12421 ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta tattttcgta
    12481 caggtgcttc aaccatttga acgatttcaa atccttcttt ttggtaaaga ttctgaactc
    12541 tttgatttgc ctcgaagaca tttagagaaa tactatctat atcttcattt tcaaaggcca
    12601 aactaacaaa tttccttaaa gcctggctac ctaagtcttg ctcctgtttc tgggggttga
    12661 taaaaaatct cccgatatga agattgctgt cttctagcct gattttctgg ataaatccca
    12721 caaactcttg ttcatcaaag attgaaaaga ctccttccaa ggcttgaagg gtcagtagaa
    12781 aaggaatcct tggtcccatc cattgttctt gaaaggattt gcctagggag ttggaccact
    12841 ggcatacaaa ttgagcgttt tctgtgctca ccttttcttc aaaacgaatt gtcatctttt
    12901 cctcaccacc ttatctatgt ttctccatta tactatttct cccatttttt acgaatagat
    12961 aagtatgatt gatttttatt tttttctcgt cgggagcatt ctagcttcct ttcttggttt
    13021 ggtcattgac cgttttccag agcaatccat tatcagttca gccagtcact gcgattcctg
    13081 tcagactcgc ttgcgtccct tagatttgat tccgattctc tcacaggtct tcaatcgctt
    13141 ttgctgtcgc tactgcaagg tccgctatcc tgtctggtat gccctctttg aactaggctt
    13201 aggactcctc tttctgcttt actcttggga attactttcc ttgagtaaag tcatcctaat
    13261 cactgctggt ttgaccttgg gcatctacga ctttcgccat caggaatatc ccttactggt
    13321 ctggatgact ttccacctaa tcctaatagc ttcctctggc tggaatctgg tcatggtctc
    13381 cttcctcata cttggaattt tggctcattt tatcgatatc cgcatgggtg caggggattt
    13441 ccttttttta gcttcttgcg ctctcgtctt tagcgtaacg gagttactga tcttgattca
    13501 gttcgcttct gcgacgggta tcctggcctt tctcctgcaa aagaaaaagg aaagacttcc
    13561 tttcgtgcct ttcctcttac ttgctgcttg tgtgattatt tttggtaagc tactgcttgt
    13621 ctgataaaat ccaatttctg ccatatatcc ttcatgaaat tatttcacag ttaaattata
    13681 aattatttct tttgtacaaa gggatgatgt tatcaaatcg atctgttctt ctatcttctt
    13741 gatactgatc aaaaaatttc atttcgactg aaaatatttc gcttataaac tgtaaacgaa
    13801 tactttgttt agacattata gtcgctagac tgactagatg attactcaaa acgacgtcca
    13861 gaatactctt tactttgctt ggttttttaa caaaaatttg atcatccaaa ggttcaatca
    13921 ttttgtaacc tttttgcgca atttgacgat aaaagtaaga atgttgcttt ggagtcaata
    13981 atcctaactt aaaagctcga tactctaaag cctgtatcga aacattcaaa tccgacttca
    14041 ataaaatata attatcagga ttgctgacac gcttgccaac cctctcttca aatttgacta
    14101 aaaactcttc ttttggcaat aaaaaacatg atgcaaaata atttgcttct tgctccaaac
    14161 gatcgccatc ttcattcata tctttatatt tatgtaaaag aatatgtcct agctcatgag
    14221 ctaagtcaaa atttcgacgt acagatgatt tattcgttcc caacacaata taaggtcttc
    14281 ccaattttga ccatgcgcta taagcatcag cttggccatt aattaatcgt tccacgatat
    14341 agatgcctga acgttctaat ttataaagca aatcatgatt atcttttgaa atacctaatt
    14401 tttccctggc ataaagagcc aattcctcaa tggattctcc cttatgataa gattcactca
    14461 ctacattact taggtcatga attgtaatat taggtataat tacaaaactt tcaaaataat
    14521 caatcaaact atctacctta tgtaaataca tagtttgaat atctattgtt ttccgtgttg
    14581 ctaggtctgc atttctaaag gcaattacag aagaatcaaa tcgaatgctc tcttcttcct
    14641 gttcaaaata agttaaatca acatgaaatt ggttggccaa atgcattttg gttgataatt
    14701 taggtttcgt ttcgttggac tcaaactgcc aaatggcttg ttccgttaaa ttaattctct
    14761 gagctaattc tgctctactt aaaccattta acagccgtaa ttctttcaat acccgaccat
    14821 taaacattta catactcctt actacttttg accttcttgt ttttctattc ttggaataat
    14881 ttcaaaatct tctgtttccg ataattctga aaaattagga atatcttgat atttagcttc
    14941 ttcgaaatgg tacgaacttg attgaatata ctcagacaaa tcttgaatca agtgtaactg
    15001 accagttcgt gcatcaggca taacaacatc tacagatata atattgtttt ctgagtccgc
    15061 ctcataagtt aaaatcataa atttttcgat attcgaattt ttagtagctt gttcaatttc
    15121 ttgaatcatt tcatcagaaa ctaactccat ctgaattgga aaggaatgac tatcttcatc
    15181 atttttgtag gaagcatgtt gattaagata aagtgtattc atctgagcat attcaaataa
    15241 gtagccactc ttattttttt gtaccaaagg aaattggttc gtaagtcgct tcttaccctt
    15301 tataattaac aatactttcc catatttttc tgtatttgtt tcaaattcta aatatcccca
    15361 agtctgtcct gctaattgta atttatactc aaacaaatct gctgatgcaa atgcagtatc
    15421 aatatgatta ggtcgcgtcc atgcataacc attcgacact atcattgtct ctcttttttc
    15481 tagacgttca tctacataat ctttttgccc tttcatcaaa gtatctacaa ttttttgtgc
    15541 ctcaagcgaa tcaaagagat cctgattcaa cataattctt cctcctccaa atacttttta
    15601 atgaattata tcattttctt aaagaaatta ctacaataat tagctttttc ttaaagttct
    15661 gtgtcagagt aatttagaaa attatatctt ctatagtaaa atcaattaaa aactgaacaa
    15721 atttattggg aaattcaaat cactttctta aaatatttta ggaaccgtag tgtaatattc
    15781 cagattcaat tcactataaa actagccttt ctcctgcaaa agaaaaagga aagacttcct
    15841 ttcgtgcctt tcctcttact tgctgcttgt gtgattattt ttggtaagct actgcttgtt
    15901 tgataaagtc ctgaatcggc tctccttggt ggagagcttt tactattttc gaaccgacga
    15961 taacaccatc tgacaccgca ttgaagcgtt ccagatcggc ttgactagat acaccaaaac
    16021 ctgtcaagac tgggatgtcg gccacttgat gaagttgcgc caagtgcttg tccaaatctg
    16081 cacggtaatt gcctgatttc cctgtcactc cattgatggc aacggcatag atgaatccct
    16141 ccgccccttc aatcaactct ttctggcgct caattcctgt ggtcaagctt actaaaggaa
    16201 tcaaggcgat atctgtattt gccaaaaatg gttctacaaa gttggcatgt tcatgaggca
    16261 ggtctgggat aatcaagccc ttcacagctg tatcagccag atctttgaca aagttctcca
    16321 caccgtactg aaagaggggg ttgaagtagg tcatgatgac cagtggaatc tctgtttcaa
    16381 tggttttcaa ggtttcaact aaagcctggg tagaggtccc gtgggctaaa ctgcgcaagc
    16441 cagcttcttc gataacaggt ccatctgcaa cagggtctga aaagggaata cccacttcaa
    16501 ttgcagagac acccaaatct tctaaaaagt ggattgtttc tcctagtcca tccaaacctt
    16561 tctcgtggtc accagccatg atatagggaa caaaaattcc ttttccagct gctttaatag
    16621 catttaattt ttctgttagt gtcttaggca tgagcttctc ccttctttgc tgcatctgct
    16681 tccaagcggt ccttgacttg aaccacatcc ttgtccccac gacctgatag gcagacaatc
    16741 atagactttt ctggtccaag ttctttggcc aatttcaccg caaaggcgat agcatggcta
    16801 gattccaagg ctgggataat cccttccaca cgagacaaga gttggaatcc ttccaaggct
    16861 tcttcgtctg tcacagggac atagctggca cgtttaatat cgtggtagtg agaatgctct
    16921 ggaccgatac caggatagtc caaacctgct gagatagaga aggcttcaag aatttgacca
    16981 tgggcatctt ggagcacatc catgagggaa ccgtgaagga cacctggacg acccttggtc
    17041 aaggtagctg cgtggtgctc tgtatccaca ccaagccctg ctgcttcagt tccatacata
    17101 gctactgact catcttctac aaagggatgg aagagcccga tagcattcga cccaccacca
    17161 acacaggcta ctagggcatc tggcagatct cgacctgtca agtcacggta ctgttgttta
    17221 gcctctcgac cgatgacact ttggaagtca cgaacgattt ctggaaatgg atgaggcccc
    17281 aaggcagaac caaggatata gtgggtatcg tcgatattag ccacccatga acgaagggct
    17341 gcattgaccg catccttgag cacgcgcgaa ccatctgtta cagcctcgac cttggctccc
    17401 aaaagctcca tgcggaagac attgagggct tggcgtttga catcttcctc acccatgtag
    17461 atggtacatt ccatgttaaa gagggccgca gcagttgcag ttgccacacc gtgctgacca
    17521 gcacccgttt ctgcgataat tttcttttta cccatgcgtt tggcaagcca aacttgtcct
    17581 aaggcattgt taatcttgtg ggctcctgta tggttaaggt cttcccgttt gagataaatc
    17641 ttggctccgc cgatatgctg ggtcaaattt tttgcgtagt aaaggggagt ttcacgtccc
    17701 acatactggc gcaaaagttg gtttaattcc tcttggaaac ttgggtctgc ctgactttca
    17761 cggtaggcct tctccaactc caaaactgct gtcatcaatg tttctgggac aaaacgtccg
    17821 ccaaattttc cgtaaaatcc atctttattt ggttcttgat atgccattct ttaccctctc
    17881 tataaatctt ctaatctttt catgatcttt ttgtccatct gtctccactc cgcttgatac
    17941 atctactgca tagggagtaa agtgttgaat tgcttttact acattatctt cattaaggcc
    18001 acctgcgata aagaagggct gtgctagtcc agtcgtatcc agttgacccc aatcaaaggg
    18061 ctggccactt cctgccacag gggcatcaaa gagtagataa tctgcctgag aattggggac
    18121 atgcccattt ccatctacct gcacagcctg aatactggca caaggcaaat tctcaaataa
    18181 atcatctgcc acctgaccgt gaacttgaac caagtccaag ccaactttgt caatcgcttc
    18241 cagcagttct acccgacttg gtgaaacaaa tactccaacc tttttcacat ctgcaggaat
    18301 aagctttgcc aacacagctg cctcttctaa agtcacctgt cttttactag gtgcaaagac
    18361 aaaaccgata tagtcggctc ctgctgaaac ggctgtttcc accgcttctt tggtcgatag
    18421 tccacaaatc ttaacctttg tcaatctgca actccttgat tctctgggcc acatcctctg
    18481 cctgcatgag agctgtccct actaaaattc cgttaaagta tggggctagt cgttccgcat
    18541 cctgccctgt gaaaatagca gattcagaaa tgtacaagca atcatctttg aaatgtttag
    18601 ccaagtctac actggtctgc aagtcgacct caaaggtggt caagttgcgg ttattgaccc
    18661 cgataatctg ggcaccaagt ctgtgagcca cttctagttc agctagattg tgagtttcca
    18721 ccaagacttc cagaccaagc actgtcgcgt agtcgtaaag ttccttaaga cgttcttctg
    18781 ccaaggctgc cacaatgagc aagatgactg tcgcacctgc attgcgagcg cggatgattt
    18841 gcttttcatc gatgataaag tccttgttga gcgtcggaat ctctacctga ctggaaatct
    18901 cccgtagata atccaaatgt cctttaaaga aaacttcatc tgtcaacacc gaaatcatca
    18961 ctgctctgtt ttcttcataa gtctgggcct gttgcacaat atccacatcg agattgatat
    19021 ctcccaaact agggctagct ttcttgacct cagcgattac ctgcaagcgg tcctgatgat
    19081 tcttcaaaaa ttctgccaag cgataggtct ggcgcagagg ctggatttgc tccagcttca
    19141 tctgctccac ctcacgcgcc ttctgctcta agattcgtgc taaaaattcc tgactcattt
    19201 ttggtactcc tgtaacagtc tgagtttttc aagggccttg cctctagcaa tcacttgacg
    19261 ggccaaggca actccttcct tgatgctatc aatcttacca ttagcataga aaccaagacc
    19321 agcattcaag actgtcgttt ccaagaatgg acttgcttcg tttttcagaa cgctaagcaa
    19381 aatttctgca ttttcctgag cattcccacc acgaatatct tccatagcat agccttccat
    19441 tcccaaatcc tctggagtaa agcttgacaa gctgatttcg ccattttcaa gaagtgcaat
    19501 cttggttgtt ccgttcaagc cagcttcatc caatccttct ggtccagcaa ccacgatggc
    19561 acgtttgcga cccatatttt tcaaaacctg agctgtactt tctaggagtt ctggacgact
    19621 aattccaaga agctgtgttt ctaaagccat tggatgaatc agtggaccag tcaagttcat
    19681 aatcgttgga attcccaatt ccaaacgagc tggcatgatg tatttcatag ctgggtgcat
    19741 atttttagcg aagagaaaga cgattccagt tttatcaaag accttaccta gttcagctgg
    19801 tttgaggtca agattgattc ccaaggcttc gaggacatct gcggaaccag atttagaaga
    19861 aatcgagcgg ttaccatgct tggccatgtg aataccgcca ccagccaaga caaaggctgc
    19921 agttgtggaa atattaaaac tgaaagactt gtccccacct gtaccacagt tgtccatggc
    19981 atcatgaatc tcagttggaa tatgctgggc atgtcctctc atgacttggg caatggctgt
    20041 gcgttcttca ggtgtttccc ccttcatctt aagagctaag aggagagaag caatctgcgc
    20101 ttcagttaca cgcccagtta cgatacgctc aatgacatcc gtcatttcca cacctgataa
    20161 attttcaaat tttgctagtt tttcaataat ctctttcatc ctagtttcct cactttacaa
    20221 ccttctcgat aaaattccga atagaagaca agccgtctgg cgttccaatg ctctctggat
    20281 ggtactggaa gccataaatc ggtaggtttt tatgttgaat ccccatgatg gcttggtcat
    20341 cagtcgaacg agctgtcact tcaaagtctt ctggcatttc ctcaatcaaa atactgtgat
    20401 aacgcatgac cgcacggcca tcctcaatac cttgatacaa aacagatggc gcttcaaagt
    20461 tgatattgct ctgtttccca tgcatgactt ttggagccaa acctagctta ccaccaaaga
    20521 cttctgcaat ggcttggtgg cccaaacaaa tccctagaat cggcttcttg cctgcaaaat
    20581 cacgaatcat gtcttccatc tttccagcat caactggcca accaggacca ggagaaaaga
    20641 ccagaccatc tgctttttca gcttcttcat acagcttgga atcatcattt ctcagaacct
    20701 gaacttctgc aaaattccca atgtattggg ccaagttata ggtaaaagaa tcatagttgt
    20761 caatcaataa aatcatggtc ttagttctcc aattctagtc atagattttg ctttgttaat
    20821 ggtttcttgg tattcgtttt gggcgataga gtcgtagaca atccctgccc cagcctgcac
    20881 ataggctctt tgatttttga gaatcatggt tcggatggca atggccaaat ccatatcacc
    20941 cgtcgcagac aagtagccga ttgctcctgc atatacgctc cgtttttccg tttccagttc
    21001 atagatgcgt ctcatagctc gaatttttgg tgctccagaa acggttccag caggaagcgt
    21061 tgctttcaag gcatccatgg cagtgagttc tgcaagcaaa cgtcccttga ccacactggt
    21121 caaatgcatg acgtagcgga agagctccac ctccatatac ttagtaactt ggacactggc
    21181 cgtttcagag atgcggccaa tatcgttacg ccccaagtct accaacattc gatgttctgc
    21241 tgtttccttc tcatcagaga ggaggtcagt cgccaaggcc ttgtcttctt catccgtagc
    21301 ccctcttggt cgcgtccctg caatcggatt ggttgtcacg atgccatttt tgacagaaac
    21361 caaactttct ggactagctc cgatgatttg ataatcccca aaatcataga aataaaggta
    21421 attagaagga ttaatcacgc ggagatttct gtagaagtca aatggatttc cagtaacttc
    21481 tgctgagaag cgctgactga gtacacattg gaacatatct ccgttacgaa tcaagtcgcg
    21541 agcggtttcc accatttcct caaacttctg aggagcgata tggggtttga agtctaacgg
    21601 agatagatcc aagtcttcaa attcatttgg agcaggaatg cgtaactcct caagcacttg
    21661 gttcaaggat ttttccaagg cctcttgact gcgctcacta taaagtgcat cctctatgac
    21721 atgtatcttc tccttcttgt ggtcaaagac catatagctc tcatagacaa agaaatgcat
    21781 gtctggcgtc ccaattgtat cctcagggat ttgaccaatt tcttcataaa gcgaaatcat
    21841 atcgtaaccc acaaaaccaa tggctccacc accaaaaggg agctctgagt ggtgctgact
    21901 cttatgaatc acttcataaa ggaaatccaa gggatcccga tcaatcactt gaccattttg
    21961 atagagaact ccattttcaa acttaatctc aaaaactgga ttataggcta ggatagaaaa
    22021 acgagctgtt tccttgtctc tcggaatact ctctaagata accttgtgtt gcccctttaa
    22081 gcgcatataa gccaagattg gtgataagac atctccatga atgattcgtt ccattgtaat
    22141 ttccctttca gttcgaattc tagttcgtag cgactgtatg aaaaatcccc acgcaaaata
    22201 acttgcgtga ggacgaaatt cgcggtgcca cctcaattat aggatttctc ctatctctca
    22261 ttcctgtctc agatatctcc tgtaacaggc tgtgcgataa agggcactcc cttgagaatg
    22321 atgttttctt ctctcgtttc agatgaaccc aactttacag ctttctctgc ttgttttcag
    22381 caaccacaag ctctctgtga gagaaagaac tgtaattttt ccatctatta ttttttagct
    22441 tctagtagtc tgcaatcgca gctaggtcct tccctccacg accagagaca ttgatgaaga
    22501 gatgttcatc tcggtacacc tttatactct tcgaaaatct cttcaaaccg cgtcaacgtc
    22561 gccttgccgt aggtatggtt actgacttcg tcagttctat ct
//
LOCUS       DAVLTG010000031        22587 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLTG010000031 DAVLTG010000000
VERSION     DAVLTG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.031"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(250..1857)
                     /locus_tag="VYN12_001310"
     CDS             complement(250..1857)
                     /locus_tag="VYN12_001310"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1415693.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2247..2834)
                     /locus_tag="VYN12_001311"
     CDS             complement(2247..2834)
                     /locus_tag="VYN12_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1415694.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2962..3411)
                     /locus_tag="VYN12_001312"
     CDS             complement(2962..3411)
                     /locus_tag="VYN12_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415695.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASSRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3416..3805)
                     /locus_tag="VYN12_001313"
     CDS             complement(3416..3805)
                     /locus_tag="VYN12_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1415696.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3833..4459)
                     /locus_tag="VYN12_001314"
     CDS             complement(3833..4459)
                     /locus_tag="VYN12_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1415697.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4473..5036)
                     /locus_tag="VYN12_001315"
     CDS             complement(4473..5036)
                     /locus_tag="VYN12_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1415698.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5201..5435)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5489..5992)
                     /locus_tag="VYN12_001316"
     CDS             complement(5489..5992)
                     /locus_tag="VYN12_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1415699.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6185..7015)
                     /locus_tag="VYN12_001317"
     CDS             complement(6185..7015)
                     /locus_tag="VYN12_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1415700.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7000..8682)
                     /locus_tag="VYN12_001318"
     CDS             complement(7000..8682)
                     /locus_tag="VYN12_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415701.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8784..9041)
                     /locus_tag="VYN12_001319"
     CDS             complement(8784..9041)
                     /locus_tag="VYN12_001319"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415702.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9048..9596)
                     /locus_tag="VYN12_001320"
     CDS             complement(9048..9596)
                     /locus_tag="VYN12_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1415703.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9611..10459)
                     /locus_tag="VYN12_001321"
     CDS             complement(9611..10459)
                     /locus_tag="VYN12_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1415704.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10648..11997
                     /gene="trkA"
                     /locus_tag="VYN12_001322"
     CDS             10648..11997
                     /gene="trkA"
                     /locus_tag="VYN12_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1415705.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12001..13440
                     /locus_tag="VYN12_001323"
     CDS             12001..13440
                     /locus_tag="VYN12_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1415706.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13565..13822)
                     /locus_tag="VYN12_001324"
     CDS             complement(13565..13822)
                     /locus_tag="VYN12_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEV1415707.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            14582..14752
                     /locus_tag="VYN12_001325"
     CDS             14582..14752
                     /locus_tag="VYN12_001325"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415708.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            15364..15648
                     /locus_tag="VYN12_001326"
     CDS             15364..15648
                     /locus_tag="VYN12_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415709.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            15641..15879
                     /locus_tag="VYN12_001327"
                     /pseudo
     CDS             15641..15879
                     /locus_tag="VYN12_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15975..16193
                     /locus_tag="VYN12_001328"
     CDS             15975..16193
                     /locus_tag="VYN12_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415710.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(16560..18884)
                     /gene="pflB"
                     /locus_tag="VYN12_001329"
     CDS             complement(16560..18884)
                     /gene="pflB"
                     /locus_tag="VYN12_001329"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1415711.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            19279..20340
                     /gene="dinB"
                     /locus_tag="VYN12_001330"
     CDS             19279..20340
                     /gene="dinB"
                     /locus_tag="VYN12_001330"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1415712.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLRIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWKELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVQSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(20487..21332)
                     /locus_tag="VYN12_001331"
     CDS             complement(20487..21332)
                     /locus_tag="VYN12_001331"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1415713.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            21588..22456
                     /locus_tag="VYN12_001332"
                     /pseudo
     CDS             21588..22456
                     /locus_tag="VYN12_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6890 a         4846 c         4183 g         6668 t
ORIGIN      
        1 tatttcaatt cactatacaa tccagttcct aaaactttgc tagaaattga tttggctttc
       61 cgaattaatt tgttcaaatt ttatttcatt tcaatatact gataaatcca ttcactagca
      121 cagggcaaga gggagtcgct attgatttca acggtagcag gtacatacag aggactccta
      181 cctcagatat actgcaatat catcgtatgc aaaaaacctc tgagattttt ctcaaaggtt
      241 ctgattttgc taattgctgt tctcaaccgc tgcagtaaca aaggcagtgt agagttcttc
      301 tggtcggttt ggacggcttg acagttcagg gtgatactga caagctacaa agaatttatt
      361 ttcaggaatt tccacgattt ctaccaaacg attgtctgga gaaactcctg aaaagacaaa
      421 acctgctgcc tcaaactgct cacggaaggc attattaaac tcataacggt gacggtgacg
      481 gcgttgcacc acttcttgat tgtgataagc agcagcagcc ttagagccac gtttcaactt
      541 agacggataa agtcccaaac gaagggttcc acccatatcc tcaatatcaa tctgatcacg
      601 catgatatca atgatagggt attttgtttc tggtgcaagc tctgcagaat tggcaccttc
      661 aagacctaaa acgtgacgag caaactcgat acatgtcaac tgcattccca agcagactcc
      721 caacattgga acatcatttt cacgcgcata gcggatggct tggattttcc cttctgtacc
      781 acgttgacca aaaccacctg gtacgatgat cccgtccgca tcagacaaga gttctgctac
      841 attctctgct gtcacatcat tggcattgac ccaattgatt ttaacttcta catcattgac
      901 atagccagag tgtttcaagg cttcgaccac tgagatatag gcatcttgca actccacata
      961 cttaccaaca agggaaatct taacttgttt cttgaggttc atgaccttgt ccaccatggc
     1021 tgaccattct gtcatatccg ctgctggtgc gtctaatttc aaatgatcac aaacaatttg
     1081 gtccatccct tgtgcctgca agttcagtgg aatttggtaa aggtgttcaa catccaacga
     1141 ttcgataacg gcttctggtg ccacatcaca gaactgggcc agtttatttt taattccttg
     1201 accagctggc tcttctgtac gaataaccaa catatttggt tggattccca agccacgcaa
     1261 ttctttgaca gagtgttggg ttggtttggt tttcatttca ccagcagcct tgaggtaagg
     1321 aagcaaggtt gtatggatat acatgacatt atccgcaccc acatctgcct tcatctgacg
     1381 aagagcctct aggaatggca aggactcgat atctcctact gttccaccaa cctctgtgat
     1441 aatgacatca gagtcggtcg ttagagcggc acgcttgatt ttttctttca aagcatctgt
     1501 gatatgagga atgacttgaa cagttgcccc aaggtattct ccacggcgtt ctttacgaag
     1561 aacttcactg taaattttcc cagttgtcac gttggaatat ttgttgagat tgatatcgat
     1621 gaaacgttca tagtgaccca agtccaaatc tgtctcagct ccgtcatctg tcacaaaaac
     1681 ttccccgtgc tggtaaggac tcatggttcc cggatcaata ttgatataag ggtcaaactt
     1741 ttgaatggtt actttgagac cacgattttt caagagacgg cctagactcg ctgccacaat
     1801 ccctttccca atggacgata ccacaccacc agttacaaaa atatatttcg tagacataga
     1861 ttcctctttc taaaatgctc aaggtcttgt taactacgag gggatataga aaacaagacc
     1921 ctactaataa gaataatctg ggacgactgc accagattca caactaatac tcttcgaaaa
     1981 tctcttcaaa ccgcgtcaac gtcgccttgc cgtagatatg tgttcctgac tttgtcagtc
     2041 ttatctacaa cctcaaaaca gtgttttgaa cagcctacgg ctagtttcct agcttgctct
     2101 ttgattttca ttgagtataa aatacaagaa gataacttct tgaaaaaaca aaaatagctc
     2161 cctaagaact agggagcccc gacctctaaa agaggtgccc aaacaatatg atacctaaaa
     2221 ataggataat tgtcaatagc taactcttat tcctcgctgg tttcagcgtc gtcatctgaa
     2281 aactcgtcgt cgtcttcgtt gagatccaca tcttctccca agtcatctgg agcgatttcg
     2341 ttgatttctg catcataagc ttccacttca tttttttcat catctggatt ttcatcatcg
     2401 tatgaaagag ctggatctgc ttcgtatgca tcttcgtctt ctggatcatc tgcattgtag
     2461 tcaatggcat ctgaatcacc atccataaag gcattgacac gttttttctt agcttttggt
     2521 gctacttcat cgtcgtcatt ttcttcaaga gcgatgattt cttcgtcgat ttcgtccaca
     2581 ccataccatg aacgaagacc ccatttgttg tccccaagtg agatgaagct accgtcaaag
     2641 ttcaactctg tgtagaacaa aggcaaagct tcgcggatat cgctgtttga tgttccaagg
     2701 tagttttgaa tttcgtttac aagatcgcta aaatgcatct catgatcgcg accacgaagt
     2761 tccaagatag cacgcgctac ctcaatcata gatagttcac ttttttcttg cccagcaaat
     2821 acttctaatt ccaaagcgtt tctcctcatt tatactacta tcgccagagc gaacagactc
     2881 tgacctcatt ttatcattta ctctttattt tacgataatt ttgcggaata gtcaaaggtt
     2941 aagggggaga aagtggcagg attagactaa ttccaatata aaactccttc ctttttctgt
     3001 tgctccattt tccacaaatc caagcgactt gaaacaccta ctagaagcat gattgtaggt
     3061 gtagatttcc ttgactctca attctttcca tccttttact cgagccaatt caatcaaagc
     3121 acttagaatc ttttttccaa gtcctcgatg ttggtaagcg gaattcccaa tcacaatggg
     3181 gagattatcc tgagatagtg taatatcccc aattggaaac cattctccct tctccttgac
     3241 ttcaatccaa aaaagctcac catgccgatc caaataggaa tacatggctt ccaaggtcgc
     3301 ttgactgtaa ggaagcttca ccccatctac gaggtaaacc aagttcacat cctgatacca
     3361 agcaaaagct tcctcacaat aattgacctt ataataagga acaaaacaca atgcactacc
     3421 ttttcaacaa aagagttgct gcttgattaa aaccatcaca ccagttatac cattttgctt
     3481 catacccatc ttgagctagg atacgatctt ctaaatcaaa aacagagtaa atctttcttt
     3541 cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta tcccactcag
     3601 cagaaatcgt atcccgacct gccaataaag cctgataagc cctgtgatgc ccatctgtaa
     3661 tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggatt gtttctgccg
     3721 actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt tgagtcggat
     3781 gaagatctgc tatattgact ttcatttctt tctcctcaag ggaattcgat actcacttct
     3841 gtttgccttt aaatcgccat tggaagcgga gcttatcata aaagggaaac tcgataaaca
     3901 gggctcccaa gcccacacag agactggcaa gaacatctga tgggtaatga actcccagat
     3961 agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt acgatttttc
     4021 tccagacctg atctttaatc cgctgactaa gaataacaat caaagtccct accatcagcg
     4081 ttacagccag agaatgccca cttgggaagg aaaatccctt ctcctccacc agatgtaaga
     4141 tagctggtcg tgggcgctgg tagatatttt taaaggtcac gattaaaaga cctgccaaag
     4201 ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa aagacaaaag
     4261 ctataatgac aacccaagtg ataatcactg gaatatcaat cagacgtgtg agggatcgaa
     4321 aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc gattggtcaa
     4381 aattgaccaa catttcaggg taaaatttga ccatatagcc aagaataacg aaaagtaaaa
     4441 gggcaaaact gcccttcatt aaaaatgttt gtttatcttt catagtgttt taaggttggt
     4501 ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga ttacaccctc aatcaagtta
     4561 aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc aatatcaaag
     4621 ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa catggccaag
     4681 gttaaaccaa cagttccagc tagagagcct agtaggaaac gaagggttgt ccgttccttt
     4741 ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt catcggcaaa
     4801 ccaatgtaag tattcactcc ttggctgtta agaagcaatt tcaatagtga gcgaagcaag
     4861 agcactccta gagcagcagg caaatccatg accaccagac ccacaaggac tggcaagata
     4921 ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaagtcaaa gtacatcagc
     4981 acaaatgaga tggctgataa aattgcaatg gtcgaaagtc gacgtgtgtt tgtcataaca
     5041 ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct atctattctc
     5101 actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag caagtggtta
     5161 caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc tcccatccag
     5221 actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac ttctttaaag
     5281 agaaggaaat agagattttt cttttagact aggcgacaag ctgtaggcat aacttctggt
     5341 taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt aaagtcaccg
     5401 ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa acgcttgcaa
     5461 gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca taggtatgga
     5521 cgagctcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc atgcagacgg
     5581 tattagacac attgagactg cggacatgtt catcattcat gggaatacgg agagccttct
     5641 caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca aagagaaaat
     5701 aatggtcctc gtcagtcgat aaatccacct cagaatagac tttttccgcg aatttcgaaa
     5761 tcagatagag ttttcccttc atctgagata tgaaatcttc caaactctcg taaaaataaa
     5821 tctctagttt atcccagtaa tccaatccag cccgcttcat cttgcggtca tcaataggaa
     5881 agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta cgcgcgatat
     5941 tgcccgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc atgacttgct
     6001 tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag caaacagcgt
     6061 ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg aaactacttt
     6121 cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt tcaatttttt
     6181 caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt agtaaactaa
     6241 ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc aaggcctgat
     6301 aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg gcagtcgcaa
     6361 tagtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc agattgcctt
     6421 tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc tcctgagaca
     6481 tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc aggctgacag
     6541 aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac tgactaggat
     6601 gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta atggccaaat
     6661 ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc tgccaaatca
     6721 cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag accatcaaaa
     6781 cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct ttaaagcgaa
     6841 tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc attctggtgt
     6901 catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc ccagctcctg
     6961 acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct tgcatccctc
     7021 tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt tcttagccaa
     7081 gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat cgctcaacag
     7141 actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga cccggtctga
     7201 ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc ctttttgatg
     7261 taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac ctgcagtcgg
     7321 ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg tgacacgttt
     7381 tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa gtccacagat
     7441 tttcaaggtt tcatagactc tcgtttcaat ttccttctca tccacacctc gcaaacggag
     7501 ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag gattttgtag
     7561 cacatagcct actcgttccg cccgctctgc aacagaatcg ccttttatat cctgtttttc
     7621 ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta gagttgattt
     7681 ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat ctaaatgtag
     7741 ggattttaaa atcggtctat catcataaga aaaagatact tcctctagtc taaagagtga
     7801 ctgcaatgct ggggtttctt ttaccagttc cgtctgtaac tggacttgcc cttttgagat
     7861 agacaagtta tccagatctg ctaattgttc ttccttgact aagtccacac ctaattgacg
     7921 gagagtcgtt agataaaggg gttctcgaat tccattttga gtcaataaat cagtcgcaag
     7981 caactggtca gggctcccat taaaaaggat acgaccatcg tttatcaaga caatccgatc
     8041 cacagggcga tgcagaacgt cctccaaacg gtgctcgata atcagagtcg tcgtcccctc
     8101 ttccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg gatctagatt
     8161 ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac cagccagact
     8221 gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc tgatccagta aaggaagaag
     8281 gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg ctgtcacatc
     8341 attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact gcccatctgt
     8401 atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat caaaggctgt
     8461 ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg gaataatccc
     8521 attcaaacac tgacccaagg tagatttacc tgatccagat ggtccaacaa ttaagacttt
     8581 ttctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt gtgtttcata
     8641 ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct cttcattcgc
     8701 ttcttagact tctattttat cataaatcaa gcccttcttg cagtctcttc tcttaaaatc
     8761 ttagcgccaa aaagattcct atcttagctt acttgcctaa ctaatctata aacatcgaaa
     8821 aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc ttcaaaccac
     8881 gtcagcttcg ccttgccgta ggtatggtta ctgacttcgt cagtttcatc tacaacctca
     8941 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa tctcaaaaca ctgttttgag
     9001 caacctgcgg ctaacttcct agtttgctct ttgattttca ttgagtatta gtcctttttc
     9061 aaacttcctg cacgagtttg agttcctgca taggcaagta agagaagagt tcctgcaata
     9121 gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac tttttctgcc
     9181 gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac aagggcattt
     9241 gcaagtagtt gaatgaggtt aaaaataaga atatctttcc agtcaaaaac accattgatc
     9301 actcgaacgt actttctaaa aagtcccaca actaaaccaa agagtccgct agcgataatc
     9361 caagtccacc atagaccata accagcaaga gagtccttga ttgcatgacc aatcaacccg
     9421 acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac cgcatactga
     9481 agctggatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat gacgacaaag
     9541 agggcagcgc caattccgac agcaacaact tgtttaattg taaatttgat ttccatacta
     9601 ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa ccgacaccta
     9661 cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga tagagagagt
     9721 tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca tagacaacct
     9781 gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga tcaccaaatt
     9841 ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa ccgaaacgca
     9901 catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc gctacgactg
     9961 gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa gtaatgtgac
    10021 cactggccag tttagcacca gtataggcat agacatcacg accgtggaag gtataagaat
    10081 gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct acaatgccaa
    10141 cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat tgattttttg
    10201 cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca accgatacaa
    10261 acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc ccctcgaaaa
    10321 tattataagg cgtgatatcg tgcgtcaagt gatggatttt taaggttgga gactcttcta
    10381 aagccactcc aatcatagcc gataccgcac catcaaccaa accaaagtct gattgtaata
    10441 ccagtaaatt attattcatt ttatctcctt gtatatcctt tatcatacca tatttcagag
    10501 aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata gcaaatttcc
    10561 tactaaaagt tcttgttatt agctagtagg tgcatttttt cttgaaaaag ggtatgatag
    10621 ttacatcatg aaaaagtagg ttttattatg aaaattatcc ttgtcggagg gggaaaagtt
    10681 ggttttgccc tctgtcgctc cttggttgca gaaaagcatg atgttttgct gattgagcaa
    10741 gacgaagctg ttctcaatca tattgtcagt cgctttgata tcattggtat ccttggtaac
    10801 ggggccgatt ttgccattct tgagcaagcc agcgtccaag attgtgatat ctttatcgcc
    10861 ctgactgagc acgatgaagt caacatgatt gcagcagttc tagccaagaa aatgggagct
    10921 aaagaaacta tcgttcgggt gcggaaccct gaatattcta actcttattt caaggaaaaa
    10981 aatattctcg gtttttctct tatcgttaat cctgagctct tggctgcccg cgctatcgcg
    11041 aatatcattg acttccccaa cgccctgtct gtcgaacgct ttgctggtgg acgcgttagc
    11101 ctcatggaat ttgtcgtcaa gtccaccagc ggtctttgcc aaatgcccat ttctgatttt
    11161 cgtaaaaaat ttggtaatgt cattgtctgt gcgatagaga gggatcatca aattatcatt
    11221 ccaagcggtg acatgactgt acaggataaa gatagaatct ttgtcactgg taaccgtgtc
    11281 gatatgatac tcttccataa ttattttaaa tcacgcgccg tgaagagcct tctcatcgtt
    11341 ggggcaggta gaattgccta ttatctactt ggtattctca aagatagtcg tatcgataca
    11401 aaagtcattg aaatcaatcc tgaaatcgcc agcttcttta gcgagaaatt cccaaatctc
    11461 tacatcgttc aaggagatgg aaccgcaaaa gatatcctgc tggaagaaag tgctcaacac
    11521 tatgatgccg ttgcgactct aacaggagtc gatgaggaaa atctgattac ttcgatgttc
    11581 cttgacaggg taggtgtaca gaaaaatatt accaaggtca atcgtaccag tctcctcgaa
    11641 attatcaatg cgcctgattt ttcaagtatc atcacaccta aaagtattgc cgtggacacg
    11701 attatgcact ttattcgtgg tcgtgttaat gcccagtatt cagaccttca ggccatgcac
    11761 catctagcca atggtcaaat cgaaaccctg caattccata tcaaggaagc caataaaatg
    11821 actgccaaac ctctttctca actgaaatta aaaaaaggtg ttcttattgc agccatcatt
    11881 cgaaagggca agactatttt ccctactggg gaggatatgt tggaagtcgg agacaagctc
    11941 ctagtaacaa ccttgttgcc aaacatcacc aagatttatg acttgatcgc gaggtaagaa
    12001 atgaataaaa gtatgattcg ttacctcctt tcaaaattac ttttgattga agctgttctt
    12061 cttttggttc ctgttgcgat tgctgtctat taccgtgaat cgagccaagt ctttacagcc
    12121 ctcttttcga ccatagggat tctcgtattg ttaggcggtt cagggagttt acagaagcca
    12181 aaaaatcaac ggatttatgc caaggaggga gtcttgatcg ttgccctctg ttggatcctt
    12241 tggtctttct ttggtggtct cccctttgtc ttttctgggc aaatccctag ccttattgat
    12301 gccttttttg aaattagttc tgggtttaca actactggag caagtatttt gaacgacgtt
    12361 tcggttctca gccgttccct cctcttctgg cgaagtttta cccacttgat tggagggatg
    12421 ggagtgcttg tttttgcact tgctattatg gacaatgcca aaaatagcca cctagaggtg
    12481 atgaaggctg aggttccagg tcctgttttt ggcaaggttg tatccaaact aaaaaacact
    12541 gcccagattc tctatctcct ttatctagct ctcttctccc tctttgtcat catctattat
    12601 ctagctggta tgcctctcta cgatagtttt gtcattgcta tggggacagc gggaactgga
    12661 ggctttaccg tctataacga cggaattgcc cactatggca gctcactgat tacctatctg
    12721 gtcagtatcg gagttctggt ttttggggta aatttcaacc tctactacta cctcatgctc
    12781 cgtcgcatca aggccttctt tggtgacgaa gaacttcggg cttacttggt cattgtactg
    12841 gtttctacag gcttgattag cctcaacacc ctctacctct acccagggtt ttcaaagagc
    12901 tttgaaatga ccttcttcca ggtttccaac atcattacaa caactggttt tggatatgga
    12961 gatattacca actggcccct cttctcccag tttatcctcc ttttcctcat ggcaatcggt
    13021 ggctctgctg gatcaactgc aggtggactc aagattattc gaggcctcat cctttcaaaa
    13081 attgccaaaa accaaatttt gtcaatccta tcgccccacc gtgttttgac tctccatgtg
    13141 aatcaaacgg tgattgataa agatacccag cataagattc tcaagtactt tgtcatctat
    13201 gctatgattt tgctagcgct tatctttatt gtcagcctag atagcaatga ttttctggtc
    13261 gtgaccagcg ctgtctttag ctgtttcaat aatatcgggc ctattctagg aaccacttct
    13321 agtttctcaa tctttagtcc catctcaaaa attctcctct cctttgcaat gattgcaggg
    13381 cgcttggaga tttacccaat cctccttctc tttatgaaaa gaacttggtc taagagataa
    13441 aatacaaaat ccctcttttt acaattgtga aagagggatt tttatattaa aaagggggaa
    13501 cgtttttaaa tccaagcctg tctgtaagca aagttcttac tcaaataaaa gatggaaaaa
    13561 cttactacac agcttggtaa tgctccaata caaattgtaa ggctttactt ggattctttg
    13621 ttaaatgaat atattccatt cctctggtag caactatctg aatacctaat ctttctgcat
    13681 ccaccttcat ctctctataa taactccgaa cttgtggagc cagaataatt aaatcataaa
    13741 cacccataat atcataatga gctccgtacg ctcctgaatt cgcaatcact ctaacttctg
    13801 ctaattgagc gccctcgtta attgcattgg ctaattacgc acttgttcca gaccctgcac
    13861 aaagaaccag tactttcaac tccttacttt ttattacatc tatctcacca ggcattattt
    13921 cacttgtatc ctcctctaaa ataatatcat ttgagcttgc aatatctaca acctgtagta
    13981 gatatctcgt atttagacaa tatgaaaaca agacgacttc catataggaa accgccttct
    14041 ctctatgttg agtgatttat attaaaataa cttttcttct agctgcattt tattattata
    14101 aaaacattca tcataaccct gaacttaaat aacgattttt attcaagata catactccta
    14161 gaataaactt tatatgaaat tctcattttt gtttttacaa ttctccttag ttaaatcttg
    14221 tttaatatat gttttacata tagtatttag cgccacatag tactgaactc tctccaaaaa
    14281 cggttattcc tctttgaata gggcgttatc acaagaaaag catctccacg tttcaacttc
    14341 atatggctca aaaacaatca attgatgcta aaacctgtac ctagatgttt cggttcataa
    14401 aaccatgaaa ctgtaaaagt ggatgaaatt gatagcgata gtcaaatcaa gaggcatcat
    14461 aactctaaaa agtcacaata tataagttca tcctcggaaa aatatcattc taattgttga
    14521 aatgcctaca tgaaaagaaa cgtcaaatgc tcatgaaaca acgaatacag gtatcaaaac
    14581 tatgacaaaa caagtcccta aatttactaa agacactgct caactttaca cctgtaaatg
    14641 gttgttgtat aataaagtta caaagatgta cgaccacact gttgtaaatc atagtgttcg
    14701 cgaatatatt actgatagca tttctacaaa tacaattgaa gagactggat agactttaaa
    14761 cgaaatatgt cagtgttttg gcattcctag ccttcatatc atttaaagaa ttctatagac
    14821 aaaatttttc ccaatacaga cactcgtaac aactgcttca tttttctacc aacatattta
    14881 ggaacaggat aagatacaag aggattaatc catagatcag ttctatacca atctaagaca
    14941 aataagctaa aaaaacgatt gataataagc aaatagattc caaattttct ctatctgctc
    15001 attttaataa acaatactag tgtaactatc cttccagtca gaagcttgtc aaatcacacc
    15061 gaaaattctt ctaaaattta tctcgttagg caatcaagca aaaactcgac gatagtacaa
    15121 acattatcat acagaattga cttcctaaat tatatacttt agtaaggttt tcgtataaga
    15181 aaaaagattc attttacatt tctaaacatt cttttctaag atgaaaaaca gaatttttcg
    15241 attgtgattt aaagcaacaa gaagattttc agtatcatcc tatagatacg agctaattaa
    15301 gaaaaactac attttcgaat ataaactaca ataatataaa ctaaatttta taggaggaag
    15361 acaatggatt ggtacgatta tatgatacag gcatccaaac aatcacaatt caacgcaagc
    15421 cattggtttc gctatttgcg aaaagttatt tttgaagact attcttattt aacaaaccaa
    15481 gatgtagaaa agttgctaga ctccaaagaa ctaacccgtt ttcaaaaaat tagcttgaag
    15541 tatgcctttc aagagcatac tccaactcat aaatatgtga tttcattaaa taaacctgct
    15601 aagttaacca atgttcaaaa attgatggag aaatacaaac atggataaaa tgaaaccggt
    15661 cttccaagcc ctaaataaga aattaattca ggaaaatctg actttaacaa ttatggttat
    15721 gtcttagaat atcatggttt acgtgccaca caagatgttg atgcttttta tgaccaaaat
    15781 cagaaaatca atgaaattat tgctcgtgta ggaaaacagt ttaatcttaa catccacgaa
    15841 gagttatggc tcaacaatca tgttgcaaag caaatatgaa caaacaacct cccttaagtt
    15901 tatgcgaatc cttgtactca tttgagaatc tgaccgtttt agtagtccct attgagtatg
    15961 tgttaggaat gaagatgatg agtatcagag agcaggattt gaaagatatt ggtgcaatta
    16021 ttaaatacaa aaactttcat tcaccattcg atacctttaa atatttaaaa gacatgggat
    16081 ttgatactat tgacctctct gttctattag aaggttttag ttatgcttat ggtatggatt
    16141 ggttagaaaa attttttaaa gaaaatcaag ataaacttcg cgaattttat taacagtatc
    16201 aaacaagatg attgtcaatt agccagtcgt cttattttta tgatggaatg aaataaaatc
    16261 ggaacaaatc acttagagaa ttccagtcaa tttctagcgc tgtttgagac gtttcagtgg
    16321 actatagtaa aatgaaataa gaataggaca aatcgatcag gacagtcaaa tcgatttcta
    16381 agaatgtttt agaagtaaag gtgtactatt ctagtttcaa tctattatat ttcagattcg
    16441 gtccactatt ccttcccaaa aacattgcat attgcgccga aggaattgct cacactatcc
    16501 caagcacaaa accctcagtc gtttgaccga gggttccttt ttattattca agaacttgat
    16561 tagctcaatg catccaaggc gtcatccatt gaaagaactt cgtggaagac acgttgtgtc
    16621 aattcagttt tttgttctgg agtgaggtat ttagtgttta cacagtatcc agagatacgt
    16681 acgataacgt cttcgcctga catgattttt tcgtaaacat cgttcaagtc cataacgttc
    16741 aagttaacgt gttgtccacc gttttcgaag taaccatcaa ggattgttac caagttatca
    16801 acttgttcat cacgagtctt accaagagca cgaggtgata cttgtgtagt caatgagata
    16861 ccgtcagctg cataactaaa gtcaaggcta gaaagtgagt tcaagttttg caaccaacca
    16921 cctttagctt tgttagatgg gttagcacct ggtgagaaga attcaagttt agacaagttc
    16981 acagaaccat cttcgttgag gtatacacct ttgtgaactg gtgagttacc agtttgttta
    17041 gagtaagcaa cgttagatgt gattgtcaaa agtgatactg tagcttctgc gtctttgtat
    17101 agtttgtggc tacgtagacg agttgtgtaa gcttcgatca accattctgc caattcgttt
    17161 gaacgtgggt catcttcacc ccagcgtggg tagtcaccga ttgtttcgta atcgtagatg
    17221 tagccatctt cgtcacggat tggtttaact gtagcgtatt tgatagctga caatgtatca
    17281 acagtgttag caaatccaca gataccgaat cccatgttgg cacgttgttt agttggcaag
    17341 aaggccattt gaacagcttc gtagttgtac ctatcagtca tgtagtggat gatgttcaag
    17401 gcatctacgt aagtgtcagt caaccagtca agagattttt caaagttcgc tttaactgat
    17461 tcgaattcaa gaacttcgtc acggattggt tcgatatcaa atactttgta gtctttgtga
    17521 acatcgtcgt aaccaccatt caaaccagta agaagggctt taagaacgtt tacacgagca
    17581 ccgaagtact ggatgttgtg gcgttgttct tcattttctg gatcaagtgg agacacacag
    17641 catgagatac agctcatttc accatatccg tctttagcca ttgttgttac accttcgtat
    17701 tggatagaag agtgtttgtg gctcatgtgc atacagtagc gacggaagtt gtatggcaat
    17761 ttgtcagtcc aaagaactgt caagtttggt tctggtgagt taccgatgtt gtcaagagtg
    17821 ttcaagaaac ggtagtccat cttagtaaca cggtgacgac cgtcgttacc cataccagcc
    17881 atagaagttg tgataaaggt tgggtcacct gagtacaatt ggtcataagc ttttgtacga
    17941 gcaaatttaa ctgtacgaag tttcataacg aaatcatcaa cgaattcttg gatttctgat
    18001 tcagtaaatg taccacgagc aaggtcacgt tctgcaaaga tgtccaatac gattggtaca
    18061 cgacctagag atgtagcagc accgttaatc acacggcaga cagccatgaa agcaatgtta
    18121 acccattgga ttgcttcttt cacgttcatc gctggtttgc gaacatcaac cccgtaaagg
    18181 tcacccaggc gaacaacttg ttgcaatgct tggtattgaa ggtttacttc ttcacgaaga
    18241 cggattgttt cttcatcgat ttctttgatt gcattccagt cgtttacttt ttcttgcatc
    18301 aagtagtctg caccgtaaag agcaagacgt gcgtaaacac cgatgatacg tccgcgtgag
    18361 tatgcatctg gaagaccagt tacagtgtgt gcgtgacgag cgcgacgaat atttgaagtg
    18421 taggcacgga aaataccgtc gttaactgtt gttacatatt tagtgaagat ttcgtgaaca
    18481 gctgggtctg gttcgtatcc attttctttc aaagtagttt cagccatacg gataccacct
    18541 tttggcatga agttcaattt gaagagttca tcgttttgga taccgaagat aacttcattt
    18601 tctttgtcga taaatccagc agggatatca gcgatagatg ttggacgagt gtccattggg
    18661 aaacgagttt cttcgtagtg tgctttagtt tcttctacaa ttttcttgat gtgaagtgaa
    18721 cgctctgttg gtcctgcaag gaagctttcg tctccatcat aaggtgtgta gttagcttgt
    18781 acaaagcgtg atacacttgc tttttctttc caatctacgc ctttgaagcc ttcccaagct
    18841 ttgtcaaaaa tatcttgtgc ttcaacaact gtcttaacaa ccatattaat gtcctctttt
    18901 ttctagtaac agtcatctgt tacattcatg agacaagtat accataaagt aaccgatttc
    18961 aacaagtgaa aaattcctat ttttacactt tcttttctaa aacagtctat attttatttc
    19021 aaactgtatt atatttttga aaaaaataaa gtcctttttt ctttttttca gaaaaaaggg
    19081 tataataaaa gaaaataagc agttacactc aatggaaatc gaaaagcaaa ctaggaaact
    19141 agccgcaggc tgctcaaagc actgctttga ggttgtaaat agaactgacg aagtcagctc
    19201 aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagagat tttcgaagag
    19261 tataaaaagg tgctaggcat gttgattttt cctttgttaa atgatttgtc aagaaaaatc
    19321 atccatattg acatggatgc cttttttgct gcagtggaaa tcagggataa tcctaaactc
    19381 agaggaaaac ctgtcattat tggaagcgac cctcggcaaa caggtggacg gggagtcgtt
    19441 tctacctgta gttatgaggc aagagctttt ggtgtccatt ctgccatgag ttccaaggaa
    19501 gcttatgaac gttgtcccca ggctgtcttt atctcaggga attatgagaa atacaagtct
    19561 gtgggactcc ggattcgagc tatttttaag cgctatacag atttgattga acccatgagc
    19621 attgacgaag cctatttgga tgtgacagaa aataaactcg gtatcaagtc agcggtcaaa
    19681 attgctcgcc tcattcaaaa agatatctgg aaagaactcc atctaactgc ttccgcaggc
    19741 gtttcttaca acaaattctt agctaaaatg gcgagtgatt atcaaaaacc acatggtttg
    19801 acagtgattc tacctgaaca ggctgaggat tttctcaaac aaatggatat ttccaaattt
    19861 catggagtag gaaaaaagac agtagaacgt cttcatcaaa tgggcgtttt tactggtgct
    19921 gatttacttg aagttcctga ggtaacccta atagaccgtt ttggtagact aggctatgat
    19981 ctgtatcgaa aggctcgtgg cattcacaac tctccagtcc aatccaatcg catccgtaaa
    20041 tcaatcggca aggagaaaac ctacgggaag attctccgtg ccgaggaaga tatcaaaaaa
    20101 gagctgactc ttctatcaga aaaagtcgct ctcaatctac atcaacaaga aaaagctgga
    20161 aaaattgtca ttttgaaaat ccgctacgag gacttttcaa ctcttaccaa acgaaaaagt
    20221 cttgctcaaa aaacacaaga tgctagtcag ataagccaaa tagccctgca actctatgaa
    20281 gaattaagca agaaagaaag aggtgtccgc ctattgggga ttaccatgac tggattttaa
    20341 agctcaatga aaatcaaaga gcaaactagg aggctagccg caggctgctc aaaacactgt
    20401 tttgaggttg cagataaagc tgacgcggtt tgaagagatt ttcgaagagt ataaaacctt
    20461 gaagagttgc cccttcaagg tttttcttat acaaataaac ggacaaaact gtaaagtagc
    20521 aaaacactac caagcacgat acggtattta ccaaaaaggg tgaagtcgtg ttttttcaca
    20581 tagctggtca agaagcgaat agccaccatg ctgaccgcaa aagctactcc catcgcgacc
    20641 aagagtaaaa acaattgccc aaagctcaag agttctccgg ctttcacaaa tttgaaaatc
    20701 tttaaggcac tagctccaaa cataacggga atcccaagat agaaggtaaa ttctgtcaca
    20761 actgaacgac tggttccatt taacaaacca ccgacaatcg ttgcacctga acggctagtc
    20821 cctggtaaaa gagcaagaac ttggaagagt ccgatataga aagcggtcgt ataaggaagc
    20881 ttgtccaact ctgttacact tggctcgata gcacgcgctt tattgcgctt ttccaaatat
    20941 atgaaggcaa ccccgtagat aatcaacatg agagcaactg aaaccatgtt atggaagtgg
    21001 gtatcaaacc aatcatcaaa tttaaagaca ccaagtaaag gtaaagtagc aatcaagacc
    21061 ttcaaccata gtctccaagt cttacgaact tcctgtttgt ccttagtcgg tttaaaagga
    21121 ttgagcttgt taaaataaat caccataact gctaaaatag caccaagctg aatcacgaca
    21181 ttaaacatgg acataaaggc ttcattttga ttttggtatt ggataaactc ctctgctaaa
    21241 atcaagtgac ctgtactgga aatcggcaac cattccgtaa ttccttcaac aatcccgaag
    21301 aagatagatt ttaaaatttc aataagatac atatatttct ccttatatta tatttaacgc
    21361 agttagctac tgccaaagcc caagtggtat acttggaata agccactgtg gattagttca
    21421 tttcctccaa tcgcttgacg atttccgaaa gggtctaaca acagcttttt gtttcaattg
    21481 gtaatgagtt tgataacgca tagacgtttt atctcgtcta tggtaacaag gcaaaaagtt
    21541 cgtggataac caagtagact tgaaatacta tatctggagg tactcccatg ctttatgtgg
    21601 gcattgatgt cgctaaaaat aaacacgatg ttacagcctt gaatgttcga ggaaaactgt
    21661 tcttaaacca ctcacttttt caaataataa agctggtttt gaactcttag atctgtcttt
    21721 tcgacagctc aaccaagact gtctcatcgc tcttaaactt ctttctgacc ccaatcgtga
    21781 acaatttcaa cacgataatc ggcaaataga actaaaaata ctggctagac atattcatcg
    21841 tctcaagaaa aaacagtctg attggaaagt acaatacact cgttgtcttg atatcatctt
    21901 tcctgagttg gataaaatcg ttggaaagca ttcagaatat acctaccaac tcttgacacg
    21961 ctaccctaat cctcagaaaa ggcttgaggc aggatttgat aagctgatag aaattaagcg
    22021 attgaccgct tctaaaattc aggatatcct ctcagtcgca cctcgttcta tcggaacaac
    22081 atctcctgct cgtgaattcg aaatcatcga aatcatcaaa cattacaaga ggctcattga
    22141 caaggcggaa acatgtgtca atgacttgat ggctgagttc aactcggtca tcacgacggt
    22201 tactgggatt gggggtcgtt taggggcggt cattttagcc gagattcgaa atattcatgc
    22261 ctttgataat cctgctcaat tacaagcttt cgctggactg gattcttcta tttatcagtc
    22321 aggtcagatt gatttagctg gaagaatgat caaacggggt tcccctcatc tgcggtgggc
    22381 actcatacaa gctgccaaag catgcgctcg cttttcacct gcttttaagg cctatcttaa
    22441 gactaagtta gaataaggaa aacattacaa tgtagccatc atccaccttg caaaaaaact
    22501 tatccgaacc ctgttttata tcctaaaaaa gagctgccat ttgacgaaca aaaagtgatg
    22561 taatttctga aattaacaca ggattac
//
LOCUS       DAVLTG010000032        21880 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLTG010000032 DAVLTG010000000
VERSION     DAVLTG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.032"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            75..296
                     /locus_tag="VYN12_001333"
     CDS             75..296
                     /locus_tag="VYN12_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415714.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            813..1066
                     /locus_tag="VYN12_001334"
                     /pseudo
     CDS             813..1066
                     /locus_tag="VYN12_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1194..2423
                     /locus_tag="VYN12_001335"
     CDS             1194..2423
                     /locus_tag="VYN12_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1415715.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2443..5139
                     /gene="ppc"
                     /locus_tag="VYN12_001336"
     CDS             2443..5139
                     /gene="ppc"
                     /locus_tag="VYN12_001336"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1415716.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5222..5439
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5552..6556
                     /locus_tag="VYN12_001337"
     CDS             5552..6556
                     /locus_tag="VYN12_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1415717.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6625..7491
                     /locus_tag="VYN12_001338"
     CDS             6625..7491
                     /locus_tag="VYN12_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415718.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7488..8246
                     /locus_tag="VYN12_001339"
     CDS             7488..8246
                     /locus_tag="VYN12_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415719.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDAPKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8336..10096
                     /gene="dnaG"
                     /locus_tag="VYN12_001340"
     CDS             8336..10096
                     /gene="dnaG"
                     /locus_tag="VYN12_001340"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1415720.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10099..11208
                     /gene="rpoD"
                     /locus_tag="VYN12_001341"
     CDS             10099..11208
                     /gene="rpoD"
                     /locus_tag="VYN12_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1415721.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11222..11551
                     /locus_tag="VYN12_001342"
     CDS             11222..11551
                     /locus_tag="VYN12_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1415722.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11666..12709
                     /gene="cpoA"
                     /locus_tag="VYN12_001343"
     CDS             11666..12709
                     /gene="cpoA"
                     /locus_tag="VYN12_001343"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1415723.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12725..14050
                     /locus_tag="VYN12_001344"
     CDS             12725..14050
                     /locus_tag="VYN12_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1415724.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14081..14257
                     /locus_tag="VYN12_001345"
     CDS             14081..14257
                     /locus_tag="VYN12_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1415725.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14316..14450
                     /locus_tag="VYN12_001346"
     CDS             14316..14450
                     /locus_tag="VYN12_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1415726.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14514..15824
                     /gene="obgE"
                     /locus_tag="VYN12_001347"
     CDS             14514..15824
                     /gene="obgE"
                     /locus_tag="VYN12_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1415727.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15834..15992
                     /locus_tag="VYN12_001348"
     CDS             15834..15992
                     /locus_tag="VYN12_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415728.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17079..18338
                     /locus_tag="VYN12_001349"
     CDS             17079..18338
                     /locus_tag="VYN12_001349"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1415729.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18354..18905
                     /locus_tag="VYN12_001350"
     CDS             18354..18905
                     /locus_tag="VYN12_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415730.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18898..20175
                     /locus_tag="VYN12_001351"
     CDS             18898..20175
                     /locus_tag="VYN12_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1415731.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20191..21051
                     /locus_tag="VYN12_001352"
     CDS             20191..21051
                     /locus_tag="VYN12_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1415732.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21276..21386
                     /locus_tag="VYN12_001353"
                     /pseudo
     CDS             21276..21386
                     /locus_tag="VYN12_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            21432..21880
                     /locus_tag="VYN12_001354"
                     /pseudo
     CDS             21432..21880
                     /locus_tag="VYN12_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6709 a         3761 c         4905 g         6505 t
ORIGIN      
        1 tcaaaatgtc cagttaggac actttgaatg atttcttagt tttatatatt atacttttct
       61 caggagaaag ctagatgtac agacgtttga gagatttgag ggaagatcac gatttgaccc
      121 aaaaacaaat agctaaaata ctttcgttta caaactcagc ttatgctaaa attgaacggg
      181 gtgagcatac gttaacagca gatgtattgg taactctctc aaacttttac gatgtcagta
      241 cagactacct attggaattg acagattttc ctgataaaat tcgctttaga aaataatctc
      301 ctcaatttca tagagtgtga aaatgaggag attttttatt tgttctttga aaattaaata
      361 gtccaaaatg gtactttcct catttgtgga gcaaatttga atggctcgcc atgataagag
      421 cgattttaaa accatcaata aaatagagcg atactttata tgccatgata caaatgatat
      481 acaatgatac ttctgaccgt tcaggctgcc atcgtaaaag agcagcaagt gaaattctta
      541 tgatgacttc atcagtcatg ccacgttaaa tgtgtgagtt tgttagagaa acgcaattaa
      601 tcctcaaaag gttccccgaa ccttttgagt tccacagacg catcacgtgg agtgtgtaag
      661 cttgttgcta aaagcgtaaa aaccttggaa cgaaaggaat aatagacttc ctgcgaaaca
      721 aaaatacaat acaataaaac tatggatgat gaagcaagta aacaattaag cgatagccgt
      781 ttcaagagcc ttgtaggtgt tcagcgcacg agatgttagc tgtgttaaaa acagcttatc
      841 aacgcaacgt aaacgcgcaa aaggtggacg aaaaaccaaa ttaagcctag acgatctcct
      901 catggtaact attcaataca tgcgagaata gcgcacttat gaacaaattg cggctgattt
      961 tggcattcac gaaagcaact taatccgtcg gagccaatgg gttgaagtaa ctcttgttca
     1021 aaatggtttt acgatttcaa attctgccct aattatgaaa aacagtaaaa ttcgaaggat
     1081 tgtaaggtaa gagttttttt ctttctgaaa aaatggtata atagcaatca aaactagaaa
     1141 ataaaacgga atttggaaca gatttgtctg tatcctagta gagtggtgat gctatgaaga
     1201 ttagtaagag gcacttatta aattattcca tcttgattcc ctacttgctt ttatctattt
     1261 tgggcttgat tgtggtctat tcgaccacca gtgctatttt aattgaagaa ggcaagagcg
     1321 ccttgcagtt ggttcgaaac caaggaatct tttggattgt tagtttgata ctgattgcct
     1381 taatttataa attgagacta gattttttga gaaatgagcg actaatcatt ttagttatat
     1441 taatagaaat gcttttattg ttcttggctc gttttattgg tatttccgta aacggggcat
     1501 acggttggat ttcggttgca ggagtaacta ttcagccagc tgagtactta aaaatcatta
     1561 ttatttggta tttagctcac cgattctcca aacagcaaga agaaatagct acttatgatt
     1621 ttcaagtttt gactcaaaat caatggcttc cccgtgcttt taatgattgg cgattcgttc
     1681 tcctagttct gattggaagt ttgggaattt tccctgattt aggaaatgcg actattttag
     1741 tcttggtttc cttgattatg tatacagtta gtggaatcgc ttatcgctgg ttttcaacca
     1801 ttctggcgct cgtatctgcc gcttctgtct ttgtcttgac cactatcagc ctaatcggtg
     1861 ttgagacctt ttcaaaaatt ccagtatttg gctatgtagc caagcgcttt agtgcctttt
     1921 ttaatccttt tgccgatcgt gctgatgcag gtcaccagtt agctaattct tattttgcca
     1981 tggtcaatgg tggttggttt ggtctaggtc ttggaaactc gattgaaaaa cgaggttatt
     2041 tgccagaagc tcatacagac tttgtctttt ctatcgtgat tgaagaattt ggctttgctg
     2101 gtgccagtct tattttagct ctcttgtttt tcatgatttt gcggattatc ttggtcggta
     2161 ttcgagcgga gaatcctttc aatgccatgg ttgcactcgg tgtcggaggg atgatgttgg
     2221 ttcaggtatt tgtcaatatc ggagggattt cgggcttgat tccatctaca ggagtaacct
     2281 tccccttctt atcccagggt ggaaatagtc ttctagtctt atcagtggca gtagcctttg
     2341 tcttaaatat tgatgccagt gaaaaacgcg ctaagttgta ccgagaattg gaaaatcaac
     2401 caatgaacct tctgttgaag taggataaag aaaggatagt ttatgtctct tcaaaaatta
     2461 gaaaattata gtaataaaag tgttgtgcaa gaagaagtct tgattctaac agaattactg
     2521 gaagatatta ctaaaaatat gcttgcccca gagacctttg aaaaaataat acagttgaaa
     2581 gaattatcaa cgcaggaaga ttatcaaggt ctaaaccgtc tagtgactag cttatcaaat
     2641 gatgaaatgg tctatatttc acgctatttc tctatcttac ctcttttgat caatatttca
     2701 gaggatgtgg atttagctta tgaaatcaat catcaaaata atattgatca ggactattta
     2761 ggtaaattat ctacaacgat taaattggta gcagaaaagg aaaatgccgt tgagatccta
     2821 gaacacttga atgttgtccc tgttttgaca gcccatccaa cacaagtgca acgcaaaagt
     2881 atgttggatt taacaaatca tattcatagt cttttgcgta aataccgtga tgttaagttg
     2941 gggttgatca ataaagataa atggtacaat gatttgcgtc gttacatcga aattatcatg
     3001 cagacagaca tgattcgtga gaaaaaatta aaagtgacta acgaaatcac gaatgctatg
     3061 gaatattata acagctcctt tttgaaagct gtacctcatt tgacgacgga gtataagcgc
     3121 ttagcgcaag cgcatggtct gaatttaaaa caggctaaac caatcaccat gggtatgtgg
     3181 ataggtggtg accgtgatgg aaatccattt gttacagcag agaccttgaa gcagtctgca
     3241 ctcactcaat gtgaagtcat catgaactac tatgataaaa agatttacca actttatcgt
     3301 gaattttctc tttcaactag cattgtcaac gtcagcaagc aagtcagaga aatggctcgt
     3361 caatccaagg ataactcgat ttaccgcgaa aaagagcttt accgtcgtgc cttgtttgat
     3421 attcaatcaa aaattcaggc aactaaaacc tatctgattg aggatgaaga agttgggact
     3481 cgttatgaaa ccgccaatga tttctacaag gatttgattg ccattcgaga ttctctacta
     3541 gaaaataagg gtgagtcctt gatttcaggt gattttgtgg aattattgca ggcagtagag
     3601 atatttggtt tttacctagc atcaattgat atgcgacaag actctagcgt ctatgaagcc
     3661 tgtgtggcag aactcttgaa atcagcagga attcattctc gttatagcga gttgagcgaa
     3721 gaagaaaagt gtgaccttct cttgaaagaa ttagaagaag atccccgaat tctttctgcg
     3781 actcacgcag aaaaatcaga attattagca aaagaattag ctatttttaa gacggctcgt
     3841 gttttgaaag ataagttggg agatgatgtc atccgtcaga ccatcatttc acatgcaacc
     3901 agcctttctg atatgctaga attagctatt ctgttaaaag aagtaggact ggtggatacg
     3961 gaaagggcgc gtgttcagat tgttcccctt tttgaaacaa ttgaagactt ggatcattca
     4021 gaagaaacaa tgagaaaata tctttctctt agccttgcca aaaaatggat tgactcacga
     4081 aataactacc aagaaatcat gcttggctac tctgacagta ataaagatgg cggttacttg
     4141 tcatcatgtt ggaccctcta caaggctcaa caacaattga ctgctattgg agatgaattt
     4201 ggcgttaagg ttaccttctt ccatggtcgt ggtggtactg tcggtcgtgg tggtgggcca
     4261 acctatgaag ccattacatc tcaaccgctc aagtctatca aggatcgtat ccgcttgacg
     4321 gagcagggtg aagtaattgg gaataaatac ggtaacaaag acgccgctta ctataacctt
     4381 gaaatgctag tatcggcagc tattaaccgt atgattactc agaagaagag cgataccaat
     4441 accccaaatc gttatgaagc cattatggat caagtagtgg accgtagtta cgatatctac
     4501 cgtgatttgg tctttggtaa tgagcatttc tatgattatt tcttcgagtc aagtccaatc
     4561 aaggctattt caagttttaa tattggttct cgtccagccg ctcgtaagac tattactgaa
     4621 atcggtggtt tgcgtgccat cccttgggta ttctcatggt cacagagtcg tgttatgttc
     4681 cctggatggt acggggttgg ttcaagcttc aaggaattta tcaataaaaa tccagagaat
     4741 attgctatct tacgagatat gtaccaaaat tggcctttct tccaatcgct tctttcaaat
     4801 gttgatatgg ttttgtcaaa atcaaatatg aatattgctt ttgaatatgc taaactttgt
     4861 gaagacgagc aagttaaggc catctatgag actattttaa atgaatggca agttactaag
     4921 aacgttatct tggctattga aggacatgac gaactcttag ctgacaatcc atatctaaaa
     4981 gctagtctgg attaccgtat gccttacttt aatattctca actatattca gttagagttg
     5041 attaaacgcc aacgtcgtgg agaattgtcc agtgatcaag aacgattgat tcatatcacc
     5101 atcaacggaa ttgcgacagg attgcgtaat tcaggttgat aattttcaag agtgaatgct
     5161 aaaagtgaat atcaaaaaaa ttctaataga ctattgacaa gtagtttaaa aatgatataa
     5221 tttaaccatt cagaaaagta atcatacaaa ctttttagag agtctgtggt agctgaaaac
     5281 agataagtgg cgatgatgaa aattgggctg aatgctattt agaatttgaa attataaaaa
     5341 ttcggtaagc acaccttaca gtgcatctcg ttattgcgag actgagcgat agggaaattc
     5401 cctataattg aggtggtacc gcgcatcgac gtcctcacac aagttttttg tgtgaggatt
     5461 tttttgatgg aggttagtat ggaaagaaaa cgatggcgtc gcttgtttag ataagtgaaa
     5521 tatgttaaag gaaataaaaa ggagaaacag aatgaaaaat aaacgtttaa ttggaattat
     5581 tgctgcatta gcagtcttag tagcaggaag cttgatttat tcttcaatga ataaatcaga
     5641 agctcagaat aataaggatg agaagaaaat aactaagatt ggtgtgcttc aatttgtgag
     5701 ccatccatcc cttgatttga tttataaagg gatccaagat ggacttgcag aagaaggata
     5761 taaagatgat caagttaaaa ttgattttat gaactcagaa ggtgaccaaa gtaaggttgc
     5821 gacaatgagt aaacaattgg ttgcaaatgg gaatgacctt gtggttggta tcgcaacacc
     5881 agcagcccaa gggttggcta gtgcaacaaa agacctaccg gttatcatgg ccgctattac
     5941 agacccaatt ggtgctaact tggttaaaga tttgaaaaaa ccaggtggca acattacagg
     6001 ggtatctgac cacaatccag ctcaacaaca agttgaactc atcaaggctc tgacaccgaa
     6061 tgtgaaaaca atcggagctc tttactcaag tagcgaagac aattcaaaaa cacaggtcga
     6121 agaatttaag gcttatgctg aaaaagcagg tctgacagtg gaaacatttg cagttccttc
     6181 aacaaatgaa attgcctcaa ctgtcactgt tatgactagc aaggtagatg ctatttgggt
     6241 tccaattgat aacaccattg catcaggatt tccaacggtt gtctctagca atcaaagttc
     6301 taagaaacca atttatccca gtgcgacagc tatggtagaa gtaggtggtt tggcatcagt
     6361 tgtaattgac caacatgacc ttggtgtggc aacaggtaaa atgattgtgc aagtcttgaa
     6421 aggtgcaaaa ccagccgata ccccagtcaa tgtcttttca actggtaagt cagtcatcaa
     6481 taaaaaaata gcacaagaac taggtattac tattcctgag tctgttctca aagaagcagg
     6541 acaagtcatc gaataaataa ggtagggagg aggagactct tcccattttt taaaaagatg
     6601 aatatagaaa ggattaaata aaatatgatt gtttccatta tttctcaagg atttgtctgg
     6661 gctattctag gtctgggaat ctttatgaca tttaggattt taaactttcc agatatgacg
     6721 acagaaggtt ccttccctct tgggggagct gttgctgtca ctttgataac caaaggcgtg
     6781 aacccatttt tagcgacact tgttgctgta ggagcaggtt gtttggctgg aatggcagca
     6841 ggccttcttt atacaaaagg gaagatccca accttgctct cagggatttt ggtgatgact
     6901 tcttgtcact caatcatgct cttgattatg ggacgtgcga atttaggcct gcttggaacc
     6961 aagcaaattc aggatgtttt gccttttgat tcggatttga atcaactctt gacaggtctc
     7021 atctttgtga gtattgttat tgctctcatg ctctttttct tggacactaa actcggacaa
     7081 gcctatattg ctacagggga taatcctgat atggctagaa gtttcgggat tcatactgga
     7141 cgcatggagc tcatgggctt ggtcttatca aatggtgtga ttgcccttgc aggtgccctc
     7201 attgctcagc aagaaggtta tgccgatgtg tctcgaggga tcggggttat cgttgtgggg
     7261 cttgcaagtt tgattattgg agaagttatt ttcaagagtt tgagcttggc agagcgtttg
     7321 gttactatcg ttgtaggttc tatcgcttat caatttttag tgtgggcagt tatcgcactt
     7381 ggctttaata caagttacct tcgtttatac agtgccttga ttttagcagt ctgcctcatg
     7441 attccaacat ttaagcaaac aatcttgaaa ggagccaagt taagcaaatg acagcaattg
     7501 tagaattaaa aaatgcaacc aaaatcgtta aaaatggctt tgatgaagaa aagattattt
     7561 taaatgatgt ttccttagaa atttttgaac gggactttat cacgattttg ggcggaaatg
     7621 gtgctggaaa atcaaccctc tttaacacta tagcagggac cttatcacta actagtggaa
     7681 ctatccgtat tttaggtgaa gaactcacta agttttcacc cgagaagcgt gccaagtacc
     7741 tgtctcgtgt cttccaagat ccaaagatgg ggacagctcc ccgtatgacg gtcgctgaaa
     7801 atcttttaat cgccaagttt cgtggtgaaa agcgtggatt gttaccacga cgcttgacta
     7861 gctataagga tgaatttcag gcaaccattg aaaaagtagg aaatggtctt gagaaacact
     7921 tgaatacacc gattgagttc ttatcaggtg gacaaagaca ggctttgagt ctcttgatgg
     7981 caaccttgaa gcgacctgaa ttactcctgt tagatgagca tactgctgcc ctggatccaa
     8041 agactagtgt tgctttgatg gaattgacag atgaatttgt taagaaagat cagctaacag
     8101 cccttatgat tactcatcat atggaagatg ctcccaaata cggcaatcgc ttgattgtca
     8161 tgaaagaagg acggattatc caagatttaa accaagaaga aaaagcaaaa atgaaaatct
     8221 ctgattatta tcaactcttt gaataaagta gggaaaatga gtgaaatggt ttactttttt
     8281 tctgaaataa agtatactat ataaagtaaa ctatgataac atggaggtat tgtgtatggt
     8341 tgacaaacaa gtcattgaag aaatcaaaaa caatgccaac attgtggaag tcataggaga
     8401 tgtgatttct ttacaaaagg caggacggaa ctatctaggg ctctgtcctt ttcatggtga
     8461 aaaaacacct tctttcaacg ttgtagagga taagcagttt tatcactgtt tcggttgtgg
     8521 tcgctcaggt gatgtcttta agttcatcga ggagtaccaa ggggttccct ttatagaggc
     8581 agtccaaatc ttaggtcagc gtgttggaat tgaggttgaa aaaccgcttt atagtgagca
     8641 gaagccagcc tcacctcacc aagctcttta tgatatgcac gaagatgcag ccaaatttta
     8701 ccatgcgatt ctcatgacaa cgactatggg cgaagaggcc agaaattacc tttatcagcg
     8761 gggtttgaca gatgaagtgc ttaaacattt ttggattggt ttagcacctc cagaacgaaa
     8821 ctatctctat caacgtttgt ctgatcagta tcgtgaagag gatttactgg attcaggcct
     8881 gttttatctc tcggatgcca atcaatttgt agacaccttt cacaatcgca ttatgtttcc
     8941 cctgacaaat gaccaaggaa aggtcattgc cttctcaggt cgtatctggc aaaaaacgga
     9001 ttcacaaact tctaagtata aaaacagccg atcgactgca atttttaaca aaagttacga
     9061 attatatcat atggataggg caaaaaaatc ttctggaaaa gctagtgaga tttacttgat
     9121 ggaaggattc atggatgtta ttgcagccta tcgggctgga atcgaaagtg ctgtggcgtc
     9181 gatgggaacg gccttgagtc gagagcatgt tgagcatctg aaaaggttaa ccaagaaatt
     9241 ggttcttgtt tacgatggag ataaggctgg gcaagccgcg acattgaaag cattggatga
     9301 aattggtgat atgcctgtgc aaatcgtcag catgcctgat aacttggatc ctgatgagta
     9361 tctacaaaaa aatggtccag aagacttggc ctatctatta acgaaaactc gtattagtcc
     9421 gattgagttc tacattcatc agtacaaacc tgaaaacagt gaaaatctgc aggctcagat
     9481 tgagtttctt gaaaaaatag ctcccttgat tgttcaagaa aagtccatcg ctgctcaaaa
     9541 cagctatatt catattttag ctgacagtct ggcgtccttt gattataccc agattgagca
     9601 gattgttaat gagagtcgtc aggtgcaaag gcagaatcgc atggaaggaa tttccagacc
     9661 gacgccaatc accatgccaa tcaccaagca gttatcggct attatgaggg cagaagccca
     9721 tctactctat cggatgatgg aatcccctct tgttttgaac gattaccgtt tgcgagaaga
     9781 ctttgcattt gctacacctg aatttcaggt cttatatgac ttgcttggcc agtatggaaa
     9841 tcttcctcca gaagttttag cagagcagac agaggaagtt gaaagagctt ggtaccaagt
     9901 tttagctcag gatttgcctg ctgaaatatc gccgcaggaa cttagtgaag tagagatgac
     9961 tcgaaacaag gctctcttga atcaggacaa tatgagaatc aaaaagaagg tgcaggaagc
    10021 tagccatgta ggagatacag atacagccct agaagaattg gaacgtttaa tttcccaaaa
    10081 gagaagaatg gagtaataat ggcaacaaaa caaaaagaag taacaacatt tgacgtacag
    10141 gtagcagaat ttatccgtaa tcataagcaa aaagggacag caacagatga tgaaatcaat
    10201 gcaagtctgg ttattccttt taccttggac gctgatggga ttgaagatct cttgcaacgg
    10261 attcaggatg caggaatttc tatcacagat aacgaaggaa atccaagtgc gcgtgttctt
    10321 agcaatgaag aagaaccaga actcagcgat gaggacttga ttgggtcaac ttctgctaag
    10381 gtcaatgacc ctgtccgtat gtacttgaaa gaaatagggg tcgttcctct cttgaccaat
    10441 gaagaggaga aagagttggc actggctgtt gaagctggtg atatcgaagc caaacaacgt
    10501 cttgcggaag ccaatcttcg tttggttgtt tccattgcca aacgctatgt cggtcgtggc
    10561 atgcagttcc ttgacttgat tcaagaagga aatatgggct tgatgaaggc ggttgacaag
    10621 tttgactatt ctaaagggtt caagttttca acttatgcaa cttggtggat tcgtcaggct
    10681 atcactcgtg ctattgcgga ccaagctcgt accatccgta tcccagttca catggttgaa
    10741 actatcaata aattggttcg tgaacagcgg aatctccttc aagaattggg gcaagatccg
    10801 acaccagaac agattgctga acgaatggat atgacacctg ataaggttcg tgaaatcttg
    10861 aagattgccc aagaaccagt atctcttgaa actcctatcg gtgaagagga cgatagccac
    10921 cttggagact ttatcgaaga tgaagtgatt gaaaatccag tggattatac gactcgtatc
    10981 gtcttgcgtg agcaattgga tgaaatctta gatactctta cagaccgtga agaaaatgtt
    11041 ctgcgtctac gttttggact agatgatgga aaaatgcgca cacttgaaga tgtggggaaa
    11101 gtctttaacg taactcgtga gcgtatccgt cagattgaag caaaggcttt gagaaaacta
    11161 cgccaaccaa gtcgtagcaa accgcttcgt gattttattg aagactaaga gtgaggaaaa
    11221 tatggcttat acagaagagc aaattgaaaa catcaaaaca cggattttaa cagccttgga
    11281 agaagtcatc gaccctgagt tgggaatcga tattgtcaat cttggtttga tctatgagat
    11341 tcgttttgac ggtgacacag ggcaaacaga gattgacatg actttgacaa ctatgggttg
    11401 tcccttagca gaccttttga cagaccagat ttatgatgct atgatagagg ttccagaagt
    11461 aacggatact gaggttaaat tagtctggta tccagcctgg acagttgaaa aaatgagtcg
    11521 ctatgcccgc attgccctag gcattaagta aacatataaa agcatgtgag agactgttgg
    11581 aaaagcgagg aaatttcccc tcttttcctc tagtctctcc tttcttttgc tgattttatt
    11641 caaagaaaat gatataatag tagttatgga gaaaaagaaa ttacgcatca atatgttgag
    11701 ttcaagtgag aaagtagcag gacagggagt ttcaggtgct taccgtgaat tagttcgtct
    11761 tcttcaccgt gctgccaagg accaattgat tgttacagaa aatcttccaa tcgaggcaga
    11821 tgtgactcac tttcatacga ttgattttcc ctattattta tcaaccttcc aaaagaaacg
    11881 ctcagggaga aagattggct atgtgcattt cttgccagct acacttgagg gaagtttgaa
    11941 aattccattt ttcttaaagg gaattgtgaa acgctatgta ttttcttttt acaaccggat
    12001 ggagcacttg gttgtggtca atcctatgtt tattgaggat ttggtagcag ctggtattcc
    12061 acgtgaaaaa gtgacctata ttcctaactt tgtcaacaag gaaaaatggc atcctctacc
    12121 acaagaagag gtagtcagac tgcgcacaga tcttggtctt agtgacaatc agtttatcgt
    12181 agtaggtgct gggcaagttc agaaacgtaa agggattgat gactttatcc gtctggctga
    12241 ggaattgcct cagattacct ttatctgggc tggtggcttc tcttttggtg gtatgacaga
    12301 tggttatgaa cactataaga aaattatgga aaatccccct aaaaatttga tttttccagg
    12361 cattgtatcg ccagagcgga tgcgcgaatt gtatgctcta gcggatcttt tcttgttgcc
    12421 tagttacaat gagctctttc ctatgactat tttagaagct gcgagttgtg aggctcctat
    12481 tatgttgcgt gatttagatc tctataaggt aattttggag ggaaattatc gggcgacagc
    12541 gggtagagaa gagatgaaag aggctatttt ggaatatcaa gcaaatcctg ctgccttaaa
    12601 agatctcaaa gaaaaggcta agaatatttc cagagagtat tctgaagagc atctgttaca
    12661 aatctggttg gacttttatg agaaacaagc cgctttaggg agaaagtaaa aagtgaggta
    12721 atctatgcga attggtttat ttacagatac ctattttcct caggtttctg gtgttgcgac
    12781 cagtattcga accttgaaaa cagaacttga aaagcaggga catgctgttt ttatctttac
    12841 gacgacagat aaggatgtca atcgctacga agattggcaa attatccgca ttccaagtgt
    12901 tcctttcttt gcttttaagg atcgtcgctt tgcctaccga ggttttagca aggcacttga
    12961 aattgctaaa cagtatcagc tagatattat ccatactcag acagaatttt ctcttggcct
    13021 gttggggatt tggattgcgc gtgaattgaa aattccagtc atccatacct atcacaccca
    13081 gtatgaagac tatgtccatt atattgctaa ggggatgttg atccggccga gtatggtcaa
    13141 gtatctggtt agaggtttcc tgcatgatgt ggatggggtt atttgtccta gtgagattgt
    13201 ccgtgacttg ctatctgatt ataaggtcaa ggttgaaaaa cgggtcattc ctactgggat
    13261 tgaattagcc aagtttgagc gtccggaaat caagcaggaa aatttgaaag aactgcgtag
    13321 taaactaggg attcaagatg gtgaaaagac gttgcttagt ctttcgagaa tctcctatga
    13381 aaaaaatatt caagcagttt tagcagcctt tgctgatgtt ctgaaagagg aagacaaggt
    13441 taaactggta gtagctgggg atggccctta tctgaatgac ctcaaagagc aagctcagaa
    13501 cctagagatt caagactcag tcatctttac agggatgatt gctcctagtg agacggctct
    13561 ttactataaa gcggcggatt tcttcatttc ggcatcgaca agcgaaacgc aaggtttgac
    13621 ctacttggaa agcttagcca gtggaacacc tgtcattgct cacggaaatc cttatttgaa
    13681 caacctcatc agtgataaaa tgtttggaac cttgtactat ggagaacatg atttggctgg
    13741 tgctattttg gaagccctga ttgcaacacc agacatgaac gagcatacct tatcagagaa
    13801 attgtatgag atttcagctg agaactttgg gaaacgagtg catgagtttt atctggatgc
    13861 cattatttca aataacttcc agaaagattt ggctaaagat gatacggtca gtcagcgtat
    13921 ctttaagaca gttttgtatc ttcagcaaca ggtggttgct gtacctgtaa aaggatctag
    13981 acgcatgttg aaggcttcaa aaacacagtt gatcagtatg agagactatt ggaaagacca
    14041 tgaagaatag aaagaggaac agctatgaaa aaaacaatta atgagaagcg gtcgtgataa
    14101 aaagattgcg ggtgtttgtg ctggggtggc ccattatctg gatatggatc cgactatcgt
    14161 tcaagtcatt tggggtgttc ttacttgctg ttacggagct ggaattgtag cttacattat
    14221 tttatggatt atcgcaccag tagcaactga ctattgaaaa ctagctcaat tcatgctaag
    14281 ataatagaaa atagaatgta acgaaggaga gaaaaatggc atttggagat aatggaaatc
    14341 gtaaaaaaac tatgtttgag aaaataacct tgtttatcgt gattatcatg ctagtagcaa
    14401 gtttattggg aatttttgca actgcaattg gtgccctcag taatctataa aatagattca
    14461 agaaaattta gtgactggga tttcccagcc cttttttaaa gtgagaagaa ataatgagta
    14521 tgtttttaga tacagctaag attaaggtca aggctggtaa tggtggcgat ggtatggttg
    14581 cctttcgtcg tgaaaaatat gtccctaatg gaggcccttg gggtggtgat ggtggtcgtg
    14641 gaggcaatgt ggtcttcgtt gtagacgaag gactacgtac cttgatggat ttccgctaca
    14701 atcgtcattt caaggctgat tctggtgaaa aagggatgac caaagggatg catggtcgtg
    14761 gtgctgagga ccttagagtt cgagtaccac aaggtacgac tgttcgtgat gcggagactg
    14821 gcaaggtttt aacagatttg attgaacatg ggcaagaatt tatcgttgcc cacggtggtc
    14881 gtggtggacg tggaaatatt cgtttcgcga caccaaaaaa tcctgcaccg gaaatctctg
    14941 aaaatggaga accaggtcag gaacgtgagt tacaattgga actaaaaatc ttggcagatg
    15001 tcggtttagt aggattccca tctgtaggga agtcaacact tttaagtgtt attacctcag
    15061 ctaagcctaa aattggtgcc taccacttta ccactattgt accaaattta ggtatggttc
    15121 gcacccaatc aggtgaatcc tttgcagtag ccgacttgcc aggtttgatt gaaggggcta
    15181 gtcaaggtgt tggtttggga actcagttcc tccgtcacat cgagcgtaca cgtgttatcc
    15241 ttcacatcat tgatatgtca gctagcgaag gccgtgatcc atatgaggat tacctagcta
    15301 tcaataaaga gctggagtct tacaatcttc gcctcatgga gcgtccacag attattgtag
    15361 ctaataagat ggacatgcct gagagtcagg aaaatcttga agaatttaag aaaaaattgt
    15421 ctgaaaatta tgatgaattt gaagagttac cagctatctt cccaatttct ggattgacca
    15481 agcaaggtct ggcaacactt ttagatgcta cagctgaatt gttagacaag acaccagaat
    15541 ttttgctcta cgacgagtcc gatatggaag aagaagctta ctatggattt gacgaagaag
    15601 aaaaagcctt tgaaattagt cgtgatgacg atgcgacatg ggtactttct ggtgaaaaac
    15661 tcatgaaact ctttaatatg accaactttg atcgtgatga atctgtcatg aaatttgccc
    15721 gtcagcttcg tggtatgggg gttgatgaag cccttcgtgc gcgtggagct aaagatgggg
    15781 atttggtccg cattggtaaa tttgagtttg aatttgtaga ctaggagact ggtatgggag
    15841 ataaaccgat atctttccga gatgcggatg gtaattttgt ttccgccgca gacgtttgga
    15901 atgaaaagaa attggaagaa ctatttaatc gtctcaatcc aaatcgtgcc ttgagattgg
    15961 cacgaactaa aaaggaaaat ccatctcagt aaagaagcta aaaaatcccg tgcctcatca
    16021 gacacgggat tttgtggtac gacaggcatg tatagcaaac tgaatctgga atagcacagc
    16081 atatcttcta aaatattgct ataaattgat ttgaatttca aaattaaatt gttttattct
    16141 tatttcaatt tgttatagta tatctgatgt caaagttctc ggcgagtcaa atagtgattc
    16201 ccaagcctga ctatcgtgag gtagcggatt aaaatggtct ggggatagac cgttttaagt
    16261 ctgatgctgg aaataagaat tgtcagaaga agggatagcg aaatcgtggc tctacgaaca
    16321 ggaacgtgat aataaggcgt atatagcgaa taagagggcc tcaaactcta aagtccaaaa
    16381 aggtagtcgt aacctatatg cgtaaatcat gagagtaatt gaattcgtac taagattttc
    16441 tatttttact gtaacctttt aacgtcctca tatcttgtat acacgaggaa agatgtacga
    16501 cttatcccgt gaggtctatc actataaaga gaaaacgaca gatagaagtg atcctgagtc
    16561 acggttatct ttaaaataga ttgtctgata ggatgctagc ctgaaaacgt cttgttcatg
    16621 aaatatagga cggtatgtat aaaacgcttc tgtgaactga gagaaggggg agaagttctt
    16681 gctaaaattt agttgaacag ccgtattccg atacttagat aagagatcta gtcttagctc
    16741 ctactcagtt tcaggggata aaaaaggggc aatagcgatt cgagaaagat tatactcttc
    16801 gaaaatctct tcaaatcacg tcaatatcgc cttgccgtat gtgtaggata ctaactacgt
    16861 cagttccatc tacaatctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt
    16921 gatctttgat ttttattgag tattagtaat tcagttacta actcgtcaac tctgatttat
    16981 ccaataaaat tgaaaaggat ggaaaaaagg ataaatttat gatatacttt attttgaaga
    17041 ccttattaga aatcttgaaa gagtattgaa aacttagaat gagaaaaatt gttatcaatg
    17101 gtggattacc actgcaaggt gaaattacta ttagtggtgc taaaaatagt gttgtggcct
    17161 taattccagc tattatattg gctgatgatg tggtgacttt ggattgtgtt ccagatattt
    17221 cggatgtagc cagtcttgtc gaaatcatgg aattaatggg agctactgtt aagcgttatg
    17281 acgatgtctt ggagattgat ccaagaggtg ttcaaaatat tccaatgcct tatggtaaaa
    17341 ttaacagtct tcgtgcatct tactattttt atgggagcct cttaggccgt tttggtgaag
    17401 cgacagttgg tctaccggga ggatgtgatc ttggtcctcg tccgattgac ttacacctta
    17461 aggcgtttga agctatgggt gccactgcta gctacgaggg agataacatg aagttatctg
    17521 ctaaagatac aggacttcat ggtgcaagta tttacatgga tacggttagt gtgggagcaa
    17581 cgattaatac gatgattgct gcggttaaag caaatggtcg tactattatt gaaaatgcag
    17641 cccgtgaacc tgagattatt gatgtagcta ctctcttgaa taatatgggt gcccatatcc
    17701 gtggggcagg aactaatatc atcattattg atggtgttga aagattacat gggacacgtc
    17761 atcaggtgat tccagaccgc attgaagctg gaacatatat atctttagct gctgcagttg
    17821 gtaaaggaat tcgtataaat aatgttcttt acgaacacct ggaagggttt attgctaagt
    17881 tggaagaaat gggagtgaga atgactgtat ctgaagacag catttttgtc gaggaacagt
    17941 ctaatttgaa agcaatcaat attaagacag ctccttaccc aggctttgca actgatttgc
    18001 aacaaccgct tacccctctt ttactaagag cgaatggtcg tggtacaatt gtcgatacga
    18061 tttacgaaaa acgtgtaaat catgtttttg aactagcaaa gatggatgcg gatatttcga
    18121 caacaaatgg tcatattttg tacacgggtg gacgtgattt acgtggggcc agtgttaaag
    18181 cgaccgactt aagagctggg gctgcactag tcattgctgg gcttatggct gaaggtaaaa
    18241 ctgaaattac caatatcgag tttatcttac gtggttattc tgatattatc gaaaaattac
    18301 gtaatttagg agcggatatt agacttgttg aggattaaac cgtagaggtg tttatgaata
    18361 tttggaccaa attagcaatg ttttcttttt ttgaaacgga tcgcttgtat ttgcgtcctt
    18421 tcttttttag tgatagtcag gacttccgcg agatagcttc aaatccagaa aatcttcaat
    18481 ttattttccc aacgcaggca agtctggaag aaagtcaata tgcactggcc aattacttta
    18541 tgaagtcccc tttgggagtg tgggcaattt gtgaccagaa aaatcaacaa atgattggtt
    18601 ctattaaatt tgagaagtta gatgaaatca aaaaagaagc tgagcttggc tattttttga
    18661 gaaaagatgc ttggtcgcaa ggatttatga cagaggttgt tagaaaaatt tgtcagcttt
    18721 cttttgagga atttggctta aaacaattat ttatcattac ccaccttgaa aatgaagcta
    18781 gccaaagagt tgctcttaag tctggattta gtttgttccg tcagtttaag ggaagtgatc
    18841 gttacacaag aaaaatgcgg gattatcttg aatttcggta tgtaaaagga gagttcaatg
    18901 agtaagcatc aggaaattct aagctatttg gaggaattac cagtaggtaa aagggtcagt
    18961 gttcgtagca tttcgaatca tctaggagtt agtgatggaa cagcctatcg agctattaaa
    19021 gaagctgaaa accgtggaat tgtggagacc cgtcctagaa gtggaacaat tcgtgttaaa
    19081 tcccagaaag ttgctataga gagattaacg tttgctgaaa ttgcagaagt gacttcttct
    19141 gaggttctgg ctgggcaaga aggtttagag agagagttta gtaagttttc aattggtgcc
    19201 atgactgaac aaaatatctt gtcttacctt catgatgggg ggctcttgat tgtcggagac
    19261 cgaacccgta ttcagttgct agccttggaa aatgaaaatg cagttctggt tacaggggga
    19321 tttcaggttc atgatgatgt gcttaaactg gccaatcaaa aagggattcc tgttctaaga
    19381 agtaagcatg atacctttac cgtcgcgacc atgatcaata aagccttgtc aaatgtccaa
    19441 atcaagactg atattctgac agttgagaaa ctttatcgcc ctagtcatga gtatggtttt
    19501 ctgagagaga cagatacagt taaagattat ttggacttgg ttcgtaagaa tcgtagcagc
    19561 cgtttccctg ttatcaatca acatcaggtc gttgttggtg ttgtaaccat gagagacgct
    19621 ggtgataaat caccaagcac gacaattgat aaggttatgt ctcgtagtct attttgggtt
    19681 ggattatcga caaatattgc caatgtgagt caacggatga tcgcagaaga ctttgaaatg
    19741 gtaccagttg ttcgaagcaa tcaaactttg cttggcgttg tgacgcgacg agatgtcatg
    19801 gagaagatga gccgttccca agtttcggct ctaccaactt tttctgagca gattggacaa
    19861 aagctctctt atcaccatga tgaagtagtc attacagtgg aaccctttat gctagaaaaa
    19921 aatggagttt tggctaatgg tgtattggca gaaattctga cccacatgac ccaagattta
    19981 gttgttaata gtggtcgcaa tctcattatc gagcagatgc tgatctactt tttgcaggct
    20041 gttcagatag atgatatatt gcgcattcag gcacggatta ttcatcatac gagacggtca
    20101 gctataattg attacgatat ttatcatggt caccagattg tttcaaaagc aaatgtgact
    20161 gttaaaatta attagaaact aggagaaaag atgataacat taaaatcagc tcgtgaaatc
    20221 gaagctatgg acaaggctgg tgattttcta gcaagtattc atataggctt acgtgatttg
    20281 attaagccag gcgtagatat gtgggaagtt gaagaatatg tccgccgtcg ttgtaaagaa
    20341 gaaaatttcc ttccacttca gattggggtt gacggtgcca tgatggacta tccttatgct
    20401 acctgttgct ctcttaacga tgaagtggct cacgctttcc ctcgtcatta tatcttgaaa
    20461 gatggtgatt tgctcaaagt tgatatggtt ttgggaggtc ccattgctaa atctgaccta
    20521 aatgtctcaa aattaaactt caacaatgtt gaacaaatga aaaaatacac tcagagttat
    20581 tctggtggtt tagcagactc atgttgggct tatgctgttg gtacaccgtc cgaagaagtc
    20641 aaaaacttga tggatgtaac caaagaagct atgtacaagg gtattgagca agctgttgtt
    20701 ggaaatcgta tcggtgatat cggtgcggct attcaagaat acgctgaaag tcgtggttac
    20761 ggtgtagtgc gtgatttggt tggtcatggt gttggcccaa ctatgcacga agaaccaatg
    20821 gttcctaact atggtattgc aggtcgtgga ctccgtcttc gtgaaggaat ggtcttaacc
    20881 attgaaccaa tgatcaatac aggcgattgg gaaattgata cagatatgaa aactggttgg
    20941 gcgcataaga ccattgacgg tggattgtca tgtcagtatg aacaccaatt tgtcattacg
    21001 aaagatggac ctgttatctt gactagccaa ggtgaagaag gaacttatta ataaaaagtg
    21061 aaaagactac tggaagttta ttttgataaa aaatccagta gatcttttca taataaaacg
    21121 cattgtatca agtgttaggg gctgatatca tgcgtttttc tgcttttaag attttttcca
    21181 actctgtttg taagcgcatc ataacaaagg gtctaggatt cagggctctc ctcctatata
    21241 ctattagtaa agtaaaacta agggaggata ttttagtgtc gcagtctatt gttcctgtag
    21301 agattccaca atattgtcgt tttgattcta aaaagagaaa tggaattctg tttaacgttc
    21361 gtattgccaa tcttaaattt acctttttta gattagactt cctgcgaaat aaaatatggt
    21421 atagtagttc tatgaatgat gaagtaagta aacaactaac tgatgcagga tttaagcgtc
    21481 ttgtttgtgt tcagcgtacc acttttgaag agatgttagc tgtattaaaa acagcttatc
    21541 aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac cttcttatgg
    21601 ccactcttca atatgtgcga gaatatcgaa cttatgaaga aattgcgact gattttggta
    21661 tccacgaaag caacttaatc cgtcggagcc aatgggttga agtaactctt gttcaaagtg
    21721 gtgttacgat ttcaagaact cctctcagct ctgaggacac ggtaatgatt gatgcgacgg
    21781 aagtaaaaat caatcgccct aaaaaaacaa ttagcgaatg attctggtaa aaagaaatgc
    21841 tacgctatga aggctcaagc gattgtcaca agtcaaggga
//
LOCUS       DAVLTG010000033        21807 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLTG010000033 DAVLTG010000000
VERSION     DAVLTG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.033"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(26..223)
                     /gene="blpI"
                     /locus_tag="VYN12_001355"
     CDS             complement(26..223)
                     /gene="blpI"
                     /locus_tag="VYN12_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1415733.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            512..1099
                     /locus_tag="VYN12_001356"
     CDS             512..1099
                     /locus_tag="VYN12_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1415734.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1026..2669
                     /locus_tag="VYN12_001357"
     CDS             1026..2669
                     /locus_tag="VYN12_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1415735.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2680..4041
                     /locus_tag="VYN12_001358"
     CDS             2680..4041
                     /locus_tag="VYN12_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1415736.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4098..4226
                     /gene="blpC"
                     /locus_tag="VYN12_001359"
     CDS             4098..4226
                     /gene="blpC"
                     /locus_tag="VYN12_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1415737.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4297..5637)
                     /locus_tag="VYN12_001360"
     CDS             complement(4297..5637)
                     /locus_tag="VYN12_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1415738.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5651..6388)
                     /locus_tag="VYN12_001361"
     CDS             complement(5651..6388)
                     /locus_tag="VYN12_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415739.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6393..6731)
                     /locus_tag="VYN12_001362"
     CDS             complement(6393..6731)
                     /locus_tag="VYN12_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415740.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7007..7336
                     /locus_tag="VYN12_001363"
     CDS             7007..7336
                     /locus_tag="VYN12_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1415741.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7504..8553)
                     /locus_tag="VYN12_001364"
     CDS             complement(7504..8553)
                     /locus_tag="VYN12_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415742.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8550..9281)
                     /locus_tag="VYN12_001365"
     CDS             complement(8550..9281)
                     /locus_tag="VYN12_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415743.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9349..9759
                     /locus_tag="VYN12_001366"
     CDS             9349..9759
                     /locus_tag="VYN12_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1415744.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9769..10056
                     /locus_tag="VYN12_001367"
     CDS             9769..10056
                     /locus_tag="VYN12_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415745.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10218..10412
                     /locus_tag="VYN12_001368"
     CDS             10218..10412
                     /locus_tag="VYN12_001368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415746.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSNHTHD
                     KPTLTWFEEIFEEYHSPFHN"
     gene            complement(10746..11882)
                     /gene="dnaJ"
                     /locus_tag="VYN12_001369"
     CDS             complement(10746..11882)
                     /gene="dnaJ"
                     /locus_tag="VYN12_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1415747.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12641..14464)
                     /gene="dnaK"
                     /locus_tag="VYN12_001370"
     CDS             complement(12641..14464)
                     /gene="dnaK"
                     /locus_tag="VYN12_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1415748.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14944..15468)
                     /gene="grpE"
                     /locus_tag="VYN12_001371"
     CDS             complement(14944..15468)
                     /gene="grpE"
                     /locus_tag="VYN12_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1415749.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15495..16529)
                     /gene="hrcA"
                     /locus_tag="VYN12_001372"
     CDS             complement(15495..16529)
                     /gene="hrcA"
                     /locus_tag="VYN12_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1415750.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16693..17202)
                     /locus_tag="VYN12_001373"
     CDS             complement(16693..17202)
                     /locus_tag="VYN12_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1415751.1"
                     /translation="MNSRVEFRIFTILDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQEFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREELSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17809..20142
                     /locus_tag="VYN12_001374"
     CDS             17809..20142
                     /locus_tag="VYN12_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1415752.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20155..21618
                     /locus_tag="VYN12_001375"
     CDS             20155..21618
                     /locus_tag="VYN12_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1415753.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCDFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21618..>21807
                     /locus_tag="VYN12_001376"
     CDS             21618..>21807
                     /locus_tag="VYN12_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV1415754.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         6918 a         4442 c         4015 g         6432 t
ORIGIN      
        1 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
       61 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
      121 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
      181 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
      241 tcttttttct ttttttattt ttgtcttgtt gtaactttga taagtttagt atatcatcgt
      301 tttttaaaat ttttcatcca gatcttgaat tgtcatcgaa acgtcttgaa ttaggttttt
      361 tatttcaagc cacctctaaa tgtttaaaaa aaataatttc taatcacttt tttaccattc
      421 aggaagtttt aatgactatt caagatttca taaaatatga acttagtttt atgacataat
      481 agacctatcc actatatgaa aggaattgcc aatgacttct tataaacgta catttgttcc
      541 tcaaatagat gcgagagact gtggtgtcgc tgccttagcc tcgattgcta aattctatgg
      601 ttcagatttt tctctagctc acttgagaga acttgcaaag accaataaag aagggacgac
      661 tgctcttggc attgtaaaag ccgctgatga aatgggcttt gaaacaagac ctgttcaagc
      721 agataaaacg ctctttgaca tgagtgatgt cccctatcca tttatcgttc acgttaacaa
      781 agaaggaaaa ctccaacatt actatgttgt ctatcaaaca aagaaagact atctgattat
      841 tggtgatcct gacccttctg taaaaatcac taaaatgtca aaagaacgct ttttctatga
      901 atggactgga gtagctattt ttctagctac caaacccagc tatcaacccc ataaagataa
      961 aaagaatggt ctactaagca agcttccttc ctctgatttt caaacaaaaa tctctcattg
     1021 cttacattgt tctctcaagc ttattggtca ctattatcaa tataggtggt tcttactatc
     1081 tccaaggaat cttggatgaa tacattccaa atcagatgaa atcaacttta ggaatcatct
     1141 cagttggtct ggttatcacc tatatcctcc aacaagtcat gagcttctcc agagattatc
     1201 tcctaaccgt tctgagtcag agattaagta ttgatgtgat tttatcctat attcgccata
     1261 tttttgaact tcccatgtct ttctttgcga cacgtcgtac aggagaaatc atttcacgat
     1321 tcacagatgc taactctatt atagatgcct tggcttctac cattctttct ctttttctgg
     1381 atgtttctat tctgattctt gtaggaggcg tcttactggt acaaaaccct aatctcttcc
     1441 ttctttctct tatttccatt cctatataca tgttcatcat cttttctttt atgaaacctt
     1501 tcgaaaaaat gaaccatgat gtcatgcaaa gtaattctat ggttagctct gccattatcg
     1561 aagatatcaa cgggattgaa actataaagt cgctcacgag tgaagaaaat cgctatcaaa
     1621 atatagacag cgaatttgta gattatttgg aaaaatcctt taagctcagt aaatattcta
     1681 ttttacaaac gagtttaaag cagggaacaa aattagttct gaatatcctt atcctatggt
     1741 ttggcgctca attagtcatg tcgagtaaaa tttctatcgg tcagctgatt acctttaaca
     1801 cacttttttc ttactttaca actcctatgg aaaatattat caacctccaa accaaactcc
     1861 aatctgcgaa ggtcgctaat aaccgtttga acgaagtcta tctagtcgaa tctgaatttc
     1921 aagttcaaga aaaccctgtc cattcacatt ttttgatggg cgatattgaa tttgatgacc
     1981 tttcttataa gtatggtttt ggacgagata ccttaacaga tattaatctc acgattaaac
     2041 aaggagataa ggttagccta gttggagtta gtggttctgg taaaacaact ttagccaaaa
     2101 tgattgtcaa tttctttgaa ccctacaaag gacatatttc tatcaatcat caggatatta
     2161 aaaacattga taaaaaagtc ttgcgccgtc atattaatta cctaccacaa caagcctata
     2221 tctttaatgg ctctatcttg gaaaacttaa ctttgggcgg taatcatatg attagccaag
     2281 aagatattct aagagcttgt gaattagctg aaattcgtca agacattgaa agaatgccta
     2341 tgggctatca aactcagctc tctgatggag ctggtctatc aggaggacaa aagcaacgaa
     2401 tagccctcgc tcgtgctctt ttaactaaag ctcctgtttt aatactagac gaagctacta
     2461 gcggtcttga tgtcttgact gagaaaaagg ttatagataa tcttatgtct ctaactgata
     2521 aaaccattct ctttgtagcc catcgtctca gtatagccga acgaaccaac cgtgtcattg
     2581 ttcttgacca ggggaaaatc attgaagttg gtagtcacca agagttaatg caggcgcaag
     2641 gtttctacca tcatctattc aataaataag gagaatgtca tgaatcctaa tctttttaga
     2701 agcgtcgagt tttatcagag acgttaccat aactatgcga cagtgttcat tatacctctt
     2761 tcattactat ttactttcat cttgattttc tcccttgttg ccacaaaaga aattactgtt
     2821 acttcccaag gagaaatcgc ccctacaagt gtcattgcct ccattcagtc aaccagtgat
     2881 aatcctatcc tagctaatca tttagtggca aatcaagtag ttgaaaaagg ggacttactc
     2941 atcaaatact ctgaaacaat ggaagaaagt cagaaaactg ccttagcaac tcaattacaa
     3001 agacttgaga agcaaaaaga aggacttgga attttgaaac aaagcttaga aaaagcgact
     3061 gatctttttt ctggcgagga tgaatttggc taccataata cctttatgaa ttttactaaa
     3121 caatcccatg atattgaact gggtatcaca aagactaaca ccgaagtttc aaatcaagct
     3181 aatctttcca atagcagttc atcagctatt gaacaagaaa ttacaaaagt tcaacaacaa
     3241 attggagaat atcaagagtt gagagatgct atcataaata acagagcacg cttaccaact
     3301 ggcaatccgc accagtcaat tttgaatcgt tatcttgtag cctcacaagg acaaacacaa
     3361 ggaactgcag aggagccatt tttatctcaa attaatcaaa gtattgcagg tcttgaatca
     3421 tctatcgcaa gcctcaaaat tcagcaagct ggtatcggaa gtgtagcaac ttatgataac
     3481 agtttagcaa ccaaaattga agtactccgc actcagtttt tacagacagc ctcacagcaa
     3541 caactaactg tggagaatca attaacagaa ttaaaagtac aactagatca agccacacag
     3601 cgtttggaaa acaatacctt aacctcccca agtaaaggta tcgttcatct gaacagcgaa
     3661 tttgaaggta aaaatagaat tccaactggt acagaaattg ctcaaatatt ccctgtcatc
     3721 acagatacaa gagaagtact aatcacttac tacgtatctt ctgactatct acctctacta
     3781 gataaaggac aaactgtaag attaaaactg gagaagattg gaaatcacgg caccaccatc
     3841 atcggccaac ttcagacaat tgatcaaact cctaccagaa cagagcaagg aaatctcttt
     3901 aaattaaccg ctcttgcaaa actatctaac gaggatagta aactcatcca atatggctta
     3961 caaggtcgcg tcactagtgt aactacaaag aaaacatatt ttgattattt caaagataaa
     4021 attttaaccc attctgatta attttcagat aacactctat aactatttat tatcttatca
     4081 aaaaggagaa tcataacatg gataagaaac aaaacctaac ttcatttcaa gaactaacaa
     4141 ctaccgaact caaccaaatt acaggtggag gattgtggga agatttatta tataacatta
     4201 atagatatgc tcattacatc acataagaac ttcatcatcc aatacaacta taaaaaaata
     4261 agaccgagaa acaagtactc tcggtcttat ttttcatcat tctgtatgta tcacagtaag
     4321 tacctgacga aagacttgat tttgacaggt ggtatttaga ctggtattag gatggctttc
     4381 cacaatcttc atgacggtat agagaccaac tcctctctcc tcccctttag aactggctcc
     4441 aaaggagaag atttcagaaa tatcgatgcc ctcttctttg atggagtttt cgatgataaa
     4501 ggtctcctgt gctccatttt ttaaaaaggc gattgaaaca tgaggttgac tagcttccac
     4561 actggcttca atagcattgt cacaaaggat agacacaatg gttagaaaat caagtagact
     4621 catcccctcg acctgaatct cctcaggaac ttcgacatta aagacaatgt tcttatctct
     4681 ggcttttaaa aatttccctg ctagaagact tttgagggct ttatcacgaa tatttaccaa
     4741 tctgcccagg tcatatttat tgttctgcaa tttctgactg gaatccttta agacggagcc
     4801 atagacctct tttatctgct ccatatcctc ctcttcaatg cccagacgta agctagtcaa
     4861 gaggttggta taatcatgac gaaagctccg tacttccttg taaagctcct ctatatgccg
     4921 actatagcgt tccatatctc tatagcgcag ggcctgctct tgttccaatc tctcatagag
     4981 tttttccttc aaataggtat ccaatttctt gataaccccc ataaaaaaga gtaggtaaaa
     5041 gactaggatg agatggcgaa cagtctttga ttgaatactt tgttcatatt caaaaaaaga
     5101 cagactttcc atgactagat agtagccacc cattatccag ttaatctgag tcagggactt
     5161 ttgaaaggct ttatcgagaa tctcctttct caagctagta aaatcgtagt ccaaccattt
     5221 caaaaaagct agagaaatga agaaattgaa aattattata cataacccag taaatgagta
     5281 gccatcatat acttgccctt gtcccaaaaa tggaagcaca aaataggaga ctcctctata
     5341 aaagagattc accaatatca ttggaaagag accataaaag aaaaggagtt ttttaggaag
     5401 ccctctcaat aataagaaag ataagcctat gccgtacaag ggttccataa aataagatag
     5461 gtaaacattt cctactatat agctaatcat cacaaaaaca aaggccaaca gtatcttaaa
     5521 aagaaaggcc ttaaaaatcc tctcgaaagt aagatcaatt ccatccacct taaagaagat
     5581 gacaatttct agtccattag taacaagtgt atacaacaat atccaagcaa tgttcataaa
     5641 ttctcctagc tcagtgtaat ttattgatgg cctcagacac ttccctgacc ttataacggg
     5701 cgattagaca acttccacca ttgggaaaga aaagcagttt ttctttctta tccaaatgca
     5761 ccacatttgc aggattgatg agaaaagagc ggtggcactg caagagacgg ggctcctgct
     5821 tgaaaacctc ctctaaactc gctgtaaatt ccagcctgtc tgtcttggta tagagaataa
     5881 cacgatgggc tctgggcgac gtttcgagat agtaaacctc tttaaaagga tactgaaatt
     5941 gggcaaattt tgatttaaag taaaagcaat cttccgccag acttttacta tcttgactat
     6001 tggcatagag gagggctgtc tcgatccgag attcaaactc ctctgctgac aaggccttat
     6061 caatgtagtc caaagcagac acttggtagc gaaaagacag gggcataaac tccgagtgag
     6121 tcgtcacaaa gacaatcagg gcataaggat cccgatcccg aatctttcta gccacttcca
     6181 gtcccttcat ctcttcattt cgaatctcaa tatccaaaaa gaatagctga tgggccccct
     6241 tctcatgcac ttcagccagc agttggtccg gcttgccaaa tacctcaaaa gagctaggaa
     6301 tgatatgatg tgctttcaaa agtttctcaa tcgtcgtttc aattctagtc tgttgggaaa
     6361 aatcatcctc taaaacaaat attctcatct tcttactctc cctctttcaa ccatttttga
     6421 cgaatttctc tatagcgacg tctggcatac ttgacagcgt attgaccttc ttctccgaga
     6481 aaaaggattc tttcttgaaa atcaatcgat tttaatttat caagattaac caaacaattt
     6541 cgatgacatc tcatcaaggt ttccccacat tggttctcaa gattacttaa attttgaagc
     6601 atattaaaac tagcttcttc tgtaacaatc tgtacggtat gggctttagt tggatgtgtt
     6661 tggatatagt agatatcgtc gatgtttact ttatagactg ttttctgcgt ctgaataatc
     6721 atatatttca ttggattctc ctcctaagaa aagaataaca gaaaaggtct agcccaagca
     6781 cacccaatcc taaacagtct ttgaaaactc ctaaaaggat tattttctac aacatcatga
     6841 tgagcttaca actattttat cataaaattc actcagcgca attcaagaca tttcaatgac
     6901 aattaaagat ttgaataaaa aaaaagaatt aaaagtgata aactaacagt atcaaaacac
     6961 agttgccaga agtaagactg gcacccagat taaaggaggc attcccatga cagatacaga
     7021 ccccatcaaa agagctcata ctttgattac tgacttaaac aaagcctacc aagcatgcaa
     7081 acaggcaagc gctgacgacg tccgctttca ggagcaatta aactctattc ttggttttct
     7141 agccaaggct gaaacagtgg ataatcgatt cttgattgaa ctagaaaaat tttaccagac
     7201 ttccagtctt ctcatgggac tcagcgctct tgatccagat gctccaactc gcgccgcttg
     7261 gcgggcctat gaccgcttcc actttgacca agtcaagacc aagttaatac tcaatgaaaa
     7321 tcaaagagca aactaggaag ctagccgcaa gctgtacttg agtacggtaa gacgacgctg
     7381 acgtggtttg aagagatttt cgaagagtat aagtctctac ggaccaacca ttatcctgta
     7441 gtaacaaaaa agaagttgag acagactgaa ctcaacttct tttttagtgt cgtatcagca
     7501 atgttagtcc tgcatctgac gttttacctg ataaggcaaa tacaagacta gtaaaaccaa
     7561 accagctcct agtaaggcta gaagggctag tttttcttgg aaggtaatca acccaacaac
     7621 taattccaca agtaaaacaa aactggtcaa tcctcgaact acctcctgta agcctttttc
     7681 cttttgcccc ttgtccagcg gaaagagttg ggtcaaatac tggtagtcaa aggcatgata
     7741 gagggccagc aactggaaga gcaagaggta gttaaagaga actaccactg ctgtcgcaat
     7801 ccaagcttgc tcgataaaaa cctgcgccag tacggaaagt aagagaagac gaagactgag
     7861 agcaaagagg tcgccatttc gcagataaga acgcagatag agattttgcc aaatcttccc
     7921 aggcaccttc tgaacagcct ttaagataaa gtccagatag gcacgacgct taacgctgtt
     7981 tgaaattccc ttgacctgcg taaagagggc aaagaaacga agcaagactt gcttacgctt
     8041 gctttcttgg gaaatgacat agtcccaatc cagtccagtt tcagtgaaaa atttgctggc
     8101 cttttgacga aagtggaaat attttcctac ccccaataaa agcacataga gcagaaaaac
     8161 tggcaagcca taacccattg ctaaaaataa aggcgcaaat aacagcaaga aaagggtctg
     8221 tacaaagagc caaaagacta gggaaatgcc agtttgacgc ttgagatgga gcttgatttc
     8281 ctcttctcca actaagagaa agagcttgtc tggagcctcc atataggtgg caattcctcc
     8341 ccaaagtaaa agtaaaacag acgtaattcc tacaaacaaa aggataggcc aatgattttc
     8401 aggaaaatgt tgtaagagtt gactgtactg gtaggctaga aagcccaaca ggacaagcag
     8461 gaacaagaca aagtggtcat tgagcacata gcgcagataa ccaagacact ccttacgaaa
     8521 ggcctgcttt ctctttaaaa acaagtcttt cataggtcct cctcttttgt cagagccaag
     8581 taaatatcat tcaaactagc ctcaggcata tcaaaggctt cgcgtagttg caggagattg
     8641 cctttggcac gcacctctcc cttgtgaaga atgacaaagg catcacacat cttctccgcc
     8701 gaatccagca cgtgggtact catgagaata gacttgccct tttgcttctc cacttccaaa
     8761 agctgaatca aatcagaaat agccagcgga tcaagaccaa ggaaaggctc atccacgatg
     8821 aaaagacttg gatccgccac aaaagcacag ataatcatga ccttctgctt catccctttt
     8881 gaaaaatgaa cagggaacca gtctaatttc tgttccaaac ggaacatttt taacaagggc
     8941 tctactcgtt cgaaagccac tttttgctca ataccgtaag ccatagcaac cgtttcgata
     9001 tgctctctga gagtcaattc ctcatacaga ctaggcgtct caggaatgta gccaatctgc
     9061 ttgcggtagc tagtcgcatc tccttgcaga gtcaggccat tgatattgat ggagccacta
     9121 taaggtgcca acagaccgat aatctcattg atcgtcgttg atttcccagc accattgaga
     9181 ccaatcaaac cgaccaactg cccactttca acagtaaagg acacatcttt caaaacagga
     9241 acatgaacat agccacctgt caggttttta atttctaaca tattttctcc aaatctggta
     9301 taatgtagct atattatatc aaaattcagt acagtagagg tagattttat gtcagattgc
     9361 attttttgta aaatcatcgc aggggaaatt cctgcttcaa aagtatatga agatgagcag
     9421 gtccttgcct ttcttgatat ctctcaagta acactaggac acaccttggt cgtgccaaaa
     9481 gaacactatc gcaatctttt ggagatggat gctacgagcg ccagccaact ctttgcccaa
     9541 gtaccaaaag tagctcaaaa agtcatgaaa gtcactaagg ctgctggtat gaatatcatt
     9601 tccaactgtg aagaagtcgc tggtcaaaca gtttttcata ctcacgttca ccttgtacct
     9661 cgctacagtg ctgacgatga cctcaagatt gattttatcg cccacgaacc agactttgac
     9721 aaacttgctc aagtcgctga aaccatcaaa aacgcttaag gagttgctat gaaattatcc
     9781 aacctactgc tatttgcagg agctgcagcc ggaagttatc tggtcacaaa aaatcgccaa
     9841 accatcacag atgaagtctt gaataccact gaccgcgttc aagctatcaa ggacgatgtg
     9901 gatattatcc aaaacagcct gcaaatcatt gaccagcaaa aagaacttat caaggaatac
     9961 caagaagact tgacttacaa gtttaaggtc ttggaaaagg atatccagac tagactagct
    10021 gtgataaaag aaatgcaggg aactgaagat aagtaaaaag agcccgacgg ctctttttta
    10081 aaacgtaaac aagttatagt gaattgaatt tagaatagca catcatagtt tctaaagcat
    10141 tgttagagat tactttaaaa tcctcttatc aatttgttca tattctattt caatctacta
    10201 tatatatccc atcaactatg catcataatt taggtaactc atactcaata aaaatcaaaa
    10261 agcaaactag aaagctaggc acagactgct caaaacaccg ttttaaggtt gtggatagaa
    10321 ctgacgaagt cagtaaccat acccatgaca agccgacgct gacgtggttt gaagaaattt
    10381 ttgaagagta tcattcacca tttcacaact aaatcgaaga ctttctgccg taatgaaaac
    10441 acctgaaaca gcttggtttc ggctatccgg aaactttaag acttaggttc aaagtttagg
    10501 tatggaactt cgaaggaggt cgctaccgtc cgtcattact taggaaagtc ttaaaaaatc
    10561 tataaagtaa aaagagcccg acagctcttt ttgtttatac tcaatgaaaa tcaaaaagca
    10621 aactaggaaa ctagccacgg gctgctcaaa acactgtttt gaggttgtag atacgactga
    10681 cgaagtcagt cacatatata cggcaaggca acgctgacgt ggtttgaaga gattttcgaa
    10741 gagtattatt ctccatcaaa ggcatcttta atatggtcaa agaagccttt tttctttgga
    10801 tttactttca agtcaccagc agccgcgaat tctttcaagg ctactttttg gcggtcgttc
    10861 aagcctgtcg gtgttacgac attaacagta acgtattggt caccaactgc accgccacga
    10921 aggctcggtg cccccttact acgtaggcgg aacttcttac cagtctgagt tccctctgga
    10981 ataaccaatt caacatcacc gtgaacagtt ggaatatcta ctgtatcacc aagagccgct
    11041 tggacaaagt tgaggttgag attgtagaag atagtcgttc cttcacgttc aaacttgtcg
    11101 ctagcttcca cagaaactac tacatacaag tcaccataag gtccaccgtt aaagcctgct
    11161 tcaccttgac cagcgaggcg aatttgttga cctgtttcca caccagcagg gattttcaca
    11221 tgtacgctat gagcttgttt ctcatgacct gttccatgac aggttgtaca tggatatttg
    11281 atttcttttc ctcgaccgtg acagacatca caggttactt ggcgacgcat cataccaaga
    11341 ggagtctgcg tatcgacgtt aatgacacca gcgccatgac agcgtccaca agtgactgga
    11401 cttgtccctg gcttagcacc agatccatta catgtacgac agccagcttc acgatgatac
    11461 ttaacttcct tctcagttcc gaagatagct tcttcaaagg tcaaattgac acgatactgg
    11521 agatcatctc cttggcgagg agcgtttgga ttgcgcgaag aaccgcctcc gccgaagaaa
    11581 cttgagaaaa tatcctcaaa accaccgaag ccacctgccc cattgaaacc gccgaaacca
    11641 ccagctccac caaaaccacc attggcgcct gcagcaccat actggtcata ggcagcacgt
    11701 ttttggtcgt cactcaaagt ctcataggct tcttgaactt ccttgtactt gtcctcagca
    11761 ccaggctcct tgttgatatc tgggtgatat tttttggaaa gcttacgata agcctttttg
    11821 atttcgtctg ccgaagcgtt tttggatacc cccagacgat cataaaattc agtattgttc
    11881 ataattcaag atacaaaggg cgtcaaacgg acacagccat ctaggagttt tgacgacgga
    11941 cgcttacgtc ctagaaaaaa ctatcttttt ggcacagtcc atagcccgtg ttcagttacg
    12001 aacaccctta ttcctttcta ttgatgttct gaatcgaacc accatttagg tcgggttcaa
    12061 ttcctttctt ttatatttag taagaaattc tgaaacccgt gttcagttac gaacactctt
    12121 tgttcctttc tattgatgag acaaaaccca aacaaatgag attccgtccc tttttatcga
    12181 aaaacagagg ctgggttgca acctctgcaa ataagtaaat taactttatt ttgattttaa
    12241 atatcctata agtacagaaa tatttatata tttttgtctc ttcttagtat ttgcctatat
    12301 aattccaatt gatcataaga aatacaacta ctgtccaaat cataccaatt atgaacggta
    12361 ttacaaattt atatgtttgt atttctaatg atatcatagc tggtaccatc gccgatacaa
    12421 atgcagacaa caatactgag gtaacaaaat tccttaccgc ttcatcattt ttgatacaac
    12481 tatcatgttc agctaatata attctctata tctagctaaa tattctattg gaatattatc
    12541 aataaaatct tttgatgttc tatagttatc agcttgatta caaaaatcat tataaacttt
    12601 tcgtgtattt tttagatact cttcatccaa tacactcatc ttacttttcc gtaaactctc
    12661 cgtctacgac gtcatcgcct gcgttccctg ttgcttgtgc gccttctgct ccttcttgag
    12721 cttgttgcgc tgctgcggct tgttcgtaga gtttaacagc aagtccttga gctttttcgt
    12781 tcaatgcttc aagttttgtt ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa
    12841 ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc gaagccttta ccttcagttt
    12901 ccttgattgt cttttcagtc gcaaagattg cttggtctac ttcattacga aggtctactt
    12961 cttctttacg tttcttatcg gcttcagcgt ttgcttctgc atctttcatc atgcggtcga
    13021 tttcttcgtc agtcaaacct gagttcgatt ggatgacaat agtttgttct ttttgagttc
    13081 caaggtcttt ggccttaaca gacacgatac cgttcttgtc gatgtcaaat gttacttcga
    13141 tttgaggaat tccacgaggt gcagctggga tatcagtcaa ttggaagcgt ccaagagtct
    13201 tgttatctgc tgccattggg cgttcacctt gaagaacgtg gatatcaacg gctggttggt
    13261 tgtctgctgc tgttgagaag acttgtgatt tagatgttgg gattgtagtg ttgcgatcga
    13321 taagttttgt aaatactcca cccattgttt cgataccaag tgacaatggc gttacatcaa
    13381 gaaggacaac gtccttgaca tcaccagtaa tcacaccacc ttggatagcc gcacccatag
    13441 caactacttc atcagggttt actgatttgt ttggttcttt accagtttca gctttaacag
    13501 cttcaacaac ggcagggata cgagttgaac caccaacaag gataacttcg tcgatttctg
    13561 acaagctcaa acctgcatct gaaagggctt gacgaactgg aacttttgta cgttcaacaa
    13621 ggtcacgagt caaatcgtca aatttcgcac gagtcaaagt catttccaag tgaagaggtc
    13681 cagcctcacc tgcagtgata aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt
    13741 ctttcttcgc tttttcagcc gcatctttca aacgttgcat tgccatcttg tcagtagaca
    13801 agtcgatacc gttttctttc ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa
    13861 agtcgtcacc accaagtttg ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac
    13921 ccaattcaag gatagagacg tcgaatgtac caccaccaag gtcaaatacc aagatttttt
    13981 cttctttgtc agtcttgtcc aaaccataag caagagctgc tgcagttggt tcgttaacaa
    14041 tacgttctac ttcaagacca gcaattttac cagcgtcttt tgttgcttga cgttgagcgt
    14101 cgttgaagta agccggaact gtgataacag ctttggttac tttctcacca aggtagtctt
    14161 cagcgtagcc tttcaagtat tgaaggatca tagctgagat ttcttgtgga gtgtattctt
    14221 ttccatttgc agaaactttt tcagaagttc ccatcttaga tttgatagag ataactgtat
    14281 ctgggtttgt aactgcttga cgttttgcag catcaccaac gatgatttct ccgtttttga
    14341 atgagactac agatggagtt gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag
    14401 ttccttcaag aactgcaact gctgagtttg ttgtacctaa gtcaataccg ataattttag
    14461 acatgtgttt ttctccttgt tagttaattt tctatttttc tttttgatac tcttcttaag
    14521 tggcgacgcc gtcagagctt gacttcgtca atctctttga ctaaactttg agcctaaggt
    14581 ctcaaaattt gcgcaaatag cgccacggcg aagagtatcg tgtttggttc gcttcgctca
    14641 ctattacaaa gccaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    14701 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    14761 agtaaggaag ctaggcaaac gccatagcga ttgccgtttt ctgacgagtt gctttagcta
    14821 ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat agattttctt
    14881 gtgttcatcg aacacttcgt caatctccta tttttactgc gagcttttta cgggctttat
    14941 atcttagtta tacaccacta ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc
    15001 tttttgaaag acttgagcga tggtatctac tgggtgttca tcgtctgctg ggagagtttg
    15061 gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt caattccttc
    15121 ttctttcaaa gcgtgaatca agctttcttg caccatcccc aagcccttct tcacatcatc
    15181 tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta agattgcttt
    15241 tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcattgg cacggcgttg
    15301 gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat ctgcacgttc
    15361 atttgccaag tccaactcag acttttcagg agttgtttct tcagctgttt ccacaacttc
    15421 ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt tcgcctcctt
    15481 taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg gtaaaaatct
    15541 gtcaacttca tggtcaaaac acggttgacc acattgattt gattgattag ctgttggtaa
    15601 tccagattaa ctggaccgat aatggctaga attccaactc cccgataagg aatgaggaac
    15661 ttactactaa tcaccgctag gtcagctaaa caggactctt gaccgtctgc aacacgaaca
    15721 ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt ttgcggttgg
    15781 tcaaagaact gataggctgc tagattggca aaattcaaga gattgacctt gcccgccatc
    15841 acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat gacattatcc
    15901 gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt gtagtgaata
    15961 tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt cagcaaatcc
    16021 tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg
    16081 gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc tgtcaaacgt
    16141 tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc tgttagcaag
    16201 ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa ggctttgaca
    16261 atctcatata cctcattttc agccagtcgg tcaaaatcca gtgagtgttt cacatagtac
    16321 tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc aagcaaccct
    16381 tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt aatagactct
    16441 tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat aatcagattt
    16501 aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg atcaattagc
    16561 actcaatgca tccaagtgct aactcatgat tctattatac acccttagaa gagaatgtca
    16621 agacaaaaac tcaaaaaatt agcactcttt tatcaagagt gctaaaaatc aatctgaaga
    16681 cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat aaccatgaat
    16741 tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca tagaaagttc
    16801 ctctctaaac aaactcatac aaacaacaag accacctaag aaagtagctg tacaggaacg
    16861 aagtctagat cgcataactt cccatttgag ccccttactc atatagactt gatcctctgg
    16921 aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta tcaattccca
    16981 acctctatct ctaaattctt gcagttcatg cttatatttt ttaagaaatc tagaatcata
    17041 gatacggtag atgacatcgt ctggttgaca ttggtcaaaa tagaacaaac caaaacgact
    17101 cgttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt ccttgtccaa
    17161 atcaagaatg gtgaaaatcc gaaattctac tctgctattc attgtcttac cccaaaatta
    17221 gaaaacatgc ctggcgttat ttattagata attctttcca cttttgactc aatctccaaa
    17281 aaatataaga aatctgaatc gcaaaaacta tcaataaaac acaatctatt atgaaaatca
    17341 aaaatactcc tcaactgaaa gaactacctc cagtgacaaa ctttgagaaa accggtagta
    17401 gagctaaaaa gagaagcaaa ataggaagca tccgcattgt taaaatccgt ttggcataaa
    17461 aaatctttat ttaaactaaa atattatagc aaaatttacg ccagtttttg aacggctgat
    17521 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    17581 accagcccga ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacatcggaa
    17641 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    17701 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    17761 tagtttattt tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt
    17821 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    17881 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    17941 ggtcgaattg aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    18001 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    18061 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    18121 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    18181 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    18241 aaaggattga cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    18301 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    18361 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacagggaa aacgttcatg
    18421 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    18481 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaagcc attcgaaaag
    18541 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttctttcgaa
    18601 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    18661 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    18721 aaggaaaaca gtaactggcg taaggtaatt gattatttca gttctgcgac acagattggg
    18781 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtgagcca
    18841 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    18901 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    18961 gctaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    19021 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac
    19081 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    19141 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    19201 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    19261 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    19321 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    19381 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    19441 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    19501 ctggaaacag gtgcgaaaac agtcagtggt tctacgcccg gtttcgtaga tgaggaaggt
    19561 gacccagtag aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    19621 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcggaag
    19681 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcggat
    19741 aaaaagaagc ttatcttaga cgaactttat aaaaaaggag tttatctaga tgctattcga
    19801 gagtcggagg gaatatcaga acaagaaatc gatgattttg atttactcct aaaacttgcc
    19861 tatggtcaaa aagaattaac caaaacggaa cgtatcaata aactcaaaca aagcggatat
    19921 ttatataaat atagtgagga agcgcgtgct gttttggaaa ttttactgaa caaatacatg
    19981 gataaaggta ttggagaact cgaaagcatt gaaacattaa aacttccaga atttcagata
    20041 tatggtggaa ccttcaaaat catcaatact tattttggag ataaaaaacg atatttacaa
    20101 gcaattaaag aattggagca agagctattt acagtagctt aatgaaagga aagtatgtca
    20161 attacatcat ttgtaaaaag aattcaagat atcactcgaa acgatgctgg tgttaatggt
    20221 gatgctcaac gtattgagca aatgtcttgg ttattattct taaaaattta tgatagccgt
    20281 gaaatggttt gggaattaga agaagacgag tatgagtcaa ttatcccaga ggaattaaaa
    20341 tggcgaaatt gggctcatgc tcaaaatggg gaacgggtat tgacaggcga tgaattactt
    20401 gattttgtca ataacaagtt attcaaagag ttgaaagagc ttgaaataac ttcaattatg
    20461 cctattcgaa aaacgattgt taaatcagct tttgaagatg cgaacaacta tatgaaaaat
    20521 ggcgtcttgt tacgccaagt catcaatgtt attgatgaag ttgatttcaa tagccctgaa
    20581 gatcgtcatt cgtttaatga tatttacgaa aaaattctta aagatattca aaatgctggg
    20641 aactcaggag aattttatac gccacgtgca gcgactgatt ttattgccga agttcttaac
    20701 ccaaaacttg gagaatcaat ggcagacctt gcttgcggaa caggaggctt cttgacttcg
    20761 actctgaacc gtttaagtag tcaacgtaaa actagtgaag ataccaaaaa atataataca
    20821 gctgtttttg gtattgaaaa gaaagcattt cctcatcttt tagcagttac aaatctgttt
    20881 cttcacgaaa ttgatgaccc taaaattgtt catggaaata ctttggagaa aaatgttcgt
    20941 gaatatacgg atgatgaaaa atttgacatt attatgatga atccaccttt tggagggtca
    21001 gaattagaaa caataaaaaa taactttcca gcagaattac ggagttctga aacagctgat
    21061 ttatttatgg ctgtcattat gtatcgtttg aaagaaaatg gtcgtgttgg agttatttta
    21121 cctgatggtt ttctatttgg tgaaggtgta aaaactcgct tgaaacaaaa actggtagat
    21181 gagttcaact tgcatacgat tattaggttg cctcatagtg tctttgcacc gtatacagga
    21241 atccatacga acattctttt ctttgataaa acaaagaaaa cagaagaaac ttggttttat
    21301 cgtttagata tgccagatgg ttataaaaat ttctcgaaaa ctaagccgat gaagtcagaa
    21361 cacttcaatc ctgttcgtga ctggtgggaa aatcgtgaag agattctgga aggtaagttc
    21421 tacaaatcta aatcatttac acctagtgaa ttggctgagt tgaattataa tttagaccag
    21481 tgtgactttc caaaagagga agaggaaatc ttaaatccct ttgagttgat tcagaattat
    21541 caagcggaaa gagcaacttt aaatcataag attgataatg tattagctga tattttgcag
    21601 ttgttggagg acaaataatg acaccagaac aacttaaagc aagtattctc caaagagcga
    21661 tggaagggaa attagtgccg caaaatccca atgacgaacc tgcaagtgaa ttattaaaga
    21721 gaattaaagc tgaaaaagaa aaacttatca gtgaaggaaa aatcaaacga gataaaaagg
    21781 aaactgagat atttcgtggt gatgatg
//
LOCUS       DAVLTG010000034        21803 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLTG010000034 DAVLTG010000000
VERSION     DAVLTG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.034"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..1026
                     /locus_tag="VYN12_001377"
     CDS             <1..1026
                     /locus_tag="VYN12_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1415755.1"
                     /translation="MPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQ
                     KLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSFIA
                     QDFNNLNIITVLEGRTQAVIRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIV
                     QHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKQFYRPTFRMHLTN
                     KEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTF
                     LKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSRA"
     gene            complement(1126..2748)
                     /gene="groL"
                     /locus_tag="VYN12_001378"
     CDS             complement(1126..2748)
                     /gene="groL"
                     /locus_tag="VYN12_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1415756.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2764..3048)
                     /gene="groES"
                     /locus_tag="VYN12_001379"
     CDS             complement(2764..3048)
                     /gene="groES"
                     /locus_tag="VYN12_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1415757.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3318..3713)
                     /locus_tag="VYN12_001380"
     CDS             complement(3318..3713)
                     /locus_tag="VYN12_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1415758.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3790..4551)
                     /locus_tag="VYN12_001381"
     CDS             complement(3790..4551)
                     /locus_tag="VYN12_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1415759.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(4584..5210)
                     /locus_tag="VYN12_001382"
     CDS             complement(4584..5210)
                     /locus_tag="VYN12_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1415760.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPVKHWTA"
     gene            complement(5226..5543)
                     /locus_tag="VYN12_001383"
     CDS             complement(5226..5543)
                     /locus_tag="VYN12_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1415761.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5540..5839)
                     /locus_tag="VYN12_001384"
     CDS             complement(5540..5839)
                     /locus_tag="VYN12_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1415762.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            5927..6007
                     /locus_tag="VYN12_001385"
                     /pseudo
     CDS             5927..6007
                     /locus_tag="VYN12_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6136..6327)
                     /locus_tag="VYN12_001386"
     CDS             complement(6136..6327)
                     /locus_tag="VYN12_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1415763.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6488..7162)
                     /locus_tag="VYN12_001387"
     CDS             complement(6488..7162)
                     /locus_tag="VYN12_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415764.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKIVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(7168..7614)
                     /locus_tag="VYN12_001388"
     CDS             complement(7168..7614)
                     /locus_tag="VYN12_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415765.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7728..8231)
                     /locus_tag="VYN12_001389"
     CDS             complement(7728..8231)
                     /locus_tag="VYN12_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1415766.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(8228..8590)
                     /locus_tag="VYN12_001390"
     CDS             complement(8228..8590)
                     /locus_tag="VYN12_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1415767.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8656..10515)
                     /locus_tag="VYN12_001391"
                     /pseudo
     CDS             complement(8656..10515)
                     /locus_tag="VYN12_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(10554..11003)
                     /locus_tag="VYN12_001392"
                     /pseudo
     CDS             complement(10554..11003)
                     /locus_tag="VYN12_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(11127..11843)
                     /locus_tag="VYN12_001393"
     CDS             complement(11127..11843)
                     /locus_tag="VYN12_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1415768.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12724..14139)
                     /gene="ply"
                     /locus_tag="VYN12_001394"
     CDS             complement(12724..14139)
                     /gene="ply"
                     /locus_tag="VYN12_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1415769.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(14150..14482)
                     /locus_tag="VYN12_001395"
     CDS             complement(14150..14482)
                     /locus_tag="VYN12_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415770.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTGIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(14553..15161)
                     /locus_tag="VYN12_001396"
     CDS             complement(14553..15161)
                     /locus_tag="VYN12_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415771.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(15174..15632)
                     /locus_tag="VYN12_001397"
     CDS             complement(15174..15632)
                     /locus_tag="VYN12_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1415772.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15757..16153
                     /locus_tag="VYN12_001398"
                     /pseudo
     CDS             15757..16153
                     /locus_tag="VYN12_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16894..17154)
                     /locus_tag="VYN12_001399"
     CDS             complement(16894..17154)
                     /locus_tag="VYN12_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415773.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(17213..17764)
                     /locus_tag="VYN12_001400"
     CDS             complement(17213..17764)
                     /locus_tag="VYN12_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415774.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17754..17951)
                     /locus_tag="VYN12_001401"
     CDS             complement(17754..17951)
                     /locus_tag="VYN12_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415775.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17955..18539)
                     /locus_tag="VYN12_001402"
     CDS             complement(17955..18539)
                     /locus_tag="VYN12_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415776.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(18947..19372)
                     /locus_tag="VYN12_001403"
     CDS             complement(18947..19372)
                     /locus_tag="VYN12_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415777.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(19500..19883)
                     /locus_tag="VYN12_001404"
     CDS             complement(19500..19883)
                     /locus_tag="VYN12_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415778.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            complement(19905..20111)
                     /locus_tag="VYN12_001405"
     CDS             complement(19905..20111)
                     /locus_tag="VYN12_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415779.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISRVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(20098..20259)
                     /locus_tag="VYN12_001406"
     CDS             complement(20098..20259)
                     /locus_tag="VYN12_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415780.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20631..21587)
                     /gene="lytA"
                     /locus_tag="VYN12_001407"
     CDS             complement(20631..21587)
                     /gene="lytA"
                     /locus_tag="VYN12_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1415781.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
BASE COUNT         6489 a         4869 c         3758 g         6687 t
ORIGIN      
        1 atgcctacta gaattctcct tagaaagcgt cgattcaagt gttatcactg ttcaaaaatg
       61 atggtcgctg aaacttctat cgtcaagaag aatcaccaaa tccctcgtat tatcaaccaa
      121 aaaattgcgc aaaagttaat tgaaaagatt tctatgaccg atattgccca tcagctttcc
      181 atctcaactt caactgttat tcgtaagctc aatgattttc actttaaaca tgatttttct
      241 tgtcttcctg agattatgtc ttgggatgag tatgctttta caaagggaaa gatgagcttc
      301 attgcgcaag attttaacaa tctcaatatc atcactgttc ttgagggaag aacacaagct
      361 gtcatccgag atcactttct taaatatgat agagccgtcc gatgtcgcgt caaaattatt
      421 actatggata tgtttagccc ttactatggc ttggctaaac agcttcgctt tcacattgta
      481 caacatctta gccgtgctat gagtcgtgtg cgtgtccaaa tcatgaatca gtttcatcga
      541 aaatcccatg aatacaaggc tatcaagcgc tactggaaac tcattcaaca ggatagccgt
      601 aaactgagtg ataagcaatt ttatcgtcct acttttcgta tgcatttaac caataaagag
      661 attttaaaca agcttttgag ctattcggaa gacttgaaac atcactatca gctctatcag
      721 ctcttgcttt ttcacttcca gaataaggaa ccagagaaat ttttcggact tattgaggac
      781 aatcttaagc aggttcatcc tatttttcag actgtcttta aaaccttcct caaagataaa
      841 gaaaagattg tcaacgccct tcaactacac tattcaaacg ccaaactgga agcgaccaat
      901 aatctcatca aacttatcaa gcgcaatgcc tttggttttc gaaactttga aaacttcaaa
      961 aaacggattt tcatcgctct gaatatcaaa aaagaaagga caaaatttgt cctttctcga
     1021 gcttagcttt tcttcaaccc actacagttg acaaagagcc tataaaaaga agggttagtc
     1081 attccctcct tttgtgtttt ttataagttg ttttctatag aaagcttaca tcatcccgcc
     1141 catcatactt ggatccattg ctggagctgg ggctactggt tctggtttat tggctacgac
     1201 tgcttctgtt gtcaaaatca agctggctac agatgctgca ttttgtaggg ctgaacgact
     1261 cactttaact ggatcaatga taccttgatc aatcatgtta acccactcgc cagttgctgc
     1321 gttgaatcct ataccaagct cagcattttt caaacgatcg ataacgatag atccttcaaa
     1381 tcctgcattg tgagcaattt gacgaacggg ttcttccaaa gcacggagaa caatattacg
     1441 tcctgttgct tcatctcctg tcaattccaa ggtagcaaca gctggaatca cattggcaag
     1501 agctgttcca ccacctgcaa caataccttc ttcaacagct gcacgagtag cgttgagggc
     1561 atcttcaatg cggagtttca tttctttcaa ctcagtttca gttgcggctc cgaccttaat
     1621 aaccgctaca ccacctgaca atttggccaa gcgttcttgc aatttttcac ggtcaaattc
     1681 agaagttgta gtttcgattt gagacttgat aaccgcaaca cggttagaaa tcgcttcagg
     1741 atttcctgca ccttctacaa taaccgtgct atctttgtcc acggtcactc tcgctgcttg
     1801 accaagagct tcaattgtcg catctttcaa ctcaagacca aggtcttctg tgataactgt
     1861 tccgcctgtt aagatggcga tatcttcaag catggctttg cgacggtcac caaaaccagg
     1921 tgccttgact gctactacgt tgaaggttcc acgaatcttg ttcaaaacaa gagttggaag
     1981 agcctcgcca tccacatcat ccgcaataat caagagtgga cgattgcttt ggagaatgct
     2041 ttccaaaagt ggcaagattt cttggatatt ggaaattttc ttgtctgtaa tcaaaatgta
     2101 cggattttca aggtcagcca ccattttttc gctatcagtc accatgtact gtgaaaggta
     2161 accacggtca aactgcattc cttctacgac ttcaagctct gtttccatac cacgtgactc
     2221 ttcgatggtg atgacaccgt ctttgccaac tttttccatt gcttcagaga tgtactcacc
     2281 aactttttca gaacgagaag atacggctgc aacttgagcg atagcttctt tattggcaac
     2341 agggatggcg ttgtttttca aagcttcaac tgctgcggca actgctgttt caatcccacg
     2401 acgaataccg attggatttg cacctgctgt gacgtttttg attccttcac ggacgatagc
     2461 ttgggtcaag actgttgcag tcgtagtccc gtcacctgcg atatcattgg ttttagaagc
     2521 tacttctgat actaacttag cacccatatt ttcaaaatgg tcttccaatt cgatttcttt
     2581 ggcaatggtc acaccgtcat tggtaatcaa gggtgaaccg aatgactttt caagaacgac
     2641 attgcgacct tttggtccca aggttacttt aacagtgtct gcaagaatat cgacaccacg
     2701 aaccatggct gaacgggcat ctgatgaaaa tttaatttct tttgacatac ttactttctc
     2761 cttctattcc tcaatgattg ccaaaatgtt agcttcgcct acgataatgt acttttcatc
     2821 gccatctttg acatcaagac ctgcgtgggc ttcaactaag acacgatctc cagttttaac
     2881 acttggagca accaagtcac cgttcaaggt acgaacacct tgtccagtag ccacaacttg
     2941 agctgttttg gttttttctt gggctgagcc tgcaaggaca aagcccccaa cggtttgttc
     3001 tttttcttct atttttaaga ccacacggtc ccctaatggt ttcaacatct gatttcctcc
     3061 ataatgagat agatattatt agcactcttt gaactggagt gctaattcat aattctattg
     3121 tatcacttgg tcagaaatag tcaagaaaaa agtctgactt tctcaagata aaaagcctga
     3181 gaccaactca gactttttaa tgtttatact caatgaaaat caaagagcaa actaggaagc
     3241 tagccgcagg ctgctcaaag cattgctttg aggttgtgga taaagctaac gtggtttgaa
     3301 gagattttcg aagagtatta aaatggcaat tcttcctctt ccaagaccaa atctgccaaa
     3361 tcttggcctg cattattttc acgcatggca cgttgagcac gactttctaa gagttggaat
     3421 cctgtcacaa ggacttcggt tacatagttc atctgaccat ttttctcaaa gcgacgggta
     3481 cgcaattctc catcaacgga aatgagacta cctttggttg cgtagcttgc caaagtttct
     3541 gctagtctgc cccataggac catattgaca aaatcagctt cacgttcacc gttttggtct
     3601 ttgtaacgac ggttgacagc gatagttgct cgcgctaccg acttgtcatt gttggttttg
     3661 tgcaattctg gtgtagacgt taaacgccca atcatgataa ctttattata catattttct
     3721 tcctcctact tatctattcg taggaaatca aaaaagttac agaaatttgt aacttttcga
     3781 ggaaatttct tattttttat gaatcatgaa acctgtcgcc tgttgattgg ccataatggt
     3841 catatctgta atctgaacac ggcgaggctg actggtcaca tagactactg tgtctgcaat
     3901 atcctgagct tgcaaggctt ctattccttg gtaaacggac gcagcccgct ctttatcacc
     3961 atgaaaacga acagttgaga aatctgtttc gacaatccca ggctgaatgg ttgtcacctt
     4021 gatatccgtt gcgatggtat caattcgcag tccatccgaa aaggtcttaa ccgctgcctt
     4081 ggtagctgag taaacagcgg caccagcata ggcgtagatt cctgcggttg accccatatt
     4141 gataatatga ccttgattga cttttatcat tgctggcaag aaacagtgag taaccgccat
     4201 cagaccttta acattggtat ccaacatggt caacatatcc aactcctcat agtcttgata
     4261 gggagccaag tcaagagcca gtccggcgtt gttgaccaag atatcaatcc tccctatcgt
     4321 ttctagaata tcagagcaaa cagtcttcac catgaccata tccgtcacat ctagtggaaa
     4381 agtccagacg gtttgatttg gaaagcttac tgcaaactcc gacttgagga tttctaatct
     4441 gtctatccgt cgtcctgtta gaacgacatc ctcaccctgc tccagataag cacgcgcaat
     4501 cgcttcaccg attcctgagg ttgctcccgt aatcactaca ttttttgcca tcttatttcc
     4561 ttctatcaga tgctgacaag ttcctaggca gtccagtgtt tcactgggtc gaacggtgtt
     4621 ccgacaactt ggtcttctga taattcaagc accccacgtt tttgcggagc atttggcaaa
     4681 tgcaattcac gaggactaca catcatccca aaactctttt caccacgaag ttcgcctggg
     4741 aaaatgaaat tcccttttgg catcatggca ccaggaagag ccacaatggt tttcaaccca
     4801 acacgcgcat taggtgctcc tgcaacgatt tgcactatct tgtcacttgc gactgcaact
     4861 tggcagatgt tgaggtggtc actatctgga tgggctacca tctcaacaat ttcaccaaca
     4921 acaaacttag gttccttgtc attgacaatt tcttctgtaa aaccttccgc ctgtaattct
     4981 tggttcaaac aagcgacttg ctcatctgat aaaaagactt gacctcgctc tgcaatttca
     5041 aacaagctcg aaacctcaaa aatgttccaa gctactgttt ccccattttc tttgaggaaa
     5101 acacgggcta ccttgccttt gcgttccaca ttcagtttgg catctccgct atttttcacg
     5161 atgaccataa ggacatcacc gacatgttct ttgttatatg taaaaatcat tgtttacttt
     5221 ttctcctatt tcaatcctgc taaaaaatcg ttaatttgct ccttactttt acggtcgcga
     5281 ttgacaaaac ggccgatttc cttgtccttt tctagaacaa caaggctagg aattccgtaa
     5341 acatcccaga gtttggccaa atccatatac tgatctcggt ccattcgaat aaaggtgaac
     5401 tctggattgg tctcctcaat ctctggtaag gcaggataga tataacggca atcgccacac
     5461 cagtccgcca caaaaaggaa gaccttctta ccgtcttttt ctactaaaga tgccaattct
     5521 tctaaacttg ctggttgtat cataagactt cctcctcata gactaggtct tcattttcat
     5581 agacaaaagt ataatgacgg ccatcctcaa aaatgacgcc accaagcaag ctctctagac
     5641 tgctttcata gacttgaaca tagagggtcg caatttcccc catgtctgaa aaatggtctc
     5701 gtacaatcgc tgtcaactct tcctgagtct tcatgagctt atggtcatct gcaacttttt
     5761 tcgtagcaag ggcaaggctc ccaataccaa gcagagccag acctgccatc cacatttttt
     5821 tagctttcat accattcatt ttaacacaaa aaaggcttta ggacaaatga ggaaacagca
     5881 aaaaagcaag taaaaagcct cttcctttaa ggaaaaggac ttcttatact caatgaaaat
     5941 caaagaccaa actagaaagc tagccgcagg ctgctcaaaa cacggttttg aggttgtaga
     6001 taaggcgacg ctgacgtggt ttgaagagat tttcaaagag tattattctt attgccaggc
     6061 acctaagttg ccaacgtagt aaccatcagg tgtgtaggta ttgcgaagca tcttacctga
     6121 tgaagccaga taatactact tgccattgtc tttgacccaa tcattcgcaa tcatggaacc
     6181 agaagaactt acataatacc attctccctt gtcataaacc caagtactga ctttcatggt
     6241 tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt cgttttttaa aagcatttga
     6301 cactacatca tctacgctgt agtacataga tacatcaaac gtaaaagcca aaatatcgaa
     6361 aaatatacaa cttttaaagg cagcatttca ttttttaaag tctaacaacc atagaactga
     6421 aatcagagca aggcatcaat ttcctactct tagtacgtct attttgatgg ttgaagtgaa
     6481 gattttttta tttaacgtag acaatttcca acttcccaaa agccacatct ccacggatag
     6541 tcaaggtttt gctggttggg gctacaggag cgtcagcctt agctgcacca aaggaggttt
     6601 ctactttcaa atctacacgc cagtgttgtg gaacatagac ggttgcattt ccgaaggcca
     6661 cttcaatatt taaagttgca aaatcaccta gcatctctgc attatcatag tagattttag
     6721 catccccaaa agcgacttcc acttggtcat ctacgagatc ttgatcttgc ttatagaagg
     6781 tcccgctacc aaaagcgact tccttatccg tgacgactat ttttttccca ttgtaccacc
     6841 attttttttc attccagaac ttacttgaat gcgtcagata accaacacca agtaccacca
     6901 agatgctagc ccaaataaga gaatgattgg taactggtaa caagtcataa gcgtaatttg
     6961 caatgatgag cgccagtaaa cctgtaaaaa ctgccgaagt gagatgacgt ctaaggatgg
     7021 actcaatgga cttataagca aaaaaaacaa tacctagtaa aggccatatt ttaccatcca
     7081 aagaaggaat tccaaaattc ccttgcagca agatccaagc tgctaaaacc aataaaacaa
     7141 taccaaatgc tttctttttc atgtttttta cctcatgttt cttagatttt cttttaggag
     7201 ggattggtaa tgccgtgaga catgaacctc cttgtgcgtc tgataaaagg aaatggtgcc
     7261 cgttcctgaa aaggacttgt ccactgagta aatctgacgg atgtttgcga tcgttgactt
     7321 ggaaactcga ttaaaatagc gaggcaagat agactccaac tcatagagct tgaggcgaac
     7381 ctcataagct tccttctggt tatgagcgta gatcttgctc ccttctgttt caaagaagag
     7441 aatttctgac aggtctagat aatattcacc tgtccccttg taaaaagtca acctcggagc
     7501 ctttgactct tgcaagagcc gttgcaagtc tgcaatttca tctgtcaaag tgggggtctt
     7561 gatgacaatt tcagtctcct ctaaattgcc gtcaatctca attcgtaact tcatcacatc
     7621 tcctttctga ctctactata tcaaagctaa gttaggaata caagggcaaa aaagcaagtg
     7681 gtcaatttga agcagtaagt ggttgtagga ctagcttaac ttacatgtca gaataggaag
     7741 aaaaggaatc cccacaccaa accacaagca tagccaacca agacatcctt gggataatga
     7801 acacccccta aaaccctcac caaccccagc aaagctgaaa agatcaagca tactaagcca
     7861 ataggtagac tagcatgcag acaggccatg gagatgatag ttgccgaaaa gacatggcga
     7921 ctgggcatcg accgtcccga actatcctta tcaagaaggg gacagatatc ccaagtttca
     7981 taaggtctcg ggtgattgat tttcttacga aacagggaca aggtcacaaa acctgatgca
     8041 ggaataagca cataaacccc aacttgctga ccaagtccta gttgcaggta agtggtgact
     8101 agcaagatca gatagaccag gggcatggcg actgtcatca aacgattgaa actgcgtaat
     8161 aggaataaaa gaattggacg actagttagt ctggagctga tatttcgata ccattcttga
     8221 taatttttca tttatgcttc tcatactttt ctagaacttg ttgagatgtt ttccccttgg
     8281 caagccaatc cactagcttg tccaagcgac gtatttcctg catcagagga tcatcaattt
     8341 cctcaatacg gacaccgcaa atcttccctg taattgcaat tcgttcaggg acataatatg
     8401 gtgcttgtct aaaaaaatct ccgtaagtaa catccctatc cagacaagca agaacatcac
     8461 tcacttcata ccctgtcaac caactggtca cttggtgaac tgactctgcc tttccaccct
     8521 ttcgctcaac ttttgcaatc aaggctaagt agacagcagc aaatttcata ttgtataatt
     8581 tctgactcat acttctctct ttctatgtgt actagtataa ataagaaaaa gaaggccgtc
     8641 aagccttctt ttgatttatt cttctgcttc atcttctgta aattgactat tgtacaagtc
     8701 agcgtagaag ccaccttgcg ccatcagttc ctcatagttg ccttgctcga tgatatttcc
     8761 atctttcatg accaagatca agtctgcatt tcggatggtt gacaagcggt gggcaatgac
     8821 aaaggatgtg cgtcattcca tcaaacggtc catggctttt tggatcaatt cctctgtccg
     8881 tgtgtcaaca gaagaagtcg cctcatccaa aatcaaaagc ggtgcatcct taagaagggc
     8941 acgagcaata gtcaatagtt gtttttgtcc tacagacaag gtcacggtgt catccaagat
     9001 ggtatcatag ccatctggca aggtcataat aaagtggtga attcccacag ccttactagc
     9061 ttccatcatt cgttcatcac taatccctat ttgattatag atgagattgt ctcgaatagt
     9121 tccttcaaag agccaggtat cctgcaagac cattgaaaag gcatcatgca cttctgaacg
     9181 cgtcatagcc ttggtatcca caccatcaat gtgaatactt cccttatcaa tctcatagaa
     9241 tttcatcaaa agattgacaa tggttgtctt accagtccca gtcggcccaa caatggcaac
     9301 cttttgacca gcatgagctg tcgcagagaa gtcatagtct tgaacattga caccgtccac
     9361 cagaatttct cctgctgaca cgtcgtagaa acgtggaatc agattgacca gagttgattt
     9421 accagaacct gttgacccaa taaaggccac tgtttgacca gtttctgctt taaagctaac
     9481 atgttcaata actgcctccg aatttgccgc atagcggaag gtcacatcct taaactcgac
     9541 ctgacctttg aagttttcat cagtcagctg cacttgaaca gggttttgga tagaagaatg
     9601 caaatctaaa acttgattaa tccgcttagc agagaccata gttcggggaa gaacgatgaa
     9661 gagtgctccc atgagaagga agcccatgac aacctacatg gcataagaca tgaaaacaat
     9721 catgtcacta aagagaggca gacgcgctat cgaagcagcg tcgttaatca cataggcccc
     9781 aatccagtaa atcgctacac tcaaaccact tgaaatcccc atcatgatag gattcaaaat
     9841 agccataaga cggttgacaa acaaattcaa acgggtcaat tcatcattta ctgctgcaaa
     9901 tttttcattt tgataatcct ctgcattgta ggcacgaacg acacgaatac ctgttaaact
     9961 ctcacgagtg atactgttca gtttatctgt caacccctga atcaaggact gttttggaaa
    10021 ggctagcgtc atcaaaacgg tcgtcatcag gacgttgaca atcactacca caagtacggc
    10081 ccagagtcag tattctgaat gacctaaaat cttcccaata gcccagatag ccataattgg
    10141 accacgcgtt accacttgca agcccatagt aatcaacatt tgaacttgag taatgtcatt
    10201 ggtagtacgc gtcaagaggc taggaattga aaatttctta atctctgtct gcgagtaatc
    10261 caaaactcgg ttaaaaatat cacttctcag cctactagta taagaagccg ccactcggga
    10321 tgcaaaaaat ccaactgcaa ctacggacaa gaaggcaaga aagagcattc ccatcatcat
    10381 gcttgccggc tgccacaact catctaaatt agtttcttga ctacctagca aatccgtaat
    10441 tttcgagata taggtcggca cttccaactc tagatagacc gaaaagcaag taaagagaat
    10501 ggctagtaaa atcatccccc attcttttct actaattctt ttggttaatt tctttattct
    10561 ctcctcctat tcccttgata ttttgcctgt agttgaccga gaactttctc aaaaatcagt
    10621 aattcatctt catcaatgtc ttccatcaac tgcttgtcta tgcgttcaaa aaaagcctta
    10681 acctgttgca tctgagaacg tgctttgtcc gtcagacgaa caaacttagc ccgcttatca
    10741 acaggactcg cctccaattc caccaaacca ttttgcacta tacgcttaac cagattacta
    10801 gcaacagact tggtaatatt gagttcctgc tcgatatctt taatcaagac caagtcttgg
    10861 tttttctagc gattatccaa aaaacgcaca acctgacctt gcggcccacc cataaattca
    10921 atgccgcaac gtttggcttc cttttgcacc atcaggtgaa tttgatgacc aaaacgctta
    10981 aagactaaca tcggtttatc cataatctcc cccttctaaa taaaaatagt tctctggaga
    11041 ataattaaat ttctatgaga actattttct tgattaaaaa aatcccaagt gattttctca
    11101 cttaggatca tgttctatag gttaaattaa aacccatcta cgttcgtata aatcttttgg
    11161 acgtcttcgt cgtcttcaag aacgctgtaa agtttttcaa aggtttcaag gtcttcgcct
    11221 gacaattcca cttctgactg aggaatcatt tccaattcag tcacttggaa ttcttcaata
    11281 ccagactcac ggagagcaac gatagccttg tgaaggtcag ttggcgctgt gtaaactgtg
    11341 attgtacctt cttgtgcttc tacgtcatcc acatccacat ccgcttcgag caattgctca
    11401 aagactgcgt ctgcatcttc acctccaaat acaataacac ctttgttgtc aaagaggtaa
    11461 gaaacagaac ctgaagcgcc catgtttccg ccgtttttac caaaggctgc acggacattg
    11521 gctgctgtac ggttgacgtt agaagtcaaa gtatccacaa ttagcataga gccatttggc
    11581 ccaaaacctt cgtaacgtcc ttctgtaaag gtttcgtctg tgtttccttt ggctttatca
    11641 atcgctttat cgataatgtg ttttggcact tgggcttgtt tagcacggtc gataacgaat
    11701 ttcaaagctg agtttgattc tggatctgga tcaccttttt tagctgctac atagatttct
    11761 acaccaaatt ttgcatatac cttagagtta gctccatctt tagccgtttt cttggctacg
    11821 atattggccc atttacgtcc cattaggaat ctcctttttt cacattttaa tctttattat
    11881 tataacacaa gtttttttga ttttcactag aggaaatgga ttttattagc aaatcaagct
    11941 aggatagcac tttacctgct aagatggtct tacctttcta tctttatcaa cagacactca
    12001 tccacattca aaaaacaaac tagaccatta tctgcaaata gaaagtttca gccaagtttg
    12061 acaaagtcag ctcaaattac tgtttgaagt ttgtagatat aagcgacaaa aacaatcata
    12121 ctgcaccttt tgttgacagt ctactccaga catatcatag ttcaagtaaa tactttgaaa
    12181 ttcaacagtt cttataggcg ctattgtatt ctaagaaatc aatagaagag tttctaagca
    12241 aacctctaat actcaataaa aatcaaagag caaaccagaa agctagccgc aggttgctca
    12301 aaacactgtt ttgaggttgc ggatggggct gacatggttt gaagagattt tcgaagagta
    12361 taatttacgt gttcccaaga tggagaagtt agactagtac actggcactt ctaaaccatt
    12421 gctagcaatt gatttgttca tatttaattt cattttttcc ataaatgggt attagatata
    12481 aacagcaaaa tatttccgat acgtgtcgtt cttgaatttc caatcatcta aaacaagtaa
    12541 aggataatca atcccctgta tatcaaggaa ttggctaccc tttttacttt tttacacatt
    12601 ctgtttgata gattcatttt aacatcacga gcatactcca atggaaatcg ctaggcaaga
    12661 gataaacttt cagatatccg cagagagatc atcgcctctt tttgtcgcaa gcattctcct
    12721 ctcctagtca ttttctacct tatcttctac ctgaggatag agagttgttc cccaaataga
    12781 aatcgtccgc ttacgcacta gtggcaaatc ggttttttca taaaccgtac gccaccattc
    12841 ccaggcaagc ccggtacact ctctaatttt gacagagaga ttacgaacat tcccttttaa
    12901 aggaatacta gtggtaaagt gagccgttaa atcctgccca tttctgtccc aagccttagg
    12961 agtcaagact tccttacctt gatgatcata ggataattca ttccaagtaa tataatattg
    13021 ggcaacatag gcaccactat gatccagcag taaatctccg tttctgtaag ctgtaacctt
    13081 agtctcaaca tagtctgtac tattttgaaa ggtcgcaact acattgtcac gtaaaaaaga
    13141 agttgtatag gaaatcggca agcctggatg atctgctgta aagcgactgc cttcttgaat
    13201 caagtcctct accatatcca ccttgcctgt tacaactcgg gcacccgaac ttgggtcgcc
    13261 ccctaaaata accgccttca cttctgtatt gtccaaaatc tgtttccact ctgtctgagg
    13321 agctaccttg actcctttta tcaaagcttc aaaagcagcc tctacttcat cactcttact
    13381 cgtggtttcc aacttgagat agacttggcg cccataagca acactcgaaa tatagaccaa
    13441 aggacgctct gcagaaattc ctctctgttt taaatcctct accgttacag tatcttgaaa
    13501 cacatctcct ggatttttaa cagcatctac gctgactgta taataaatct gcttaaaatt
    13561 aacaatctga atctgctttt cgcccgaatg gacagagtta aaatcaatat caagagaatt
    13621 ccctgtcttt tcaaagtcag aaccaaactt gaccttgagt tgttccatgc tgtgagccgt
    13681 gattttttca tactgcattc tagctgggac attattgacc tgaccataat cttgatgcca
    13741 cttagccaac aaatcgttta ccgctccgcg aacacttgaa ttgctggggt cttccacttg
    13801 gagaaagcta tcgctacttg ccaaaccagg caaatcaata ctataagtca tcggagcacg
    13861 atcgaccgca agaagagtgg gattattctc taacaaggtc tcatccacta cgagaagtgc
    13921 tccaggatag aggcgactgt cgttggtagc tgttacagaa atatcacttg tatttgtcga
    13981 caagctccgc ttctttcttt cgataacaac aaactcatcg ggtagctgat taccctcttt
    14041 gatgaaacga ttttcaatac tttctccctg atgggtcaag agtttctttt tatcgtaatt
    14101 catagctagt ataaagtcat ttactgcttt atttgccatc ttctacctcc taataagttc
    14161 ctggattgag ttgcataaac tcagacttgt tcagcgaaat cagccgtggt tggactaagt
    14221 aatccaaaat ttcctcgtac aattcttctg agacattgcg tcgccgtctg gctagataag
    14281 aagtcggaat gcccgtatta tccaacataa ataccttatc taagtcaatc aaggttggtc
    14341 ttgtaaaagg attacgagct agatccggct cttctatcat aaagttcttg accaaacgtc
    14401 tggtcaagag agctggtttg aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc
    14461 tgttgtcaat acagatatac atatgattct tcacagccaa atcgctacta atagtcggaa
    14521 aaggcaaata aagagctaca acatctcctc tcttaatcaa gcaagagcac ccccttttct
    14581 cctaatgtaa catagacagg attgaccaag tcttctgatt gactcagaat ttccaaagtt
    14641 tgagtttggc gcgctgtcaa tttagtagca tcttgtctct tcaatacaaa atgcttgtcg
    14701 ccaataacct tgacaatata atccttctcc aaagctgact ggtaaatcca catcagatgt
    14761 tgtctgtcct gagaactcaa gagagaagga ttttcaagcc tcccgatagt ctgataaaaa
    14821 tcaaaaacag gagctaactc ctgccaatct gattggctag ttgtcaaggc tagaaaaagg
    14881 gctttgcgag ctgatacttc ttggttagcc ttgagagtta ctttcccctc caagtttttt
    14941 agaaatcggg aaactccaga aagcaaattt ttctctaact gcgagaaata aaaacctttc
    15001 gttcccagac ataagtcttt catgtcgctt tctctagcaa ataagagctc aaacatttga
    15061 tagtaaaaga aaaatatctg gcactgggtc gcgctcatct tttccttatc ggcttctttt
    15121 tttaaccaga gcaagggcga caggtagctg gattgagaca tttcctctac ctcctactct
    15181 tttttaactg gagcatctgc actagctgcc acttcttttg actggatact ttcccactgg
    15241 ttaatctcct ctgagataag accttcgcat gtcttgacaa atagggcaaa agccttggtc
    15301 tttcctgcat atttctccgt ttggcattga tagaggaatt tttctttctc caggagttgc
    15361 gcagtttttt ggtaagaaat ccaattttcc tttgcattat acaaattgat aatcccctca
    15421 cacagcaagc cgagactgga taaggcaacc gaaatcaaac ggtagcgatc acctggcata
    15481 ggaatagcac aaaagacagc tatgaggaaa cctgccacga tttctgttat ttttaatacc
    15541 ttatagcgtc tacgatgttg aacgcttttc tttaaaaaat gagctatctg tacgtctaat
    15601 cgctctgtca ggtacatttc ttctggcgtc atattcgtaa ctcctttcat ttactttgat
    15661 aaccatagta taacatattt gaatatcaaa gtatagtaaa aactggacta taacttatta
    15721 gacttcctgc gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa
    15781 ctaactgatg cacgatttaa gcgtcttgtt agtgttcagc gtaccacttt tgaagagatg
    15841 ttagctgtat taaaaacagc ttatcaaaaa agtcggacaa gctggtaaaa tcttggctga
    15901 cagtggttat caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag
    15961 caaactcaag ccgctaatag ctgaagataa agcctataac catgcgctat ctaaggagag
    16021 aagcaaggtt gagaacatct ttgccaaagt agaaatgttt aaaatgtttt caacaaccta
    16081 tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggta ttatcaatca
    16141 tgaactagga ttttggtttc gcaggaagtc tattatatat gcacagacat atgaaatctt
    16201 tttgagacag cagttatgat atatttatcc attcacaaca tcttctgtac taatactaca
    16261 atattggtac attttgatta cacaatcgtt tcaaaaaata tgatggaagc ctgagtattt
    16321 tatagtaatt cccttcctat caactagatc aaccagttga gtgttgaatg ttgaaacacc
    16381 ctagcctcag caaaggacta tgatcagcat ttcctagcca ataggacgct ccaaatcacc
    16441 tattctaagt ccatcactag cttggtcagt aagatacaga ctgcaaggcg agactgacgt
    16501 ggttgatgag attttggaag agtattacaa tcatagattc accagtagac ttgaccgcag
    16561 atttaactat agtagattga aactagaata gtacatctct gcttctaaaa cattgttaga
    16621 aatcgatttg actgtcctga tcaatttgtc ctgttctcgt ttcatttcac tatactaaaa
    16681 aaccacctga aacaaatcaa gtgactagag gataaaaaca aagactaggc aaaaagtttt
    16741 gaaaagcaaa aaacgcataa tatcaggtct tgaaaaacct tgatactata cgtttgattg
    16801 tgggaagatt gacttcattt tctcctgaaa ttgaagtttt ttctagtttc cagatataga
    16861 cgaattcaat atagccatct cgctacaatt attttaacca tcgagaaaat ttttcagaat
    16921 ttcaaaaatt tcattttgat ccaatgaaat gtcatcattt tgaagaatag ttgacttcac
    16981 aggctctaat tctatcacaa agcggtgtat gtctgctttt accgcactac ttgatgttat
    17041 agccgataac ttttcatctc ctagcaagga agctgtcaaa cgggtaatgt cattcaaatg
    17101 ctttttaatg gacttactta aaccttgagc acctgtagca gagcgttccc tcatatccag
    17161 ccaagcttta gccttaaaaa taattaatac tcaatgaaaa tcaaagagca aactaggaag
    17221 ctagctgcag gctgctcaaa acactgtttt gaggttgtag atggaagctg acgtggtttg
    17281 aagagatttt cgaagagtat aaaccacaat tactcaatac cgaatacccc tgaatggttt
    17341 ctttttcatg caccaatata ttataataat cttcatccaa taataaggct gataaactag
    17401 catcttggtc aaaatgtaag ggaatttctc gaccgtcctt ctttaatgga tattctggta
    17461 agatactaaa tagttcaatc atagaaggaa actcaggatt agttgttgta aatcgaaaaa
    17521 gctgcgcttt ctcatctttc tgacttcctt gatactctcc caattctaaa aaatgattca
    17581 aggtagtata aaattcctta ttttttactt cataaatgat gaccatatca taatcttttg
    17641 ttgtgcgact tttaaatcct tgcgaatcca atacgataga ggtagcagtt cccccaatca
    17701 gaacataata gttctgaaaa tccgcaaaca tttcttgaaa aataactttc gtattagctg
    17761 gcatcatctt ctcccagata ctgtaatatc atattttcta gtgcttcact ctcttcctct
    17821 atacgtgggt catcatcatc ttttaaggtc aaataaagag aaatcggatc tacaaattgt
    17881 ttatcatgat tatttttaaa atcattccaa aactcagata caaaaggacg atatttccat
    17941 atctctagca tctttcattt taaaacatgc tgagaaagtg gcaaggataa ctgattgaat
    18001 tttctctgcc atatgacata gctagtattt tcatccgttt cagctaaaaa agttgaatgc
    18061 gacaaagcat aagcaccacc atatagaagg ttagaaacag attttatctg ctttatatcg
    18121 ccatctggca ataaaaaggc aatccacgtt aattgttcgc taggtgttaa ttccttaggg
    18181 atttcagtat cattcgcatt gagtactagt cccaatggag ggaagaagag gtttccctta
    18241 aagtctacaa acggaactct agcttgaagt aattgctttt tttcactgtc tgataacttc
    18301 gaaaacacca aaacaacatc catattggct ttttcaccca tagtgcgagc ctgagtaaca
    18361 aatgaactca aactccccct tctcttttct ttaatcaata aaaatgattc cttatgaaaa
    18421 gtcatttgag tatactcaaa cctttttaca aaactgattg gtaaagtcaa agtcagttcc
    18481 tcaatactga catcaacata aaaggattga aaaattgaca ttatcttttt gacattcatg
    18541 ttttttcctt attctatcat ttttattata ttttatcatt cggtataata aaatataagt
    18601 tttttgataa aataaccaaa aactactcgc tatcccctct cacattaccc tacatatcgt
    18661 ttgacatgcg actgatagtt caggaaaact tcaaggagaa cttttctctc atccactatg
    18721 caggacttac tatttcactt ctactcctat aggctcaatt tgacactttt ctttttcgaa
    18781 ttgctcatat gcctcctgaa tagtgagttc gatttatcca aatttatttt tgtctatttt
    18841 ggtgaatact tccacgaaga tagtctgaaa atgaatttgc accaattttc cttctctttt
    18901 taagcatatt attccagata tgattgccct cttgttcagt aataaattac gctttaaacg
    18961 cttcaatcag tatatctcct gttgtcatat gttctaaaga aaattcttct acatatggtt
    19021 taacatctct taggttatta cttcctaata tcccattatg ctttttcgct aagaaaatag
    19081 aagtcgcttc tcccttacca ataatcttgt tactatcata atttcttgtt aaatctctat
    19141 ataatgcgta ttcttcagtt ccaatgtcta tgctcacaat ctcagctgaa cccttagtta
    19201 ccaactggtc tatcctagat tttaaatggg gaattgtagg tatattgatt tcatcataca
    19261 cctcttgtgg aataacaatt ttacccgaat agagcttttc taaaagatgt tcagtgccaa
    19321 cccataaaaa tgctgaaata caatctgcat caataaatac acgactagtc aaacgacaac
    19381 tccccctctt catctagccc atatacaata tcatatctga aagcatctag taacagttcc
    19441 tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttaa attaatatat
    19501 tatcctaata ccgtttcctt tttactttct gacaaaggac gatataaact tgtatcatag
    19561 cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc ttctgcatca
    19621 aggtatccat cattcctcaa tctatataac atagctttat gactgatacc ataaaactga
    19681 cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc tctaatttcc
    19741 tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaaa ctgatccgct
    19801 tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact cttcttcacc
    19861 tcatcataat aaagatgata cagttcatgt gctaaagaaa atctttacct tcctaatgac
    19921 atgtctgaat tgactgcaat gagactgaac tgagttcctt tataacagac tctgctaata
    19981 ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac caatttaaaa
    20041 atatctatcg gcgattcacc atcagctccc aacttttttc taagatttgg agctttatta
    20101 cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca tgctttgatt
    20161 caaagacaaa tactcagcaa tcttatcttg agtaagattt gaagatattc taagttcttt
    20221 tattcttttt ccaacatcac atacatttat cacatacatt tatcacatac atttatcata
    20281 ttcatacacc tctcataaaa agaatagcac actcttgtca taatttttta aataaaaaaa
    20341 ttatgacaaa acaaggaagc aatttattga tgctgcttaa aaatctaaaa ttgatgagtt
    20401 cctatcaaaa atcgtatctt caacctcaaa acagtactta aagctatccg actcggttta
    20461 cattgtcaaa tttagatttt atttgagcat aactttctag tttgctttct gatttttgtt
    20521 taatatagta gcaaacattg aaggaaatat ctccacaaaa aaacgcatac tattaagctt
    20581 tttcaagacc taataatatg cgctgttctg atttgaaaga cattccatta ttattttact
    20641 gtaatcaagc catctggctc tactgtgaat tctggcttgt ctgccagtgt tccgtctggt
    20701 ttgaggtagt accagcctgt tccgtccgct gactggataa aggcatttga taccatggcg
    20761 ccttctttag cgtctaagta gtaccaagtg tccttgtact tgacccagcc tgtcttcatg
    20821 gcaccttctt cgttgaaata gtaccactta tcagcgattt tcttccagcc tgtagccatt
    20881 tcgcctgagt tgtcgaacca gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca
    20941 agcatatagc ctgaactgtc aaagtagtac caagtgccat tgattttctc aaacttgtct
    21001 tttggataag agccgtctga atgtacgtac cagtagccag tgtcattctt ctgccagcct
    21061 gtttcaatcg tcaagccgtt ctcaatatca tgcttaaact gctcacggct aatgccccat
    21121 ttagcaagat atggataagg gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg
    21181 caatactcgt gcgttttaat tccagctaaa ctccctgtat caagcgtttt cggcaaacct
    21241 gcttcatctg ctagattgcg taagagttcg atataaaggc ggtagtccgt catgaactct
    21301 tctttggttg aatggctttc aataagttca accgctgcat aggtctcagc attccaaccg
    21361 cccccaacgt cccaggcacc attatcaaca ggtcctacct gcatgatgca accgttccca
    21421 acaatgtgcg agaaaaaacc taattctggg tctttccgcc agtgataatc cgcttcattc
    21481 tgtacggttg aatgcggatt cccagttgag tgtgcgtgta cttgcctata tggttgcacg
    21541 ccgacttgag gcaaatctgt tcttaattta ctcacattaa tttccatatt ctactcctta
    21601 tcaattaaaa caactcattt tttacaatcc agaaccagaa actcctttat ttctacctta
    21661 caaagaagac aatcttagtc acgattaggc ttgtagatag aacctcaaaa cgcactattt
    21721 tgacactgta aataggactg acaaggtctg cattctatct acaataacac cccagactaa
    21781 aaagcttttc aaaagtatat ttt
//
LOCUS       DAVLTG010000035        20758 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLTG010000035 DAVLTG010000000
VERSION     DAVLTG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.036"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            112..3213
                     /locus_tag="VYN12_001408"
     CDS             112..3213
                     /locus_tag="VYN12_001408"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1415782.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPFYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3296..4303
                     /gene="pfkA"
                     /locus_tag="VYN12_001409"
     CDS             3296..4303
                     /gene="pfkA"
                     /locus_tag="VYN12_001409"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1415783.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4362..5867
                     /gene="pyk"
                     /locus_tag="VYN12_001410"
     CDS             4362..5867
                     /gene="pyk"
                     /locus_tag="VYN12_001410"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1415784.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDEVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6601..6826)
                     /locus_tag="VYN12_001411"
                     /pseudo
     CDS             complement(6601..6826)
                     /locus_tag="VYN12_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7674..8546
                     /locus_tag="VYN12_001412"
     CDS             7674..8546
                     /locus_tag="VYN12_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1415785.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8692..9036)
                     /locus_tag="VYN12_001413"
                     /pseudo
     CDS             complement(8692..9036)
                     /locus_tag="VYN12_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9179..9490
                     /locus_tag="VYN12_001414"
     CDS             9179..9490
                     /locus_tag="VYN12_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415786.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9494..10210
                     /locus_tag="VYN12_001415"
     CDS             9494..10210
                     /locus_tag="VYN12_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1415787.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10340..11155)
                     /locus_tag="VYN12_001416"
     CDS             complement(10340..11155)
                     /locus_tag="VYN12_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1415788.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11152..12057)
                     /locus_tag="VYN12_001417"
     CDS             complement(11152..12057)
                     /locus_tag="VYN12_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1415789.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(12328..12411)
                     /locus_tag="VYN12_001418"
                     /pseudo
     CDS             complement(12328..12411)
                     /locus_tag="VYN12_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            12455..14584
                     /locus_tag="VYN12_001419"
     CDS             12455..14584
                     /locus_tag="VYN12_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1415790.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14571..15020
                     /locus_tag="VYN12_001420"
     CDS             14571..15020
                     /locus_tag="VYN12_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1415791.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            15078..15350
                     /locus_tag="VYN12_001421"
     CDS             15078..15350
                     /locus_tag="VYN12_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1415792.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15704..15895)
                     /locus_tag="VYN12_001422"
     CDS             complement(15704..15895)
                     /locus_tag="VYN12_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415793.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16323..17081
                     /locus_tag="VYN12_001423"
     CDS             16323..17081
                     /locus_tag="VYN12_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415794.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPTRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSATLLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQLFQEISDTLTVMASEVN"
     gene            17083..19071
                     /locus_tag="VYN12_001424"
     CDS             17083..19071
                     /locus_tag="VYN12_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415795.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19113..19757)
                     /locus_tag="VYN12_001425"
     CDS             complement(19113..19757)
                     /locus_tag="VYN12_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1415796.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASTTTNIWIIFLSGFAAILAG
                     AFSMAGREYVSVSTPKDTEEAAVLREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     ANKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTRGVTFLLEQLFSI"
     gene            complement(19783..>20758)
                     /locus_tag="VYN12_001426"
     CDS             complement(19783..>20758)
                     /locus_tag="VYN12_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1415797.1"
                     /translation="KAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTIHTEIKRG
                     TVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQKFSPEMM
                     VIAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQSIEQRPE
                     AINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLIL
                     KQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIHRWLPKGTK
                     KMTPKEVAFIEKWINNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRN"
BASE COUNT         6313 a         3798 c         4386 g         6261 t
ORIGIN      
        1 atacaaatga atagaaaata aattagtaag ctgatgaaat ttttctcaag agaagccatt
       61 tataggtgaa aatggtataa tatagtgaga aggatagagg agaagtgtaa attgatcgca
      121 caactagata caaaaacagt ctatagtttt atggaaagcg tcatttcgat cgaaaagtat
      181 gtgagagcag ctaaagaata cggctacact catttggcta tgatggatat tgacaatctt
      241 tatggcgctt tcgactttct agagattaca aaaaaatacg gcattcatcc tttgctaggg
      301 cttgaaatga cagtgtttgt agatgatcag ggagtgaatt tgcgcttttt agctctatct
      361 agtgtgggct atcagcagtt gatgaagctt tcgacagcca agatgcaggg ggagaaaact
      421 tggtcagtcc tgtcccagta cctggaggat atcgcggtca ttgtgcctta ttttgataga
      481 gttgagtcgt tagaactagg ctgtgattac tatatagggg tttatccaga aacactagca
      541 agcgaatttc atcatcctat cttacctttt tatcgggtca acgcttttga aagcagggat
      601 agagaagttc ttcaagtttt aacagcgatt aaagaaaatc taccgctcag agaagttccc
      661 ttgcgttcga gacaagatgt ctttatatca gcaagttctt tagagaaact attccaagag
      721 tgttttccgc aagctttgga caatttagaa aagcttattt caggcatttc ttacgacttg
      781 gatactagtc tgaaactgcc tcgttttaat ccagctagac cagcagtaga ggagttgaga
      841 gagcgtgctg aactggggct tgttcagaag gggttgacta gtaaagaata tcaagataga
      901 ctagaccaag aattgtctgt tattcatgat atgggctttg atgattattt cttggttgtt
      961 tgggatttgt tgcgttttgg acgatcgaat ggctattata tgggaatggg aaggggttct
     1021 gcagtaggca gtttggtttc ttatgcctta gacatcacgg ggattgaccc agtagagaaa
     1081 aatctgattt ttgaacgctt tcttaatcgt gaacgctata ccatgcctga tattgatatt
     1141 gatatcccag atatttatcg tccagatttt atcagatatg ttggtaataa atatggtagt
     1201 aaacatgcgg cacaaatcgt tactttttca acctttggag ccaagcaagc tcttcgagat
     1261 gtcttgaaac gctttggtgt gccagagtat gaattatctg caattactaa gaaaatcagt
     1321 tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc agtttcgtca gcaaatcaat
     1381 agtaagttag aataccaaaa agcttttgag attgcttgca agatagaggg ctatccaaga
     1441 caaacctctg tccatgcggc tggtgttgta attagtgacc aagatttaac caactatatt
     1501 cctctaaagt atggtgatga aattccactg actcagtatg atgctcatgg agttgaggct
     1561 agcggacttt tgaagatgga ctttctggga ctacgaaatt tgacctttgt ccagaagatg
     1621 caagagttgc ttgctgaaat agaaggtatt caccttaaaa ttgaagaaat agatttggaa
     1681 gacaaagaaa cgttagcttt atttgcctct ggaaatacaa aaggtatctt tcaatttgag
     1741 caaccaggtg ccattcgtct gcttaagcgt gtgcaaccag tctgttttga agatgtcgtc
     1801 gcgactactt ctctaaatcg accgggtgct agtgactata tcaataattt tgtggcaaga
     1861 aagcatgggc aggaagaagt gactgttctg gatccagtac tggaggatat tttggctcca
     1921 acctacggca taatgctcta tcaggagcag gttatgcagg ttgcccagcg atttgccgga
     1981 tttagtcttg ggaaagccga tattttgcgt cgggctatgg ggaaaaagga tgcctctgcc
     2041 atgcatgaga tgagggcttc ctttattcaa ggttcattag aagctggtca tactgtggaa
     2101 aaagcagagc aggtctttga tgttatggag aagtttgcag gttatggttt taacaggtca
     2161 cacgcctatg cctactcagc cttggccttc cagttggctt attttaaaac acattatcca
     2221 gccatttttt atcaggtcat gttaaattct tccaacagtg attacttaat agatgcactt
     2281 gaagcaggtt ttgaagtagc ctctctatcc atcaacacca ttccctatca cgataaaatt
     2341 gccaacaagg ccatctatct aggtttgaaa tccattaaag gagtcagtaa tgatttagct
     2401 ctctggatta ttgaaaatag accttattct aacattgaag attttatagc taaattacct
     2461 gagaattatc tgaaacttcc tctgctagaa cctttggtaa aagttggtct tttcgattca
     2521 tttgaaaaaa atcgtcaaaa agtatttaat aatttagcta atctatttga atttgtgaaa
     2581 gagttgggaa gtttgtttgg agatgctatt tatagttggc aggaatcgga agattggacg
     2641 gaacaagaaa aattttatat ggaacaagag cttttaggga taggtgtcag caaacatcca
     2701 ctacaagcta ttgcaagtaa ggctatttac ccgattaccc caatcggaaa tttgtcagaa
     2761 aatagctatg ctattatctt ggttgaagtt cagaaaataa aagtgattcg taccaaaaag
     2821 ggtgaaaata tggccttctt acaggcagat gatagtaaga aaaaattgga tgtcactctc
     2881 ttttcagact tatatcgtca ggttggacag gaaataaaag agggagcctt ctactatgta
     2941 aaaggaaaaa tacaatcacg tgatggccgt ctgcaaatga ttgcacaaga aataagagaa
     3001 gcagttgctg aacgcttttg gatacaggtg aaaaatcatg aatcggatca agaaatttca
     3061 cgcattttag aacaatttaa aggcccaatc ccagtcatca tccggtatga agaggaacag
     3121 aaaaccatcg tttctcccca tcattttgta gctaaatcca atgaattaga ggagaaattg
     3181 aatgaaatcg ttatgaaaac gatttatcgc taaaaatacg gaaaatagaa gaattttaaa
     3241 atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa ggagcataaa ccaatatgaa
     3301 acgtattgct gttttgacta gtggcggaga cgcacctggt atgaacgctg ccatccgtgc
     3361 agttgttcgt caagcaattt cagaaggaat ggaagtgttt ggtatctatg acggatatgc
     3421 tggtatggtt gccggtgaaa ttcatcccct agatgcagct tcagtagggg acatcatttc
     3481 tcgtggtggt acttttcttc actcagctcg ttatccagag ttcgctcaac ttgaagggca
     3541 acttaaaggg attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg ttatcggtgg
     3601 tgacggatct taccacggcg ctatgcgttt gactgaacat ggcttcccag ctattggtct
     3661 tccaggtaca atcgataacg atatcgttgg tactgacttt acaatcggtt ttgacacagc
     3721 ggttactact gccatggacg ctatcgataa gattcgtgat acatcatcaa gtcaccgtcg
     3781 tacttttgta attgaagtta tgggacgtaa cgctggtgat atcgctcttt gggctggtat
     3841 tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg aagatatcgt
     3901 agcaagcatc aaagctggtt atgaatgtgg taaaaaacac aatatcatcg tcttagctga
     3961 aggtgtgatg tcagcggctg aatttggtca aaaacttaaa gaagctggag atacaagcga
     4021 ccttcgtgta acagaacttg gacatattca acgtggtggt tctccaactg cgcgtgaccg
     4081 tgttttggcg tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag gtatcggtgg
     4141 tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg gtactgcaga
     4201 agaaggggca ttgtttagcc ttactgcaga aggtaagatt gtggttaaca acccgcacaa
     4261 agccgatatt gagctatcta gcttgaataa gagcttgtca taatttacaa tttagttaat
     4321 aagaccaaaa aggtcatata tataaaggag tcacaaaaat catgaacaaa cgtgtaaaga
     4381 tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc ggtgaggacg
     4441 gatactgggg tgaaaaactt gatgttgaag cttcagctaa aaacattgct aaattgattg
     4501 aagctggtgc taacacattc cgattcaact tctcacacgg cgaccaccaa gaacaaggtg
     4561 agcgtatggc aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt ggtttccttc
     4621 ttgatacaaa aggacctgaa atccgtacag aattgttcga aggtgaagct aaagaatatt
     4681 catacaaaac tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa tcaactcgtg
     4741 aagtgattgc gttgaacgtt gctggtgctc ttgatatcta tgatgaagtt gaagttggtc
     4801 gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa gatgatgcaa
     4861 ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa aaaggtgtga
     4921 acatccctaa cactaaaatt cctttcccag ctcttgctga acgcgataac gacgatatcc
     4981 gtttcggtct tgaacaaggt atcaacttca tcgcaatttc attcgtacgt actgcaaaag
     5041 atgtgaacga agttcgtgca atctgtgaag aaactggaaa cggacatgtt caattgttcg
     5101 ctaaaatcga aaaccaacaa ggtatcgata acttagatga aatcatcgaa gcagctgatg
     5161 gtattatgat tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg gttccagttt
     5221 atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa agttgttatc actgcaacaa
     5281 acatgcttga aacaatgact gaaaaaccac gtgcaactcg ttcagaagta tcagacgtat
     5341 tcaacgctgt tatcgacgga actgacgcta caatgttgtc aggcgagtct gcaaacggta
     5401 aatacccact cgagtcagta actacaatgg ctacaatcga caagaacgct caagctcttc
     5461 ttaatgaata cggacgtctt gattcagatt catttgagcg taactctaag acagaagtaa
     5521 tggcttctgc tgttaaagat gctactagct caatggatat caaattggtt gtaactctta
     5581 ctaagacagg tcatactgca cgtttgattt ctaaataccg tccaaatgct gacatcttag
     5641 cattgacatt tgacgaattg acagaacgtg gcttgatgtt gaactggggt gttatcccaa
     5701 tgttgacaga tgctccatct tcaactgacg atatgttcga aatcgctgaa cgtaaagcgg
     5761 tagaagcagg tctcgttgag tcaggcgatg atatcgttat cgttgctggt gtgccagtag
     5821 gagaagctgt tcgcacaaac acaatgcgta tccgcacagt acgttaagaa aaatataaaa
     5881 acctatcata tccagctttc tagcctgtat gatgggctct ttttttgtcc agggggcaaa
     5941 aagggggcaa aactttcata atggattgat actcttcgaa aatctcttca aaccacgtca
     6001 gcgtcgcctt accgtatata tgttactgac ttcgtcagtt ctatctacaa cctcaaagca
     6061 gtgctttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatga
     6121 aataagatat gcataaattg attagaaagt caaatgaatt tctacaaatg ttttagcaat
     6181 cgcaatctac ttgtctagat tcgatctgat atattttcga tttaatgata tggtatttaa
     6241 aacctccaaa gtagcttgct ccattctttt acctacgtga gtctagatgt tatttactgt
     6301 tttagcgttt ttgtgttcta ctctaaccat tatagcattc ttctcagcta gtgtactaag
     6361 gagtgtgtgc ctgaaaatat gggaactaag gggctggttt atcggtttct ctagtttagt
     6421 atttgccttt tgcaaagtga tcttaaatgc ctttctctaa atttacatat cactattgtt
     6481 taacaaaatc taatctattt taggtcactt attctttttt tgaaatgtag aatgaacttt
     6541 ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat atcgccattc tccccctttt
     6601 ttaattctcc ctatatagcc tgacaacttt tccgatggta cgaatatggt tgctttcgtc
     6661 taggtggatg tcggagtatt cgggattgag tttttttgag gtagccttgg cggagtttct
     6721 tgacatagtt agtgccgtct acttggaaga tgccgatggt attatagtca atctgtgggg
     6781 tattcttgat aaataggtag tcgctgtttc ttatctttgg ctccatggac ttgctgacga
     6841 cataagcgat tgggtcgtag tcgtctggga taatggaaac tccataacta aatcgtcgtc
     6901 ctgcatcaag cggctacctg cagagataaa ctacctaaca cgagagtaag tagtctgtct
     6961 gtagtcgtcc agtctgatga tttttacgat acttcgtttt tctgatcata cagttgcctc
     7021 tcggcatagg tcagaacttt accttgtctg ggtggtgccc gttggtcgta gatagattgg
     7081 atatcgctag gagaatcctt ttgaactgga ggaaagaggg catcaatcaa gctactgaat
     7141 actttaacta agtcaaatat agtatttttc ttagtagacc taaccctttt ttcataattt
     7201 ctaatggtgt ttttacttat acctatctta gtacccaatt cttattgagt ccaaccatta
     7261 ctagtctata ttgttttata gttgattgag tttggaatag tacgctgtag ctgctaaaac
     7321 atttctagga attaatttgc ctttcctaat agagttgttc atatcttatt tcaatctact
     7381 atatttttca cctctaacaa tcgcaatctc ttctttatcc atgaacgaaa acgctttcta
     7441 tctttgtaag taaagcatca cacgaaatcc acgaaaatga aaacctttgt tgtgttttcg
     7501 taaaaaattt gttgacagag cacgaaacgc ctactataat taaatcaagt ttaaggaaat
     7561 aacaaaaaaa caaatcggag ggaaagacga tgaacacatt aaatgagaaa gtaatcaata
     7621 tctgtaaagc agtagttaaa gaaactttaa tccaagacat ttaggagaaa gaaatgaaga
     7681 aatcaagaaa attagccaca ttaggaatct gttcagcctt gtttttaggc ttggctgctt
     7741 gtcaacaaca acatgctact tctgagggga cgaatcaaag gcaaagcagt tcagcgaaag
     7801 ttccatggaa agcttcatac accaacctaa acaaccaggt aagtacagaa gaggtcaaat
     7861 ctctcttatc agctcacttg gatccaaata gtgttgatgc attttttaat ctcgttaatg
     7921 actataatac cattgtcggc tcaactggct tatcaggaga tttcacttcc tttactcaca
     7981 ccgaatacga tgttgagaaa atcagtcatc tctggaatca aaagaagggc gatttcgttg
     8041 ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa ttcagtcacc attccaaagc
     8101 ttgaaaagaa tgaccagttg cttttcctag ataatgatgc gattgataaa ggaaaggtct
     8161 ttgattcaca agataaggaa gagtttgata ttctattttc gagagttcca actgaggcaa
     8221 ctacagatgt caaggttcac gctgaaaaga tggaaacatt cttctcacaa tttcaattca
     8281 atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa tctggatggc gagtatctgt
     8341 ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg tttcttattt gtagagaaat
     8401 tgactttcga agagccctac caagcgatta aatttgctag taaggaagat tgctacaagt
     8461 atttgggcac caagtatgcg gattatacag gcgagggact ggctaagcct tttatcatgg
     8521 ataatgataa gtgggttaaa ctttaatagt gttatgatat gacagtaatc ttaggatttt
     8581 tatttctatt tttgatgact tggtgggtta tttcaatcgt taatagccag aaaccacgca
     8641 aaaatgaaac atttattggc tatatccaaa gatacgatat tgatgggaat ggctatcaat
     8701 cattaccgtg tcctcagaat tgagaggagt tcttgaaatc gtaaaactac tttgaacaag
     8761 agttacttca acccattggc tccgacggat taagttgctt tcgtgaacac caaaatcagc
     8821 cgcaatttct tcataagtgc ggtattctcg cacatattga agagtggcca taagaaggtc
     8881 ttctaggctt aatttaggtt ttcgtccccc ttttgtgtgt ttaagttgat aagcagtttt
     8941 taatacagct aacatctctt caaaagtggt gcgctgaaca ccaacaagac atttaaatcg
     9001 tgcatcagtt agttgcttac ttgcttcata attcatagaa ctactatacc atattttgtt
     9061 tcgcaggaag tctaatgcta aaatcttatc agtgagaaga tttcttaaag tttattcttt
     9121 gtagtttcat ctgtattagt atataattta acttagagaa aataggagga ctaatcgaat
     9181 ggaattaaaa gattttacag aaaaagaaca ggaaatgatt aagaaaaggc ttacaatgtc
     9241 taatattagt gacaaagaaa ctactgagaa gattctggcg ctagtaccac aagacttgat
     9301 taagcgaatc ccgttttttg tcagaaaaca tgctacaaca cgtacgatta aacgcatttc
     9361 aattgaatac cctgaactct acgctgtagc tcaaacaagt ggtgagattc cagaaaaaga
     9421 acgcgaagaa ttgcgtcaga ttatcacgac tatctttgaa caaaagatga ataagcatag
     9481 tattaagtag agaatgaaaa aatattttat tagcggtttg ggaagcaatg cctatcatag
     9541 caaggatttt tttcaagaac tagattcgca ggtctatttt ctaaatccat atgaaaagca
     9601 tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat gagattgtag aggaagaatc
     9661 tatctgtctg ataggccatt ctcttggagg agatttagct cgttatttcg catcggaatt
     9721 tgaagaagta aagaaactga ttcttttgga tggtggctat ctagatttag ataagatttt
     9781 acctttggat acagagttag aggaaactaa aaattatatc aaatctcaaa ttgtttcgga
     9841 cttagctctt cttatttcta aagagaagtc cgaagcaaag cattggtcag aaaatatgga
     9901 gaaagctgta agacagtcct atcactggaa tgttgagtat aatagatatg agttggctat
     9961 aaattatgaa aatatagaag cgatactccg cctacggaga aaaatacaag cttttaagag
    10021 agaagtggga gataccttgt ttattagtcc tcgctatcct aatggagcta catggagaga
    10081 ggaagcccta aaagaattgc cagactattt taatactatt tttttagaaa actttggcca
    10141 tgagctttat actcaagcac ctaaagaaat cgctagtcta atgaatgagt ggctcgctta
    10201 ttttctatga gctacttgta ttgctggaaa tggtataaga tgaaaatcta caagtcacta
    10261 attttcatat aacaaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt
    10321 cgtttttatc ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga
    10381 ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt
    10441 gattgaccag ttttcctttg gctgtaatcc aggtgttgtt ttcatactgc cgggtattgc
    10501 ccttggtcag caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga
    10561 acagaaattg actattggca tgactggggt cgttatagac aaagcctgta aactggattg
    10621 tcttgccctc aaattcatct ggatagtcgt agatagcctc catgacttcc atatagtttt
    10681 cattagtgat ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct
    10741 tttcataggc tgattttgaa aaataagaac tagtatctgg tttcaaatat tggcttgtcg
    10801 tcccttcact tgtctgaata gctagatccg ttccttccga tagggggaaa tgataacctt
    10861 tagcagaaac ggtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg
    10921 gaatagccag aagagaaata ctcgtcatct tggccaatcg gctgttcaga tgactgtggg
    10981 ttttgacttg cttcatccag atatacaatt gaacaattgc caagataaag gaaagcacca
    11041 tggagatata ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca
    11101 gatggaggta aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat
    11161 gactccaatc aagagagaat aggctaaaac gaccagagtc acaatcgtaa tgaagtgact
    11221 aataaatcgt gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg
    11281 gccaatgacg agaaaggcca gaactggtgc caaaccgaaa ctcgagagaa gagaagcacc
    11341 tataaaggca tccgcctcac tacagagcga aagaagaaag gccaaaatca tcaagagcag
    11401 gatggcaaaa agaggagtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg
    11461 tattatagaa gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc
    11521 aatggcctgc acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg
    11581 ctcatgacaa gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa
    11641 aattcctagt attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa
    11701 ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt
    11761 cacaagaaaa ggaacggctg tgtaactggg aacctttttt tccagaaaac gattgatgat
    11821 ggggacgatt ccacattcac aagaagggaa aagcataccg acaaaggtcc caaaaaagat
    11881 tctcccccaa cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc
    11941 aatcagccct gagacaatgc ttcctattag aacgaaggga agggcttcaa tgataatgga
    12001 gagaaaaatg gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta
    12061 gtttttcttt tctgctttgg cttttttctc tttgtcatca gggaaagtaa cttgtttcaa
    12121 atcagggagt ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt
    12181 tacagccata ggtgtacctc gattctaaag tctacctcta ttatactatt attttgcgga
    12241 aaagggagtt ttttaatttg ttttcgatag ttgatacact tcgaaaatct cttcaaacca
    12301 cgtcagcttc gccttaccgt atatatgtga cttatccaca acctcaaaac agtattttga
    12361 gcagcctgcg gctagcttcc tagtttgctt tttgattttc attgagtatg aaaaggattg
    12421 gagaaagcct tccagcttgt ggtataatag atttatggat aaaaaatatg aaaaaatctc
    12481 tcaggatttg ggagtgatgt taaagcaaat tgataccgtt ctaagtttga cagctgaagg
    12541 ggcgactatt ccctttatcg cgcgttatcg caaggacatg actggtagtc tggatgaggt
    12601 ggcgattaag gctattattg atttggataa aagtctgaca aatctcaatg accgtaagga
    12661 agctgtctta gctaagattc aagaacaagg taagttgacc aaggaattgg aagaagctat
    12721 cttagttgcc gaaaaattag cagacgttga agaactctat cttccttata aggaaaagcg
    12781 tcgtaccaag gcaaccattg cccgtgaagc tggactcttt cctcttgctc gtttgatttt
    12841 gcagaatata gttgacttag agaaagaagc tgaaaagttc gtctgtgaag gatttgcgac
    12901 tggcaaggaa gccttgaccg gtgcagttga tattttggtc gaagccttat cggaagatgt
    12961 gaccttgcgt tctatgactt atcaggaagt gctgagacac tctaaactta cttctcaagc
    13021 caaggatgaa agtcttgatg aaaagcaggt ttttcagatt tattatgatt tttcagagac
    13081 agttggaact atgcaaggct atcgtacctt ggctctcaat cgtggggaga aacttggtgt
    13141 cttgaagatc ggttttgaac atgcgacgga ccgtattctt gccttctttg ctactcgttt
    13201 caaggtgaaa aatgcttata ttgatgaagt tgttcagcaa tccgttaaga aaaaggtctt
    13261 gcctgctatt gagcgtcgta ttcggacaga attaactgag aaagctgaag agggagctat
    13321 ccaacttttt tctgacaatc tgcgcaatct cctcttggtt gctccattga aagggcgcgt
    13381 ggttcttggg tttgacccag cctttcgtac aggtgccaag ctagctgtcg tggatgcaac
    13441 aggaaaaatg ctgacaactc aggtcatcta tcctgttaaa ccagcatcag ctcgtcaaat
    13501 cgaagaagcc aagaaagatt tagcagattt aattggtcaa tacggtgtag agattattgc
    13561 cattggaaat ggaacggcca gtcgtgaaag tgaagctttt gtagcggaag ttctgaaaga
    13621 tttccctgaa gtcagctatg ttatcgttaa tgaaagtggt gcttctgtct attctgccag
    13681 cgaacttgct cgtcaggagt ttccagactt gaccgttgaa aaacgctctg ccatttctat
    13741 cgcccgtcgt ttgcaagatc ctcttgcgga attggtcaaa atcgatccta agtcaattgg
    13801 tgtcggtcaa taccaacacg atgtcagtca gaagaaacta tctgagagtc tggactttgt
    13861 tgtcgataca gtggttaacc aagttggtgt caatgtcaat acagctagcc cagctcttct
    13921 ttcacacgta gctggactca ataaaaccat ttctgaaaat atcgtcaaat accgtgagga
    13981 agagggaaaa atcacttcac gctcccaaat caagaaagtt cctcgtttgg gggccaaggc
    14041 ttttgaacag gctgctggtt tcctccgtat ccctgaaagt agcaatatcc ttgataatac
    14101 aggagttcac ccagaaaatt acgctgccgt taaggaactc ttcaaatgct tggacattaa
    14161 ggatctgaat gaagaggccc aaagtaaact caagtcgctt tcagtcaagg aaatggcgca
    14221 agagttagac cttggtccag aaactcttaa agatatcatt gcagatcttc tcaaaccagg
    14281 tcgagatttc cgtgattcct ttgatgctcc agttctccgt caagatgtcc tagatatcaa
    14341 ggacttagtg gttggacaaa agctagaagg agtggtgcgt aatgttgttg atttcggtgc
    14401 ttttgttgat atcggaattc atgaggacgg tctcatccat atttcccata tgagtcgcaa
    14461 gtttatcaaa caccctagtc aagtggtggc agttggagat ttggtgagcg tttgggttaa
    14521 gaaaattgat actgaacgtg aaaaagttaa tctgtctctc ctagctccaa atgaaactga
    14581 ctgattacgt caagcaggtt tcactagaag acttcggcag accttttatc catcatgtcc
    14641 agtggaatag gcgtctacgt tcgacaggtg ggcgattttt ccccaaagat gggcatttgg
    14701 attttaatcc caaggtttat caggaactgg ggttggacgt ttttaggaaa attgtccgac
    14761 atgaactctg tcattatcac ctctattttc aagggaaagg ctatcaacac aaggatcggg
    14821 attttaagga actgttgaaa gcagtggatg gattacggtt tgtaccatcc ttgcccaata
    14881 gtaactccaa gccaatcaag ctctatcgtt gccaatcctg ccagcaaact tatcagcgta
    14941 agcgtaggat tgatacccaa cgctatcgct gtggactttg tcgaggaaag ttgctattag
    15001 taaatcagcc tgaggactga tgaaagccga gcctatccgt gatatactag tctaacctag
    15061 cagaaagagg aaatatcatg aacagtaagt tttataaaat gagacgaaat cgcatgattt
    15121 caggagtttt agcaggtctg tcagacaagt ggaactttga tgttaccctt gtacgttttc
    15181 tgtttgccat ttttacagtc gcaaactttg gacttggggt gattatctat atcatcctag
    15241 cttctatcat gccaaccaag gaagaaatcg aagcagaaat gtacggaaca ggcccacgta
    15301 aacgcaaaga agctcaagcc attgacgata atgaaggctg gttttggtga ggttttacaa
    15361 aagatttgga atacgcaaaa agctttaaat caatagtcta aactgcttga tttaaagctt
    15421 ttttactttt atactcaata aaaatcaaag tgcaaactag gaagccagcc gcaggctgta
    15481 atttagtcgg caatgtgaag ttgatatagt ttgcactttg atttttgaat agtattaata
    15541 atatttcgcc agcttcatcc acaaactata gtggattgga actagaatag gacacctata
    15601 cttctaaaaa attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttatt
    15661 tcattttatt ataaaagcag taatttaaac gcagtttttt aatctatttt tgctgttgag
    15721 acaatacatt tttggaaaaa tggtggatgc tgataacaac tgataaccag caaataacat
    15781 aagcagtgcc ggtaaattct gtactgataa agtgtgtgtg ttcaactaag agctgaccga
    15841 tgaatggaga gagcagatag agaagtccga tgagtatatg ttctttgtgt ttcattaaag
    15901 cgcaccttct ttccttatag gttgaacgac ttgcaagtgt taaattgaat ggtatgttat
    15961 ctaggtaagc ttactaaaat gttagttccc gcttcctcct tttcaaagta agccttttca
    16021 cacttatatt ttacaacttt aaaaatagga aatcaaatca ttttctaagt aattttgctt
    16081 atatttcacc caatcttaca aaaatgtaag attaaagtct cttttgtaag gttaggttat
    16141 ggcaagcggt ctttttttga tgtaaactag actcataaag aacaaaggag taacatcatg
    16201 aaacaaatct tacataagaa aactagaaaa ccaagtcaca aagaaattga gcgcgttcag
    16261 ctgggatgca ctatgatgca agctacattt catttgatgg gatattaaga aaggagattc
    16321 tcatgacact tttagatgta aaacacgttc aaaaaattta taaaacacgt tttcagggca
    16381 accaagtaga agccctcaag gatattcact ttaccgtaga aaagggtgac tacgttgcca
    16441 tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa tattctagct atgttggata
    16501 aaccaactcg tgggcaggtt tacttgaatg gaactgacac cgcaactatt aaaaattcac
    16561 aggcttctag tttccggcgt gaaaagctag gatttgtctt ccaagacttt aacttgctag
    16621 atactctgtc tgttaaggac aatatcttgc ttccgcttgt cttgtcaaga agacctataa
    16681 cggagatgat gaagaaattg gtggtgacag ctgagaatct gggtattaac caattgcaag
    16741 agaagtaccc ttacgagatt tctggtggcc agaaacagcg tgtagcagta gcccgcgcca
    16801 tcatcacaga acctgaaatt ctccttgcgg acgagccaac aggagccctt gattccaagt
    16861 catctgcaac cttacttgat gtctttaatg aaatcaatga gcgtgggcaa accatcctca
    16921 tggtaaccca ctcaacagca gctgctagca gggccaagcg tgttctcttt atcaaagacg
    16981 gcattcttta caaccaaatc taccgtggag agaagacaga gcgtcagttg ttccaagaaa
    17041 tctctgatac cttgactgtc atggcaagcg aggtgaatta gtatgtttcg attaaccaat
    17101 aagttagcgg tatcgaactt gattaaaaac cgcaaactct actatccctt tgcactggct
    17161 gttctcttgg cagtcaccat cacctatctc ttttactccc taaccttcaa tcccaagatt
    17221 gcggaaatcc gtggaggaac caccattcaa gcaacacttg gatttggtat gtttgtcgtt
    17281 acccttgcgt cagccattat cgtcctctat gccaatagtt ttgtcatgaa aaaccgttcc
    17341 aaggaactgg gtatatatgg catgttaggc ttggagaagc gccatctaat cagtatgacc
    17401 tttaaggagt tagtgctatt tgggattcta actgttggag caggaatcgg tattggagcc
    17461 ttgtttgaca agttgatttt cgctttccta ctcaaactga tgaaattgaa ggtggaactg
    17521 gtcgctacct tccagatgaa agttgtcatt acagtacttc ttgtcttcgg tttgattttc
    17581 ctaggcctca tgttcctgaa tgcccttcga atcgcccgta tgaatgccct ccagctctca
    17641 cgtgagaaag ctagcggaga gaaaaaaggt cgcttccttc ctctccaaac tattcttggt
    17701 tccataagtt tagggattgg atattatctt gcccttacgg taaaagatcc tcttacagcc
    17761 ttaacaacct tcttcatagc tgttttactg gttatctttg ggacttatct tttgttcaat
    17821 gcagggatta ccgttttcct tcaaatctta aagaaaaata agaaatacta ttaccaacct
    17881 aataatctca tatctgtttc taacttgatt ttccgtatga agaaaaatgc agttggacta
    17941 gcaactatcg ctattttgtc aacaatggtt ttggtaacca tgtcagcagc gacaagcatt
    18001 ttcaattccg cagaatcctt taaaaaagtt ctaaatcctc atgattttgg ggtttcaggg
    18061 caaaatgttg aaaaagaaga tttggacaaa ctcttgagcc agtttgcaag tgacaaaggt
    18121 tataagatta aagagaaaga agtgcttcgt tacagtaact ttggtattgc aaatcaagaa
    18181 ggaaccaagt taactatttt tgaaaaagga caaaaccgtg tccaaccaaa aacagttttc
    18241 atggtatttg accaaaaaga ttatgaaaat atgactggtc aaaaactgtc tctatcagga
    18301 aatgaggtcg gtctctttgc caaaaatgac ggactgaaag gacagaaagc tctaactcta
    18361 aatgatcatc aattttctgt caaagaagaa tttaataaag atttcattgt caaccatgtt
    18421 ccaaataagt ttaatatctt gactactgat tacaattacc ttgttgttcc tgatttacaa
    18481 gcctttttgg atcaattccc agattcggct atctataatc agttttacgg tggtatgaat
    18541 gtagatgcca gcgaagaaga acaactcaag gtcgctgagg agtatgaaaa ctacctcaat
    18601 caatttaatg ctcaattaga cacagaaggt agctatgttt atggtagcaa tctagcagat
    18661 gctagttctc agatgagtgc cctctttggt ggtgtcttct ttatcggtat tttcctatcc
    18721 attatcttta tggtcggaac tgttctggtc atctactaca aacaaatttc tgaaggctac
    18781 gaagaccgtg aacgctttat tatcttgcag aaagtcggtt tggaccaaaa gcaaatcaag
    18841 caaaccatca acaaacaggt tttaactgtt ttcttccttc ctttgctctt tgccttcata
    18901 catctcgcct ttgcctacca tatgcttagc ctgattttaa aagtgattgg tgtactggat
    18961 acgactatga tgttgattgt gaccttgtct atctgcgcta tcttcctcat cgcctatgtg
    19021 ctgattttta tgattacttc aagaagttat cgcaagattg tgcaaatgta aaaaagatac
    19081 ctcgacttca aaatcgaggt atttcttgta ttctaaatgc tgaaaagttg ttcgagcagg
    19141 aaggtaactc ccctggtcaa gagaccaata gcaaggttcc gaatcatagc tgttctagtc
    19201 ggatcctttc caagtctggc actagtgtaa ccagtgagaa gaagggccac accgacaata
    19261 aggacagtag cagggatgcg atattcactt gggaatatgg tcactgacag cattggaggc
    19321 aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag cgtgccaagg attggtaaat
    19381 tcttcatact caatcccata tttttcctct accagagcct tgagtggatt tttaagaaag
    19441 atcttattag ccaagagttg ggcagaagtt ttgcattctc cattttggat ataagcagca
    19501 tagagggatt ttttggctag ttccctatct tggtctagca agagtttttc tcgcaaaacg
    19561 gcagcttcct cggtatcttt tggagttgaa acggatacat attctctacc agccattgaa
    19621 aaggcaccag ctaagatagc cgcaaaacct gataaaaaga taatccagat attggtcgtg
    19681 gtactggcaa ctccgataac cacaccagca atggaaataa ttccattgtt agcatcaaga
    19741 acacccgcac gcaggatatt taaacgacct gcaaaatttg aatcaatttc gtgatttgtt
    19801 tctgacgcta aatttcaagt tcaagttagc catcaagaag tcttctctgg gtgacttgta
    19861 gttcaagcat tttttaggat agttgttaat ccacttttcg atgaatgcga cttctttggg
    19921 agtcattttc ttggttccct taggtaacca tctatgaatg agcctgttgt gattctcatt
    19981 agttcccctt tcccaagagg cataggggtg cgcataatag atgtgctcct cagaaaatac
    20041 atcaaacaag cgattgaatt ccgttccatt atctgccgtg atggaaagaa tcttgtgttg
    20101 ttttaagatg agttttagag cctgattgac cacctcagca cttttatttg gaatcaatcg
    20161 gatgatctga tgtctactct ttcgatccgt caagacaagc aagcagtagt ttttcgctct
    20221 cgtaagtaga accgtatcaa tctcataatg cccattctcc aagcgaagat tgatagcttc
    20281 aggccgctgt tcgatggatt gaccagcagg tttaaagttg gtgctagcct gtttcttaag
    20341 cgcttttcct tttctagggt aaagcagatc ctgcttgctt aaccccaatt ttccacgatg
    20401 aatccaatag taaatggttg aaattcccac gttaacccct ttagcaataa ccatcatttc
    20461 aggcgaaaat ttttggttat gatagtggag aatcttttcc tttagttcct tggtcaagct
    20521 tgatttcttg accgagcgct tgcgattgtt ttcataagac tgttgagcat agtcggcaga
    20581 ataaacctct ttgaagcgcc cttttccaag acattgtcgg actgtcccac gcttgatttc
    20641 agtgtggata gtttgaggag cttttccaag tagagaggca atttctctat ttgatttccc
    20701 ttcttttttc catctttcga ttaagcgacg gctatcgatt gtcaaatgtt tggctttt
//
LOCUS       DAVLTG010000036        17942 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLTG010000036 DAVLTG010000000
VERSION     DAVLTG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17942
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.037"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(220..366)
                     /locus_tag="VYN12_001427"
     CDS             complement(220..366)
                     /locus_tag="VYN12_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415798.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(363..818)
                     /locus_tag="VYN12_001428"
     CDS             complement(363..818)
                     /locus_tag="VYN12_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415799.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(955..1839)
                     /locus_tag="VYN12_001429"
     CDS             complement(955..1839)
                     /locus_tag="VYN12_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1415800.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(1843..2229)
                     /locus_tag="VYN12_001430"
     CDS             complement(1843..2229)
                     /locus_tag="VYN12_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1415801.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2222..3565)
                     /locus_tag="VYN12_001431"
     CDS             complement(2222..3565)
                     /locus_tag="VYN12_001431"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1415802.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRFFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3647..4531)
                     /locus_tag="VYN12_001432"
     CDS             complement(3647..4531)
                     /locus_tag="VYN12_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415803.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4543..5160)
                     /gene="cysE"
                     /locus_tag="VYN12_001433"
     CDS             complement(4543..5160)
                     /gene="cysE"
                     /locus_tag="VYN12_001433"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1415804.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5176..7389)
                     /gene="pnp"
                     /locus_tag="VYN12_001434"
     CDS             complement(5176..7389)
                     /gene="pnp"
                     /locus_tag="VYN12_001434"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1415805.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDIIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            complement(8074..8940)
                     /gene="metF"
                     /locus_tag="VYN12_001435"
     CDS             complement(8074..8940)
                     /gene="metF"
                     /locus_tag="VYN12_001435"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1415806.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQYMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     NAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9004..11253)
                     /gene="metE"
                     /locus_tag="VYN12_001436"
     CDS             complement(9004..11253)
                     /gene="metE"
                     /locus_tag="VYN12_001436"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1415807.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGKNAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(11514..11780)
                     /locus_tag="VYN12_001437"
     CDS             complement(11514..11780)
                     /locus_tag="VYN12_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415808.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(11906..12353)
                     /locus_tag="VYN12_001438"
                     /pseudo
     CDS             complement(11906..12353)
                     /locus_tag="VYN12_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12509..13510
                     /locus_tag="VYN12_001439"
     CDS             12509..13510
                     /locus_tag="VYN12_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1415809.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            complement(13578..15980)
                     /locus_tag="VYN12_001440"
     CDS             complement(13578..15980)
                     /locus_tag="VYN12_001440"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1415810.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAEDALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(16057..16566)
                     /locus_tag="VYN12_001441"
     CDS             complement(16057..16566)
                     /locus_tag="VYN12_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415811.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(16566..17612)
                     /gene="pheS"
                     /locus_tag="VYN12_001442"
     CDS             complement(16566..17612)
                     /gene="pheS"
                     /locus_tag="VYN12_001442"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1415812.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT         5019 a         4060 c         3477 g         5386 t
ORIGIN      
        1 ttccattgct tccagataat cactcgtagg cgagtacgca agcgctcatc tatgctagtg
       61 actatacttt tcatatttat aattcattcc tttcgtttca ctcaaggcac aacacagaat
      121 gaaaaagtgt tgtgatcttt attttgtttt ataataatag tgagaaagcc tatcactact
      181 acaaatcacg gggaggtgaa taagtgagtg gtacagccac tacctcgcat attttgtcac
      241 atcatttaac ggtacataat aagttgtacc atctgaataa gttgctacaa tatcatttgc
      301 atgctctcct tcacctttag caaaggttgg agctcctgct ggatgatttt tatttgcctc
      361 tttcaatttt tcaataatgg cattttttct gtatctttta tattatcagg atttttcact
      421 aagattttgt ctggatatgt cggtttagca gaaacaattt ttactgttac ttctttttta
      481 ttcgaagcac ttgtccagtt tccagcatta tctttagcat ttaattttac agtaattcct
      541 gaactaggaa cttcagtagc aggttgatta tcaacattat tcaactttaa tttcaaaaga
      601 gctgttgcat cagacgtttt atcaatcgtt atatataatg atgaattgtt attataaaca
      661 gttccttcat atttagctgt ttgtgagcta cttgaaacag aactgaaatt atacccacta
      721 cctccctgat tatcttcaat gcttacgtct aaatgaactt ccccactatt atttggctta
      781 gcaacaactg ttatagtaaa ataacataaa atttgcataa atagattagg gaaatcaaag
      841 cagcttctag gaatgtttta gcagtcacag tgtactttcc cagcatcaag ccactataac
      901 tctgcacata aaaatggaga agatggcaat cctcttctcc aaatattaac ttctttacaa
      961 accaactata gttgacaaag aacctaaaat caattgataa cacaaggtca ggtcggtcaa
     1021 ctctttcaac tgaagccctg tcaactcttc ccatttatca atcttgtatt ggagagaatt
     1081 gcggtgcaga tagagttgct gggctgtttt agtgagaaca gcactatttt cccaaagaga
     1141 gagaatgatt tcctgaatct gatcttgatc caaaatcatc tggtgtagac attccttgat
     1201 tggcttcaag tccacgagtc tttctcccat actccaaaga tagagctgag aaaaagtatg
     1261 aacaccttgg tgaccctgac gccaccatgt cttgaacaaa tcccgctcag ctttgattaa
     1321 gtctgatagg gcttgatgtc ccgtctgaga ccaaacctga cccaacatga tagaaagacg
     1381 aagtccaaag tcatactcaa ccgcttcaat cgtatcactt aaaatatctc ttacagaagt
     1441 gtatttgtct tgttgaagca cgaaaacata atcctgagct ccgacctgta gcactgtctg
     1501 acaattcgga aaaagagtcc gcatcatatc tagccaagaa gccagatttt cctgctgaaa
     1561 ataagaaaga tggcaataaa ccaactgaat ctttttaaaa acttgcggtg cctgtccctt
     1621 gccctcaacc agataggaat accaagggtt tagcgaacga gcctgctcct gctgggtcaa
     1681 aagggcaacc aactgctttt cacgctcgct gagcccagct tcctccagca aaatccactg
     1741 ctgagaagct aaagggagcg tgagatagcc ctctttctct actggttggt ctgaaatccg
     1801 agcctcagga aaccagtctt gtagttcttt tgccctcatg ttctagccct ccactttttg
     1861 gatgcaccat gaaaccaaac tctcaagacg ttccagattc tcagtcatat ggagatagcc
     1921 cataaccgct tcaaatcccg tggacatacg ataagtcacg acatctgcat ttttagcctt
     1981 tgtgtggcta ttggtattgc ggccacgttt gtagatttct tcttcttttt ccgttaggac
     2041 ctgctcctcc aacatgagag caatcaggcg agcctgagcc ttggctgaca cgtacttagt
     2101 tgcttcttga tggagtttat tgggtttggt catacctttg aggatgaggt gacggcgaat
     2161 atacatagaa tacaccgcat ccccctcaaa ggctagcgca atcccgttaa tgagattgac
     2221 atcaatcacg tgtccacctc actccatcct tggtatcaag gagcttaatt ccttgagtaa
     2281 ccaattggtc acggatttgg tctgctgtcg caaagtcacg attggcacgc gcctcttggc
     2341 gtttttgaat caagtcttca atctctgcat ccaaaacttc ctcaacaaag acaattccaa
     2401 aaatttctaa catatctgca agagcttgct tgacacttgc atcatagttc cctgagttga
     2461 tccatttggc catttcaaag acaactgtga taccgttggc agcattaaaa tcttcatcca
     2521 tagctgctac aaacttatct ttaaagtttt gtaactcttg ggcatccaca tttcctgtaa
     2581 atggttgttc gtaagtattc ttgagatact tgagattggt ctcggcatcg cgaactgcct
     2641 tttccgtgaa gttgataggc ttacggtagt gctgggtcgc aaagaagaaa cgaagtactt
     2701 gcccatcaag agttttaagg gcatcgtgta ccgtaatgaa gttacccaag gacttagaca
     2761 ttttgacatt gtcgatattg acaaagccat tgtgcatcca gtagttagca aaagccttgc
     2821 ctgttttagc ttcagactgg gcaatttcat tggtgtggtg tggaaactct aggtcagctc
     2881 caccaccgtg gatatcaatg gtatcaccta aaatctctgt cgacatgact gaacactcaa
     2941 tatgccaacc cggacgtcca ggtccccaag gactatccca agaaatctca cctggtttgg
     3001 aagatttcca tagagcaaag tctacaggat tttccttacg agccgtttct tcatcggtac
     3061 gacctgaagc acctagctcc aaatcttcca aggttttatt agccaattta gcatagttgt
     3121 gggatttttc tacacggaaa tagacatccc cttgactctc ataggcaaag cctttctcga
     3181 tcaagtcttc cacaaaacgg atgatgtctg ccataaactc cactacacgc ggatggcgag
     3241 tcgcaggttt cacgcccaat gccgtcacat cctcacgaaa ggcagcgatg tacttatccg
     3301 caacctcctg aggcgtgata ccttcttccc tggcacggtt gataatctta tcatccacat
     3361 ctgtaaaatt ggaaatatag gcaaccttat acccacggta ctcaaaaaag cgacgaatcg
     3421 tatcaaaagc taccgtcgaa cgggcgtttc ctacgtggat atagttgtac accgttggcc
     3481 cacaaacata catcttgatc ttgccgtcct caatcgggac aaattctcgc aaatcacgag
     3541 acatggtgtc atagatttta atcataaatc ataatcagga aagctgaaat ccaagaacaa
     3601 ttagtttcat cactaaaagt tcaagtaaat ttcagtccga atatctctac acttcggaat
     3661 cccttgctcc tttctcattc agataaacca cctgagtctg tttgacaaag ccaatttttt
     3721 catacaaacg tttggcacct acattgctat cttccactgc aatctgaaat tccttgtcat
     3781 tttgctcaat tagttggttg acgagggatt ttgctaagta gcttccatag ccttttccac
     3841 gttcaggttc caatattgct aaaccgtaga ggtaattcgt attagtcgat aaatcaaccg
     3901 tacaagttcc aataacctga ccagctttta ataaaatata tagtcggctt tctggatctt
     3961 tcagagcttc agcgacatat ctatccacaa cttctctcga ttcatgttcc tctgaaaatg
     4021 cctgaaattt taattgacta atttgatcct gatacgaact atctgctaac aaaacttcaa
     4081 gatgggaaac atttgctaac ggataaggtc ttctatcctt acctaaccaa gtttctgtct
     4141 cttcatcctc gattagtccc cagttactgg caaagtcagg atgattctct aaaaaaatac
     4201 gttctgtctg aaaagtgact gaccgaatgg ggaaagaagc tgtttctctc tcaaaactag
     4261 taaacaatgc acgcgcaatc ccctgacggc gatgacctgg atgaaccagt atcgtcactt
     4321 ctacatcttg gtcatctgca tagacagtta ataaaccaac aagttcgcct ttttcataat
     4381 aaaggaaaaa ggcgggcatg tttgggtcaa aattaagcat gttagagaga tagggatcgc
     4441 gataggtacc gtcatagttt tggcaacagt taattacttt tttcgcctca gatagctcct
     4501 cttggcttaa cttgtttctt gcttgaatca tataggtatc ctctacaaac cagacgatct
     4561 gtgactggca tctttagcct gctcgagttt attgacataa tactctcgtt tttcttcgac
     4621 ttcgtgaatg acaggctcat ctttcttacc atgaagacgg acaatcttgg ccggaatacc
     4681 gacaaccgtc acgtcactag gtacatctgc tacgacaact gctgcagcac cgaccttggc
     4741 attttcacca atttccacag gcccgataac ttgggcatgg gctgatatga gggctccctt
     4801 tcgtacagtc ggatggcgtt tgccacagtc tttccctgtt cccccgagag tcactccgtg
     4861 atagagaaga acgccttttt caacaatcgc tgtctctcca atcaccagac cagaaccatg
     4921 gtcaataaaa acacctgaat caatctgggc tcctggatga atctcaatct gagtccaaaa
     4981 gcgccaaaac tgactgtaca tacgagctaa tagtttgaag ccgtgcttcc agagaaaatg
     5041 cgagagacgg tgggccgcca aggccttgac acctggataa gtcagcaaaa cctccaaagt
     5101 ggtgcgggcc gctggatcat tttcttttac aatatcaatg gtttcgcgcc accaccccat
     5161 acatttctcc ttttcttatt ctgaatcttt tgatgtttct gtaaattctt tcttaggttt
     5221 gtaatccttt tgatgacgtg ggcggtgagg gcgctcagac ttttcacctt tttcatcatg
     5281 ctcaggtttt ggcggacgag gtagaagagc cttcatagag gcatcgatac ggcctttttc
     5341 atcaattttg ataaccttaa catcaacttc atccccgatt tctaccaaat cctctacacg
     5401 attggtacga gtccaagcca tctcagagat atgaacaagg gcatctgtct tatcaaagag
     5461 gttaacaaag gcaccaaatt tctcgatacg aacgacttta gcacggtaaa cttcatccac
     5521 tttggcttca cgaaccaaac cagcaataat ttctttggca cggttaatag catcttggtc
     5581 actagagtag atagacacat ttccttcttc gtctatatca atcttaacac ctgtttcagc
     5641 gataatcttg tcgatggttt ctccaccctt accgatgaca atcttaatct tgtccacatc
     5701 aatcttgatc gtatcaattt tcggagcagt tggagccaat tctggacgaa cttctggaat
     5761 ggttgcttca atgatatcaa ggatttcaaa acgcgctttc ttggcttgag caagagcctc
     5821 cgtcaagatt tctgcagtaa tcccttgaat cttgatatcc atttgaaggg ctgtaatccc
     5881 atcacgagta cctgcaacct tgaagtccat atctccaaag tgatcttcca aaccttggat
     5941 atctgtcaat actgtgtagt tatttccatc tgagataagt cccatagcaa taccagctac
     6001 tggcgccttg attggcacac caccagccat aagggcaaga gttcccgcac agatagaagc
     6061 ttgagatgaa gaaccgtttg attccaaaac ttctgctact agacggatag cgtatgggaa
     6121 ttcttccaag cttggcaaga cttgagcaag agcacgctca ccaagggcac cgtgaccgat
     6181 ttcacgacga cctggcgcac cgtaacgacc tgtttcccct acagaatatt gagggaagtt
     6241 atagtggtgc ataaagcgtt tcttgtactc tggatccaaa ccatcaatga tttgagtttc
     6301 tcccatcgga gccaaggtca agactgaaag agcttgagtt tgcccacgag taaagagacc
     6361 tgaaccatgt acacgaggaa ggaagtcaac aaccgcatcc aaaggacgga tttcatcgac
     6421 cttacgacca tcaggacgca ccttgtcttc tgtaattaaa cgtcgcactt ctgcgtgttc
     6481 catttgttcc aagatttcag ccacatcacg cataatacgg tcaaattctt cgtggttcgc
     6541 atatttttct tcgtaaacgg cagtcacttg gtctttcact gcttgagttg cagcttcacg
     6601 ggccaatttc tcttctactt gaactgcctt ttggaggtca ctgttgtagg ctgcaatgat
     6661 ttcagcttgc aattcagcat ccacgtgaag caattccact tctgcttttt ctttaccgac
     6721 agcagcaacg atttcttctt ggaaggcaat caattctttg acagcttcgt gccctttaag
     6781 aagcgcttcc aacatgattt cttctgacaa ttctttggca ccagactcta ccatgttgat
     6841 agcgtgcttg gttccagcta ctgtcaattc aagaagagat tgctctgctt gttcttgact
     6901 tgggttgatg atgatttggc catctacata tcccacttgt accccagcaa ttggtccgtc
     6961 aaatggaata tctgaaatag acagtgccaa agatgaacca aacatagcag ccattggtgc
     7021 agatgcattt tcatcataag aaagcactgt attgatgact tggacttcat tacggaaacc
     7081 ttccgcaaac ataggacgaa tcggacggtc aatcaaacgc gctgtcaagg tcgcatctgt
     7141 tgaaggacgt ccttcacgtt tcataaagcc accaggaaac ttcccagccg catacatttt
     7201 ttcttcgtag ttgacttgga gtgggaagaa atccccagtt gccattttct tagacataac
     7261 ggcagcagtc aagacagttg actcaccgta acgtacgaca acagatccat ttgcttgctt
     7321 agcaacctga ccagtctcta caattaactc acgacccgca aaagtcgttt gaaacacttg
     7381 ttttgccatt ttaatcccct ttggattgat gaaattatac gccttgccta caaagatcaa
     7441 gataccaagg acgtcaaaag caaagtaaaa ataggaaact gacgaagtct tcgatgaaga
     7501 caagacagtt tatctttttt acacagcttt tcggccgtgt tcaattacac aagatatttt
     7561 ggacggttcg gcttgccgaa catttctgta gaaaaatagg aaggtgacgt cgcactcgac
     7621 gagtgctagg aagcttatct tttttcctaa gaaatgagac caaaattcaa gtcatcaaga
     7681 taccaagccg tcaagcaact caaaggaaga taggaaatcg aacgacggag cgactactcc
     7741 tagggagatt tatctttttc cacagagttg taggcaagtt cagttttcaa gatacatcat
     7801 tagaaaggtt taatactaaa gtatctaaag ctttcacgct aatcgctatc gggcgattag
     7861 ttaaatgctt tactaactct ctcgtcaaat aacatcgatt tgactcactc gtgtcgttaa
     7921 atcttacagt ttaaatgcat tgtattattt aataccttca tctttgtatc aagtacgtac
     7981 agaatttatt ttatcatatt tttcttaaaa agtgaggtct ttaccattaa aaaggaacca
     8041 ttcccctcac ctgagaagaa tggtttgctt ttattatcct agagactggt gattaaacaa
     8101 ggcatgggtt gcttgatgga tgtattttgc tgtatcagca ttattcatcg tatagagatg
     8161 cacaccggca acatcctgag ttaccaagtc cacgatttgg tccactgcat aggcaagtcc
     8221 tgctgctctg agcgactcag ggtcatgctc atacttgtct aagatggctt taaatttgcg
     8281 tggaagatgg atattctcac aagtcttcaa gagtcggaga gcctgatttc gattcagaat
     8341 tggcataatt cctgcatgaa tgggaacatc aatcccagcc aagatgcact tgtcctgaaa
     8401 atcatagaag cgctcattgt caaagaagag ctgagttacg aggctcgaac agcctgcatt
     8461 cactttcttc ttaagatttt gaatatctga aatctgattt ggcgaatctg gatgcccttc
     8521 tggatagcaa gctccaataa tatcaaagtg aggggtttgt tccttgataa actcaatcaa
     8581 gtctgttgca tagcggaaat ccttttgtgg ttccacgtct ggaataatat ccccacgaag
     8641 agccaagatt ttctgcaccc caactttgtc caagtcagca atagtttcag caaccttgtc
     8701 cttagttaga taaatagctg gcaagtgggc aatggtcgga atcgccaaat cattttggat
     8761 aaagtcagcc aaacgaaccg tcgtttcctt gatattaaat ttattattgc tggcagttac
     8821 actgataaaa tggggagcca actcctgcat atactgcaag gctgaaataa tgttaccatt
     8881 acccacggct gggtttggag ggaacacttc aaatgagagt gacggtgttt ggcgtgacat
     8941 atgtaataac cttttctagt tgatttcttt ttgaacaacc actgtatgga gagaaatcca
     9001 atcttacaat ttctcacgcg cagctttagc tgcttcaaca aggcggatca agctttcttt
     9061 tgtttctggg ataccacgtg ttttcaaacc acagtcaggg ttgatccaaa ctttcttgct
     9121 tggcacttta gcaaggatgg cttcgattgt gttgtcgatt tcgccttcat ttggtacacg
     9181 aggtgagtgg atatcgtaaa ccccaggtcc cacttctgtt tggaagtttt tcgctttgag
     9241 ttcgtccaag atttcaaggt ttgaacggct agcttcaaag gaaataacgt ctgcatccat
     9301 gttatcgata gctgggatga tatctgtaaa ttctgagtaa cacatgtgag tgtggatttg
     9361 tgtgtctggc gctactgttg agtgtaccaa gcggaaggca ggaatagccc agtcaaggta
     9421 gtcttcgtac cagtcgctac ggcggagtgg caatttttca cgaagagcag cctcgtcgat
     9481 ttggatgatt ttcacaccag cagcttcaag gtcaagtact tcatccttga tagcaagggc
     9541 gatttggaga gttgaatcct tgatagagat gtcttcacgt gggaatgacc agttaaggat
     9601 ggtaacaggt ccagtcaaca tacctttaac aggtttgttt gtacgacttt gtgcatagct
     9661 agaccattta acagtgatag ggttaagacg agtgacatca ccccagatga ttggtggttt
     9721 taccccacgc ataccgtatg attgtaccca tccattttta gagaagaggt atcctgacaa
     9781 gttttgaccg aagtactcaa ccatgtcatt acgctcaaat tcaccgtgaa caaggacatc
     9841 aaagtcaata tcttcttgcc acttgatcca ttcgtcaatc gtttcagcaa ggaaagcgtc
     9901 gtactctttt tgagacaatt cacctttacg gtaagccaaa cgtttggcac gaacttcttt
     9961 tgtttgaggg aatgaaccaa tcgttgttgt tggaagagct ggaagtttga aagcttcttc
    10021 ttggatagct tcacgttctg caaaggctgg caaacgagtg tagtctgcgt ctgtcaagcc
    10081 agcgatacgc gcacgaagtt cagcattttt accaacacgc tcagtcgcaa agagttcttt
    10141 gttggctgca agagcttctg aaccttgacc attgcggata gcatccaagt cacggatttc
    10201 atccaatttt tcaactgcaa aggcaaagtg gttcaagagt gctggttcaa attcttcatt
    10261 agcagttgta aatggcacat gaagaagtga gcaagagctt gtcaaaacga tgttttcagc
    10321 tgggatttgc tcaagaacag ccaagctctt ttcgtagttg ttgcgccaga tgtttttacc
    10381 attgacaata cctgcataga gagtcttgtc agctgggaag ccacctttaa cgagttcaag
    10441 agttttctta ccttcaacaa agtcaagacc gatagcatct actggcaagt ttacaaggtc
    10501 agcgtatacg tcacgaacat caccgaaata agtttgaaac aagacttcaa gacctttttt
    10561 gtcagccaag agtttgttgt aaaggttcaa gaagagagct ttttcttcag ctgtcaagtc
    10621 ttttacaaga gccgcttcat ccaattggat gcgagtcgca ccaaggtcag ccaatttagc
    10681 aaaaacttct tggtaagcag ccacaaagct atctacgaag tcgtctgctt tcacgccttc
    10741 ttcaaagtct gacaattgaa ggaaagtgaa gggacctaca agaacaggac gagtgttcaa
    10801 tccaagttct ttggcttctt gaaactcatc aaaaatcttg tgacctgcaa gtttgacttg
    10861 agtgtctttt tcaaatttag gaacgatgta gtggtagtta gtgttgaacc atttcttcat
    10921 tggaagggcg cgaacgtccc ctttttctcc ctggtaacca cgtcccaaag cgaagtagcg
    10981 ctcaaggtca gacaagtcca agttttgaac tgaggcaggc actacgttga aaaggaaagc
    11041 cgcatctagg aagttgtcat agtgagaaaa gtcatttgat gggatttcag tgatgccttt
    11101 ttctttgacg atgttccagt gtttagcacg caagtctttt gcggctgcaa ggagttcttc
    11161 ttctgagatt tcttttctaa agtatttttc agttgtaaat tttaattcac ggaattcgcc
    11221 caaacgaggg aaaccgatga ttgtagttga catgatgtgt cctccaaaat ttgttgttga
    11281 aactatctta acagaaaaga aagcgtctgt ataattgtaa aaaattaggc tttgatatag
    11341 tttgaaacta tatatctgtt tcggacaaaa gaaaaagact tgaagcaaac gtctcaaatc
    11401 ctttgtaatt cttactttac agctatattc caattagaat actaaaacat gttattagta
    11461 attcttataa gtgactatga cctgttatta gaaaagacta taactgattc tagtcaactt
    11521 tttccctgtt caagtgggac gattgctagt gtctttccta aactggctag gacttttaag
    11581 actgtatcca actgaggact agtctttcct gtctccatcc tagctatgac aggctggctt
    11641 attccactga cttcttccag ctttttctga ctgattcctt gttcatacct agcctcaatc
    11701 aactcgctca tgatagccac tcgcatatca ctttcaagga tttcctcctt gctaaagagc
    11761 tcagatggac atccttccaa ttactcccaa tagcactatt cttcatcact taaccctctt
    11821 tcttttacgt ctatgtattt taaaaaaaat gagcgaatta tgattcgata gattgaccag
    11881 cgggtttaaa gttggtgcta gcctatttct taagcgattt tccttttcta ggataaagca
    11941 gatcctgctt gcttaacccc aattttccac gatgaatcca atagtaaatg gttgaaattc
    12001 ccacgttaac ccctttagcc atcaccatca tttcaggcga aaatttttgg ttatgtatag
    12061 tggagaatct tttcctttag ttccttggtc aagcttgatt tcttgaccga gcgcttgcga
    12121 ttgttttcat aagactgttg agcgtagtcg gcagaataaa cctctttgaa gcgccctttt
    12181 ccaagacatt ttcggactgt cccacgcttg atttcagtgt ggatagtttg aggagctttt
    12241 ccaagtagag aggcaacttc tctatttgat tttccttctt ttttccatct ttcgattaag
    12301 cgacggctat cgattgtcaa atgtttacct tttgtagtat aattgtcttg catctctgtg
    12361 ccttttaatc atttcaatct taaattggac tttttttact tgggttgtac ttaatctata
    12421 aggaagacaa gaaaaagaat atcaatcaag taaagtcaca aagtcacatt agctccgagc
    12481 aaccattgca aattgaggta ctcacacaat gattaaaaca tttctctctg ccctttcggt
    12541 cattctcttt gttatcccta tcataactta ttcttttttt ccatcttcta atcttaatat
    12601 ttggctatct accagaccta tcttggcaca gatttatgcc ttccccttag ctactgcaac
    12661 tatggctgcc attttaagtt tcgtattttt ttccctatct ttttacaaga aaaataaaca
    12721 aatacggttt tactctggca ttttgctctt actatcgctc atattactat tattcggaac
    12781 agataaaacc ctttcttctg catcaaataa gactaaaacc ttaaaattag taacttggaa
    12841 cgtcgctaat caaatagaag cacaacatat tgagcgaatt tttagccatt ttgatgccga
    12901 tatggctata ttccctgaac tagctaccaa tatcagaggt gagcaagaaa accagagaat
    12961 caaactattg tttcatcaag ttggactttc tatggccaac tatgatattt tcacttctcc
    13021 acctaccaat agtggaatag ctcctgtgac tgtgattgtc aagaaaagtt atggtttcta
    13081 tacagaagct aaaacttttc atacaacacg gttcgggaca attgtattac attcgagaaa
    13141 acaaaatata ccagatatca ttgccttgca tactgctcct cctctgccag gtttaatgga
    13201 aatctggaag caagacttaa acatcattca taatcaattg gcttcaaaat atccaaaggc
    13261 tattattgca ggtgatttta atgcaactat gcgtcatgga gcacttgcaa aaataagctc
    13321 tcatagggac gcattgaatg cacttccacc ttttgaaaga ggaacttgga atagccaaag
    13381 tccaaaactt tttaatgcaa cgatagatca tatcttattg cctaaaaacc actactatgt
    13441 tagagattta gacattgtaa gttttcaaaa ctctgatcat agatgtattt ttacagaaat
    13501 cacattttaa ttattttata taaaatcacc cctctagtgt tcataaacta gagggggaat
    13561 ttgtatcata ctatcgttta acgcacttct gcattgactt tttcttcgag cgatgcttgg
    13621 attttttcca tatagcgtgc gacttcttcg tccgttaagc tatcttctgg attttggaag
    13681 gtcaagctat aagccattga cttcatacca agtcccaatt tctcacctga gaagacgtca
    13741 aagagtttga tatctgtcaa acgtttcacg ccggcagctt ggatagcatc tacaacttct
    13801 tgatgagtca cttctgcctt gaggagaagg gcaacgtcac ggctgactgc cgggaatttg
    13861 gtgatttcta caaatggagt cgctggctga agcgcagctt cgatagctga aagattaagc
    13921 tcagccacat acgtttctgg aatatcgtaa gccttggcag tgactggatg cacttggcca
    13981 aggaaaccaa gaacttggtc accgaatgaa atcacggctg tacgacctgg atgaaggcta
    14041 gcgatttcag atgttgctgt ataggttact tggagtccca aacgagtaaa tagggcttca
    14101 aggattccct tagcatagaa gaaatcaact ggaactgctg ctgtttggaa atctttttca
    14161 gcaaccaagc ctgtcaaggc aaaggcaaaa ctgttgattt catttggaag ttcttctttt
    14221 ggattacctg tttgttcaaa gacttttcca atctcgtaaa gggccaagtt tttattctta
    14281 cgagccacgt tgtaggcaac ggtatcaagg atacctgaaa tcatattttg acggaggact
    14341 gaacgatcca cagtcattgg ccacatgagt tccgtaaggt tacttggttg agccgtaaac
    14401 tcaactgctt tttcaggagt tgttagagta taggtgatga tttctgtcaa acctgctcct
    14461 tcagcaatag tacgaacttg acggcggagt ttttgtgtgg ctgtcaattc acctgctgta
    14521 ccatcgtctt ttggtagact agttggcaag cggtcataac catagatacg agcaatttct
    14581 tcaaagaggt cagcttcgat tgtgatatcc caacgacgac gtgggactct gactgtaaag
    14641 ctgtctgcat ttccagaaag accaaagcca agacgacgga agacgtcttc tacatcagca
    14701 taagacagct cagttccgag gacacgatta acatcagcaa gggttgaaga aacttctaca
    14761 tctgaagtat caagctcacc cgctgaaacg atgcccttac gcaccgtcgc acctgcaagt
    14821 tccgcaatca ggctagctgc cgcatcaagg gcttcattaa ctgttgccac attaattcct
    14881 ttttcaaagc gagaagatga ctcagaacga aggttcaggc gaccacttgt cttacggata
    14941 gatttgccat tgaaaacagc agcttcaagg acaacacgac tagatttttc agagatttct
    15001 gttgcttgac cacccatgac acctgcaagg gctactggct tgtctgcgac agtgatgact
    15061 aggtcattca cgtccaagtc acgttcttca ccgtccaagg tcaccaattt ttcaccagca
    15121 cgcgcttcac gcacacggat gtcagtccct tcaaagttat ccaagtcaaa ggcatgcatt
    15181 ggttgaccaa aatagagcag gatgtagttg gtcacgtcca ctacgttatt gatgggacgg
    15241 attccttcgt tcatgagaag attttgcaac cattgtggac ttggtgcgat ggtcacattg
    15301 tccaagatac gagctgcata gtaaggcgcc ttgtctgtct caatgctgac agaaagggca
    15361 tcttccgcag cttcattagt ttctgttaga gtaaattctt taaagttgac tgccttgtca
    15421 tagatggctg ccacttcgtg agccactcca cacatagaaa gggcatctgc acggtttggt
    15481 gtgatggaaa gttcgatgat ttcatcatcc aagtctaggt aagaaaagac ttcctcacct
    15541 ggcacggcat cttcaggcaa gatttggatg ccatctgcga attccttagg cacaactgag
    15601 tcagaaattc ccaattcacc aagtgaacag atcattccaa gtgactccaa accacggatt
    15661 tttccttttt tgattttgta gttatcagcg atacgagctc ctggaagagc caccatgacc
    15721 ttgatcccag cacgcacatt tggggcacca caaacgatct gacgctcttc ttcgccaacg
    15781 ttaacctgac aaacatggag gtgagtctct ggcacatctt cgcaagacaa gacctcaccg
    15841 acgacaattt ttgagagacc agcagctggt gattcgacac cctctacctc gattcctgta
    15901 gttgacattt tttcagccaa ctcttgtgat ggcacatcaa tgtccaccaa ttcttttaac
    15961 catttataag atataagcat aatttagttc tccagaatga ccattgccac actggttctt
    16021 ttcctttcct atcatttcaa tagaagaatc ctcttcttac cttaatttct ttctcagtaa
    16081 ccaatccgta tctacttttt gaccaaccat aaaatgatgt tggctaaatt tttcaaaacc
    16141 atatcgatta taaaacgctt gagcttttgt attatgctcc caaacaccta gccaagccca
    16201 agaaaaacta ttttttgtag caagttcaag tgcgaattca aacagttgct tacctagtcc
    16261 aaatccttgg aatttttgta gcacatagag gcgttgaatt tcaaaagcgt cctctaattc
    16321 tctctcagtt tgagcacttc cccagttgac tttgagaaaa ccagctatct cctcctcatg
    16381 cataatgaaa taggtttcag agtcaggatt tcccaactca gttgacaaag ttttcagact
    16441 ataagcctct tcaaagtatt cctgtaactg ctcttccgta ttatcatacg caaaggtttc
    16501 acgaaaggct tgtttggcaa ttttagccaa cacctcaaca tctgccattt ctacttttct
    16561 aatcattatt taaactgttc tgagaagcgg acatctcctt ggtagaatcc acggatatcg
    16621 ttgattccat aacggagcat agctacacgc tcttgtccaa gaccaaaggc aaaaccagag
    16681 tatacagtcg catcgatacc actcatttca aggacacgtg ggtgaaccat accggctccc
    16741 ataatttcga tccaacctgt tttcttacat acgttacagc cttctccacc acacttgaag
    16801 caagaaacat ccacctcaac agatggctct gtgaatggga agtaagatgg acgcaaacga
    16861 atttgacgct cttcaccaaa cattttttgg acaatcaact gaagcgttcc ttgaagatca
    16921 gccatagaga tatttttccc aactaccaag ccttcgattt ggtggaattg gtgactgtgg
    16981 gtcgcatcgt ccgtatcgcg acggaagaca cgccctggcg agatcatctt caaaggacct
    17041 ttagaaaaat catgggcatc catagcacgc gcctgaactg gagacgtgtg ggtacggagc
    17101 aagatttctt cagtgatata gaaagtatcc tgcatatcac gagctgggtg gtcttttgga
    17161 aggttcatac gttcaaagtt atagtagtct tgctccactt caaaaccatc cacgacttga
    17221 taacccatac cgatgaagat atcttcgatt tcttcactgg tttgtgtcaa aacgtgacgg
    17281 tgaccagtcg caactggacg acctggaagc gtcacatcga tactctcgct agccagttga
    17341 gccgcgactt tcttttcttc caagagctta gctgtttctt caaaagcagc tgtcaagaca
    17401 tcacgagctt cattgacgtg tttcccgatg attggacgca tctcagcaga aacatctttc
    17461 atccctttga ggatttcagt gagcgaaccc tttttaccaa ggacagagac acgcaaatct
    17521 tgcatctctt tttcatttcc agcagtaatc tgcttcaagc tagtcagcgt ttcttcgcga
    17581 agcgctttta attgttcttc aatagttgac atatttcctc catcagtctc tcgtagataa
    17641 aaagaaaacc acatgccaaa aactccactc ggagcgttga cacgcggtac catccgtttt
    17701 catctgacaa gtcagacctt catttctaaa tccatgcgca agtgaattca cccagctttc
    17761 atatagagag cttgcagtca cggctctcct ccctgatata cttcccttgg gctactagtc
    17821 tttcagattt ctattcaatt accacttagt ttatcagatt tttaccattc ttgcaagacc
    17881 tatcttactt ctgcttgtta gcttattctt atctaacttt atagcggatt gaaataagat
    17941 ga
//
LOCUS       DAVLTG010000037        17927 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLTG010000037 DAVLTG010000000
VERSION     DAVLTG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.038"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            100..1575
                     /locus_tag="VYN12_001443"
     CDS             100..1575
                     /locus_tag="VYN12_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1415813.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1925..8626
                     /locus_tag="VYN12_001444"
     CDS             1925..8626
                     /locus_tag="VYN12_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1415814.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8874..9730)
                     /locus_tag="VYN12_001445"
                     /pseudo
     CDS             complement(8874..9730)
                     /locus_tag="VYN12_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9941..10300)
                     /locus_tag="VYN12_001446"
     CDS             complement(9941..10300)
                     /locus_tag="VYN12_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1415815.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            10392..11348
                     /locus_tag="VYN12_001447"
                     /pseudo
     CDS             10392..11348
                     /locus_tag="VYN12_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11332..11889
                     /locus_tag="VYN12_001448"
     CDS             11332..11889
                     /locus_tag="VYN12_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1415816.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11882..12136
                     /locus_tag="VYN12_001449"
     CDS             11882..12136
                     /locus_tag="VYN12_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415817.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12148..14202
                     /locus_tag="VYN12_001450"
     CDS             12148..14202
                     /locus_tag="VYN12_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1415818.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14381..15241
                     /locus_tag="VYN12_001451"
     CDS             14381..15241
                     /locus_tag="VYN12_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1415819.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            15452..16162
                     /gene="ccdA2"
                     /locus_tag="VYN12_001452"
     CDS             15452..16162
                     /gene="ccdA2"
                     /locus_tag="VYN12_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1415820.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16182..16748
                     /locus_tag="VYN12_001453"
     CDS             16182..16748
                     /locus_tag="VYN12_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1415821.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16759..17871
                     /gene="msrB"
                     /locus_tag="VYN12_001454"
     CDS             16759..17871
                     /gene="msrB"
                     /locus_tag="VYN12_001454"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1415822.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5405 a         3406 c         3941 g         5175 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacat ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc catcttagaa atgggtggac ctgtcatcat gttgatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat tacagacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacgt agtgatgctt gctatgaaga aaaccgatac acttgatgtc
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt cgaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccgcaggtt gctaaaaaca cagttttgag gttgtagata agactgacga
     1681 agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca gctcaaaaca
     1741 tggttttgag gttgtagatg aaactgacga agtcagtaat catatctacg gcaaggcgac
     1801 gctgacgaag tttgaattgg attttcgcag agtgtaaatt gttgaaacta ggttgtcata
     1861 ccatgtatac cacttgggct ttggtagtag ctaactgcac taaatataat ataaggaggg
     1921 ttttatgggg aaaggccatt ggaatcggaa aagagtttat agcattcgta agtttgctgt
     1981 gggagcttgc tcagtaatga ttgggacttg tgcagttcta ttaggaggaa atatagctgg
     2041 agaatctgta gtttatgcgg atgaaacact tattactcat actgctgaga aacctaaaga
     2101 ggaaaaaatg atagtagaag aaaaggctga taaagctttg gaaactaaaa atgtagttga
     2161 aaggacagaa caaagtgaac ctagttcaac tgaggctatt gcatctgaga agaaagaaga
     2221 tgaagccgta actccaaaag aggaaaaagt gtctgctaaa ccggaagaaa aagctccaag
     2281 gatagaatca caagcttcaa gtcaagaaaa accgctcaag gaagatgcta aagctgtaac
     2341 aaatgaagaa atgaatcaaa tgattgaaga caggaaagtg gattttaatc aaaattggca
     2401 ctttaaactc aatgcaaatt ctaaggaagc cattaaacct gatgcagacg tatctacgtg
     2461 gaaaaaatta gatttaccgt atgactggag tatctttaac aatttcgatc atgaatctcc
     2521 tgcacaaaat gaaggtggac aactcaacgg tggggaagct tggtatcgca agactttcaa
     2581 actagatgaa aaagacctca agaaaaatgt tcgccttact tttgatggcg tctacatgga
     2641 ttctcaagtt tatgtcaatg gtcagttagt ggggcattat ccaaatggtt ataaccagtt
     2701 ctcatatgat atcaccaaat accttcacaa agatggtcgt gagaatgtga ttgctgtcca
     2761 tgcagtcaac aaacagccaa gtagccgttg gtattcagga agtggtatct atcgtgatgt
     2821 gactttacaa gtgacagata aggtgcatgt tgagaaaaat gggacaacta ttttaacacc
     2881 aaaacttgaa gaacaacaac atggcaaggt tgaaactcat gtgaccagca aaatcgtcaa
     2941 tacggacgac aaagaccatg aacttgtagc cgaatatcaa atcgttgaac gaggtggtca
     3001 tgctgtaaca ggcttagttc gtacagcgag tcgtacctta aaagcacatg aatcaacaag
     3061 cctagatgcg attttagaag ttgaaagacc aaaactctgg accgttttaa atgacaaacc
     3121 tgccttgtac gaattgatta cgcgtgttta ccgtgacggt caattggttg atgctaagaa
     3181 ggatttgttt ggttaccgtt actatcactg gactccaaat gaaggtttct ctttgaatgg
     3241 tgaacgtatt aaattccatg gagtatcctt gcaccacgac catggggcgc ttggagcaga
     3301 agaaaactat aaagcagaat atcgccgtct caaacaaatg aaggagatgg gagttaactc
     3361 tatccgtaca acccacaacc ctgctagtga gcaaaccttg caaatcgcag cagaactagg
     3421 tttactcgtt caggaagagg cctttgatac gtggtatggt ggcaagaaac cttatgacta
     3481 tggacgtttc tttgaaaaag atgccactca cccagaagct cgaaaaggtg aaaaatggtc
     3541 tgattttgac ctacgtacca tggtcgaaag aggcaaaaac aaccctgcta tcttcatgtg
     3601 gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc cactctttag caactgttaa
     3661 acgtttggtc aaggttatca aggatgttga taagactcgc tatgttacca tgggagcaga
     3721 taaattccgt ttcggcaatg gtagcggagg gcatgagaaa attgctgatg aactcgatgc
     3781 tgttggattt aactattctg aagataatta caaagccctt agagctaagc atccaaaatg
     3841 gttgatttac ggttcagaaa catcatcagc aacccgtaca cgaggaagtt actatcgccc
     3901 tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat tatgaacagt cagattatgg
     3961 aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca tggacttttg accgtgacaa
     4021 cgctggctat gctggacagt ttatctggac aggtacggac tatattggtg aacctacacc
     4081 atggcacaac caaaatcaaa ctcctgttaa gagctcttac tttggtatcg tagatacagc
     4141 cggcattcca aaacatgact tctatctcta ccaaagccaa tgggtttctg ttaagaagaa
     4201 accgatggta caccttcttc ctcactggaa ctgggaaaac aaagaattag catccaaagt
     4261 agctgactca gaaggtaaga ttccagttcg tgcttattcg aatgcttcta gtgtagaatt
     4321 gttcttgaat ggaaaatctc ttggtcttaa gactttcaat aaaaaacaaa ccagcgatgg
     4381 gcggacttac caagaaggtg caaatgctaa tgaactttat cttgaatgga aagttgccta
     4441 tcaaccaggt accttggaag caattgctcg tgatgaatct ggcaaggaaa ttgctcgaga
     4501 taagattacg actgctggta agccagcggc agttcgtctt attaaggaag accatgcgat
     4561 tgcagcagat ggaaaagact tgacttacat ctactatgaa attgttgaca gccaggggaa
     4621 tgtggttcca actgctaata atctggttcg cttccaattg catggccaag gtcaactggt
     4681 cggtgtagat aacggagaac aagccagccg tgaacgctat aaggcgcaag cagatggttc
     4741 ttggattcgt aaagcattta atggtaaagg tgttgccatt gtcaaatcaa ctgaacaagc
     4801 agggaaattc acccttactg ctcactctga tctcttgaaa tctagtcaag tcactgtctt
     4861 tactggtaag aaagaaggac aagaaaagac tgttttgggg acagaggtgc caaaagtaca
     4921 gaccattatt ggagaggcac ctgaaatgcc taccactgtt ccgtttctat acagtgatgg
     4981 tagtcgtgca gaacgtcctg taacctggtc ttcagtagat gtgagcaagc ctggtattgt
     5041 aacggtgaaa ggtatggctg acggacgaga agtagaagct cgtgtagaag tgattgctct
     5101 taaatcagag ctaccagttg tgaaacgtat tgctccaaat actgacttga attctgtaga
     5161 caaatctgtt tcctatgttt tgactgatgg aagtgtacaa gagtacgaag tagatagctg
     5221 ggagattacg gaagtagata aagccaaact ttcagtagct ggatcacgta ttcaaatgac
     5281 tggtcagtta gctggagaaa ctattcatgc aacccttgtg gtagaagaag gaaatgctgc
     5341 agcacctgta gtgccaactg ttactgttgg aggtgaagca gtaacaggtc ttactagtcg
     5401 acaaccaatg caatatcgta ctctatctta tggtgcccaa ttgccagaag tcacagcaag
     5461 tgctgaaaat gctgatgtga cagttcttca agcaagcgca gcaaacggca tgcgtgcaag
     5521 catatttgtt cagcctaaag atggtggccc tcttcaaacc tatgcaattc aattcctaga
     5581 agaagcacca aaaattgctc acttgagctt gcaagtggaa aaagctgaca gtctcaaaga
     5641 agaccaaact gtcaaattgt cggttcgagc tcactatcaa gatggaacgc aagctgtatt
     5701 accagctgat aaagtaacct tctctacaag tggtgaaggg gaagtcgcaa ttcgtaaagg
     5761 aatgcttgag ttgcataagc caggagcagt cactctcaaa gcggaatatg agggagctaa
     5821 aggccaagtt gaactcacta tccaagccaa tactgagaag aagattgcgc aatctatccg
     5881 tcctgtaaat gtagtcacag atttgcatca aaaacctact cttccaacaa cagtaacggt
     5941 tgagtatgac aaaggtttcc ctaaagctca caaagtcact tggcaagcta ttccgaaaga
     6001 aaaactagac tcctatcaaa catttgaagt actaggtaaa gttgaaggaa ttgaccttga
     6061 agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt gaagaagtca gtgtgacaac
     6121 tccaatcgca gaagcaccac aattaccaga aagtgttcgg acatatgatt caaatggtca
     6181 cgtttcatca gctaaggttg catgggatgc gattcgtcca gagcaatacg ctaaggaagg
     6241 tgtctttaca gttaatggtc gcttagaagg tactcaatta acaactaaac ttcatgttcg
     6301 cgtatctgct caaactgagc aaggtgcaaa catttctgac caatggaccg gttcagaatt
     6361 gccacttgcc tttgcttcag actcaaatcc aagcgaccca gtttcaaatg ttaatgacaa
     6421 gctcatttcc tacaataacc aaccagccaa tcgttggaca aactggaatc gtactaatcc
     6481 agaagcttca gtcggtgtcc tattcggaga ttcaggtatt ttgagcaaac gttcagttga
     6541 taacttaagc gttggcttcc atgaagacca tggagttggt gcaccgaagt cttatgtgat
     6601 tgagtattat gttggtaaga ctgtcccaac agctcctaaa aaccctagtt ttgttggtaa
     6661 tgaggaccat gtctttaatg attctgccaa ctggaaacca gttactaatc taaaagcccc
     6721 tgctcaactc aaggctggag aaatgaacca ctttagcttt gataaagttg aaacctatgc
     6781 tgttcgtatt cgcatggtga gagcagacaa caaactagga acgtctatca cagaggtaca
     6841 aatctttgcg aaacaagttg cggcagccaa gcaaggacaa acaagaatcc aagttgacgg
     6901 taaagactta gcaaacttca accctgattt gacagactac taccttgagt ctgtagatgg
     6961 aaaagttacg gcagtcacag caagtgttag caacaatggc ctcgctaccg tcgttccaag
     7021 cgttcgtgaa ggtgagccgg ttcgtgtcat cgcgaaagct gaaaatggcg acatcttagg
     7081 agaataccgt ctgcacttca ctaaggataa gaacttactt tctcataaac cagttgctgc
     7141 ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt gaattgccga ctaaggttcc
     7201 agtttacttc acaggtaaag acggctacga aacaaaaaac ctgacagttg aatgggaaga
     7261 agttccagcg gaaaatctga taaaagcagg tcaatttacc gttcgaggcc atgtccttgg
     7321 tagtgatctt gttgctgagg tcactgtacg agtgacagac aaactaggcg aagctctttc
     7381 agataaccct aactatgatg aaaacagtaa ccaggccttt gcttcagcaa ccaatgatat
     7441 tgacaaaaac tctcatgacc gcgttgacta tctcaatgac ggagatcatt cagaaaatcg
     7501 tcgttggaca aactggtctc caacaccatc ttctaatcca gaagtatcag cgggtgtgat
     7561 cttccgtgaa aatggtaaga ttgtagaacg gactgttgct caagccaaac ttcacttctt
     7621 tgcagatagt ggtacggatg caccaactaa actcgtttta gaacgctatg tcggtccaga
     7681 gtttgaagtg ccaacctact attcaaacta ccaagcctac gacgcagacc atccattcaa
     7741 caatccagaa aattgggaag ctgtgcctta tcgtgcggat aaagacatcg cagctggtga
     7801 tgaaatcaac gtaacattta aagctgtcaa agccaaagct atgagatggc gtatggagcg
     7861 taaagcagat aagagcggtg ttgcgatgat tgagatgacc ttccttgcac caagtgaatt
     7921 gcctcaagaa agcacgcaat cgaagattct tgtagatgga aaagaacttg ctgatttcgc
     7981 tgaaaatcgt caagactatc aaattaccta taaaggtcaa cggccaaaag tctcagttga
     8041 agaaaacaat caagtagctt caactgtggt agatagtgga gaagatagcc ttccagtact
     8101 tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa taccgtatcc agttgactaa
     8161 ggaaaaacca gtttctgaga agacagttgc tgctgtacaa gaagatcttc caaaactcga
     8221 atttgttgaa aaagatttgg cctacaagac agttgagaaa aaagattcaa cactgtatct
     8281 aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa gaacgtatct ttacagcgat
     8341 taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg gtagaagctc cgacagaccg
     8401 catcgtcttg gttggaacca aaccagtagc tcaagaagct aaaaaaccac aagtgtcaga
     8461 aaaagcagat acaaaaccaa ttgattcaag tgaagctagt caaactaata aagcccagtt
     8521 accaaataca ggtagtgcgg caagccaagc agcagtagca gcaggtttag ctcttctagg
     8581 tttgagtgca ggattagtag ttactaaagg taaaaaagaa gactagaaat tttgatacct
     8641 tctttatcat taaagaccaa agaaaaactc ttgtcctaaa tagaagataa agagtctgga
     8701 acaaaatagt tctcaaccac aaaaaagcta gatatttcca attgcggaac tctagctttt
     8761 taattttgag tcgttctctt attgtatagt agattgaaac tagagtagta cacttctact
     8821 tctaaaacat tgttagaaat cgatttgact gtccttatcg atttgtcctg ttcttatttc
     8881 atttcactat gttttaggag gttattggcc ataagtacca atcccatgtc aattctcact
     8941 tgacgcttgc ctctcagatt acatctcttg taacccaaac aagcctttat ctgcccaaag
     9001 acaggttcta catcaatctt gcgttgagcg aaaatctgtc tatcttgggg agataaaagc
     9061 gcctgacatt ctttagcttt caagttttga tagcgttcgt tcatatacaa tcccttttga
     9121 ggggctgatt caggttcatc agcgtagtaa accttgattt cctgttgaaa gtctgtctgt
     9181 gttttctggt acttgatatg gtgaaaacga tagcaccagc catcaggatg tatgtagcta
     9241 tcctccttgt cattatagtg ccaattcgct aagtttttag ctgactgttt ataccctctc
     9301 ttttgttcct tatcaaacat ggcatattta atcagaaggg gagtgatttc ttcttgaaaa
     9361 tagacttgta tctgttcttg aagtttggcg gagaatttct ctgtcgtttt cttccacaca
     9421 aaactatact tgttggcatt ggattcaatc ttagttccgt caataaacaa acaatctaag
     9481 gtcactaact cttccatttt tcaatttttc gaccagagaa aatcccttgt gaataggcaa
     9541 atagaagagt agatacaagc attttagggt gataagacgg gcgaccaaag gcatgatagg
     9601 aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt ttcaatagta aagacgagat
     9661 ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt tgtttgattt gtgttatagt
     9721 gaatatgcat gggatagcct ttctaaatgg tttattaagc aattctattt taccaagact
     9781 atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct tttttggata taagagacta
     9841 ttgtcccaga ctcttttctt tgtataaaat tgtatagtgt tattgtctat actattttgt
     9901 agagaaagca aaaatcccta gaaaatgctt agggattcga ctatttcatt aagaacaatt
     9961 caacaatcat ctctatatac atgataaggg ttaataaaaa tcctgtacgc cagaagaatt
    10021 tgatgaattt aggatagtaa aagctgcgtt tttttaaaag gaagaaaaag acgagaataa
    10081 tggctaggaa cgagagggct agccccagtc tagggaggaa attatgggta aaggttttag
    10141 ctgtaatcaa gtaatactca aataccaaga ctggaaaagc caaatccgca aagtttcgtc
    10201 ctagtttttt taatctaaaa agtttggtta ggataatgca gacgactaag gtcagtatca
    10261 ataataaaat agatgctaat ttcattaaaa tcatacccat attgtatcat aaaaaaaggc
    10321 taatggaaac gagaaacaga ggaatttata ggaaagtcag gcttttgaga ttgtgggtga
    10381 tttttgttat aatgaaagtt ataaaatctt atgatacctt gaatgattat tatcgaaaac
    10441 tctttggaga aaagactttt aaagtcccta ttgatgcggg atttgactgt cccaatcgtg
    10501 atggaactgt ggctcatgga ggctgtactt tttgtacggt ttccggttct ggagatgcca
    10561 ttgtagcccc agatccgcct atccgtgagc aattttataa ggaaattgac tttattcatc
    10621 gtaagtggcc agatgttcag aagtatctgg tttattttca aaattttacc aacacccatg
    10681 aaaaggtgga agttattcga gagcgttatg aacaggctat caatgagcca ggtgtggtag
    10741 gaatcaatat tggaacgcgc ccagactgtt taccagacga aaccatcgaa tatttggctg
    10801 agttatcgga gtgcatgcat gtgacggttg aattgggctt gcagactact tatgaagcaa
    10861 cctctgacct gattaaccgt gcgcattctt atgaattgta ggtggaaacg gtcaagcgtt
    10921 tgagaaagta tccaaaaatt gagattgttt cccatttgat caatggtttg cctggtgaaa
    10981 cccatgagat gatggttgaa aatgtccgcc gttgtgtcac ggataacgat attcaaggga
    11041 ttaaactgca tttgctccat cttatgacaa atactcgtat gcaacgagat taccatgagg
    11101 gacgtttaca attgatgagt caggacgaat atgtcagggt catctgtgac caactggaaa
    11161 ttattcccaa acatatcgtc atccatcgaa ttacaggaga tgcgcctagg gatatgctga
    11221 ttggtcctat gtggagcctc aataaatggg aagtcctcaa cagcattgag atggagatga
    11281 gacgtcgtgg aagtgttcaa ggatgcaagg ctgtaaaaca ggagtttgaa aatgaaaaga
    11341 ccacttgaga tggcacatga ttttttggct gaggtcgtga caaaagagga tgtcgtagtg
    11401 gatgcgacta tgggaaatgg tcatgacacg ctttttttag ccaagctagc caagcaagtc
    11461 tatgcctttg atattcagaa gcaagccttg gaaaagaccc aagagcgttt gcatcaggct
    11521 ggcttgacaa atgcccagtt aatcttgcaa ggccatgaga cactggacca gtttgtgaca
    11581 aaagctaagg cagggatttt taatttgggc tatttgccgt cagctgataa gtctgtcatc
    11641 acccgaccgc agacaacgat tgaggcatta gaaaagctat gtggcttact tgtcaaaggt
    11701 ggacgaattg ctattatgat ttactatggt catgaaggag gcgacctcga gagagatgct
    11761 gtcttggatt ttgtgatcca gttgaaccaa caagagtaca cagctgccat ttaccgaact
    11821 ttaaaccaag tcaacaaccc gccgttttta gtgatgattg aaaaattaga gagatacaga
    11881 catggataaa caatacctac acgaaaagct ggatgccatg cgccagaatt ttgttgaatc
    11941 aacctaccac gaacgagcgg tgggcgtgct agaccaagcg catatgagca aaaaaatgct
    12001 taaaatcaag aaaaaattag ttgctcttga aatggaacgg tgccagagaa aaattgagca
    12061 caaagactgt tccaagattg accaaaaaat caaagagcag aaggagatat ttgaatcctg
    12121 ttgtaaaaaa gattaaggag gacgtgcgtg gaattactga tttacctcat cctattttta
    12181 ctggtcttga ttgtctcaag tacaaccaat aagctcctac cctttttgcc tctccctttg
    12241 gtgcagattc ttttgggaat tgtgattggt ctctttttac ccaatactga ctttcacctt
    12301 aatacggagt tgtttttggc actggttatc ggccccttgc ttttccgaga ggctgaagaa
    12361 gcagatgtta cggctatttt aaaacactgg cgaatcattg tttatctcat atttccagtg
    12421 atttttatct cgaccctgag tttgggtggc ttggcccatc ttctttggtt cagccttccc
    12481 ttggcagctt gcttggctgt tggggcagcc cttggtccta cggacttggt ggcctttgcc
    12541 tctctttcgg agcgttttag ctttcctaag cgcgtgtcca atattcttaa gggcgaagga
    12601 ctcttgaatg atgcttctgg tttggtggct tttcaggtag ctttgacagc ttggacaact
    12661 ggagcttttt ctctggggca agctagcagt tcactcatct tttcaatcct aggcggtttt
    12721 ttaattggat ttttaacagc catgaccaac cgcttcctcc ataccttctt gctaagtgtg
    12781 cgtgcaacgg atattgccag tgaactttta ttagaattga gtttgcctct tgtgaccttc
    12841 tttctggcag aagaagttca tgtttcaggt attattgccg tcgtagttgc tggaatttta
    12901 aaggcaagtc gtttcaagaa aatcacgctc ctcgaagccc aagtggatac ggtgaccgag
    12961 acggtctggc atacagtgac ctttatgctc aacggttctg tctttgtgat tttagggatg
    13021 gagctggaaa tgatagcaga acctatcttg accaatccaa tctataatcc tctactttta
    13081 ttgctatctc ttatcgccct tacctttgtc ctctttgtca ttcgttttat tatgatctat
    13141 ggctattatg cctatagaac ccgacgcctc aagaaaaagc taaataagta tatgaaggac
    13201 atgtttctct tgaccttttc aggtgttaag ggaacggtgt cgattgctac gattctcttg
    13261 ataccaagta atctagaaca ggagtatcct ctcttgcttt tccttgttgc aggtgtgacg
    13321 cttgttagct ttttaacagg tctcttggtc ttgcctcatc tttctgatga agaggaagaa
    13381 agcaaggatt atctcatgca tatcgccatt ttgaatgaag taacgctaga gttggaaaaa
    13441 gagttggaag acaccagaaa taaactttcc ctctatgcgg ctattgacaa ttatcatgga
    13501 cgtattgaaa atctcatttt aagccaagaa aaccaggatg atcaagaaga ctgggctgct
    13561 ttgaaactct tgattcttag tattgaaagt gatggtttgg aacaggccta tgaagagggg
    13621 aatattagca atcgtgctta ccgagtttac caacgttatc tgaaaaatat agaacaagga
    13681 atcaatcgta aacttgcctc aagactgacc tattattttc ttgtttcctt gaggatttta
    13741 cgttttctcc ttcatgaagt ttttactctt ggaaagacct tccgtagctg gaaggacaag
    13801 gagcaaagcc gtctccgtgc tcttgattat gaccaaattg cagagctcta tcttgccaat
    13861 acagagatga ttattgaaag tttggaaaac ctgaagggag tctacagacg ctctttgatt
    13921 agttttatgc aggagtctcg tcttcgagaa acagctatta tcagcagtgg tgcctttgtc
    13981 gaacgggtta tcaatcgtgt caaacccaac aatatcgatg aaatgctgag aggctattat
    14041 ctggagcgca agttgatttt cgaatacgaa gaaaaacgat taattacaac taagtatgcc
    14101 aagaaattac gacaaaatgt aaataactta gagaactatt ccttgaagga agctgccaat
    14161 accctgccgt atgatatggt ggaattggta agaagaaatt agttaatact cttcgaaaat
    14221 ctcttcaaac cacgtcagcg tcgccttgga ttatatatgt gactgacttc gtcagtttca
    14281 tctacaacct caaagcaggg ctttgagcaa cctgcggcta gcttcctagt ttgctctttg
    14341 attttcattg agtataagat tataaatgaa ggagtatgac atgaaaaagt ggtggaaaga
    14401 gctgatagac aagcctttat taaaagcttt tttgcattat tatcaagcat cagatagtga
    14461 gttgaccagt gtcgcagtag cctactattg gttgatttcg attttccccc tgcttttggt
    14521 ggtggtcaat atcctcccct attttcagat tcctgtggga gaatttctgt gctttatgaa
    14581 agacgttctg cccccaagcc tctatgaagg tgtggaaaaa atagccagag aagttttgac
    14641 gcaaccttca acaggtttat tgagtttttc tgttttatcg gcgttatgga gtttttcaaa
    14701 atctatgaat ttcttgcaaa aagcttttaa caaggcttat ggcgtcgaaa agagtcgtgg
    14761 acttatttcc catcagatgc taagtctcct agtcagtttt ggcttgcagc tcctctttgc
    14821 gtttgccttg tttttgatct tatttggtca gatgattttg gctttacttg ctcattattg
    14881 gacaaaagat ggcattatct atcaggcttt acaagggttg gcaggtcctc tgatttacgc
    14941 cctcctcttt gctatcttgg tcatgcttta ttattttctt cccaatatat ctaacaggaa
    15001 aattagctat accctaccag gcagtgcctt tgttctctta gtgattttag gtttactaac
    15061 tctgttctct agttatctca attactatgt ccatcatttg gtggatgtcc gaattttagg
    15121 ttccgttctt cttgttgtta tgatgttttg gtttatcttg attgctaaaa ttgttatcct
    15181 aggcgcggtt atcaatgcca gtatgcagag tttgagagat ccggtcttta aaaaagacta
    15241 actatttatc cattacaaaa gcgcatagta tcaaaacttt atagaacctt gatactatgc
    15301 gcttttgtgc tttgacagtt ttttgtatag tttttgtcca agatttctaa atcatctgat
    15361 taaattccta ttttccccta tcattgtccc tgttttttcg aaaatggaag gagtataata
    15421 aatctatcaa taaaatgata ggaggaactt tatgggtcat attttctttt ttctaagtgt
    15481 ctttttggca gggattctat ccttcttttc tccttgtatc ttacctttgt taccggtcta
    15541 tacaggagtg ttactagatg ataaggatgg tgctcaggct tctagcggca aattttcaat
    15601 ctcagttact agtttattac gaactctggc ctttatagca ggaatttcct ttatatttat
    15661 tttgttgggc tatggagctg gttttttagg cgatttgctt tatgcttctt ggttccaata
    15721 tcttactggg gcaattatta tccttcttgg tttgcaccaa atggagattc tacactttaa
    15781 ggggctttat aaggaaaaga ggctacaact gcaaggacag gggcaaaatg gtaagggcta
    15841 tagtcaggca tttttattgg gcttgacctt tagttttgct tggacgcctt gcgtggggcc
    15901 ggttctgggg tctgttttgg ccttggcggc ttcaggtggt tcaggagctt ggcagggagc
    15961 tggtctcatg ttggtgtata cgctgggctt ggcgctacca ttcttgcttc tagctctgac
    16021 ctctagttat gttttgaaac atttccgaaa acttcatccc tatctcggaa tcctcaaaaa
    16081 agtgggtggt tttctcatta ttgtgatggg actcttggtt ctgtttggaa atgcttcaat
    16141 tttaagtcaa ttatttgaat aaaatggaaa ggaatatcaa tatgaaaaaa tggcaaacat
    16201 gtgttcttgg agcaggttcg ctcctttgtt tgacggcttg ttcaggcaag tccgtgacta
    16261 gtgaacacca aacgaaagat gaaatgaaga cggagcagac agctagtaaa acaagcgcag
    16321 ctaaagggaa agaggtggct gattttgaat tgatgggagt agatggcaag acctaccgtt
    16381 tatctgatta caagggcaag aaagtctatc tcaaattctg ggcttcttgg tgttccatct
    16441 gtctggctag tcttccagat acggatgaga ttgctaaaga agctggtgat gactatgtgg
    16501 tcttgacagt agtgtcacca ggacataagg gagagcaatc tgaagcggac tttaagaatt
    16561 ggtataaggg attggattat aaaaatctcc cagtcctagt tgacccatca ggcaaacttt
    16621 tggaaactta tggtgtccgt tcttacccaa cccaagcctt tatagacaaa gaaggcaagc
    16681 tggtcaaaac acatccagga ttcatggaaa aagatgcaat tttgcaaact ttgaaggaat
    16741 tagcctagga ggtgtcttat gaatgataag ttaaaaatct tcttgttgct aggagtattt
    16801 tttctagcca taaccggttt ctatgttcta ttgatacgaa atgcagggca gacagatgcc
    16861 tcgcaaattg aaaaggcggc agttagccaa ggaggaaaag cagtgaaaaa aacagaaatt
    16921 agtgaagacg cagacttgca cgaaatttat ctagctggag gttgtttctg gggagtggag
    16981 gaatatttct cacgcgttcc cggggtgacg gatgccgttt caggctatgc aaatggtaga
    17041 ggagaaacaa ccaagtacga attaattaac caaacaggtc atgcagaaac cgtccatgtc
    17101 acctatgatg ccaagcaaat ttctctcaag gaaatcctgc ttcactattt ccgcattatc
    17161 aatccaacca gcaaaaataa acaaggaaat gatgtgggga cccagtaccg tactggtgtt
    17221 tattacacag atgacaagga tttggaagtg attaaccaag tctttgatga ggtggctaag
    17281 aaatacgatc aacctctagc agttgaaaag gaaaacttga agaattttgt ggtggctgag
    17341 gattaccatc aagactatct caagaaaaat ccaaatggct actgccatat caatgttaat
    17401 caggcggcct atcctgtcat tgatgccagc aaatatccaa aaccaagtga tgaggaattg
    17461 aaaaagaccc tgtcacctga ggagtatgca gttacccagg aaaatcaaac agaacgagct
    17521 ttctcaaacc gttactggga taaatttgaa tccggtatct atgtggatat agcaactggg
    17581 gaacctctct tttcatcaaa agacaaattt gagtctggtt gtggctggcc tagttttacc
    17641 caacccatca gtccagatgt tgtcacctac aaggaagata agtcctacaa tatgacgcgt
    17701 atggaagtgc ggagccgagt aggagattct caccttgggc atgtctttac ggatggtcca
    17761 caggacaagg gcggcttacg ttactgtatc aatagcctct ctatccgctt tattcccaaa
    17821 gaccaaatgg aagaaaaagg ctacgcttat ttactagatt atgttgatta atactcttcg
    17881 aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tagggtt
//
LOCUS       DAVLTG010000038        17281 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLTG010000038 DAVLTG010000000
VERSION     DAVLTG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.039"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            74..757
                     /gene="rpiA"
                     /locus_tag="VYN12_001455"
     CDS             74..757
                     /gene="rpiA"
                     /locus_tag="VYN12_001455"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1415823.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            771..1982
                     /locus_tag="VYN12_001456"
     CDS             771..1982
                     /locus_tag="VYN12_001456"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1415824.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            1984..2517
                     /locus_tag="VYN12_001457"
                     /pseudo
     CDS             1984..2517
                     /locus_tag="VYN12_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285096.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            2541..3350
                     /locus_tag="VYN12_001458"
     CDS             2541..3350
                     /locus_tag="VYN12_001458"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1415825.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            3826..4221
                     /locus_tag="VYN12_001459"
     CDS             3826..4221
                     /locus_tag="VYN12_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1415826.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            4231..4806
                     /locus_tag="VYN12_001460"
     CDS             4231..4806
                     /locus_tag="VYN12_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1415827.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            4831..5343
                     /locus_tag="VYN12_001461"
     CDS             4831..5343
                     /locus_tag="VYN12_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1415828.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            6001..6711
                     /gene="deoD"
                     /locus_tag="VYN12_001462"
     CDS             6001..6711
                     /gene="deoD"
                     /locus_tag="VYN12_001462"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1415829.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(6734..7258)
                     /locus_tag="VYN12_001463"
     CDS             complement(6734..7258)
                     /locus_tag="VYN12_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1415830.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(7311..7547)
                     /locus_tag="VYN12_001464"
     CDS             complement(7311..7547)
                     /locus_tag="VYN12_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1415831.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(7615..8535)
                     /locus_tag="VYN12_001465"
     CDS             complement(7615..8535)
                     /locus_tag="VYN12_001465"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1415832.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            8725..9129
                     /locus_tag="VYN12_001466"
     CDS             8725..9129
                     /locus_tag="VYN12_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415833.1"
                     /translation="MKILKRYILELCFILSFALPFTKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSILIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            9345..9926
                     /locus_tag="VYN12_001467"
     CDS             9345..9926
                     /locus_tag="VYN12_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1415834.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            9923..11200
                     /locus_tag="VYN12_001468"
     CDS             9923..11200
                     /locus_tag="VYN12_001468"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1415835.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYCPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            11218..11880
                     /gene="deoC"
                     /locus_tag="VYN12_001469"
     CDS             11218..11880
                     /gene="deoC"
                     /locus_tag="VYN12_001469"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1415836.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            11867..12256
                     /locus_tag="VYN12_001470"
     CDS             11867..12256
                     /locus_tag="VYN12_001470"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1415837.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            12346..13398
                     /locus_tag="VYN12_001471"
     CDS             12346..13398
                     /locus_tag="VYN12_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1415838.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            13542..15077
                     /locus_tag="VYN12_001472"
     CDS             13542..15077
                     /locus_tag="VYN12_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415839.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            15070..16128
                     /locus_tag="VYN12_001473"
     CDS             15070..16128
                     /locus_tag="VYN12_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415840.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KEFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            16131..17087
                     /locus_tag="VYN12_001474"
     CDS             16131..17087
                     /locus_tag="VYN12_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415841.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            17172..>17281
                     /locus_tag="VYN12_001475"
     CDS             17172..>17281
                     /locus_tag="VYN12_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415842.1"
                     /translation="MKLSCDDKVQIYELRKQGYSLEKLSNKFGINNSNLR"
BASE COUNT         5059 a         3073 c         3971 g         5178 t
ORIGIN      
        1 taaaggtact tttagatgaa ataaaagcct ttacatggta taatagaggt agctctttaa
       61 tggaggtgtt tgagtggaaa atctgaagaa aatggcaggt atcaaggctg ctgagtttgt
      121 caaggatgga atggtcgttg gacttggaac aggctcgact gcctattatt ttgtcgaaga
      181 aatcggtcgt cgtatcaagg aagaaggatt gcagattata gctgtaacga cttctagtgt
      241 gaccactaaa caggcagaag gccttaatat cccactcaaa tctattgacc aagtagactt
      301 tgtcgatgtg acagttgatg gcgcagatga agtggatagt cagtttaatg gaatcaaagg
      361 tggtggtggt gctcttctga tggagaaggt tgttgcgaca ccatcaaaag aatacatttg
      421 ggtggtggat gaaagcaagc tggtcgaaaa actaggtgct tttaaattgc cagtagaagt
      481 ggttcagtat ggtgcagaac aggtctttcg tcgttttgaa cgagctggct acaaaccaag
      541 tttccgtgaa aaagacggcc aacgttttgt gacggatatg cagaatttta tcattgacct
      601 cgccttggat gtcattgaaa atccaattgc ttttggacaa gaattggacc atgtcgttgg
      661 tgttgtggag catggtttat tcaaccaaat ggtggataag gtcatcgttg ctggacggga
      721 tggagttcag atttcaactt caaaaaaagg aaaatagaag ggggcataag atgtctaaat
      781 ttaatcgtat tcatttggtg gtactggatt ctgtaggaat cggtgcagca ccagatgcta
      841 ataactttgt caatgcaggg gttccagatg gagcttctga cacactggga cacatttcaa
      901 aaacagttgg tttgaatgtc ccaaacatgg ctaaaatagg tcttggaaat attcctcgtg
      961 aaactcctct taagactgta gcagctgaaa gcaatccaac tggatatgca acaaaattag
     1021 aggaagtatc tcttggtaag gatactatga ctggacactg ggaaatcatg ggactcaaca
     1081 ttactgagcc tttcgatact ttctggaacg gattcccaga agaaatcctg acaaaaatcg
     1141 aagaattctc aggacgcaag gttattcgtg aagccaacaa accttattca ggaacggctg
     1201 ttatcgatga ttttggacca cgtcagatgg aaactggaga gttgattatc tatacttcag
     1261 ctgaccctgt tttgcagatt gctgcccacg aagacattat tcctttggat gaattgtacc
     1321 gtatctgtga atacgctcgt tcgattaccc ttgagcgtcc tgcccttctt ggtcgcatca
     1381 ttgctcgccc ttatgtaggt gaaccaggta acttcactcg tacggcaaac cgtcgtgact
     1441 tggctgtatc tccattttcc ccaactgttt tggataaatt gaatgaggct ggtatcgata
     1501 cttatgctgt gggtaaaatc aacgatatct ttaacggtgc tggtatcaac catgacatgg
     1561 gtcacaacaa gtcaaatagt catggaattg atacactatt gaagactatg ggacttgctg
     1621 agtttgaaaa aggattctca ttcacaaacc tagttgactt tgatgccctt tacggccatc
     1681 gtcgtaatgc tcacggttac cgtgattgct tgcatgagtt tgatgaacgc ttacctgaaa
     1741 ttatcgcagc tatgagagag aatgaccttc tcttgattac tgcggaccat ggaaatgacc
     1801 caacgtatgc aggaacggat cacactcggg aatatattcc attgttggcc tatagccctg
     1861 cctttaaagg aaatggtctc attccagtag gacattttgc agatatttca gcgactgttg
     1921 ccgataactt tggtgtggaa actgctatga ttggggaaag tttcttagat aaattggtat
     1981 aagatgacgc gctatgcttt gctggtgaga ggtatcaatg ttggtggtaa gaataaggtc
     2041 gtcatggcgg agcttcgtca agaattgaca aacttgggac tggaaaaggt tgagagctac
     2101 atcaacagtg gcaatatttt ctttacttcg atagattcca aagcccaatt ggttgaaaag
     2161 ctagagactt tctttgcagt ccattatcca tttattcaga gcttttcttt actgagtcta
     2221 gaggactttg aggcggaact tgaaaatcta ccagcttggt ggagcagaga tttggcacga
     2281 aaagattttc tcttttacac tgagggtttg gatgtggacc aagtcatcgc gacagttgaa
     2341 agtttagagc tgaaagatga agtgctttat tttggaaaac ttgggatttt ctaggggaaa
     2401 ttttctgaag aatcctattc taagactgcc tatcataagt acttgctgag gtgcctttct
     2461 accgccacat tactattcgt aatgctaaaa cctttgacaa aattggtcaa atgctaaaaa
     2521 aataataaag gagacacaca atgacatttt taaacaaaat ccatgaaact gctactttcc
     2581 tgaaagaaaa gggaattgca gcccctgagt tcggtctaat ccttgggtca ggacttggag
     2641 aattggcaga agaaatcgaa aatccagttg tagtagacta tgctgagatt ccaaactggg
     2701 gccgttcaac agtagtcggt catgctggta aattggtata tggtgaactg gcaggtcgca
     2761 aggtcttggc tcttcaaggg cgtttccatt tctatgaagg gaatcctctg gaagtggtga
     2821 ctttcccagt tcgtgtgatg aaagttcttg gatgtgaagg tgttattgta accaatgcag
     2881 ctggcggtat cggatttggt cctggtacct tgatggctat ctcagaccat atcaacatga
     2941 cggggcaaaa tccattgatg ggtgaaaact tggatgactt tggcccacgt ttcccagata
     3001 tgtctagggc ctacacacca gaataccgtg ctactgccca tgaagtggct aaaaaactta
     3061 atatcaagct tgatgaaggt gtctatatcg gagttactgg tccgacttat gaaacaccag
     3121 cagaaattcg ttcctataag acactgggag cagatgcagt tggtatgtct acggttcctg
     3181 aagttatcgt ggcagcccac tctggcttga aagttctggg aatttcatgt atcactaact
     3241 ttgcggctgg tttccaagaa gaactcaatc acgaagaagt tgtagaagtg actgaacgtg
     3301 ttaaaggtga ttttaaaggc ttgcttaaag cgattcttgc tgaattgtaa gaaaaaagat
     3361 ttaaaagggg gagtgcctct gtcttttcag gattgactgc ctatccgtat taaagaagaa
     3421 acagaggaat actatgagct tcttcctgct cttataactg aaagaagcgg aagaataggt
     3481 gtgtctgatc tgatagccag cattgtgaaa gacaagattc taggatacta gcattagctt
     3541 cctagccaag cagactagta tgataaggag agatgagaat gaattgactt tctgaatttc
     3601 tcagtcttat catatatagc acaatgagat ttcgcttgag tctgcttgta aataaacgaa
     3661 aagaaagata agaaataatg aaaattggtc aacgaattat gcgctttggc ataaaaaatt
     3721 aagtatcgga gttgtatctg ttgtagtcgg ctttgatttc tagctccagc tggaatttca
     3781 gccaatgaag taaagcaaga tgtaacaact gaagtggtaa taggtgtgct agattctaag
     3841 gaggaattga aagagtcaga aaatgatgct ccaaaactag aaactcctct tagagaggag
     3901 ccaagactag ctcctcaaac gcttccggaa gcaagtgaag ttcttgaaaa caaaagggaa
     3961 gagtcaaaag tagagataac agagccagct caagcggatg acatccgcaa ggttgttggg
     4021 gaattagcca aggatataag tattactaag ttgtatatga caggtcattc tcttggaggc
     4081 tacctagctc agattgcagc ggttgaagat taccaaaaat atcctgattt ttataaccat
     4141 gtattgagga aagtgacaac tttcagtgct cctaaagtga ttacttccag aactgtttgg
     4201 gatgctaaga atggtttctg agatgttggt ttggaaagtc gtaaattagc tgttagtgga
     4261 aaaattaagc attatgtggt tgataatgac aatgttgtga ctcccttgat tcataataat
     4321 cgtgatattg ttacatttac aggtaattca cgctttaaac accgttctcg tggctatttt
     4381 gaaagtccaa tgaatgatat tcctaacttt aatattggta aacaagctac cttggataaa
     4441 catggttatc gtgatccgaa attggataaa gtgcgattct ttaagaaaca ggctctacct
     4501 caatcttcta gtcaaccaag cgctgaacca atggaaaata ttgccttagg aaaacaggtt
     4561 actcaaagtt cgacagcttt cggaggagat gctagaagag ctgtggatgg caaagtcgat
     4621 ggtaactatg gtcacaattc tgtcactcat acaaacttcc aatctaagcc ttggtggcaa
     4681 gtagatttgg ctaaagaaga aaccattcgc caaatcaata tttacaaccg aacagacact
     4741 gcccaggata gattggcaaa ctttgatgtc attcttttag acagttctgg taaagaaatt
     4801 gagtgaaaac gtataatatc tcctaaagat gtgtcagcac aaattacgat taaccataaa
     4861 aaagcgcgct atgttcggat tgggctagaa ggctataatg ccctcagtct tgcagaagtt
     4921 gaagttttcc gctttatagc tacgaatgct gaaacggcga cacaagtttc taagccagtt
     4981 caaccaatca gtcagactcc tgtgaaagat aaaacattga caattcaaca cagtggagct
     5041 tacattgccc gctactccat aacttgggaa gaagttccag tagataaaga tggaaaccaa
     5101 gttgttcgta gtcattcttg ggaaggaaac ggttgcaacc agactgcagg ttttgtcctc
     5161 aacttcccaa tcaaagaaaa tatgagaaat ctgcgagtta agattgagaa aaagacgggc
     5221 ctactatgga atagatggca aacaatctat gaaaacagac caattttagc tcaaccccac
     5281 cgtaaaatta cccattgggg tacgacattg aattccaagg tgagtgacga tgatgtcttg
     5341 taatctgatg gtacaatgac agttagtttg tctagtttat aagaaagtac tatctgagct
     5401 tgaatagaac tcaggtagct ctctgtgaaa gaacaaaatt aatactcaat gaaaatcaaa
     5461 gagcaaacta ggaaactagc cgcaggttgc tcaaagcact gctttgaggt tgtagataag
     5521 actgacgaag tcagtcacat atataatcca aggcgacgtt gacgtggttt gaagagattt
     5581 tcgaagagta taaacagaaa ggtagagcgc gtgttctaat ttgaacacga gtagaaaact
     5641 tttctaaaaa caaaaacgaa aggatgggta aactgtattc gctgaactga atacgggcga
     5701 ctctcctcta aatcaaaatt aagaaagaaa ggaattgacc ccaccctaaa agcagtggga
     5761 aaaagatagt tggtctagcg agcatcgctc actgcgccca actcctattt tcccttcgct
     5821 ttttgacggg tttggtatct ttctcaatat aaaatataaa ataaagaaag gtagagcgtg
     5881 tgttttgatt tgaacacgag cggaaaactc ggaaaataga taatctgact gaaaaatcag
     5941 gatttctcgt cggcttccta attttcagtc gttttcttct cgctctttgt atcataaatt
     6001 atgtctatcc atattgctgc tcagcagggt gaaattgctg ataaaattct tcttcctggg
     6061 gatcctcttc gtgctaagtt tattgcggag aatttccttg atgatgctgt ttgttttaac
     6121 gaagtgcgta acatgtttgg ttacactggt acttacaagg gtcactgtgt atctgtcatg
     6181 ggaactggga tgggaatgcc atctatttcg atttatgcgc gtgagttaat cgtagactac
     6241 ggtgtgaaga aattgattcg tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt
     6301 cgtgaattag ttttggcgca ggcggctgca accaactcaa acatcgttcg taatgactgg
     6361 ccacagtacg attttccaca aattgctagc tttgatttgc ttgataaagc ctaccatatc
     6421 gccaaaaaac ttggtatgac tactcacgtt gggaacgttt tgtcatctga tgtcttttac
     6481 tcaaattact ttgaaaagaa tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg
     6541 gaagcagcag ctctttacta tcttgctgcc caataccatg ttgatgcgct agctatcatg
     6601 accatctctg atagcttggt caatccagac gaagatacaa ctgcagaaga acgtcaaaat
     6661 accttcactg atatgatgaa ggttggtttg gaaaccttga ttgcagaata attatagcca
     6721 aaaaggaagc cctttatgaa ttgtaggact tccttttctt atccagaaat tgatctagtt
     6781 ctctctgatt tcgaagaata gtgactttat gtgaatattc ttggcaaagt ttttggtaat
     6841 tttctttttg agttttgcta cgcccatccc aaagaatcca tctgataaac tcccactcaa
     6901 agcgttcagg gcaatctgcc gccatacttt ctctgacttt tccacggtat ttaagataac
     6961 gcttaaaggc tctaaagaga caggtcaatg gcaaaaaatt gagaaagatg atttggtcag
     7021 cttcttgcat tcgttcttgg tagtagcacc aagaataatt accatcgatg acccaagctt
     7081 tatgcttggt gagaaagttt tttatctcgg ttaacatcca ttcgcagtca ctgtcttgcc
     7141 aaccaggttg aaattggagt gtgtccatgt gcagttttgg aatggagtag tagttagata
     7201 acttttctgc tagagttgac ttaccagaac cagaatatcc gataattgcg attttcattt
     7261 tctacctttt cctatttgga gacaaaaaaa cagcctctat ggactgtttc ttatttagca
     7321 agtttagctg aaagacgagc tttatcgcgg cttgctttgt ttttgtgaat caaaccttta
     7381 gtttctgctt tatcgatagc tgagctagca gcacggaaaa gttcttcaga tgggtttgct
     7441 tcgaaagctt ttatagcagt acgcatagct gatttttgag ctgagttctt ttcgttttgt
     7501 ttaacgttca attcagcgcg tttgatagct gatttaatgt ttgccaatgt tcttacctcc
     7561 atatttacta actataccat tatatatgaa aacttacgtt ttgacaaggg aaaattactt
     7621 ttttaagtaa atttcatcga tttcatggtt cttgctttta tgaagaatca cttctgcacg
     7681 atttctggtt ggttcaatat aattttgcag atttgtgaga ttgatactgg tccagacctg
     7741 atgggcaaag gactccactt ccccaatcgg catctgagta aaacgataat agtagctatc
     7801 agggtcgttt tgggctaggc tcagcatttt caagaaacgg tccagatacc aactttcaat
     7861 atcatccact ccagcatcta catagatgga aaagtcaaag aagtcagtga tatagagacg
     7921 atcgttttgt ggattttgaa agacattaat tccctcaaca attacaaaat cagcagcttt
     7981 gacactttgt ttcttttcgg gtacgatgtc gtaaacttca tgagaataga caggaatatc
     8041 tacatcttgt ccatttttga tgcggtccaa gaagttgaga agagcttcca tatcatagct
     8101 ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc aaggtttgat tgggatagag
     8161 aaaaccatca gttgtaacca actcaaccgt agcatctgta aacgtacggg acagtaggat
     8221 ttgaagtagg cgactggttg tggattttcc aacggcaaca ctcccagaaa ccccaataat
     8281 aaaaggttga gatttacttt cacgttggag gaaaattcct tttgaaaagg ctaaatcttc
     8341 cttagttcgc ttgtaaatct gaatcagatg agccaagggg agatagatat ctgtaacgtc
     8401 ttggagactg atttggtcat taaaactctt gatagattcc aattcttctt ctgtcaaagg
     8461 aggtgttgtc tttcgatgta aagattgcca agtctggcgg ctgatttttt caaaatgtaa
     8521 aaattcgttg gtcatttgtt tttccctaga tattttgtct atcataccat aaaaagctaa
     8581 aaaaataaag cggtttcttg aatgtggtaa gtcaatggta tatagtataa gtgatcaatt
     8641 tattgatgaa ataggagata gattctactg atttataagc ttataaaggg ggctttttag
     8701 ttcacaactt ataggaggtg tactatgaaa atcttaaaac gttacatatt ggaactctgt
     8761 tttattttaa gttttgcttt accttttaca aaaggagcca atgcagataa tggtagatgc
     8821 tttgtggaaa cctattacgg ttttactttt ttgatggaac atgctattgt aacagctgtc
     8881 tttatctgtt cgatcttaat tgctttctta ctaaaaaaac gatgggcgaa atggattgct
     8941 gctggtagtt attgcttttt agtcctatgg attgcgacag agggttattt cttccgcatg
     9001 tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca aacgtatcag
     9061 ttgggctttt atctaaacat tttgttggga attttgttga taataaagta ttttaaggtt
     9121 aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt tttatctgga
     9181 ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga gattgaagaa
     9241 aatggcttcg tgactcgctt tcttcggtct ttttcgtttt attatcaatt tgtaaacgat
     9301 ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtat tatgcagaaa
     9361 atcctgacgc tgctcacgac attcatgagt tgagagtaga gttgttggga caaaaaatga
     9421 cctttttaac ggatgcgggt gtttttagca agaaaatagt tgactttgga agtcaactct
     9481 tgctcaagtg tcttgaggtc aaccaaggag aaactgtcct tgatgtaggc tgtggttacg
     9541 gacctttggg tttgtcctta gctaaggctt atggagttca ggctactatg gttgatatca
     9601 acactcgtgc cttggattta gctcggagaa atgctgaaaa aaataatgca aaagcgacga
     9661 ttttccagtc caacatctat gaacaagttg agggacattt tgatcatgtc atttccaatc
     9721 ctcctatccg tgcgggcaag caagtcgttc atgaaatcat tgagaaaagt aaagatttct
     9781 tggaaactgg tggggatttg acaatcgtca tccagaaaaa acaaggggct ccaagtgcta
     9841 agtccaagat ggaggatgtg tttggtaatt gtgaaatcct taaaaaagac aaaggatact
     9901 atatccttag aagtgtgaaa gaatgagagc agttgattta atacaaaaaa aacgagacgg
     9961 tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtgt caggaactgt
    10021 tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa tgacgactcg
    10081 tgaaatttct gatttaacga tgaatatggt taagactggg caagagtttg acctgtcagc
    10141 cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata aggtaacctt
    10201 gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga gtggtcgtgg
    10261 tcttggccat acaggcggaa caattgataa attggagtcc attaagggct atcaagtaga
    10321 acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg tcattgggca
    10381 atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg tgaccgcaac
    10441 tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg cggcaggggc
    10501 ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga cggttgatga
    10561 ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac ggaagacagt
    10621 agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc gtctggaaat
    10681 ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc actttatttg
    10741 tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg aagaagttcg
    10801 ccaacatctt gagaatggtc aagcactggc taagtttgag gaaatggtgc aagcccaagg
    10861 tggagacttg gaagacctct attgtcctgt aaatgtagct catgtggtgg aaatccctgc
    10921 tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt atgccatgag
    10981 gctgggtgct ggtcgtgcag ttaagtctga tgccttggac tatgaaacag gaattgtttt
    11041 tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag tatacacaaa
    11101 tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa taagtgatga
    11161 agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa aaccgaaatg
    11221 aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa aaaacaaatt
    11281 gatagtttgt tgtctgaggc tagagagtat gactttgcca gtgtttgcgt taatccgacc
    11341 tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg cacagtagta
    11401 ggtttccctt tgggagcaac aacttcagcc gtgaaagcat ttgagacaaa agaagctatc
    11461 caaaatggtg cagatgagat tgatatggtg atcaatgttg gagctctcaa atcaggtaat
    11521 ttagccttgg ttgagtcaga tattcgcgca gtagtggaag caagtggtga taagttagtg
    11581 aaagtcatta ttgaagcttg ccttctgaca gaccaagaaa aaattgttgt ttgccaattg
    11641 gcccaaaaag ctggggctga ctttgttaaa acatctactg gtttttcaac tggtggtgct
    11701 acgatagcag atgttacatt aatgcgtgaa acagttggat ctgatatggg agtcaaggct
    11761 gctggtggag ctcgttctta tgcagatgct cttgcctttg tcgaagcagg tgcgacccgt
    11821 atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg cgactactga
    11881 gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt ctcactttcc
    11941 tatcggagca gttttagtag ccaaagacgg aagtgtttac acgggagtga atatcgaaaa
    12001 tgctagctat cctttgacca attgcggtga gagaacagct gtttttaagg ctatatctga
    12061 aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac cgatctcgcc
    12121 atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa aagtgacctt
    12181 agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gaattacttc catactcttt
    12241 tacagactta aactagtctg agtcgctctc tgagtggcac ggtccttgtg gccaaccaat
    12301 ccatacttgc aacatcgttg cacatcttat ttaggaggtt cagtaatgaa caagaaacaa
    12361 tggctaggtc ttggcctagt tgcagtggca gcagttggac ttgctgcatg tggtaaccgc
    12421 tcttctcgta acgcagcttc atcttctgat gtgaagacaa aagcagcaat cgtcactgat
    12481 actggtggtg ttgatgacaa atcattcaac caatcagctt gggaaggttt gcaggcttgg
    12541 ggtaaagaac acaatctttc aaaagataac ggtttcactt acttccaatc aacaagtgaa
    12601 gctgactacg ctaacaactt gcaacaagcg gctggaagtt acaacctaat cttcggtgtt
    12661 ggttttgccc ttcacaatgc agttgaagaa gcagctaaag aacacactga cttgaactat
    12721 gtcttgattg atgatgtgat taaagaccaa aagaatgttg cgagcgtaac tttcgctgat
    12781 aatgagtcag gttaccttgc aggtgtggct gcagcaaaaa caactaagac aaaacaagtt
    12841 ggttttgtag gtggtatcga atctgaagtt atctctcgtt ttgaagcagg attcaaggct
    12901 ggtgttgcgt cagtagaccc atctatcaaa gtccaagttg actacgctgg ttcatttggt
    12961 gatgcggcta aaggtaaaac aattgcagcc gcacaatacg cagccggtgc agatattgtt
    13021 taccaagtag ctggtggtac aggtgcaggt gtctttgcag aggcaaaatc tctcaacgaa
    13081 agccgtcctg aaaatgaaaa agtttgggtt atcggtgttg atcgtgacca agaagcagaa
    13141 ggtaaataca cttctaaaga tggcaaagaa tcaaactttg ttcttgtatc tactttgaaa
    13201 caagttggta caactgtaaa agatatttct aacaaggcag aaaaaggaga attccctggc
    13261 ggtcaagtga tcgtttactc attgaaggat aaaggggttg acttggcagt aacaaacctt
    13321 tcagaagaag gtaaaaaagc tgtcgaagat gcaaaagcta aaatccttga tggaagcgta
    13381 aaagttcctg aaaaataatg gatggaagtc atttcttagg aagcggccaa gggccgcttt
    13441 tttaagagtt gagacaaagt cattttgtct cagtaaagct tgctactaga caaactagca
    13501 agttttattg aaataaaata agactctgaa aggaagagca catggcacac gaaaatgtca
    13561 ttgagatgcg tgatattacc aaggtgtttg gtggatttgt tgccaacgac aaaatcaact
    13621 tgcacctacg aaaaggtgaa attcatgcac ttttaggaga aaatggggct ggtaagtcca
    13681 cgctaatgaa catgttagca ggccttcttg aaccaactag tggtgaaatc gcggtcaacg
    13741 gtcaagttgt caatctcgac tccccatcta aagcagctag cttgggaatc gggatggttc
    13801 accagcactt tatgttggtt gaagccttca cagtggctga aaacatcatt ttaggtagtg
    13861 aattgactaa aaatggtgtg ctagatatcg ctggagctag caaagaaatc aaggctcttt
    13921 ctgaacgtta tggcttagct gttgaccctt ctgccaaggt agcagatatc tcagttggag
    13981 cccaacaacg tgtagaaatt ttaaaaacac tttatagggg ggctgatatc cttatctttg
    14041 acgaaccaac ggctgttttg actccatcag aaattgatga gttgatggct attatgaaaa
    14101 atcttgtcaa agaaggaaaa tcaattatct tgattaccca caaattggat gaaattcgcg
    14161 cagtttctga ccgtgttaca gttatccgtc gtgggaaatc aattgaaacc gttgaaattg
    14221 caggggctac caatgctgat ttggcggaaa tgatggtagg acgttctgtt tcctttaaaa
    14281 cagagaagca agcctctaaa ccaaaagaag tggttttgtc tatcaaagat ttggtggtca
    14341 atgaaaaccg tggtgttcca gctgttaaaa atctgtcctt ggatgttcgt gctggagaga
    14401 ttgttggtat tgcggggatt gatggaaatg gtcagtctga actgattcaa gccattacag
    14461 gtcttcgtaa ggttgaatct ggtagcattg agctaaaagg agattcaatt gtaggcttgc
    14521 acccacgtca gattacagaa ctaagtgttg ggcacgttcc agaagaccgt caccgtgatg
    14581 gcttgatttt ggaaatgatg atatctgaaa atattgccct tcaaacctac tataaagaac
    14641 cacatagtaa aaatggaatt ttgaattatt caaatattac ttcttatgct aaaaagctga
    14701 tggaagagtt tgatgttcgc gctgccagtg aattagttcc tgcagctgca ctctcaggag
    14761 gaaatcaaca aaaagcaatt attgctcgtg aaattgatcg agatcctgat ctccttatcg
    14821 ttagccagcc aactcgtggg ttggatgtcg gtgccattga gtatatccac aaacgcttga
    14881 ttgaagagcg tgataatggc aaggctgtcc ttgttgtcag ctttgaattg gatgagattt
    14941 taaacgtctc agaccgtatt gccgttatcc acgatggtaa gattcaaggt attgtatcac
    15001 cagaaacaac caataaacaa gaacttggtg tcttgatggc tggtggaaac ttgggaaagg
    15061 agaagagtga tgtctaaaaa attacaacaa atttcggttc ccttgatttc tgtatttcta
    15121 ggaattttac tcggagccat tgtcatgtgg atcttcggtt atgatgctat ttggggctac
    15181 gaagaattgt tctatacagc ctttggcagt ctgcgtggga ttggagaaat cttccgtgct
    15241 atgggtcctc tggtcttgat tggtcttggt tttgcggttg ccagtcgagc tggtttcttt
    15301 aacgtcggac ttcctggtca ggctttggca ggttggattc tcagtggttg gtttgcgctg
    15361 tcgcatccag atatgccccg tcccttgatg attctagcaa ccatcgtgat tgccttgatt
    15421 gctggtggga ttgtcggagc gattccaggt attcttaggg cctatctagg gacgtcagag
    15481 gttattgtaa ccatcatgat gaactacatt gtcttgtatg tagggaatgc ctttatccat
    15541 gctttcccta aagaattcat gcaaagtaca gattcgacca ttcgtgttgg ggctaatgca
    15601 acctatcaga caccttggtt ggctgagttg actggtaact cacggatgaa tattggtatt
    15661 ttctttgcca tcattgccgt tgcagttatt tggttcatgc tcaagaaaac aactcttggt
    15721 tttgaaatcc gtgcagttgg tcttaatcca catgcttcag aatatgctgg tatttctgcc
    15781 aagcggacta ttatcctatc tatgattatt tcaggtgcct tggcaggtct tggtggagct
    15841 gttgaaggtt tgggaacctt ccagaacgtc tatgttcaag gttcgtcatt agctatcgga
    15901 tttaacggaa tggcggttag tttgcttgcg gccaactcac caattggtat actctttgca
    15961 gccttcctat ttggcgttct ccaagttggg gctcctggta tgaatgcggc gcaggtacca
    16021 tctgagcttg tcagcattgt aacagcgtct attatcttct ttgtcagtgt tcattacctt
    16081 atcgaacgct ttgtcaaacc gaaaaaacaa gttaaaggag gtaagtaaag atgtctataa
    16141 taaccttgct ccccctcttg gtgtcttcta tgctgattta ctcagcacct ctcatcttta
    16201 caagtatcgg tggtgttttc tctgaacgtg gtggtgtggt aaacgttggc cttgaaggaa
    16261 ttatggttat gggtgccttt tctggagttg tctttaacct tgaatttgca gaacaatttg
    16321 gagcagcaac tccatggcta tccttgcttg tagcaggatt ggttggtagt gttttctcta
    16381 tcatccacgc agcagcgacg gttcatttcc gtgcagacca tgttgtcagc ggtacggtat
    16441 tgaacttgat ggcgcctgcc ttggctgttt tcttagttaa agttctttat aacaaaggac
    16501 aaaccgacaa cctaagtcaa acttttggac gctttgattt cccagtcttg gcaaatatcc
    16561 cagtgattgg tgatatcttc ttcaagtcaa ctagtctact tggttatctg gcgattgcct
    16621 tctcattcct tgcttggttt attctcttta agactcaatt tggtcttcgt ctccgctctg
    16681 tcggtgaaca tcctcaagca gcggatacct tgggaatcaa cgtctacaag atgagatatt
    16741 tagggattat tatttcaggt tttctaggtg gaattggcgg agcgatttat gcgcaatcaa
    16801 tctcagttaa cttctcagtg acaactattg ttggacctgg atttatcgcc cttgctgcga
    16861 tgatctttgg gaaatggaat ccaatcggtg ctatgctttc tagtctcttc tttggacttt
    16921 cacaaagttt ggctgttatc ggttctcaat tgccgttcct acaaggagtg ccagcggttt
    16981 atcttcaaat tgcaccttat gttttgacaa ttcttgtctt agcagccttc tttggaaaag
    17041 cagtcgcacc aaaagcagat ggtatcaact acatcaaatc aaaataagca tacaaaaaaa
    17101 cgtcagtcca atgactgaac tgccccccaa aagttagaca gaaaaaatct aacttttggg
    17161 gtgtttttat tatgaaattg agttgtgatg ataaagttca gatctatgaa cttagaaaac
    17221 aaggatatag cttagagaag ctttcaaata aatttgggat aaacaattct aatcttaggt
    17281 a
//
LOCUS       DAVLTG010000039        16496 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLTG010000039 DAVLTG010000000
VERSION     DAVLTG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.040"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..567
                     /locus_tag="VYN12_001476"
     CDS             <1..567
                     /locus_tag="VYN12_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1415843.1"
                     /translation="LDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQ
                     DSRKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFF
                     GLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(625..3171)
                     /locus_tag="VYN12_001477"
     CDS             complement(625..3171)
                     /locus_tag="VYN12_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1415844.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(3294..3734)
                     /locus_tag="VYN12_001478"
     CDS             complement(3294..3734)
                     /locus_tag="VYN12_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1415845.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLGDLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(3709..4578)
                     /locus_tag="VYN12_001479"
     CDS             complement(3709..4578)
                     /locus_tag="VYN12_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1415846.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(4620..5348)
                     /locus_tag="VYN12_001480"
     CDS             complement(4620..5348)
                     /locus_tag="VYN12_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1415847.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(5356..5835)
                     /locus_tag="VYN12_001481"
     CDS             complement(5356..5835)
                     /locus_tag="VYN12_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1415848.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQYRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(5846..6544)
                     /locus_tag="VYN12_001482"
     CDS             complement(5846..6544)
                     /locus_tag="VYN12_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1415849.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKSLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(6537..6803)
                     /locus_tag="VYN12_001483"
     CDS             complement(6537..6803)
                     /locus_tag="VYN12_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1415850.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(6869..7795)
                     /locus_tag="VYN12_001484"
     CDS             complement(6869..7795)
                     /locus_tag="VYN12_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1415851.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDVLMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(7870..8685)
                     /locus_tag="VYN12_001485"
     CDS             complement(7870..8685)
                     /locus_tag="VYN12_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415852.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFIS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(8689..9009)
                     /locus_tag="VYN12_001486"
     CDS             complement(8689..9009)
                     /locus_tag="VYN12_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1415853.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(9351..9431)
                     /locus_tag="VYN12_001487"
                     /pseudo
     CDS             complement(9351..9431)
                     /locus_tag="VYN12_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9475..11472)
                     /gene="metG"
                     /locus_tag="VYN12_001488"
     CDS             complement(9475..11472)
                     /gene="metG"
                     /locus_tag="VYN12_001488"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1415854.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWALDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(11596..12855)
                     /locus_tag="VYN12_001489"
     CDS             complement(11596..12855)
                     /locus_tag="VYN12_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1415855.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(12857..13558)
                     /locus_tag="VYN12_001490"
     CDS             complement(12857..13558)
                     /locus_tag="VYN12_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1415856.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(13542..14741)
                     /locus_tag="VYN12_001491"
     CDS             complement(13542..14741)
                     /locus_tag="VYN12_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1415857.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PIHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            15006..16352
                     /gene="gor"
                     /locus_tag="VYN12_001492"
     CDS             15006..16352
                     /gene="gor"
                     /locus_tag="VYN12_001492"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1415858.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAASEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
BASE COUNT         4913 a         3715 c         2923 g         4945 t
ORIGIN      
        1 ctagatcgtt tccatattat ccaacatctc agccgtgcca tgagtcgttt tcgtgttcaa
       61 attatgaatc agtttgaacg aaaatctcat gaatacaagg ctatcaagcg ttactggaaa
      121 ctcatccaac aggatagtcg taaactcagc gataaacgtt tttatcgccc tacttttcgc
      181 atgcacttaa caaataaaga aattcttgac aagattttaa gctattcaga agacttgaaa
      241 caccactatc agatctatca actcttactt tttcactttc agaacaaaga ccctgagaaa
      301 tttttcggac tcattgagga caatctgaag caggttcatc ctatttttca gactgtcttt
      361 aaaacctttc taaagaacaa agagaaaatc gtcaacgccc ttcaactacc ctattcaaac
      421 gccaaattgg aagcgaccaa taatctcatc aaacttatca aacgcaatgc ctttggtttt
      481 cgaaactttg aaaacttcaa aaaacggatt tttatcgctc tgaatatcaa aaaagaaagg
      541 acaaaatttg tcctttctcg agcttagctt tttttcaacc cactacagtt gacaaagagc
      601 cttttctttt tattttaggc ttatttatgc atttccgtat tgaagaacaa ctgcttcgac
      661 tgcagctttt tcacggctaa tcaagtcaac acgtgctgca atttccttga ttcccatacc
      721 gatgttacgg ctaagagcaa ggtcagaaag ctgcggctca aagaactcct tgtattccgc
      781 caagcgttgc tgagtcttaa atacatgagc aggaaggata acaaagctat caaagctcat
      841 atctcctcca agggctgcct taatccaagc ccagttttca cgcgcccaag accaagctgt
      901 tttctgagtt gcttgatgag ctaggaattg gtaataccaa gcagacaagt cctgtggttt
      961 gaccacaaat ttgtccttcc aagaagtaat caggttttgg atattatccg catctgtact
     1021 gtatgcaaga gctgctgcca actggcgttt aaagacagca tctgttgcgt gagtataagt
     1081 atcaagataa agtgctaaca agtctttagt ctcatgatgt ttcatctcat taatcagaac
     1141 ttgtgagcga atagctgctg ggagtcctgc aagattctcc ttgtgtgttg cgaagatttg
     1201 gctagcgact tgactagctt ctgcatcatt tgagcgaatc atcatcgaaa cagccagctg
     1261 acgaaccaat tcatcctcat ctgattctcc gtctttagct tcaaaaccaa gacggtcata
     1321 gttatgacga gccaatttag caaccagtcc tttaaaggct gtttcagcat ccgttccttc
     1381 atcaataaag cgctcaaggg ctgaaatcac ttgagaaaca gctgaaacca ccagataaga
     1441 ctcttcctta gcaagtttat caagaactgg aagcaagtct gcataagaaa tgtgccctgc
     1501 ctcagccaac aaacgacgtt cttgaacaat ttgcagtttg cttgtgttat caagtgtctc
     1561 tagctcagca agaacagctt ctaacaagtc tccttgatag tcggtaatat agtgggcagt
     1621 attttcagtg ttgagacgaa gagctccttc attttcagca agaagagctg cgtagccagg
     1681 gatttcgata ctttcagttt cgagtgtatc aggcaagcct ttccagttgc tattgagggg
     1741 caccacccag agacggttct tgtcttcgtt ctcaccgatg aagaattgtt tttgtgaaat
     1801 cttcaagaca tcattttcaa ctttgacagt aagaactggg taaccaggct gttccaacca
     1861 agaatccatg aaggctgcga catcacgtcc tgacgcttga ccaagggcat cccaaaggtc
     1921 actaccaatg gtgttgctgt attggtgttt ttcaaagtag gcatgcaaac ctttagcaaa
     1981 atcagcatct cctagccaac ggcgaagcat gtgcatgaga cggcttcctt tggcatagac
     2041 gatagcgccg tcaaagagtg tattgatttc atctggatgt ttaacttcga cgtggacaga
     2101 ctgaacgcca tcagtagcgt cacgttcaag agcaagaggt actccacctg tttggaaatc
     2161 ttcaaagata ttccagcttg gttcgatggt atccacacag acgtattcca tcatattagc
     2221 gaaactttca ttgagccaaa ggtcatccca ccatttcata gtcacgaggt tcccaaacca
     2281 ttggtgagcc aattcatggg ccacaacaag ggcaacttgt tgacggctag caaatgtaga
     2341 gttctcatcg acaaccaagt aaacttcacg gtaggtcaca agaccccagt tttccatagc
     2401 accagctgag aagtcaggaa gggcgatgtg gagagattga ggaattgggt acttaactcc
     2461 atagtaatct tcgtaaaact cgatagagcg aacagcgata tccagtgaga aatcaagatt
     2521 tgaaagtgga tgtgctttgg ttgagtagac acctaccagg gtaccatttt tagttttagc
     2581 ggtcacccct tgcaaatcac cagcaacaaa ggccaacaag taagaagaca tgcgaggtgt
     2641 tgtctcaaac ttccagatac ctgtttcctt acggttttca acatcgattt ctggcatgtt
     2701 tgacaaggcc aattcacctt ctgcttggtc aaagcgaaga gagaggtcaa aagttgcttt
     2761 ggcttcaggc tcatccacac atgggaaagc ttcgcgcgca aaatggctct cgaactgagt
     2821 agacaagacc tccttcttga ctccatcaac tgtataataa gaagggtaaa tccctgtcat
     2881 gttgtctgta attttaccag aaaaggcaag aaccaattca acttgaccag cctcagccaa
     2941 ttcgatatga agggcttcat tgtcatggtc aactgtaaat ggacgagctt gacctgcaac
     3001 ttctacagag gtgatttcca agtctttttg gtggagggag atgcggtcac tctgtgcttg
     3061 accagtgatg gtcactttcc cagaaaaagt cttggtctca cgactcaaat ctaaaaataa
     3121 atcataatgt tcaggaacaa attgcttaat aaaatgttca actgcttgca tagttttctc
     3181 ctattctaag tttaagagct gctgctcttc ttcaaacaaa cttattatat catattttgc
     3241 ttgagaaaaa aggattggac agcgatttcc aaaactttct tccttctaat agtctacagt
     3301 gggtagacct tgcgaaattc ttctaaaaca accttgcttt caggtgtaaa agtcagccct
     3361 acttcaccca aacagtctgt gaaaaagtcc tcatgaacct ggcgccaata ggcaagtgat
     3421 ttgtctccct caccttcctt aaaggcatgt tgcgcagaaa cttgattgaa gagttcaaca
     3481 gaaacctttg taatttcgac aatgcagaca gcctgatttt gactatctaa aatgacatcg
     3541 aaggtcccta cttggggaag tggttcgtct tctagtacat agaggtcata ggctgatgct
     3601 gttgctgtct tttctccttt aaacaccaaa tcccctaaaa ggtctggttc aactccaaaa
     3661 gcccaagcat cgatttcatc tccgatagaa ggattgattt gcttgtattt attccacatt
     3721 tcttgcggta tcatgggtac tcctttgtaa ttttttactt tcttctttta tgtgtttaag
     3781 atgatctgga tggtcaatct ctaaatcaaa aatctctgga atagaactgt agtggataat
     3841 gcacttgata cccaactgat tcattttttg tatgaaagaa gtattcagat agcctgctac
     3901 agcaaaatta atcttgttct ttcttgcttt atcctgcata tctcttagca tatctaacat
     3961 tattggactt tccatatcat gccattgact gtttctcata gtcgcaaaaa caaaggaagt
     4021 caaatcattc attccaacta caatctttga aatgcccgtt tccagtatac tagataagtc
     4081 aaaatacgct gacggtaatt caatcatcgt tccgactttc ccagtaaagc catactgacg
     4141 caatactgta atagcttgtt ttaattggtc ggcatcattg acaaaaggaa aaataagaga
     4201 cagattggga ttggtttgat aaacttctgt aacgacatgt gcttcagcct gaaattcatc
     4261 caaacacgcc agtaaacgcc tggttcctct atagccaaac aagggatgcc cttcgtcaaa
     4321 aaactctcta gtccccgcta aacaattggc ttctgtattc gttaattcag aaaaacgata
     4381 ccaaacttcc ttatctaagt aaaaggagca aatagtatca agataatctt ttacaaattg
     4441 ctgacaactt gctaatatga tgttttgatt aagctctctc aataagtatt ccccacgaat
     4501 catgccgacg tggtgaaata gttgaggata aattttttca agaatttttt cgccactaag
     4561 ggcaagttga tttctcatag ccattcacct cgtcttaaaa gatacaatat catatataat
     4621 tatatcaaaa tttcctctag ttcaaaagct tcataaggtt cagataactc atatcctaaa
     4681 aattctgcta cttttttgga agcctcatta tgagcatccc aaagtggaaa catatctcta
     4741 tttaaactct ctagaatcat tgcagcacca agctttttag caaatccatt tccttgttcg
     4801 tttggtctag ttgcaacttc cacttcaact gctttacggt aaactaaccc tgaggaaatc
     4861 ccagcaatca gttcattatt tttaagaatc acaaagccaa atccaccttt taaaacaaaa
     4921 tcctgatagg actcaaaatc cccctgtaaa tcctgtgacc attcttccgt agaaaagcag
     4981 ttataaatat gattatcaat aggcacaata ttgtaacctt cctctaaatg agtaactaga
     5041 ttatttaaaa attcaacttg aaaatttgcc ttatctttaa aagaatagcg agtaaaagaa
     5101 tttagcccca cttttcgatg cagaaaatct tgccaattag tattttctga aataataatc
     5161 ttataatcta aaccatattt tctaacaaaa tcttcccaaa atctggaatc caactcccct
     5221 gctaggtata gaaaattccc aacatcataa aagcttgttg tcctatcatt gtttcggtag
     5281 acagttccaa tttgagattt aagaccatag agaaccatat ttttcttcca tgttttaaat
     5341 agttccatta tccctctact tcaccttcca attcatgtaa gaagtcttgt ccagttctgg
     5401 aaatcctaat aattcagact taaccttcaa gactaatggc gatgcatttt cttctgtaat
     5461 ctcttgaata tccatccaaa tatatccaag tgaatcattc gcaccatcag acacagcttc
     5521 cgaagtcgta acttgaggtg cactctcatt catttcaaca tcatacaagg ccatgacatg
     5581 gtgaaccata aaatttttta actcttccct aacgaaaaca tcgtagattc gaggattaga
     5641 gtagcttcta acagtaaatc ccgtctcttc cataacttct ctagtcagcg tttccgtcag
     5701 tccttcacca agttgctgac tgcctccagg tagatcatac cgatattgat aagggcctct
     5761 cgttttttca atgcagagta acttcccatt ttctaagcaa acagcgtaga ctccaaagtg
     5821 ttttttgatt tccatccaac tcctcctact tcaaagacca gccaccatct attgtcaaga
     5881 tttgtccttg catggcgctc gcttttccac ttgctaaaaa aagactaagc tctgctattt
     5941 cctctggctc aatccagcgc ttgattgggg tttcactagc cacccagtca gccaaaccac
     6001 ctggttcaaa atccgcagcg gtcatagctg tcttgactgc tcctggagcg ataccaaaga
     6061 cctgaatccc agcttcagca tagtctagag ccaactgctt ggtgaagcca gccaaggcat
     6121 gcttggatga agtataggcg tgaccacctc cacctgctag gctagaagca atggaacaca
     6181 tattgatgat gattcccttt ttattttcca gcatttgtgt caaataatac cgagtcaact
     6241 ctactggaat aatgtagttg atttcaaaaa tctcttgaat gtcctgcgcc gtttgttcca
     6301 acagtggttt gtaatcatcc aaaactccag cagtattaca caaaacatcc acctgagggc
     6361 accagtcaaa aataggttcc aagtccaagg tcaaatctct ctgtaaaaag tgaaaatcac
     6421 cctctaagag tgacttttca ccttggtcaa ctccataaac ttgatagccc ttctctaaaa
     6481 agaggcgagc ttgagccaat ccgatccctg aactcactcc tgtaatgagt acacgtttag
     6541 tcatgcactt ctacccaatc cgttgccaaa acatcacaaa ctgtcgggct ccacatggaa
     6601 aaaccttctc cttcgccaga aacgttgatt aggaaataag gtgtcatttc aagtgcaagc
     6661 ccattttgct cgatggtatc aaagagttgg acatagtttt ccgcacctcc ccaaccagtt
     6721 cgtacatatt ttctcttagc ctttaaccca ggcaggatct cttcaaatgt catgtttttc
     6781 tcctttaatt ctacattctt catttaatta tagcaaaaaa ccgctttata cggctttttg
     6841 aatgtgagtt attcaaacct gctactactt acggcaaatt attccctgca gcaagataaa
     6901 tttcatacca ttcttttctt gttaagctaa agtttgccgc tcggctaact tctctcaagt
     6961 gcttaggatt tgttgtacct acgactgcct gcatttttgc tggataacgc aatatccaag
     7021 aaatggcaat agttgaagag gttactccat atttaatagc taaacgatca agtacttgat
     7081 ttaaagcttg aaatttctca tttccaacaa aattcccttt aaaatacccg aattgtaaga
     7141 cagaccatgc ttgaatgacc acatcgtgta attggcaata ttcaaaaatg ctgccatctc
     7201 gcatagctgc ttgactatct tccatattaa catgaaaagc tgattcaaat cctggagtaa
     7261 aagccgcact caattgtagc tgattaacag ctaacggctg cttgacatct tttttaagca
     7321 actccatcat cataggattt tgattagaaa ctccaaaatc tcgaacttta ccttgtttat
     7381 aaaggagatt aaaggcttct gctacttggt cagattccat caaaacatct ggtcgatgaa
     7441 ggagcaagct atctagatga tcaatcttca atctttgcaa aataccgtct actgatttta
     7501 taatatagtc cttagaaaaa tcaaaatagg taaattcttc aatgcgaatg ccacatttgg
     7561 actgaatcca catcttttct cttaaatctg gacgattttt taggacaaga cctaacagtt
     7621 cttcacaacg accacgacca taaatatcag ccaagtcgaa ggcattgatt ccaacagaaa
     7681 gtgctgtttc tacaagctct tcaacttctt ttacagattt atcttttatt ctcatcattc
     7741 cgagaacaat ttctgataat tctttgtcat cttgaccaag agttatgtat ctcatcaaat
     7801 ttttctcctt taatttctaa cattcttccc ttcattataa caaaaaaccg ctttgcaacg
     7861 actttttgac tatacttcac tccattttat cttcttaaac ccacggaaca agacaaagat
     7921 tccaataaag aggacagcta aaggaataac ttttgtaagg aaaacatttg aaattcccat
     7981 ccactcataa taacggagca gagaacccac cacaagatgg gcaataatca tactgataaa
     8041 tggacgaaag accgcttctt tccaattcca aataccgata actagcgaaa tcgtaaagat
     8101 agacaaacta tcccagggag ccggaatata aaaggctcct tcttgtatga agcttgccat
     8161 tcctacatat cctaaaacaa ctagaagaac tatagtccca acaacaatgt aagtgccaat
     8221 tttcatttta ggagaatctt ggactaaact tcttcgtaaa attgtggcca caagtccaaa
     8281 tccaatcaga aaaataagaa gttgccctaa aaatgtgagc aaattgactg ttaagagagg
     8341 acctttagaa aaatcactta gtagttgata ataacgtaat accgccagga caagaattgg
     8401 cgtcaaaagg gactctttga tagaactgcg aggtgctccc ttgagaatct ctttcattat
     8461 ttttttagga ttcttaccta gataatcctc tgcactcatg ccatctcgtt ctgcttctga
     8521 gaaatctagc atcatcaaat agatctgctc tctgagatag tcttcatcat agagaaatcc
     8581 agcaagatta aaactttccc acaactcctc aaaatacttt tgattctcct cagaaaactc
     8641 atgtagcaaa gcgcttgttt cttcgtaata cttcattttc ttcatggttt aacccccatt
     8701 cttaatccct tctacttttt gactcaaatc gtcccattgt tgccaaaaga ctgagacacg
     8761 ctcttctcct tctttcatta atgaaaaata cttccgatct ggaccatctg gcgacgggcg
     8821 catgtcgcct cttatccatt gatttttttc taacttttgc aacaaaggat aaatagttcc
     8881 tggaacgata gtatcaaatc cagcctctcg caaagtctga accaactcat aaccataccg
     8941 ctctttttga ccaatcatat ccaagacaca accttcaaga acacctttta atagctgagt
     9001 ttctttcatc acttctccct tctaatctat tttgtaatac ctactagtaa cttcacctat
     9061 agtatattac ttctacacta gtttgtaaag cataatagtt aatactcttc gaaaatctct
     9121 tcaaaccacg tcagcgtcgc cctaccgtat gtatggttac tgacttcgtc agtttcatct
     9181 acaacctcaa aacagtgttt tgagctgact tcgtcagttt catctacaac ctcaaaacag
     9241 tgttttgagc tgacttcgtc agtttcatct acaacctcaa agcagtgctt tgagctgact
     9301 tcgtcagttt catctacaac ctcaaaaaca tgttttgagc tgacttcgtc agttctatct
     9361 acaacctcaa agcagtgctt tgagcaaccc gcggctaact tcctagtttg ctctttgatt
     9421 ttcattgagt ataaataaaa aaacagaact agtctgaact agtcctgtct acttttaccc
     9481 aatcacactt ccatttggta cagctggatc aactgtgaga agggttaatt tgccatcatg
     9541 ttcagctgag agaatcatac cctggctgac atattttttc atcattttac gtggtttgag
     9601 gttagcaacg atttgaactt tcttgccgac caattcttgt tcatttggat agtattttgc
     9661 aattcctgaa agaatctgac gatcttctcc atcaccagca tccaagcgga attgaagcaa
     9721 cttatctgaa ccttctactt tagacacttc tttgacttct gcgacacgga tttcaacctt
     9781 gtcaaagtct tcaaacttga tttcatcctt gtttagtttg agctcaactt cgtccggatt
     9841 ccattctttt tcgactgctg gtttattgcc ttccatttgt tccttgatat aggcgatttc
     9901 ttcttccata tttagacgtg gaaagatagg tgttcctttg gcaactacag tcacatctgc
     9961 tgggaagtca gccaaactca agttttcaag actagaaact tcttccaaac caagttgagt
    10021 caaaactgca cgactagttt ccatcataaa tggttcaatc aagtgagcaa ctacacgaat
    10081 gctggctgcc aagtggctca tgacacttgc caattggtca cgaagagctt catccttgtc
    10141 caaggcccat ggtgcggtct catcgatgta tttattggta cgagagatca gagtccagac
    10201 tgcttcaagc gcacgtggat agtcaactgc ttccatgtgt gtatggaagt ctgcgattga
    10261 ttgttctgca acctcagcaa gaacatgatc aaattcagtc acaccttcta cataggcagg
    10321 gatttgtcca tcaaagtact tattaatcat ggaaaccgta cggttaagga ggttcccaag
    10381 gtcattagcc aattcatagt tgatacggcc gacatagtct tcaggagtaa aggttccgtc
    10441 tgaaccaact ggaaggttac gcatgaggta gtaacgaagt ggatctagtc cataacgctc
    10501 taccaacatt tcagggtaaa cgacattccc ttttgactta gacatttttc cgtctttcat
    10561 gacaaaccaa ccatgggcaa tcaaacgatc aggtaattta acatccaaca tcataagaag
    10621 gattggccag tagatagagt ggaagcgaag gatatctttt cctaccatat ggaagactgt
    10681 tccattccag aacttgtcaa agttaccatg ttcgtcttga gcgtagccaa gagctgtcgc
    10741 atagttaaga agggcatcaa tccaaacgta gacaacgtgt tttggatttg atgggacagg
    10801 cactccccat gtaaaggttg tacgagatac cgccaaatct tccaaacctg gctcgatgaa
    10861 gttgcgtagc atttcattaa ggcgaccctc tggcgtgata aattcaggat gagctttgaa
    10921 aaattcgacc aaacggtctt ggtatttgct aaggcgaagg aagtatgatt cttcagaaac
    10981 ccattcaacc tcatgacctg atggagcaat accaccagtc acatttccag cttcatcacg
    11041 gaaaacttct gccagctggc tttctgtaaa gaattcttcg tctgatactg aataccaacc
    11101 agagtattca cccaagtaga tatcatcttg agcaagtaag cgttcaaaga cttgtgcgac
    11161 aactttttca tggtagtcat cagttgtacg gataaattta tcgtatgaga tatctagtaa
    11221 ttgccagagt tctttaactc caaccgccat tccatcaaca taggcttgag gtgtaatacc
    11281 agcttcttcc gctttctgct ggattttctg accatgttca tcaagacctg tcagataaaa
    11341 tacatcgtag cccatcaggc gtttgtaacg tgctaggaca tcacatgcga tagttgtgta
    11401 ggcagaaccg atatgaagtt tcccagatgg atagtaaatc ggcgttgtaa tataaaaatt
    11461 tttttcagac ataatttttc ctttccaggc aaatgaaacc tgtttttcta acacttcatt
    11521 atatcacatt tttaatgaat ttcgataggg aaatccatac aaaaacaaga tagacgagtg
    11581 tccatcttgt tgatctcatt cataacgaag ggcttcaatt ggatcaagtt tcgatgcctt
    11641 gttggctggc aagactccaa aaatcatacc aacactagcc gaaactgcaa gactaaatag
    11701 ggcaactggg attgatactc caacttctat accttctatt aaaccttgca gtaacaaacc
    11761 tgctaaggca gttaaaccac ttgcaattgt caagccaatt aagccaccta acaaggtcaa
    11821 aatcatggat tcaatcaaaa actgaattaa aatattggca cgtgttgcac ccaaagcctt
    11881 acgaagacca atctcacgag tgcgctctgt caccgaaacc agcatgatgt tcatgacacc
    11941 agttcctcca acaaagagag aaatccctgc gatggaacta ataatcgtcg tcataaaact
    12001 aaacgattgt tgaatttctg caaatacaag ggactcatct gccacctggt attctccctg
    12061 ttgtaagcct gcaagctctg tcatttttcg tgccagttct ggacccagag ttggggttaa
    12121 actggtatca ttcactcgaa agacaatatt agctatttca tctacattaa aattcgcagc
    12181 aagggagata ttggtagtaa taggcaagcc accaaaccca tatatttttg atcttttagc
    12241 ctccggacta gtataaaccc caatgacccg gtaactaaat ccattgactt ctacaacctt
    12301 gttaatagcc tcttgaggag attcaaataa actaatggac aattcctcat ctagcaaaat
    12361 gacacttgca aactctttga aatcttgctc tctcagacta cgacctgcaa taatttcatt
    12421 cttaacagcg tccatgtaag ttctgtttcc acctgtcaaa ttagcattct caaccttttt
    12481 atcttgatag gtcaagatgg cattcgttga attggttaca tagtaactat ccactccctt
    12541 cagtttagct gcctcttgga cccaggattc ttgcggtttt ggcggttcaa caggaacttc
    12601 ctcttccttt ccagaaaccg taaaagctga ttgtttctga gtaaaagacc cgtctttact
    12661 ttttttagga gagaaaaaga cgctaatatt tttctgagat ttagtcatat ctttattgac
    12721 ttgacgagat agggaatcac ccaaagccat aatcacaaca actgatgaaa caccgataat
    12781 aatcccaatc atagtaagca aagaacgcat cttgtgagcc atgatagatg aaaaggcaaa
    12841 tttcagattc tgcatcttag ttttcctcct ttcctaactg agcactgtca gacgaaatga
    12901 ccccatcccg aatgacaatc tgacgtttgg cataggcagc aatctcaggc tcatgcgtta
    12961 ccatgataat ggtttttcct tctttattca aatcaaccaa taattgcata atttggttac
    13021 ctgttttggt atccaaggct cctgtcggtt catccgctag gataatagaa ggattgttta
    13081 ccaaggcacg cgcaatggct acacgttgct tttgaccacc agataattct gaaggtaaat
    13141 ggtgactacg ttctgtcaat tcaaccttgt ctaaatattc ctcagccaac ttgcgacgtt
    13201 ttgaagacga aactcctgcg taaatcaagg gcaattctac attttgcaga gcattgagct
    13261 tcgatagaag aaagaactgc tgaaagacaa aaccgatttg ttggttacgg accttagcta
    13321 gttgtttttc accaagccca gccacttctt gaccttcaag ataatattct ccactggttg
    13381 gtgtatccaa catgccaatc gtattcatca gagtggactt accagaccca gatggtccca
    13441 tgatggctac aaattcaccc tcattcactt ctagattgat atttttgaga acctgcagtt
    13501 cttggtcacc attacggtaa cttctgaaga tattttttag actaattagt tgcttcatca
    13561 gccttcacct cttttccttc ttccaaggaa gatgttggat tactgatgac cttagcaccg
    13621 ttcgttaaac cagaagtgat ttcttgattt tctgcgtcag catttcccaa tgaaacctca
    13681 acttttttag ccttttgttg ttcatccaca atccagacat aatttttact atcatccatt
    13741 actagactgc taacaggaac aagaatagcc ttagttttgc ttttaacctc aatgttgaca
    13801 gaaaaaccct gtttcaaatc accaacctcg cctgtcacat caatagtata agggtattta
    13861 gaacctgtat tattcccggc tgctggacta gctgcttcac cattgttttt aggatagtca
    13921 gaaatatagc ttaatttccc agtccatttt ttatcaggat acactttaga agtaaagctt
    13981 acttcttgac ctacagaaag gttggctaga ttgtactcag ataattctcc cttgacttgt
    14041 aaattttcat tgctgacaat atgaaccata acttggctcg cccctgttgg agatttagaa
    14101 acattgctat tgacttcgac tacagttccc tctagggtac tgagaacagt tgttgcatcc
    14161 aattgacttt gagccttgct taattgcgcc gcagcatctg cacgcgcatc acgggcatca
    14221 cccaattgag cgtcaataga agcaacagaa tttccagcca ctggagttgg gctttgcacc
    14281 gttgcatctt ctcctcctac tggcgctggt aactgtggag ccggagctga agcggcttca
    14341 tttcgtgctt gattgagttc attgatatga cgatctgccc tagctactgc tcgactagct
    14401 gaatcatagg ccgcctgcgc ttctgaacta ctgtacttga ctaaagcctg cccttcgctg
    14461 accttatcgc ccacagaaac aaggatttca tctaaatcac ccttactagc atcaaaataa
    14521 acatattgtt cattttttgc tgttactgtc cctgacaata aaacagagga ggccacgctt
    14581 ccttccttgg caacaacaag atgaataggc tcatctttta gagcagtctg agaaggttgt
    14641 ctaaagagta aaatcccccc agcacccaat acaactacac tcgcagcacc gattgctgca
    14701 tacagttgcc actttttagc tttaccattc tttttcttca taatgaaact ccttttcttt
    14761 tttacaatac tttgctatta taccaaattt ccctccagca aacaatacag ttcaggatta
    14821 aacaatcgtt cggaattttg cttttctatt gtactagata tataatacac tatcttgact
    14881 tatttggcaa gcttttttgc aattttttgt gcgtagcaga tttttgcaat caaatcaaaa
    14941 aaagaataaa atataactat caaaaaagac gctctactat ttaaaagatt acaaaggagt
    15001 tttcaatgag agaatatgat atcattgcta tcggtggagg tagcggagga atcgctacca
    15061 tgaaccgtgc tggtgaacat ggagccaaag cagccgttat tgaggaaaag aaattaggtg
    15121 gaacctgtgt caacgtcggt tgtgttccta aaaaaatcat gtggtacggg gcacaaatcg
    15181 ctgagacttt ccatcaattt ggagaagact acggctttaa gactactgat cttaactttg
    15241 actttgcaac cctacgtcgc aatcgtgaag cctacattga tcgcgctcgt tcttcttatg
    15301 atggtagttt taaacgcaac ggtgtagact tgattgaagg tcatgctgaa tttgtagatt
    15361 ctcatactgt aagcgtaaat ggtgaactga ttcgtgctaa acatatcgtg attgctacag
    15421 gtgcccatcc aagtattcct aatattcctg gtgctgagct aggtggctct tctgatgatg
    15481 tatttgcctg ggaagaactt ccagagtcag ttgccattct aggcgctggt tatatcgccg
    15541 ttgaattagc tggcgtactc cacacttttg gtgtcaagac agatctcttt gttcgccgcg
    15601 atcgtccttt acgtggtttt gattcctaca tcgttgaagg tttggtcaag gaaatggaaa
    15661 gaacaaactt accacttcac actcacaaag tccctgtcaa gttagaaaaa actactgacg
    15721 gcattaccat tcatttcgaa gatggtacta gtcacacagc tagccaagtt atctgggcta
    15781 caggccgccg tccaaacgtt aagggcttgc aacttgaaaa agctggagtg actctgaatg
    15841 aacgtggctt tatccaagta gatgaatacc aaaataccgt cgttgaggga atctatgctc
    15901 taggtgatgt aacgggcgag aaagaactga ctccagttgc aatcaaggcc ggacgtaccc
    15961 tatctgaacg tctctttaac ggaaaaacta ctgcaaaaat ggattactca actattccaa
    16021 ctgttgtctt ttcacaccct gctatcggaa ctgttggttt gacagaagag caagctatta
    16081 aagaatacgg tcaagaccaa atcaaggttt ataaatcaag ctttgcatct atgtactctg
    16141 cttgcactcg caaccgtcaa gaatcccgtt tcaaactcat aacagctgct tcagaagaaa
    16201 aagttgtcgg acttcacgga attggctacg gcgttgatga aatgattcaa ggatttgctg
    16261 ttgctatcaa aatgggagca accaaggctg actttgacgc aactgtagcg attcacccaa
    16321 cttcatctga agaatttgta accatgcgtt aatcgaaaca aaagaagcaa agcaaaaaac
    16381 acttctaaat atcaaaaagc gagtatttcc gtagttggag atactcgttt tcttatgttt
    16441 tattttatag tatgttgaag taagatatgc aaaaatcaat taacaaacca tagcaa
//
LOCUS       DAVLTG010000040        16366 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLTG010000040 DAVLTG010000000
VERSION     DAVLTG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.041"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            68..418
                     /locus_tag="VYN12_001493"
     CDS             68..418
                     /locus_tag="VYN12_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1415859.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREDDTH"
     gene            633..749
                     /locus_tag="VYN12_001494"
     CDS             633..749
                     /locus_tag="VYN12_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1415860.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            742..975
                     /locus_tag="VYN12_001495"
     CDS             742..975
                     /locus_tag="VYN12_001495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415861.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLASEVASQQLGMSVSEFEALL"
     gene            1102..1383
                     /locus_tag="VYN12_001496"
                     /pseudo
     CDS             1102..1383
                     /locus_tag="VYN12_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1517..2485)
                     /locus_tag="VYN12_001497"
     CDS             complement(1517..2485)
                     /locus_tag="VYN12_001497"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1415862.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALSEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2630..3445)
                     /locus_tag="VYN12_001498"
     CDS             complement(2630..3445)
                     /locus_tag="VYN12_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1415863.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(3470..3967)
                     /locus_tag="VYN12_001499"
     CDS             complement(3470..3967)
                     /locus_tag="VYN12_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1415864.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(4040..5401)
                     /gene="radA"
                     /locus_tag="VYN12_001500"
     CDS             complement(4040..5401)
                     /gene="radA"
                     /locus_tag="VYN12_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1415865.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(5415..5930)
                     /locus_tag="VYN12_001501"
     CDS             complement(5415..5930)
                     /locus_tag="VYN12_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1415866.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5932..6375)
                     /locus_tag="VYN12_001502"
     CDS             complement(5932..6375)
                     /locus_tag="VYN12_001502"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1415867.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            6680..6829
                     /locus_tag="VYN12_001503"
     CDS             6680..6829
                     /locus_tag="VYN12_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415868.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            6971..7150
                     /locus_tag="VYN12_001504"
     CDS             6971..7150
                     /locus_tag="VYN12_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415869.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(7370..7735)
                     /locus_tag="VYN12_001505"
                     /pseudo
     CDS             complement(7370..7735)
                     /locus_tag="VYN12_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            7755..7922
                     /locus_tag="VYN12_001506"
     CDS             7755..7922
                     /locus_tag="VYN12_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV1415870.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(8077..8280)
                     /locus_tag="VYN12_001507"
     CDS             complement(8077..8280)
                     /locus_tag="VYN12_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415871.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(8303..8494)
                     /locus_tag="VYN12_001508"
     CDS             complement(8303..8494)
                     /locus_tag="VYN12_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1415872.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            9066..9434
                     /locus_tag="VYN12_001509"
     CDS             9066..9434
                     /locus_tag="VYN12_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415873.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            9434..9667
                     /locus_tag="VYN12_001510"
     CDS             9434..9667
                     /locus_tag="VYN12_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415874.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            9667..9930
                     /locus_tag="VYN12_001511"
     CDS             9667..9930
                     /locus_tag="VYN12_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1415875.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            9943..10323
                     /locus_tag="VYN12_001512"
     CDS             9943..10323
                     /locus_tag="VYN12_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1415876.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            10340..11410
                     /locus_tag="VYN12_001513"
     CDS             10340..11410
                     /locus_tag="VYN12_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV1415877.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            11465..12606
                     /locus_tag="VYN12_001514"
                     /pseudo
     CDS             11465..12606
                     /locus_tag="VYN12_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(12689..12782)
                     /gene="ffs"
                     /locus_tag="VYN12_001515"
     ncRNA           complement(12689..12782)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYN12_001515"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(12815..13282)
                     /locus_tag="VYN12_001516"
     CDS             complement(12815..13282)
                     /locus_tag="VYN12_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1415878.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(13483..14769)
                     /locus_tag="VYN12_001517"
     CDS             complement(13483..14769)
                     /locus_tag="VYN12_001517"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1415879.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(15000..15236)
                     /locus_tag="VYN12_001518"
     CDS             complement(15000..15236)
                     /locus_tag="VYN12_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1415880.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            15502..16299
                     /locus_tag="VYN12_001519"
                     /pseudo
     CDS             15502..16299
                     /locus_tag="VYN12_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5461 a         3592 c         2748 g         4565 t
ORIGIN      
        1 aatttgactt tcctgataga gttattcaca tcttatttca actcactata gaaggaggaa
       61 taggaggatt ctcagacatc cgggcatcag cccaactaat gatttgattg ctaagaaaat
      121 attcagcaat ccagaaatca cttgtcaatt tattcgcgat atgctggact tgccagcaaa
      181 aaatgtgacc attttggagg gaagcgatat tcacgtatta ctctccatgc cttactcggt
      241 gcaggatttt tataccagta tagacgtctt ggcggagttg gataacggta ctcaagtaat
      301 tattgagatt caagtccatc atcagaattt tttcatcaat cacttgtggg cttacctgtg
      361 cagtcaggtt aatcaaaatc ttgaaaaaat tcgtcagcga gaagatgata ctcactagat
      421 ctacaaacac atcgctcctg tttacgtcat tgctatcgtg gatagtaatt atttctcaga
      481 tgacctggct tttcatagct ttagtatgcg cgaagacaca acaggtgagg tattggcgat
      541 taccaacaat ggacaggaaa accatctggt taagatggca ttcttggaat taaaaaatac
      601 agagaaacca gcaaagacaa ggttcgcaag ccatggttgg agtttttcgg caacaagccc
      661 tttacccagc aaccgcaacg agccattacc caagcaaatc aactgctgga ctacaagagc
      721 tggtccgagg aggacaggaa aatgtttagt caactacata tgcgagaaga acaagtcttg
      781 ttagcacagg actatgcctt ggaaactgct agggctgaag gccttgaaca aggactagag
      841 cgtgggaaag ttgaaggaag ggcagaaagg aaactttttg ccttcctaga catagtacgc
      901 caaggtcttc tggcttctga ggttgccagc cagcaattag gtatgtcagt atctgaattt
      961 gaggcactgt tgtaaaatgg ctccataata tccatagggg atttacccac tatggatatt
     1021 atggagccta ttttgtgtaa aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa
     1081 caactcatta gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt
     1141 aaagacccta atgtccagat tttaaacatc atcaataagg atacacacaa ggaaatcatc
     1201 gccaaactgg actacgacgc cccatcttgc cctgagtgcg gaaaccaatt gaagaaatat
     1261 gactttcaaa aaccttctaa aattccttat cttgaaacga ctggtatacc tactagaatt
     1321 ctccttagaa agcgtcgatt caagtgctat cactgttcaa aaatgatggt cgctgaaact
     1381 tctgatgacg tacagtcata tttcttctct ttttattata tcacagtttt aaatctagct
     1441 ttactagatt caccgctact atctatttat tcggaaaaaa gacgaaaaaa cctgagaatc
     1501 atctcaggct tggtcattaa atttttttct caatatcgaa aagtggagaa agtggtcgtt
     1561 tttcatgaat acgtacgata gcatccccta ggagatgagc gattgaaatc tgctcaatct
     1621 tatcaatcaa acgctcttct ggcagataga tggtatccaa aacaaccaat ttcttaatag
     1681 ctgatttttg gatattgtcc gtagcaggac cagaaagaac tgggtgcgta cagcttgcat
     1741 agacttcaac agcaccagct tccgaaagag catctgccgc atgacaaatc gttccagcgg
     1801 tatcaatcat atcatcaatc aagatacaag tcttgccttc aaccttaccg atgatgttca
     1861 taacttcact agtattcatc ttatcaacgc tacgacgttt atcaataata gcgatagatg
     1921 ttttcaaaaa ttctgccaac ttacgagcac gagtcacccc tccatggtcc gggctgacaa
     1981 ccacatagtc agaaccaacc ataccacgac gctcaaaata atctgcaatc agaggagcac
     2041 ccatcaaatg atccacagga atatcaaaga atccttgaat ttgcgcagca tgcaagtcga
     2101 tggtcaataa acgatccact ccagctactt caagcatatt tgcgacaagt tttgaagtga
     2161 ttggctcacg cgctctcgcc tttctatcct gacgtgcata cccatagtaa ggcatgacaa
     2221 cattgacaga ttctgcactc gcacgcttca aagcatctac cataatcaaa atttcaagca
     2281 gattgtcatt tacaggcgaa ctagttgatt gtaggataaa gacgtgtttc ccacggattg
     2341 attcttcaat gttgacctga atctctccat ctgaaaattg gcgaacactt gatttcccca
     2401 actctatccc aatctcctgc gctacacgtt ctgccaattc tttattagaa gaaagggcaa
     2461 acagctttaa atcagaaaaa gacatgattt cctccggtat atatgtataa cttgtgcttt
     2521 tcacaagatt ttccatctac cattgtagcg ctttttgcac tatttttcaa tcaaaaataa
     2581 aagaagggca ccatatttgt acccttgcat cattcttttg aaaaatattc taggtcatca
     2641 actcattgtg tttctcaaca aagcaataag catgataaaa accatagaga gcaatagccg
     2701 taaccactgg aatcgctaaa ggcaactctg tttccaactc cacaaaagga gagttaaaca
     2761 agaagtgagt tcccaaggct aaacctagaa aaataaggcc ctgtttcttg ccaaccttct
     2821 gtcctttata ggctctgtaa agcaagtaaa cacctactac agctagacct gaaaaagtcc
     2881 agtgagaggc aattcctgag atgatacgct ctaaaattcg cgaaatagta aagtcaaagc
     2941 cctctggcaa atccgtacga atataaccaa tatcctcaat catttggaat cccaaaccgg
     3001 aagcaattcc aagtaaaaac aaagatttta attttcgcac aggaatcaaa gccaaaacaa
     3061 aaacaagtgg caataatttc aagggttctt ctaccaaagg agccacaata gcactttcaa
     3121 aggcatttaa aaatgtacta tctgggaaaa gaacccccag taaatcatgt atataagtat
     3181 tagcaaaact agacaaccag cctgaaagga acatccctcc caataaagac agaatcaaaa
     3241 ccttctttgg caattcccat tttttcccaa tacggaagag aaaataaaga gccggaatca
     3301 tgtaaaagag agctagaaag atagaaactc ccattagtcc atattccgca cctgacctcg
     3361 aaccgtccgt atagtagatg gtttcatact gtaaaccaat acatagcaat aaaataaaaa
     3421 taaataaaat actgcttttc ttcatacact ttctttctaa atgaagtatt tataattcta
     3481 cgactgtcat acttcctgta tcaacattgt aaatagcacc agagataatg acatcgtctg
     3541 gtattagggg agactcgata agcagttgca tatcctcgcg tacactctct tctatatctt
     3601 ggaagggcaa gaagtcctgg tctgacacat ctacacctaa ttcctctttt aaatactcct
     3661 gaaaaggttc attttcaaag gtctgagcac cacagtctgt atggtgcaat accacaatct
     3721 ctcttgtccc catttgttgc tgggaaataa ctagcgaacg aatcatgtct tcagtcactc
     3781 gaccacctgc attccgcaag atatgagcat ccccaagtgc caagcccaga gcttgcgcaa
     3841 cgtgcaaacg tgagtccata caggtcacaa tggctactct ggttttaggt ttaagtggca
     3901 gatttaactg cccatgtagg gcaacataag cctgattggc ttgcataaac tgttcaaaat
     3961 acgacacgat tccctccttg aaaatttgat agtcaaatat ttctcctatc ttatcatttt
     4021 taagagaatt tgtcacggat tatgcaaaga cctttttcaa gacttcctga atcgttgtca
     4081 cgccaatgac ctgaatttcc ttaggcagag tgattcctgt caaggaattc tgaggtacat
     4141 aaatcttagt aaagcccagt ttagcagctt cgttgatgcg ttgctcaata cgattcacgc
     4201 gccgaatctc tcctgtcaag cccagttctc cgacaaaaca ttcctgagga ttagttggct
     4261 tgtctttgta gctcgaagca atagcaactg caacagccaa gtcaatggca ggttcatcca
     4321 atttaacacc accagcagat ttgagatagg catcctgatt ttgcaagaga agccctgccc
     4381 gtttttccaa aacagccata atcaagctag cacggttaaa atcaagtcct gtcgtagtac
     4441 gcttggcatt tccaaacatg gtcggtgtta ccaaagcctg aacctccgcc aaaatcggac
     4501 gcgtcccttc catggttaca acgatggagg aaccagtcgc cccatccaaa cgctcttcta
     4561 ggaaaacttg actcggattg agtacctcaa ccaagccgcc cgactgcatc tcaaaaatcc
     4621 caatctcatt agtggaacca aaacgatttt tgaccgctct caaaatacga aaggtgtggt
     4681 gacgctcccc ttcaaagtaa agcaccgtat ccaccatatg ctccaacata cgaggcccag
     4741 ccaaggttcc ttctttggtc acatgaccta cgataaagat ggcaatgtta ttggtcttgg
     4801 ccaactgcat gagttcagcg gtcacttcac gtacctgaga aacagacccc tgcacccctg
     4861 aaatctcagg agacatgatg gtctggatgg aatcaataat gagaaagtct ggctggatac
     4921 gctccacttc tgcacgaaca ctctgcatat tggtctctgc atagagataa aactcactat
     4981 caatatcacc taagcgctct gcacgtagtt taatctgctg ggcagactcc tccccactga
     5041 catagagaac tgtccccact tgggacaact gggttgagac ttgtaggaga agagttgatt
     5101 tcccaatccc aggatcccca ccgatgagga cgagacttcc tggtaccact ccgcctccaa
     5161 gcacacggtt gaattcctcc atctccgtct tggttcgatt gacattgatg gaagtcacct
     5221 cagctagttt catgggcttg gttttctcac ctgtcaagga cacacgcgca ttcttgacct
     5281 cggcaacctc aacctcttcc acaaaagaag accaagaccc acagttgggg caacgtccca
     5341 gatatttagg ggaattatac ccacaatttt gacatacaaa tgtcgctttt ttctttgcga
     5401 tgacaaacct ctttctatat ctctaactca cactcaatca cttggcaaaa atcaatcttc
     5461 tcatttggca caaactggcg catgagcatt cgatgagcaa caactaccac agtctgatgt
     5521 tctcgatact tagacataca ttctagaaac cgagacttca tttccgtagc tgtctcatat
     5581 tgaataggac tattaggaag caactccccc ttgttttcta aaaacagtct tctagctgtt
     5641 tcaaagtttt ctattcctgt tttatagacc tgccattcat gtaataaagg ctctactctt
     5701 aaaggaagac ccgtagcaca gaccacatac gaagccgttt ctaaagctct tgtgactgca
     5761 gaagatacga ttatttcagc tgacgagagt aaaggatttt tgctcaattt ctggacttgc
     5821 tgccgtccca tctcagacaa gggtgccaaa tctatcccaa atcctatata agaacgctcc
     5881 tctaactcac ggtaatctgg ctccccatga cgtacaaaga taatcttcat tctagtgccc
     5941 tgtcgatcca aatccaccag ttcgaacgcc atcagctgca tctccatctg caattaagaa
     6001 agtagcaaaa acagcctgga caatacgttc cccaacttca agaacaacct cttgatctgt
     6061 gatattcttc atctgcgcaa aaatatgccc ttcatttcca ggatttccat aataatcccc
     6121 atcaatgacc ccaactgagt taattaaaac caagcccttc ttacgaggat ttgaagaacg
     6181 atcatagagg tagagaacct cagtcggctg catataagcc ttaacccctg tcggaaccaa
     6241 gacaatctct cctggcgcaa caactgtacg cacagcaacc tttaagtcgt aaccagccgc
     6301 atgcgctgtc tcacgcttgg gcaataaatt ttcatctgta aaactcgaaa ccaattcaaa
     6361 accacgaatt ttcataattt tctcttttct attatcattt attctagatt attctatctt
     6421 atttattcgg aaaaagcacg aaaaaaagag cacacaacaa ttataggcga tacgataatt
     6481 tacactgttt cacaatacgt tgaaatttag agctttaaag cgagggcaaa gttgattttt
     6541 tacatcgttt tacagaggtt tacgacactt ttgccccttt tttgcccctt tgtttttcaa
     6601 aaaaacttca tcaaatcgct tgactttcac gatttaccgt gatataatat aatcaagata
     6661 aggaaaggag gtgaggaagt tgaacaaaga agattggctt aggttactgg aaaaggcgat
     6721 agataatatc cctgaaacgg taactgctat agcaagtctg gtgactgcaa taacggtcgc
     6781 aaggcaaaac aaaaagcgta aaccgaaatc ccgtcaaaga aaaaggtgaa cgctaagagg
     6841 ttggggcgaa agcccctcac acctctattt tatcaaatga aaagaggaaa agcaatggtt
     6901 agtgcaatag ctatttttat aattgcggtc aatgtatata tttatctaaa aaataaaaag
     6961 gacaaataag atgagagaag ttattcaaga attgttagac agttcgatgt ctacatctgc
     7021 tatttcccaa ggtgctggag ttccatggac tactgtttct gacctcagaa aaggaaaaac
     7081 aagcatggac aaaatggcac ttctcacagc agaaaaactt tatgaatttg ctacaactga
     7141 taagcagtga tttcggtcac tgtttttatt tttgacaaaa caccgttttt gacaataatc
     7201 aaaaaataaa aaggagctat tattaacaaa atggcgtttt tggcaataat accctgccat
     7261 tcctcctccc tattcttcaa gaaaacgctt ttttgaagaa tcagagcaaa taaaaaaccg
     7321 caagcctgag cctgcggtga aagaacaatt tagaaagttt cctttctatt tatttaactg
     7381 taatcaagcc atctggctct actgtgaact ctggcttgtc tgccagtgtt ccgtctggtt
     7441 tgaggtagta ccagcctgtt ccgtccgctg actggataaa ggcatttgat accatggcgc
     7501 cttctttagc gtctaagtag taccaagtgt ccttgtactt gacccagcct gtcttcatgg
     7561 caccttctac atcaaaatag taccacttgt cagcgatttt cttccagcct gtggccattt
     7621 cgcctgattg gtcaaagtag taccaattac cgtctgtgtg cttcttccag cggtctgaaa
     7681 gcatatagcc tgagccatcg aaataatacc agataccgtt gattttctca aacttataga
     7741 aaggaggaga tagtatggca aatactccaa taaaacctgg aacagataat cagaaacctg
     7801 gtcgctatgt agaggtagga cctcgtggcg gaaaagttac taatggtcat accgcaacta
     7861 tcggaaaagg tgatcggctc cctccgacat ctgctaaagg caacggttgg aaaaaagtct
     7921 aatcttcgtt tgcgtacaat cgttcaatgg ttgtacgctt tttccataca caaaagcaca
     7981 ttcccaaaaa atcaatttga atccatgctt cggcgtaatc tttcccattg ctggcatagt
     8041 gagttatata atggtgaatc attttattcc ttcctcctat tgagttactt gagaagtatc
     8101 atgaatggct tcatagctaa gacgcttaaa ttcttctgag tctatctgaa aattgatagg
     8161 ctttttttgt aaacactcaa gaaaactagt gtttcttaaa agtttttcaa ctaactcagg
     8221 gtctgccttt acaaaggtgg actctttttg tccactatac ggatatcgtt ttggtctcat
     8281 tttcctactc ctcaaatctt tcctactcaa tcccataatc ttcaataacc tgaagaatga
     8341 aactgttcgc tcgtggacct ttagtcgttc cacttagaat gtttgtcact tcctgtcgtt
     8401 taaagccgta agcaaccgct agagttgctt ttttaatgcc tttctctttc aagaaagcaa
     8461 taactctttc gcgaccgttt gcgatatctg gcatattttc tcctttcttt ttctttcttc
     8521 tttttctgct ataatataag cagaaaggag ttaaccttat gacttttaaa gaatatttac
     8581 tcaaagcaag caaacgcgac atctacgatg atggtaaaga ttttgagaaa tcaatttcag
     8641 attctcacta atcgagcgtg acttttttga tatggcaatc tcagaaattt accaccagcg
     8701 ctgactacct taatgacttt ttcaaggtgg tctttttctt gttctaaatt tttaagaata
     8761 cttaccatca gcacgttcct cctctttact tatttgtaaa taagaaacaa ctaaaaatgt
     8821 aactattttt ctgcattata cttgacaact tacaccaaat cggctaaaat taaagcataa
     8881 taaaaacacc aataaatcta taaataccgt tcgccaaaac atttttataa tttatttctt
     8941 agttgttttt ttagttgttt atcacttaca aaaaacattt tacacctttt gggataatta
     9001 gtcaaccttt ttacaccaaa tttgttaaat tttttttgtg atgtcttaga aaggttgatt
     9061 taacaatgtt tgagacattt gaaaaaataa aagaattggc aaaaaagcgt ggaaaagctc
     9121 ttggacaagt agaagaagac ttaggttatg gtagaaatac actctataag ataaaaaatt
     9181 ctacgccaaa cgctgaacgt atcgcagaaa ttgctaatta tttcaacgta tccaccgact
     9241 acctgctcgg acgaacagat aaccctgcta tcgctgggag tgatgaattt gcccaagtaa
     9301 acggacaaat catagactta cgcaaagcag cagccaacac catgttattt gacgggaaac
     9361 cactaaatga agatgatatc gacttcatta catccgtcct atccgcccac ttcaaaagca
     9421 aaggagaacg ctaatgacta tcactatcaa cttcacagaa aaaaattcct acattacgga
     9481 ctacctaaac aaacacggta tcgacacaac gaccatggat tttgacgact tcatggcact
     9541 catggaagat atcgaagacg cacgagcagc cgaccaagcc tatatggagt atttagccga
     9601 cccagctact tataccatgg atgaggtctt ggatgaacta ggactaactc gagaggatat
     9661 tgcttaatgt atcggctaga tattgataaa aaagctctca agcaacttaa aaaactagat
     9721 accccaacca gaaaacaaat cctatcctgg cttgctaaaa acattgaaaa cacgaccaat
     9781 ccacgacaac acggaaaagc actaaaagcc aaccttgcag gttactggcg atacagagta
     9841 gagaattacc gcatcatctg tgatatccaa gacgataaac tagtcgtcct agccgtggaa
     9901 atcgcccacc gcagagatgt ctataaataa cgaaggagaa ctatgacact cgctaaactc
     9961 tgcgaagaat atcaagtaga actttgtctc ttcgacggtt caaactggca caatagcggt
    10021 ttctacaatc cagacacaaa cgtgctcgct attgaccaca acttgactcc tgaacaacaa
    10081 atccaagtcg ccctacacga acttggacac aaagaccaca cacgctcaga gcaccagaac
    10141 gcccgtctac gctgtgaaaa cgaagctgat aggaatatga tccatcatct cgtaaaagac
    10201 gctctagaaa acttagacga ccccacagag tttgattacc tcaaattcat gtcttactac
    10261 aatctaaaaa ccatgacaaa tgaaatcatg gttaaagaag agtatttagc attagtaaat
    10321 taaaaaaagg agtatcaata tggaaattga taaagtaaaa gccgatttaa aacaagtcgg
    10381 caaacgtgta gcagacctca gccaaagcat tacgaatgaa gaacaaacaa agaatgcctt
    10441 cattatgccg ttcttccaag cgcttggata tgatatcttc aatccacttg aatttgtccc
    10501 ggaatttact gccgacgtgg gcattaaaaa aggcgaaaaa gtcgactatg cgatcatttt
    10561 ggatggcgag cctcaaatcc taattgaatg taaatcaatt acagaaaacc ttactaagca
    10621 cgactctcaa ctattcagat atttcgtaac tactaaatca aaattcggta tcttgacaaa
    10681 tggtagagaa tataaattct ttactgattt agatgagcca aataaaatgg acacaactcc
    10741 attcttaaca atcgatgtga ctgatatcaa agaaaatcaa tttactgaaa tcatcaaatt
    10801 ccacaaagag aattttgata ttgataatat tgtttcatca gcttctgaat tgaaatacct
    10861 caacaatctt aaagcgttcc ttactgaaaa tatcactaca ccgtcagata gcttcctcag
    10921 atatctaact tctgaaatct atgaagggcg tgttactcaa aatatcttaa cgacattttc
    10981 tcccattatt gtgaaagggt ttaatcaatt catcacagag cgagttaatg aaaaattaag
    11041 tgctgcactt aatacaagcg ttgaaaccaa agtaacaacc gatattccaa aagttgaagc
    11101 tgaagctgaa gagattgtcg aagtaactga cgaaattatc acaactcctg ctgaattaga
    11161 agtttatact gttgttaaaa tgcttgctag ggatgtagtt tctccagaac gtgtatttta
    11221 cagagataac cgtagctatt tcaatgtttt ggttgacgat aacatcaaaa aatgggtatt
    11281 acgttatcgt tcaaattcaa aaaaaagcac tatcgaaatc cgtgataaag gcatcttccc
    11341 ggtgtctacc cctctcgaag tcgcaaatta tgccaatgaa attttagaag taatcaagaa
    11401 attctcataa taaaaaaagc cctctttact atacccattt tatcaaaaaa gtgaggtaaa
    11461 atcaatgtgg atggaagaat tgccaaacgg caaatataaa ttttttgaga gatacaaaga
    11521 tccatatact gagaaattaa aaaaagtctc agtaacgatg gagaaaaaaa ctccccaagc
    11581 aagaaatcaa gctgcgattt tacttcagga aaagataaaa caaaagttag gagaaaaaca
    11641 acattctgtt tctaatataa cttttgaaaa actatatgaa gaatttgagg agaattggaa
    11701 acacggcgta aaaaactcaa ccgtctacgc ttcaaagaat gtaaaaaaag agattttaaa
    11761 gcagatagag ggcgactacc tagttagaaa tttgatagac gtttattaca aaaagtaata
    11821 gatcaactat tacaagatgg gagatctcat aactatgttt ctaaaatcaa attcaagctc
    11881 aatcagataa tgaaatttgc tatcagaatg aattatattg atacaaatga aatgctattt
    11941 gttgaaacgc ctagaaaagt aattacatcc gacgaactca gaaagaaaaa tacaaaatac
    12001 ttagaccaaa aagagtttaa gttattcatc caaaatttaa aagacgaggc cctatgtgat
    12061 tatcgaatta caaagtatat ccgaatagct aaagttcttt ttcttactgg catgaggtat
    12121 ggagagctgg cagccttaaa ctacaaggaa gatatagatt tttctaaaaa gactattcac
    12181 atcaagcata catacgattt cagacaaaaa gagagaacta caccaaagac aatcaagtcc
    12241 gatagggtta taacagcacc tcaaaaagtg ttagatatta tcaaagagca aataatagag
    12301 aatgcgacaa atggatttga tacagatttt attttcatca atactctagg agaaccaata
    12361 acaaatgcca gggttatttg tgcattgaaa agacatggtc aaaaaatcgg catagaaaaa
    12421 aacataacta cacatacatt tagacattct cacatatccc tacttgctga gctgggcatt
    12481 cccttgactg ccatcatgga cagagtaggg catagtgact caaagaccac actagagatt
    12541 tattctcacg ttactcaaaa aatggtatca gacatatcta gcaagttaga caagataaaa
    12601 ttttaaattg tgcccctcgt ctgccccttt ttcttataca agacaaacaa aaacccctta
    12661 aagtgttgat tttaaagggt ttttaaagtg cacgaaaaaa gagcacacaa ttcaaatcgc
    12721 ttagggctgc tggattcctc ccctgacccg cttcacgcag aactgttgct ccactattta
    12781 ttatatcaca ttcctattca ttttaaaagc aaaattattt tttccgtcta tttctaaaaa
    12841 aatcctgcat gatagctgcg cattcatctt ccaaaattcc tatttcaacc tccacacgat
    12901 gattgagacg ctcatctgtc aagatatcgt acaaactccc agcagcgcca aatttctggt
    12961 ttttagcccc atagaccaca tttggaatgc gggcaagccc aatcgcccca ctacacatga
    13021 cacaaggttc aatggtcaca aaaagtgtgc aatccagcaa gcgccagctc tcctcactca
    13081 agttcgcatc ctctatagcc ataatttccg catgcataac cgctcgctgt aattcctcac
    13141 gcgcattatg cccacgacca atgatttccc catctttgac aatcacacaa ccaattggaa
    13201 tttcatcgtg ttcaagagca atctcagcct ctctcaaagc ctccctcata aagacttctt
    13261 tttcttcaag cgtataatac atctcttttc tcttttccta cttatcgatt ttattattat
    13321 atcatgaatc ccaacacaaa agaagccacc gaatgcggtg actctatagg gagattatta
    13381 tgaaaaagaa aagtttagga tatttgttac aacaagttag gaggtcttct tgtaactgtc
    13441 tatagtatac ccgacctatc ttaaacaaat cttaaaaatc tcttaggacc aaacactttc
    13501 taaaatattt gtttgttcac gaccaggacc tactgagaaa gtagaaatac gaacgccaac
    13561 caattcactc acacgacgaa catagttacg cgcattctca ggaagatctt ccaaattgcg
    13621 aactccggta atatcttctg accaacctgg caactcttca tagataggct tgcaacgttt
    13681 caattgctca agactagctg gatagtagtc aatacgttga ccgtcaagat cataggccac
    13741 acagattttc acagtatcca aaccgctcaa aacatcaata gagttcaaag aaaggttagt
    13801 aataccagaa acacgacggc tatgacgcat cacaactgag tcaaaccaac ctacacgacg
    13861 tggacgacca gttgttgtac catactcatg acccacttca cggatacgtt ctcccacttc
    13921 atcaaacaac tcagttggga aaggaccatc tcctacacga ctcgtataag ctttacatac
    13981 acctacaacc ttgtcaatct tgcttggacc gacaccagaa ccaattgtca caccaccagc
    14041 tacagggttt gatgacgtaa caaatggata agtaccttgg tcgatatcta gcataacacc
    14101 ttgtgcacct tcaaaaagca cacgtttgcc attatcaagc gcatcattca agataacaga
    14161 tgtatctatc acgtatttct tgatttgttg accatattcg taatattctt caaaaatatc
    14221 atcgaaaaca atcgctttac tgtcatacaa tttttcaaaa agacgattct tttcagcaag
    14281 gttacgttct aaacgctcac ggaaaatatc tttatctaaa agatctgcaa tacgaattcc
    14341 aacacgagca gccttgtcca tataagctgg accaattccc ttaattgtcg taccaatctt
    14401 attgtcgccc ttagcttctt cttgcaagcg atccaactcg atatgataag gcaaaataac
    14461 atgcgcacga tcagaaatac gcaagttatc agttgttaca ccttcctcat gaagatagct
    14521 caactctttt acaagagatt taggatttac aaccatacca ttcccaatga cagatatttt
    14581 ttcagggaag aaaatcccag atggaatcaa gtgcaactta aatttcttac cgtcaatcac
    14641 aatcgtgtga ccagcattat caccaccttg gtaacgtgca atcacttctg cattcgctga
    14701 aaggaagtct gtaatcttcc ctttaccttc atcaccccat tgggtaccta caacaacaac
    14761 tgaagtcata attttgtctg agccctcagg ctcttccttt ctcacataca tggcaggact
    14821 ctcacctgca attatatctt acaatttatt ataataaaaa atcgcctttt tatcaagaag
    14881 aaacaataga aagatttgct atttccaact attaaaaaat gatttagaaa aattactagc
    14941 tatttactat tatctttaca taaaagagta aattagttcg gaaatttact aaaattacct
    15001 caacaagaaa taaaaccccg attcattacc aatttttcaa gatacaaacg ataagcaaca
    15061 cgataatggt aaacgataaa atccctatga caaccaatgc catatctcac taaataataa
    15121 attaaaaatt taaaatgaac atgttcccag tcaaaattat caccaaatgt aggaccatac
    15181 tcttcttcaa tactatcata gaaattagcc atctgctcat aaattttttg taacataatc
    15241 aaatactcct tttctttttt ataaacttat tctaacaaaa aattttacac attcactatc
    15301 aattcctgaa ttgttaaaat accagcctca acaagataaa aataggaaaa gttgacaaaa
    15361 tagaaacaaa tttgctacct aaatttcaaa caattaaagt tctaaaaaga ccgccttaaa
    15421 acttttgggt aaatcctatt agaactataa tatttttata taggtattat ggttctgatt
    15481 ttctagtata aaaaaattca aactagaatt cttcttagaa aaggccgttt taagtgctat
    15541 cattgctcaa aaatggagct cgctgagact tctatcgtca agaagaatca tcaaattcct
    15601 tgtatcatca accaaaagat tgctcaaaag ttaattgaaa agatttctat gaccgacatt
    15661 gatcatcagt tgtctatttc aacttcaact gtcattcgca agatcaataa ttttcacttt
    15721 gagcatgatt tttcgcgtct tcctgagatt atgtcctagg acgttgaaac agtccgggga
    15781 gtgactgttt caatcgggag atggagatga gctttattgc tcaggacttt gataaactca
    15841 atatcataac tgttcttgag agcagaacac aagccatcat ccgaaatccc atgaatacaa
    15901 ggctatcaag cgctactgga agctcattca acaagatagt cagaaactga gtgataaacg
    15961 attttatcgc cctacttttc gtatgcactt gactaataaa gaaattctag ataaactttt
    16021 gagctattcc gaagacttga aacaccacta taatctctat cagctcttgc ttttccacct
    16081 ctgtttcaga ctttgtttaa aaccttcctc aaagataaag agaaaatcgt caacgccctt
    16141 caattacctt attccaacgc caaactggaa gccaccaata atctcatcaa acttatcaag
    16201 cacaatgcct ttggttttag gaactttgaa aacttcaaaa aagaaaggac gaaatttgtc
    16261 ctttctagat cttcgctttc ttcaacccac tacagttgac aaagaaccga aaaatgtctc
    16321 gcctctaata tagtcaattg aaacaagaac aagagaaaag agcctc
//
LOCUS       DAVLTG010000041        15654 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLTG010000041 DAVLTG010000000
VERSION     DAVLTG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.042"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            100..450
                     /gene="tnpB"
                     /locus_tag="VYN12_001520"
                     /pseudo
     CDS             100..450
                     /gene="tnpB"
                     /locus_tag="VYN12_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            620..814
                     /locus_tag="VYN12_001521"
     CDS             620..814
                     /locus_tag="VYN12_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415881.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            798..1184
                     /locus_tag="VYN12_001522"
     CDS             798..1184
                     /locus_tag="VYN12_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEV1415882.1"
                     /translation="MTYPVEREEITYKRKKAKGKRQAILAQFDSEEVHHRLENCICPD
                     CQGELKEIGASLQRQELVFILAQLKRVNHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL
                     AHSLGSASIIAHTIHQKFILKVPNYR"
     gene            1203..1514
                     /locus_tag="VYN12_001523"
     CDS             1203..1514
                     /locus_tag="VYN12_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415883.1"
                     /translation="MGLPITRKEIANWHIKASQYYLESLYNLLREKLLEQALLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLR
                     Q"
     gene            1590..2131
                     /locus_tag="VYN12_001524"
                     /pseudo
     CDS             1590..2131
                     /locus_tag="VYN12_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2732..4459)
                     /gene="ezrA"
                     /locus_tag="VYN12_001525"
     CDS             complement(2732..4459)
                     /gene="ezrA"
                     /locus_tag="VYN12_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1415884.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASYVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4541..6487)
                     /gene="gyrB"
                     /locus_tag="VYN12_001526"
     CDS             complement(4541..6487)
                     /gene="gyrB"
                     /locus_tag="VYN12_001526"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1415885.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6502..7065)
                     /locus_tag="VYN12_001527"
     CDS             complement(6502..7065)
                     /locus_tag="VYN12_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1415886.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(7150..7704)
                     /locus_tag="VYN12_001528"
     CDS             complement(7150..7704)
                     /locus_tag="VYN12_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1415887.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7715..8938)
                     /locus_tag="VYN12_001529"
     CDS             complement(7715..8938)
                     /locus_tag="VYN12_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1415888.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8975..11425)
                     /locus_tag="VYN12_001530"
     CDS             complement(8975..11425)
                     /locus_tag="VYN12_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1415889.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11625..12554)
                     /locus_tag="VYN12_001531"
     CDS             complement(11625..12554)
                     /locus_tag="VYN12_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1415890.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVHKLHPKNRFLDTGFYDYDPDMVR"
     gene            12694..12981
                     /locus_tag="VYN12_001532"
     CDS             12694..12981
                     /locus_tag="VYN12_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1415891.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(13015..14349)
                     /gene="ciaH"
                     /locus_tag="VYN12_001533"
     CDS             complement(13015..14349)
                     /gene="ciaH"
                     /locus_tag="VYN12_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1415892.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(14339..15013)
                     /gene="ciaR"
                     /locus_tag="VYN12_001534"
     CDS             complement(14339..15013)
                     /gene="ciaR"
                     /locus_tag="VYN12_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1415893.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            15231..>15654
                     /locus_tag="VYN12_001535"
     CDS             15231..>15654
                     /locus_tag="VYN12_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415894.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDF"
BASE COUNT         4813 a         3276 c         2844 g         4721 t
ORIGIN      
        1 atattctgct taaaattcgt attggcaagc ttgaagtaag tttttttcaa tctctcaatc
       61 tcgaaatggt agaacagctt ttggataagg tgttgctcta tgacaattca tctatctagc
      121 ctagggcagg tctatctcgt atgtgggaaa acggatatga ggcaaggcat tgattcactg
      181 gcttatctgg ttaaaaccca ctttgaatta gatcctttct ccggtcaagt ttttctcttt
      241 tgtggtggac gtaaagaccg ctttaaagcc ctttactggg atggtcaagg attttggcta
      301 ctatataaac gctttgagaa cggcagactg acttgaccca gtacagaaaa ggatgtcaaa
      361 gctctcacac ctgaacaagt agactggctt atgaagggct tttctatcac tccaaaaata
      421 aattcatcag aaagtcgtga tttctattga aatgaggact ttctttttag tatagtgaat
      481 tgaaataaga tatgaacatc tctatcagga aagtcaaatt aatttataga aatattttag
      541 cagtcaaggt gtactgttat agattcaata cactatataa taaagttagg aaataaggag
      601 gaaagtctat gggagaagat tgaaaatcat tcaacaacag agtgctacaa ttgatagtct
      661 caccaatgaa cttgcccttc ttcgtgaaca agtggcttat ctaacgcaaa agctctatgg
      721 aaaatcctct gagaaaagtg tttgcccatc tggacaactc agtctttttg aagaggaaca
      781 aaatatggaa gaagactctg acttacccag ttgaaagaga agaaatcacc tataaacgta
      841 agaaagctaa agggaaacgt caagctattc ttgcccaatt tgattcagaa gaagttcatc
      901 atcgcttaga gaactgcatt tgccctgact gtcagggaga gctaaaagag attggagcga
      961 gccttcaacg acaagaattg gtctttattc ttgcgcaatt aaaaagagtg aatcatatcc
     1021 aacacgctta caaatgccaa acatgcagta agaataatcc aagtgataaa atcgtgaaag
     1081 ctcctattcc taaagcccct ttggcgcata gccttggctc agcttctatt atcgctcaca
     1141 ccatccatca gaagtttatt ctgaaggtac ccaattatcg ctaagaagaa gattgggcta
     1201 agatgggttt accaatcaca cgtaaggaaa ttgctaattg gcatatcaag gcgagtcaat
     1261 actatttaga gtccctttat aaccttttac gagaaaagtt gttagaacaa gctcttcttc
     1321 atgcagatga aacctcttat cgggtcttag aaagtgatag tcagctgact tactattgga
     1381 cttttttgtc tgggaaagct gagaaacaag ggattacgct gtaccaccat gatcagcgtc
     1441 ggagtggttc ggtagtgcaa gaattcctag gaaattattc tggctatatg cattgtgata
     1501 tgttgcggca gtaacttaga actttagtcc tctagttctg cctatgcgat agcagtctaa
     1561 ggtttaggag caaggcgacg ctaagcttgg taaactgcga accgctagaa gcttatcgtc
     1621 aactggaaga agctgaactt gttggatgtt gggcgcatgt gagaaggaaa ttttttgaag
     1681 cgacccccaa gcaagcagat aaatcatcct taggagctaa aggtttagcc tatcgtgacc
     1741 agttatttgc cttggaaaga gactgggagg ctttgccagc tgatgaacga ctacagaaac
     1801 gtccagcccc taatggaaga cttctttgct tggtgccgcc gtcagtcagt tttagcaggt
     1861 tcaaaactag gaagggcaat tgaatacagc ctcaagtata aagaaacctt taagaccatt
     1921 ttaaaagacg gacatctggt cctttccaat aatctagctg aacgcgccat taaatcattg
     1981 gttatgggac ggagtaaaag agtccagtgg actcttttag cctgagctca gtttaaaaaa
     2041 gcgagggtgg ttattttctc aaagttttga aggagctaaa gcaagagcta ttattatgag
     2101 tttgttggaa acagctaaac gtcatcaatt atagtgcgtt gaatctataa cagtacgcat
     2161 cgactgctaa aatatttcta taaatcaatt ttcctttcct aatcgatttg ttcatatctt
     2221 atttcaatcc attataaata gcgagaaata tctatcctat cttctagaat gtcttccaaa
     2281 cgaggaaact ctcgtaaaca aagaggtttt agaggcctat ttaccgtgga ctaaagttgt
     2341 acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct
     2401 ggagattttt caatagactt cgttattgga cggttaccaa gttactcaaa gtacagattt
     2461 gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac
     2521 taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag
     2581 agattttcga agagtataaa acactgtttt gaggtggtgg ataaatcggc tgggtaaaaa
     2641 ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag atttgattct
     2701 gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct
     2761 catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat gcttgagaaa
     2821 tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa
     2881 atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct
     2941 ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat
     3001 tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact
     3061 caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg
     3121 gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat
     3181 aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac
     3241 taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt
     3301 cttcaagaac tgaataagct tgggttggtt cttcttgatt tgaagttacc tcaacaatag
     3361 ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atagcttgca gctgtctcag
     3421 gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt
     3481 tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag
     3541 caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct
     3601 catattcggc attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt
     3661 cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa
     3721 ttagtttacg ataaccggat tccaaatcct gtaattgatc tggcaattct gtagaaagcg
     3781 tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg
     3841 tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt
     3901 gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat
     3961 actgttctga attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa
     4021 gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg
     4081 ccgcaatatc ttcgtcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg
     4141 ccttgagaaa acgaaatgaa tggttatagc cttctgcttc aaagagatta ttttcaatat
     4201 cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt
     4261 gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat
     4321 tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt cgcttacgta
     4381 gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa
     4441 ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata
     4501 tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat
     4561 agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat
     4621 caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt
     4681 cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac
     4741 gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga
     4801 tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat
     4861 agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc atataacgat
     4921 aaatcaaggt taaaagaagg gtacgaatgt gggctccatc gacatcggca tcggtcatca
     4981 aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca
     5041 tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt
     5101 caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag
     5161 atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt
     5221 tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt
     5281 tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct aaaatccctt
     5341 tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac
     5401 tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc
     5461 cttcaaactg tggatttggg tgtttaactg agataactgc agttaatcct tcgcgaacat
     5521 cttcccctgt taaattatct tcattgtctt tcagtaactt attcttacga gcataatcat
     5581 tgataacacg agtcagtgcc gtacggaaac cttgttcatg cgttccacct tcatgggtat
     5641 gaatattatt ggcgaaactc atgacatttt catggtaacc tgttgtgtac tgcatggcta
     5701 cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat
     5761 ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct
     5821 tggtttgttc caaaccttgg cgcttatctg taattgaaat ttgaagaccg cgatttagaa
     5881 aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaagattgtt gtttcagtga
     5941 aaatttctgg gtccggtgtg aagtgaaccg ttgttccagt tctatctgta tccccaacca
     6001 cctcaaggtc tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccgtttt
     6061 tatggacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt
     6121 gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagca tgaaggactg
     6181 taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac
     6241 gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg
     6301 caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa
     6361 gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc
     6421 cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt
     6481 ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt
     6541 aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc
     6601 aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt
     6661 tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga
     6721 ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc
     6781 accttgattt aaaatgtctt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc
     6841 aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa
     6901 tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt catggtcttg
     6961 tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc
     7021 cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc
     7081 atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata
     7141 actcccgttt tactgatttt taccaaagac atctcgatag agcattcctg ttcgtaaact
     7201 ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg
     7261 accccgactg gttgtcaact gaccatctac cactactgtt tccttgacgt agtgaccatc
     7321 aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc
     7381 ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa
     7441 gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc
     7501 tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat gatctgctct
     7561 tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat
     7621 attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc
     7681 taacataact gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct
     7741 ttttccgttt gaatgggact tttccgctct tttcttcagc taaattagtc tggtaactca
     7801 tcgataaaag caaaccaaca ccaatcaaat tactgataat agctgatccc ccttgcgaaa
     7861 tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa
     7921 agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat
     7981 ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca
     8041 ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc
     8101 gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa
     8161 tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga
     8221 gccaagccaa aatccgatta atttggtagg tcggcattcc aatctggtga agaaaagctc
     8281 gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa
     8341 atactgggat aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg
     8401 ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa
     8461 tggtaaagag aatcatccag aaaattaaca aaaagtccag cggaaccgtg cgtctccatt
     8521 ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata taggatatct
     8581 tcataaattc tgacggttga aatagggtaa ttccatttat tgatacccag tttttggcac
     8641 ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata agtcccaagc
     8701 ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca
     8761 caaaaccaat cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa
     8821 tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg atgaccagta
     8881 gaaaaaatac tggcaagagc aaactataat cgactctaga gtcgagagaa cgtttcatat
     8941 gtactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa
     9001 tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagatg
     9061 ctactatttg tttgccgtat cgttttccga cgattctcct atccaaaata agagttaagg
     9121 aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca
     9181 ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct
     9241 ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacag
     9301 aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt
     9361 gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca
     9421 agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa
     9481 ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat
     9541 agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccataacc acttcttgtt
     9601 cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct aaaaggtctg
     9661 ccaaagaaac cctctgacta atctcaagag tagccgatac tcccaagact tggcaactct
     9721 caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaatc tgaattttct
     9781 tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca
     9841 gctcatcaaa gccttccact tctaattctg aaaaatactg atggagattg tccagagaat
     9901 ctaagatatt tttcctagat ttaccagact gaaattgttc tatcaagtag agacactcaa
     9961 agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat
    10021 caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta
    10081 acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat
    10141 cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc
    10201 tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat gataaattcc
    10261 catcatgacg aaggtctgct agaaaatgtt ggtaacggta gagttgcccg atttcatcca
    10321 aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata
    10381 agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt
    10441 gtggtccctt taagctatga atatctgtat ggaacacttc cttgaggcgt ttaccttctt
    10501 cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt
    10561 tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt
    10621 gaatcagaga gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt
    10681 gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt
    10741 ttcgtagctc cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt
    10801 ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat
    10861 ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga agctgggtca
    10921 tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt
    10981 gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca
    11041 gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat
    11101 agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta
    11161 caaaaatccc atcctccacc aagtcaaata tttttctggc aacttgcgaa aaatcaggtg
    11221 cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt
    11281 catgtggatt gacatccgtc gtatagtgat cgacgatttc tccatcctca atcacgacaa
    11341 ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa
    11401 catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc
    11461 acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttaa aaatcccatc
    11521 gaatagagca ttctagcctg ctgatttttg taaaatagtg aagaaatacg aaaaattgag
    11581 agaagaaatg tttgcatctt ccttctctca acgaatcatg tattttatct aaccatgtca
    11641 ggatcgtagt cataaaatcc tgtatcaagg aaacggtttt tagggtgaag tttatgaact
    11701 tcttcatcca gcaagaaggc ttgatcatgg ctaaagttgc cctcttgaat caaattacgc
    11761 gcttggataa agagttttgc aatctcaaca aagttctgac caggagtgta gagcccttct
    11821 agtttccagc gagtaaagcc atgctccacc aattctgtta atttgatcat caaatcaagg
    11881 tcattgttgg caaagatatg ggtcccatga ttatcttcaa aaatggaata gtggctctct
    11941 ggatcacttg gctcagccaa gaagaggtca cgtttatgcg tcttttcatc atcgatatgt
    12001 gtaaagttat agtagttttg caagagtgga cgtttagaat gatggatgac gctagcaccg
    12061 taaaccaaaa cttcagcagg aatttccaaa atctctggca ttttgaaaag ttcagctgat
    12121 ggaatttcac gcgccaaaac agcctcagat gcgccagcct tttgtcccca gaagttaatc
    12181 tgacgactgc tagttaccat ggttgaagca tcgtagatgg tcttaaatga ataaccatcg
    12241 cggttaacta cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct
    12301 tccaagaagt ctaagaaagg cttgatacgg tccatcatat cttggtgcat gagagcattg
    12361 accgcaacga tcaattcctt accagcatca tgaaccaact tagcgatttc acgtaattgg
    12421 tcataactaa aggtcgttgg cagacgaaga ccaaaatctt tctcaccgac atagatacgg
    12481 tctacgccag cttcgagtag ttgttcaact tgttcaatac tttcagcagt tgctgtaatg
    12541 acaatctttt ccataggaaa aattatacca catttctcca aaatcagcca tgctttgaaa
    12601 atgaaaaggg actttattct ttttgtaacc tttctgtaat aattctctgc cgaaaaaatg
    12661 ataaaatagg tatgtactgt taaggagaga atcatgcccg taagaaaatt acaatcctat
    12721 gaggtagact atcaagaaga attaaaccag cagcttcctc attaccaagc ttatacacct
    12781 gaagcgcaat ctgatgccaa tctcaaggaa atcctatttt ttattaatat cgctgttttt
    12841 tgtatctgta ttgctatctt tagttttatc tttttagcat taaaattatc aactgctctt
    12901 gcctttgccg cagcaatcgg attcagctta cttgttttaa aagttcaacg gtctattatc
    12961 aaacgaaaac gtagaagata aatccaaaat atcgccccaa ttggagcgat atttttattt
    13021 tttcttttta gatggtgtct gaatggcaat cttcacttca aagattgttc ccttgggttt
    13081 attatctttg acagtaacag ttccttttag agcatctaca atttgcttgg ctagggataa
    13141 tcctaaacca aaaccacctt tttgccgggt tctagctttg tctactcgat aaaaacggtc
    13201 aaaaattttc tttttatctt ctgtcgaaat accgattcca ttatcagaaa caagtaaata
    13261 aagattgcga tcggtcgccg agataagaaa atcaatttca ccatcctcct cagtatactt
    13321 gacggcatta tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat ctgtgacaat
    13381 tgttcgatgg atacgatttt caaaacggaa gacacgatta ttttccgaag caatcatctc
    13441 atagtttgtg aaagttgtat taaaaaagct agttggaact tctgcaagct ccggcttaat
    13501 cccatcatct ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac
    13561 ttcttccaaa ctcgatgcaa tgctttcgct cacatccata atggtagctt ctggcttacg
    13621 aaaaagggtc tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact catgactggc
    13681 attttccaca aaagactgtt gcttctgcat actctcaagc aggggcctaa cactgaccct
    13741 agctagatag agactggcaa gtaaagacaa aatccagaaa ctagccatca cgaccacaat
    13801 caattgctca tgcttttgac tagcctgctc caactgactg gtattaatca agacagcagc
    13861 atacttgata ttggttgaaa ccgaactaat attggtctcc atcaaaatca cacgatagat
    13921 ttcttcctgc ccatagctat taaaaacctg aatctggtag atatgtccta gttctttctt
    13981 ttctaactta atcttatcca agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc
    14041 tttatcaaag agaatgactt ccgtattgga actgacatta ggttttattt ctactttact
    14101 agcgtccgcc ctagcatttt ctaaatcttt aatctcttct gttgccctat ttatagccag
    14161 ctgaataact gcttgaggat tttcactcag tccatgaagc ttatcgtcca ccgaagtata
    14221 aagactcgaa tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa
    14281 gacaccgaag ttgcggataa aataactaaa gtcatccgca taccatgttt ttttaagttt
    14341 actgaacatc ttttaaaaga tacccaacac tacgcaaggt ttgcaaattc tctgcaaaag
    14401 tggttccctt taatttctta cggacttttg aaacatagac ttcgacaacc gaaatcgttg
    14461 tatcactatc aaatccccat agacggtcaa aaatctgcgt cttaggcaaa atcacatttt
    14521 gattttgaag gaaataaact agtaaatcga actctttccc cagcaattcg acaggagtat
    14581 cttcaacttt aacggtattg gttgataaat taaccacgat attcccataa gtcaaggtgt
    14641 tttcattaaa cttccctgaa cgtttgagaa gggcctgaat tcgcatttta agttcttcta
    14701 ggtagaaagg tttggtcaga taatcatccg ctcccagttc aaatccatgt cccttgtcat
    14761 ccaaactttc cttggcagtc ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt
    14821 cttttaagac ttggaaacca tttttttctg gcaacatcaa atccagcaaa atcaagtcat
    14881 agacaccact ctcagcttcg tagagacctt cttctccatc aaatacctgc ataacatccg
    14941 caaaatcgtc taaaaagtca aatactgaat ttgacagacc taggtcatcc tcaaccaata
    15001 agatttttat catgagaaac tcctccttat taaaactatt ataccaaatt tgccttaaaa
    15061 aaaactcaac tctctgcatt ttacatgaga tagctgagtt ttctttggct ctataatatt
    15121 tgtagtgggt aaatccacta tggatattat ggagcctatt ttattgtaga aaaaaagtcc
    15181 catatgacct ataatgaaaa gcgacaaaac aactcattag aaagattcat atggaacaat
    15241 tacattttat cacaaaactg ctcgatatta aagacccaaa catcaagatt ctagatatca
    15301 tcaatatgga tacccacaaa gaaattatcg ctaagctgga ttatgaggct ccatcttgcc
    15361 ctgattgtgg aagtctaatg aagaaatatg actttcaaaa accgtctaag atcccttacc
    15421 tcgaaacaac tggtatgcct tctagaattc tccttagaaa acgccgtttc aagtgctatc
    15481 actgttcaaa aatgatggtt gctgagactc ccctggtaaa gaaaaatcac caaatccctc
    15541 gtatcatcaa ccaaaaaatt gctcaaaagt taattgaaaa aatttctatg actgatattg
    15601 cccatcagct ggccatttca acttcaactg tcattcgcaa gctcaatgac tttc
//
LOCUS       DAVLTG010000042        15121 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLTG010000042 DAVLTG010000000
VERSION     DAVLTG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.043"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(148..1344)
                     /gene="tuf"
                     /locus_tag="VYN12_001536"
     CDS             complement(148..1344)
                     /gene="tuf"
                     /locus_tag="VYN12_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1415895.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2255..3124)
                     /locus_tag="VYN12_001537"
     CDS             complement(2255..3124)
                     /locus_tag="VYN12_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1415896.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3347..3868)
                     /locus_tag="VYN12_001538"
     CDS             complement(3347..3868)
                     /locus_tag="VYN12_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1415897.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(3826..4905)
                     /locus_tag="VYN12_001539"
     CDS             complement(3826..4905)
                     /locus_tag="VYN12_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1415898.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEELAE
                     LISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGRQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5016..5270)
                     /locus_tag="VYN12_001540"
     CDS             complement(5016..5270)
                     /locus_tag="VYN12_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415899.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(5628..6161)
                     /locus_tag="VYN12_001541"
     CDS             complement(5628..6161)
                     /locus_tag="VYN12_001541"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1415900.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPVLYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVMDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6148..6363)
                     /locus_tag="VYN12_001542"
     CDS             complement(6148..6363)
                     /locus_tag="VYN12_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415901.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6330..6473)
                     /locus_tag="VYN12_001543"
     CDS             complement(6330..6473)
                     /locus_tag="VYN12_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1415902.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            6707..8425
                     /locus_tag="VYN12_001544"
     CDS             6707..8425
                     /locus_tag="VYN12_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1415903.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8536..8883
                     /locus_tag="VYN12_001545"
     CDS             8536..8883
                     /locus_tag="VYN12_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1415904.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9162..9998)
                     /locus_tag="VYN12_001546"
     CDS             complement(9162..9998)
                     /locus_tag="VYN12_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1415905.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10011..10640)
                     /locus_tag="VYN12_001547"
     CDS             complement(10011..10640)
                     /locus_tag="VYN12_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1415906.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10650..11291)
                     /locus_tag="VYN12_001548"
     CDS             complement(10650..11291)
                     /locus_tag="VYN12_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1415907.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11437..12666)
                     /locus_tag="VYN12_001549"
     CDS             complement(11437..12666)
                     /locus_tag="VYN12_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1415908.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELYDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILELQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEYYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(12656..13822)
                     /locus_tag="VYN12_001550"
     CDS             complement(12656..13822)
                     /locus_tag="VYN12_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1415909.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            13966..14979
                     /locus_tag="VYN12_001551"
     CDS             13966..14979
                     /locus_tag="VYN12_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1415910.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
BASE COUNT         4561 a         3224 c         2704 g         4632 t
ORIGIN      
        1 aatatgtact attctagttt caatatatta tagtttgctc tttgattttc attgagtatt
       61 agttcaatat ctaaaaaaag aaccttgcca agcaagattc ttttagtgtc tgacttaaat
      121 aattgttctt ctgggaacta aatcgaatta agcttcgatt tctgtaacca tacctgaacc
      181 aacagtacgt ccaccctcac ggatagagaa tgtagtacct tgttctacgg cgattgggtg
      241 aatcaactca acgtcgattg tcacgttatc accaggcatt accatttcag tacctgctgg
      301 aagttcgatt gaacctgtaa cgtcagtagt acggaagtag aattgtggac ggtagttgtt
      361 gaagaatgga gtgtgacgtc caccttcttc tttagtaagg atgtagactt cacctttgaa
      421 tttagtgtgt gggttgattg aacctggttt agcgataact tgtccacgtt cgatttcatc
      481 acgttgaaca ccacgaagaa ggacacctac gttatctcca gcaagacctt cgtcaagttg
      541 tttacggaac atttcaacac cagtaacaac tgctttttga gtttcttctt tgataccaac
      601 gatttcgatt tcgtcgttga ctttaacgat accacggtcg atacgtcctg aagcaactgt
      661 accacgtcca gtgattgaga atacgtcctc gactggaaga agcaatggtt tgtcagtgtc
      721 acgttctggt tctgggatat actcatcaac tgtgttcatc aattccataa cgatgtcttc
      781 gtatttagag tcaccttcaa gagctttaag tgctgaacct tggataactg gaagatcgtc
      841 acctgggaag tcgtattctg acaataggtc acggatttcc atttcaacca attcaagcaa
      901 ttcttcgtcg tcaaccaagt caactttgtt catgaagacg ataaggtgtt taacaccaac
      961 ctgacgtgaa agaaggatgt gctcacgagt ttgtggcatt ggtccgtcag ttgaagctac
     1021 tacaaggata gctccgtcca tttgagcagc accagtgatc atgtttttaa cgtagtccgc
     1081 gtgtcctgga gcgtcgatgt gagcgtagtg acgtttttca gtttcgtact caacgtgcgc
     1141 agtgttgata gtgataccgc gttcgcgttc ttctggagca gcatcgatag acgcatagtc
     1201 tttaggttgg ttaactgatg aaggcaagcg acgtgccaaa acagttgtga tagctgcagt
     1261 tagggtagtt ttaccgtggt caacgtgtcc gatagtacca atgttaacgt gtggtttact
     1321 acgatcgtat ttttcttttg ccatttgagt aaaagcctcc aataaaatat attttataga
     1381 tagacagtag gcaatacagt ctaactttcc ttactatttt atcaaatttc agctaaattg
     1441 caagtgtttt acaacgtttt tgtgaattat tcttggtaaa aatttaacta actaatagaa
     1501 agtactaaat agacttatcc ttcaaggagt tttcagcatt atccatccac tcacttgctg
     1561 aaaatgtaaa cattctctgg tttatatagt aaaatgaaac aagaataggg caaatcgatc
     1621 aggacaatca aatcgatttc taacaatgtt ttagaagttg aggtgtacta ttctagtttc
     1681 aatctactat acaacctcaa aactgtgttt tgaacaacct gcggctagct tcttagtttg
     1741 ccctttgatt ttcattgagt ataaaattgc agataaaacg ataacaatca taggactcag
     1801 cagagtcaat gtaggtcgaa gaatagcccc cctaatcgct tattttatag caaaatgaaa
     1861 tagaaactga acattttgtt gaggaaggta aatcaattcc tcacaatgtt tgagaaagaa
     1921 gggaggacta ttccaacttc aacccactat aaagcagact tacaagatag ggaacccatc
     1981 tccgataata tatagtagaa tgaaaactgc acaatttgat tggagaattc aaaccaattt
     2041 ctaacaatgt tttagaaaca agggtctatt atttcaactg caacctacta tagcccattg
     2101 aagctggaat agcccactga gacttctaaa ccactgctgg agaggagttt gtttagagtt
     2161 tctttcattt ccctaaaaaa tcaaaaagag agaaccagtc tgatcctctc ttacttatag
     2221 atggtgctca ctcaaatgtt aaaggagcta tttcttagag ataaaggaat ttgaatacag
     2281 ctactgccgc aattgctgct gcgataggtg ctactactgg tacccaagaa taccaccatt
     2341 ttgaatcgcc tttatgctca ccaagaactg attttggaag gaaagcatga aggagacgtg
     2401 gtcccaagtc acgggctggg ttcaaggcag gtcctgtagg tcctccaagt gatgttacca
     2461 aagccataac gaggaatcca agtgccaagt gagccacaga aagtcctgaa gcagtgtgtg
     2521 gagccacctg tgctttaata gccaagtcag aaaaatcaac tgtttgtcct gcttctattg
     2581 ccttttgttt catgaattga agcacttcag caccaaagaa gtttttagtc aaaccaagag
     2641 ctgcaaagaa caaaacaaat gaaccaacaa actcattaat caaaccattg acagttgctg
     2701 catagcgact ttcttttgta ccatggtcaa tacttgaaat agttgagaaa gttcccaaga
     2761 tgttatttgg tttttcagtt ttcaagtaga atggacggta tgttgccaca actaaggctt
     2821 ggccaaagat agcccccaag acttgcgcga taatgtaagg taccacttgt gcccaaggga
     2881 aaagaccact aactgcaagc cctagagtga aagcagggtt gatgtgattc ccagatacgt
     2941 taccaaacat caaggctggg atcataaccc ccataccata accaacagcg atgacgatcc
     3001 agccactttg gtgacctttc gtacctttaa gttcaacgtt ggcaactgca ccattcccaa
     3061 gaatgatcaa aatggcagtt cccaaaaatt cagtggcata cttcagtgcc catgtgaaat
     3121 ccatttgcta gattctcctt aaaatttttt agatattcct tattttatca atttttaccc
     3181 tatttagcaa ctgatttctg gaaatatttt taaaaaaata ggattcatag tttcccagtt
     3241 caacgtactt gtaagcgttt ttattcttca cgaaagacct cattctcaaa accaggaaaa
     3301 agcccacatc tgtgatcttt tccttgttcc tagattctaa aatctattat ttttcatctt
     3361 cttttttctt gaagaatcct aatcctagac cagctaacaa ggtcatgata ccagcactag
     3421 ccaaggtagc attagcttct gtacctgtgt ttggcaattc ctctctctta cctgtctcat
     3481 aagtcggaac ttctgggtct ggattcactg gagtttcagt ttttggagta cctggttctg
     3541 gagttggttt atctggtgtt gataaacggt cataccttac cgttatttct ttatcactag
     3601 agtctgacgt aacttcttgt gattcaactg ttggaatatc tggatctttg tacttgtcaa
     3661 tcttaccaga tataacctcg tcccagtttc ctgttgtcca ttcaccgtag gttacaactc
     3721 ccgtgacctt gttctcagtt tttgtacggc ttaaggttac aggttgaaca acatcttctt
     3781 ttacattttg gttcgtaact ttatcaacgt aatgaatgat acgcgttata gtcttcgtct
     3841 cagtagaggt tgctgttttg ggaaccactg tttcctcaac attctcacgg tagtaatagt
     3901 caactgttgc accgtcttct ggtacgcatt tgcaggagtt gctaccaagg tgtatgttgt
     3961 tttccttgtg ataactcggt cttctttgtc ctcagttgtt gttttccctt caatagtttt
     4021 tgattctgtg gtatactcag aacctatcgc taaatcagct tttataacag actctgccaa
     4081 cttctcttgc ctaccttctt tatagtaatt ggctgttact gtagcagtgg ttggcgcttc
     4141 gctttctcta taaactaagg tcactgttct accttcgctt acaatattcc cagttaaact
     4201 tgcagaattt gtatctgctt ctttaaaagt ataatatttt ccgtcagtag tagtcatgct
     4261 actgagtttt ttatctgtga cattatagct ggtaccaatc agttgttttt tattggtaat
     4321 gtaggttccg tcactttctt tttctccaat tccagtatca tttttcaatg atagcaaacg
     4381 cccttgttca tcaacatagc gaactttcac attttctgag attagttctg ccaattcttc
     4441 ggttattttc cctttctctt cttcgggaat atttagtttt ggaatgattt tttcaacaac
     4501 ggttcgtgat ggttccacag tatcttggat gactgaaaag tcagctagaa ttgggagatt
     4561 atactgaaca cggtaacttt gagtgtttac tcctactctt tcattattct ctgaaaatac
     4621 ttgtacggta taagaaacaa catcttttcc taatagaaca tccccagtag agaaatagcc
     4681 gccttttcct agtttgctat ctccagagcc cacttctttc ctaatcttat cagatagttt
     4741 tttaccagtc agtacattcg ttcgcacaat ccctttgtct acccctacaa agtgggagaa
     4801 ctttttgaac tcttcagaac cagatctagc ccaaccatta ttaagggcat ttgcttttgt
     4861 atttgtattc tctctcaaag gtttggcgat tagaattata ttcatcggca cttagagttg
     4921 ctgctatatc tgactcttga ataccaactt ccttactacc atttctagcg gcagtatatg
     4981 tgtatttatc tgtttctact tctagctgat tatccttaac atgataggta attttctcct
     5041 ggtataagag tcttcagtag tttatatact ctgtcatcat ctttagcttt agaagcagct
     5101 gagtttagcc aagttggggt attaggagta tctttatcaa cctgtttcaa gacattattc
     5161 aagtcatttg ctagcctatt ggttatcctc actgtgaaag ttttcttcca gtctgaacca
     5221 cttttattag acttagatat gctcatgaaa tcctggtcaa cattcaacac aatatcgcct
     5281 tgttttttag tatcttccgt tgcttctgct tcaaattgat catggagttt ttgttgctct
     5341 ggtgtatagt ttttttattt acacgattta atgtactatt ttttatttta gtattaagaa
     5401 ctccattaat acgattttta aactctgctt caaaaaatcc cttaatttgt tggtgcgcaa
     5461 gttcaacatt caaacctttc ttatacaagt cttcattctg atacaagtct tcattctgaa
     5521 cgatttcggc tacacggtga atggtttgat cgtataccgt cttctcttaa ccagcagtat
     5581 ccttagtttt aatgactact cgataggttc ctttagaacc gttatagtca tctagtttta
     5641 aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc ttaataaatc catcactttc
     5701 tttttcaaga tagcccaagc ttgctcaata ggattcaaat ccggtgaata aggtggtaga
     5761 ggtaagaaaa agtgtttatc ttggatgcag agttcatcca aaatgttctt gggatgaaaa
     5821 ctagcattgc ccatgacaat aacatgaggt gtcttcaaag caggtaggag ttgcgttttg
     5881 aaccactcca caaagaaatc gcttgtcatg cttttcttgt aaatcatggg agctataaac
     5941 tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc gctaatcttt
     6001 tcatagactt tctcccctct aggagcccct gcataaggac gatagaggta gcggtcgatt
     6061 cctgtttcat caatatatag gactggtaaa tcttttaggt tatccaaaat atcaagaaac
     6121 tcagcgactt tctctggctc ttgttcctta aagctcgtca tcttttttta aagtgacctt
     6181 aatctgcttt aaagctgccc atactgaagg aacagcacaa tcaaaatgtg ccgcaatttc
     6241 ccgtaaaaaa gcatctggat gagcctctac aaaggctttc aattcctcta aaggaatctt
     6301 tcggtttttg acgactcgct ttttcctctc tatgtgtcct tgttcacgtc tttcttttcc
     6361 cacgtgaaga gagttctgac gccaacacca aaaaactttg ctgcctcgac atggctgtgc
     6421 ccctctttga tgtaatctaa tgctcgctgt ttaaaatcag tactatatgc catagcttta
     6481 ttataatatg cttgtttaaa actaagcaac tatatcaatg ttttgttatg agaagactta
     6541 ctttttttac tgaaattgaa tttttcctag cctcaacatc atataacccc aaaattcaat
     6601 ctgacctggt ttgaagagat gttcgaagca gataaggttt tactaaaact aaaaaaaatg
     6661 atataattaa actgattaaa tgttttaaaa ataaaggaga atttgaatgt cttaccaaga
     6721 aaattaccag aaatgggttg attttgtgga gcttcctgac taccttcgtc aagatttgga
     6781 aaatatggac gaaaaaacta aggaagatgc cttctataca aatcttgaat ttggtactgc
     6841 aggtatgcgt ggcttggttg gtgctggtac aaaccgtatc aacatctacg ttgttcgcca
     6901 agctactgaa ggattggctc gtttgattga gtcaaaaggt ggaaacgaga aagaacgcgg
     6961 tgtagcaatt gcctacgata gccgtcactt ctcacctgag tttgcctttg aatctgcggc
     7021 agttcttgct aaacacggca tcaaatctta cgtatttgaa agccttcgtc cgactccaga
     7081 actatcattt gcagttcgtc atctcaactg tttcgcaggt atcatggtca cagccagcca
     7141 caaccctgct ccatttaacg gttacaaggt ttacggtgaa gacggtggac aaatgcctcc
     7201 acacgatgcg gacgctttga ctacttatat ccgtgcaatc gaaaacccat ttgcagttga
     7261 agttgctgat gtggaaactg aaaaagcttc tggcttgatt gaagttatcg gcgaagctgt
     7321 tgacatagaa taccttaaag aggttaagga cataaacatc aacccagcct tgattgaaga
     7381 atttggtaaa gacatgaaga ttgtctacac accacttcat ggtactggtg aaatgttggc
     7441 tcgtcgtgct cttgcccaag caggatttga ctctgttcaa gttgttgaag cgcaagcaac
     7501 tgctgaccca gacttttcaa ctgtaacatc tccaaaccca gaaagccaag cagcctttgc
     7561 ccttgctgaa gaacttggtc gtcaagttgg tgcagatgtt cttgtcgcaa ctgacccaga
     7621 cgctgaccgt gttggtgttg aagttcttca aaaagatggt agctacctca acctttcagg
     7681 taaccaaatc ggtgctatca tggctaaata catcttggaa gctcacaaaa acgctggaac
     7741 tcttcctgaa aatgccgctc tctgcaaatc tatcgtttca actgacttgg taacgaagat
     7801 tgctgaaagc tacggcgcaa ctatgttcaa cgtcttgaca ggtttcaaat ttatcgctga
     7861 aaaaatccaa gaattcgaag aaaaacacaa ccacacttac atgatgggat ttgaagaaag
     7921 cttcggttac ttgattaaac catttgtacg tgataaagat gccatccaag ccgttcttgt
     7981 agttgctgaa cttgctgcct actaccgttc tcgtggtttg acacttgctg acggtatcga
     8041 agaaatctat aaagaatatg gctactacgc agaaaaaaca atctctgtta ctctttcagg
     8101 tgtcgatggt gctgaacaaa tcaaagcgat tatggctaaa ttccgcaaca atgctccaac
     8161 agaatggaac gcaacagcta tcactgtcgt agaagacttc aaggcacaaa ctgctactgt
     8221 tgctgacggt actgttacaa acttgacaac tcctccaagt gatgtgttga aatacacact
     8281 tgctgacggt tcatggattg ccgttcgccc ttcaggtaca gaaccaaaaa tcaagttcta
     8341 cattgcagtt gtaggggaaa ccaacgaaga atcacaagct aagattgcta acatcgaagc
     8401 agaaatcaat gcatttgtaa aataaagacc tataaaagat gagaccaacc aacctcatct
     8461 tttttcgtat caaatctaag caattttaga aactttatgg catactagac ttatcaatga
     8521 aagcgaggta atctcatgga acaattttta gataacatca aagaccttga agtcactaca
     8581 gttgtgcgtg cgcaagaagc tcttgataaa aaagaaactg caaccttctt tatcggtcgc
     8641 aaaacttgcc cttactgccg taaatttgca ggtacattgt caggtgtcgt agctgaaacc
     8701 aaagctcaca tttacttcat caatagtgaa gaaccaagcc aactcaatga tttgcaagca
     8761 ttccgctcac gctatggaat cccaactgta ccaggttttg ttcatattac agatggacaa
     8821 atcaacgtcc gttgcgactc ttcaatgtca gcacaagaaa tcaaagattt cgcaggattg
     8881 taaaaaatca gctaacaagt cttaaaatca caaaaacgca taatgtaagg tgcaaaaacc
     8941 ttgatattat gcgttttatt gttcctaaaa cagttacatc agtatttcat tacagaacat
     9001 tttaattttg gaagtcaaat caatttttaa caatgtttta gaaatcacag tgggctattc
     9061 catattcaat tatccatatt caatcgctat tatcgttttc ctagattaca aaaaaaacta
     9121 cgttttgcta atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact
     9181 tctttggttg ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc
     9241 ttgtaaagac tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg
     9301 gctccaaccg caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa
     9361 acaccttctg cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt
     9421 cgatcgtttt tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta
     9481 ttagcgacaa tattcttcaa aagttctgga tttgcttcaa agtccgcata accagatgaa
     9541 ccagcttgag ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat
     9601 ttcttcgtaa ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca
     9661 cggcgttcgt ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat
     9721 tcagcttctt tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca
     9781 aaaacagctg tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat
     9841 cccattggaa caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt
     9901 gaccaattat ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca
     9961 gtcatcagac tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt
    10021 tctactttca ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca
    10081 atctgggtca tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat
    10141 tctggatcca gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata
    10201 gcacgcgcca aagccactcg ctgcttttgc ccaccagata gtgagaaagg ataggcctct
    10261 gcgtgtcctc ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc
    10321 tgcttcattc ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga
    10381 ggaaatagtt gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatcc
    10441 agctctaaag gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca
    10501 agcatacgta aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc
    10561 ttttcaggaa tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg
    10621 atatttcgta attctaacat ggcagcctcc tatctataat aactatactt cttctcaact
    10681 tttttggaaa taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac
    10741 ataggaacta gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa
    10801 attccgagag catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca
    10861 ctaggaagaa caatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg
    10921 ctaaacttta agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca
    10981 cggaaaattt ctgcaaaata agctgcatag ttgagaacaa aggcaataat agctgcagga
    11041 aggcggtcta aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag
    11101 agtaaggggg ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc
    11161 caatggactt gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc
    11221 agtgcaaaga cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat
    11281 aaataagaca tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag
    11341 attaccaagt atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa
    11401 aagagataaa ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg
    11461 catttgcaca tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc
    11521 aaaatgtccc aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt
    11581 caaatctcct gtcaactctt gataatactc ataagcagta tccaaatcgt ccatttcttg
    11641 ataagaacga gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaattc
    11701 tagaatatcc tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc
    11761 ttctgtatcc tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc
    11821 atacaattca taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt
    11881 ctctaatcct tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc
    11941 ctgactgtac ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa
    12001 gtagagggtg gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc
    12061 tgttaagtca tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa
    12121 tttccctaac tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc
    12181 ataaatcgag cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa
    12241 ctcactatcc aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc
    12301 ctccaataat ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt
    12361 cagagccaaa gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa
    12421 ggcttcttct atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg
    12481 aaaatcctct acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc
    12541 aagataagtt gccaattcat acagaagatc acttgaatca ttttctaaag ctttggcgaa
    12601 ataatgctca gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt
    12661 gttcactctt gacttcctca ccctctaatt catatagacc actgactacc ttataccatt
    12721 cgaaaatggc tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc
    12781 cccagatacc aaacatagat cctgaagtta acaaaacaaa gagaacatta atagggtgga
    12841 tgtttaattg acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta
    12901 cgataaagac aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta
    12961 gagcaggaag catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag
    13021 taacccccag cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta
    13081 ctgctacaat aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca
    13141 catctgataa aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat
    13201 agttacgcaa gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca
    13261 aggcaacaat cacttgagaa gccccgctaa taaaggcact cacccagttg actgcctgag
    13321 atgaaacctt acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta
    13381 attgaggtct gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta
    13441 tatcttctaa gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg
    13501 gaatggcgac tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga
    13561 tagctataac acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat
    13621 aatataacaa accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag
    13681 gtgaaaatag aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta
    13741 ctaaaaatac cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa
    13801 aatgtttctc tttttgctcc ataaatactt cctttctatt gttctctcat tataccattt
    13861 ttgaaacaaa ataactcttt tttaaagtgc ttacatctaa ttggatatct ttaatttact
    13921 tgtttttgtg atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt
    13981 tattttggaa cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca
    14041 gaaactggtc agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt
    14101 gcctttgacc agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt
    14161 gcagcctatc aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac
    14221 tgttatgttg ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga
    14281 caagtccttg tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa
    14341 cacagtggcc aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta
    14401 acacctgacc actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac
    14461 ctcgatcaag aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc
    14521 tcacgccata tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat
    14581 agtactatcg aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggttatt
    14641 tcaactttac cagaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa
    14701 gacggtaaat acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc
    14761 cttgcggacg gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt
    14821 gattttgatt tgacacccga ccaaaaattt ctcattgttg tccatcaaga ctctgacaat
    14881 gcaactgtct ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc
    14941 catgttcccg aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt
    15001 ggtattttca agttcatttt ttcggctcta taatatttgt agtgggtaaa tccactatag
    15061 atattatgga gcctatttta ttgtagaaaa aaatcccata agatctataa tgaaaagcga
    15121 c
//
LOCUS       DAVLTG010000043        15002 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLTG010000043 DAVLTG010000000
VERSION     DAVLTG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.044"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VYN12_001552"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VYN12_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1415911.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VYN12_001553"
     CDS             1319..2023
                     /locus_tag="VYN12_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1415912.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVSDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VYN12_001554"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VYN12_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1415913.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VYN12_001555"
     CDS             3367..4176
                     /locus_tag="VYN12_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1415914.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /locus_tag="VYN12_001556"
     CDS             4267..4509
                     /locus_tag="VYN12_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1415915.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMIHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VYN12_001557"
     CDS             4511..4765
                     /locus_tag="VYN12_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1415916.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4840..6711
                     /locus_tag="VYN12_001558"
     CDS             4840..6711
                     /locus_tag="VYN12_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEV1415917.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEQKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVFKNNEEKDHVALLGRIGSERVYRYINKKYLDLPETFENYNVFVPEANG
                     SGALGEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVT
                     QHNSRKTWYYVPLQDFTVNSDIDWTQSVTDIDRQLDQKYDLSPEEIAFIENHVREMD"
     gene            6876..10130
                     /locus_tag="VYN12_001559"
     CDS             6876..10130
                     /locus_tag="VYN12_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1415918.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(10516..11502)
                     /locus_tag="VYN12_001560"
     CDS             complement(10516..11502)
                     /locus_tag="VYN12_001560"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1415919.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11696..14164
                     /gene="gyrA"
                     /locus_tag="VYN12_001561"
     CDS             11696..14164
                     /gene="gyrA"
                     /locus_tag="VYN12_001561"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1415920.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            14164..14907
                     /gene="srtA"
                     /locus_tag="VYN12_001562"
     CDS             14164..14907
                     /gene="srtA"
                     /locus_tag="VYN12_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1415921.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4832 a         2535 c         3263 g         4372 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctctggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt tcagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtcctcttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggttat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgcctc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaac aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctggacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tccatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attgaattac ttttttcaag taaattttca ttctttaaaa
     4801 tatgatataa tagggcttac aatataagag aggttgctga tgacaataga tattagtgaa
     4861 gaaagtttgg ctaaagaatc ggctgactta ttaaaaattc ttttaaaaga tcgaacgaca
     4921 aagaaatcaa ttgtttgggc tacgcattct tatgaattgt taggaaaggg atttgctcca
     4981 agtgatcgca tcaatccaag taaggttact ggaaactttg ccaacttgat tcagcccaga
     5041 tctgaaaaat ccaaatatga acaaaaagat cggacaaaaa taagggcaga agtgtttaca
     5101 ccaacgtggt tggtcgcaaa gcaaaatgga tatgtagaat cgaaattagg ctcgttaagt
     5161 cttgaggagt atgtggactt acgatggtta gaggtaactt gtggtgaagc accttatatg
     5221 gtaacgagat atgataccgt aactggtgag gaaattccat tatctgagcg agttggtttt
     5281 gttgatagaa aactgcaacg gattagtcgt gaggtttcag atgaagtcac attttataaa
     5341 cttgtaaaag atgcttatca tgcttcgtat ggttatgagt atcaaggaga ttctctcctt
     5401 ttggcgcgtg agaatctttt ggcaactttt gaggactatt atctagctaa gactggaaat
     5461 caaccaacat tagagcaaaa gaaagaaatt gcgactatta tctcttacaa tgtctttcag
     5521 atggatggat tgaaaaaaag tagtccttat tcagctaaac aaaagcaatc tcaacaattg
     5581 agtttgtttg cggatgagct agaagtccaa gaagtagaag aatctaaaac ccatatcaaa
     5641 gactggaaaa agaatagaat gataggtttt gagcgcctat ctagcgagga aagtgaaatg
     5701 aaatttgatg tcgtgatagg aaatcctccg tatcaggaaa caggagaagc cagagatgag
     5761 ccgatatatc actattttat tgatgaagct tataaaatcg cagataaatc tatactaatc
     5821 accccagcaa ggtttttatt taaagctggt caaactccta aaaattggat ggaaaagatg
     5881 cttgaagaca agcatttaaa agttcaattc tatgaactta aaagcggtaa agtatttaca
     5941 ggaacggata ttaagggtgg agtagcaata acttatcgtg atgttgataa agatttggga
     6001 ccaatcggag tatttactat ttttgaaact ttgaatggta ttgtaaaaaa aatcgaaaaa
     6061 catccagaat ttgaaacttt ttctgattta gtttatcctc aaggtattta tagattttca
     6121 aataaacttt tttctgatta tccaaatgct gaaaagctgc aaggaaaagg gacaaaaaat
     6181 aaaattgttt cgaaatcact aactcagtta gattttgttt tcaaaaacaa cgaagaaaaa
     6241 gaccatgttg ctctacttgg aagaattggc tccgaacgtg tttatcgata tattaataaa
     6301 aaatatttag atttaccgga aacattcgaa aattataatg tttttgtacc agaagctaat
     6361 ggaagtggtg ccttaggtga agtcttatca acacccctaa tcggggaacc cctaatcggg
     6421 catacagata cttttttatc tattggtaat tttaaaacaa aatttgaagc cgatgcttgt
     6481 attaaattta ttaaaactaa attcgctaga gtattattag gtgttttgaa agttactcag
     6541 cataattcac gcaaaacttg gtattacgtc cccctccaag actttacggt caattcggac
     6601 attgattgga cacaatcagt gactgatatt gaccgccagc ttgatcaaaa atatgacctt
     6661 tcccctgaag aaattgcctt tattgagaat catgtaaggg agatggatta gaaaagtatt
     6721 tttatttgac aaatagtgct caatgatcta aaatgactat ataggattag gtcaggaagc
     6781 atacgatgcc ctgacccttt ttgtacttat gagatgagaa agtcatttgt tagataaatt
     6841 gacttcgtta gcaaacgttc aaaaaaggaa aacttatgcc agtagaaatt aaaaccacta
     6901 aagaaattca tcctaaaatc tatgcctaca ccacaccgac agtaaccagt aatgaaggct
     6961 ggattaagat tgggtataca gaacgtgatg tcacacaacg tatcaaggag caaacgcata
     7021 cagctcatat agctacagat gtcttatgga ctggtgatgc agcttataca gaagagcctg
     7081 ataaggggaa aactttcaag gaccatgatt tccaccattt cctttctttc catgatgtag
     7141 aacgtcgtcc caagacggaa tggttctatt ttaatggaac tcctgaaaaa tcaaaaaatc
     7201 tttttgataa gtttgttcag catgatttgt ctggttatca gcctggaaaa ggacaggact
     7261 atactctgcg acaagagcaa gaagaagcag ttgctaagac attagcttat ttccaagaac
     7321 atgctggagg caagtttctc tggaatgcca agccacgctt tggtaaaacc ttgtctacct
     7381 atgacctagc tcgacggatg gaagctgtca atgtcctaat tgtaacaaac cgccctgcca
     7441 ttgctaactc atggtatgat gattttgaaa cattcatagc aggtcaaacg acttacaagt
     7501 ttgtttctga atcagatagc cttaagagtc gtccaatctt gtcacgacaa gaatttcttg
     7561 gtattttagc tgacgatgta agacaacttg cttttatcag tctccaagac ttgaaaggat
     7621 ctgtttattt aggtggagag cacgataaac tcaaatgggt aactgatctg cattgggact
     7681 tgttggttat tgacgaggct catgaaggag ttgatacctt caagactgac caagccttta
     7741 ataagattcg acgaaatttt actctgcatt tgtcaggtac atcatttaaa gcattggcta
     7801 aaggagattt tacagaggaa caaatctaca actggtctta tgctgatgag caggctgcta
     7861 agtattcgtg gtctcttgag caagaagagg aaaatcctta tgaaagcttg cctcagttga
     7921 atctctttac ctatcaaatg tctcagatga ttggcgaaaa gttagaaaaa ggcgctcaga
     7981 tcgatggtga aaatattgac tatgtttttg acttaagtga atttttcgct acagatgata
     8041 aagggaaatt tattcatgag catgatgtca gaaattggtt agatactcta tcaagcaatg
     8101 aaaaatatcc attttcaacc aaagaactcc gtaatgaact caagcatact ttttggcttt
     8161 tagaacgtgt cgcttcggcc aaagcattaa aagccctact agaagaacac ccaatctatg
     8221 aaaactatga gatcgttcta gctgctggtg acggacgtat gtccgaagaa gacgataaag
     8281 tcaaactcaa atccttggac ttggttagaa aagcgatagc agagaatgac aaaaccatta
     8341 ccctatccgt tggtcagctg acgacaggtg tcactatccc tgaatggaca ggtgtattga
     8401 tgttatcaaa tttgaaatca ccagctcttt atatgcaggc cgccttccgt gctcaaaatc
     8461 cttactcatg gagcgataac aaaggaaatc actttcgcaa agaaagagcc tatgtatttg
     8521 actttgcgcc ggaaagaacc ttgattctct ttgatgagtt tgccaacaac ttatcgcttg
     8581 taactgcagc tggtagagga acttcagcta cacgcgaaga aaatattaga gaattattaa
     8641 acttctttcc aattattgcc gaagaccgtg ctggtaagat ggttgaaatt gatgcaaagg
     8701 cagttctaac cactcctcgc cagataaaag ctagagaagt tcttaaacga ggttttatgt
     8761 ccaatctctt atttgataat attagtggta ttttccaagc aagtcaaaca gttttagata
     8821 ttttaaatga gctgccagtt gaaaaggaag ggaaggtaca agatagttct gatttattag
     8881 atttttcaga tgttacagtc gatgatgagg gaaatgcagt agtagaccat gaaattgtag
     8941 ttaatcagca aatgcgactt tttggtgaaa aagtttatgg acttggtgaa tctgttgctg
     9001 agttagtcac aaaagatgag gaacgaactc aaaaacagct ggtcaatgac ttgagtaaga
     9061 ccgtttcttc agtgattgta gaggaattga aagcagatta ttctctaaaa acaagggaaa
     9121 ctgagcaaat taagaaacaa attacagcaa cacttgagaa tgaaattcga aaaaatgata
     9181 tcgaaagaaa aatttctgaa gctcatatca agcaagagtt gcaacagcag ctcaaagaag
     9241 caaatgataa agcgcaaaaa gataagattc aagaagattt ggaaaaacgt ttagaagaaa
     9301 ataaactcat tcataaagaa aaactagaac aaacactcaa aaaagaagtg gaaaaaatgc
     9361 ctgagaaatt tatcgaacag gttgagataa aacgtgtgga acagttgaaa caatcagctc
     9421 aagatgaaat tcgtgaccat ttacgagggt ttgcaagaac aattccaagt tttattatgg
     9481 cttacggtga tcaaactcta acacttgata attttgatgc ctttgttcct gaacatgttt
     9541 tttatgaagt aacagggatt acgattgatc agtttagata tttgcgagat ggtgggcagg
     9601 attttgcagg gcatctcttt gataaagcaa catttgacga agctattcaa gaatttcttc
     9661 gcaagaaaaa ggagttggcg gattatttta aagatcaaaa agaagacatt tttgactata
     9721 ttccaccgca gaagaccaac caaattttca ctcctaaacg agtggtgaaa aggatggtag
     9781 atgatttgga aaaggaaaat ccagggattt ttgatgatcc atctaagact tttattgatt
     9841 tatatatgaa gtcaggcctc tatattgcag aacttgtgaa gcggttatat aatagcaatg
     9901 gcttgaaaga ggcctttcca aatcctgaag aacgcttaaa acatattttg gaaaagcaag
     9961 tttatggatt tgctccgtct gagattatct ataacatttc cactaatttt atatttggta
    10021 atctttctaa agatatcagt aggaagaatt ttgttttagc agataccatt ccagcggcta
    10081 aagaagggag cattcaaaag ttggttgatt cctattttga aaataattaa aaagaaggcc
    10141 gagtcaaaat tctttgaaat cagaaaaaac gcataatatt gagtgctttt gtactgcccc
    10201 ccaaaagtta gacagaaaaa atctaacttt tggggggcag ttcagacaat ccttggtatt
    10261 atgcgtttta ttgtgggaag atgtataatg gattgaaata agatatgaac aaatcgatta
    10321 ggaaaggaaa attgatttat agaaatgttt tagtagtcga tgcgtactgt tatagattca
    10381 acgaactata aaatctgaag aaagcaattt taaccagatc ttagaagcag ttgtgtacta
    10441 ctctaacttc aatagactat atcatataga taaaaaacaa ctccctgatg attcaaggag
    10501 ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt tccatgcttc
    10561 gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt ctgcatcgtt
    10621 caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg gttgaccgat
    10681 aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa gtactgcgtt
    10741 ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac cgtagtatgt
    10801 tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga acaattcaat
    10861 caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt ttacaccagc
    10921 gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca tgatgtaggc
    10981 gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga aacgagctga
    11041 gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga atttccaagt
    11101 tgagtaagtc aaaacgtcaa ctggattagc agcaacaagg aagatacctt tgaaaccaga
    11161 ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta caaggtcaag
    11221 acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt cagcgtctgc
    11281 acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa gggcgtgact
    11341 aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga taattccaag
    11401 ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta cagcaccatc
    11461 accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa acatctcctt
    11521 aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa aaactttgtc
    11581 acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc tgaaatagat
    11641 gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt tattaatgca
    11701 ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt ttatcgacta
    11761 cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct taaaacctgt
    11821 tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca aaccccataa
    11881 aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg gggattcctc
    11941 tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca tgcttgtaga
    12001 tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac gttataccga
    12061 ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa atacagttga
    12121 tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag cgcgttttcc
    12181 aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca atattccacc
    12241 tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc ctgaagtgac
    12301 taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg ctcttgtcat
    12361 ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg tcctacgttc
    12421 tcgtacagag attgaaacga ctaagactgg tcgtgagcgc atcgttgtaa cagaatttcc
    12481 ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc aggaaaaacg
    12541 cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc gatttgttat
    12601 tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca aaatgaccca
    12661 aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac cgaaaatttt
    12721 gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg ttgttcgtcg
    12781 tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag gtctcttgat
    12841 tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa cggatgcgga
    12901 agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc aagctatcct
    12961 tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat ctgagtatga
    13021 tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg aacgtgtttc
    13081 tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata aacgccgtac
    13141 agagttgatg gttggacaga ttttgagtct cgaggatgag gacttgattg aagaatcgga
    13201 tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg acgagttcac
    13261 tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg atgactttgt
    13321 tcgtgagtta gtgtcaacta gcacacatga tcatctgctc ttcttcacaa acaagggacg
    13381 tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca aagggctacc
    13441 agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta tcaatgttga
    13501 gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta ttgtgaagag
    13561 aactagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc tgaatttaaa
    13621 ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata ttatcattgg
    13681 taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta tgagccgtat
    13741 cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg gtgccagctt
    13801 gattactgat caagatgaag ttcttattat cacagaaaaa ggatatggta agcgtacagt
    13861 cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag ctaaaattac
    13921 cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg atttgatgat
    13981 tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac aaacaggacg
    14041 tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag tgactttcac
    14101 aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag aaggtgaagc
    14161 ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct gacaaatatc
    14221 ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca aattcgaaat
    14281 attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa agaaaaatta
    14341 gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc tatctcttcg
    14401 gaagctgttc taacttctca atgggatgct caaaaattac cagttattgg gggaattgca
    14461 attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt taatctcttc
    14521 tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta tagtctagct
    14581 agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc tttagataat
    14641 gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac ttatgaaata
    14701 cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag agatggggtc
    14761 aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat tattgtcaaa
    14821 ggtgatttga aagaaacaaa agattattca caaacatctg atgaaatcct aacagctttc
    14881 aatcaaccat ataaacaatt ttattaatac aaatcagtga aatcatggat ttcactgatt
    14941 ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga ataggacgaa ttgttcagga
    15001 ca
//
LOCUS       DAVLTG010000044        14965 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLTG010000044 DAVLTG010000000
VERSION     DAVLTG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.045"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            88..885
                     /locus_tag="VYN12_001563"
     CDS             88..885
                     /locus_tag="VYN12_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1415922.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1033..2292
                     /locus_tag="VYN12_001564"
                     /pseudo
     CDS             1033..2292
                     /locus_tag="VYN12_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2388..3662
                     /locus_tag="VYN12_001565"
     CDS             2388..3662
                     /locus_tag="VYN12_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1415923.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3672..4550
                     /gene="truB"
                     /locus_tag="VYN12_001566"
     CDS             3672..4550
                     /gene="truB"
                     /locus_tag="VYN12_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1415924.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4811..5113
                     /locus_tag="VYN12_001567"
     CDS             4811..5113
                     /locus_tag="VYN12_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1415925.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5221..5859
                     /gene="udk"
                     /locus_tag="VYN12_001568"
     CDS             5221..5859
                     /gene="udk"
                     /locus_tag="VYN12_001568"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1415926.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5987..7327
                     /locus_tag="VYN12_001569"
     CDS             5987..7327
                     /locus_tag="VYN12_001569"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1415927.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEKGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7305..7517
                     /locus_tag="VYN12_001570"
     CDS             7305..7517
                     /locus_tag="VYN12_001570"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1415928.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7514..8389
                     /locus_tag="VYN12_001571"
     CDS             7514..8389
                     /locus_tag="VYN12_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1415929.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8382..9197
                     /locus_tag="VYN12_001572"
     CDS             8382..9197
                     /locus_tag="VYN12_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1415930.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9190..9621
                     /locus_tag="VYN12_001573"
     CDS             9190..9621
                     /locus_tag="VYN12_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1415931.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9628..11295
                     /gene="recN"
                     /locus_tag="VYN12_001574"
     CDS             9628..11295
                     /gene="recN"
                     /locus_tag="VYN12_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1415932.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11297..12025
                     /locus_tag="VYN12_001575"
     CDS             11297..12025
                     /locus_tag="VYN12_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1415933.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHIGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12104..13927
                     /gene="lepA"
                     /locus_tag="VYN12_001576"
     CDS             12104..13927
                     /gene="lepA"
                     /locus_tag="VYN12_001576"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1415934.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14086..14166)
                     /locus_tag="VYN12_001577"
                     /pseudo
     CDS             complement(14086..14166)
                     /locus_tag="VYN12_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14340..14815
                     /locus_tag="VYN12_001578"
                     /pseudo
     CDS             14340..14815
                     /locus_tag="VYN12_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14853..>14965
                     /locus_tag="VYN12_001579"
     CDS             14853..>14965
                     /locus_tag="VYN12_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1415935.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAV"
BASE COUNT         4475 a         2698 c         3517 g         4275 t
ORIGIN      
        1 tataaacttt tatgaaatac agaaaacgct tcctaaaacc taaagtttgt gatataatta
       61 tcaagaaaaa agatttagga gtttattatg atttcttcag aatttatctc aaagattgaa
      121 tttgcttgca ataagaaaga aagtctttat agtcaaagca aatttaagta tgcgattcgt
      181 tcgatgttcg caggtgcatt tttaaccttc agtactgctg caggtgcagt tggggctgac
      241 ttgattaata aaattgcacc aggtagtgga cgcttcctct ttccattcgt ttttgcttgg
      301 ggcttggcct acattgtttt tttgaatgcc gagttggtca cttcaaacat gatgttcttg
      361 actgctggta gtttcttaaa aaaaatctct tggagaaaaa cagctgagat tttactatac
      421 tgtaccttgt tcaaccttat cggagccttg atagcagggt ggggctttgc tcattcggca
      481 gcctatgcga atctgacaca cgatagtttc atctcaggtg ttgttgagat gaagttaggc
      541 cgctcaaatg aattggtctt gcttgaggcg attttggcaa atattttcgt aaatattgcg
      601 attctgtcat ttattttggt caaagatggt ggtgccaaac tttggcttgt gttgtcagct
      661 atttacatgt ttgtattctt aacaaacgag cacattgcgg cgaactttgc ttctttcgcg
      721 attgtgaaat tcagtgttgc tgcggattca attgccaact tcggtgttgg aaatatgctt
      781 cgccactggg gtgtgacttt catcggaaac tttatcggag gaggcctctt gatgggtctt
      841 ccatatgcct tcctcaataa aaacgaagat acttatgtag attaagaaaa tgagcacgat
      901 tgagtcgtgc ttttttcatt ttcaaaataa ggtaatagct atttcttata tcaaaatata
      961 gaaaactgat atttgtaaac tataactcaa ggtgctacaa tatccttaat aaaatgatat
     1021 ggaggtcacc ttatgacttg tgattttaaa tctgaaactc tacaactaca tgctggtcaa
     1081 gttgtggctc cagctactaa gtctcgtgca gtgccgattt atcaaacaac attttttgtt
     1141 tttgatgaca cgtaggaagg tgccgatctg tttgccttga ggaaaccagg gaacatttat
     1201 actcgtatca ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc gctagcaaca
     1261 gcatcaggta tgactgcagt gacttatacg attttggcgc ttgcccatgc tggtgaccat
     1321 gtagtggctg cttcgactat ttacggtgga accttcaatc ttttgaaaga accccttcct
     1381 cgttatggta tcacaacaac ctttgtcgat gttgataatt tggaggaagt agaagcagct
     1441 atcaaagaca ataccaagct tgtcttgatt gaaaccttgg gtaacccctt gattaatatt
     1501 ccagacctgg aaaaactggc agagattgct cataaacatc aaatcccact tgtgtcagac
     1561 aatacttttg caatacctta tttgattaac gtcttctctc atggcgttga cattgccatt
     1621 cactctgcga ctaagtttat cggtgggcat ggtacaacta ttggaggaat aattgtcgat
     1681 agtggtcgtt ttgactggac ggcttcaggg aaattccctc aatttgttga cgagggttca
     1741 agctgccaca atttgagcta tattcgtgat gtgggtgcag caacctttat tatagctgtt
     1801 cgagttcaat tgcttcgtga tacaggtgca gtcttgtcac cattcaatgc tttcctcttg
     1861 ctacaaagac ttgaaactct ttcacttcgt gtggaacgcc atgtacaaaa tgctgagaca
     1921 attgttgatt ttcttgtcaa ccatcctaag gtagaaaagg taaattatcc aaaacttgca
     1981 gatagtcctt atcatgcctt ggctgagaaa tacttgccaa aaggtgtcgg ttcaatcttt
     2041 accttccacg tcaaaggtga cgaggaagaa gcacgcaagg tcattgataa tttagaaatc
     2101 ttttctgacc ttgcaaacgc ggcagatgct aaatcgcttg ttgtccatcc agcaacaacc
     2161 actcacggtc aattgtcaga aaaagaccta gaagcagcag gtgtcacacc aaaccaaatt
     2221 cgtctgtcaa tcggtcttga aaatgtagaa gatttgattg aagacttacg cttggccttg
     2281 gaaaaaattt aaagtaaaag aagataaaca gtgggttttg actcactgtt tttgattttc
     2341 cctcaggcat gatataatgg ttacagaagt ctagaaagag gaatgtaatg aacgaaatca
     2401 aatgtcccaa ctgtggggaa gtctttacag taaatgaaag ccagtatgct gaacttttgt
     2461 cccaagtgag aacggcagag tttgataagg aactacacga taggatgagg caggaactgg
     2521 ccttggctga gcaaaaggct atgaatgagc aacagactaa actggctcag aaggatcaag
     2581 aaattgcgca attgcagagt caaatccaaa actttgatac agaaaaagaa ttggccaaga
     2641 aagaagttga acagacaagc catcaggcct tattggctaa ggacaaggaa gtacaggctt
     2701 tggagaacca attggccact ttgcgtttgg agcatgaaaa tcaactgcaa aagacccttt
     2761 ctgacctaga aaaagaacgc aatcaggtca aaaatcagct cctactgcaa gaaaaggaaa
     2821 atgagttgtc tttggcttct gttaagcaaa actacgaagc ccagctcaaa gcagccagtg
     2881 aacaagtcga gttttataag aattttaagg ctcaacaatc tacaaaagcg attggggaaa
     2941 gcctagaaca gtatgcagag agtgagttta acaaggtccg tagtttcgcc tttccaaatg
     3001 cttactttga gaaggataac aaggtctctt cgcgtgggtc taaaggggac tttatcttcc
     3061 gtgagtgtga tgaaaatgga gttgaaatca tttctatcat gtttgagatg aaaaacgaag
     3121 cggacggaac agagaagaag cacaagaatg cagattttta caaggaattg gacaaggacc
     3181 gtcgggagaa gaactgtgag tatgccgttt tggtgaccat gcttgaggcc gataatgact
     3241 actttaacac agggattgtt gacgtcagcc acgagtatga aaaaatgtat gttgttcgtc
     3301 ctcaattctt tatccagttg attggtctct tacgtaatgc ggcgctaaat tccctaaaat
     3361 acaagcagga gttggccttg gttcgcgagc aaaatattga cattacgcat tttgaggaag
     3421 atttggatgc ctttaagcta gcttttgcta agaactataa ttcagcttcg actaactttg
     3481 gaaaagctat tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt aagaaattcc
     3541 tgactacatc tgaaaaccaa ctccgtctag ctaacaacaa attggaagat gtctctgtta
     3601 aaaaattgac ccggaaaaat ccaacaatga aagcgaagtt cgaagcactg aagggggagt
     3661 agaaagcaaa aatgaacggt attattaact taaaaaagga agcaggaatg acctcgcatg
     3721 atgcggtttt taaactgcgt aagattttgg gaaccaagaa aattggtcat ggtggaacct
     3781 tggatccgga tgtggtgggt gttttgccga ttgcggttgg caaggcgaca cgcatggtcg
     3841 agtttatgca ggacgagggt aagatctatg agggggaaat cactctgggc tattccacga
     3901 cgactgagga tgctagtggg gaagtggtcg cagaaacccc tgttttgtct ctcttggatg
     3961 aaaagcttgt tgatgaagcg attgctagct tgactgggcc tattactcag attcccccta
     4021 tgtattcggc agttaaggtt aatggtcgca agctctatga gtatgcgcgt gctggtcagg
     4081 aagtggagcg tccagaacgt caggtgacca tttatcaatt tgagcgaaca agtccgattt
     4141 cttatgatgg ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa gggacgtaca
     4201 tccgtacttt gtcagttgat ttgggtgaaa agcttggtta tgcggctcat atgtcccatt
     4261 tgactcgtac tagtgctgct ggcttacaat tagaagacgc tcttgccttg gaggaaattg
     4321 ctgaaaaagt agaggctggg caattagatt ttctccatcc tttagagatt gggacaggtg
     4381 accttgtcaa agttttccta actccagaag aggctacaga agttcgcttt ggtcgtttta
     4441 ttgagctaga ccaaacggac aaagaattgg ctgcctttga agatgataaa ttgttagcca
     4501 ttctagaaaa acggggcaat ctctataagc caaggaaggt ttttagctag atcgtttagg
     4561 aataaaaatc gggtgataga taataattgc ttgataaaac cccatactaa tagtagaatg
     4621 gttttgggaa ttataatatt ccaattgttg cgagttgtag gtactcaaat aatctattag
     4681 gtactcaaat aatctatata gaaatttaga ggtgtgaaat gaagcaattt aaaattcttt
     4741 cagataaata tttagagtcc attacaggtt ctggtgggaa cttaggccca ggatttggtg
     4801 tgataattcc atgatgcgaa atgagtttcg agaaagggtg gagcaacttc ttcaacaaaa
     4861 agaaataaat gaaaatagtg agttgagtca cctgtttcgt cttgctatac aaaatttaga
     4921 cagaaatgaa aaataccaaa cggtcatggc caatttgagt caagggttgt cactttacct
     4981 catgacgcat cattaccagg cacctaagtc tgtcattgat tttggtttat ggattgccaa
     5041 agctcctagc caggaaagag ggagactggc tttcttgcag atgcttgctc aaaccctaca
     5101 gggctttcgt taaaactgtc gaacatcaga gggaagactc tggtgttttt tgctgatgag
     5161 actataaatt ttgtaaaaaa tgtgatagaa tagacgacgg ataaaataac ggaggatagc
     5221 atgcaaaata gaccaatcat tattggagtg acaggtggtt ctggtggtgg taaaactagt
     5281 gtttcaagag ccattttatc gcattttcct gatgaaaaga tttccatgat tgagcatgat
     5341 tcatactaca aggatcagtc tcatttgacc tttgaagagc gtgtcaaaac caactatgac
     5401 catccttttg cctttgatac agacttgatg atcgagcaga ttaaggaatt gttggcaggg
     5461 cgtccggtgg acatcccgac ctacgactat acagagcata cacggagtag caagacctat
     5521 cgtcaggagc ctcaagatgt ctttatcgtt gagggcattt tggtcttgga ggacaagcgt
     5581 ctgcgcgatt tgatggatat caagattttt gtggatacgg atgacgatgt gcgcattatt
     5641 cgtcgtatca agcgtgatat ggaggagcgt ggccgtagcc ttgatagcgt tattaaccag
     5701 tacttaggtg tggtcaaacc aatgtaccac cagtttatcg agtcaactaa gcgttatgct
     5761 gatatcgtca ttcctgaagg ggttagcaat accgtggcta tcgacctgtt gacgaccaag
     5821 attgcaaaga ttttggaaga agctcgaaac agcaaataat cacatgtgga ggccttgcct
     5881 cctttttcta tttttccctc ataatggtac ataaatggag atttttaggc atatttttgg
     5941 tataataata cccatgaaag agcaagtaaa tgaatagtag gtggagatgg aaaagtattt
     6001 atcggtaaca actttgacca agtatctgaa aatgaaattc gataaagacc catacttgga
     6061 acgggtctat ttaactggtc aagtttccaa ctttcgtaaa cgacctactc accaatattt
     6121 ctccctaaag gatgaccatg cagttattca agcgaccatc tggtctggga tttatcagaa
     6181 attagggttt gacctggaag aaggaatgaa gatcaatgtg attgggcgtg tacaggtcta
     6241 tgaaccaagt ggtagctact ccatcatcat tgaaaaagct gagcctgatg gggttggggc
     6301 gcttgcgatt cagtttgaac aacttaagaa aaaattgaca gaaaaaggcc tgtttcaaga
     6361 acgcttcaag caagctctac cccaattttc taagagaatt ggggtagtaa ccagccgtag
     6421 tggagccgtt attcgagata ttatcacgac cgtcagcagg cgattcccag gtgttgacat
     6481 ccttctttat cctaccaagg ttcaaggtga aggggctgcg gaggaaattg ctagaaatat
     6541 tgcgcgtgct aatcaacggg acgatttgga tttgctcatt attggtcgtg gaggtggttc
     6601 tattgaggat ctctgggcct ttaacgaaga aattgtggta cgagctattt ttgaatctcg
     6661 tttgccagtt atctctagtg tggggcatga gacggatgtg accttggcag attttgtggc
     6721 agatcgacgc gctgcaacgc caacagcggc ggctgaactg gcaacacctg tgaccaagtt
     6781 ggatgtatta actcatttgc aaaatcagga aaaacggatg gcaacggcag tccgaaatgt
     6841 tctatctaag aaacaagagg ctttgaaaaa atgcagtcag tctgttatct ttagacaacc
     6901 tgagcgcttg tatgacggtt atttgcaacg cttggaccaa ctgcaactgc gtttgaaaca
     6961 aagtttgcga actcggattt ctgataacaa acaattagtt caagcaagaa ctcatcaatt
     7021 agtacaatta tcacctgtta ccaaaatcca acgctatcaa gaccgtttag gacagttgga
     7081 caagctctta ggtagccaaa tggcgttagt ttatgacgcc aaggttgctg aggccaagcg
     7141 actttcggaa gctttgctca tgttggatac tagccgaatc gtggcgcgtg gttatgctat
     7201 tgtcaaaaaa gaagagtcca ttgtagattc ggttgagagt ttgaagaaaa aagaccaagt
     7261 aacgcttttg atgcgagatg gtcaagtaga attagaggtt aaagatgtca aaacaaaaga
     7321 aatttgagga aaatctagca gaactggaaa ccattgtcca aagtttggaa aatggtgaaa
     7381 ttgctctgga agatgcgatt actgcctttc aaaagggcat ggtcttgtca aaagagctcc
     7441 aagctacgct ggacaaggct gaaaagacct tggtcaaggt catgcaagaa gacggaacag
     7501 aaagtgattt tgaatgaaaa agcaagaaaa attagctctt gtcgagtcgg ctttggaaga
     7561 tttttatgga gaccagcagt ttgcctctag tttacgggag tctgttctct attctattca
     7621 tgctggtggc aagcgtattc ggccttttct cttgttagaa gttctggaag ccttgcaggt
     7681 taccatcaaa cctgctcacg cgcaggtagc tactgccttg gagatgattc atacagggag
     7741 cttgattcac gatgaccttc ctgctatgga tgatgacgat tatcgaagag ggcggttaac
     7801 caatcacaag aaattcggtg aagctatggc cattttggct ggagatgcct tattcttaga
     7861 cccatatgcc ttgattgcgc aggcagattt gccaagtcag attaaggtgg acttgattgc
     7921 caacttatcc cttgcttcag gtagtctggg tatggtggca gggcaagttt tggatatgga
     7981 gggcgaacac cagcacttgt ctttggaaga acttcagatt attcatgcca ataagactgg
     8041 gaagttacta gcctatccct tccaagcggc agctattata gctgaattgt cacctgaaat
     8101 gcaggtgaag ctgaaaactg tgggtgaatt gattggactt gcttttcaag tcagagatga
     8161 tgtactggat gtgacagcta gttttgagga aatcggcaag acacctcaaa aggatctgca
     8221 ggcagaaaaa tcaacctatc ctgccctgtt gggcttggaa gagtccattg ccttttgtaa
     8281 ccaaaccctg gatcaagcta atgaaaaatt agaagaaatt gcccagcagc ttccctttga
     8341 aacagaatcg attgtaagtg tagtagaaag tttgagaatc aatggctaag gaaagagtgg
     8401 atgtactagc ttataaacag gggttgtttg aaacgagaga gcaggccaag cgaggtgtaa
     8461 tggctggcct agtcgtagca gtccttaatg gagaacggtt tgacaagcca ggagagaaaa
     8521 ttccagatga caccgaatta aaactcaagg gagagaaact caagtatgtc agccgtggtg
     8581 gtttgaaact ggaaaaggcc ttgcaggtct ttgatttgtc ggtggatggc gcgactacga
     8641 ttgatatcgg ggcctctact ggaggtttta ccgatgtcat gctacagaat agtgccaagt
     8701 tggtctttgc agtcgatgtt ggtaccaatc agttggcttg gaaattacgc caagacccac
     8761 gagttgttag catggagcag ttcaatttcc gctatgctga aaagactgat ttcgagcagg
     8821 agccgagctt tgccagtatt gatgtgagtt tcatttccct tagtctgatt ttgccagcct
     8881 tgcaccgtgt cttggctgat caaggtcagg tggtagcact tgtcaaacct cagtttgagg
     8941 caggacgtga gcagattggg aaaaatggaa ttattcgaga tgctaagatt catcagaatg
     9001 tccttgaatc tgtaacagct atggcagtag aggcaggttt ttcagtcctt ggcttggact
     9061 tttctcccat ccaaggtgga catggaaata ttgaattttt agcgtatttg aaaaaagaaa
     9121 agtcagcaag caatcagatt tttgctgaga ttaaagaagc agtagagagg gcgcatagtc
     9181 aatttaaaaa tgaataaaaa agagagactt gaaaaaatta gaagattggt gacagattat
     9241 caaatcggca cgcaagaaga aattgtagaa catttgaaag aagcaggtat cactgccact
     9301 caggcgacgg tatcccgaga tatcaaagag ttaggtattg tcaaaattcc tttgagagac
     9361 aacacctatg tctacgaatt accaaaatca atcgtaaaaa gtctgcaact ggctgaagac
     9421 aatatcgaat cggctgaatt gatggataag atgatcaatc tccaagttat tccaggaaat
     9481 acggcttttg taaaagctca gttaatcgat acttttgcag acaagatttt tagttgtttg
     9541 actgatgata gctcgatttt agtcattgcc agaagtggaa gtctagcaga ggaaatcttt
     9601 gaacaagtaa aaaattggta ggtctatatg ttacttgaaa tttcgataaa aaactttgcc
     9661 attattgagg ctatttccct caattttgaa aaggggatga ctgtcctgac tggtgaaacg
     9721 ggtgcaggga agtcgattat cattgatgcc atgaatatga tgttgggagc tcgtgcgacg
     9781 acagatgtta ttcgtcatgg tgcaccaaag gcagagattg aggggctttt ctcagttgag
     9841 aatagtcgtc ttttacagga aatttttgat gagcaaggtt tagaattagg tgatgaaatt
     9901 atcatccgtc gggaaatctt gcaaaatggt cgtagtatca gccgtgtaaa tggtcagatg
     9961 gttaatctgt ctgttttgcg agctattggg caacatcttg tagatattca tggtcagcat
    10021 gaccatgagg agttaatgcg tccccaactg catatccaga tgttggatga atttggtgat
    10081 gccgcttttt gggacttgaa agaaacctat caaacgagtt ttgatgccta tcggaaaatg
    10141 cgcaagcagg ttctggaagt caagaaaaac caacaggaac acaaggaacg tatcgaaatg
    10201 ttggaatttc aaatggcaga gattgaggca gcaaacttgc aggctggaga agacttggct
    10261 ctcaatcaag agcgagataa actcctcaac cacaaaaata ttgcggatac actgaccaat
    10321 gcctacagta tgttggacaa tgaagatttt tcaagtctgg ccaatgttcg ttcagctatg
    10381 aatgacatgg aaagtgtcga agagtatgat cctgaatacc gtgaaatttc aagctctctg
    10441 tctgagacct actatgtttt agaagacatt agcaaacgtt tggaagctat cattgaggac
    10501 cttgattttg atggcaatcg cctgatgcag gttgagaatc gtttggacct ccttcatact
    10561 attactcgta agtatggtgg gactgttgat gatgttttgc tttattttgc caagattacg
    10621 gaagaataca atctcttgac aggcaataat ctttcgtctg aggacatgga agcagagctt
    10681 aagaagttgg aagtcaatct tgtcaatttg gcaggtcaac ttgcttctgc tcgtcataat
    10741 ttggctcagc aactcgaagc tgagattaaa caagaactgc aagatcttta tatggaaaaa
    10801 gcccagtttc aggttcattt tagtaaggga aaattcagtc gtgggggaaa tgaaatggtt
    10861 gagttttata tttcaaccaa ccctggagaa gactttaaac ccttggttaa ggttgcttct
    10921 ggaggggaat tatctcgtct catgttagcc attaagtctg ccttttcacg taaagaaggc
    10981 aagactagca ttgtctttga tgaggtggat acgggagttt caggtcgtgt tgctcaagct
    11041 attgctcaga aaattcataa aattggtcag catggtcagg ttttggctat ctcccatttg
    11101 ccacaagtaa ttgcgattgc agattatcaa ttctttattg agaagattag taatgaccat
    11161 tcaacggttt cgactgttcg tctcttgaca gtcgaagagc gagtggagga agttgccaag
    11221 atgttggcag gtgatgatgt gacagaagca gccctgacgc aagccagaga attgttgaga
    11281 aacagggaga aataagatga cagattatta tgtaattgga gatgttcacg gaaaagctgg
    11341 gatgctggaa gaccttctta aaacctggga tggtcagacc cagttgctct ttctaggtga
    11401 tttgattgac agaggtgagg atagtcaccg tgttcttgaa atggtcaagg acttggtgga
    11461 caatcaaggg gctatctgtt tgtctggaaa ccacgagtat atgtttttga cttggctaga
    11521 tgacccagaa gaaagttatg accattatcg tcgcaatggt ggagatacaa ccattaactc
    11581 tatcctaggt cgtcccttgg atgcaccagt tgatggagta gaagatgcca agcgggttgc
    11641 cgctgaagcg tcagacttgg tcgaattcat tcgtcaaatg ccatttgtag tagagacaga
    11701 caagtatata tttgttcacg caggtattga tttgactttg gacgactggc atgaaacaac
    11761 agattataaa aaagtatggc ttagaaaacc attccacgga gctgaaaatc atattggaaa
    11821 aaccattgtc ttcggtcata caccggtcta tggtttgtta cagcaagaac gcggtacatc
    11881 tgagctttgg actacagaag atggcaagat tggaatggat ggaggagctg tttatggtgg
    11941 tgtccttcac gggattgtct ttacagacca aggaatgaca gaacaccact ttatcgaaaa
    12001 tgacggcttt gtcgctgaag attagtactc ctagcagggt atggtcttgt caaaatatca
    12061 aaaacaattt ataataaata gataccctga aaggaagaga atcatgaact tagaagaatt
    12121 gaaaaaacga caggggaaga tccgtaactt ctctattatc gcccatattg accacgggaa
    12181 atcaactcta gcagaccgca ttttggaaaa aacagagacg gtttcaagtc gtgaaatgca
    12241 ggcccagctt ttggatagca tggatctaga gcgggaacgt ggaattacta ttaagttgaa
    12301 tgccatcgag ttgaattaca ctgcaaaaga tggggaaact tatattttcc acttgattga
    12361 cacaccaggg cacgttgact ttacctatga agtttcacgt tcgctagctg cctgtgaggg
    12421 tgctattttg gtggtcgatg cggctcaagg aattgaggct caaactcttg ccaacgttta
    12481 tctggctttg gataatgatt tggaaatcat gcctatcatt aataaaattg acctgccggc
    12541 tgcagatccg gagagcgtgc gtacagagat tgaagatgtg attggtttgg atgccagtga
    12601 agcagttttg gcttctgcca aggctggtat tgggattgaa gaaatcctcg agcaaattgt
    12661 agaaaaagta ccagcaccaa cgggtgatgt gacggcgcca cttaaggcct tgattttcga
    12721 ctctgtttac gatgcttacc gtggggttat cctccaagtg cgtgtcatgg acggagtggt
    12781 caaacctggt gataagattc agctcatgag caatagtaag acctttgatg tggccgaagt
    12841 cggtattttt acaccaaaag cggttggtcg tgatttcctt gcgactggtg atgttggtta
    12901 cattgcggcg tctatcaaga cggttcagga tactcgtgtg ggtgataccg ttaccttggc
    12961 aaccaatcct gcggcagaac cattacatgg ttataagcag atgaatccta tggtctttgc
    13021 gggtctctac ccaatcgaat caaacaagta caatgacctg cgtgaagcgc ttgaaaaatt
    13081 gcaactgaat gatgctagtc ttcagtttga accagaaaca tctcaggcac ttggatttgg
    13141 tttccgttgt ggatttcttg gacttctcca tatggatgtt atccaggaac gtttagagcg
    13201 tgagttcaat attgatctca tcatgacagc tccgtctgtt atttacaaag ttaatttgac
    13261 cgacggtgag tctatggatg tgtctaaccc atctgagttt ccagacccaa ctaagattgc
    13321 gaccattgaa gagccttatg tcaaggcgca aatcatggta ccacaggagt tcgtcggagc
    13381 agtaatggag ctagctcagc gtaagcgtgg ggactttgtg actatggact atattgatga
    13441 taaccgtgtc aatgttatct atcaaattcc tcttgctgaa atcgtctttg acttctttga
    13501 taaacttaag tcttcgacac gtggttatgc aagttttgac tacgaattgt cagaatatcg
    13561 cccatctaag ctagtgaaaa tggatatcct tctcaacgga gacaaggtgg atgccctcag
    13621 ctttatcgtt cataaggact ttgcttatga acgtgggaaa ctcatcgttg ataagctcaa
    13681 gaaaatcatc cctcgccaac aatttgaggt tccaatccaa gcggctattg gacacaagat
    13741 tgtcgctcgt actgatatca aggcccttcg taagaacgta cttgctaaat gttatggtgg
    13801 tgacgtttct cgtaagcgta aactccttga aaaacaaaaa gctggtaaga aacgcatgaa
    13861 atccatcgga tcagttgaag ttccgcaaga agccttcctc agcgtcttga gtatggatga
    13921 agaataagtt atcagaaatg cctttccttg ttcacaggaa atttatataa gaatcaatag
    13981 taaagcaggc ttagatggtc tgctttttta gtttttatac tcttcgaaaa tctcttcaaa
    14041 ccacgtcagc gtcgccttac cgtatgtatg gttactgact tcgtcagttt catctacaac
    14101 ctcaaaactg tgttttgagt aacctgcggc tagcttccta gtttgctctt tgattttcat
    14161 tgagtattag aacagaaaaa tgcttggagt atttgtttgt gtgtttattt ttatataaca
    14221 aactataaac acaacaaaaa tataaaaaaa gagacaaaaa agaacagaaa gtaattaaca
    14281 acgatttcat atagtgttat acttatagca taaagttaat ggaaagaagg gaaaacctta
    14341 tggtattaga ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg gataatcaag
    14401 aataactctt tgatcaggta gcaagcttgt tggaggaacg agaaattgta actccaactt
    14461 atcgtgaagc tttgatcacg cgtgaaaagt catttccaac tggtttagat atggaatttc
    14521 taggaaagga cttgcaaatg taatgattcc tcacacagat attgttcata atctagctga
    14581 gaaagtggtg gttgttcgat tagaaaaacc agtaactttt cacaatatga tagctcctga
    14641 taaggaagta gaagtatctc tactcttctt tatcattaac aattcaagtt caagtcaaac
    14701 gaacattctg gctcagttga tggacttttt cacaggaaat ggtcatcttg aagacctatc
    14761 aaaaatttct gaaccagaaa aactttatgc ttatatagat gaagcaatcg cttaatcttg
    14821 tctattaaaa aataaaatcg gaggaagtct atatgattaa aattcttgct gcctgcggtg
    14881 caggtgttaa ctcaagtcac caaattaaaa gtgctctaga agaagaactt tcaaaccgtg
    14941 gttacgatgt tcactgtgat gcagt
//
LOCUS       DAVLTG010000045        14717 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLTG010000045 DAVLTG010000000
VERSION     DAVLTG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.046"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(105..854)
                     /locus_tag="VYN12_001580"
     CDS             complement(105..854)
                     /locus_tag="VYN12_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1415936.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDCSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            987..3323
                     /locus_tag="VYN12_001581"
     CDS             987..3323
                     /locus_tag="VYN12_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1415937.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKLINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            3425..4102
                     /locus_tag="VYN12_001582"
     CDS             3425..4102
                     /locus_tag="VYN12_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1415938.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            4089..4886
                     /locus_tag="VYN12_001583"
     CDS             4089..4886
                     /locus_tag="VYN12_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1415939.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            4903..6006
                     /locus_tag="VYN12_001584"
     CDS             4903..6006
                     /locus_tag="VYN12_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1415940.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            6013..6204
                     /locus_tag="VYN12_001585"
     CDS             6013..6204
                     /locus_tag="VYN12_001585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415941.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            6307..7326
                     /gene="galE"
                     /locus_tag="VYN12_001586"
     CDS             6307..7326
                     /gene="galE"
                     /locus_tag="VYN12_001586"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1415942.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            7328..8293
                     /locus_tag="VYN12_001587"
     CDS             7328..8293
                     /locus_tag="VYN12_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1415943.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(8344..8550)
                     /locus_tag="VYN12_001588"
     CDS             complement(8344..8550)
                     /locus_tag="VYN12_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1415944.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            8602..9078
                     /locus_tag="VYN12_001589"
     CDS             8602..9078
                     /locus_tag="VYN12_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1415945.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            9087..9758
                     /locus_tag="VYN12_001590"
     CDS             9087..9758
                     /locus_tag="VYN12_001590"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1415946.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            9889..10227
                     /locus_tag="VYN12_001591"
     CDS             9889..10227
                     /locus_tag="VYN12_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1415947.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            10230..10859
                     /locus_tag="VYN12_001592"
     CDS             10230..10859
                     /locus_tag="VYN12_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1415948.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            11099..12250
                     /locus_tag="VYN12_001593"
     CDS             11099..12250
                     /locus_tag="VYN12_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1415949.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            12563..13312
                     /gene="truA"
                     /locus_tag="VYN12_001594"
     CDS             12563..13312
                     /gene="truA"
                     /locus_tag="VYN12_001594"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1415950.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            13302..14075
                     /locus_tag="VYN12_001595"
     CDS             13302..14075
                     /locus_tag="VYN12_001595"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1415951.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            14053..14514
                     /locus_tag="VYN12_001596"
     CDS             14053..14514
                     /locus_tag="VYN12_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1415952.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         4092 a         2834 c         3435 g         4356 t
ORIGIN      
        1 tcaaatcgat ttctaaaaat gttttagaag tagaggtgta ctattctagt tccaatctac
       61 tatataaatg aaaaccttag ctgtttggcc aaggttcatt tcttctatgc aagttcttct
      121 cttttcttat ctgggttcca gatgaagctt gcgataaagc taaagatgat ggttaggata
      181 gcgaggataa tagcaaggat gagggcaggg atgcggataa accaccagag tggatttggt
      241 tttttatcat tgtgccattg tttcgtttct tcgtccagac gttggaattc tgtttgaata
      301 cgattggcga ctgtttcaat gccttcatca ttcattttct tgatatctga gatatcgatt
      361 ggatttccaa agttcatatc gacacgttca cggctaatca agcccttcaa agtcatggga
      421 ccggtgtagg taaccggcat gatacggacc ttggccattt tggcaatcag tgctgcgccc
      481 cccttgacat cgtttgagtg gcggctacca cttggaaaca tgatgagaga gcagtcactt
      541 tttttgagaa cgttgatagg atatttgatg gctgaggcgc tgggattttc acggtcgatg
      601 ggaaaggcgc cacacatacg aatccaccaa ccaaagatac ggttggtaaa gagttctttt
      661 tttgccataa agatgaactg ttttggcttg gtcgcaaagg ccatataaac aggatcccac
      721 caggtacggt gaggcgcaac taaaatataa ttttcatctt gattaggaat tttatcagta
      781 ttatgatagt gagcattgcc attgatggac cataagagca atacaactaa tccacgcaaa
      841 taagtataaa acatgcgatc tccttcaatt gttttcttgt tattattata ccttatcaaa
      901 ggagggctgg caaacttttc ccttgactag atgcatattt gggatgaaat tagaattctg
      961 ttaaaaaaaa tgatataata gaatttatgg ataaaaataa gattatggga ttaacccaaa
     1021 gagaagtcaa ggaaagacag gctgagggtt tggtcaatga ctttaccgca tcagccagta
     1081 ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct ttttaacgct ttgaactttg
     1141 ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa tctggtcttc tttgctgtta
     1201 tctgctttaa cgctttttct gggattgtga ccgagctacg agccaaacac atggtggaca
     1261 agctcaatct catgaccaag gaaaaggtca aaaccatccg tgatggtcag gaagttgctc
     1321 ttaatcctga agaattagtg ctaggagatg tcattcgttt gtctgcagga gagcagattc
     1381 ctagtgatgc cttggttttg gaaggctttg cggaagtcaa tgaagccatg ttaacgggag
     1441 aaagtgattt ggtgcaaaag gaagttgacg gcttactttt gtcaggaagt ttcctagcca
     1501 gtgggtcagt tttatctcaa gttcaccatg tcggtgcaga caactatgct gccaaactca
     1561 tgcttgaggc taagaccgtt aaactcatca actcccgtat catgaaatcg ctggacaagt
     1621 tggctggttt tactgggaag attatcattc cctttggtct ggctctcttg ctggaagcct
     1681 tgcttttaaa aggcctgcct ctcaagtcat ctgttgtaaa ctcgtcgaca gctcttttgg
     1741 gaatgttgcc taagggaatt gcccttttga ccattacttc gctcttgact gcagtgatta
     1801 agctaggttt gaaaaaggtc ttggtgcagg agatgtactc tgttgagacc ttggcgcgcg
     1861 tggatatgct ctgtctggac aagacgggta ccatcaccca aggaaagatg caggtggagg
     1921 ctgttcttcc actgacggaa acttatggtg aagaggctgt tgccagcatc ctgaccagct
     1981 atatggccca tagtgaggat aaaaatccaa cagctcaagc cattcgccag cgttttgtgg
     2041 gagatgttgc ttatcctatg atttccaatc ttcccttctc gagcgaccgc aagtgggggg
     2101 ctatggagtt agaaggtttg ggaatagttt tcttaggggc acctgagatg ttgctggatt
     2161 ctgaagtccc agaagccagg gaggccttgg agagaggatc acgtgtcttg gtcttagctc
     2221 tcagtcagga gaaattagac catcacaaac cacagaaacc atctgatatt caggctctag
     2281 ccttgctgga aatcttggac cccattcgag agggagcagc agagacgctg gactatctcc
     2341 gttctcagga ggtgggactc aagattatct ctggtgacaa tccagttacg gtgtccagca
     2401 ttgcccagaa ggctggtttt gcggactatc acaactatgt agattgctca aaaatcaccg
     2461 atgaggaatt gatggccatg gcggaggaga cagcgatttt cggacgtgtt tcccctcatc
     2521 aaaagaaact catcatccaa acgttgaaaa aagcgggtca tacaacggct atgacagggg
     2581 acggggttaa tgatatcttg gcccttcgtg aggcggattg ttctatcgtg atggcggagg
     2641 gggatccagc aacccgtcag attgccaatc tggttctctt aaactcagac tttaatgatg
     2701 ttcctgagat tctcttcgag ggtcgtcgcg tggtcaataa cattgcccac atcgccccga
     2761 ttttcttgat aaagaccatc tattccttcc tgttagcagt catctgtatt gccagtgctt
     2821 tactaggtcg gtcagagtgg attttgattt tccccttcat tccgatccag attaccatga
     2881 ttgaccagtt tgtggaaggt ttcccaccat tcgttttgac ttttgagcga aatatcaaac
     2941 ctgtcgagcc aaacttcctc agaagatcca tgcttcgtgc cctaccaagt gccctcatgg
     3001 tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag tcaaggttgg tctgagttag
     3061 aaatctcaac tctcctctat tatctcttgg ggtcaattgg tttcttatcc gtatttagag
     3121 cctgcatgcc attcactcta tggcgagtcc tcttgattgt ctggtcagta ggaggcttcc
     3181 tagccacagc tctcttccca agaatccaaa aactgcttga aatttcaacc ttgacagaac
     3241 aaacgttgcc tgtttatggt gtcatgatgt tggtctttac agtgattttc atcctgacta
     3301 gtcgctatca agctagaaaa taaagaaaga ctgcaatctg tggattgcag tttttttagg
     3361 tacaagattg ccagccgaaa tgtggtataa taagaggtaa tagagttttg gaaagtgaga
     3421 gaagatgatt tcaaagagat tagaattggt agcttccttt gtgtcacagg gggctatttt
     3481 actagatgtg ggaagtgacc atgcttatct gcctatcgag ttggttgaga gaggccaaat
     3541 caaaagcgct attgcaggtg aggtggtgga aggtccctat cagtctgcgg ttaaaaatgt
     3601 tgaggctcac ggcctaaagg agaaaatcca agtccgttta gccaatggct tggcagcttt
     3661 tgaagagact gaccaagtgt ctgtcattac cattgctggc atgggtggtc gtttgattgc
     3721 taggatttta gaagaaggtt tggggaagtt agctaatgta gaacgtttga tcctccagcc
     3781 caataatcgt gaagacgact tgcgtatctg gctacaggat catggattcc agattgtagc
     3841 agaaagcatc ttagaagaag ctggaaagtt ttatgagatt ttggtggtgg aagcaggaca
     3901 aatgaagcta tcagccagtg atgttcgctt tggtcccttc ttgtccaaag aagtcagtcc
     3961 agtatttgtc caaaaatggc aaaaagaagc tgagaagcta gagttcgccc tcggacaaat
     4021 cccagaaaaa aatctggaag aacgtcaagt tctagtagat aagattcaag ctatcaagga
     4081 ggtgctccat gttagcaagt gaagtgatcc aagcttatga agccttttgc cctcaggaat
     4141 tttctatgga gggagacagc tgtggtctgc aaattggcac tttagacaag ggtatccaaa
     4201 gggtcatggt ggctctcgat attcgtgaag agacggtggc tgaagccatt gaaaagggtg
     4261 tagacttgat tatcgtcaag cacgcgccta tctttcgtcc tatcaaggac ttgcttgcca
     4321 gccgtccgca aaatcagatt tacatcgacc tgattaagca tgacatcgca gtttatgtca
     4381 gccataccaa tattgatatc gttgaaaatg ggctcaatga ctggttttgt cagatgctag
     4441 gaatcgagga gacgacttat ctgcaggaaa caggtccaga acgtggaatt ggacgtattg
     4501 ggaatattca gcctcagaca ttttgggaat tggcccaaca ggtcaagcaa gtctttgacc
     4561 tagatagcct tcgaatggtg cattatcaag aggatgattt gcagaagcct atttcaagag
     4621 tagcaatttg tggtggaagc gggcagtctt tctataagga tgctttggca aagggggcag
     4681 atgtctatat cactggtgat atctactacc atactgctca ggatatgctg tctgatggct
     4741 tgttagcatt ggatccaggt cactatatcg aagtgctttt tgtggaaaaa atcgcaacac
     4801 tccttactca atggaaagag aaaaaaggct gggaactaga gattttacct agtcaagcat
     4861 cgaccaatcc tttccgtcat atctagttag aaagtgaaga caatgaaaaa agttgccatt
     4921 attggagcag gaattgtggg agcaacagct gcctactacc tctcgagaga aagtgaccta
     4981 gaggtgaccg tttttgacca tgagcaaggt caagccacca aggccgcagc aggaattatc
     5041 agtccttggt tttccaaacg ccgtaataaa gcctggtaca agatggcgcg cttgggggct
     5101 gatttttatg tggatttatt agctgattta gagaaatcag gacaagaaat cgacttttac
     5161 cagcgttcgg gagtctttct cttgaaaaag gatgaatcca atttggaaga actttatcaa
     5221 ctggccctcc agcgcagaga agaatctccc ttgatagggc aattagccat tctgaaccaa
     5281 gcctcagcta atgaattatt ccctggtttg cagggatttg accgcctgct ctatgcttct
     5341 ggtggagcga gagtagatgg tcacctctta gtaactcgtt tgctggaagc cagtcaggtc
     5401 aagttggtca aagaaaaagt gactctgaca ctcttatcat caggctacca gattggcgaa
     5461 gaggtgtttg atcaggttat tttggcaacg ggagcttggt tgggggacat gttagagcct
     5521 ttaggttatg aagtggatgt ccgtcctcaa aaaggacaac tacgagatta tcagcttgcc
     5581 caagacatgg aagattaccc tgttgtcatg ccagaagggg agtgggattt gattcccttt
     5641 gcaggtggga aattatcctt gggcgctacc catgaaaatg acatgggatt tgatttgacg
     5701 gtagatgaac ccttgctcca acaaatggag gaggcggcct tgcctcatta cccagtttta
     5761 gctagagtga cttcaagggc tgagcgtgtg ggaatccgtg cctataccag tgatttctct
     5821 cccttctttg ggcaggtgcc agaattggca ggtgtctatg cagccagtgg actaggttca
     5881 tcaggcctca caactggtcc tatcattggt taccatctag cccaactgat ccaagacaag
     5941 gagttgacct tggaccctga aaattaccca attgaaaact atgtcaaacg agtaaaaagc
     6001 gaataatact caatgaaaat caaagaacaa actaggaaac tagccgcggg ttactcaaag
     6061 cactgctttg aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt
     6121 gtggatagaa ctgacgaagt cagtaaccat acccatggca aggcgacgtt gacgtggttt
     6181 gaattggatt ttcgaagagt ataagcattt tactgaaatt ttatcaggta gtttaggatg
     6241 gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa aatgatctga gaatcgagga
     6301 aaaaagatgc aagaaaagat tttggtaact ggtggtgccg gttttattgg aacccacact
     6361 gttattgaat tgatccaagc aggccatcaa gttgttgtgg tggataatct tgtcaatagc
     6421 aatcgtaaga gtttagaagt tgttgaaaga atcacaggag ttgagattcc tttctatgag
     6481 gcagatattc gtgacacaga taccctcaga gatattttca agcaggaaga accgactggt
     6541 gtcattcact ttgctggttt gaaggctgtt ggcgaatcaa cacgtatccc tcttgcctac
     6601 tatgacaaca atatcgctgg aactgtcagc cttttgaaag ccatggaaga aaacaactgt
     6661 aaaaacatca tcttcagttc ttctgcgaca gtttacggag atccgcacac agtgcccatc
     6721 ttggaagatt tcccactttc agtgacaaac ccatacggtc gtaccaagct catgctagag
     6781 gaaattttga ccgatattta caaagcagac tcagaatgga atgttgtctt gcttcgttac
     6841 tttaacccaa tcggagccca tgagagtggt gatttgggag aaaatccaaa cggtattcca
     6901 aacaatctct tgccatatgt gactcaagta gccgttggaa aattagagca agtgcaagtg
     6961 tttggagacg attacgatac ggaagatgga acaggtgttc gtgactatat ccacgttgtc
     7021 gatttggcta agggtcacgt tgcagctttg aaaaaaatcc aaaaaggttc aggactaaac
     7081 gtttataacc ttggaactgg taaaggttac tcagttcttg aaattatcca aaacatggaa
     7141 aaagcggtgg gacgtcctat tccttaccgc atcgtagaac gtcgcccagg tgatatcgct
     7201 gcctgctact cagacccagc aaaagctaaa gcagaactcg gttgggaagc agaactcgac
     7261 atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca agcatccaaa tggatttgaa
     7321 gactaagatg atgatttcaa tcatcgtccc ttgtttaaac gaagaggaag tacttcctct
     7381 tttttatcag gctctggaag ctttacttcc agatttggaa acagaaatcg agtatgtctt
     7441 tgtcgatgat ggatcaagtg atgggacctt ggaactctta aaggcctatc gggagcaaaa
     7501 tccggcagtc cattatattt ctttctctcg aaattttggc aaagaagcag ccctttatgc
     7561 aggcttgcaa tatgcgacag gagatttggt ggtggtgatg gatgcagacc tccaagatcc
     7621 tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa aatgtagact tggactgcgt
     7681 tgggacacgg agaactagtc gggagggaga acccttcttt cgcagtttct gtgctgttct
     7741 cttttatcgc ctcatgcaaa aaatcagccc agtagctctg ccgtcgggtg tccgtgattt
     7801 tcgtatgatg agaaggtctg tagtcgatgc cattttaagc ttgaccgagt ccaatcgttt
     7861 ttcaaagggg ctcttcgcct gggtgggttt caaaacctac tatttggact atccaaatgt
     7921 cgaaaggcag gctggcaaga caagttggag ttttaggcaa ctctttttct actccattga
     7981 agggattatt aatttttcag attttccctt gattatagcc tttgtagctg gtctcctatc
     8041 ttgttttctt tctctgctga tgaccttttt tgttgtggtt cggaccctca ttttgggcaa
     8101 tccgacatct ggttggacct ctctgatggc tgttattctc tttcttggag gcattcaact
     8161 cttgaccatt gggattctcg gcaagtatat cagtaagatt tatttagaga ctaaaaaaag
     8221 accactttat cttatcaaag aaaaaagtga ccttcctgat tttacagaaa aaaataaagt
     8281 gaaaagacta taattttaca tggaaatgtg ctaaactaga gggagtggat tatcgccctt
     8341 gatttaggct tcctggtttc caatcagggc gcgagttggg caatttttaa cagcctctaa
     8401 gacatcctga ctaggagaaa tttctttttc cagttggtca gggtcatcgt aaaaacgcac
     8461 gattccatta tcgtggtaat caaataaatc agaataagtt tggcaaagcc cacaggcgat
     8521 acatcgttca ggtataagtg tgattttcat gttcatattt atattgtaat aagaaaagta
     8581 aaaaaaaaca aggagtaagg tatggcaaaa gaaccgtggc aagaagatat ctatgatcaa
     8641 gaagaatcaa gagcagagcg tcggcatcga aaccacggag gggctgatag gatggctaat
     8701 cgtattttga cgatcctagc tagtattttc tttgtaattg tggtggtgat ggtcatcgtt
     8761 ctcatctatc tatcatcggg gggaagtaat cgcacagcag ccttaaaaga ctttcatgat
     8821 tctgatgcaa gtgtagtaca aatctcatct tcaagcagtt ctcatcctga gcagagttca
     8881 gagccagaat ctacttctag tagttcagaa gaagctgcta atcctgaagg aacgattaaa
     8941 gttctcgcag gagaagggga agcagctatt gccgctcgtg caggaatctc cattgctcag
     9001 ttagaggcct tgaatcctgg gcacatggct acaggatctt ggtttgctaa tccaggtgat
     9061 gttataaaaa taaaatagga gccgatatga aaacaattca aattgctatt gatggtcctg
     9121 cttccagcgg taagagtacg gtcgcaaaga ttattgctaa ggattttgga ttcacctacc
     9181 ttgatacagg agctatgtat cgtgcagcga cctatatggc tcttaagaac caattaggag
     9241 ttgaagaagt cgaagccctt ctagccttgt tggaccagca tccaatcagc tttggacgtt
     9301 cagaaactgg agaccagctt gtttttgtag gagatgtgga tattacccat cctatccgtg
     9361 aaaatgaagt gaccaatcat gtttctgcta ttgcagcaat tcctgaagtg cgtgagaaac
     9421 tggtttctct ccaacaagaa attgcccagc aaggcgggat tgtcatggat ggtcgcgata
     9481 ttggaactgt tgtattgcca caagcagaat tgaaaatttt cctagtagct tctgttgatg
     9541 agagagcaga gcgtcgttac aaggaaaata ttgccaaggg aattgaaaca gaccttgaaa
     9601 ccctaaaaaa ggaaattgct gcgcgtgact acaaggatag tcatcgtgag acttctcctc
     9661 tcaaacaagc agaggatgct gtctaccttg atacaactgg tttgaacatt caagaagtag
     9721 ttgaaaaaat caaagcagaa gctgaaaaaa gaatgtaaat gtagaaaagc cgatagattg
     9781 atatcggttt ttttctaaat ttgtcaaaat gctgatttta gggtataata gttgctgttc
     9841 gagaaatttt gattttcaaa gaatagtgaa tgatgataag gagaaaccat gaacaattta
     9901 ccaaattgtc caaaatgtaa ctcagagtat gtctacgaag acggtgccct actggtttgc
     9961 ccagagtgtg ctcatgagtg gaatcctgct gaagttgcag aagtagaaga aggtcttgtc
    10021 gctatcgatg ccaacggaaa taaattgact gatggtgata cagtaactct catcaaggac
    10081 ttgaaagtaa aaggtgcgcc aaaagatttg aaacaaggga cgcgcgtgaa aaatatccgc
    10141 atcgtagaag gcgatcacaa tatcgactgt aagattgatg gttttggtgc catgaaactt
    10201 aaatcagagt ttgtgaggaa gatttaagca tgtcaaaaca ctataaactt gtattttata
    10261 gccgtatctt cttgtttcta gcggctttta cgggagttta tcttgaaatt actaagcatg
    10321 gtggttttgg gatgcttctc tattacacgg ttctgtccaa cctcttggta actattttta
    10381 ccctttatct tctaaaggtt atgagccgtg taggtgaaaa ttggcaaagg ccaagtctct
    10441 tgcgcttaaa aggtggggtc accatgagta tcatgattac ctgtgtgatt taccatttcc
    10501 tcttggcgcc cattgcgact aatttctata ccctagaaaa tttcctttgc cactatatcg
    10561 ttcccatctg gtttttagcg gataccctct tttttgacaa acagggtcaa tacaagattt
    10621 gggatccagc agtgtggacc attttaccct ttctgtatat gatgtttgct ctttttaatg
    10681 gcttggttct aaaactcaat attccaaatg ccaaggataa tcctttccct tacttctttt
    10741 tgaatgtgaa caagggttgg aatgttgtgt ttaagtggtg tctgattatc tttgttgcct
    10801 atatggtagc aggatttatt ttctacttta tcaagcaaat caagagaaag tcatcctaat
    10861 actcttcgaa aatctcttca aaccacgtta gtttccatct gcaacctcaa aacactgttt
    10921 tgaacaacct gcggctagct ttctagtttg ctctttgatt ttcattgagt atgagataca
    10981 agggattcat tttcgaattt aagaaggagt ctacaaacca atgaggcttc ttcttttctt
    11041 gcttatttga taactatcaa aaaagtagaa gattaagaga aatatagaaa gagatttcat
    11101 gaaacaattt ttagaacggg ccagcatttt ggctctctcc ctcgttttga ttacctcctt
    11161 ttccatttcg agtgccctac cagccatgtt tgactattat cagggttatt ctaaggaaca
    11221 aattgagctc ttggtgagct tgccttcctt tggaatcatg atgatgttac tgctaaatgg
    11281 tttcttagaa aaaatatttc ctgagcgctt acagattagt ttgggcttgc tgattttatc
    11341 attgagcggt acagctccct tctggtacca agcctatccc tttgtctttg gaacacggct
    11401 tctctttggt ttgggtcttg ggatgatcaa tgccaaggcc atttctatta tcagtgaacg
    11461 ctaccaagga aaaaggcgaa ttcagatgtt agggctacgc gcttctgcag aggtcgttgg
    11521 agcttctctc attaccttgg ccgtcggtca gttgttggcc tttggttgga cagctatctt
    11581 tctagcctat agtgctggat ttttggtgat gcccctttat ctgctctttg tcccttatgg
    11641 aaaatcaaag aaagaagtca agaaaagagc gaaggaagca agtcgtttaa ctcgagaaat
    11701 gaaaggcttg atttttacct tagctatcga agcggcagtt gtagtttgta ccaatacagc
    11761 tattaccatc cgtattccaa gtttgatggt ggaaagagga ttgggggatg cccagttatc
    11821 tagttttgtt cttagtatca tgcagttgat cgggattgtg gctggggtga gtttttcttt
    11881 cttgatttct atctttaaag agaaactgct cctctggtct ggtattacct ttggcttggg
    11941 gcaaatcgtg attgccttgt cttcatcctt gtgggtggta gtagcaggaa gtgttctggc
    12001 tggatttgcc tatagtgtag tcttgacgac ggtctttcaa cttgtctctg aacgaattcc
    12061 agctaaactc ctcaatcaag caacttcatt tgctgtatta ggctgtagtt tcggagcctt
    12121 tacgacccca tttgttctag gtgcaattgg cttactaact cacaatggga tgttggtctt
    12181 tagtatctta ggaggttggt tgattgtaat ctctatcttt gtcatgtacc tacttcagaa
    12241 gagagcttag gattgattcc taagtttttc ttttgatact caatgaaaat caaagagcat
    12301 agttgattga gtttggaata gtacgctgta gctgctaaaa tatttctaga aattaatttg
    12361 acttttctaa tagagttatt catatcttat ttcaatctac tatagaaagc tagccgcagg
    12421 ttgctcaaaa tagtgtgttg aggttgcaga tggaaactga cgtggtttga agagattttc
    12481 gaagagtatg agatttttat acccatacaa tatttgtttt aggtccttgt ttacagacta
    12541 atttcttgat aaaatagagg ttatgacgag atataaagca actatttcct atgatggtta
    12601 tgcctttgct ggctttcagc gccagtctca tgcgcgtagc gttcaggaag aaattgaaaa
    12661 aaccttgacc agattaaata aagggcaaac cattactgtt cacggtgctg gtaggacaga
    12721 tagtggggtt catgccctgg gacaggtcat tcattttgac ctgccttatc agatggatga
    12781 ggagaaactc cgttttgcct tggataccca gtctcctgaa gatattgatg tgatttcgat
    12841 tgagcttgtg gcagatgatt ttcattgccg ttatgccaaa catagcaaga cctatgagtt
    12901 tattgtggat agaggacgtc ccaaaaatcc tatgcgccgt cactatgcca cccactttcc
    12961 ctacccactc gatgtggaac gaatgcagat tgcaatcaaa aagctagagg gaacccatga
    13021 ttttaccggt tttacagcct ctgggactag tgtagaggat aaggttcgca ccatcacaga
    13081 agctagttta atagtcgatg agacaggaca atttttgacc tttacctttt caggaaatgg
    13141 tttcttgtat aaacagattc gcaatatggt ggggactctt ctcaaaatcg gtaacaaccg
    13201 catgccagta gagcagattg atctcatctt ggagaagaag gacaggcaac ttgcaggtcc
    13261 cactgcagca ccaaatggtt tgtatttaaa ggagattcgt tatgaagaat aatcgtattt
    13321 tagcactttc tggaaatgat atttttagtg gtggtggact gtcagctgat ttggctacct
    13381 ataccttgaa cggcttgcat gggtttgtag cagtgacttg tttgacagcc ttgacagaaa
    13441 aaggatttga agtctttcca actgatgata ccatttttca acatgaatta gatagcttac
    13501 gtgatgtgga atttggggga attaagattg gtcttctccc tactgtcagt gtggctgaga
    13561 aggccttgga ctttatcaaa caacgcccag gagtacctgt ggtgttggat cctgtcttgg
    13621 tctgcaagga aacgcatgat gtagctgtca gtgagctctg ccaagagttg attcgctttt
    13681 tcccttatgt cagtgtgatt acgcctaatc tcccagaagc agaattatta tccggtcagg
    13741 aaattaaaac cttggaagac atgaaaactg cagcgcagaa attgcatgat ttaggagcgc
    13801 cagcagtcat tatcaaggga ggcaatcgtc ttagtcagga caaggctgtg gatgtctttt
    13861 atgatggaca gacctttact atcctagaaa atccagttat ccaaggccaa aatgctggtg
    13921 caggttgtac ctttgcctct agcattgcca gtcacttgat taaaggtgat aaacttttgc
    13981 cagcagtaga aagctctaag gctttcgttt atcgtgctat tgcacaagca gatcagtatg
    14041 gagtaagaca atatgaagca aacaaaaaca actaaaatcg cccttgtatc cctattaacc
    14101 gccctttctg tggttctagg ttatttctta aaaatcccaa cacctacagg aattctaact
    14161 cttttagatg ctggtgtctt ctttgcggcc ttttactttg gtagtcgtga aggagcggta
    14221 gtcggaggac tagcaagttt cttgattgac ctcttatcag gctaccctca gtggatgttc
    14281 tttagcttgg tcaaccatgg cttgcaggga tttttcgcag gatttaaagg aaaaagtcag
    14341 tggttaggcc ttattttagc aactattgcc atggtaggag gctacgcctt gggttctact
    14401 ttgatgaatg gctgggcagc agccctccca gaaattctac caaatttcat gcaaaatatg
    14461 gtagggatga ttgtaggatt tattcttagt caaagtatca agaagattaa gtaatactct
    14521 tcgaaaattt cttcaaacca cgtcagcttc catctgcaac ctcaaaacac tgttttgagc
    14581 agcctgaggc tagctttcta gtttgcactt tgattttcat tgagtataaa gaggttgagt
    14641 aaaaagtatt tcaaataaga aaaacgcata gtatcaggtg ttgaatgaac taccccccaa
    14701 aaagttagac agaaaaa
//
LOCUS       DAVLTG010000046        13948 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLTG010000046 DAVLTG010000000
VERSION     DAVLTG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13948
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.047"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..230)
                     /locus_tag="VYN12_001597"
     CDS             complement(<1..230)
                     /locus_tag="VYN12_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415953.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     LISKYLVTNDQRRYCRYSDSDILVQFLFQLLTG"
     gene            complement(695..1888)
                     /locus_tag="VYN12_001598"
     CDS             complement(695..1888)
                     /locus_tag="VYN12_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1415954.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(2026..3468)
                     /gene="gtfA"
                     /locus_tag="VYN12_001599"
     CDS             complement(2026..3468)
                     /gene="gtfA"
                     /locus_tag="VYN12_001599"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1415955.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYCVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            complement(3745..3825)
                     /locus_tag="VYN12_001600"
                     /pseudo
     CDS             complement(3745..3825)
                     /locus_tag="VYN12_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3826..4659)
                     /locus_tag="VYN12_001601"
     CDS             complement(3826..4659)
                     /locus_tag="VYN12_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1415956.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(4673..5539)
                     /locus_tag="VYN12_001602"
     CDS             complement(4673..5539)
                     /locus_tag="VYN12_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1415957.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVNLFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(5553..6812)
                     /locus_tag="VYN12_001603"
     CDS             complement(5553..6812)
                     /locus_tag="VYN12_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1415958.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTSFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(6904..9066)
                     /locus_tag="VYN12_001604"
     CDS             complement(6904..9066)
                     /locus_tag="VYN12_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1415959.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            9174..10034
                     /locus_tag="VYN12_001605"
     CDS             9174..10034
                     /locus_tag="VYN12_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1415960.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKDKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            10031..10966
                     /locus_tag="VYN12_001606"
     CDS             10031..10966
                     /locus_tag="VYN12_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1415961.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            11112..12418
                     /locus_tag="VYN12_001607"
                     /pseudo
     CDS             11112..12418
                     /locus_tag="VYN12_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12522..12609)
                     /locus_tag="VYN12_001608"
     tRNA            complement(12522..12609)
                     /locus_tag="VYN12_001608"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12573..12575),aa:Ser,seq:gct)
     gene            complement(12616..12689)
                     /locus_tag="VYN12_001609"
     tRNA            complement(12616..12689)
                     /locus_tag="VYN12_001609"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12653..12655),aa:Ile,seq:gat)
     gene            complement(12725..12795)
                     /locus_tag="VYN12_001610"
     tRNA            complement(12725..12795)
                     /locus_tag="VYN12_001610"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12761..12763),aa:Gly,seq:tcc)
     gene            complement(12815..12887)
                     /locus_tag="VYN12_001611"
     tRNA            complement(12815..12887)
                     /locus_tag="VYN12_001611"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12852..12854),aa:Phe,seq:gaa)
     gene            complement(12891..12964)
                     /locus_tag="VYN12_001612"
     tRNA            complement(12891..12964)
                     /locus_tag="VYN12_001612"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12928..12930),aa:Met,seq:cat)
     gene            complement(12975..13064)
                     /locus_tag="VYN12_001613"
     tRNA            complement(12975..13064)
                     /locus_tag="VYN12_001613"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13026..13028),aa:Ser,seq:tga)
     gene            complement(13075..13148)
                     /locus_tag="VYN12_001614"
     tRNA            complement(13075..13148)
                     /locus_tag="VYN12_001614"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13112..13114),aa:Ile,seq:cat)
     gene            complement(13162..13235)
                     /locus_tag="VYN12_001615"
     tRNA            complement(13162..13235)
                     /locus_tag="VYN12_001615"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13199..13201),aa:Met,seq:cat)
     gene            complement(13241..13314)
                     /locus_tag="VYN12_001616"
     tRNA            complement(13241..13314)
                     /locus_tag="VYN12_001616"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13278..13280),aa:Pro,seq:tgg)
     gene            complement(13330..13403)
                     /locus_tag="VYN12_001617"
     tRNA            complement(13330..13403)
                     /locus_tag="VYN12_001617"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13367..13369),aa:Arg,seq:acg)
     gene            complement(13413..13498)
                     /locus_tag="VYN12_001618"
     tRNA            complement(13413..13498)
                     /locus_tag="VYN12_001618"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13462..13464),aa:Leu,seq:taa)
     gene            complement(13506..13577)
                     /locus_tag="VYN12_001619"
     tRNA            complement(13506..13577)
                     /locus_tag="VYN12_001619"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13543..13545),aa:Gly,seq:gcc)
     gene            complement(13600..13672)
                     /locus_tag="VYN12_001620"
     tRNA            complement(13600..13672)
                     /locus_tag="VYN12_001620"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13637..13639),aa:Thr,seq:tgt)
     gene            complement(13691..13772)
                     /locus_tag="VYN12_001621"
     tRNA            complement(13691..13772)
                     /locus_tag="VYN12_001621"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13736..13738),aa:Leu,seq:tag)
     gene            complement(13778..13850)
                     /locus_tag="VYN12_001622"
     tRNA            complement(13778..13850)
                     /locus_tag="VYN12_001622"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13815..13817),aa:Lys,seq:ttt)
     gene            complement(13875..13947)
                     /locus_tag="VYN12_001623"
     tRNA            complement(13875..13947)
                     /locus_tag="VYN12_001623"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13912..13914),aa:Asp,seq:gtc)
BASE COUNT         4428 a         3058 c         2487 g         3975 t
ORIGIN      
        1 cctgttaaca gttgaaagag gaactggaca aggatatctg aatccgaata acgacagtag
       61 cggcgttggt cattcgttac taaatactta gaaatcagct cttttagttt caactgggaa
      121 aaaagttcct gaaaaaagat aagaccacca tactgggtta aatgacctcc atcgaaagat
      181 agttggtaaa aagacttgtt ttggaagtga tgatttggta aactgttcat gtgagtttcc
      241 tttctttttg tgtttttttc tacacttata ccataaaggg gaaactcttt tttgtctagt
      301 aaaaaacacc cattgggtga aaaaagaaac catccaggat ctaagctaag gcaaggattc
      361 tggatggttt ttaaattagg ggtgaataat tggggtttta tactttaaaa tttctcgcta
      421 ccttatccac tatatgctcc tcgctatcac gtttctattc atagcctacg atttcactat
      481 tgctttctct gacaattctt atttcctgcg tcagacttaa aacgatctat ccccagacca
      541 ttttaatccg ctacctcacg atagtcaggc ttggggagcg ctattgtatt caccggtagt
      601 ggatccctac agaggactta cacctcagat gcacgacatg cccatcgtat aaaaaatctc
      661 ctacccaagg tagaagattt caaacttata aaacttaatc cgtcatgtcc gataccaaca
      721 ttcgatgctc caatggaata ctgcacataa ctagcaagaa aataaagcct gactgaatcc
      781 agaagagagc caagtcaaaa attccgtgca cagcaaccac tgtaaggaaa gatagataaa
      841 ggccgataat cggacgtttc cccgactcct gactcatatc catcatcaag cgaacaggag
      901 caacagaaga cagaactaat aaaatggtac ccacaattcc gtaactcaga atcgtatcaa
      961 tataaagact gtgggcatgt tcatgataag gagcatgtat ccgaggataa gagtgcatat
     1021 aggtcaatgg cccttcaccc caaaaaggat tttgcttaaa caaggccatc ccagcatccc
     1081 agatagaaat gcgttcttcc atagaagagt ctaaagtacc cattcgaact cccaaatcac
     1141 tagaaaagag gaaactcaaa ccaatcgcga agaccccaat actaagccaa aaggccttcc
     1201 agtttttaat agtcgtaaag agatagataa ttgctccagc gataatagca ggaaaggcag
     1261 ttcgattttg agtaaagttc aaaccaaaga gattaacaaa gcctgcaatc acacagaata
     1321 ctttcaacca attcaacttg gtcgttgtaa acagatagaa agcaatcata atacagaaac
     1381 aacaaataat tccataataa ttaggattaa agaaggtcac ttctgcccgg ttctgatgcc
     1441 acacctgcat attgggggaa agaaaagcat aattaaattt cttcacaatt tggaaatgtt
     1501 ctaaactggc aaaagcagct gacaagacac taccaaacaa gacgaactgc aaaatcaatc
     1561 gaaagaattt atgggataaa atcgactgat agtgcaaaaa gaaaatagta aatagaaaca
     1621 ttcctactga agccacaaga cccatccaat tttgtgcaag aatggatata acagtactat
     1681 agccaagaaa aagaagcagc atcgaatgct cccccatttt ctgaagaata cttttcatgt
     1741 ctcctgtaaa aatcagactg ataatatata aacagaatac aactacaaaa agataaaagg
     1801 gtaaaaagat actcaggata attcccaata aaatcagctc tttactagac aaccccttca
     1861 gcttttcaat aaagcctatt gatttcaaaa tgaatccttt ctctccaaat cagctgattc
     1921 agataatagt aagctatcct atattgtacc acttttttag caatttgaaa acaaaggaaa
     1981 cgttttccaa aataaaaacc ctattttatc caccatatca aggcttcaaa atgttacttc
     2041 aactccattc tcaattaccc gataagtctg attttgcaag tcaatttctg ctactgctgt
     2101 tacggactta tctttatttt gacgtttgat tacaatgctg tgagctgttg gtgtctctat
     2161 ctcagtagtc ccttctagat caaaggcttc tgaacggtta cggaaagaaa atagattgag
     2221 aagggccttc acaacaggtc gttgcacttc ttttgctatt tcctcgttgc tatagtaatg
     2281 acgattaata tttcgacctt ctttagtttc ttctaataat ttcaagtcat tcttgcctgc
     2341 taatagaccc acacagtaaa cctgaggaat acctggggca aaagcttgaa ttagacgagc
     2401 gagaaaatac ttgacatcat catctccaag cgctgaatag taggttgaat tgatttggta
     2461 gatatctaag ttgttatact cggcactaga gtacttacgt ttgacattgg ctccaacctt
     2521 atagagttca tttgaagcat agtcaatctc ctcatcggtc aggatatcct tgacatctac
     2581 tactccaatc ccatcatggg tatctagcgt cgtaaattgc ttcatcgggc tcatctttaa
     2641 ccacttagcc aaacgctctg ttctggaact gtaaagagta taaagtgtca ccattggaag
     2701 agcaaaatca taaacatagt aatcatggtc tgctatttta aactgaatcg aatagtgttc
     2761 atgaatctca ggtaaaagct ctgtcccata ctcagcagcg atatctcgaa ctttgtccaa
     2821 taaatcccaa atatctggtt ccacaaagaa atcattagta tccaatttct tcactgcata
     2881 agcaaaggca tctagacgaa tcaaatcaca cccattactt gccaagtgct gaatggtctt
     2941 acggataaat tccatagtta cttctttggt cacatcaaga tcaatctgct cctcaccaaa
     3001 ggtattccac aaatgttcca ctgaaccatc ttcaaacaca atctcttgct ttggtgcacg
     3061 atccttacgc ttgtaaatta aatctacatc agactgtgtc ggacggtttt ctggccaaaa
     3121 cttatcccag tttaaaaaga gagctttaaa ttcactggct tcatgttttt cttgatagtc
     3181 cttataatac ttggattgac gagaaatatg attaatcata aaatcaaaca taagataata
     3241 tttctcacct aaacgcttaa catcctccca atcaccaaaa gctgagtcca cttcgtcgta
     3301 gtcaactggc gcaaatccac gatcacctgt tgatgggaaa aatggtaaaa ggtgaactcc
     3361 tccaatagca tctccaaaat gctcttccaa attatcatat aagtctttaa gattatttcc
     3421 aaggctatca gaataggtaa tcaacatggt tttattttga atcggcatca ttactctcct
     3481 ttttctaatt gaagccaagt ctcatatgat ctggcttcgt aaatcaaatt cattttaaat
     3541 ctctatttat catcaaactc gtactaatat agactgtgat aaacaaagta ctactttctt
     3601 gttttctaca tagaattatc aacaagctga actcttcctc tgtgtcaaag actatagatt
     3661 ccatgagctc ttcttatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttacc
     3721 gtaggtatgg ttactgactt cgtcagtttc atccacaacc tcaaaacagt gttttgagca
     3781 acctgcggct agcttcctag tttgctcttt gattttcatt gagtattact tcactgcccc
     3841 gttgctcatt cctgaaatga tatggcgttg gaagaagaga tagacaatgg tgatactgat
     3901 aatgccgacc acgtaagagg caaagcttgg tccgtagtcg ttgaaatatt ggcctgcgta
     3961 gttgtattgg aacaaaggca gagtccacat tttggaatcc cggttcaaga caaggagtgg
     4021 caacatgaag tcattccaga accaaagggc attgatgatc atggttgtcg catgcatcgg
     4081 tttcatcatt gggaagatga tgcggaaata ggttgtaaat tgattagccc catcgatctc
     4141 tgctgcttca tccagacttt ctggaatcga gattttgata tagccaacat agagaaagag
     4201 ggtctgtgga atcgcatagg tcaagtagag caagatcaaa ccaaaggtat tagccaaacc
     4261 gagtttactc atcataaccg taatcggaat catgatgact tggaaaggta cgaagattcc
     4321 gaggattaag agggtataca tgatggtaaa gacttttctt ttactcatat tgcgagcgat
     4381 ggagtaggct gccataggga taaagatcat tactgcaagt aaagacaaga cagtgatgac
     4441 gacagagttc caataatagc ctccaatccc atcagctaag agacggctaa agttgtccca
     4501 tgtgaagttg gttggaaagc caaagaaatt atctacaata tccttagtgg gtttgaagga
     4561 actaaagagg gtagcaagga gcggcactaa aatcagaacc gatcctagaa tcaatagaat
     4621 gtatttgcca atcagggctt ttctttcatc ttgtttcatc atgcttctcc tcttaaattt
     4681 caaatttctt agatactctc aattggatga tcgaaatcac tacaattaag aggaacaagt
     4741 ttacggcaat ggcattggca taaccgaatt ggttgttttt aaaggcatag ttataaacca
     4801 agagcccaag tgaggttgtg gcattgtttg gaccaccacc ggtcatggca aagacttggt
     4861 caaaggcagt cagcccacct tttagggcta ggataaagac catagagaca cttggtagca
     4921 agtaaggcaa ttcaatgttc cagaaaactt gcttgctagt cgcaccatca atccttgctg
     4981 cctctgtaat ctcagttgga atagattgca aaccagctag gaagatgatg atgggcatag
     5041 ccaccccttg ccaaagaagg acaaagacag ccgcaaagat tgctccccac ttagtcccta
     5101 aaagactggt ttggagaaat tcaatatgaa gggcattccc aatcgctgga agaccgtagt
     5161 tgaagacttg cttgaagatc aaagccactg tcaaaccaga taaaacagct gggaagaaga
     5221 accaagcacg gaagaaggtt tggcctttga ttttagagtt caagacacgc gcaatgaaga
     5281 tcccgagtgc aatctcacca accaccatgg caatcgtaat gattgcggta aagccaatcg
     5341 cattcatgaa ttttggatcc atgaagagga gcttaaagtt gtttaagccg acaaatttgt
     5401 agttgtaagt caatcctgtc cagttggtaa aactgtaaaa ggctccttga aacatcggca
     5461 catagaagaa aattgcttgt aacaagaggg ggatgaccac aaaagcccat gcccaatatt
     5521 tttgtaatac ttttttcata gtctctctac tcctaatcca catccgcttt catcgggtta
     5581 aagaaggcat tcaaatcatt gaccatgcct tgtttatcac cggtcaagac atagttcatg
     5641 gtcaaggtat ggaagtctgc ttcactggtc cagtattgtt gcaaccagac caagtgacga
     5701 tccgtaaagg catattcggt cataccagca agcggtgaat cttctcctgc ttgtttgacc
     5761 ccttcgatcg ctgttggaga tccgtccaca tcgtagtatt tttgcatgac ttctggacgg
     5821 gtcatatatt ccacaaaggc attggcttct tttggatgtt tggtggtggc tgagatagac
     5881 catgccaagt ctcccgcacc aacggttaag ctttgtcctt tttcttttcc tggaatcatg
     5941 aaggttccaa tcttaaagtt cggtttttgt tcattaatcg ctgtgatcgc ccaagaccca
     6001 tttggtgtca tgaggacatc cccacgtgcg aaggctccga taacatcggt atagccagca
     6061 ccttcccagt tcttttgctt agagccattg atgcgaagga tgtccatgac cttgatatca
     6121 tctttcataa tcggatccga caatttaatg gcatttggtt gagaataacg aaggtattga
     6181 tttgcttctt ttcctccacc tgttgctgtc gcaaaggcta attgattgta accattgagt
     6241 gtccaagcat ctgcacctgc aattccaaat gatgtttgtc ctttagcaac gatatctttg
     6301 actaactgtt caaattcatc ccaggtttca ggaaccttca agcccagttc ttcgaattta
     6361 tctttgttgt agtaaattcc ataagcatta gctgtaaaag gaacgttata aactttttcg
     6421 tttacagcat atttttcagc gtaggcattt ttcacgcgtt tcaggtagtc tttgttgctc
     6481 aaatcttcaa aaacacctgc ttttgcccat tcttgcagtt cgatggactg tgggtaaata
     6541 ttgaccacat caggcacatc tcctgcgaga acgcgtgtct tcaatacttc accagcattt
     6601 ggtacattga cgactttgac cttgatctta gggttttcct tctcaaaatc acgagtgatt
     6661 tcttccaagg ttttggtcat ttcttttttc tggttgaaat actcgatggt cactgtgcca
     6721 tccgcagatt taccatagtt ggagcaagcg ccgagcccaa acaaagctaa acctgtagtt
     6781 gcaagaagtc cgattttttt ataccattcc attagaaagc ctcctttata aatttataca
     6841 cccttattga actgcacccc aaaagttaga cagaataaat ctaacttttg gggtcagtac
     6901 atatcatagt tttctaaaaa tatactgtct actcaaaaaa tctccttggg ataagataac
     6961 agttaagccc gcatacatta gttctgcacc tgagtaaact tcgccatttt cctgtaattt
     7021 atatagtccc tcttcatcca aatcttttaa ttttaaagtt gtttccatgg tctctacaac
     7081 agataaaacg cgaacgtagg ttacaatcgt ttgatttccg taattaaatt gtacagctgc
     7141 ttcattggat gcagtatcag gattaattag tctatactgc tgtcctaact gaactactgg
     7201 tcgtaattct ttatacaagt tcacctgatt agcaatcgta gctttctctt catctgataa
     7261 atttgtcaaa tcaagctcat agcccaaatt tcccatcatt gctacatggc cacgtgtttc
     7321 taatggtgtc attcgtccca tctgatgatt cggtactgct gacacatgag cccccataga
     7381 aatggttgga tagagatagg atgaaccgta ttgaattggt aaacgtgcaa tggcatcagt
     7441 attatcacta gcccagactt gtgggaaata gcgtatcata ccaagatcat ttcgtccacc
     7501 accaccagag caggactcaa agagaatatg gctgtgcttc tctgtcagat aagaaacgag
     7561 ttcgtaaagc cccagcatgt actgatgaga ttgcatctgt gtctctagat aagttaatcc
     7621 attccctagc ttagtgatat tgcggttcat atcccattta atgtaatcaa tctcatgata
     7681 agataggagt tgatctaaga cacttttcaa gtattctact acctgaggat tggcaagatt
     7741 aagtactaat tgattccgag aataagtatg ctcataatca ggaacctgaa tagcccagtc
     7801 aggatgttga cgatacaaat cactatctac agaaatcatt tcgggttcta accaaagtcc
     7861 aaactgcaaa cctctttcat ggatagctga aatcagactt tctagacttc cacccagttt
     7921 ttcctcatta acaacccaat cacctaaagc acgattatca tcaaaacgat tgccaaacca
     7981 accatcatct aatacaaaaa gttcaatgcc aactttctta gcttcatctg ctaactctaa
     8041 cagtttttct ctctgaaagt caaagtaagt agcttcccag ttattgatta gaattggacg
     8101 ttctttttta gaaaattcac ttagcataat gtgcttcagt acaaaattct gactttcatg
     8161 actaatacca gttaatccct gatctgaatg agtcactaaa gctaccggtg tttcaaagta
     8221 ttcctcaggg gctaacttcc aagaaaagtt ttctggatta atgccaatag ccacccgaac
     8281 ttcattcaat tgattttttt gaacaaaagc ttcaaagttg ccactataca ttagttgaat
     8341 agcaaacaca ttcccagcat cctctgtgac tccttgttcg catagtagaa gagctggtgt
     8401 ttgagcatga ccagaagcac ctcggtttga actaatcgaa aagattcctt gttctacctg
     8461 ttgacgtcta acagtctttt cacgagcata agcaccctgc agagttgcta tttcataatc
     8521 tgcagctgga aaatcagcca taaaagaaaa atctttatgg atgacaactt cctgattact
     8581 attattatct aatttactgt agctagtaat agtcgcatca ttattaaaag tagtataata
     8641 caaagtcaga ctaagttgag ccttagaatc ttctaacatt aagacaagag tctctgtatc
     8701 gtccatgcta tgtggagaag gtaagccctg tggaccattc tgacctttta aaatctttgc
     8761 ttctacaaat cgaaagtctg ttacttcagt tacactatgc tgaacctgta tagttggttt
     8821 cctaaaatct cctaagccat gttgtccaaa aatctgtcgc tgagtatcta aactaaaggt
     8881 tcgattagta gccgttggat ttcctgaaaa ggcatggtct cgttcataaa cactattgga
     8941 acctttatag ttcttaatag tctttcctaa atgtttcaaa agtaagtagc catttcgatt
     9001 ttcaataatc aaacttagat ttttactctc aacataaaat agattattct ctatcctaac
     9061 tcccatttac ttcacctcat cactttattg attatatttt atcacctgaa atcgctttcc
     9121 aaaatagaaa aatgtctcaa gaatatggta aaatgttagg taggaggtag cacatgttag
     9181 ttttttcaga ataccagact ggaacaatcg accttgccct aagcttttat ggatatgagg
     9241 aatgcacacc taattactct tttggtccag ccattcgtga tacatacgtc ctacattaca
     9301 ttactaaagg acaaggaaaa tttcattaca aggataaaat tgttgattta aaagaaggag
     9361 atttctttct attaaaacca gaggaactaa ccttttatca agcagatagt aaagaacctt
     9421 gggcctacta ctggttagga atcactggag ggaaatcccc tgattatttt gctctttctc
     9481 aaatttctga tcaatcctat ctcatccaat ctgaaacttg tcatacccag actactgcaa
     9541 aactcatctc agacattgtc cgcttcgctc agattacaaa atcaagtgaa ttagctcaac
     9601 tccatatcat gggacaactt catgaactga tgtttcatct gggaactatt gctcccaatc
     9661 agaaaaaaaa gaatatttca tcaacccacc aactctatct tgaatgcaaa cgattaattg
     9721 atagccacta tcctcaatca cttacaattc aagatttagc aaaagaacta tccgttcaca
     9781 gaagctactt atcaagcgta ttcaaagaat ttaatacctt atcacccaaa gaatacctac
     9841 tctacgttcg aatgcaccga gctagacaac ttctcgaaaa tacccaagag tccatcaagg
     9901 taattgcata ctcggtaggt ttttcagatc cactccattt ttcgaaagct tataaacaat
     9961 actttaatca gactccaagt catacaagaa aagaatactc tcaataccaa ctagtgagaa
    10021 aggcaacatt atgaaatcct accaagctgt ctaccaaatc ctatctaaag aaaccgacta
    10081 tatcagcgga gaaaaaatcg cagaaaaact atccctaagc cgaacatcaa tttggaaagc
    10141 tatcaagcga ctagaacaag aaggcattga aattgatagt atcaaaaata gaggatataa
    10201 actaatgaat ggtgacctta ttcttccaga gattctagaa gaaaatcttc caattaaagt
    10261 cagctttaaa cccgaaacaa aatcaacaca actagatgca aaagaagcaa ttgatttagg
    10321 ccatgaagca aataccctct atctagcttc ctatcaaaca gcaggccgag gacgttttca
    10381 acgttccttc tactcaccac aaggtggtat ttatatgaca ctccatctta aaccaaatct
    10441 cccctatgac aaattaccat cctacacact acttgtagct ggagctgtct acaaagctat
    10501 taagaaccta actttaatag atgtcgacat aaaatgggtc aatgatatct atctaaacaa
    10561 tcataaaatt ggaggaatcc ttactgaagc aatgacctct gtagaaactg gcttagtcac
    10621 agatatcatt attggagtag gtatcaattt cactattaaa gacttccctc aggaattaaa
    10681 agaaaaagct gccagcttat ttaaagctac agctcctata acaaggaatg aattgatcat
    10741 agaaatctgg cgtgctttct tcgaaacacc agcagaagag ctattatacc tatacaaaaa
    10801 acagtcattc attctaggaa aagaagtcac tttcacacta cagcaaaaag actacaaggg
    10861 acttgctaaa gacatctcag aaaatggaaa acttttagtt caatgtgata acggaaaaga
    10921 aatctggcta aatagtggcg aaatttctct caatagttgg aagtaaaata acacaattat
    10981 aatataaggc tctataatat ttgtagtggg taaatcccct atggatatta tggagcctat
    11041 ttttgtgtag aaaaaaagtc ccataagatt tataatgaaa agcgatcaaa caactcatta
    11101 gaaagattca tatggaacaa ttacatttta tcacaaaact actcgatatc aaagacacaa
    11161 atatccaaat tatagatgtc gtcaataggg attcacacaa agaaatcatc gccaaactgg
    11221 actacgacgc accatcttgc cctgagtgcg gaaaccaatt gaagaaatat gactttcaaa
    11281 aaccttctaa aattccttat cttgaaacga ctggtatgcc tactagaatt ctccttagaa
    11341 aacgccgttt caagtgctat cactgttcaa aaatgatggt cgctgaaact tctatcgtca
    11401 agaagaatca ccaaatccct cgtatcatca accaaaaaat tgcgcaaaag ttgattgaga
    11461 agatttctat gaccgatatt gctcatcagc tggccatttc aacttcaact gttattcgta
    11521 agctcaatga ttttcacttt aaacatgatt tttcttgtct tcctgagatt atgtcttggg
    11581 atgagtatgc ttttacaaag ggaaagatga gcttcattgc gcaagatttt aacaatctca
    11641 atatcatcac tgttcttgag ggtagaacac aagctatcat tcgaaatcac tttcttcact
    11701 acgatagagc tgtccgatgt cgcgtcaaaa tcattactat ggatatgttt agcccttact
    11761 atgacttggc taaacagctt cgctttcaaa tttctaggct caggctgaaa cagtctccca
    11821 gactgtttca ctcccgaatg ctaaaatcgt tcttgatcgc tttcacattg tacaacatct
    11881 tagccgtgct atgagtcgtg tgcgtgttca aatcatgaat cagtttcatc gaaaatccca
    11941 tgaatacaag gctatcaagc gctactggaa actcattcaa caggatagtc gtaaactcag
    12001 cgataaacat ttttatcgcc ctacttttcg tatgcattta accaataaag agattttaga
    12061 caagcttttg agctattcac aagacttgaa acaccactat cagctctatc aactcttgct
    12121 gtttcacttt cagaataagg aaccagagaa atttttcgga cttattgagg acaatcttaa
    12181 gcaggttcat cctatttttc agactgtctt taaaaccttc ctcaaagata aagaaaagat
    12241 tgtcaacgcc cttcaactac actattctaa tgccaaactg gaagcgacca ataatctcat
    12301 caaacttatc aagcgcaatg cctttggttt tcggaacttt gaaaacttca aaaaacggat
    12361 tttcatcgct ctgaacatca aaaaagaaag gacgaaattt gtcctttctc gagcttagct
    12421 tttcttcaac ccactacagt tgacaaagag ccttaagttt acggatctga agttttattg
    12481 tctctaaaaa caaaaaagag agttacaaac tctcattaaa acggagaata agggattcga
    12541 acccttgcgc cagttacccg acctaacgat ttagcaaacc gtcctcttca gcctcttgag
    12601 taattctcca attaatgggc acgagtggac tcgaaccacc gacctcacgc ttatcaggcg
    12661 tgcgctctaa ccacctgagc tacgcgccca agttaaaaaa cttggtaatt tgaacaaagt
    12721 tcaaagcggg tgacgagaat cgaactcgcg acaacagctt ggaaggctgt agttttacca
    12781 ctaaactaca cccgcataaa tactatcaat aaaatggcgc gagacggaat cgaaccgccg
    12841 acacatggag cttcaatcca ttgctctacc aactgagcta ccgagcctta ttgcgggagc
    12901 aggatttgaa cctacgacct tcgggttatg agcccgacga gctaccgagc tgctccatcc
    12961 cgcgttaata taaaaggagg atgtgggatt cgaacccacg cacgctttta cacgcctgac
    13021 ggttttcaag accgttccct tcagccggac ttgggtaatc ctccaatatt caaatggacc
    13081 ttgtaggact tgaacctacg accactcggt tatgagccga gagctctaac cagctgagct
    13141 aaaggtccga caagatcatt atagcggcga aggggatcga acccccgacc tcccgggtat
    13201 gaaccggacg ctctagccag ctgagctaca ccgccatgaa tcgggaagac aggattcgaa
    13261 cctgcgacac cttggtccca aaccaagtac tctaccaagc tgagctactt cccgagttaa
    13321 atagaaaaat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta gtcaggtact
    13381 ctatccagtt gagctaaggg tgctccatat tatgccgagg accggaatcg aaccggtacg
    13441 atcgttacca atcgcaggat tttaagtcct gtgcgtctgc cagttccgcc accccggcct
    13501 ctctaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt ggtgttctac
    13561 cactgaacta cgttcgcact gttttcttct atctaaaaat gccggctaca tgacttgaac
    13621 acgcgaccct ctgattacaa atcagatgct ctaccaactg agctaagccg gctcatttgt
    13681 tatatcttaa tgcgggttaa gggacttgaa cccccacgcc gttaagcgcc agatcctaaa
    13741 tctggtgcgt ctgccaattc cgccaaaccc gcatatatga cccgtactgg gctcgaacca
    13801 gtgacccatt gattaaaagt caattgctct accaactgag ctaacgagtc taaaataact
    13861 tgcgttacct taaacggtcc cgacgggaat cgaacccgcg atcttcgccg tgacagggcg
    13921 acgtgataac cgctacacta cgggacct
//
LOCUS       DAVLTG010000047        13018 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLTG010000047 DAVLTG010000000
VERSION     DAVLTG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.048"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..196
                     /locus_tag="VYN12_001624"
     CDS             <1..196
                     /locus_tag="VYN12_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1415962.1"
                     /translation="KFKPLTVEDKTYNHALSKERSKVENIFAKVETFKMFSTTYRNHR
                     KRFGLRMNLIAGIINHELGF"
     gene            387..2678
                     /gene="pcrA"
                     /locus_tag="VYN12_001625"
     CDS             387..2678
                     /gene="pcrA"
                     /locus_tag="VYN12_001625"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1415963.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2721..3401
                     /gene="radC"
                     /locus_tag="VYN12_001626"
     CDS             2721..3401
                     /gene="radC"
                     /locus_tag="VYN12_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1415964.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3398..4087)
                     /locus_tag="VYN12_001627"
     CDS             complement(3398..4087)
                     /locus_tag="VYN12_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1415965.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4105..4746)
                     /locus_tag="VYN12_001628"
     CDS             complement(4105..4746)
                     /locus_tag="VYN12_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1415966.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4829..5044)
                     /locus_tag="VYN12_001629"
     CDS             complement(4829..5044)
                     /locus_tag="VYN12_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1415967.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5052..5399)
                     /locus_tag="VYN12_001630"
     CDS             complement(5052..5399)
                     /locus_tag="VYN12_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1415968.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5404..6519)
                     /locus_tag="VYN12_001631"
     CDS             complement(5404..6519)
                     /locus_tag="VYN12_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1415969.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6529..7488)
                     /locus_tag="VYN12_001632"
     CDS             complement(6529..7488)
                     /locus_tag="VYN12_001632"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1415970.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7601..8170)
                     /locus_tag="VYN12_001633"
     CDS             complement(7601..8170)
                     /locus_tag="VYN12_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1415971.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8298..8969
                     /locus_tag="VYN12_001634"
     CDS             8298..8969
                     /locus_tag="VYN12_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1415972.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8953..9771
                     /locus_tag="VYN12_001635"
     CDS             8953..9771
                     /locus_tag="VYN12_001635"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1415973.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9768..10664
                     /locus_tag="VYN12_001636"
     CDS             9768..10664
                     /locus_tag="VYN12_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1415974.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10708..11682
                     /gene="pta"
                     /locus_tag="VYN12_001637"
     CDS             10708..11682
                     /gene="pta"
                     /locus_tag="VYN12_001637"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1415975.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11943..13018)
                     /locus_tag="VYN12_001638"
                     /pseudo
     CDS             complement(11943..13018)
                     /locus_tag="VYN12_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3810 a         2479 c         2801 g         3928 t
ORIGIN      
        1 caaattcaag ccgctaacag ttgaagataa aacctataac catgcgctat ctaaggagag
       61 aagcaaggtt gagaacatct ttgccaaagt agaaacgttt aaaatgtttt caacaaccta
      121 tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggta ttatcaatca
      181 tgaactagga ttctagtttt gcaggaagtc tattgaggta ttgagctagt ttatgaaaaa
      241 attgggtgaa aagtcgagtg ttttagaaac ccacagtgta gtattctagt ttcaatccac
      301 tatattttgc tactccccgt aaagtttcta ttttccctga tttctgatat aatagaaata
      361 ttgacttcaa gagtaaggaa gagaagatga acgcattatt aaatggaatg aatgaccgtc
      421 aggctgaggc ggtgcaaacg acagaaggtc ccttgctaat catggcaggg gctggttctg
      481 gaaagactcg tgttttaacc caccgtatcg cttatttgat tgatgaaaag ctggtcaatc
      541 cttggaatat cttggccatt acctttacca acaaggctgc gcgtgagatg aaagagcgtg
      601 cttatagcct caatccagct actcaggact gtctgattgc gaccttccac tccatgtgtg
      661 tgcgtatttt gcgtcgcgat gcggaccata ttggctacaa tcgtaatttt acaattgtgg
      721 atcctggtga acagcgaacg ctcatgaaac gtattctcaa acagttgaac ttggatccta
      781 aaaaatggaa tgaacgaact attttgggga ccatttccaa tgctaagaat gatttgattg
      841 atgatgttgc ttatgctgcc caagctggcg atatgtatac gcaaattgtg gcccagtgtt
      901 atacagccta tcaaaaagaa cttcgtcagt ctgaatccgt tgactttgat gatttgatta
      961 tgctgacctt gcgtctcttt gatcaaaatc ctgatgtttt aacctactac cagcaaaaat
     1021 tccaatacat ccacgttgat gagtaccaag ataccaacca cgctcagtac caattggtca
     1081 aactcttggc ttcccgtttt aaaaatatct gtgtggttgg ggatgcggac cagtctatct
     1141 acggttggcg tggtgctgat atgcagaata tcttggactt tgaaaaggat taccccaaag
     1201 ccaaggttgt tttgttggag gaaaattacc gctcaaccaa aaccattctc caagcggcca
     1261 acgaggttat taaaaacaat aaaaatcgcc gtcctaaaaa tctctggact caaaacgctg
     1321 atggggagca aatcgtttac tatcgtgccg atgatgagct ggatgaggct gtatttgtag
     1381 ccagaaccat cgatgaactt agtcgcagtc aaaacttcct tcataaggat tttgcagttc
     1441 tctatcggac taatgcccag tcccgtacaa ttgaggaagc cctgctcaag tctaacattc
     1501 cttataccat ggttggcgga accaaattct acagccgtaa ggaaattcgc gatattattg
     1561 cttatctcaa ccttattgct aatttgagtg acaatattag ttttgagcgt attatcaacg
     1621 agcctaaacg tggaattggt ccaggtacag ttgagaaaat ccgtgatttt gcaaatttgc
     1681 aaaatatgtc tatgctggat gcttctgcta atattatgtt gtctggtatc aagggtaagg
     1741 cagcccaatc tatctgggat tttgccaata tgatgcttga tttgcgggag cagctagacc
     1801 acttaagcat tacagagttg gttgagtccg tcctagaaaa aacaggttat gtcgatattc
     1861 ttaacgccca agcgactcta gaaagcaagg cacgggttga aaatatcgaa gagtttcttt
     1921 ctgttacgaa gaactttgat gacaccactg atgtgacaga agaggaaact ggtctggaca
     1981 aactgagtcg tttcttaaat gacttggctt tgattgccga cacagattca ggtagtcagg
     2041 agacatcaga agtgaccttg atgaccctgc atgctgccaa aggtctcgaa tttccagttg
     2101 tctttttgat tgggatggaa gaaaatgtct ttccacttag tcgtgcgact gaagatccag
     2161 atgaattaga agaagagcgc cgtctagcct atgtaggtat cacgcgtgca gagaaaattc
     2221 tctatctgac caatgccaac tcacgcttgc tttttggtcg taccaattat aaccgtccga
     2281 ctcgttttat taacgaaatc agttcagact tgcttgagta tcaaggtctg gctcgtcctg
     2341 caaatacaag ctttaaggca tcatatagca gtggtagtat ttcctttggt caaggtatga
     2401 gtttggctca ggctcttcaa gaccgtaaac gcggtgctgc cccaaaatca atccagtcaa
     2461 gcggtcttcc atttggtcaa tttacagctg gcgcaaaatc agcatctagc gaggcaaatt
     2521 ggtccattgg tgacattgct ctccacaaga aatggggaga gggaactgtt ctggaagttt
     2581 caggtagcgg tgctaggcag gaattgaaaa tcaatttccc agaagtaggt ttgaaaaaac
     2641 ttttagccag tgtggctcca attgagaaaa aaatctaatt ttccatcctt ctcacgaata
     2701 ataaagtgag gaggattttt atgtacagta tttcattcca agaagattca ctattaccaa
     2761 gagaaaggct ggccaaggaa ggagttgaag cgcttagtaa ccaagagttg ctagctattt
     2821 tactcaggac aggaacacgt caagctagcg tttttgaaat tgcccaaaaa gtcttgaaca
     2881 atctttcaag cctaacggat ttgaaaaaaa tgaccctgca ggaattgcag agtttgtctg
     2941 gtattgggcg tgttaaggcc atagaattac aagctatgat tgaactgggg catcgtattc
     3001 acaaacacga gactcttgaa atggaaagta ttctcagcag tcaaaagttg gccaagaaga
     3061 tgcagcagga attaggggat aaaaaacaag agcacctggt ggcactctat ctcaatactc
     3121 aaaatcaaat catccatcag cagaccattt ttatcggttc tgtaactcgt agtatcgctg
     3181 aaccgcgaga gattcttcac tatgcaatca agcatatggc gacttctctt atcttggtcc
     3241 acaatcatcc ttcaggagcg gtagcgccta gccaaaatga tgatcatgtc actaaacttg
     3301 ttaaagaagc ctgcgaactg atggggattg ttctcttgga ccatttgatt gtctctcatt
     3361 ctaattactt tagttatcgt gaaaagacag atttaatcta aagttcatta acgacatagt
     3421 caaagagttt cttatctttg ggacgatttt caaaaagaag ttctggatgc cattggacac
     3481 cgagaaaggc gacatcatcc gtactcatga cagcctcaat gataccatct ttaggatcat
     3541 gagccacaac ttttaaattt ggtgctaagt ccttgatgct ctggtggtgg aaggagttga
     3601 tatgagagat ttctccatag atttcttgga gaacggtatc tggttctgtt accaagcgtt
     3661 gagttgtgta ctcaacagaa gaatcctgcc aatggtcttc gatatcttgg tacaaagttc
     3721 cacccatggc aacgttaaag agttgggtac cacggcagac agagaaaatg ggctttttct
     3781 gtttaatagc ttccttgatg agggccagtt cgaagatatc tctttgaagg tgataatcat
     3841 cgctatcaat ggttttgggt tcgccataga attttggatc gacattttgc ccacctgtca
     3901 agatgagctt gtcaatcaaa ctgatatagt ggcaggccat ttcttgatca ccaatcggta
     3961 ggatgatagg aatccctcca gcatctttaa cgccttcaac aaagcctttt gctgcgtagc
     4021 tcatcatgat gtcatcatct ggatgagttt tttcgtttcc tgtaatccca ataactggtt
     4081 ttttcataaa atgattttcg ctttctaatc ctcttttcgc atgaagtaga ggagggtttg
     4141 gagttcactt gtcaaatcga catactgaac gaccacgtct tttggtaaat gcagatggac
     4201 tggtgaaaaa ctgagaattc ctttcacacc agcatcaacc aagagattag caacctcttg
     4261 tgacttgacg ctgggaacag ttaggatagc agtcttcaca tcagcatcct tgattttatc
     4321 cttgatctga gaaatcccgt aaatgggaat cccgtcagga gtttgggtac cgacttcagg
     4381 atggtcgtct aggtcaaagg ccatgataat cttcatcttg ttacgttcgt ggaagcggta
     4441 gtggagaagg gcatggccca tatttccaat accaaccagc atgacattgg taatagagtt
     4501 gtcattgagc aaatcggcaa aaaatgtcat tagttttttg acatcatagc caaaaccacg
     4561 acgaccaagt tcaccaaaat aggaaaaatc acgacgtacg gtcgctgaat caataccgat
     4621 agcctctgca atttgcttag agttggcacg ttcaatcttt tctgcatgaa atctcttaaa
     4681 aattcgatag tagagagaga gtctttttgc tgtagctttt ggaatagcaa actgtttatc
     4741 tttcacaaaa tcacaacctt tctattcttc tattttatag aaacattgtg aaaaaatcaa
     4801 caaaaataag aaaaaactaa gaaaaatctt agttttgatg taaaaaatct gcatgagata
     4861 gaaaacggta gaggtctccg accagaccct gataaacttt ttggccccta aaagtcagag
     4921 aagtcacata aagtgtatct ggtaaggtta cacatcctga caaagtcaac atgagagcct
     4981 catgatcctc atacttgaga gtacgctcta catgatagca gtccttatag gtcagttcaa
     5041 acattttggc tctatctttc cgattttgta aagacaccac gttctaccaa gctatccatg
     5101 aggaagtaga atttttcctg atgaatatgg tggtcttctg atttgaaaat atcaactaga
     5161 cgaaggccaa acttgtcagt gatattgatt ttagcccctg taagttcctt gttaatgatg
     5221 attttgagtt ggaagccttc accgctgttt ggcacttttt ccaaaaggcg agtcagttca
     5281 tagttaccaa ccttagtttc aaaaaaggtg ttatctttga gggtgaattt tttaacagaa
     5341 gggctaagag tgtaatcgta acgacaattt tttaactgaa tgattttttc aaatgccata
     5401 tggctaacct ccgataattt cttttaaggt ttttgcgagg gtttgtaggt cttcaacggt
     5461 attttgtggc gacaaactga tgcgaaggga ttccttcaag cgttctgaat ttgcgccata
     5521 catggcttca agaacatggc tggattggac aacgcctgca gtacaggctg agccagtaga
     5581 gattgaaatt ccagctaaat ctagccgaag gagtaagagg tcatttttct gaccaggaaa
     5641 tccaatattg agaacataag ggagatgatg ttttcctcta ttcaggtaat actgaatgcc
     5701 ctccagctct gccagaaagg cagtttctag attttgtaca tgttgaaaat gttcttcttg
     5761 tttttctagg tcttctttta gggctgcaac catgcctacg atggcaggca gattttcagt
     5821 tcctgcacgt tttttctgtt cctggtctcc gccatgtaga taggaatcaa agtccatgct
     5881 agatgcgtag agaaaaccga ttcccttagg accatggaat ttgtgggcag aagcagtgag
     5941 aaaatcaatg cccaattctt ctgaatgaat tgggatttta ccaatagcct gaactgcatc
     6001 aacatgatag gcagcagggt gttgcttgag tatttggcca atttcagcga tgggcagtag
     6061 gtttcctgtc tcattattgg caaacatggt agaaaccaaa atcgtatcgt cacgtaaagc
     6121 cttttgaatt tgctgggctg tgatttcttg attttctggc tggataatgg ttgcttcaaa
     6181 cccaaagtgt tgaaccaagt aatcaattgt ttcaaggaca gcatggtgct cgatggcagt
     6241 tgtgatgata tgttttcctt gttcttggtg acgaagacag tagccaatga tggtagtatt
     6301 attgccttca gtcccaccag aagtgaaaaa gatatgttga ggttttgtcc ttagtaactg
     6361 ggctagttcc tgacgggctt ctcgcaagag tttgccagct tgacgaccat gaccatgaat
     6421 actagaagga tttccgtggg tttcttgcat aaccttggtc atagctgaaa tagcaactgc
     6481 tgacatagga gtcgttgcag cattgtccaa ataaatcaaa gaatcacctt atttcttttt
     6541 attgtaggca aagagtgggc tgactggttt tctctcgtga atacggacga tagcatcacc
     6601 aattaactca ctagcagtga tgtagcatac atttttagga gttttttctt ttgttgctac
     6661 tgaatcagtc acaagaattt ctttaatatt agtattgtca agaagctcag cagctccctc
     6721 gacgaagaga ccgtggctag aaacagcata aatttctgta gctccttcac gttcaacgat
     6781 tttagaagct tcagagaagg tacgtcctgt atttaaaata tcatcaatca agatagcttt
     6841 cttaccttca acatcaccaa taatataacc ttcgttacga gttgcatcgt cttgagggta
     6901 gtcgataatg gcgataggag catcaagata ttcagccagg ctacgcgcac gtttgacacc
     6961 tgaattttta gggctaacga caacaacatc tgaaccaagc aatcctttat cgcagtaatg
     7021 ttttgcgaat aggggaacag tgaaaagatt atccactgga atatcaaaga aaccttgaac
     7081 ctgaacggca tgcaaatcaa gagtcaggat acgatcaact ccagccttaa ccagcatatt
     7141 ggcaactagt tttgctgtaa gtggctcacg aggacaagca atgcggtctt gacgtgcata
     7201 gccaaaatat ggaaggacaa cgttgatact gtgggcactt gcacgcacac aagcatcgac
     7261 catgattaac aattccatta ggtggttgtt gacagggaaa cttgttgatt ggatgatgta
     7321 aacatcataa ccacggacac tttcttcgat atttacttgg atttctccgt ctgaaaattg
     7381 acgtgatgat agttttccaa gtgggacacc aacagcttgg gcaatttttt gtgcaatctc
     7441 ttggttagag ttgagtgcga aaagtttcat gttttttcta tctgacatta tagaccgtcc
     7501 tctgtaaact ttataaatcc tagttatatt taccttacat atatgaactg ggatttgtgt
     7561 atttttatct tttctatttt accaaaaaat ggagattatt tcagctattt ttcatacttt
     7621 tgacaaatcg aaccaatttt gaaggagctt tttggtagga aatctgattt ttctctaaaa
     7681 attgtcggaa atcctgtttg ccttgctcat gattttccac ttcaagctcc aattcgtaat
     7741 ctgttatatc aaagtatcgg ctctgatcca gtgccatgag accaatagct gttttcattt
     7801 catagcgaag cgttgttaga caaccaagaa cctgccagtt cttactttgg ataccatgtt
     7861 tcgccaattc atccagtact agcccttgag gaagttcttc cttactcaga tagttctcag
     7921 catcttttag ttgcaatttt tggttgtatt ccatgtttcc aacactctgc gggactttga
     7981 gtgtcaactc agcccagtct tcaaaggttc gaatgcgcat agcgactttc ttttctcgca
     8041 gttcaaaatc aggcgtgtcg atgtagtaat ttgtttgaag aacaggagtg acacctgtga
     8101 actggtcttt tagacgattg tattcatctt ttttcaatag tgttttcaat tcaatttcta
     8161 aatgtttcat ttttcttacc tttttttatc gttgaaagcg gatttatggt ataataagca
     8221 ttgtatttat tgtatatgaa tctggagaaa aaatcaaaga tatttttgac ggataatatg
     8281 agaacaaggg agaatatatg accttagaat gggaagaatt tctagatcct tacattcaag
     8341 ctgttggtga gttaaagatt aaacttcgtg gtattcgtaa gcaatatcgt aagcaaaata
     8401 agcattctcc aattgagttt gtgaccggtc gagttaagcc aattgagagc atcaaagaaa
     8461 aaatggctcg tcgtggcatt acttatgcga ccttggaaca cgatttgcag gatattgctg
     8521 gcttacgtgt gatggttcag tttgtagatg acgtcaagga agtagtggat attttgcaca
     8581 agcgtcagga tatgcgaatc atacaggagc gagattacat tactcataga aaagcatcag
     8641 gctatcgttc ctatcatgtg gtagtagaat atacggttga taccatcaat ggagttaaga
     8701 ctattttggc agaaattcaa attcgtactt tggccatgaa tttctgggca acgatagaac
     8761 attctctcaa ctacaagtac caaggggatt tcccagatga gattaagaag cgactggaaa
     8821 ttacagctag aatcgcccat cagttggatg aagaaatggg tgaaattcgt gatgatatcc
     8881 aagaagctca ggcacttttt gatcctttga gtagaaaatt aaatgacggt gtaggaaaca
     8941 gtgacgatac agatgaagaa tacaggtaaa cgaattgatc tgatagccaa tagaaaaccg
     9001 cagagtcaaa gggttttgta tgaattgcga gatcgtttga agagaaatca gtttatactc
     9061 aatgatacca atccggatat tgtcatttcc attggcgggg atggtatgct cttgtcggcc
     9121 tttcataagt acgaaaatca gcttgagaag gtccgcttta tcggtcttca cactggacat
     9181 ttgggcttct atacagatta tcgtgatttt gagttggaca agctagtgac taatttgcag
     9241 ctagatactg gggcaagggt ttcttaccct gttctgaatg tgaaggtctt tcttgaaaat
     9301 ggtgaagtta agattttcag agcactcaac gaagccagca tccgcaggtc tgatcgaacc
     9361 atggtggcag atattgtaat aaatggtgtt ccctttgaac gttttcgtgg agacgggcta
     9421 acagtttcga caccgactgg tagtactgcc tataacaagt ctcttggcgg tgctgtttta
     9481 caccctacca ttgaagcttt gcaattaacg gaaattgcca gccttaataa tcgtgtctat
     9541 cgaacactgg gctcttccat tattgtgcct aagaaggata agattgaact tattccaaca
     9601 agaaacgatt atcatactat ttcggttgac aatagcgttt attctttccg taatattgag
     9661 cgtattgagt atcaaatcgc ccatcataag attcactttg tcgcgactcc tagccatacc
     9721 agtttctgga accgtgttaa ggatgccttt atcggtgagg tggatgaatg aggtttgaat
     9781 ttatcgcaga tgaacatgtc aaggttaaga ccttcttaaa aaagcacgag gtttctaagg
     9841 gattgctggc caagattaag tttcgaggtg gagctattct ggtcaataat caaccgcaaa
     9901 atgcaacgta tctattggac gttggagact acgttaccat tgacattccc gctgagaaag
     9961 gctttgaaac cttggaggct attgagcttc cattagatat tctctatgag gatgaccact
    10021 ttctagtctt gaataaaccc tatggagtgg cttctattcc tagtgttaat cactctaata
    10081 ccattgccaa ttttatcaag ggttactatg tcaagcaaaa ttatgaaaat cagcaggttc
    10141 acattgttac cagactagat agggacactt ctggcttgat gctctttgcc aagcacggtt
    10201 atgcccatgc acgattagac aagcagttgc agaagaaatc tatcgagaaa cgctactttg
    10261 ctttggttaa gggagatgga catttggaac cagaagggga aattattgct ccgattgcgc
    10321 gtgatgaaga ttccattatt accagacgag tggctaaagg cggaaagtat gcccatactt
    10381 catacaagat tgtagcttct tatggaaata ttcacttggt ctatattcac ctgcacactg
    10441 gtcgaaccca tcaaatccga gtccattttt ctcatatcgg ttttcctttg ctgggagatg
    10501 atttgtatgg tggtagtctg gaagatggta ttcaacgtca ggctctgcat tgccattacc
    10561 tatcctttta tcatccattt ttagagcaag acttgcagtt agaaagtccc ttgccggatg
    10621 atttcagtaa ccttattacc cagttatcaa ctaatactct ataaaaactg tctcagagta
    10681 taattattat cttaaaggag aaaactcatg gaagtttttg aaagtctcaa agccaacctt
    10741 gttggtaaaa atgctcgtat cgttctccct gaaggggaag agcctcgtat tcttcaagca
    10801 acaaaacgct tagtaaaaga aacagaagtg attcctgttt tgcttggaaa tcctgaaaaa
    10861 attaaaattt atcttgaaat tgaaggaatc atggatggtt atgaggtcat cgaccctcaa
    10921 cattatcctc aatttgaaga aatggtttct gccttggtgg agcgtcgcaa gggcaaaatg
    10981 actgaagaag atgtacgcaa ggttttggtt gaagatgtca actactttgg tgtgatgttg
    11041 gtttacttgg gcttggttga tggaatggtg tcaggagcga ttcactcaac agcttcaaca
    11101 gttcgcccag ctctacaaat catcaaaact cgtccaaatg taactcgtac ttcaggagcc
    11161 ttcctcatgg ttcgtggtac ggaacgttac ctatttggag actgtgccat taatatcaat
    11221 ccagatgcag aagccttggc tgaaattgcc atcaactcag caatcacagc taagatgttt
    11281 ggcatcgaac ctaaaattgc catgttgagc tattctacta aaggttcagg gtttggtgaa
    11341 agcgttgata aggtcgttga agcaactaaa attgctcacg acttgcgtcc tgaccttgaa
    11401 atcgatggtg agttgcaatt tgatgcggcc tttgttcccg aaactgcagc tctgaaagct
    11461 ccgggaagta cagtagctgg tcaagcaaat gtcttcatct tcccaggtat cgaggcagga
    11521 aatatcggtt acaagatggc tgaacgcctg ggtggctttg cggctgtagg acctgttttg
    11581 caaggtttaa acaagccagt taatgatctt tctcgtggat gtaatgcaga tgatgtttac
    11641 aagttgaccc tcatcacagc agctcaagca gttcatcaat agtgaaaact ataaagtgat
    11701 atactatgct atactgtagt tatgaaacta tgtacgaaaa gcactgccat taattcctga
    11761 gaactaaatt actgattggt gtcaaaaagg aaaacttcca agcgatgata tcctgtctat
    11821 acacgaccta tagaaatctg taatatacat atccgtaaaa cgataaattc cctttttgat
    11881 tttaaatgag tatgaaaaga gaattttttg gctctttgtc aactgtagtg ggttgaagtc
    11941 agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgataaaa
    12001 atccgttttt tgaagttttc aaagttccga aaaccaaagg cattgcgctt gataagtttg
    12061 atgagattat tggtcgcttc caatttggcg tttgaatagg gtagttgaag ggcgttgacg
    12121 attttctctt tgtcctttag aaaggtttta aagacagtct gaaaaatagg atgaacctgc
    12181 ttaagattgt cctcaataag tccgaaaaat ttctctggtt ccttattctg aaagtgaaac
    12241 agcaagagtt gatagagctg atagtgatgt ttcaagtctt gtgaatagct caaaagcttg
    12301 tctaaaatct ctttattggt taaatgcata cgaaaagtag ggcgataaaa atgtttatcg
    12361 ctgagtttac ggctatcctg ttgaatgagt ttccagtagc gcttgatagc cttgtattca
    12421 tgggattttc gatgaaactg attcatgatt tggacacgca cacgactcat agcacggcta
    12481 agatgttgta caatatgaaa gcgatcaaga acgattttag cattcgggag tgaaacagtc
    12541 tgggagactg tttcagcctg agcctagaaa tttgaaagcg aagctgttta gccaagtcat
    12601 agtaaggact aaacatatcc atagtaataa ttttgacgcg acatcggaca actctatcgt
    12661 agcgaagaaa gtgatttcga atgatagctt gtgttctacc ctcaagaaca gtgataatat
    12721 cgagcttttc aaaatcttgc gcaatgaagc tcatctccat ctcccgattg aaacagtcac
    12781 tccccggact gtttcaacct cccaagacat aatctcaggc agatttctaa aattacactc
    12841 aaagtggaag tcattgagct tgcgaatgac agttgaagtt gaaatggcca gctgatgggc
    12901 aatatcagtc atagaaattt tttcaattaa cttttgagca attttttggt tgatgatacg
    12961 agggatttgg tgatttttct ttaccagggg agtctcagca accatcattt ttgaacag
//
LOCUS       DAVLTG010000048        12704 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLTG010000048 DAVLTG010000000
VERSION     DAVLTG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.049"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..374)
                     /locus_tag="VYN12_001639"
     CDS             complement(<1..374)
                     /locus_tag="VYN12_001639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415976.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLK"
     gene            complement(371..1507)
                     /locus_tag="VYN12_001640"
     CDS             complement(371..1507)
                     /locus_tag="VYN12_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415977.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            complement(1514..1810)
                     /locus_tag="VYN12_001641"
     CDS             complement(1514..1810)
                     /locus_tag="VYN12_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV1415978.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(2340..3233)
                     /locus_tag="VYN12_001642"
     CDS             complement(2340..3233)
                     /locus_tag="VYN12_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1415979.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(3987..4217)
                     /gene="blpU"
                     /locus_tag="VYN12_001643"
     CDS             complement(3987..4217)
                     /gene="blpU"
                     /locus_tag="VYN12_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1415980.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(4420..4710)
                     /locus_tag="VYN12_001644"
                     /pseudo
     CDS             complement(4420..4710)
                     /locus_tag="VYN12_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(4756..4989)
                     /locus_tag="VYN12_001645"
     CDS             complement(4756..4989)
                     /locus_tag="VYN12_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1415981.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(4995..5987)
                     /gene="plsX"
                     /locus_tag="VYN12_001646"
     CDS             complement(4995..5987)
                     /gene="plsX"
                     /locus_tag="VYN12_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1415982.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFVVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(5984..6754)
                     /gene="recO"
                     /locus_tag="VYN12_001647"
     CDS             complement(5984..6754)
                     /gene="recO"
                     /locus_tag="VYN12_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1415983.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(6751..7920)
                     /locus_tag="VYN12_001648"
     CDS             complement(6751..7920)
                     /locus_tag="VYN12_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1415984.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            8069..9079
                     /locus_tag="VYN12_001649"
     CDS             8069..9079
                     /locus_tag="VYN12_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1415985.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(9282..9362)
                     /locus_tag="VYN12_001650"
                     /pseudo
     CDS             complement(9282..9362)
                     /locus_tag="VYN12_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9397..9834)
                     /locus_tag="VYN12_001651"
     CDS             complement(9397..9834)
                     /locus_tag="VYN12_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1415986.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(9919..12552)
                     /gene="polA"
                     /locus_tag="VYN12_001652"
     CDS             complement(9919..12552)
                     /gene="polA"
                     /locus_tag="VYN12_001652"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1415987.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
BASE COUNT         3914 a         2916 c         2021 g         3853 t
ORIGIN      
        1 tccttcaata atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt
       61 atttcaataa gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga
      121 ccagatatac ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa
      181 atcggaaaac agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat
      241 gtaaattgta attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag
      301 cttaaaagta aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa
      361 ccactttttc tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata
      421 aaaccagaaa actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct
      481 tataatagac ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac
      541 tttttatatc attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta
      601 agaaagagat taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt
      661 tagaatgatt aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat
      721 gattccctat tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg
      781 gtatttttgt gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa
      841 gaatactaat caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca
      901 atataaatag actgctacga aatctttttt gactcattcg actgctttta aaatagaaat
      961 tactcgcatg attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat
     1021 aaattacaac ttgtccttgt tctatagaca atagtcctat agataaaaat aagaacaatt
     1081 tacttataat tgaaaacaaa ctaggtagaa ttaaagaaat aatttgaata gctatcaaac
     1141 aaagagtaat ggataaataa aaatatccaa taatatctag aaaatacaaa ataaataaat
     1201 aaatgaatga ttgtaaaatt tggaaagaat aatatttctt gacaatggca agaagataga
     1261 gaaaaatata gtttttcctt atatagaaag tatttatttt tttactttgg ataggcagtt
     1321 tcatattata acgattcaaa gtagcgtaat ctactaccaa aaaaagtaaa aataatttcc
     1381 cttgaaaagg aagatagctt ttaaaataga ttgacaaact tatgataaca aaaaacaaaa
     1441 gggttatccc aataaaatta agataaccta aaatactttc acattctttt ttagaaagta
     1501 ttttcatcta gttctaccat agagctgctt tagcagcacc tttctttttc aatatataaa
     1561 gaactgttgc tgcaataccc gaaccaatag aacctactcc tgtgattgca cctacaattg
     1621 aaattactgc tgtaactgta ctataagcac taatcaaatt gactacagta gcagcagctt
     1681 ttgtcgaaat tcctaatgtc ccagccaaca taggaaaaga aacaacacct aagcttaacc
     1741 aactaatgac tgctaacatt gctgaaacaa taagaaattt attatgaaat tccattcttt
     1801 tagatttcat tttagtgtac tccttttgta tattatgtat gttttattga gagttaattc
     1861 gcacatgttg tattcctaac tctcttcaaa tgttcgtcta tattttatac tacttttatt
     1921 aacatatcta taataaataa attactacta cattttccta gattatcaaa ttacttttat
     1981 atcactaaga ctcaataaaa gataatgtct atttaacttt tatacgatta ctacctcttt
     2041 ttagtttaca cttcctacat cataaataaa catactcaac cctcacaatc tccaaataac
     2101 tcttctatat cattgaaaat tgagtttcat cctctatact aatgtaggac attcctttaa
     2161 tccaatataa gaataccttg ttccattaat ctctacccga tattatagat agaaccaaat
     2221 tcctatactt aaaaggacaa ataacgttcc aaccataata aacctccttt ctttttgaga
     2281 acgttttctt tataggttta gtatagcaaa aacatgaaaa aaacaacatg acttagaagt
     2341 caggttgttg ggaaatctat ctgtttttct gctaaaattc tctgaactaa tacctgatcg
     2401 tctagcaatt ctgctagaga aatcgccttt tcatagaaac tttctgcctc taaaatattc
     2461 ttgtctacaa ataaagcata ttttgccttt agcaaaaata gatgaggtcg gtaaaaaaca
     2521 tgtcttgttt tagcaataat tttctcaaat gtttgaatat atatcagact atcttctgtc
     2581 tgaatttgga taaataggct cagaagaact ttttccattt gaactaggct agccttatct
     2641 tcatattctg aacatagcaa tactttttga gctaactcct caaaatgttc tttatcttct
     2701 aatcccatag cacaacaaaa gaaatacaat tcaataatca acaaatcatt tacagaaaaa
     2761 tatttctttt ttaataactg ctggaaatat tcttccacta accctaaacc gtaggtcaca
     2821 tctgaactac cataaatatc aaaacgagct tgtgtcacat ccacaattaa ctgctcttcc
     2881 tcaggcaaat tctcataata gttttcatat atttcctcaa gtatagcttc ttttcgttcg
     2941 attcttccct tatcagcgta ggtttgagaa tgaatcagct catctttgag ttttaggaat
     3001 ccttttggaa tctctataac cttaacatcc acaatattct gtaatgatac tccaagttta
     3061 tccgcaatca ataataattt aggaagtgtt gctaaagctt gcccattttc aatacgtgct
     3121 agctgacgaa tcgtcaactc tgattcatca ccacaaatat ctatctgagt ttttccacaa
     3181 gatcgcctaa tagttttgat tttataacca atttcacgtt tcaactcatc catagtaata
     3241 ctccttaagt tgattacaaa gatttctttt tcttcctaat tcttttgtca atcatatata
     3301 aaacgataag cgaaaacagc ggtagaacaa tataactctt ttcactcatt atcagctgaa
     3361 atcccagggt tgctagtatc ttaaagatga aaatattcat caaaaataga aaaacaaata
     3421 ctaaaaaata ttttaaaacc ttcttcattt cttttcttca actttcctaa tttctacacc
     3481 tattttatcg aaaatatata taaaactcca aataaacact tcgactgcac tttttttggc
     3541 aaaaaataga cagaacaaac atcctaccta ctaaaaatat gatatgaaag gaaaatgatt
     3601 ttttactgac accctaggca agcttgggac aaataaatca ttgatagcaa catttacgac
     3661 atcctattta aagttccttc aatttctaat gtccccgcta tttctaagcc acctctggta
     3721 tgatctattc ctagtcagaa tagataacac cgttctaaat tacgattcat agttactcct
     3781 tttttgactc gttactataa gactcctatt tacatgcgca aaataatttt gattcagatt
     3841 catcatttat agttttgatt attttttaac agatttttct gttttcttct ccgaagactt
     3901 taaaaatttt tttctaatta aatcatccat ataaggacca aatataccaa ctactaaacc
     3961 aataataaaa cttttaaaat ccataattac caccaacatg tcgctgcata ggccacacct
     4021 ccaagtatag ctcctcccac agcaccagtt gctgcacctt gccatgttct tgttttaatt
     4081 cctagctgaa gacctcgtac tgctcctcct ccaacacctg ctttggcaaa atctccccaa
     4141 ttgcatccgc caccttcaac gcaagcaagc atctcagtat ccataatttc aaattgtgac
     4201 atcttttttg tattcataac gaatacctct tttttatttt taatatttgt cttgttacaa
     4261 acttgacaag tttagtataa cagtatctat taattttttt catccaaatc ttgaattggc
     4321 atcgaaacgt cttgaattag cttttttgtt tcaaaatcat ctctattttt aaaaaagatg
     4381 ttttctaatc acttttttac tattagactt cctgcaaaac tagaatccta gttcatgatt
     4441 gataatacca gcaatcaaat tcattcgtaa tccgaagcgt ttacgatgat ttcgataggt
     4501 tgttgaaaac attttaaacg tttttacttt ggcaaagata ttctcaacct tgcttctctc
     4561 cttagatagc gcatgattac aggctttatc ttcaactgtt agcggcttga gtttgcttga
     4621 tttacgtgga gtttgtgctt gaggatatat cttcatgagc ccttgataac cactgtcagc
     4681 caagattttt ccagcttgtc cgatatttct catttctaaa aaccatctac ttccgttgac
     4741 ttggaactcc gattgctatt ttccttgaat gattttaacc acatctccta cgttttggag
     4801 ttggtcaatt tcttcatcgc tgatttcgat actaaattca tcttccagag tcaagataaa
     4861 ctccatcaag tcaacagaat ccgcatccaa atcgtctttc agactcaagg attctgtcac
     4921 gacaaagtcc tctccctgtc gctcttggat aatggtcaca atacggtcaa aaatttcttt
     4981 ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag tctgggcaac cacgtctgtt
     5041 tctagcatgg tacggatctg acgaatcgta ctataaacag ccttggcatc gcttgagcca
     5101 tgagtcttga caacaggtgc cttaacacca aacaagaccg ctccaccaac atctgaataa
     5161 ttgagctgtt ttttcaaacc tctgaggctg tccttgagaa ggagggcacc tagtttcgct
     5221 cgaagaccac cacctgtaat agctgtcttg agcaagccca tgattcccat agctgtccct
     5281 tcgatggatt tgagcacagc gtttcccgtg aaaccatctg ccacaacaac atctgcaacg
     5341 ccattcatca aatcacgcgc ttccacgttt ccgataaagt tcaaactttc atcagccgcc
     5401 agtaattcat aagtttcctt acgaagcggg tcgcccttgc tactctctgt tccgttgttg
     5461 agcaaaccaa cgcgtggttg cgcaatgcca cggacatttt tagcatagaa ggaacctaga
     5521 accgcatatt gatggaggtg ctgggctgta ttttctgcat tggcaccaag gtctagcatg
     5581 tcaaaacctt ttccatcaac ggtaggcaag gtagacatga gtccaggacg gtcgatattc
     5641 ttgatacgac ccacgacgaa gaatcctgct gccaacaagg cacctgtatt cccagccgaa
     5701 aggacagcgt ctgcttcacc atctttgaca gccttggctg ccaataccat actggcattt
     5761 ttcttattcc taatagctct cgtaggttca tcatccgaat caatcttctc atccgtatgg
     5821 ataatgctga cgcgctctgt cgctgtcaga tattgcttga ttttagcttc atctccgtaa
     5881 agttgaacct cgatatctga aaagtcagat agggcttgat tgacaccctc aacaatggcc
     5941 tgaggtgcgt aatcgccccc catggcatct actgcgattt ttttcatttc ttttcctctt
     6001 ttagtaattg tccccagtct gctagggaat caataaattt ctttgatttt aggtgaatcc
     6061 caacgtactc ttcatataat tgatccataa attggcgtag ctcttgcttg attccaggct
     6121 tgagcgaaat ggtctccaaa gtctcaaaat caatagcttg aaattgattg agcagatagg
     6181 ggatattggg attgagatga caacgtctct tatcctcatg ataatgctct ggacagaggc
     6241 aggctccata tttgaaagaa aagtcaaaag cctgaccaac ccgatggcag aagacacact
     6301 cattaaaatt gaggctgatt ccaaatcgag tcaaaatttg aatttcaaaa atattggtca
     6361 aaacctgata atccaagcct gcttccatca actccaaagt cttttgcaaa aaagcaaaca
     6421 agggagcatc ctgctgattg tcctgcaaac tagcatctgc aagagctgcc acataggtcg
     6481 cataggccat gacaaagagg tcactattaa tcttgggaaa agtcatgacc tcatgatagt
     6541 cttcgatgta actgagtccg tcatcattga ttcgcaagag aaatcgtgcc agcaccaagg
     6601 gctgaataac aggcgccagc ttagactgac cagcgtgttt gacaaaaaac atgcgtttgc
     6661 caacctgctc tgtaaaaatt ttgacgagct tgtcatcctc acgaaaattg cgattgtaaa
     6721 gcaccaagcc ttgactcgtg atagactgaa tcatgcttct ctcatgtact cctcaagtcg
     6781 tttcatggct tctttgatag tctccatgct ggctgcataa gataggcgga cgtagccttc
     6841 cccgtaacgt ccaaaggctg caccagggat aaaggcaacg gccttcttct gagcaaaatc
     6901 cttcagaaaa gcaaaggagt cttgattgta gcccgctgga attttagcaa aaatatagaa
     6961 ggcaccgtct ggtttgataa tctcaaaacc aagagcagtc attttttcga tgatatagtc
     7021 ccgacgctgg atatattcct tcttcatggg ctccgcatca tttttaccag ccgtcaaggc
     7081 ttctaccgca gcatgttgcg ccatggtatt tgcggcagtg accaagtact ggtgactctt
     7141 gattaactgg gctgtgaagg tcgcaggagc gaaaatcagc cccaaacgcc aacctgtcat
     7201 ggcatgcgat ttagacaaac cattgataat aatagcctgg tctctcaaca tcgttcctag
     7261 agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa acctcatcac agacaacaaa
     7321 aacttcgtac ttgcgtaaaa cagctgccaa ggcctctaac tgctctcgac tgtaggtaat
     7381 tcctgtcgga ttggctggat agttgagaat aaccgccttg agcttatcac cctgctccaa
     7441 aatggccttc tccaacatct caggagtcaa gacaaaacca ttttcagtcg tatcaatctc
     7501 aacaatttct gccccaacta agttaacaat cggttcataa cccggataag caggagctgg
     7561 caaaagtacc ttgtctccct cttccaaaat agccgtcaaa gtcgcagata aagcctctgt
     7621 cgccccaatt gtaaccaaga tttcattttc aggagcatag tccagttggt acttttcctt
     7681 aacaaagtca ctggctgcct gacgtagagt cagcagacca ctcatccctg tatagtagga
     7741 ttggttctga tcaatcgctc gcttggccgc ctccttgaca tggtctggcg ttgtaaaatc
     7801 aggttccccc aaggtcaaac gcaagacccc aggaatctcc gaaataacct ggtcaaactg
     7861 acgaatcaac gaaacttgaa ttttatctaa ctgtttatta aagcgcttag ttaagtccat
     7921 agatacctcc tactttcaaa acgtatctct attatactac aaaagccccc cgaccgcaaa
     7981 aatacattag agaatagctt tccactttct attttacttt tcctgtttat aggtctataa
     8041 tggtaacaga ttctatttgg aggtttttat gtcatttcta tcaaaaaatg gagcaggtat
     8101 cttggcctgc cttctcattt ccatcctatc ttggtactta ggaggattct tccctgtgat
     8161 tggcgcgccc gtttttgcca ttttcatagg catgctccta catccctttc tctcgtccta
     8221 taaacaactg gatgctggtt tgacctttag ttccaagaag ttgctccaat atgccgttgt
     8281 cttgcttggt tttggtctca atatctcgca ggtcttcgca gttggccaat cttcactccc
     8341 tgtcatcctg tccactatct caatagctct gattattgcc tacctcttcc agcgtttctt
     8401 tgcactggat acaaaactgg ctaccttggt tggagtaggt tcttctatct gtgggggttc
     8461 tgccattgca gcgacagcgc ctgttatcca tgctaaggaa aaggaagtag cccaagccat
     8521 ttccgttatc tttttcttca atgtcttggc tgcgctcatc tttccaaccc tcggcacctg
     8581 gcttcatcta tccaatgaag gcttcgccct ctttgcaggg actgcggtca acgacacttc
     8641 ctctgtaacg gctgccgcca gcgcttggga cagtctttac caaagcaata ccctcgagtc
     8701 tgcaaccatt gttaaactca cacgtacttt ggccattatc cctatcacgc tctttctatc
     8761 ctactggcaa agtcgccaac aagaaaacaa gcaaagccta caactgaaaa aagtcttccc
     8821 actttttatc ctttacttta tccttgcctc tctcctcact acactactca cctctctagg
     8881 tgtgtccagt agtttcttta cccctctcaa acaactctct aaattcctta ttgtcatggc
     8941 catgagtgct atcggtctca aaaccaatct ggtcgctatg gtcaaatcca gtggaaaatc
     9001 cattcttctt ggagccatct gctggattgc catcatcctc accactcttg gtatgcagac
     9061 ccttatcggc attttctaac actcttcgaa aatctcttca aaccacgtca acgtcgcctt
     9121 gccgtatata tgttactgac ttcgtcagtt ctatctacaa cctcaaaacg gtgttttgag
     9181 ctgacttcgt cagttctatc tacaacctca aaacggtgtt ttgagctgac ttcgtcagtt
     9241 ctatctacaa cctcaaaacg gtgttttgag ctgacttcgt cagtcgtatc tacaacctca
     9301 aaacagtgtt ttgagcaacc cgcagctagt ttcctagttt gctctttgat tttcattgag
     9361 tataacacaa aaggtagccc atcagctacc tttttcttat gcttcctcaa tcaagcgagt
     9421 atgttctctc ttgatacagc gattcatcac gatatcatca catccaccat cacgcaaaat
     9481 ctctttcgct tctaaacttt caagtcctag ctgtgcccaa aaaatcttgg catcagcttt
     9541 gagaaaatca cgcgccacat cgggcagaaa ttcactgcga cgataaacat tgacaatatc
     9601 tacaggaaaa ggaatttcag cgaggctagc ataagccttt tcacccaaga tttcgccacc
     9661 tgccgccttg ggattgactg ggatgatttt atagccccga gcctgcattt cctttgttac
     9721 tcgattgctg gttgtttctt cacggtcaga caaacccacc acagcaaggg ttttactcgt
     9781 tgcgagatac tgacgaatca caccatcact tggattgata aattcttgac tcatagaaaa
     9841 cctccttttt catcagtata gcacattttg aaaaggtttg cagaattcta ctacaaaaaa
     9901 ggaggactag cccccttttt atttagcctc gtaccaggtt gccccttcat tctcatctgc
     9961 gataagagga acactgagtt gaatggcttc ttccatggtt tgtttcacca atttttttat
    10021 ctctaccaat tcagatttag gcacttcaag gacgatttca tcgtgcactt gtaacagcat
    10081 cttagtctga taaccacctg caaccaaggc tttatccagc tgaatcatgg caatcttgag
    10141 aatatctgct gccgaaccct ggataggtga gttgatagca gttcgctccg caaaaccacg
    10201 aatattgaag ttgcgcgaat tgatatctgg caactcacgg cgacgcttaa agagggtctc
    10261 tacatagccc ttatcacgcg cctcccgcac cacttcatcc atgtagtttt taatacctgg
    10321 aaaacgttca aagtaggtat caatgtaggc tttggcttcc ttacgactaa ttcccaaatt
    10381 attagacaag ccaaagtctg aaatcccata aaccactcca aagttaactg ccttggcatt
    10441 gcgacggtca tttgcagtca cattatcagg acgctcaatg ccaaagaccc gcatggctgt
    10501 cgaagtatgg atatctgccc cctcttggaa ggccttaatc aagtgctcat ccttagaaat
    10561 atgcgccaaa acgcgcaatt caatctgtga atagtcagag ctgagtagca cactatcctc
    10621 ccactctggc acaaaagcct tccgaatcaa gcgcccttgt tccaatcggg caggaatatt
    10681 ttgcaagttt ggatccacac tagacaaacg cccggtctgg gtcaaatcct gcacatagcg
    10741 agtatgaatc tttccatcag ccaaaatcca gtcctgcaag ccaattacat aagtagattg
    10801 aatcttagca atttgacggt aatccaggat tttcttaaca atcggagcaa taggagcgag
    10861 acgctccaaa acatccactg ctgtcgaata acctgtcttg gttttcttag tgtattctag
    10921 aggaagtccc aatttctcaa agagaagcac gcccaactgc ttaggcgagt tgacattaaa
    10981 ctcctcaccg gccagctcgt aaatctcttg agtcagtttt tcaatgacaa gctcattttc
    11041 agcctgcatc tcaagcaagg tctctttctt gaccataatc ccagcaattt ccatcttggc
    11101 aaggacaaaa gccagaggtt gctccatatc ataaagaagc tctaattgcc cattttcgct
    11161 gagtttttca agtaaaatag gctctgtttc taccaaaaca gcaagtttac aagctaagtg
    11221 ttccaagaat ttctcacgtt caggaatggc ctttttaaca cccttaccgt agaaagtttc
    11281 atcatcaacc aagtaagtct gaccataaag actagcgatg gtcgcaattt cattgtcctc
    11341 cacagtcgaa aggaggtatt tagccaaacg gatgtcaaaa gcaggcgcct gcaaatctac
    11401 accaaaacgt tgcaaaagaa ctttaacctt cttaaagtca taaactctca gagatgtttt
    11461 ttctaagaaa tccttgaaaa tcgggtcttg caacagctca agcttgtctg tggcatagag
    11521 ctgatcccca caagaccagg caaatccaac caaattatct gtatggtaat tctcaccaaa
    11581 aagctcaaag tggaagatag actcttcact cagcatatct tgactgattt ggtcaacaat
    11641 agtaaaatcc aaaccctcag ccacatcagc tgacgacaca tttaaagcct gcttgagctg
    11701 tttgaagccc atctcatcgt aaaatttccc aagattttca acatctggac cactatagac
    11761 caagtcctct aaaccaatcg caatcggtgc cttggtatca atggtcgcta gtgttttaga
    11821 caaaaaggcc tgttccttgt cattgatgag attttccttc atcttagaag tcttcattcc
    11881 atcaatattt tcataaatcc cctcaagcga accatgctcc agcaagagct taatacccgt
    11941 cttttcaccg actttggtca ccccagggat attatccgac ttatcaccca tgagcgcctt
    12001 gagatcgata aactgagctg gtgtgaggcc catttcttcc atgaggtaat ctggcgtaaa
    12061 ggcctcaaac tcagccacac ctttcttgga aatttcaacc accgtatgct catccgtcag
    12121 ctgaatcaaa tccttgtccc cactgacaat ggtaatatca aaaccatcct gctctgctag
    12181 cttatccagc gtcccaatga tgtcatccgc ctcatactga gccagctcat agtgacgaat
    12241 ccccatatga tccagcaact cacgaatgaa aggaaattgc tcacgaaact catcaggagt
    12301 cttggcccga ccacccttat agtccgcata catctctgtc cggaaggtcg tctttcccgc
    12361 atcaaaagcc accaaaatat gactcggctc aacccgctcc aacaaatgac tcaacatcaa
    12421 ctgaaaacca taaatcgcat tggtatgcaa accagccgca ttcttaaaac ggtccaactg
    12481 ctgatacagc gcaaaaaacg cccgaaaagc tacagaagac ccatcaatca ataataattt
    12541 tttcttatcc atacacccat tataaaggaa agaatcaaaa aataccattg ggaagagcta
    12601 gagcaagtat ttttcaaact ttttccgaat aaatagatag agccagagaa tttagtaaac
    12661 ctagatttaa aaatgtgcta taatatagta tattgaatct ataa
//
LOCUS       DAVLTG010000049        12544 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLTG010000049 DAVLTG010000000
VERSION     DAVLTG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.050"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..333
                     /locus_tag="VYN12_001653"
     CDS             <1..333
                     /locus_tag="VYN12_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1415988.1"
                     /translation="SWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYY
                     LNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYYVNGLGALAVNTTVDGYT
                     VNENGEWV"
     gene            733..1854
                     /gene="mnmA"
                     /locus_tag="VYN12_001654"
     CDS             733..1854
                     /gene="mnmA"
                     /locus_tag="VYN12_001654"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1415989.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTTLLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1995..2450
                     /locus_tag="VYN12_001655"
     CDS             1995..2450
                     /locus_tag="VYN12_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1415990.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGFSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKFEDIQLVPAFLKTALPDWEGQLRHIHREE"
     gene            2460..4373
                     /gene="mnmG"
                     /locus_tag="VYN12_001656"
     CDS             2460..4373
                     /gene="mnmG"
                     /locus_tag="VYN12_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1415991.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDKILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDAVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4562..4651
                     /locus_tag="VYN12_001657"
                     /pseudo
     CDS             4562..4651
                     /locus_tag="VYN12_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4752..6431)
                     /locus_tag="VYN12_001658"
     CDS             complement(4752..6431)
                     /locus_tag="VYN12_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1415992.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6433..6666)
                     /locus_tag="VYN12_001659"
     CDS             complement(6433..6666)
                     /locus_tag="VYN12_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1415993.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7048..7269
                     /locus_tag="VYN12_001660"
     CDS             7048..7269
                     /locus_tag="VYN12_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1415994.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7482..7634)
                     /gene="cibB"
                     /locus_tag="VYN12_001661"
     CDS             complement(7482..7634)
                     /gene="cibB"
                     /locus_tag="VYN12_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1415995.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7636..7821)
                     /gene="cibA"
                     /locus_tag="VYN12_001662"
     CDS             complement(7636..7821)
                     /gene="cibA"
                     /locus_tag="VYN12_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1415996.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7999..8682
                     /gene="tsaB"
                     /locus_tag="VYN12_001663"
     CDS             7999..8682
                     /gene="tsaB"
                     /locus_tag="VYN12_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1415997.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8679..9116
                     /gene="rimI"
                     /locus_tag="VYN12_001664"
     CDS             8679..9116
                     /gene="rimI"
                     /locus_tag="VYN12_001664"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1415998.1"
                     /translation="MIEIKRIQKHSDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9106..10116
                     /gene="tsaD"
                     /locus_tag="VYN12_001665"
     CDS             9106..10116
                     /gene="tsaD"
                     /locus_tag="VYN12_001665"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1415999.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10156..11462)
                     /locus_tag="VYN12_001666"
                     /pseudo
     CDS             complement(10156..11462)
                     /locus_tag="VYN12_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11795..12089)
                     /locus_tag="VYN12_001667"
                     /pseudo
     CDS             complement(11795..12089)
                     /locus_tag="VYN12_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12196..12489)
                     /locus_tag="VYN12_001668"
                     /pseudo
     CDS             complement(12196..12489)
                     /locus_tag="VYN12_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3555 a         2505 c         2939 g         3545 t
ORIGIN      
        1 tcatggtact acctcaacag caatggcgct atggcgacag gttggctcca atacaatggt
       61 tcatggtact atctaaacgc taacggcgct atggcaacag gttgggctaa agtcaacggt
      121 tcatggtact acctcaacgc taacggttca atggcaacag gttgggtgaa agatggagat
      181 acctggtact atcttgaagc atcaggtgct atgaaagcaa accaatggtt caaagtatca
      241 gataaatggt actatgtcaa tggcttaggt gcccttgcag tcaacacaac tgtagacgga
      301 tatactgtca atgaaaacgg tgaatgggtt taagccgatt aaattaaatc atgttaagaa
      361 catttgacat tttaattttg aaacaaagat aaggttcgat tgaatagatt tatgttcgta
      421 ttctttaggt acctgtctta tgatttcagg aaatgtcatt aaaaaaacga ctccttttct
      481 ctaacttgga aaatagatta gagaaaatgg gttgttttat ttattatagt tatttgaatg
      541 aagataagaa gaaggtatac tcacatcatt cacaaatctg tatattgact ataagtttta
      601 aaaaacaatt tttaagctct tccttgtctt ctctaaccaa gcgtgttata atgaatactg
      661 ctcaagcgac cttcaatcgt gaagcacaca cgaccttcaa tcgtgaataa acgaatagat
      721 gggagactta ccatgagtga taactctaaa acacgtgttg tcgtggggat gagtggtggt
      781 gttgattcgt cggtgacgac tcttcttctc aaggagcagg gctacgatgt gatcggtatc
      841 ttcatgaaga actgggatga cacagatgaa aacggcgtct gtacggcgac cgaagattac
      901 aaggatgtgg ttgcggtggc agaccagatt ggcattccct actactctgt caattttgaa
      961 aaagagtact gggaccgcgt ttttgagtat ttcctagcgg aataccgtgc gggacgcacg
     1021 ccaaatccgg acgttatgtg caacaaggaa atcaagttca aggccttttt ggactatgct
     1081 atgaccttgg gggcagacta tgtagcgact gggcattatg ctcgagtggt gcgtgatgag
     1141 gatggcactg ttcacatgct tcgtggcgtg gacaatggca aggaccagac ctatttcctc
     1201 agccaacttt cgcaagaaca acttcaaaaa accatgttcc cactaggaca tttgaaaaag
     1261 cctgaagttc gaaaactagc agaagaagca ggtctttcga ctgctaagaa gaaagactcg
     1321 acagggattt gctttatcgg agaaaagaac tttaaaaact tcctcagcaa ctacctgcca
     1381 gctcagcctg gtcgcatgat gactgtggat ggtcgcgata tgggcgagca tgcaggtctt
     1441 atgtactata cgattggtca gcgtggcggg cttggtatcg gtggacaaca cggtggtgac
     1501 aacgcgccgt ggttcgttgt cggaaaagac ctgagcaaga atattctcta tgtaggccaa
     1561 ggtttctacc atgattcgct catgtcaact agcctagagg ctagccaagt ccactttact
     1621 cgtgatatgc ccgaggagtt tacgctagaa tgtacggcta aattccgtta ccgtcagcct
     1681 gactctaagg tgaccgtcca tgtcaaagga gacaaggcag aagttatctt tgcggaacca
     1741 caacgcgcga ttacaccagg acaggcagtt gtcttttacg atggcgaaga gtgtctaggt
     1801 ggcggtttga ttgacaatgc ttaccgcgat ggacaagttt gtcagtacat ttagattgac
     1861 aaattttctc aatttgctac aataataaca gcaatagaaa tgatggtcaa agctcatgga
     1921 tgttgcaggc ttttttgtcc tgcacttctt tggagttttg actgtttttg tgtcgtttaa
     1981 gggaaaggac aagaatgact caacaagact ttcggacaaa agtagacaat acggtttttg
     2041 gtgttcgggc gacagctttg attcttcaaa atcgcaagct tctagtcacc aaagacaagg
     2101 gcaagtatta cactatcggc ggtgcgattc aagttaacga aaaaacggaa gacgcggtag
     2161 tccgtgaagt gaaggaagaa ctgggtgtca aagctcaagc tgggcagcta gcttttgtgg
     2221 ttgaaaatcg ttttgaacag gacggttttt cctatcacaa tatcgaattt cattatctgg
     2281 tggacttgct ggaggatgcc ccattgacca tgcaggaaga tgagaaaagg cagccctgtg
     2341 agtggattga cttggataag tttgaggata tccagctagt tccagccttt ttaaaaacgg
     2401 ccctaccaga ttgggaaggc caactaagac acattcatcg tgaggaatag gagagaaaca
     2461 tgacttatca ttttactgaa gaatacgata ttattgtaat tggtgcggga cacgctgggg
     2521 ttgaggcttc cttggccgct agccgtatgg gctgtaaggt tctacttgcg accatcaata
     2581 ttgaaatgct ggctttcatg ccttgtaatc cctctatcgg tggttctgct aaggggattg
     2641 tcgtacgtga agtcgatgcc ctcggtggcg agatggccaa gaccattgac aagacttaca
     2701 tccagatgaa gatgctcaac acagggaagg gtcctgctgt tcgtgccctt cgtgcgcagg
     2761 ctgacaagga actttactct aaggagatgc gcaagacagt tgaaaatcaa gaaaatctga
     2821 cccttcgtca aaccatgatt gataagattt tggtggaaga tggcaaggtt gtcggtgttc
     2881 gtacagcgac tcatcaagag tatgctgcta aggctgttat tgtgacgaca gggactgctc
     2941 tccgtgggga aattatcatc ggagacctca agtactcatc aggtcctaac cacagcttgg
     3001 cttctattaa cctagctgac aatctcaagg aactgggtct cgaaatcggt cgtttcaaga
     3061 caggaacccc tccacgtgtc aaggcctctt ctatcaacta cgacgtgaca gaaatccaac
     3121 caggagacgc agtacctaat catttctcat acacttcacg tgatgaggat tatgtcaaag
     3181 atcaagtgcc atgctggttg acctatacca atggtaccag tcatgagatt attcaaaaca
     3241 acctccaccg tgcgcctatg tttacaggtg tggtcaaggg agtggggcct cgttactgtc
     3301 cgtcgattga agacaagatt gtgcgctttg cggacaagga acgtcaccaa ctcttccttg
     3361 agccagaagg gcgcaatact gaggaagtct atgttcaagg actttcaacc agtctgcctg
     3421 aggatgtcca gcgtgacttg gttcattcca tcaaaggttt ggaaaatgca gagatgatgc
     3481 ggacaggtta tgctattgag tatgatatgg tcttgcctca tcagttgcgt gcgactttgg
     3541 aaaccaagaa aatctcaggt ctcttcactg ctggtcagac aaatggaacg tcaggttacg
     3601 aagaggcagc aggccaaggg attatcgcag gtatcaatgc ggctctaaaa atccaaggca
     3661 agcctgaatt gattctaaaa cgaagtgacg gttatatcgg ggtgatgatc gacgacttgg
     3721 tgaccaaggg aaccattgaa ccttaccgtc tcttgaccag tcgtgctgaa tatcgtctca
     3781 ttcttcgcca tgacaatgct gatatgcgct tgactgagat gggccgtgag attggccttg
     3841 tggacgatga acgctgggct cgttttgaaa tcaagaaaaa tcaatttgat aatgagatga
     3901 aacgcctaga cagtatcaaa ctcaagccag tcaaggaaac caatgctaag gttgaggaaa
     3961 tgggcttcaa gccgttgaca gatgcggtga cagccaagga attccttcgc cgtccagaag
     4021 tttcttacca agatgtggtg gccttcatcg gaccagctgc agaggaatta gatgacaaga
     4081 ttatcgaatt gattgaaaca gaaatcaagt acgaaggcta tatttccaaa gccatggatc
     4141 aggttgccaa gatgaaacgt atggaagaaa aacgcattcc agccaatatc gactgggatg
     4201 acatcgattc tattgcgacg gaagctcgtc agaagttcaa actcatcaat ccagaaacca
     4261 tcggccaagc cagccgtatt tcgggagtaa acccagcaga tatttctatt ttgatggtgt
     4321 atctggaagg taaaaatcgt agtatttcta aaactcttca aaaatcaaaa tgatacgtcg
     4381 taggcttctt acgaatgagt tcaaagcttg gctttgattc atctccaacc tcccatagtt
     4441 ccccgaacta tgggagctaa ctcaagttat gcattttcct agccttctgg tctgattttc
     4501 attgagtttt aatctaaaaa gaaagcatag agaaaaacag ctccgaagac ggggctgttt
     4561 tgttgatttg tactcaatga aaatcaaaga gcaaactagg aagctagccg taggttgctc
     4621 aaagcactgc tttgaggttg tggatagaac tgacgaagtc agctcaaaac accgttttga
     4681 ggttgtggat agaactgacg aagtcagtaa catatatacg gcaaggcgaa gctgacgtgg
     4741 tttgaagagt attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt
     4801 tcggtatttt catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc
     4861 acgctagcat ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt
     4921 tgacgaatca agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga
     4981 ccagatagaa tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct
     5041 tcagatagat cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca
     5101 tcgacataga tatcttgggc gttgaaatgg cctgcgatac gagctgagtc agcagtaagg
     5161 gcaagcacat cgccattgct catgataaag atattgtcct tctcaacacc agtatccact
     5221 gctagtccag cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt
     5281 ggcttaatca agcagagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg
     5341 atattgttca ctttaccgtg gataacttcg acaccagctt cagaaatgat gttaatcagc
     5401 ttgttgacgc tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcacct
     5461 ggttgtaatt gtacttgacg gtgggttccg ttggcgatac gagagagggc tgccataggc
     5521 tcaccctgac tacctgtaca gaggataaga acttctcctg caggataatc tttgatttca
     5581 tttggctcga taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca
     5641 atggcctttt ccatagaacg accaaagacc gcaatcttgc gtccagtctt aacagcagct
     5701 tctgttgcct gctggagacg gaagatattt gaggcaaagg atgcaaagat gatacgtcct
     5761 tcaatacctt ggataatctt cataatggac tgaccaacga ctttttcaga gttggtaaag
     5821 gttggtactt ccgcatttgt cgagtcagac aggagacaga gcacgccttc ttcaccaagc
     5881 gcagccatac gatgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca
     5941 cccgtacaga cgattttccc ttgaggagta tgaatgacaa tccccaaagg ctctggaata
     6001 gagtgagtcg ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg
     6061 ttgatttcgt aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc
     6121 aaagccaagg caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga
     6181 atcccaccaa tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata
     6241 ttgtctacga tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct
     6301 gggaatttaa tcccagcatc gacgatgata atctcgcctt ggtattcaat tccgtaagtg
     6361 tttttcccga tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga
     6421 gtgtaggcca tattagaact ccgtaatttc gaaggcgcca gtttcttttt cgtaatcgag
     6481 caatttgtca gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac
     6541 aagttggcga gcagtgatac ggccctcaag ttctgagctg gcatcgatgt ctaggtaaag
     6601 cgcgcgtgtt gtttcacggc gtgggctacg ttcttttgtt tcttgataaa aaactttgta
     6661 aatcatatag ttcctttcta tttacaggtc agcttattcc aaacttttag cagatatttg
     6721 cttgatttca ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta
     6781 taccacaaaa tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttc
     6841 ggtaagcgtt tgcgaaaata aagaaaatgt attatgttga taacggaagt gaaatttatt
     6901 gcttgtcata attccatata gattttaagt caaggaggtt gccctatgta taacttattt
     6961 gcttttgcta tcggagttcg tttgctagct tttatcgttt ttgttttgcg tttatggagg
     7021 aaatcttcta tttgccaaac tggaacgatg acaaaccaag ttcttgagga aaattacctt
     7081 tgtgactctc tactcgcttt ttctcctcct cgtgacctat gtcgtttggt ttgtatttta
     7141 ctttggatta aatgcttaga tgccctgctt atgctggggt tttttgtttg gggatgtaga
     7201 gatagtagat ttacgacacg aaaattccac cccatctatc aagatgaggt ggtctttgca
     7261 tttttctaaa atgatatgac aatggaattt tcaaagctta ttatttttat gggagtcatt
     7321 gttctgctca aaaatagagt tgaagcataa aaataaaaca atacaaacag ataaatcgaa
     7381 tggtaaaggg atggtagtaa tgttcaaatc attgagaatg ctgagcaaac tgtaagagat
     7441 gaagacaata aaatttatcc ttctaaaaat gtgtttctta tctagcatga cttaccaaac
     7501 tttttacgaa ggtcttttcc aatggtataa cctgccataa ataaagcgat accaacacct
     7561 acaccaaagc cacccttgat ttcttgcaat tccttattag aaatttcacg acagttgttc
     7621 aaatctttca tcatattaat ctcctcctaa aaaataacca gctgccaaac cagaacctat
     7681 aagtgctgtt ccacctgcaa tagctttcca agatactgct actccaaaga taaccaaggg
     7741 agcgagaccg ccatcaatat ctgataattc attttcagat aaggataaaa attgattgtc
     7801 aagaatgtca aaatttgtca ttgaactttc ctcctttttt cttgttcact tttatattcg
     7861 gaaaagaaaa ggaaaagtga gcattttttt aaattatttt tagttaagtg agggcactct
     7921 tgtctggggg caaagaaaat tcccatgtgc cagcttttgt agtataatag taagcagaca
     7981 aaaagatagg aatgtgttat gaaagtatta gcttttgata cgtccagcaa ggctctttct
     8041 ctcgctattt tagaggacaa gcaggttctt gccgagacga cgattaatat taagaaaaat
     8101 cacagtatta ctcttatgcc tgccatagat tttttgatgg caagtttgga ttggacaccc
     8161 aaggatttgg accgaatcgt ggtagctgaa gggccgggta gctacacagg cttgcgaatt
     8221 gcggtagcca ctgccaagac tttggctcat actctgaaca tcgagttagt tggtatgtct
     8281 agcctcttgg ctctggtacc ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg
     8341 cgtcgcaaca atgtttatgt aggattttat gaaaatgcta aacccgtcat gccagaagct
     8401 cacttaccct ttgagcgagt gattgagtta atcaagggtg ctagtcaggt tacctttgtc
     8461 ggagaagttg gcccctttgt tgagcagatt caagaatact tgccaaggac taatttcaaa
     8521 gaaaccttgc caaatgcagc taatctagct ctatgggcct gggacaagga agcagactcc
     8581 ttgcatgatt ttgtgccgaa ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag
     8641 aatcacaccg agtctggcga gtcttacatt aaacgcttat gatagaaatc aaacgaatcc
     8701 aaaaacattc tgacttggct caagccatct acgctgttat gatagctgtt tacccagtca
     8761 gtccttggac gctggaacaa atccaagcag acctgtccca agaccaaact tggtatgctt
     8821 tggcttatga tggggcagaa gtgattggat ttctagctgt gcaggagaat ctttttgaag
     8881 cagaagtcct gcaaatcgct gtcaaaggag cttatcaggg tcagggaatt gcgtcagcct
     8941 tgtttgctca attgccgaca gacaaggaaa ttttcctcga agtcagacag tcaaatcaac
     9001 gagcgcaagc attttacaag aaagaaaaga tggcagttat cgctgagcga aaggcctact
     9061 accatgaccc agtcgaggac gccattatca tgaagagaga aatagatgaa ggatagatat
     9121 attttagcat ttgagacatc ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat
     9181 gagctcttgt ccaatgtcat tgctagtcaa attgagagtc acaaacgttt tggtggcgta
     9241 gtgcccgaag tagccagtcg tcaccatgtc gaggtcatta cagcctgtat cgaggaggca
     9301 ttggcagaag cagggattac cgaagaggac gtgacagctg ttgcggttac ctacggacca
     9361 ggcttggtcg gagccttgct agttggtttg tcagctgcca aggcctttgc ttgggctcac
     9421 ggacttccac tgattcctgt taatcacatg gctgggcacc tcatggcagc tcagagtgtg
     9481 gagcctttgg agtttccctt gctagccctt ttagtcagtg gtgggcacac agagttggtc
     9541 tatgtttctg aggctggcga ttacaagatt gttggggaga cacgagacga tgcagttggg
     9601 gaggcttatg acaaggtcgg tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt
     9661 gacgagctgg ctcatcaggg gcaggatatt tatgatttcc cccgtgccat gattaaggaa
     9721 gataatctgg agttctcctt ctcaggtttg aaatctgcct ttatcaatct tcatcacaat
     9781 gccgagcaaa agggagaaag cctgtctaca gaagatttgt gtgcttcctt ccaagcagca
     9841 gttatggaca ttctcatggc aaaaaccaag aaggctttgg agaaatatcc tgttaaaacc
     9901 ctagttgtgg caggtggtgt ggcagccaat aaaggtctca gagaacgcct agcagccgaa
     9961 atcacagatg tcaaggttat catcccccct ctgcgactct gcggagacaa tgcaggtatg
    10021 attgcctatg ccagcgtcag cgagtggaac aaagaaaact tcgcaggctg ggacctcaat
    10081 gccaaaccaa gtcttgcctt tgataccatg gaataaagag tggctctttg tcaagtgtag
    10141 tgggtaggcg aaaagctaca atctggagag tacgaaattc gtactctctt ttttgatgtt
    10201 caaagtcatc aaaatccgtt ttttaaaatt gttaaagttc cgaaaaccaa aggctttgcg
    10261 cttgataacc ttaataaaat tattggtcgc ttcaagttta gcgttggaat aaggcagctt
    10321 aagtgcgttg ataatcttat ctctatccct taaaaaagtc caaaagaccg tttgaaaaag
    10381 cggatgaacc gttggcagtt cttgctcaat caatccaaag aaatggttgg cattcttctc
    10441 ttgaaaatga aagagcagga gttgatagag ttcgtagtga acctgtaatc cctcagagta
    10501 agaaagcagc ttatctcgta cttcccgatg ggttaagtgc attcgaaacg tgggctgata
    10561 gaatcgtttc tgacagagct tgaagctatc ctggtgtagt aaatcagtcc agtggactga
    10621 tttagcccga gcctagaaac gaaaaagcga gggttccaaa agcgcttgag cgcccgatac
    10681 tccaaggatt ttcggtcaaa ttggttcatg atttggattc gtactcggtt catagctcgg
    10741 ctcagatgtt ggacaatgtg gaggcggtca agaacaatct tcgcctttgg aaagagttgc
    10801 ttagcgagcc gataataagg gctgtacatg tccatggtga tgacctcgac cagctcccga
    10861 acctctctct gatagcgttg gaaatggttt cgaatcaccg catgagttcg cccgtctaaa
    10921 attgcgagga tggatttgga ctcaaaatct tgggcaatga agctcatttt gctctttttg
    10981 aagctatact catcccaact cataactttt ggcaacttgg tccaatcggt ttcaaactta
    11041 aattccctca gttttcggat gacggtggaa gttgagaccg ccaatctgtg ggcaatctca
    11101 gtcatagact gcttttcaag gaggagctga gcgatttttt gtctcaccat gttggaaatc
    11161 tggcaatttt tcttgacaat ggatgtttga gaaacgacca ccttaaggca attcttgcac
    11221 tgaaagcggc gctttttgag atgcagtacc gtgggtaaaa cctgacagtc gagaagcgga
    11281 attttagagg ctttctggaa gtcgtatttg atcatcttcc cttgacaatg aggacaagga
    11341 ggagcggggg aatccaactt tgcctgaacg actagatggg tttggtattt cagaacagac
    11401 aagattttga tatttttgtc ttccaatccg agcaaatctg tggtattctt aagttgttcc
    11461 atatgaaccc tttctaatga gttggttaga cgcttttcat tataggtcat atggggcttt
    11521 ttttctacaa gaaacgaccc tataattcct ggggtgggat tacccactac agaaattata
    11581 gagccaaagc attccaaagt cttgtctgac tctggaatgt tttctgttca cagttgtttt
    11641 gtaactgcct aataagtaac cgcgctataa cgaggtatct accgagattg tcaattctcc
    11701 agtatactgt tataaaaaac aaaactggag gattttttta tgtcccccca tcgtcccatc
    11761 gactgttccg tagctgccca ataacggagt ataatcagct gaaacaagaa taggacaaaa
    11821 gtgcctcaag aaaagcatcg taatttgaca atattattct gagatgtttt tgatgtaagc
    11881 ccatattttc tcaatgggat tatactcggg tgaatagata ggaagtggta acagtctatg
    11941 ccctgctcct tacacatgtt cattctgtga aaccttgcat tgtccataat gataagggat
    12001 ggtgtatcta aagtaggtag taagaatttt tggaagcaag cttcgaaaaa gtcactcgtc
    12061 atcgtatctt tataggtcat cggagccata gtatattgaa acaaaaaagg gcattagtac
    12121 ttctataaca gtatcgcaat ctctggtgtg cgttgtctcg atcttaattc aaataattat
    12181 atcttcttcc agagagacta actgcctgct caaggctcga tcatattcga gataaaaata
    12241 ggtcttaacc cctgtctcat aaatataaat aggagtcagg tagcttaagt gattcaattc
    12301 tttaaggaac cgatttactt tttctgggtc ttgttcgcag taggtacggc tcttttttag
    12361 actatatccc atagccttta gagcgtaatg aatagttgtt ggaggacagt tgaattcagc
    12421 agctatttca gtcaaataag catcgggatg agtttcaata tagatcttta atttatctct
    12481 atcaactttt tcaattaata gtggaagttt tcttaaagtt agtgtattga aacgttttta
    12541 taca
//
LOCUS       DAVLTG010000050        12438 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLTG010000050 DAVLTG010000000
VERSION     DAVLTG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.051"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            66..335
                     /gene="blpJ"
                     /locus_tag="VYN12_001669"
     CDS             66..335
                     /gene="blpJ"
                     /locus_tag="VYN12_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1416000.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            404..652
                     /gene="blpK"
                     /locus_tag="VYN12_001670"
     CDS             404..652
                     /gene="blpK"
                     /locus_tag="VYN12_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEV1416001.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            896..1045
                     /gene="blpO"
                     /locus_tag="VYN12_001671"
     CDS             896..1045
                     /gene="blpO"
                     /locus_tag="VYN12_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1416002.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1149..1268
                     /locus_tag="VYN12_001672"
     CDS             1149..1268
                     /locus_tag="VYN12_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1416003.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1736..2107
                     /locus_tag="VYN12_001673"
     CDS             1736..2107
                     /locus_tag="VYN12_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416004.1"
                     /translation="MIKKNHILCEIVPGSVVFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            2736..3119
                     /locus_tag="VYN12_001674"
     CDS             2736..3119
                     /locus_tag="VYN12_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1416005.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3171..3860
                     /locus_tag="VYN12_001675"
     CDS             3171..3860
                     /locus_tag="VYN12_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1416006.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            3902..4135
                     /locus_tag="VYN12_001676"
     CDS             3902..4135
                     /locus_tag="VYN12_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416007.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4286..4897
                     /locus_tag="VYN12_001677"
     CDS             4286..4897
                     /locus_tag="VYN12_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1416008.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5058..5852
                     /locus_tag="VYN12_001678"
     CDS             5058..5852
                     /locus_tag="VYN12_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1416009.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5849..6484
                     /gene="trmB"
                     /locus_tag="VYN12_001679"
     CDS             5849..6484
                     /gene="trmB"
                     /locus_tag="VYN12_001679"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1416010.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6610..7089
                     /gene="rimP"
                     /locus_tag="VYN12_001680"
     CDS             6610..7089
                     /gene="rimP"
                     /locus_tag="VYN12_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1416011.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7133..8269
                     /gene="nusA"
                     /locus_tag="VYN12_001681"
     CDS             7133..8269
                     /gene="nusA"
                     /locus_tag="VYN12_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1416012.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8291..8584
                     /locus_tag="VYN12_001682"
     CDS             8291..8584
                     /locus_tag="VYN12_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1416013.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8577..8876
                     /locus_tag="VYN12_001683"
     CDS             8577..8876
                     /locus_tag="VYN12_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1416014.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8893..11685
                     /gene="infB"
                     /locus_tag="VYN12_001684"
     CDS             8893..11685
                     /gene="infB"
                     /locus_tag="VYN12_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1416015.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11936..12286
                     /gene="rbfA"
                     /locus_tag="VYN12_001685"
     CDS             11936..12286
                     /gene="rbfA"
                     /locus_tag="VYN12_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1416016.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3791 a         2137 c         2793 g         3717 t
ORIGIN      
        1 aatctatttg tttattgaat ttaagacttt ggtaacaaat tgaaaataaa aaggaggtat
       61 tcatcatgaa tacaaaaatg ttgtcacagt tagaggttat ggatactgaa atgcttgcga
      121 aagttgaagg ggggtatagc tccactgatt gtcaaaatgc actgattaca ggagtcacta
      181 cgggaattat aactggtgga actggagcag gtttggccac tttaggagta gctggacttg
      241 ctggtgcatt tgttggagca cacattggtg caattggggg tggattaaca tgcttaggag
      301 gtatggttgg tgataaattg ggactaagtt ggtaagactt atagtaaaat tatgaggatt
      361 ctattctgat ttattttagt tttttaaaaa aggagtattt gtcatggata caaaaatgat
      421 gtcacaattt tctgttatgg atactgaaat gcttgcttgc gttgaaggtg gcggatgcaa
      481 ttggggagat tttgccaaag caggtgttgg aggagcagct gtagttgctg ctttaggttg
      541 tgcagcgggt ggagtgaaat atgggaaaat tctaggacca tggggcgctg caataggagg
      601 aattggagga gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa
      661 gctaaatttt atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat
      721 ttatctatcc ataagtatct ctgataaaaa acaaaagact attgaattaa catcattgaa
      781 ttgttttgtc atattatttc taatctatga taaattaatt tttctcttta ttgcctatgt
      841 ttttttgata atttttatat taaacttgtt ccgtaactga aaagtgacat actatatgaa
      901 tacaaaaatg atgtcacaat tttctgttat ggataatgaa atgcttgctt gcgttgaagg
      961 tggagatatt gattggggaa gaaaaattag ttgtgcagca ggggttgcat atggcgcaat
     1021 tgatgggtgt gcaacaacgg tttgacattt ctattgggac catttgctat aggaataggt
     1081 gtaactggtg ctgcaggtgg agctatactt ggaggtgtag cctatgcagc aacatgttgg
     1141 tggtaattat ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt
     1201 atatggatga cttaattaga aaaatatttt caaaatcttc caaaaaggat acggatagta
     1261 ctctctaaaa aataaatttc tcccctgtat ttgctagctt aatttacagg ggagtttctt
     1321 taatattgtt tcgcctgtca aaatgatatg tgatagcagg atgaaaagtc tacaaacaag
     1381 ttggtatcaa tacaatataa agaggaaagt atgtttttca tgcttgcttt tttaattttt
     1441 acaattcaag aggttttgat gaccatttat gatttgagtg atccaaggtc aaaataagtg
     1501 ctatactagc agtgtaaatg ttcttgctca actaagataa atcgcacatt taggaggaaa
     1561 acttatgaag aaaaaaatac tgattatttt cgttctgtat ctgatcatgt ccatctttct
     1621 ttatccgctt agggagagta tttggtataa tctattttat accatagcct atatgattgc
     1681 ggttatgatc tatttttctt taattaaaaa gaaagaaaag aaatgaaaga ttttcttgat
     1741 taaaaagaat catattcttt gtgagattgt tcctgggtca gttgtctttg cttgtttcta
     1801 cttatctatt tctatttcgt cagttttcca atttctttta gtagttatta acttgacttc
     1861 tattttggtt actgtttatc ttactaggga aatgagatta agagagtttg aagatgatga
     1921 tttggttagt cctagaacca atcaactcat gtttatcggc ttgacaggct ttatgtctat
     1981 tatttgtttg tatagaggta tcacagcagg agaatcttat caacaactaa tcgcttatat
     2041 tggtgctatt ctttgcttga tcatcatgct tctactcatt tggggtttga agtattataa
     2101 aaagtagggg ctaatgaagt ttttgcaatt taggaggttt cgatgacaat tcaagatttg
     2161 gatgaaaaat tttaaaaaac aatgatatac taaacttgtc aaagttgcaa cgggtgctgc
     2221 tacattatgt taaaaatcgc tcttgattga taagttggat ttgttaggaa aggagtaaat
     2281 aattatggat aagaaaaaga tagtttcgac tataatatgt atagtatttc ttgtagtgtc
     2341 agtagataat ttttttagag acttaacccc gttactgttc attttaaata ttattggcct
     2401 gtcttgcttt tcagtgctaa catacattaa cataaaagag atactcttaa atataagtaa
     2461 atgatgattt ggttagtcct agaaccaatc aacttatgtt tatcggcttg gcagatttta
     2521 tgtttgtcat ttgtttgtat agaggtattt cagaaacaga attctatcaa caactaatcg
     2581 cttatatagg tgtattctct gcttgtttat cacgcttctg ctcatgtggg gcttgaagta
     2641 ttataaaaag tagctttcta tccttttctg acaggatatt tgagtagaag gctctattaa
     2701 attgttagtg aaataaatga atggaggtat ttaatatgaa atacagatta ttttttgtta
     2761 ttttcttgag tagtgtgttg gatattcttt tagggacatt tttacaaatc tctatcgtat
     2821 ctattgggtg gcttgttctt tacagtggtt tgtttgaagc aggagttttc cttcttgcta
     2881 ataaaggggt ggcggtaaaa atcaaggaag tagatattcg aaatcgcttt aaatttattt
     2941 ttggaaaaac cttatggttt caaattcttt tgctcatctt tttgataatc aaactttatc
     3001 ttggtttgga tgcgaggttg attttattct atggacatat tttcattgtc tttaatgcct
     3061 taatgtatct attatctagt agtcaggtta gccttaaaaa aaacaaactg tcttcttaat
     3121 cttacagcag tagagcctga caaggtgagg tcatagtagg gaggatttct atgaaaaagt
     3181 atcaacttct attcaaaata agtgcagttt tctcttactt atttttcgta tttggtcttt
     3241 ctcagatgac gcttattatt caaaattatt ggcaattttc ttcccagatt ggcaatttcg
     3301 tctggattca aaatttcttg agtttgctat ttagcggagt catgatttgg attctggtta
     3361 agacaggtca tggttatctc tttcacattc caagaaaaaa atggctttgg tattcgattt
     3421 tgacagtatt agtggtagtg ctccagatct cttttaacgt tcagacagct aaacatgttc
     3481 agtcaactgc tgaaggttgg gctgtattga tcggttatag tgggaccaac tttgctgagc
     3541 taggtatcta tataactttg ttctttctga ctccacttat ggaagagcta atctatagag
     3601 gattactgca acacgccttt tttaagcatt cgagatttgg ccttgatttg cttcttccgt
     3661 caattttatt tgctcttcct catttttcaa gcctgcctag tttgttagat atcttcatct
     3721 ttgcaacatc tggcatcatc tttgctagtt tgacccgcta taccaagagc atttatcctt
     3781 cctatgcggt gcatgtgatc aataatattt tcgcaacatt accatttttg ctgacttttt
     3841 tacatagggt cttggggtaa aaaaacaaaa ggcttgcttt tcagccatag aggagattat
     3901 catgtataaa cacttatttt tcctagattc caaaacttta gatcggttga caccctatat
     3961 tctagtcttg gcttctgaca ccattgcttt taatgttttt gtgctaacct ttgtatctgc
     4021 ggtggttttt aatttcctaa attccatgct agctttaatg gctatattca taggggctgg
     4081 ctatgtggtc ggattttggt tactaatact caatgaaaat caaagagcaa actaggaaac
     4141 tagccgcagg ctgtacttga gtacggcaag gcgacgttga cgtggtttga atttgatttt
     4201 cgaagagtat aaaatggttt gttttggaaa ggctagaact aaagaatgac gcgtaggaag
     4261 tctgtttggt gaggaggata gttttatgga gttttttgat aaatttcatg ccttgtgttt
     4321 tggattttta gtactaataa ttgtcattac agttccttat acgattaacc atgggggttt
     4381 ttttcaaaat gaatctgcat tgattcttgt aagtcttctt gtaacctcgc tgagtgttgc
     4441 ttatgctaga aagtttgaaa tgatttcttt tgggatgtta agcaagaaac aacttttgct
     4501 tttcattgca atctttcttc taagtgtact tgagacgctg gtttatattc atttcttcgc
     4561 tgtttcttct ggctcagggg tccaacactt ggcggaagtc agcagaggaa tttccctgtc
     4621 tttgattttg actacctcag tttttggccc catccaggag gaactcattt tcagaggact
     4681 tcttcaaggt gcggtttttg acaattcttg gttagggctt gtgctaactt cctctctctt
     4741 ttctttcatg catggacctt ctaatgtccc ttcgtttatt ttttatctac ttgggggttt
     4801 gttgctgggc tttgcttata aaaagagtca aaacctatgg gtttctactc tagtccacat
     4861 gttttacaac agttggccac tcctatatta tttataaaaa ttatgaaaag gtaagcagaa
     4921 gatggtgctt acctttttca agctataatg atacccaagc caatccagag gcttttcttt
     4981 gagaatcggg ttagagtggt tgacgaatag gccaaaaact agtagaatag taaggaaact
     5041 ttatacggag gaaagaaatg gatttgggtg ataatgagct aacactgact cccatacctg
     5101 ggaaaagtgg caaggcttat atgggtagct atcctgacgg gaagcgcatc tttgtaaaaa
     5161 tgaacacctc tccaatccta cctggtctag ctagagaaca aattgctcca caattattat
     5221 ggagtcgtcg tttggcagat gggcgtgata tgtgtgctca agaatggttg acaggcaaga
     5281 tattgacccc ctatgatatg aatcgtaagc aaatcgtcaa tattttaacc cgtcttcatc
     5341 gctcacgtcc gttgatgaca caattgagtc gtttgggcta tgccatggaa acacctgtag
     5401 atttactaca gtcttggcag gaaacggctc cagatgcttt gcgtaaaaat cattttatca
     5461 gtgaagtgat ggctgattta cgtcagacta ttccaggatt tagagaggac catgcgacca
     5521 ttgtccatgg agatgtacga catagtaatt ggattgagac agatagtggc ttgatttatt
     5581 tagtagattg ggattcggtt cgcttgaccg atcgcatgtt tgatgtggcc catatgctct
     5641 gccattatat ttcagaacat cagtggaagg aatggttgac ctactacggt tacaagtaca
     5701 atcaaacggt attaagtaaa ttgtattggt atggtcaatt gtcttatttg agtcagattt
     5761 ccaagtatta tatgaaccaa gatttagaaa atgtcaatcg ggagattcat ggtttgcgtc
     5821 atttccgaga caagtatgga aagagaagat gagagttaga aatcgtaaag gggcaacaga
     5881 attactagag gcaaatcccc agtatgtggt cctcaatccc ttggaagcca aggcaaaatg
     5941 gcgggacttg tttggcaatg ataatcccat tcatgtggaa gttggaagtg gaaagggtgc
     6001 ctttgtttca ggtatggcca agcaaaaccc tgacatcaac tatatcggga ttgatattca
     6061 aaagtctgtt ttgagctacg ctttggacaa ggtgcttgaa gttggagtgc ctaacatcaa
     6121 gctcttgtgg gtagatggtt ctgacttaac tgactatttt gaagacggtg agattgatcg
     6181 cttgtatctg aacttttcag atccatggcc gaaaaaacgc catgaaaagc gtcgtttgac
     6241 ctacaagacc ttcttggata ccttcaaacg tatcttgcct gaaaatggag aaattcattt
     6301 caagacggat aaccgtggct tgtttgagta cagtttagtg agcttttctc aatatggcat
     6361 gaaactcaat ggtgtctggt tagatttgca tgccagtgat tttgaaggta atgtcatgac
     6421 agaatacgag caaaaattct caaacaaggg gcaagttatc taccgagttg aggcagaatt
     6481 ttaagagata gcctaaaatt aggctgtaca agtgcttttg ctttacataa gttggcaaac
     6541 gtgctatact gatagtaaga atatgaaaag tgaggcgggg aaatatcttc gcctcttgct
     6601 tatgaggagg tggacgcaat cgcaacaatc gtagaattag tcagagaagt tgtagaacct
     6661 gtcatagaag ctccttttga actcgtggat atcgagtatg gaaagattgg cagtgacatg
     6721 attctcagta tttttgtaga taaacccgaa ggaattacct tgaacgacac ggcagacttg
     6781 acagaaatta tcagtcctgt cctagacacc atcaagccag atcccttccc agaacaatat
     6841 ttcctagaaa ttaccagtcc aggtttggaa cgccctttga aaaccaagga tgccgtcgct
     6901 ggagcggttg gaaaatacat ccatgtcggg ctctaccaag ccatcgataa gcaaaaggtc
     6961 tttgaaggaa ccttgttggc cttcgaagag gacgagttga ctatggaata tatggacaag
     7021 acgcgtaaga aaaccgtcca aattccatac agtttagtat caaaagcacg tttagcagtt
     7081 aaattataga aaaagaaagg atagcttttg aggattcaaa agtgaagaaa acatgagtaa
     7141 agaaatgcta gaggccttcc gcattttgga agaagacaag ggaatcaaaa aagaagatat
     7201 catcgacgca gtagtagagt cgcttcgttc cgcttatcgc agacgctatg gtcagtcaga
     7261 cagcgtagct attgacttca acgaaaaaac aggtgacttt acagtttata ctgtccgtga
     7321 agttgttgat gaagtatttg atagccgttt ggaaatcagc ttgaaagatg ctcttgccat
     7381 taattcagct tatgaacttg gagacaaaat caagtttgaa gaagcaccag ctgagtttgg
     7441 tcgtgtagca gcccagtctg ccaaacaaac catcatggaa aaaatgcgca agcaaacacg
     7501 tgccatcact tacaatactt acaaagaaca tgagcaagaa atcatgtctg gtacagtaga
     7561 acgctttgac aaccgcttta tctatgtcaa ccttggtagc atcgaagccc aattgtcaaa
     7621 acaagaccaa attcctggag aagtttttgc ttctcatgat cgtatcgaag tttatgttta
     7681 caaggttgaa gacaaccctc gtggtgtgaa tgtctttgtt agccgtagtc atccagaaat
     7741 gatcaaacgt ttaatggagc aagaaattcc agaagtttat gatggaactg ttgaaatcat
     7801 gagcgtggct cgtgaagcag gtgaccgtac gaaggttgct gttcgtagcc acaatccaaa
     7861 cgtggatgct atcggtacaa tcgttggacg tggtggtgct aatatcaaga agattactag
     7921 caaattccac ccagctcgtt acgatgctaa aaatgaccgc atggtaccaa tcgaagaaaa
     7981 tatcgatgtt atcgagtggg tagcagatcc agctgaattt atctacaatg ccatcgctcc
     8041 tgctgaggtt gaccaagtta tctttgatga aaacgacagc aaacgtgcct tggtggttgt
     8101 tccagataac aagctttctc ttgccattgg tcgtcgtgga caaaacgtgc gcttggcggc
     8161 tcacttgact ggttaccgta tcgatatcaa gtctgctagc gaatttgaag ccatggaaga
     8221 cgctgcttca gtagagttgg aagtagaaaa cgatactgta gaagaataaa agctgctaga
     8281 ggagggaaag atgaaaacaa gaaaaatccc tttgcgcaag tctgttgtgt ctaacgaagt
     8341 gattgataag cgtgatttgc tccgcattgt caagaacaag gaaggacaag tctttattga
     8401 tcctacgggc aaggccaatg gccgcggcgc ttatatcaaa ctagacaatg cagaagccct
     8461 agaggcgaaa aagaagaagg tctttaaccg cagctttagc atggaagtgg aagaaagctt
     8521 ttatgacgag ttgatcgctt atgtggatca caaagtgaaa agaagagagt tgggacttga
     8581 ataagcaaaa gataagtaat ctcttggggc ttgctcagcg agcagggcgc atcatatcgg
     8641 gtgaagaatt ggtggtcaag gccattcaag acggcaaggc caagttggtc tttctagctc
     8701 atgatgctgg acccaatctg accaagaaga ttcaagataa aagtcattat tatcaagtag
     8761 aaattgtaac cgtgttttca acactggaat taagcatagc agtcgggaaa tcgagaaagg
     8821 ttttggctgt aacagatgct ggatttacaa agaaaatgag gtctcttatg gaatagaaga
     8881 ggaggacatg atttgtctaa gaaaagattg tacgaaatcg caaaagaact tggaaaagaa
     8941 agtaaagaag ttgtagcgcg tgcaaaagag ttgggcttgg atgtgaaaag ccactcatca
     9001 agtgtggaag aagctgtcgc tgcaaaaatt gctgccagct ttaagcctgc agctgctccg
     9061 aaagtagaag caaaacctgc agcaccaaaa gtaagtgcag aaaagaaagc cgaaaaatct
     9121 gagccagcta aaccagctgt agctaaggaa gaggcaaaac cggctgagcc agttgctccg
     9181 aaaacagaaa aagtagcagt gaaaccgcaa agtcgtaatt tcaaggctga gcgtgaagcc
     9241 cgtgctaaag agcaggcaga acgacgcaag caaaataagg gcaataaccg tgaccaacaa
     9301 caaaacggaa accgtcagaa aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac
     9361 cgcgacaatc gtcgctttaa tgaccaagct aagaagcagc aaggtcagca aaaacgtaga
     9421 aatgagcgcc gtcagcaaga ggataaacgt tcaaatcaag cggctccacg tattgacttt
     9481 aaagcccgtg cagcagccct aaaagcagag caaaatgcag agtacgctcg ttcaagtgag
     9541 gaacgcttca agcagtatca ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag
     9601 gaaccagagg aaatctttga agaagcggct aagttagctg aacaagcaca gcaagttcaa
     9661 gcagtggttg aagtcgtccc tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa
     9721 caagctcgac cagacaaaaa tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa
     9781 caacaaaaga atcgaagtag tcaaaatcaa gtgagaaatc aaaagaatag taactggaat
     9841 aacaacaaaa agaacaaaaa aggcaataac aagaacaacc gtaatcagac tccaaaacct
     9901 gttacggagc gtaaattcca tgaattgcca acagaatttg aatatacaga tggtatgacc
     9961 gttgcggaaa tcgcaaaacg tatcaaacgt gaaccagctg aaattgttaa gaaacttttc
    10021 atgatgggtg tcatggccac acaaaaccaa tccttggatg gggaaacaat tgaactcctc
    10081 atggtggatt acggtatcga agccaaacaa aaggttgaag tggataatgc tgacatcgaa
    10141 cgtttctttg tcgaagatgg ttatctcaat gaagatgaat tggttgagcg tccaccagtt
    10201 gttactatca tgggacacgt tgaccacggt aaaacaaccc ttttggatac tcttcgtaac
    10261 tcacgtgttg cgacaggtga agcaggtggt attactcagc atatcggtgc ctaccaaatc
    10321 gtggaaaatg gtaagaagat taccttcctt gatacaccag gacacgcggc ctttacatca
    10381 atgcgtgcgc gtggtgcttc tgttaccgat attacgatct tggtcgtagc ggcagatgac
    10441 ggggttatgc ctcagactat tgaagccatc aaccactcaa aagcagctaa cgttccaatc
    10501 atcgtagcca ttaacaagat tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa
    10561 ttggcagagc atggtgtgat gtcaaccgct tggggtggag attctgaatt tgttgaaatc
    10621 tcagctaaat tcaaccaaaa tatcgaagaa ttgttggaaa cagtccttct tgtagctgaa
    10681 atccaagaac tcaaggcaga cccaacagtg cgtgcaatcg gtacggttat cgaagcgcgc
    10741 ttggataaag gaaaaggtgc ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt
    10801 caagatccaa tcgttgtcgg aaataccttc ggtcgtgtcc gtgctatgac caacgacctt
    10861 ggtcgtcgtg ttaaagttgc tggaccatca acaccagtct ctatcacagg tttgaacgaa
    10921 gcaccgatgg cgggtgacca ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca
    10981 ggtgaagagc gtgccaaacg tgccctcatg aaacaacgtc aagctaccca acgtgttagc
    11041 cttgaaaacc tctttgatac ccttaaagct ggggaactca aatctgttaa tgttatcatc
    11101 aaggctgatg tacaaggttc tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg
    11161 gaaggtgtca aagtgactat cgtccactca gcggtcggtg ctatcaacga atcagacgtg
    11221 acccttgccg aagcttcaaa tgcctttatc gttggtttca acgtacgccc tacaccacaa
    11281 gctcgtcaac aagcagaagc tgacgatgtg gaaatccgtc ttcacagcat tatctacaag
    11341 gttatcgaag agatggaaga agctatgaaa gggatgcttg atccagaatt tgaagaaaaa
    11401 gttattggtg aagcggttat ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt
    11461 ggatttatgg ttatcaacgg taaggttgcc cgtgactcta aagtccgtgt tatccgtgat
    11521 ggtgtcgtta tctatgatgg cgaactcgca agcttgaaac actacaaaga cgacgtgaaa
    11581 gaagtgacaa acggtcgtga aggtggattg atgatcgacg gctacaatga tattaagatg
    11641 gatgatgtga ttgaggcgta tgtcatggaa gaaatcaaga gataagattt tttgctcctt
    11701 tcttaggtgg tgagggacgc aagcaaaccg atggtttcat tgcttatttt tgagcctagg
    11761 gtctcaaaaa tcccctgtga tgggactgat aaatcagttc catcactttc accacggcga
    11821 aagaagcaga tgacttcaaa ttgaacttcg tttcaattta aactgaaaat caagaagttt
    11881 aaaatagcta ggtctgctgg cctagctttt ggttcaaagt agagaaagga atatcatggc
    11941 aaatcatttc cgtacagatc gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt
    12001 gcaaaagaaa gtccgtgatc cacgtgtcca aggtgtgacc atcacagatg ttcagatgct
    12061 gggtgacttg tctgttgcca aggtttatta caccattttg agtaaccttg cttcggataa
    12121 ccaaaaagcc caaatcgggc ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg
    12181 caatttgaaa ttgtacaaaa tcccagattt gaccttcgtc aaagacgagt ccatcgagta
    12241 tggaaacaag attgacgaga tgctacgcaa tctggataag aactaaagaa gaggggttgc
    12301 ccctcttttt tggtggagga aaataggttg aatttgaaat ggaaaaatat tcttttaaaa
    12361 tatattgaaa ctagaatagt acgcctctac ttctaaaaca ttgttagaaa tcgatttgac
    12421 tgtcctgatc gatttgtc
//
LOCUS       DAVLTG010000051        12242 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLTG010000051 DAVLTG010000000
VERSION     DAVLTG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.052"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            219..890
                     /locus_tag="VYN12_001686"
     CDS             219..890
                     /locus_tag="VYN12_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1416017.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(942..1139)
                     /locus_tag="VYN12_001687"
                     /pseudo
     CDS             complement(942..1139)
                     /locus_tag="VYN12_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1132..2040
                     /locus_tag="VYN12_001688"
     CDS             1132..2040
                     /locus_tag="VYN12_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1416018.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            2037..2498
                     /locus_tag="VYN12_001689"
     CDS             2037..2498
                     /locus_tag="VYN12_001689"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1416019.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAILKEEINGN"
     gene            2488..3375
                     /locus_tag="VYN12_001690"
     CDS             2488..3375
                     /locus_tag="VYN12_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1416020.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            3378..5261
                     /gene="cbpE"
                     /locus_tag="VYN12_001691"
                     /gene_synonym="pce"
     CDS             3378..5261
                     /gene="cbpE"
                     /locus_tag="VYN12_001691"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1416021.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            5341..6471
                     /locus_tag="VYN12_001692"
     CDS             5341..6471
                     /locus_tag="VYN12_001692"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1416022.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            6481..7743
                     /locus_tag="VYN12_001693"
     CDS             6481..7743
                     /locus_tag="VYN12_001693"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1416023.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            7747..8544
                     /gene="proC"
                     /locus_tag="VYN12_001694"
     CDS             7747..8544
                     /gene="proC"
                     /locus_tag="VYN12_001694"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1416024.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            8764..9402
                     /locus_tag="VYN12_001695"
     CDS             8764..9402
                     /locus_tag="VYN12_001695"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1416025.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            9399..10289
                     /locus_tag="VYN12_001696"
     CDS             9399..10289
                     /locus_tag="VYN12_001696"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1416026.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            10329..10646
                     /gene="yabA"
                     /locus_tag="VYN12_001697"
     CDS             10329..10646
                     /gene="yabA"
                     /locus_tag="VYN12_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1416027.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            10649..11518
                     /gene="rsmI"
                     /locus_tag="VYN12_001698"
     CDS             10649..11518
                     /gene="rsmI"
                     /locus_tag="VYN12_001698"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1416028.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKGEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            11745..>12242
                     /locus_tag="VYN12_001699"
     CDS             11745..>12242
                     /locus_tag="VYN12_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1416029.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRK"
BASE COUNT         3667 a         2102 c         2907 g         3566 t
ORIGIN      
        1 ggtggagcag attcatatgg taaaaatcct aatggtaggt acgattggga aatagaacca
       61 gtattaactc tgccggttca tggattttgt cccagaggca cctatgattt aggatatatt
      121 ggaggaggca atcatctttg caaaggaagt gctgcgagat tttaagtaaa atttattagt
      181 aatatgaaga aacaagtgga gaaagcagag aatttaatat gaaaaaacgg gctattcaaa
      241 ttttactagc attgtcctta attttttaca aatcaacttg gttttggaga gttttcaatc
      301 acctcgcaaa gccctatcta ccagcaagtc gtgaattttt tcagattctg cttttgatgg
      361 agagcggagt tcttttctta gcggtcatct atctactggt ttttgcagga aagaaaattt
      421 ttcatttcaa gtggcagctg aggtacttca tctacctttt actgggctac atcatttcat
      481 atatgtctga cttcctcttt tcgtatttca tatccctgtc ttcaaatcag atttctttga
      541 atgaaacggt agaaatgatg gggagacagg agttccctta tttcttgctc atcgtttgct
      601 tcatcgcccc tattgctgag gaattgattt atcgaggtgt gcttatgaca acctttttca
      661 aaaactcacc ttggtacgga gatgttttgc tttctgctat tattttcggt tatattcata
      721 tcaattttgc tttaactcct cttgcttttt tcatttatgc tagtggaggt cttattttag
      781 ctctattgta tcgcatgact aaaaatctct actatccaat actagttcat attctcatta
      841 atatcactgc cttctgggat gtgtggttgc tcctattttc aggaagttag cttactaaaa
      901 taatgtcgga actttccggc attttctttt ttcacaaata gtcaacggtt ttcttttcga
      961 tattgtagtg gtgtgtatcc agttattttt ttgaattgat tttgaaaata aggttggctt
     1021 gagaaaggca gatagtgaag atagttaaga agaagaggat gttctttttt cctttttgga
     1081 aaacttctaa aatatggtat aatgaaaaga taaagaagtt aggggtagaa gatgaacatt
     1141 caacaattac gctatgttgt ggccattgcc aatagtggta ctttccgtga agctgctgaa
     1201 aagatgtatg ttagtcagcc gagtctgtct atttctgttc gtgatttgga aaaagagttg
     1261 ggttttaaga ttttccgtcg gaccagctca gggactttct tgacccgtcg tgggatggaa
     1321 ttttatgaaa aagcgcaaga attggttaaa ggatttgata tttttcaaaa tcagtatgcc
     1381 aatcctgaag aagaaaaaga tgaattttct gttgctagcc agcactatga cttcttgcca
     1441 ccaactatta cggccttttc agagcgctat cctgactata agaacttccg tatttttgaa
     1501 tcaactactg ttcaaatatt agatgaagtg gcgcaagggc atagtgagat tgggattatc
     1561 tacctcaaca atcaaaataa aaaggggatt atgcaacggg ttgaaaaatt aggtctggag
     1621 gtcatcgaat tgattccttt ccatacccat atttatctcc gtgagggtca tcctttagcc
     1681 cagaaagagg aattagtcat ggaggattta gcggatttac caacggttcg tttcactcaa
     1741 gagaaagacg agtaccttta ttattcagag aactttgtcg ataccagcgc tagctcacag
     1801 atgtttaatg tgacagaccg tgccaccttg aatggtattt tggagcggac ggacgcctat
     1861 gcgacaggtt ctggattttt agatagtgac agtgttaatg gcattacagt tattcgtctc
     1921 aaggataacc tagataaccg catggtctat gttaaacgtg aagaagtgga gcttagtcaa
     1981 gctgggactc tcttcgtaga agtcatgcaa gaatattttg atcaaaagag gaaatcatga
     2041 aaaaaagagc aatagtggca gtcattgtac tgcttttaat tgggctggat cagttggtca
     2101 aatcctatat cgtccagcag attccactgg gtgaagtgcg ctcctggatt cccaatttcg
     2161 ttagcttgac ctacctgcaa aatcgaggtg cagccttttc tatcttacaa gatcagcagc
     2221 tgttattcgc tgtcattact ctggttgtcg tgataggtgc catttggtat ttacataaac
     2281 acatggagga ctcattctgg atggtcttgg gtttgactct aataatcgcg ggtggtcttg
     2341 gaaactttat tgacagggtc agtcagggct ttgttgtgga tatgttccac cttgacttta
     2401 tcaactttgc aattttcaat gtggcagata gctatctgac ggttggagtg attattttat
     2461 tgattgcaat actaaaagag gaaataaatg gaaattaaaa ttgaaactgg tggtctgcgt
     2521 ttggataagg ctttgtcaga tttgtcagaa ttatcacgta gtctcgcgaa tgaacaaatt
     2581 aaatcaggcc aggtcttggt caatggtcaa gtcaagaaag ctaaatacac agtccaagag
     2641 ggtgatgtcg tcacttacca tgtgccagaa ccagaggtat tagagtatgt ggctgaggat
     2701 cttccgctag aaatagtcta ccaagatgag gatgtggctg tcgttaacaa acctcaggga
     2761 atggttgtgc acccgagtgc tggtcatacc agtggaaccc tagtaaatgc cctcatgtat
     2821 catattaagg acttgtcggg tatcaatggg gttctgcgtc cagggattgt tcaccgtatt
     2881 gataaggata cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca tctagtactt
     2941 gcccaagaac tcaaagataa aaagtctctc cgcaaatatt gggcgattgt tcatggaaat
     3001 ctgcctaatg atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa agaccgtaag
     3061 aaacaggctg taactgctaa agggaagcct gcagtgacgc gttttcacgt cttggaacgc
     3121 tttggcgatt atagcttagt agagttgcaa ctggagacag ggcgcactca tcaaatccgt
     3181 gtccacatgg cttatatcgg ccattcagtc gctggtgatg aggtctatgg tcctcgcaag
     3241 actttgaaag gacatggaca atttcttcat gccaagactt taggttttac tcatccgaga
     3301 acaggtaaga ccttggaatt taaagcagat atcccagaga tttttaagga aaccttggag
     3361 agattgagaa agtaagaatg aaaaagaaat taactagttt agcacttgta ggcgcttttt
     3421 taggtttgtc atggtatggg aatgttcagg ctcaagaaag ttcaggaaat aaaatccact
     3481 ttatcaatgt tcaagaaggt ggcagtgatg cgattattct tgaaagcaat ggacattttg
     3541 ccatggtgga tacaggagaa gattatgatt tcccagatgg aagtgattct cgctatccat
     3601 ggagagaagg aattgaaacg tcttataagc atgttctaac agaccgtgtc tttcgtcgtt
     3661 tgaaggaatt gggtgtccaa aaacttgatt ttattttggt gacccatacc cacagtgatc
     3721 atattggaaa tgttgatgaa ttactgtcta cctatccagt tgaccgagtc tatcttaaga
     3781 aatatagtga tagtcgtatt actaattctg aacgtctatg ggataatctg tatggctatg
     3841 ataaggtttt acagactgct gcagaaaaag gtgtttcagt tattcaaaat atcacacaag
     3901 gggatgctca ttttcagttt ggggacatgg atattcagct ctataattat gaaaatgaaa
     3961 ctgattcatc gggtgaatta aagaaaattt gggatgacaa ttccaattcc ttgattagcg
     4021 tggtgaaagt caatggcaag aaaatttacc ttgggggcga tttagataat gttcatggag
     4081 cagaagacaa gtatggtcct ctcattggaa aagttgattt gatgaagttt aatcatcacc
     4141 atgataccaa caaatcaaat accaaggatt tcattaaaaa tttgagtccg agtttgattg
     4201 ttcaaacttc ggatagtcta ccttggaaaa atggtgttga tagtgagtat gttaattggc
     4261 tcaaagaacg aggaattgag agaatcaatg cagccagcaa agactatgat gcaacagttt
     4321 ttgatattcg acaagacggt ttagtaaaca tttcaacttc ctacaagccg attccaagtt
     4381 ttcaagctgg ttggcataag agttcatatg gaaactggtg gtatcaagcg cctgattcta
     4441 caggagaata tgctgtcggt tggaatgaaa ttaagggtga atggtattac tttaaccaaa
     4501 cgggtatctt attacagaat caatggaaaa aatggaacaa tcgttggttc tatttgacag
     4561 actctggtgt tgctgctaaa aattggaaga aaatcgctgg aatctggtat tattttaaca
     4621 aagaaaacca gatggaaatt ggttggattc aagataaaga gcagtggtat tatttggatg
     4681 ttgatggctc tatgaagaca ggttggcttc aatataaggg gcaatggtat tactttgctc
     4741 catcagggga aatgaaaacg ggctgggtaa aagataaaga agcctggtac tatatggatt
     4801 ctactggtat catgaagaca ggtgagatag aagttgctgg acatcattac tatctagaag
     4861 aatcaggagc tatgaagcaa ggctggctta aaaaggcaaa tgattggtat ttctacaaga
     4921 cagatggttc acgagctata ggttggatta aagacaagga taaatggtac ttcttgaaag
     4981 aaaatggtca attacttgtg aatggtaaga caccagaagg ctatactgtg gattcaagtg
     5041 gtgcctggtt agtggatgtt ccgatcgaga aatctgctac aattaaaact acaagtcatt
     5101 cagaaataaa agaatccaaa gaagtagtga aaaaggatct tgaaaataaa gaaacgagtc
     5161 aacatgaaag tgttacaaat tcttcaacta gtcaagattt gacatcctca acttcacaaa
     5221 gctctgaaac gagtgtaaac aaatcggaat cagaacagta gtagaaaaga aggttttagg
     5281 gccttctttt tcctatcaac tcttttctat ttcctgttat tcatgttata atggataaat
     5341 atgaataatc ggagtgagac tatgaaatac aaacggattg tctttaaggt gggtacttct
     5401 tctctgacaa atgaggatgg aagtttatca cgtagtaagg taaaggatat tacccagcag
     5461 ttggctatgc tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg tgccattgcg
     5521 gctggttttg gagccttagg atttaaaaag cgtccgacta aaattgctga taaacaggct
     5581 tcagcagcgg tagggcaggg acttttgttg gaagaatata cgaccaatct tctcttgcgt
     5641 caaatcgttt ctgcacaaat cttgctgacc caagatgact ttgtggataa gcgtcgttat
     5701 aaaaatgccc atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc tatcatcaat
     5761 gagaatgata gtgtcgttat tgatgagctc aaggttgggg acaatgacac tctaagtgct
     5821 caagtagcgg cgatggtcca agcagacctt ttagttttct tgacagatgt ggacggtctc
     5881 tatactggaa atcctaattc agatccaaga gccaaacgct tggagagaat cgagaccatc
     5941 aatcgtgaga ttattgatat ggctggtgga gctggttcgt caaacggaac tgggggtatg
     6001 ttaaccaaaa tcaaggctgc aactatcgcg acggaatcag gagttcctgt ttatatctgc
     6061 tcatccttga aatcagattc catgattgag gcggcagagg agaccgagga tggttcttac
     6121 tttgttgctc aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt ctatgctcag
     6181 agtcaaggtt ctatttgggt tgataaaggg gctgcggaag ctctctctca acatggaaag
     6241 agtcttctct tatctggtat cgttgaagca gaaggagtct tttcttacgg tgatatcgtg
     6301 acagtatttg ataaggaaag tggaaaatca cttggaaaag gacgcgtgca atttggagca
     6361 tctgctttgg aggatatgtt gcgttctcaa aaagccaagg gtgtcttgat ttaccgtgac
     6421 gactggattt ccattactcc tgaaatccaa ctacttttta cagaatttta gaggtaaact
     6481 atggtgagta gacaagaaca atttgaacag gtacaggctg ttaaaaaatc gattaacaca
     6541 gctagtgaag aagtgaaaaa ccaagccttg ctagccatgg ctgatcactt agtggctgct
     6601 actgaggaaa ttttagcggc taatgccctc gatatggcag cggctaaggg gaaaatctca
     6661 gatgtgatgt tggatcgtct ttatttggat gcagatcgta tagaagcgat ggcaagagga
     6721 attcgtgaag tggttgcctt accagatcca atcggtgaag ttttagaaac aagtcagctt
     6781 gaaaatggtt tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg tattatctat
     6841 gaaagccgtc caaatgtgac gtctgatgcg gctgctttga ctcttaagag tggaaatgcg
     6901 gttgttcttc gtagtggtaa ggatgcctat caaacaaccc atgccattgt cacagccttg
     6961 aagaagggct tggagacgac tactattcat ccaaatgtga ttcaactggt ggaggatact
     7021 agccgtgaaa gtagttatgc tatgatgaag gccaagggct atctagacct tctcattcct
     7081 cgtggaggag ctggcttgat caatgcagtg gttgagaatg cgattgtacc tgttatcgag
     7141 acagggactg ggattgtcca tgtctatgtg gataaggatg cagacgaaga caaggcgctg
     7201 tctatcatca acaatgctaa aaccagtcgt ccttctgttt gtaatgccat ggaggttctg
     7261 ctggttcatg aaaacaaggc agcaagcatc cttcctcgct tggatcaaat gctggttgca
     7321 gatcgaaaag aagctgggtt ggaaccaatt caattccgcc tagatagcaa agcaagccag
     7381 tttgtttcag gtcaagctgc tcaagcacaa gactttgata ccgagttttt agactatatt
     7441 ctagctgtta aggttgtgag cagtttagaa gaagcggttg cgcatattga atcccacagt
     7501 acccatcatt cggatgctat tgtgacggaa aatgctgaag ctgcagcata ctttacagat
     7561 caagtggact ctgcagcggt gtatgttaat gcctcaactc gtttcacaga tggaggacaa
     7621 tttggtcttg gttgtgaaat ggggatttct actcagaaat tgcacgcgcg tggtccaatg
     7681 ggcttgaaag agttgaccag ctacaagtat gtggttgctg gtgatgggca gataagggag
     7741 taagagatga agattggatt tatcggtttg gggaatatgg gtgctagctt ggcaaaatct
     7801 gtcttgcaga ctaggacgtc agatgagatt ctccttgcca atcgtagtca agctaaggta
     7861 gatgctttca ttgcagactt tggtggtcag gcttccagca atgaagaaat gtttgcagaa
     7921 gcagatgtga tttttctagg agttaagcct gctcagtttt ctgaactgct ttctcaatat
     7981 cagaccatcc ttgaaaaaag agaaagtctt cttttgattt cgatggcagc tggattgacc
     8041 ttagaaaaac tagcaagtct tatcccaagc caacaccgaa ttattcgtat gatgcctaat
     8101 acccctgctt ctatcgggca aggagtgatt agttatgcct tgtctcctaa ttgcagggct
     8161 gaggacagtg agatcttttg tcagctttta gccaaggctg gtctcttggt tgaattagga
     8221 gaaagcttaa tcaatgcagc gacaggtctt gcaggttgtg gaccagcctt tgtctatctc
     8281 tttattgagg ccttggcaga tgcaggtgtt cagacgggat taccacgaga aacagccttg
     8341 aaaatggcag cccaaactgt ggtaggagct gggcaattgg tcctagaaag ccagcaacat
     8401 cctggagttt tgaaagatca agtttgtagt ccaggcggtt cgactattgc tggcgtagca
     8461 agcctagaag cgcatgcttt tcgaggcaca gtcatggagg cagttcatca agcctataaa
     8521 cgaacacaag aactaggtaa ataagaggta gttttatctg cctcttttat ggtggttgat
     8581 actcttcgaa aatcaaattc aaactgcgtc agcttcacct tgccgtactc aagtacagcc
     8641 tgcggctagc ttcctagttt gctctttgat tttcattgag tatgaaatga gaagacaaaa
     8701 agattgtcac aaacccctat ttttttgata gaatagaagt agtaaaaaag aaatgagtta
     8761 gacatgtcaa aaggattttt agtctctctt gagggaccag agggagcagg caagaccagt
     8821 gttttagagg ctctgctacc aattttaaag gaaaaaggag tagaggtgtt gacgacccgt
     8881 gaacctggcg gagtcttgat tggggagaag attcgggaag tgattttgga tccaagtcat
     8941 actcagatgg atgctaaaac agagctactt ctctatattg ccagtcgcag acagcatttg
     9001 gtggaaaaag ttcttccagc ccttgaagct ggcaagttgg tcatcatgga tcgttttatc
     9061 gatagttctg ttgcctatca gggatttggt cgtggcttag atattgaagc cattgactgg
     9121 ctcaatcagt ttgcgacaga tggcctcaaa cccgatttga cactctattt tgacatcgag
     9181 gtggaagaag ggctggctcg tattgctgcg aatagtgacc gcgaggttaa tcgtttggat
     9241 ttggaagggt tggacttgca taaaaaagtt cgtcaaggct acctttctct tctggataaa
     9301 gagggaaatc gcattgtcaa gattgatgct agtctccctt tggagcaagt tgtggaaact
     9361 accaaggctg tcttgtttga cggaatgggc ttggccaaat gaaacaagat caactaaagg
     9421 cttggcaacc agctcagttt gaccgttttg tccgtatctt agaacaagac cagctcaatc
     9481 acgcctatct cttttcaggt ttctttggaa gcttggaaat ggcgcaattt ttagctaaga
     9541 gcctcttttg tacggataaa gttggcgtct taccatgtga gaaatgccga agttgcaagc
     9601 tgattgaaca ggaagagttt ccagatgtca ccttgattaa gccagtcaat caggtcatca
     9661 agacagaacg cattcgggaa ttggtgggac agttttctca agcagggatt gaaagccagc
     9721 aacaggtctt tattatcgag caagcggata aaatgcatcc caacgcagcc aattctctgc
     9781 tcaaggtcat cgaagaaccc cagagtgaag tttatatttt cttcttgact agcgatgagg
     9841 aaaagatgtt accgacaatc cgaagtcgga ctcagatctt ccactttaaa aagcaagaag
     9901 aaaaacttat cttactctta gaacaaatgg gacttgttaa gaaaaaagcg actcttttag
     9961 ctaagtttag tcaatcgcga gctgaagcag aaaagttggc taatcaggca agtttttgga
    10021 ccttggtcga tgaaagtgaa cgcctgctga cttggttagt agctaagaaa aaagaaagtt
    10081 atctacaggt tgccaaatta gccaacttgg cagatgataa ggaaaaacag gatcaggttt
    10141 tacggattct tgaagttctc tgtgggcagg acctcttgca ggtaagagta agagtgattc
    10201 tacaagattt actagaagct agaaaaatgt ggcaagctaa tgtcagcttt caaaatgcca
    10261 tggaatatct ggtcttgaaa gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg
    10321 gctgttttat ggacaaaaaa gaattatttg acgcgctgga tgatttttcc caacaattat
    10381 tggtaacctt agccgatgtg gaagccatca agaaaaatct caagagcttg gtagaagaaa
    10441 atacagctct tcgcttggaa aatagtaagt tgcgagaacg cttgggtgag gtggaagcag
    10501 acgctcccgt caaggccaag catgttcgcg aaagtgtccg tcgtatttac cgtgatggat
    10561 ttcacgtatg taatgatttt tatggacaac gtcgagagca ggacgaagaa tgtatgttct
    10621 gtgatgagtt gttatacagg gagtaagcat gcaaattcaa aaaagtttta aggggcagtc
    10681 tccctatggc aagctgtatc tagtggcaac gccgattggc aatctagatg atatgacttt
    10741 tcgtgctatc cagaccttga aagaagtgga ctggattgct gctgaggata cgcgcaatac
    10801 agggcttttg ctcaagcatt ttgacatttc caccaagcag atcagttttc atgagcacaa
    10861 tgccaaggaa aaaattcctg atttgattgg tttcttgaaa gcagggcaaa gtattgctca
    10921 ggtctctgat gccggtttgc ctagcatttc agaccctggt catgatttgg ttaaggcagc
    10981 tattgaggaa gaaattgcag ttgttacagt tccaggtgcc tctgcaggaa tttccgcctt
    11041 gattgccagt ggtttagcgc cgcagccaca tatcttttac ggctttttac cgagaaaatc
    11101 aggccagcaa aagcaatttt tcgactcgaa aaaagactat cctgaaactc agatttttta
    11161 tgaatcgccc catcgtgtgg cagatacatt ggaaaatatg ctagaagtct acggtgaccg
    11221 ctccgttgtc ttggtcaggg aattgaccaa aatctatgaa gaataccaaa gaggtacaat
    11281 ttctgaattg ctggaaagca ttgctgaaac gtctctcaag ggtgaatgtc ttctgattgt
    11341 tgaaggtgcc agtcaggatg tggaagaaaa aggcgaggaa gacttgttct tagaaatcca
    11401 agctcgtatt cagcaaggta tgaagaaaaa tcaagctatt aaggaagtag ctaagattta
    11461 ccagtggaat aagagtcaac tctacgctgc ctaccacgac tgggaagaaa aacaataaag
    11521 ggagacagga tgtaataatt ctgtctgttt ctgtttaact taattagtga tgataatata
    11581 aagatgtatc acttggtata gaagctttgg tattaagttt tttattaagc ccatacggaa
    11641 taccgatggt tggagcagca gttatagcgt tcttagaagg tataaataga aaaataaggt
    11701 cattttaaat caaaggattg ataaatcaga aagaaggtga ttttttgcga acatacgaaa
    11761 ataaagaaga actaaaagct gagatagaga aaacatttga gaaatatatt ttagaatttg
    11821 ataatattcc agaaaattta aaagataaga gagctgatga agttgacaga actccagcag
    11881 aaaaccttgc ttatcaggtt ggttggacca acttggttct taaatgggaa gaagatgaaa
    11941 gaaaggggct tcaagtaaaa acaccatcgg ataaatttaa atggaatcaa cttggtgaat
    12001 tatatcagtg gttcacagat acctacgctc atttatctct gcaagagttg aaagcaaaat
    12061 taaatgaaaa tattcattct atctctgcaa tgattgattc gttgagtgag gaagaattat
    12121 ttgaaccgca tatgagaaag tgggctgatg aagcgactaa aacagcgact tgggaagtgt
    12181 ataagtttat tcatgtaaat acggttgcac cttttggaac tttcagaact aaaatcagaa
    12241 aa
//
LOCUS       DAVLTG010000052        11530 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLTG010000052 DAVLTG010000000
VERSION     DAVLTG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.053"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            110..763
                     /locus_tag="VYN12_001700"
     CDS             110..763
                     /locus_tag="VYN12_001700"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1416030.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            773..1237
                     /locus_tag="VYN12_001701"
     CDS             773..1237
                     /locus_tag="VYN12_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1416031.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1250..2518
                     /locus_tag="VYN12_001702"
     CDS             1250..2518
                     /locus_tag="VYN12_001702"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1416032.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     NATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2532..2792
                     /locus_tag="VYN12_001703"
     CDS             2532..2792
                     /locus_tag="VYN12_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416033.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2803..4164
                     /gene="pdrM"
                     /locus_tag="VYN12_001704"
     CDS             2803..4164
                     /gene="pdrM"
                     /locus_tag="VYN12_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1416034.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4318..5286
                     /locus_tag="VYN12_001705"
     CDS             4318..5286
                     /locus_tag="VYN12_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1416035.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5302..6294
                     /locus_tag="VYN12_001706"
     CDS             5302..6294
                     /locus_tag="VYN12_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1416036.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6512..7555
                     /locus_tag="VYN12_001707"
     CDS             6512..7555
                     /locus_tag="VYN12_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1416037.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7619..9304
                     /gene="lpdA"
                     /locus_tag="VYN12_001708"
     CDS             7619..9304
                     /gene="lpdA"
                     /locus_tag="VYN12_001708"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1416038.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9368..10357
                     /locus_tag="VYN12_001709"
     CDS             9368..10357
                     /locus_tag="VYN12_001709"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1416039.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYN12_001710"
     CDS             complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYN12_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1416040.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAKNIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         3391 a         2174 c         2612 g         3353 t
ORIGIN      
        1 tcaaatcgta tatatagtcg atttattaaa tctttagata aactgtaaaa agtggtttcc
       61 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcagcta tggaacactc
      121 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
      181 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
      241 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
      301 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
      361 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
      421 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
      481 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
      541 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
      601 taagaagaag gccttagtta ccaatcctca tcacttgatt attgaatcag cccatccaag
      661 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt
      721 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
      781 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
      841 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
      901 agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa
      961 gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac
     1021 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     1081 agaatgggtt ccctatgacg aggttttgag caagccgact tgggaaggtg accacacctt
     1141 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     1201 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     1261 caaaaatggt cgtgtaatgg atcctaagtc tggtttggat caagtttgtg atgtcttagt
     1321 tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag cagaaacgat
     1381 taatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc atttccgtga
     1441 acctggtcaa acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg
     1501 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     1561 gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     1621 tactaaaaac tttaatggta aaaacttgac tgactttaag gcgctcttag aagctggtgc
     1681 ggttggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     1741 ggaggaagcc aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa
     1801 cggtgttctt ggctttaatg aaaatattgc tagagaacat tttcatatct gcggtgctac
     1861 tggggtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     1921 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     1981 ggggttaggt gcagaagtca cagcagaagt agcgccacag catttctcta agacagaagc
     2041 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     2101 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     2161 cgcgcctcat catgtagatg aaaaaaatgt tgaggatatt accaaagcgc catctggtat
     2221 gactggctta gaaacatccc tgtctctcag cttgacctat ttagtagaag ctggtgagtt
     2281 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttga
     2341 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     2401 ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     2461 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     2521 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     2581 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     2641 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     2701 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     2761 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     2821 ttacgagaga agttagtatt atttttaaaa attttcttcc caatactgat ctaccaattt
     2881 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     2941 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     3001 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggaaa aaaggaagaa
     3061 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     3121 gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga agcagcagta
     3181 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     3241 tttagcgtca ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc
     3301 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     3361 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     3421 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     3481 gagaaacgaa ttccacttaa tatggataaa attaaggaag gagttcgttt aggtctgcct
     3541 attgggggaa ctgtcttcgc ggaagtggct gtcttttcag tggttggctt gattatggct
     3601 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     3661 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     3721 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgccctcatt
     3781 tttgcggcct tcaccttaac cttcctttac atttttaggg gaaatgtggc cagtctttat
     3841 ggtaacgacc caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc
     3901 cagttagcag atacctttgc ggcgccgctt cagggaattt tgcgggggta taaggataca
     3961 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg
     4021 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     4081 ttgattgtga gcggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     4141 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgac aagaaaatcc
     4201 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     4261 gtatttgcca aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     4321 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     4381 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     4441 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     4501 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga
     4561 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     4621 catatcgctg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     4681 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtt
     4741 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     4801 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     4861 gatatcaaga aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt
     4921 cctggaatgt tcatcgaaga cggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     4981 gctgtagacc atgttcgcag tggcaatggt tcagtcttga ttgaaagtgt aacttatcgc
     5041 tggctcggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     5101 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     5161 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     5221 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     5281 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     5341 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagatgtc
     5401 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa
     5461 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagcagcagc aggagcagcc
     5521 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     5581 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     5641 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     5701 tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct
     5761 gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt
     5821 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     5881 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga
     5941 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaaga aatttcagtt
     6001 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     6061 aagaagactg gtaaggttat tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     6121 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaatacgc
     6181 cgttgttcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     6241 ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga ctagagttac
     6301 ataatataag ttatgtaact aaaataaagc tgacgagaaa ctttgtatct tttaggtgca
     6361 gagctcttcg tcattaatat cttatattcg agcacgggct aaaagctcgg aaaaaagata
     6421 aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc
     6481 cctttgtatc ataaatagaa ttggagaggt catggctgat gacaagctaa gagcgactcc
     6541 tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg
     6601 tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg
     6661 catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca
     6721 aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa
     6781 tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga
     6841 taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat
     6901 tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt
     6961 tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac
     7021 tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa
     7081 acacccatac atcaacgctt cattgacaga agatggcaag actattatca ctcacaacta
     7141 tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa
     7201 tgctgagaag atgagtcttt cagaactggt ggtagccttt aaggatgtta ttggccgtac
     7261 cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt
     7321 gggaatgttt ggtgttcagt cctttggtcc gattattaac caacccaact cagctatcct
     7381 tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc
     7441 aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa
     7501 gtttatgaag gacttgaaag agttgattga aacgccaatc tcaatgttaa tttaagagca
     7561 agagtattca tttttaagat atagataaag gaaggaagac atggccttag aaataattat
     7621 gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg
     7681 agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga
     7741 attggaagcc gaagaagatg ggtacttgat tgccattctc aaaggagatg gtgaaactgt
     7801 ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg
     7861 agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa
     7921 gagcgatgat gcttttgata tcgttgtgat tggtggaggt cctgctggtt atgttgcagc
     7981 cattaaagct gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg
     8041 aacctgctta aaccgtggat gtattccaac caagacctac cttcatagcg ctgaaattat
     8101 tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt
     8161 tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt
     8221 tgcaggactt cttcgtagct acggagttgc tgttcataaa ggaattggta caatcactaa
     8281 agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc
     8341 tggtggttca aaagtcagca agatcaacgt ccctggtatg gaatctccac ttgtcatgac
     8401 tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg
     8461 agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat
     8521 cgaaatgatg gaccgtatag ttccagctat ggatgtggaa gtttctaaga accttcgctt
     8581 gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga
     8641 ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc
     8701 tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt
     8761 ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc
     8821 accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt
     8881 ttccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc
     8941 agccatctac actcttcctg aagtagcagc agtaggtttg acagaagaac aagcccgtga
     9001 gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc
     9061 tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg
     9121 tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga
     9181 aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga
     9241 agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa
     9301 ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag
     9361 ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga
     9421 agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa
     9481 gccatctatc attgttggtc gtcaccagaa cactattgaa gaaatcaacc gtgattatgt
     9541 tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga
     9601 tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt
     9661 caagagcttc tcaactccgg ttatcaatac cttggctcaa ctcggggtta aagctgagtt
     9721 cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta
     9781 tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct
     9841 cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg
     9901 tgcccgtgta accaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg
     9961 tgatttactc ttggaataca tgaaaaaaga gtacccagag atgactgaat acgtcttttc
    10021 agaagaagaa ttggccgaaa tcaatcgcat caaggatact aagtttggaa cttgggactg
    10081 gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa
    10141 ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga
    10201 cttctttggt attgaagacg ttgctgcagt agaagatgtc cttcgtgggg tgaaatacga
    10261 acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat
    10321 tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta
    10381 accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat
    10441 ccagagcatt cttttgttca tcactaacaa tatgggtata gaggtcagtg acttgtgtgc
    10501 tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag
    10561 ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    10621 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    10681 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    10741 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt
    10801 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    10861 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    10921 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    10981 tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg atatttttag
    11041 ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat
    11101 agaaataagg ttccccctga tcgttttcaa cctcttcggt tagatacttg taaagactag
    11161 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    11221 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    11281 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    11341 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    11401 tgtagggcac agccagctta gattggtagt attccagaac ataccagggc atgagttgtt
    11461 ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc cataagtaag
    11521 tatactagta
//
LOCUS       DAVLTG010000053        11499 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLTG010000053 DAVLTG010000000
VERSION     DAVLTG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.054"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(131..1762)
                     /locus_tag="VYN12_001711"
     CDS             complement(131..1762)
                     /locus_tag="VYN12_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1416041.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2055..7034
                     /locus_tag="VYN12_001712"
     CDS             2055..7034
                     /locus_tag="VYN12_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1416042.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTVQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7124..8320
                     /locus_tag="VYN12_001713"
     CDS             7124..8320
                     /locus_tag="VYN12_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1416043.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8456..8983
                     /locus_tag="VYN12_001714"
     CDS             8456..8983
                     /locus_tag="VYN12_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1416044.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9060..9416
                     /gene="glnR"
                     /locus_tag="VYN12_001715"
     CDS             9060..9416
                     /gene="glnR"
                     /locus_tag="VYN12_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1416045.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9453..10799
                     /gene="glnA"
                     /locus_tag="VYN12_001716"
     CDS             9453..10799
                     /gene="glnA"
                     /locus_tag="VYN12_001716"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1416046.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10895..11014)
                     /locus_tag="VYN12_001717"
     CDS             complement(10895..11014)
                     /locus_tag="VYN12_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1416047.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11272..11409
                     /locus_tag="VYN12_001718"
     CDS             11272..11409
                     /locus_tag="VYN12_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416048.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEVLNIRLEVK
                     N"
BASE COUNT         3667 a         2116 c         2497 g         3219 t
ORIGIN      
        1 aaatagaggt gtactattct agtttcaata tattatatat ctgcagaata ctctttcagt
       61 ttcattcagc ctagtcttgc ttaggaaaaa gtaagaagcc atccaattat gatggatagc
      121 ttcttggtta ttagatttgt tctgcaaaaa ccttttcagc aaggttcata gcgtggtctg
      181 atacacgagt gtagtgtgag atgatgtcga taaagttgac tccagcttgt gttgaacatt
      241 cgcctttgtt gaggcgtttg atgtgggttt ttctgagaac acgttctatc ttattgattg
      301 cttcatgacg ttctacaaga ctgcgtgctt tttcaatatc attgttttcc acactatcca
      361 gagcatcttt gataaagtca ctagtttggc ggtaaacttc ctctaattct ttcaaggcgg
      421 catcagaaaa ttcaacattt ttccgttgaa gatagtcagt cagattgagt agagcctccg
      481 tgtggtctcc aatccgttcc aaatcacggg aggaatcaag gatattggta agcacttcac
      541 tttctttttg gctgagagct tcgcttgaaa gggcaatgag ataacgtgtt aattgctcat
      601 cgatggtgtt aattgcttct tcggttttat gccctttttc agcaactttt tcatccaagt
      661 caatgatgta cttataggaa aggtcaaagg ctttagcagc gtagtttcct aagtgcaaga
      721 gctctttctt agcatttcct agagcgatag atggggcctg tttgatgaaa tgttcatcaa
      781 gatataaggg ttcgtatttg acaacctcgt cctctccagg aataatcttg gttacaaagt
      841 aagccagagc tccgataaat ggaaattgga caatggtgtt ggtaatatta aaggttccgt
      901 gagcaaaggc gatggtcatt tccggtgcta gatttagcgt agcttcaaac caatgaatca
      961 ggacagtaaa aggaactaga aaaataacgc agacgactgt tccgataatg ttgaaggcaa
     1021 catgagctcc tgctacccgt ttagctgcaa tattagcccc taaagaggca atgatggctg
     1081 taatggttgt cccgatattg tcaccaaata gaactggcaa agctccctgt aggtcaatta
     1141 gattgccggc gtagaggttt tgtaaaatcc caatggtagc cgaagaagct tgaattagca
     1201 aggtcaagcc agtaccgaca aagacaccca aaacaggatt cttacttagc tcaatcatat
     1261 agtccttaaa gacctgtaaa tccttgagtg gagccattgc gccgctcatg agattgaggg
     1321 caaaaaagat accaccgata ccaaagagga tgcgtccgat attattgact gtccgatttt
     1381 ttgtaaaaaa gagacagacg gcaccgataa agagcatagg tagggcatag ttacctaatt
     1441 taaaaccgat gagaaaggat gtgacagttg tcccaatatt agcacccatg acaatcccga
     1501 tagcctgacg taaggttaag agaccggcac tgaccaggcc gactgtgata actgttacac
     1561 cagaactaga ctgaattaga gcagtcatcc caataccaac cagaactcca aagaaaggat
     1621 tactagtata tttgtcaatg taaaaacgaa ggcgatctcc agcagcttgt tgcaaaccgt
     1681 ctcccatggt cttgatgcta tataagaata gccccagacc acctaaaaag tgaaataaaa
     1741 tttcctgcca attaatggac atttcttttt cctccgaaaa ataatcgcgg aatatctcct
     1801 attctatttt aaaggataaa agtaaatcta acaagtgtta atgtcaagtt tgtaaaagaa
     1861 aattataatt gataagtgta ttatttttaa gagtttttaa ccttatttta gatttgtgca
     1921 aacagttatt gttttttgtc taaaaatgtt ttaggataaa aatgtgatta tcatggttct
     1981 agagtttgat aaaaaactac agaatataaa gcgctttctt gaaaacaaca aaatcaatct
     2041 tttaggagga gaaaatgaag aatccatttt ttgaaagacg ttgtcgttac agtattcgta
     2101 agttatcagt aggagcctgc tcgctgatga ttggtgctgt tttatttgct ggtccagcct
     2161 tggctgaaga aactgcagtt cctgaaaata gcggagctaa tacagagctt gtttcaggag
     2221 agagtgagca ttcgaccaat gaagctgata agcagaatga aggggaacat gctagagaaa
     2281 acaagctaga aaaggcagaa ggagtagcga tagcatctga aactgcttcg ccagcaagca
     2341 atgaagctgc aactactgaa actgcagaag cagctagcgc agctaaacca gaggaaaaag
     2401 caagtgaggt ggttgcagaa acaccatctg cagaagcaaa acctaagtct gacaaggaaa
     2461 cagaagcaaa gcccgaagca actaaccaag gggatgagtc taaaccagca gcagaagcta
     2521 ataagactga aaaagaagtc cagccagatg tccctaaaaa tacagaaaaa acattaaaac
     2581 caaaggaaat caaatttaat tcttgggaag aattgttaaa atgggaacca ggtgctcgtg
     2641 aagatgatgc tattaaccgt ggatctgttg tcctcgcttc acgtcggaca ggtcatttag
     2701 tcaatgaaaa agctagcaag gaagcaaaag ttcaagcctt atcaaacacc aattctaaag
     2761 ccaaagacca tgcttctgtt ggtggagaag agttcaaggc ctatgctttt gactattggc
     2821 aatatctaga ttcaatggtc ttctgggaag gtctcgtacc aactcctgac gttattgatg
     2881 caggtcaccg taacggggtt cctgtatacg gtacactctt cttcaactgg tctaatagta
     2941 ttgcagatca agaaagattt gctgaagctt tgaagcaaga cgcagatggt agcttcccaa
     3001 ttgcccgtaa attggtagac atggccaagt attatggcta tgatggctat ttcatcaacc
     3061 aagaaacaac tggagatttg gttaaacctc ttggagaaaa gatgcgccag tttatgctct
     3121 atagcaagga atatgctgct aaggtaaacc atccaatcaa gtattcttgg tatgatgcca
     3181 tgacctataa ctatggacgt taccatcaag atggtttggg agaatacaac taccaattca
     3241 tgcaaccaga aggagataag gttccggcag ataacttctt tgctaacttt aactgggata
     3301 aggctaaaaa tgattacact attgcaactg ccaactggat tggtcgtaat ccttatgatg
     3361 tatttgcagg tttggaattg caacagggtg gttcctacaa gacaaaggtt aagtggaatg
     3421 acattttaga cgaaaatggg aaattgcgcc tttctcttgg tttatttgcc ccagatacca
     3481 ttacaagttt aggaaaaact ggtgaagatt atcataaaaa tgaagatatc ttctttacag
     3541 gttatcaagg agaccccact ggccaaaaac caggtgacaa agattggtat ggtattgcta
     3601 acctagttgc ggaccgtacg ccagcggtag gtaatacttt tactacttct tttaatacag
     3661 gtcatggtaa aaaatggttc gtagatggta aggtttctaa ggattctgag tggaattatc
     3721 gttcagtatc aggtgttctt ccaacatggc gctggtggca gacttcaaca ggggaaaaac
     3781 ttcgtgcaga atatgatttt acagatgcct ataatggcgg aaattccctt aaattctctg
     3841 gtgatgtagc cggtaagaca gttcaggatg tgagacttta ttctactaag ttagaagtaa
     3901 ctgagaagac caaacttcgt gttgcccaca agggaggaaa aggttctaaa gtttatatgg
     3961 cattctctac aacttcagac tacaaattcg atgatgcaga tgcatggaaa gagctaaccc
     4021 tttctgacaa ctggacaaat gaagaatttg atctcagctc actagcaggt aaaaccatct
     4081 atgcagtcaa actatttttc gagcatgaag gtgctgtaaa agattatcag ttcaacctcg
     4141 gacaattaac tatctcggac aatcaccaag agccacaatc gccgacaagc ttttctgtag
     4201 tgaaacaatc tcttaaaaat gcccaagaag cggaagcagt tgtgcaattt aaaggcaaca
     4261 aggatgcaga tttctatgaa gtttatgaaa aagatggaga cagctggaaa ttactaactg
     4321 gctcatcttc tacaactatt tatctaccaa aagttagccg ctcagcaagt gctcagggta
     4381 caactcaaga actgaaggtt gtagcagtcg gtaaaaatgg agttcgttca gaagctgcaa
     4441 ccacaacctt tgattggggt atgactgtaa aagataccag cctaccaaaa ccactagctg
     4501 aaaatatcgt tccaggtgca acagttattg atagtacttt ccctaagact gaaggtggag
     4561 aaggtattga aggtatgttg aacggtacca ttactagctt gtcagataaa tggtcttcag
     4621 ctcagttgag tggtagtgtg gatattcgtt tgaccaagcc acgtaccgtt gttagatggg
     4681 tcatggatca tgcaggggct ggtggtgagt ctgttaacga tggcttgatg aacaccaaag
     4741 actttgacct ttattataaa gatgcagatg gtgagtggaa gctagctaag gaagtccgtg
     4801 gtaacaaagc acacgtgaca gatatcactc ttgataaacc aatcactgct caagactggc
     4861 gcttgaatgt tgtcacttct gacaatggaa ctccatggaa ggctattcgt atctataact
     4921 ggaaaatgta tgaaaagctt gatactgaga gtgtcaatat tccgatggcc aaggctgcag
     4981 cccgttctct aggcaataac aaggtacaag ttggcttttc agatgtaccg gctggagcaa
     5041 ctattactgt ttatgataat ccaaattctc aaactccgct tgcaaccttg aagagcgaag
     5101 ttggaggaga cctagcaagt gcaccattgg atttgacaaa tcaatctggt cttctttatt
     5161 atcgtaccca gttgccaggc aaggaaatta gtaatgtcct agcagtttcc gttccaaaag
     5221 atgacagaag aatcaagtca gtcagcctag aaacaggacc taagaaaaca agctacgccg
     5281 aaggggagga tttggacctt agaggtggtg ttcttcgagt tcagtatgaa ggaggaactg
     5341 aggacgaact cattcgccta actcacgcag gtgtatcagt atcaggtttt gatacgcatc
     5401 ataagggaga acagaatctt actctccaat atttgggaca accggtaaat gctaatttgt
     5461 cagtgactgt cactggccaa gacgaagcaa gtccgaaaac tattttggga attgaagtaa
     5521 gtcaggaacc gaaaaaagat tacctagttg gtgatagctt agacttgtct gaaggacgct
     5581 ttgcagtggc ttatagcaat gacaccatgg aagaacattc ctttactgat gagggagttg
     5641 aaatttctgg ttacgatgct caaaagactg gtcgtcaaac cttgacgctt cattaccaag
     5701 gccatgaagt tagctttgat gttttggtat ctccaaaagc agcattgaac gatgagtacc
     5761 tcaaacaaaa attagcagaa gttgaagctg ctaagaacaa ggtggtctat aactttgctt
     5821 catcagaagt aaaagaagcc ttcttgaaag caattgaagc ggccgaacaa gtgttgaaag
     5881 accatgaaac tagcacccaa gatcaagtca atgaccgact taataaattg acagaagctc
     5941 ataaagctct gaatggtcaa gagaaattta cggaagaaaa gacagagctt gatcgcttaa
     6001 caggtgaggt tcaagaactc ttggctgcca aaccaaacca tccttcaggt tctgccctag
     6061 ctccgcttct tgagaaaaac aaggccttgg ttgaaaaagt agatttgagt ccagaagagc
     6121 ttacaacagc gaaacagagt ctaaaagatc tggttgcttt attgaaagaa gacaagccag
     6181 cagtcttttc tgatagtaaa acaggtgttg aagtacactt ctcaaataaa gagaagactg
     6241 tcatcaaggg tttgaaagta gagcgtgttc aagcaagtgc tgaagagaag aaatactttg
     6301 ctggagaaga tgctcatgtc tttgaaatag aaggtttgga tgaaaaaggt caagatgttg
     6361 atctctctta tgcttctatt gtgaaaatcc caattgaaaa agataagaaa gttaagaaag
     6421 tatttttctt acctgaaggc aaagaggcag tagaattggc ttttgaacaa acggatagtc
     6481 atgttatctt tacagcacct cactttactc attatgcctt tgtttatgaa tctgctgaaa
     6541 aaccacaacc tgctaaacca gcaccacaaa acacagtcct tccaaaacct acttatcaac
     6601 cggcttctga tcaacaaaag gctcctaaat tggaagttca agaggaaaag gttgcctttc
     6661 atcgtcaaga gcatgaaaat gctgagatgc tagttgggga acaacgagtc atcatacagg
     6721 gacgagatgg actgttaaga catgtctttg aagttgatga aaacggtcag cgtcgtcttc
     6781 gttcaacaga agtcatccaa gaagcgattc cagaaattgt tgaaattgga acaaaagtaa
     6841 aaacagtacc agcagtagta gctacacagg aaaaaccagc tcaaaataca gcagttaaat
     6901 cagaagaagc aagcaaacaa ttgccaaata caggaacagc tgatgctaat gaagccctaa
     6961 tagcaggctt agccagcctt ggtcttgcta gtttagcctt gaccttgaga cggaaaagag
     7021 aagataaaga ttaaatatcg aaaaatcttg tgaaatcttt ccttatattt ccaaagtgtg
     7081 atataatagt ttcgaataaa ataaataaag gagtttttgt aacatggcaa aacttactgt
     7141 taaagacgtt gacttgaaag gtaaaaaagt cctcgttcgt gttgacttca acgtaccatt
     7201 gaaagatggc gtaatcacta acgataaccg tatcacagca gctcttccaa ctattaagta
     7261 catcatcgaa caaggtggac gtgcaattct tttctctcac cttggacgtg tgaaagaaga
     7321 agctgataaa gctggtaaat cacttgctcc tgtagcagct gacttggcag caaaacttgg
     7381 tcaagatgtt gttttcccag gtgtcactcg tggtgctgaa ttggaagcgg caatcaacgc
     7441 tcttgaagat ggacaagttc tcttggttga aaacactcgt tacgaagatg ttgacggcaa
     7501 gaaagaatct aaaaacgatc ctgaacttgg taaatactgg gcatcacttg gagatggtat
     7561 cttcgtaaac gatgcattcg gtacagctca ccgtgcacac gcatctaacg ttggtatctc
     7621 agcaaacgtt gaaaaagcag ttgctggttt ccttcttgaa aacgaaattg cctacatcca
     7681 agaagcagtt gaaactccag aacgtccatt cgtggctatc cttggtggtt caaaagtttc
     7741 agacaagatc ggtgttatcg aaaacttgct tgaaaaagct gataaagtcc ttatcggtgg
     7801 tgggatgact tacacattct acaaagcaca aggtatcgaa atcggtaact cacttgtaga
     7861 agaagacaaa ttggatgttg cgaaagctct tcttgaaaaa gcaaatggta aattgatctt
     7921 gccagttgac tcaaaagaag ctaacgcatt tgctggttac actgaagtgc gtgacactga
     7981 aggtgaagca gtttctgaag gcttccttgg tcttgacatc ggtccaaaat ctatcgccaa
     8041 atttgacgaa gctttgactg gtgccaaaac agtcgtatgg aacggaccta tgggtgtatt
     8101 tgaaaaccca gatttccaag ctggtacaat cggtgtgatg gacgctatcg tgaaacaacc
     8161 aggagttaaa tcaatcatcg gtggtggtga ctcagctgcc gcagcgatta accttggccg
     8221 tgcagacaag ttctcatgga ttagtacggg tggtggagca tcaatggaac ttcttgaagg
     8281 taaggttctt ccaggacttg cagccttgac agaaaaataa gattttataa ataaatcaaa
     8341 gaagagaggg atgaaagttc ctcttttctt ttgcttaaaa taaaaacgct tcctctcaac
     8401 tattactcat aaaaatcacc gatttatgat aaaatggaaa tagaaagttg agattatgag
     8461 ttattttaaa aaatataaat tcgataaatc ccagttcaaa cttggtatgc gaacctttaa
     8521 aacaggtatt gctgtttttc tagttctctt gatttttggc ttttttggct ggaaaggtct
     8581 tcaaattggt gctttgacag ccgtttttag cctgagggag agttttgatg agagtgttca
     8641 ttttgggact tcgcgtattc taggaaatag tatcggtgga ctctatgcct tggtcttctt
     8701 cttattaaat acctttttcc acgaagcctt ttgggtgacc ttggtagttg ttccaatctg
     8761 caccatgtta accattatga caaatgtagc catgaataac aaagcagggg ttattggtgg
     8821 tgtagcagct atgttaatca ttaccctatc aattccaagt ggtgagacaa ttttgtacgt
     8881 gtttgtgcgt gtattagaaa cgtttatggg agtttttgtc gcaattatcg taaattacga
     8941 tattgatcgt attcgtctct ttttagagaa aaaagaaaaa taatgttaca ttttataaca
     9001 ttatcaattg acgtttgtct ttttttagac tataatagac agaaagaagg aaattgtaaa
     9061 tgaaggaaaa agaatttcgc cgaaatatgg ctgtttttcc tatcggcagt gttatgaagt
     9121 tgaccgatct atcggcgcgt cagattcgtt attatgaaga tcaagagttg atcaagcccg
     9181 atcgaaacga aggaaatcgt cgcatgtatt ccttgaatga catggatcgt ctgcttgaaa
     9241 tcaaagatta tatctctgaa ggttataata tcgctgccat taagaaaaaa tatgctgaac
     9301 gtgaagcgaa atccaagaaa gcggttagtc agactgaagt acgtcgtgca cttcacaatg
     9361 aactcctcca acaggggcgt tttgcttcag tacagtcacc ttttggtcgc ggttaggcaa
     9421 ccgcaagtag tcatagatta aggagaaaac ttatgccaat cacagctgca gatattcgtc
     9481 gtgaagtcaa ggaaaaaaat gttaccttta ttcgtcttat gttctcagat attttgggaa
     9541 ccatgaaaaa cgtcgaaatt cctgctacag atgaacagtt agataaggtc ttgtcgaaca
     9601 aggttatgtt tgatggatct tctattgaag gttttgtacg tatcaatgag tcggatatgt
     9661 acttgtaccc ggacttggat acatggacag tcttcccttg gggagatgaa aatggaagtg
     9721 ttgcaggtct gatctgtgat gtctatacaa cagaaggtga accatttgcg ggtgaccctc
     9781 gtggtaattt gaaacgagct cttcgtcaca tggaagaagt tggattcaaa tccttcaacc
     9841 ttggtccaga gccagaattc ttcctattta agttggatga aaatggggac ccaacacttg
     9901 aagtgaatga caagggtggc tactttgatt tggcacctac tgaccttgcg gacaacacac
     9961 gtcgtgagat tgtgaatgtc ttgaccaaaa tgggatttga agtagaagcg agtcaccacg
    10021 aggttgcggt tggacagcat gagattgact ttaagtacga tgaagttctc cgtgcttgtg
    10081 ataagattca aatctttaag cttgttgtta aaaccattgc tcgcaaacac ggactttacg
    10141 caacatttat ggcgaagcca aaatttggta ttgctggatc aggtatgcac tgtaatatgt
    10201 ccttgtttga tgcagaagga aataacgcct tctttgatcc aaatgatcca aaaggaatgc
    10261 agttgtcaga aacagcttac catttcctag gcggtttgat caagcatgct tacaactata
    10321 ctgccatcat gaacccaaca gttaactcat acaaacgttt ggttccaggt tatgaagcgc
    10381 ctgtttacat tgcttgggct ggtcgtaacc gttcgccact tgtgcgcgta cctgcttcac
    10441 gtggtatggg aactcgtctt gagttgcgtt cagtggatcc aatggcgaac ccttacgttg
    10501 ctatggctgt tcttttggaa gttggtttgt atggtattga aaataaaatc gaagcaccag
    10561 ctcctatcga agaaaatatc tacatcatga cagcagaaga gcgcaaggaa gctggtatta
    10621 cagaccttcc atcaactctt cacaacgctt tgaaagcttt gacagaagat gaagtggtta
    10681 aagctgctct cggagatcac atctatacta gcttccttga agccaaacga atcgaatggg
    10741 caagttatgc aaccttcgtt tcacaatggg aaattgataa ttatttagac ctttactaat
    10801 actaatatag aagaaagatt gcctgtgggt aaacagtcac acagcagtct aagccatcaa
    10861 atacctataa cccttaaaat agcgatttcg gtcgctattt atttttcgaa aaatcctctt
    10921 gactcttttg cgaattagat ttatcatcag acgtgtagaa gaaaattaag gagtcactat
    10981 ggaaaaattc aatttcaaaa acaatatcgg gcaagaaaac aagttacttc aaatcgaaat
    11041 ctacaagttt actaactttt gcaagcttca aaattacaca tctgtaaata ttttttcgaa
    11101 agatatattt gaagccatag taaattgaga ctagaatagt acactacatc tgctaaaaat
    11161 ttctagaaac taatttaact ttcctaatcg atttgtttac atcttatttc aatctactat
    11221 attatctcaa taaatgatga tggcgactgt tttgtttgtg cttgtcgatt tttgaatcct
    11281 gatcgagcgg aagaatattt ctgccgaggt tgccaagggg aaaatcctga agatattgaa
    11341 ttttatgatg aacaattaca ggcagaaaag gtggaggttt tgaatattcg attggaagta
    11401 aaaaattgaa ttatctacaa tctcatcaac aataaaccta tttcaacccc attatctata
    11461 ggcgtatttt tacgcctttt tatatacttg aagcacata
//
LOCUS       DAVLTG010000054        11396 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLTG010000054 DAVLTG010000000
VERSION     DAVLTG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.055"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(56..286)
                     /locus_tag="VYN12_001719"
     CDS             complement(56..286)
                     /locus_tag="VYN12_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1416049.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYN12_001720"
     CDS             complement(454..1098)
                     /gene="pcp"
                     /locus_tag="VYN12_001720"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1416050.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(1113..2036)
                     /locus_tag="VYN12_001721"
     CDS             complement(1113..2036)
                     /locus_tag="VYN12_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1416051.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPTALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(2033..2722)
                     /locus_tag="VYN12_001722"
     CDS             complement(2033..2722)
                     /locus_tag="VYN12_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1416052.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(2787..3491)
                     /locus_tag="VYN12_001723"
     CDS             complement(2787..3491)
                     /locus_tag="VYN12_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1416053.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(3547..4569)
                     /locus_tag="VYN12_001724"
     CDS             complement(3547..4569)
                     /locus_tag="VYN12_001724"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1416054.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(4701..7172)
                     /gene="parC"
                     /locus_tag="VYN12_001725"
     CDS             complement(4701..7172)
                     /gene="parC"
                     /locus_tag="VYN12_001725"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1416055.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQIGIVPILSSYIAHRREVILARSRFDKEKSEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(7592..9535)
                     /gene="parE"
                     /locus_tag="VYN12_001726"
     CDS             complement(7592..9535)
                     /gene="parE"
                     /locus_tag="VYN12_001726"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1416056.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            9671..10312
                     /gene="plsY"
                     /locus_tag="VYN12_001727"
     CDS             9671..10312
                     /gene="plsY"
                     /locus_tag="VYN12_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1416057.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(10355..11396)
                     /locus_tag="VYN12_001728"
                     /pseudo
     CDS             complement(10355..11396)
                     /locus_tag="VYN12_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3230 a         2550 c         2014 g         3602 t
ORIGIN      
        1 ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt
       61 ttgctaaatt ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac
      121 tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga
      181 taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt
      241 tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt
      301 cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct atatcaggct
      361 tctctgatat agagttttat gtaaacaacc tcaatcgatt tagcatagct aatagttagt
      421 aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg
      481 caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc ctcttacaat
      541 atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg
      601 aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg
      661 gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc
      721 ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc
      781 tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc
      841 atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc
      901 aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga
      961 cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg
     1021 taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc
     1081 tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat
     1141 atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac gccattctga
     1201 tctttcatat ccatcaatgc tgttggtaga gcgttaaaat tagcagccat tggggtcaat
     1261 aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc
     1321 agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca
     1381 tttcccataa tcattgtgaa tagaaccatt ccaagaacat aggccaaaac tcctataaag
     1441 cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc aacacctgct
     1501 acagtaaaaa tagcccccaa agcccctaat aattgaggaa caataccact tgttgaaact
     1561 tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca
     1621 agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga
     1681 atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta
     1741 tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg
     1801 atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc
     1861 atatttggca tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat
     1921 gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat
     1981 tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt
     2041 gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc
     2101 ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat
     2161 tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta
     2221 caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgcagccgca cgcgctttta
     2281 ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc
     2341 ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga
     2401 aaccagctaa ctctcgaata aaaaaataaa ctgtatagaa gtttccaact gtcagacctt
     2461 taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca
     2521 caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca
     2581 aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta
     2641 agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg attgctattc
     2701 ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa
     2761 aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat
     2821 ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt atattctttt
     2881 gttgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc ccccttaata
     2941 ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg agaaccacca
     3001 gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc tttggcatat
     3061 ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa caatttctta
     3121 tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt aataccaagg
     3181 tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc tggatcttga
     3241 tagcttggag cccatcctgt actattcaaa tcatagtctt tttgagaagg agcaacattg
     3301 ccgtatttat cattttccat caaaccatca ataacatttc caataacgtc tgtcctcgat
     3361 gttcgagtcg ctatactgta gcccaatgat gctggatcta ctgcatagac ataagaaaat
     3421 gttgtcggtg catctgcttc tttatcagtt tttccacaag ccactaaaat agctgacgtg
     3481 ctcaggacca ctcctgctgt taagagccac tttttctatt tcataaaaaa tctcctttgg
     3541 tttattttaa tctactttta caatccaacc ttctggcgct tcaatatcgc caaactgaat
     3601 acccgtcaat tcattatata atttacgcgt cacaggacct acttctgttt cactatagaa
     3661 tacatggaaa tcatcaccat gttgaatacc tccaattgga gaaataaccg ctgctgtacc
     3721 acaggcacct gcctctacaa aacggtcaag attatcaatt ggaacatcac cctcaatagg
     3781 agttaatccc aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa tagatggcaa
     3841 gatagatgga ctcaatggtg ttacaaattc attatcagct gtaattccaa agaagttagc
     3901 tgatccgact tcttcaatct ttgtatgagt tgatgggtcc agatagataa catctgagaa
     3961 atgacgtgac ttggccattt ttcctggtaa gagacttgca gcatagtttc caccaacctt
     4021 agccgcacct gtaccatttg gtgctgcacg gtcgtactca tcctgaatca agaagttggt
     4081 tgggaccaaa ccacctttaa agtaatttcc aactggcata gcaaagatgg tgaaaatgta
     4141 ctcttctgcc ggttttaccc cgataatatc tccgacacca atcaaaagag ggcgaagata
     4201 taaggttcca cctgttccgt atggtggtac gtattcttca ttcgcacgga caactgcttt
     4261 acaagcttct acaaacatgt ctgtcggaac ttgtggcatc aagagacggt cacatgtacg
     4321 ttgcagacgt ttagcatttt catcaggacg gaacagttga acactgccat ccttagtacg
     4381 ataagctttc aaaccttcaa atgcttgttg tccatagtga agacttggag aagactctga
     4441 aatatgcaaa gttgcatcct ctgtaagctc tccttgatcc cattgtccat ttttgaaatg
     4501 agcaagatag cgataaggta atttcatata ggaaaaaccg aggttttccc aatcaatcgt
     4561 tactgtcata ttccactcct tattctaaaa acctatttct tatattctac actatttttc
     4621 taaaacagca agtatatttt gtaattttca gaaaatttct ccaataaaaa ccagctctta
     4681 gaactgattc ttcatttcac ttatttatct tcagtaacta cttcctgaag ataagcgtca
     4741 aaaacttctt catctgaaat cgtgtcagaa atgaagcttc cattgctagt gcgttctgac
     4801 aagttcaagt cttgcaatcg gctttcatag attgttcctt tattggattg gacaagcaga
     4861 gtttggtcgt tcacatccac ttccgtactg aagaaatcgc caacaaatcc ttgctctgca
     4921 actgctcctg ccaagaagac acgatgcggt ttgtttttca actcacgcaa gacttgtaat
     4981 cctcgtttgg cacggctggt tgctagaatt tcctcaatgg aaacacgttt caagcttcca
     5041 cgctgggtca agaggtagaa ggacgaagta ttacagataa agccagattg gaggacatca
     5101 tcttctttca aattcatagc cttgacacct gctgccttag caccgacaac cggaacctct
     5161 tcgatattga aacgcagggc ataaccattt tgactaacca agacaacatc atctagttta
     5221 atcggagcca ctgctacaat ctgatctgta tcgtctttga gcttagcata cttgacagac
     5281 ttagatctat aggtccgcca tggagtgaat tcttttcgct ctacccgttt gatttgacca
     5341 aggcgagtca ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac ttccacataa
     5401 aggatttctt cattcgtttc aaagtttgtg atggtttggc tcagatgctc tccgatgtcc
     5461 ttccaacgaa tatctgccaa ctcatggatt ggtctgtaga tgacatttcc aagacttgtg
     5521 aacatcaaga ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg gtcatcatca
     5581 cgcttgccaa tttcttccaa ggtggaagcc gcaaaggaac gtggactggt acgcttgatg
     5641 taacctgcct tggtcacgct gacgtaggta tcttcctcag cgataagact agctgtatca
     5701 atctcaattg ctttcgcagt gtcttctaaa gaactcaaac gaggagttgc aaatttcttc
     5761 ttgacctcac gaagttcttt cttcatgaga ttgtacatag tcctttcatc accgataata
     5821 gccgccagca tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa gacaaccaca
     5881 tcggtattgg tcaaacggta cagttgcaaa gttacgatag cctcagcctg ttcttccgta
     5941 aaatcatagc taactttgag gttttccttg gcgtccgcct tattctcaga agcacggata
     6001 agagcaatga cttcatccaa aatcgaaatc acacgaatca aaccttcgac gatatggaga
     6061 cgtttctcag acttttcttt gtcaaagcgt gaacgcgcca aaatcacttc tcgacggtga
     6121 gcgatatagc tagacaggat tggaacaatc ccaatctgac gaggtgtgaa attgtcaatc
     6181 gccaccatat taaagttgta gttgatttgt aggtcggtgt acttaaataa gtagttgaga
     6241 acaagctcag tattagcgtc tttcttaagt tcgatagcga tacgaagacc atcacggtca
     6301 gactcatcac gaacctcagc aatcccagct accttgttat taacacgaac atcatcgatt
     6361 ttcttgacta gattggcctt attgatttca taaggaatct cagtaataac gatttgttcc
     6421 ttaccacctt ttagcttttc aatttcagtc ttggaacgaa caaccacgcg ccctttccca
     6481 gtctcataag ctttcttgat ttcatcacga ccctgaataa tagcccctgt agggaagtct
     6541 ggtccaggca agaattccat gagtttatca atctttgcag ttgggtggtc aatcatgtaa
     6601 actgcagcat ctatgacctc agctaaatta tggggaggaa tgtctgtggc ataaccagcc
     6661 gaaatcccag tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa gaccgttggt
     6721 tctttctccg tatcgtcaaa gttccatgca aaaggaactg tctttttctc gatatcctga
     6781 agaaggtagc ctgcaatttc agacaaacgt gcctcagtat aacgcatagc cgcaggagga
     6841 tctccgtcca tagaaccgtt attaccgtgc atttcaacta gaatctcacg atttttccag
     6901 ttctgtgaca tacgaaccat ggcatcatag atagaagaat ccccgtgtgg gtggaaattc
     6961 cccatgatgt tcccgactga cttggccgac ttacggtagc tcttgtcaaa agtattgcta
     7021 tccttattca tagaataaag aatacggcgt tgaaccggct tcaacccatc acgaatatct
     7081 ggcaaagccc ggtcttgaat aatgtacttg gagtagcgac caaagcgctc tcccatgatg
     7141 tcctccaggg acatgttttg aatgttagac ataagataca aagcccataa aataccaagt
     7201 gaaaatagaa aattcttgaa gtaagcaaac tcacaagaga atttatcttt ttcacacagt
     7261 atctagggcg tgttcaactc ctttcaaaga atgtagagta ggtttttatg cagtaaaaga
     7321 tattttacgg gaattcctcc cgtgttcagt tacgataagt aaccaaacta tcctgtttgt
     7381 atttttcaat atgaaaatct ggttttccaa aattagtctt agtttgtgtc ttaaccgctc
     7441 ccttaagcgc ctctttaaga taagcactca tagcagattc ttcattaata atcctgcaat
     7501 tttttcaaac caagattttc aaactgcttt ttcacatagt cattcacatc cgactctaat
     7561 ttccagttta ctaacatatt attttctttc attaaaacac tgtcgcttct tctagcgtaa
     7621 acttgacatt atcttcaatc catttacggc gtggttctac cttatctccc atgagaacat
     7681 tgacgcggcg ttcggcgcgc gctaaatctt caattgtgac acggatgagg gtacgtgttt
     7741 ctgggttcat ggttgtttcc cagagctggt ccgcattcat ctcaccaagt cctttgtatc
     7801 gttggagggt agcgccttta ccgaactgtt tacggagttc ttctagttct ccatccgtcc
     7861 aagcgtaggc cacttcttct ttcttgcctt tacctttgga catcttgtaa agaggtggga
     7921 gggcaatata gacatgacct gcctcgacta gcggacgcat gtaacggtag aaaaatgtca
     7981 agagcaaggt ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata atgatcttat
     8041 catagttggc atcttcaata gagaagtctg ctccaacacc cgcaccaatg gtataaatca
     8101 tggtattgat ctcttcattt ttgaggatat ccgccatctt ggccttggct gtattgacaa
     8161 ccttaccacg aagaggtaga atagcctgga acttgcggtc acgaccttgt ttggcagaac
     8221 caccggcaga gtccccctca actagataga gttcattctt agcaggattc ttagattggg
     8281 ctggggtcaa tttcccagac aacaagccct tatctttctt gtttttcttc ccatttcggc
     8341 tctcatcacg cgccttacgt gctgcttcac gagcatcacg ggccttgata gccttgcgga
     8401 tgaggttaga agctaattcc ccattttcca taaggaaaaa ggtcaactta tcagccacta
     8461 ttccatccac aactgggcga gctagggggc ttcctagttt atccttggtc tgtccttcaa
     8521 actgcaagtg ttcttcagga actaagatag aaagaacggc cgctagtccc tcacgatagt
     8581 ctgaaccttc aaggttttta tctttttcct tgagaagacc tgttttacgt gcatagtcat
     8641 tcatgacctt ggtaatggca gacttgagtc ctgtctcgtg cgttccaccg tccttggtgc
     8701 gaacgttatt gacaaaggat agaatgttat ctgagaatcc gtcattgtac tggagggcta
     8761 cttccacttg aaaaccattg tcttcccctt caaagtaaag aactggcgtc aagatttcct
     8821 tatcttcgtt gagataagaa acaaaatctt gtactccatt ctcatagtgg aactcaatcg
     8881 cttcatctgt tcgcttgtcc gttaaagaca aggtcacatt tttcaagaga aaggctgatt
     8941 cattaaggcg ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag atagtcgcgt
     9001 caggcataaa agtaactttg gtgcctgttt tagacttggg tgctgtaccg attttcttca
     9061 aagtcgtgac aggttttcca ccattttcaa aacgttgctt gtaaactgcg ccatcacggg
     9121 taatttcaac ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc actccgtgaa
     9181 gtccacctga tgtcttatag ccaccttgac cgaatttccc tccggcatga agaatggtaa
     9241 agataacctc aacagttgga attcccatag cgtgcatacc tgtcggcatc ccacgtccat
     9301 ggtcttgaac cgttagacta ccgtctttat tgatagttac atcaatacga tcaccaaacc
     9361 cagacaaggc ttcatcgact gcattatcaa cgatttccca aactaggtga tgaagaccag
     9421 cgccatcggt cgatccaata tacatccctg gacgttttcg gaccgcatcc aacccttcta
     9481 gcacctgaat agcatcatca ttataattgt taatattgat ttcctttttt gacacaagga
     9541 acctcctatt cgttcatctt tactattcta caggttttcc aaggattttg caaaattttt
     9601 ctttctccga tgtgacaatt ttagcagaga ttctctgctt ttctttccca attcatgata
     9661 taataggagt atgattacaa tagttttatt aatcctagcc tatctgctgg gttcgattcc
     9721 atctggtctc tggattggac aagtattctt tcaaatcaat ctacgcgagc atggttctgg
     9781 taacactgga acgaccaata ccttccgcat tttaggtaag aaagctggta tggcaacctt
     9841 tgtgattgac tttttcaaag gaaccctagc aacgctgctt ccgattattt ttcatctaca
     9901 aggcgtttct cctctcatct ttggactttt ggctgttatc ggccatacct tccctatctt
     9961 tgcaggattt aaaggtggta aggctgtcgc aaccagtgct ggagtaattt tcggatttgc
    10021 gcctatcttc tgtctctacc ttgcgattat cttctttgga gctctctatc ttggcagtat
    10081 gatttcactg tctagtgtca cagcatcgat cgcggctgtt atcggggttc tgctctttcc
    10141 actttttggt tttatcctga gtaactatga ctctctcttc atcgctatta tcttagcact
    10201 tgctagtttg attatcattc gtcataagga caatatagct cgtatcaaaa ataaaactga
    10261 aaatttggtc ccttggggat tgaacctaac ccatcaagat cctaaaaaat aaaacgccag
    10321 ttctgtactg cccccaaaca gttagacaat taatttatcc gaaggattta gttctgtatt
    10381 gcacagggct aagtcctttt agttttacct taattctctt attgttgtaa taatcaatat
    10441 agtctataat ggcttgttcc aattgcttaa gcgactgaaa cgacttctca taaccgtaaa
    10501 acatttccga tttcagaatc ccaaagaagg actccatcat accgttgtct gggctgtttc
    10561 ccttgcgtga tatggatgct tgaattccct tactctctag gaaccgatga taagaatcgt
    10621 gttggtattg ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctgtga
    10681 atgcctgttc caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg
    10741 cgataatttc gctattaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg
    10801 ctggaatggc aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa
    10861 attggccttg aatgagattc tctgccttct tgccaacgtc tcctttatga gaagaatatt
    10921 ttcgtttctg tcgcatttta gcttgtaaat tgagtacttt catcaagcct tgaactcttt
    10981 tatggtttac cagataacca cgatttctta gttctaaatg aacccggcga taagtataat
    11041 ttcccttgtg ttcgataaaa atggattgaa tttcagcttt aagctcttgg tccttatctg
    11101 gtttgtctag ctgtttcaag tgatagtagt aggtcgaacg agctagttta atggctttta
    11161 gaagaatatc taacgaaaac tcagtcatta attcttgaac aatttctgtc tttcttcttt
    11221 ctctttttcc tccttcaatc ggagttctct taactttttt aggatggcat tctccgctct
    11281 caggtactca ttttctgctt gaagatattc taattctgtc ctctcttcag gtctcttttt
    11341 tggcttacgt cccattttag gtactctccc tcttgttttc tcaacaatag tatacc
//
LOCUS       DAVLTG010000055        10774 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLTG010000055 DAVLTG010000000
VERSION     DAVLTG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.056"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            132..629
                     /locus_tag="VYN12_001729"
     CDS             132..629
                     /locus_tag="VYN12_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1416058.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            629..2284
                     /gene="dnaX"
                     /locus_tag="VYN12_001730"
     CDS             629..2284
                     /gene="dnaX"
                     /locus_tag="VYN12_001730"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1416059.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2312..2506
                     /locus_tag="VYN12_001731"
     CDS             2312..2506
                     /locus_tag="VYN12_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1416060.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2656..3426
                     /gene="sufC"
                     /locus_tag="VYN12_001732"
     CDS             2656..3426
                     /gene="sufC"
                     /locus_tag="VYN12_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1416061.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3454..4716
                     /gene="sufD"
                     /locus_tag="VYN12_001733"
     CDS             3454..4716
                     /gene="sufD"
                     /locus_tag="VYN12_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1416062.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGDDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4727..5953
                     /locus_tag="VYN12_001734"
     CDS             4727..5953
                     /locus_tag="VYN12_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1416063.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5940..6380
                     /locus_tag="VYN12_001735"
     CDS             5940..6380
                     /locus_tag="VYN12_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1416064.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6434..7846
                     /gene="sufB"
                     /locus_tag="VYN12_001736"
     CDS             6434..7846
                     /gene="sufB"
                     /locus_tag="VYN12_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1416065.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8077..9318)
                     /locus_tag="VYN12_001737"
     CDS             complement(8077..9318)
                     /locus_tag="VYN12_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1416066.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9421..10530
                     /locus_tag="VYN12_001738"
     CDS             9421..10530
                     /locus_tag="VYN12_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1416067.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3199 a         1968 c         2341 g         3266 t
ORIGIN      
        1 tacacaaaaa taggctccat aatatccata ggggatttac ccactacaaa tattatagag
       61 cccaaaatcc tttgtttact aaacaaggga tttttctttt gtctctgctc cttttttgat
      121 ataatagttc tatgttaaaa tcagaaaaac aatcacgtta tcaaatgtta aatgaagaat
      181 tgtccttcct attggaaggc gaaaccaatg ttttggctaa tctttccaac gccagtgctc
      241 tcataaaatc acgttttcct aataccgtat ttgcaggctt ttatttgttc gatggaaagg
      301 aattggtttt aggccccttc caaggaggtg tttcctgcat ccgtattgca ctaggcaagg
      361 gtgtttgtgg tgaggcagct cactttcagg aaactgttat tgttggagat gtgacgacct
      421 atctcaacta tatttcttgt gatagtctag ctaaaagtga aattgtggtg ccgatgatga
      481 agaatggtca gttacttgga gttctggatc tggattcttc agagattgag gattacgatg
      541 ctatggatcg agattatttg gaacaatttg tcgctatttt gcttgaaaag acagcatggg
      601 actttacgat gtttgaggaa aaatcttaat gtatcaagca ctttatcgaa aatatagaag
      661 tcaaaacttc tcccagttag ttggtcaaga agttgtggct aagactctta aacaagcggt
      721 ggagcaagag aaaataagtc acgcttatct tttttctggt cctcgtggaa cgggaaaaac
      781 cagtgttgct aaaatctttg ccaaggctat gaactgtccc aatcaagtgg gtggcgaacc
      841 ttgcaataac tgctatattt gtcaagcagt gacggacggt agtttagaag atgtcattga
      901 aatggatgca gcttctaata atggggtaga tgaaattcgc gaaattcgtg ataaatctac
      961 ctatgcgcct agccttgctc gttataaggt ttatatcata gatgaggttc acatgctgtc
     1021 tacaggggct tttaatgccc tcctaaagac gctggaagaa ccaacacaga atgtagtctt
     1081 tattttggcc actactgaat tgcacaagat tcctgctact attctatccc gtgtgcaacg
     1141 ttttgagttt aaatcaatta agacacagga tattaaggaa catattcact atatcttaga
     1201 aaaagaaaat atcagttctg aaccagaggc tgtggaaatc attgccagac gggcggaagg
     1261 tggaatgcgg gacgccttgt ctattttgga tcaagccctg agtttgacac agggaaatga
     1321 gctgacgact gctatctctg aagaaattac tggcaccatt agcctatcag ccttggatga
     1381 ttatgtggcg gccttgtctc aacaggatgt tcccaaagct ttgtcttgct tgaatcttct
     1441 ttttgacaat ggtaagagca tgactcgttt tgtgaccgat cttttgcact atttaagaga
     1501 cttgttaatt gttcaaacag ggggagaaaa tactcatcat agttcagtct ttgtagaaaa
     1561 tttggcactt cctcaaaaaa atctgtttga aatgattcgc ttagcaacag tgaatttagc
     1621 agatattaag tctagtttgc agcccaagat ttatgctgaa atgatgaccg tccgtttggc
     1681 ggaaatcaag cccgaaccag ctctatcagg agcggttgaa aatgaaattg ctacgctgag
     1741 acaggaagtt gcccgtctca aacaagagct ttctaatgca ggtgcggttc ctaaacaagt
     1801 tgcaccagct cctagtcgac cagctacggg caaaacagtc tatcgtgtcg atcgcaataa
     1861 agtgcaatct atcttacaag aggccgtcga aaatcctgat ttagcacgtc aaaatctaat
     1921 tcgtttgcag aatgcctggg gagaggtaat tgaaagtcta ggtgggccgg acaaggctct
     1981 gctagttggt tctcaaccgg ttgctgccaa tgaacaccat gctattcttg cttttgagtc
     2041 taacttcaat gctggtcaaa ctatgaaacg agacaatctc aataccatgt ttggtaatat
     2101 cctcagtcag gcggcaggtt tttcacctga gattttagct atttccatgg aggaatggaa
     2161 agaagttcgc gcagcctttt cagccaaagc caaatcttct caaactgaaa aagaagtaga
     2221 agaaagcctg attccagaag gatttgaatt tttggctgat aaagtgaagg tagaggaaga
     2281 ctaaagaaag atttcatgat acaataagtt tatgaataaa caacaattta ttattatggc
     2341 gctatttaca gctgctgaga cctatttttt caatgaagcc tggatgactg gccgctatat
     2401 tatggcagcc ttttgggcaa ttttactctt tagaaatttc cgagtcagtt atgtgatggg
     2461 caaaatcgtt gatgtcatcg atcagcattt taataggaaa gactagccct cagcttccag
     2521 acaaaatcaa agccttttag gctttttttt gttatactag aaaagtatat ttatagaatt
     2581 tttgctctat ttttggggaa atcagacgtt tttctagtaa gtactgtaaa agttttgaaa
     2641 aagaaaggaa ctatcatgtc agtattagag atcaaagatc ttcatgttga gattgaagga
     2701 aaagaaattt taaaaggggt taacctgacc ctgaaaacag gagaaattgc cgctatcatg
     2761 ggaccaaatg gtacaggtaa atcgactctt tctgccgcta tcatgggaaa tccaaactat
     2821 gaagtaacta aaggtgaagt tttgtttgat ggcgtaaaca tccttgagtt ggaagtggat
     2881 gagcgtgcgc gtatgggact tttccttgct atgcaatacc catcagaaat ccctggaatt
     2941 accaatgctg agtttcttcg tgccgctatg aatgcgggta aagaagatga tgagaagatt
     3001 tcagttcgtg agtttattac taagctagat gaaaaaatgg aattgctcaa catgaaagaa
     3061 gaaatggcag agcgttacct caacgaaggc ttctctggtg gtgagaaaaa acgcaatgaa
     3121 attcttcaac ttttgatgtt ggagccaaca tttgctcttt tggatgagat tgactcaggt
     3181 cttgatattg acgctcttaa agttgtgtct aaaggtgtca atgccatgcg tggtgaaggt
     3241 tttggtgcta tgatcattac tcactaccaa cgtcttttga actatatcac acctgatgtg
     3301 gtacacgtga tgatggaagg tcgtgttgtc ctttctggtg gtccagaatt ggctgcgcgt
     3361 ttggaacgtg aaggatacgc aaaactagct gaagaacttg gctacgacta caaggaagaa
     3421 ttgtaattcc ctcgtatctt ttaggagaag taaatgacta gagaaaatat taaacttttt
     3481 tcagaaatgc acgctgaacc aagctggttg gctgatctcc gtcaaaaagc ttttgacaag
     3541 attgagactt tggaattacc agttattgag cgtgtcaaat tccaccgttg gaatctgggt
     3601 gatggaacga ttacagaaaa tgagccatca gcaaatgttc cagatttcac agctttagat
     3661 catcacttga agttggtgca agtaggaact caaactgttt tcgaacaaac tccagttgag
     3721 ttagctgaac agggtgttgt cttcacagac tttcactcag ctttagaaga aattccagag
     3781 ctgatcgaag aattcttcat gtcatctgtt aagtatgatg atgacaagtt ggcggcttac
     3841 cacacagctt actttaacag tggtgctgta ctctatattc cagataacgt agaaattaca
     3901 gagccaattg aaggaatttt ctaccaagat agcgatagca atgtgccgtt taacaagcat
     3961 attatgatta tcgctggtaa aaattctaag attagttatc tggagcgttt agagtcacgc
     4021 ggtgaaggaa gtgacaaagc aactgccaat atcacagtgg aagtgattgc acgttctggt
     4081 gcgcaagtca agtttgctgc tatcgaccgt ctaggtgaaa acgtcactgc ctacattagc
     4141 cgtcgtggta aattaggcga cgatgcaagt attgactggg ctatcggtgt catgaacgaa
     4201 ggaaatgtcg ttgctgattt tgatagtgac ttgattggta atggtagcca tgctgacctg
     4261 aaggttgtag ctctttcaag tggtcgtcag gtacaaggga ttgatactcg tgtaactaac
     4321 tatggctgca actctatcgg aaatatccta caacatgggg ttatccttga aaaagcaact
     4381 ttgactttca atggtatcgg ccacatcatc aagggtgcta agggagcaga tgcgcaacaa
     4441 gagagccgtg ttcttatgct ttcagaccaa gcgcgttcag atgctaaccc aattcttttg
     4501 attgatgaaa atgacgtaac tgcaggacat gcagcctcta ttggtcaggt agatccagaa
     4561 gacatgtatt acctcatgag tcgtggcttg gataaggcaa ctgcagagcg tttggttgtt
     4621 cgtggtttcc ttggatctgt tatcgtggag attccagtca aggaagttcg tgatgaaatg
     4681 attgcaacta tcgaagagaa attgtcaaaa cgctaagggg aagcctatgt tagatgtaga
     4741 agcgattcgc aaggattttc caattttaga tcagattgtc aatgatgaac ctctggtcta
     4801 tctggacaat gctgcgacga cacaaaaacc actagtagtt ctgaaagcta ttaacagcta
     4861 ctatgagcag gacaatgcca atgttcaccg tggtgtccat accttagcgg aacgagcgac
     4921 agcttcttat gaagctgctc gtgaaaccat tcgtaagttt attaatgcag gctctacaaa
     4981 ggaagttctc tttaccagag gaacgacaac cagccttaac tgggtggcac gctttgctga
     5041 ggaaattctc gctgagggag accaggtctt gatttcagta atggaacacc attctaatat
     5101 cattccatgg caggaagctt gtcgaaagac tggagcagag cttgtctatg tctatcttaa
     5161 agacggtgcc ttggatatgg aggatttgcg agctaaattg actgataagg ttaaatttgt
     5221 ttccctagct catgcctcca atgttcttgg tgtggtcaat ccgatcaagg aaatcactca
     5281 attagcccac caagttgggg caattatggt agtggatggt gctcaatcta cacctcatat
     5341 gaagattgat gtccaggact tggatctgga ctttttcgcc ttttcgggtc acaagatggc
     5401 tggtccgact ggtatcggtg tcctttacgg caaagaaaag tatcttgagc aaatgtctcc
     5461 agtagaattt ggcggcgaga tgattgattt tgtctacgag caatttgcta gttggaagga
     5521 attgccttgg aaatttgagg ctggaacgcc aaatatggca ggagctattg gacttgcgac
     5581 tgcagttgat tatctggaaa agattggtat ggatgccgtt gaagctcatg aacaggaatt
     5641 gattgcgtac gtctatccaa aactgcaggc aattgaggga ttgaccattt acggttctca
     5701 ggatttggct caacgttcgg gtgttattgc ctttaaccta ggtgatctcc atcctcacga
     5761 tcttgcgacg gctctggatt atgaaggagt ggctgttcgt gctggtcacc attgtgcgca
     5821 acccttgctt cagtatttgg aagtcccagc aacagctcgt gcaagttttt atatctacaa
     5881 taccaaggca gattgcgaca aactagtcga tgccctacaa aagacaaagg agtttttcaa
     5941 tggcactttc taaactagat agcctttata tggcagtggt agcagaccat tcgaaaaatc
     6001 cacatcacca agggaagtta gaagatgctg agcaaaccag tctcaacaat ccgacttgtg
     6061 gggatgtcat caacctctct gtcaagtttg atgcagagga ccgtttggaa gatattgctt
     6121 ttctaaattc aggatgcacg atttcaactg cttctgctag tatgatgaca gatgccgttt
     6181 taggaaaaac caaacaagaa attttagaac tggcgactat tttttctgaa atggttcagg
     6241 ggcaaaaaga tgagcgtcaa ggccaacttg gagacgcggc attcttgtca ggtgttgcca
     6301 aattccctca aagaatcaag tgtgcaaccc tagcttggaa tgcccttaag aaaacaattg
     6361 aaaatcaaga aaaacagtaa gacaagtttc ttttgtctta tgaattatta gaaatgaaga
     6421 aagaaaggat actatggctg aagaaagagt agaaccaaaa ccaattgacc ttggtgaata
     6481 taaatttggt ttccatgacg atgtagagcc tgtcttatcg acaggaaaag gactcaacga
     6541 aggtgttatt cgtgaattat ctgctgctaa gggtgagcct gagtggatgt tggagttccg
     6601 tttgaagtct tatgaaacct tcaaaaaaat gcccatgcaa acttggggag cagacttgtc
     6661 agagattgac tttgatgact taatctacta ccaaaaacca tctgacaaac cagcccgttc
     6721 ttgggatgat gtacctgaaa agattaaaga aacctttgaa cgtatcggga ttccagaagc
     6781 tgaacgtgct tatttagcag gggcttctgc ccagtacgag tcagaagtgg tttaccacaa
     6841 catgaaggaa gagttccaaa aattaggtat tatctttaca gatacagatt ccgcactcaa
     6901 ggaataccca gacttattta aacaatactt tgcgaagttg gtaccgccga cagataacaa
     6961 gttggcagcc ctcaactcag cagtatggtc gggtggaact tttatctacg tgccaaaagg
     7021 tgtcaaggta gatattccac ttcaaactta tttccgtatc aataacgaaa atataggtca
     7081 gttcgaacgt accttgatta tcgttgatga gggagcaagc gtccactacg tagaaggatg
     7141 tacagcacca acatattcaa gcaatagctt acacgctgcc attgtagaaa tttttgcttt
     7201 ggacggagct tatatgcgtt atacaactat ccaaaactgg tctgataacg tctataactt
     7261 ggtaacaaag cgtgctaagg ctcaaaagga tgccactgtt gagtggattg atggaaactt
     7321 gggtgccaaa acgactatga aatatccatc tgtttacctt gatggagaag gagcgcgtgg
     7381 taccatgctc tctatcgcct ttgctaatgc agggcaacac caagacacgg gtgctaagat
     7441 gattcacaat gctccacata ccagctcgtc tattgtgtct aaatccatcg ctaaaggtgg
     7501 aggaaaggtt gactaccgtg gacaagtcac ctttaacaag aactctaaga aatctgtttc
     7561 ccacattgaa tgtgatacca ttatcatgga tgacttgtca gcatcagata ctattccatt
     7621 taatgaaatt cacaactcgc aagtggcttt ggaacacgaa gccaaagtat ctaagatttc
     7681 agaagagcaa ttgtattatc tcatgagccg tggattgtca gaatctgagg caactgaaat
     7741 gattgtcatg ggatttgtag aaccctttac aaaagaactt ccaatggaat acgcagttga
     7801 gctgaaccgc ttgattagct atgaaatgga gggatcagtt ggataaaatt tgattttata
     7861 ctcttcgaaa atctcttcaa accacgtcag catcgcctta ccgtatgtat ggttactgac
     7921 ttcgtcagtt tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct
     7981 agtttattct ttgattttga gtattagatt tactcaaaat caaggatttt gaagatgaac
     8041 ttgtatcaaa aaatcgcggt ttaaaatcgc gattttttat aatttctcgt taacaaagcg
     8101 gacaaactga ttccaccaaa cttttaagaa gaaggctttt tcaattttct tgtctgctac
     8161 catttcgaaa ctagggcgct ctgtggtgat gtaaccttga ccaatcaagt tcttgtcttc
     8221 ataagtcaaa tggccaacca ctgttccagc ttcaagtggt gctgggattg ctttggaatc
     8281 aggtgtgaat tgaacagatt gggaagattg attcccaaca cgttctatta gatagatatc
     8341 ctctggagcc actgcagtta ctgtatcttc ttttccatct tgtacagggg ctttgctatc
     8401 ttgataggca tcgccttgtt gaacgatttt gcgaagtgta aatgtagaag aaatataatc
     8461 cattagggaa gatgtagctg taaatcgagc gtaaggatta ttgtcttgat gatctgcatt
     8521 taaaacaact gtgatgactc tcatgccttt ttcgacagta gtaccaacaa aagactctcc
     8581 agccttatct gttgttcctg tttttagccc atcaaaacca ccacggtaag caggcatacc
     8641 ttctaacatg tagttggttg aagtgattgt catcccagca aaagtagaag aaggtttttt
     8701 ggtgatttct aagacttgtg ggtatttttt gatgaggttg cgagcaacga tagcgacatc
     8761 ataagcacta agcttatttt cctcatcttt tttagaacct gggtaaatgt tatcccctag
     8821 agtttcattg ttaagacctg tcgtattgac aacagtggca tcctgaattc cccattccaa
     8881 gagttttgcc cgcatcatat cgacgaaatc tttttctgag ccagcaattt tctcagctag
     8941 ggcaatagcg gcgctgttgg cactagatac cagagttgct tcaagcaact cttcgacagt
     9001 ataattacgg gcctccatag gaatattact ggcttcagaa tttgtcgtca attgataagg
     9061 ataatcagaa atatctacag gagtggagag ggtaatactt ccgttttcca aagcttcata
     9121 gaccagataa acagtaatca attttgttat ggaagcaatt tcgacaggtt gcgttgcatc
     9181 cttctcatag agaattttac cagtatttgc ctcaacagca atcgcatgtt tagcggcaat
     9241 ggtaaaatct tgagcaacag cagtagaagc accccctaaa agagagacag ttaacaaagt
     9301 taaaaatatt tttttcatag tagttttatt ctatcataaa gaaaaaaaat attcttgctt
     9361 taataattca tctgttaagc tttttgaaaa tatggtaaaa taaagtgagg gaggtaactc
     9421 atgtttcgta gaaataaatt atttttttgg accacagaaa ttttactctt aaccatcatc
     9481 ttttacctat ggagacagat ggggtctttg attaaccctt ttgttagcgt gcttaataca
     9541 attatgattc catttttatt agggggcttt ctttattatt tgacaaaccc tattgttact
     9601 ttcttaaata aagtctgtaa actcaatcgt ttgcttggta ttttaattac cttgtgtact
     9661 ttggtctggg gaatggtcat aggtgttgtc tatctcttac ctattttgat taatcagtta
     9721 tctagtttga ttatatctag tcaaactatt tatagtcgag tacaagactt aatcatagac
     9781 ttatctaatt atcctgcgct ccagaatttg gatgtagaag ctacaattca gcagttaaac
     9841 ttatcctatg ttgatattct tcaaaatatc ctaaatagcg tatcaaatag tgtggggagc
     9901 gtcttgtcag ctcttatcag tactgttttg attttgatta tgactccagt ttttttggtt
     9961 tatttcttat tagatggaca taaattcttg cccatgcttg aaagaacgat tctaaagagg
    10021 gatcgcttgc atattgcagg cttattaaag aatttaaatg cgacgattgc tcgctatatt
    10081 agtggagttt cgattgacgc aatcattata ggttgtttgg cttatattgg ctatagtatt
    10141 attggtttaa aatatgcttt agtttttgcc attttttctg gtgtagccaa tttaattcct
    10201 tatgtggggc caagtattgg tttgattcct atgatcatcg caaatatatt cactgatccc
    10261 catagactgc tgattgcagt gatttatatg cttgttgttc agcaggtaga tggcaatatc
    10321 ttatatcctc gaatcgtagg aagtgttatg aaggttcatc caatcacgat tttagtttta
    10381 cttttgttgt caagcaatat ctatggtgta gttggaatga ttgtcgcagt gccaacctat
    10441 tctatcttga aagaaatttc taagttctta tcccgtttgt atgaaaatca taaaataatg
    10501 aaagaacgag aaagagaatt agctaagtaa aagtcaggag aaccctgatt tttctttact
    10561 ggaagtggcc tttagattag aagactgaaa ataagttaaa gtcttaaact aattttcaca
    10621 gctaagaata gtagaagtta atctgataaa aatcgaaaaa accagtggaa ttctgtgtca
    10681 gggtaagttc cactggtttt catagtctat taaagttcga atgaaaccta tttatagtag
    10741 attgaaacta gaatagtaca cctctaattc taaa
//
LOCUS       DAVLTG010000056        10730 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLTG010000056 DAVLTG010000000
VERSION     DAVLTG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.057"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..638)
                     /locus_tag="VYN12_001739"
     CDS             complement(<1..638)
                     /locus_tag="VYN12_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1416068.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSK"
     gene            complement(926..1888)
                     /gene="nrdF"
                     /locus_tag="VYN12_001740"
     CDS             complement(926..1888)
                     /gene="nrdF"
                     /locus_tag="VYN12_001740"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1416069.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2076..4235)
                     /gene="nrdE"
                     /locus_tag="VYN12_001741"
     CDS             complement(2076..4235)
                     /gene="nrdE"
                     /locus_tag="VYN12_001741"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1416070.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDEEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4316..4534)
                     /gene="nrdH"
                     /locus_tag="VYN12_001742"
     CDS             complement(4316..4534)
                     /gene="nrdH"
                     /locus_tag="VYN12_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1416071.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4885..5148
                     /locus_tag="VYN12_001743"
     CDS             4885..5148
                     /locus_tag="VYN12_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1416072.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5154..6887
                     /gene="ptsP"
                     /locus_tag="VYN12_001744"
     CDS             5154..6887
                     /gene="ptsP"
                     /locus_tag="VYN12_001744"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1416073.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7142..9592
                     /gene="phtA"
                     /locus_tag="VYN12_001745"
     CDS             7142..9592
                     /gene="phtA"
                     /locus_tag="VYN12_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1416074.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            9750..>10730
                     /gene="phtB"
                     /locus_tag="VYN12_001746"
     CDS             9750..>10730
                     /gene="phtB"
                     /locus_tag="VYN12_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1416075.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMS"
BASE COUNT         3401 a         2005 c         2232 g         3092 t
ORIGIN      
        1 aacttactat gatctgcgag taaatatttt ttattagaat tatttaaagc gatgcgttga
       61 gcctctccct cttcctcgct aaaagtagct agagctccgt tttgaatacc attacagcta
      121 acgaaagctt tagaaaattg gagattagag agattttgta gggtcaatgt gccaacaaaa
      181 gcacctgtaa tatcgcgata atttccacct atcaaaatca aatctgttaa ttttcgttcg
      241 cttaaaatca gaaaaacagg tagactgttg gttacgacgc ggatattgtc aataggcaac
      301 tcacgcgcaa aaaactctaa tgttgttcct ggtccaatga aaatagtttc tctttcttct
      361 actagactgc ctgcaaaatg ggctatttct tgtttttctg ccgtttggag ggcttgtttt
      421 tcaatatttg atcgctcatt agtcaaaagg gagttggttc gaagtttttc agctccacca
      481 tgcacacgaa tcagcaaatc tttatcagct aattcctgta aatagcgcct tgcagtcata
      541 tctgaaacgg ctatttcgtc cataatctgt ttaactgtta tggttccttt actatttact
      601 atctctaaaa ttttggttaa tttttcttgt ttgagcatat tatcacctcg tttcctacta
      661 ctatcttacc ataaacaaac tcatcattca aatacaaaaa caacaaaatg aaacaaaaac
      721 aaaaatatcg aagtttgttt tcaaaacttt cgatattttt gttgggttat tattttgttg
      781 tttctagttt actttttgat ggttaagagt ggtggagaat tatactcaat gaaaatcaaa
      841 gagcaaacta ggaagctagc cgcaggctgt acttgagtac ggcaaggcga agctgacgtg
      901 gtttgaattt gattttcgaa gagtattagt ccaaaccgta gttgtagtca tcatcttgca
      961 tggcttcaac ttcgccaaga aggtaaccat ttccgacttg agagaagaag tcatggttgg
     1021 aagttcctgt tgaaataccg ttcataacga ttgggttgac atcttcagct gaatctggga
     1081 aaagtggatc ttgtcccatg ttcatgagag ctttattggc attgtagcga aggaaggttt
     1141 taacctcttc agtccaacca acaccgtcat aaagactctc tgtgtagcct tcttcatttt
     1201 cataaagagt atagagtagg tcgtacatcc attctttgag tttttcttgc tcttcttcag
     1261 gtaattcatt gaaaccaagt tggaatttgt aaccaatgta ggttccgtga acagactcgt
     1321 cacgaataat caatttaatg atttctgcaa cgttggcaag tttgttgtta ccgagatagt
     1381 agaggggagt gaagaaacca gagtagaaga ggaaggtttc gaggaagacg ctggcaactt
     1441 tcttttcaag tgggctgccg tttaggtaga tttcgttgac aatctcagcc ttcttttgta
     1501 ggtaaggatt ggtattggtc cattcgaaaa tttcttcaat ctcagcctta gtattcaagg
     1561 tagaaaagat tgatgagtaa gatttagcgt ggacagattc cataaattgg atgttattga
     1621 aaacagcttc ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc ccagtttcag
     1681 attgcatagt gtcaagaagg gttaaaccac caaaaacttt tccgaccaag tctttctctt
     1741 tgttagatag ctttctccag tcatccaagt cgtttgataa gggaatacgt gtatcgagcc
     1801 aaaattgctc cgtcagtttt tcccaagttg atttgtcgat gacatcttcg atggcattcc
     1861 agttaatggc tttgtagtaa gtttccattt aaaatctctt tctgtgttta gtattgcgaa
     1921 ctcacaatta tttctacttt accataattc tataggagta tcgcacaaaa agtcggaagc
     1981 ccgactttta aaatgttaca taaattatgt tatgacatag tagatttgat tttatcagtg
     2041 ctgcttaggg aaaaatagtg tttctatgct agaaactaaa tcacacagct ttcacattgg
     2101 ttggcgccga cttctccacc gtcatctgta aaggtacgga cgtagtagat agacttgatt
     2161 cccttgttaa aggcatagtt acgaaggatg gacaagtcac gtgtcgtttg tttattttcc
     2221 ctcttccatt cgtaaaggcc ttttggaatg tcactacgca tgaagagggt gagtgaaagt
     2281 ccttgatcca cgtgttcagt cgcagcagcg taaacatcga tgactttacg catatccata
     2341 tcgtaggcag aagtgtagta aggaatggtt tctgtagaca agccagcagc agggtagtag
     2401 attttaccaa ttttcttttc ctgacgttct tcaatacgtt gcgtaatcgg gtggatagaa
     2461 gcagaaacat cgttgatgta gctgatagaa ccatttggcg ctacagcaag gcgattttgg
     2521 tggtaaagac catcctcttg aaccttgtcg cgaagttcag tccaatcagc aacaccaggg
     2581 ataaaaacat ttttgaagag ttctttaaca cggtctgatg ttggaacaaa ttcaccagtt
     2641 acatacttgt caaagtaact tccgttagca tagtctgatt tttcaaagtt gtggaaggta
     2701 ataccacgtt cacgcgcaat attgtttgac tctaccaagg tccagtagtt cataagcata
     2761 aagtagatgc ttgtaaattc aacagactca ggtgaaccat attcaatgag ttgttgggca
     2821 aggtagctgt gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct atttccatgg
     2881 tcaatcgttg gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag ggcacgaacc
     2941 atagcacgga tagaacgacc aaaatcaggt gaagtcatca tgttaaccac gttggttgaa
     3001 cccaggttac atgaaacatc tgttcccatt tgaaggaatt cttgagcatc gttgatcaag
     3061 cttggttctt gaacttgaag aatctcagaa cacaagttac tcatgataat ctttccatcg
     3121 acaggatttg cacggttagc cgtatcgatg ttgactacat aaggatagcc agactcttgt
     3181 tgcaatttag agatttcagt ttccaaatcc cgcgccttga tttttgtctt gcgaatattt
     3241 ggatttgcga ccaattcatc gtatttttca gtaatgtcga tgtaattgaa tggcacaccg
     3301 tattcttttt ctacagagta agggctgaag aggtacattt cttcattttt acgagccaat
     3361 tcgtagaatt tatcaggtac tacaacacca agtgatagag tcttgacacg tactttttca
     3421 tcagcgtttt ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa gacgttgagg
     3481 tagacaacgc cggcaccttg acgttgcccc aattggttgg agtaagagaa gctgtcttca
     3541 aaaagcttca taacaggaac gacacctgaa gcagctcctt catagccttt gataggtgca
     3601 ccagcttcac gaaggttgct gagggtaatt cccacaccac caccaatacg tgaaagttga
     3661 agagctgagt tgatagaacg tccgatagag ttcatatcat ccgtcacttg gattaggaaa
     3721 caagatacca actccccacg acgagcacgt ccagcattca agaaggaagg agtagcaggt
     3781 tggtagcgtt ggtggatgat ttcattggca atatcgattg caacagcttc attcccatca
     3841 gcgaaataaa gggcgttgaa gaagacacgg tcttccatat tttcaagata gtattcaccg
     3901 tcattagtct ttaaggcata ttgattgtaa aatttataag ctgccatgaa tgacttgaat
     3961 tggaagtttt ggtctttgat aaattgagcc aattcttcca agaactctgg acggtatttc
     4021 ttgataaagg ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt gtctttgatt
     4081 gaatcaaaaa ccatagtgtt tggaactaca ttttctttaa agaaagcatc caaggcttcc
     4141 tcatctttat gaagcatgat ttgtccatta acaggacggt taatttcgtt attaagacgg
     4201 aagtaagtca cgtcttcaag atgttttaat cccataaaat ttcccttatc taattacaaa
     4261 agaaaggctt ctaagttagc cctaaaagca gtttcttctg gatgatgtac taagattatg
     4321 ctaattgttt cagttttcct ggttggaaac ctgaaaagac ttcagttggt gtttggataa
     4381 caggagctgc gctaaaaccg agctctttaa cttgatcgac gtactcaggt tgctcatcaa
     4441 gattgatttc acgataagag acattattac tgtccaagaa acgcttggtc attttacatt
     4501 ggacacaatt gtttttagaa taaacggtta ccattgtgta actcctcttc aaaatttaat
     4561 actatcttag tatatcagaa aataaaattt tgtcaatgat ttaaactaaa tatagtggtg
     4621 ttcttttgtt gtttttatat ataaacacaa tatatagtgt ttgtgttgtg aaatagcaat
     4681 gattatccta taaattgttt ttgaagaaac tatatcctgt gttttgttat ctaggataga
     4741 agattttcag caagttatct gaaaggaaat tgaaggaaaa tccagaaaat gcttgaaaaa
     4801 aatcctagaa gatggtataa tactaaattg taagggttat cacatataac tcaaaaaaag
     4861 aaagaacaaa aggagagtca aactatggct tctaaagatt tccacgtagt ggcagaaaca
     4921 ggtattcacg cacgtccagc aacattgttg gtacaaactg ctagcaaatt tgcttcagat
     4981 atcactcttg agtacaaagg taaatcagtt aaccttaaat caattatggg tgttatgagt
     5041 cttggtgttg gccaaggtgc tgacgtaact atctcagctg aaggtgcaga tgcagatgac
     5101 gctatcgctg caatctcaga aacaatggaa aaagaaggat tggcataagg gaaatgacag
     5161 aaatgcttaa aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca tatctactcg
     5221 ttcagccgga tttgtcattt gagactatta cagtcgaaga tacaaacgca gaagaagctc
     5281 gccttgatgc cgctctacag gcatcacaag acgagctttc tgttattcgc gagaaagcag
     5341 taggtacgct cggtgaagaa gcagctcaag tttttgatgc tcacttaatg gttcttgctg
     5401 acccagaaat gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg aatgcagaag
     5461 caggtctgaa agaagttaca gatatgttta tcactatctt tgaaggcatg gaagacaacc
     5521 catacatgca agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta ttggcaaacc
     5581 ttcttggtaa aaaattgcca aacccagctt ctatcaatga agaagtgatt gtgattgcgc
     5641 atgacttgac accatctgat acagctcaat tggacaaaaa ctttgtaaaa gcttttgtaa
     5701 ccaacattgg tggacgtaca agccactcag ctatcatggc acgtacactt gaaattgctg
     5761 ctgtattagg tacaaataac atcactgaaa tcgttaaaga cggtgacatc cttgctgtta
     5821 acgggatcac tggagaagtg attatcaacc caacagatga acaagcggca gaatttaaag
     5881 cagctggtga agcctatgcg aaacaaaaag ctgaatgggc acttttgaaa gatgctcaaa
     5941 cagtgactgc tgacggtaaa cacttcgagt tggctgccaa tattggtact ccaaaagacg
     6001 ttgaaggtgt taacaacaac ggtgcagaag ctgttggact ttaccgtaca gagttcttgt
     6061 acatggattc tcaagacttc ccaactgaag atgagcagta tgaagcatac aaggctgttc
     6121 ttgaaggaat gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt ggagataagg
     6181 aacttcctta cttcgatatg cctcacgaaa tgaacccatt ccttggattc cgtgctcttc
     6241 gtatctctat ctctgagact ggagatgcta tgttccgcac acaaatccgt gctcttcttc
     6301 gtgcgtctgt tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc ttgaaagaat
     6361 tccgtgcagc gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct gaaggtgttg
     6421 cagttgcgga taacatccaa gttggtatca tgatcgagat tcctgcagcg gctatgcttg
     6481 cagaccaatt tgctaaagaa gttgacttct tctcaattgg tacaaacgac ttgatccaat
     6541 atacaatggc agcagaccgt atgaacgaac aagtttcata cctttaccaa ccatacaacc
     6601 catcaatcct acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa ggtaaatggg
     6661 ctggtatgtg tggtgagatg gctggtgacc aacaagctgt tccacttctt gtcggaatgg
     6721 gcttggatga gttctctatg tcagcaacat ctgtacttcg tacacgcagc ttgatgaaga
     6781 aactcgacac agctaagatg gaagagtacg caaaccgtgc ccttacagaa tgctcaacaa
     6841 tggaagaagt tcttgaactt caaaaagaat acgttaattt tgattaatcg aaaagtccct
     6901 gcaactcagt tacagggact ttttttgata ttttaaaaag aattttcaag aaaatctttc
     6961 ttataaaaag tccaaccttg aaaaagtagt ggtcagaaca aaaaatactt aaatggttca
     7021 taaaattctt gacaagttgg agatttagga gtaaactatt aaccagttaa gtaatagaga
     7081 ggagtttctg caatttagaa atgaattgca actagaaata tcaaatagaa agagagtttc
     7141 gatgaaaatt aataagaaat accttgttgg ttctgcggca gctttgattt taagtgtttg
     7201 ttcttacgag ttgggactgt atcaagctag aacggttaag gaaaataatc gtgtttccta
     7261 tatagatgga aaacaagcga cgcaaaaaac ggagaatttg actcctgatg aggttagcaa
     7321 gcgtgaagga atcaatgctg agcaaatcgt catcaagata acagaccaag gctatgtcac
     7381 ttcacatggc gaccactatc attattacaa tggtaaggtt ccttatgatg cgattttcag
     7441 tgaagaatta ctcatgaaag atccaaacta taagctaaaa gatgaggata ttgttaatga
     7501 ggtcaagggt ggatatgtta tcaaggtaga tggaaaatac tatgtttacc ttaaggatgc
     7561 tgcccacgcg gataacgtcc gtacaaaaga ggaaatcaat cgacaaaaac aagaacatag
     7621 tcaacatcgt gaaggtggga ctccaagaaa cgatggtgct gttgccttgg cacgttcgca
     7681 aggacgctat actacagatg atggttatat ctttaatgct tctgatatca tagaggatac
     7741 tggtgatgct tatatcgttc ctcatggaga tcattaccat tacattccta agaatgagtt
     7801 atcagctagc gagttggctg ctgcagaagc cttcctatct ggtcggggaa atctgtcaaa
     7861 ttcaagaacc tatcgccgac aaaatagcga taacacttca agaacaaact gggtaccttc
     7921 tgtaagcaat ccaggaacta caaatactaa cacaagcaac aacagcaaca ctaacagtca
     7981 agcaagtcaa agtaatgaca ttgatagtct cttgaaacag ctctacaaac tgcctttgag
     8041 tcaacgacat gtagaatctg atggccttgt tttcgaccca gcgcaaatca caagtcgaac
     8101 agctagaggt gttgcagtgc cacacggaga tcattaccac ttcatccctt actctcaaat
     8161 gtctgaattg gaagaacgaa tcgctcgtat tattcccctt cgttatcgtt caaaccattg
     8221 ggtaccagat tcaaggccag aacaaccaag tccacaaccg actccggaac ctagtccagg
     8281 cccgcaacct gcaccaaatc ttaaaataga ctcaaattct tctttggtta gtcagctggt
     8341 acgaaaagtt ggggaaggat atgtattcga agaaaagggc atctctcgtt atgtctttgc
     8401 gaaagattta ccatctgaaa ctgttaaaaa tcttgaaagt aagttatcaa aacaagagag
     8461 tgtttcacac actttaactg ctaaaaaaga aaatgttgct cctcgtgacc aagaatttta
     8521 tgataaagca tataatctgt taactgaggc tcataaagcc ttgtttgaaa ataagggtcg
     8581 taattctgat ttccaagcct tagacaaatt attagaacgc ttgaatgatg aatcgactaa
     8641 taaagaaaaa ttggtagatg atttattggc attcctagca ccaattaccc atccagagcg
     8701 acttggcaag ccaaattctc aaattgagta tactgaagac gaagttcgta ttgctcaatt
     8761 agctgataag tatacaacgt cagatggtta catttttgat gaacatgata taatcagtga
     8821 tgaaggagat gcatatgtaa cgcctcatat gggccatagt cactggattg gaaaagatag
     8881 cctttctgat aaggaaaaag ttgcagctca agcctatact aaagaaaaag gtatcctacc
     8941 tccatctcca gacgcagatg ttaaagcaaa tccaactgga gatagtgcag cagctattta
     9001 caatcgtgtg aaaggggaaa aacgaattcc actcgttcga cttccatata tggttgagca
     9061 tacagttgag gttaaaaacg gtaatttgat tattcctcat aaggatcatt accataatat
     9121 taaatttgct tggtttgatg atcacacata caaagctcca aatggctata ccttggaaga
     9181 tttgtttgcg acgattaagt actacgtaga acaccctgac gaacgtccac attctaatga
     9241 tggatggggc aatgccagtg agcatgtgtt aggcaagaaa gaccacagtg aagatccaaa
     9301 taagaacttc aaagcggatg aagagccagt agaggaaaca cctgctgagc cagaagtccc
     9361 tcaagtagag actgaaaaag tagaagccca actcaaagaa gcagaagttt tgcttgcaaa
     9421 agtaacggat tctagtctga aagccaatgc aacagaaact ctagctggtt tacgaaataa
     9481 tttgattctt caaattatgg ataacaatag tatcatggca gaagcagaaa aattacttgc
     9541 gttgttaaaa ggaagtaatc cttcatctgt aagtaaggaa aaaataaact aatgaaaaat
     9601 gaaagtctcg ataaagaggc tttcattttt attatgtata tatgtaaaat tcttgacaag
     9661 caatattaaa aagagtaaac tattaactag ttaattaacc ggtttattac tttatagtga
     9721 atcaaatata cttaagaaaa gaggaaagaa tgaaaatcaa taaaaaatat ctagcaggtt
     9781 cagtggcagt ccttgcccta agtgtttgtt cctatgagct tggacgttac caagctggtc
     9841 aggataagaa agagtctaat cgagttgctt atatagatgg tgatcaggct ggtcaaaagg
     9901 cagaaaactt gacaccagat gaagtcagta agagggaggg gatcaacgcc gaacaaattg
     9961 ttatcaagat tacggatcaa ggttatgtga cctctcatgg agaccattat cattactata
    10021 atggcaaggt tccttatgat gccatcatca gtgaagagct cctcatgaaa gatccgaatt
    10081 atcagttgaa ggattcagac attgtcaatg aaatcaaggg tggttatgtc attaaggtaa
    10141 acggtaaata ctatgtttac cttaaggatg cagctcatgc ggataatatt cggacaaaag
    10201 aagagattaa acgtcagaag caggaacgca gtcataatca taactcaaga gcagataatg
    10261 ctgttgctgc agccagagcc caaggacgtt atacaacgga tgatgggtat atcttcaatg
    10321 catctgatat cattgaggac acgggtgatg cttatatcgt tcctcacggc gaccattacc
    10381 attacattcc taagaatgag ttatcagcta gcgagttagc tgctgcagaa gcctattgga
    10441 atgggaagca gggatctcgt ccttcttcaa gttctagtta taatgcaaat ccagctcaac
    10501 caagattgtc agagaaccac aatctgactg tcactccaac ttatcatcaa aatcaagggg
    10561 aaaacatttc aagcctttta cgtgaattgt atgctaaacc cttatcagaa cgccatgtgg
    10621 aatctgatgg ccttattttc gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag
    10681 ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct
//
LOCUS       DAVLTG010000057        10711 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLTG010000057 DAVLTG010000000
VERSION     DAVLTG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.058"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            131..868
                     /locus_tag="VYN12_001747"
     CDS             131..868
                     /locus_tag="VYN12_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1416076.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            865..2556
                     /locus_tag="VYN12_001748"
     CDS             865..2556
                     /locus_tag="VYN12_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1416077.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            2672..3235
                     /locus_tag="VYN12_001749"
     CDS             2672..3235
                     /locus_tag="VYN12_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1416078.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            3257..8926
                     /locus_tag="VYN12_001750"
     CDS             3257..8926
                     /locus_tag="VYN12_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV1416079.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVMYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            8987..10708
                     /gene="pabB"
                     /locus_tag="VYN12_001751"
     CDS             8987..10708
                     /gene="pabB"
                     /locus_tag="VYN12_001751"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1416080.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
BASE COUNT         3541 a         1805 c         2391 g         2974 t
ORIGIN      
        1 gtactttgag aaacctgtgg ctatcttcct agtttacttt ttgattttta ttgagtataa
       61 gaggtctttc ctaagcagtt agaggagaat tttgctatac tgatactagt aagtggtaaa
      121 ggagcagagc atgacctaca caatcttaat cgtagaagat gaatatctgg taagacaagg
      181 tttgactaaa ctggtcaatg tagcagccta cgatatggaa atcatcggtc aggctgaaaa
      241 tggaaggcag gcttgggaat tgatccaaaa gcaggtgcca gatatcattt taaccgatat
      301 caacatgcct catctaaatg gcatccagtt ggccagtctg gtacgagaaa cctatcctca
      361 ggttcatttg gtctttttaa caggttacga tgattttgat tatgccttgt ctgctgtcaa
      421 actaggtgtg gacgactacc tgctcaaacc cttttctcgt caggatattg aggaaatgtt
      481 ggggaaaatc aaacaaaaac tagacaagga agagaaagaa gagcagttac aagatttatt
      541 gactaatagg tttgaaggaa acatggccca gaaaatccag tctcatctgg ctgatagcca
      601 atttagttta aagtctttag ccagtgactt aggttttagt ccgacctatc tgagttcctt
      661 gattaagaaa gagttgggct tgccttttca ggattatctg gtgagagaac gtgttaaaca
      721 agccaagctc ttgcttttaa ctacagatct gaagatttat gagatcgcag agaaggttgg
      781 ttttgaagat atgaactatt ttacccaacg ttttaagcag attgcaggtg tgacacctcg
      841 tcagtttaag aagggagaag accgatgaag cgttcttctc ttttagttag aatggttatt
      901 tccatctttc tggtctttct cattctccta gctctggttg gaactttcta ctatcaatca
      961 agttcttcag ccattgaggc caccattgag ggcaacagcc aaacgaccat cagccagact
     1021 agccacttta ttcagtctta tatcaaaaaa ctagaaacca cctcgactgg tttgacccag
     1081 cagacggatg ttctggccta tgctgagaat cccagtcaag acaaggtcga gggaatccga
     1141 gatttgtttt tgaccatctt gaagtcagat aaggacttga aaactgttgt gctggtgacc
     1201 aaatctggtc aggtcatttc tacagatgac agtgtgcaga tgaaaacttc ctctgatatg
     1261 atggctgagg attggtacca aaaggccatt catcagggag ctatgcctgt tttgactcca
     1321 gctcgtaaat cagatagtca gtgggtcatt tctgtcactc aagaacttgt tgatgcaaag
     1381 ggagccaatc ttggtgtgct tcgtttggat atttcttatg aaactctgga agcctatctc
     1441 aatcaactcc agttggggca gcagggcttt gccttcatta tcaatgaaaa ccatgaattt
     1501 gtctaccatc ctcaacacac agtttatagt tcgtctagca aaatggaggc tatgaaaccc
     1561 tacatcgata caggtcaggg ttatactcct ggtcacaaat cctacgtcag tcaagagaag
     1621 attgcaggaa ctgattggac ggtgcttggc gtgtcatcat tggaaaagtt agaccaggtt
     1681 cggagtcagc tcttgtggac cttgcttggg gccagtgtca catctcttct tgtctgtctc
     1741 tgcttagtgt ggttcagtct taaacgctgg attgctcctt tgaaggattt gagagaaacc
     1801 atgttggaaa ttgcttctgg tgctcaaaat cttcgtgcca aggaagttgg tgcctatgaa
     1861 ctgagagaag taactcgcca atttaatgct atgttggatc agattgatca gttgatggta
     1921 gctattcgta gccaggaaga aacgacccgt cagtaccaac ttcaagccct ttcgagccag
     1981 attaatccac atttcctcta taacactttg gacaccatca tctggatggc tgaatttcat
     2041 gatagtcagc gagtggtgca ggtgaccaag tccttggcaa cctatttccg cttggcgctc
     2101 aatcaaggca aggacttgat ttgtctctct gacgaaatca atcatgtccg ccagtatctc
     2161 tttatccaga aacaacgcta tggagataag ctggaatacg aaattaatga aaatgttgcc
     2221 tttgataatt tagtcttacc caagctggtc ctacaacccc ttgtagaaaa tgctctttac
     2281 catggcatta aggaaaagga aggtcagggc catattaaac tttctgtcca gaaacaggat
     2341 tcgggattgg tcatccgtat tgaggatgat ggcgttggct tccaagatgc tggtgatagt
     2401 agtcaaagtc aactcaaacg tgggggagtt ggtcttcaaa atgtcgatca acggctcaaa
     2461 cttcattttg gagccaatta ccatatgaag attgattcta gaccccaaaa agggacgaaa
     2521 gttgaaatat atataaatag aatagaaact agctaactcc cagtcaattc tgggagtttt
     2581 atgcgtaatt gggcaaactt tctaggttgt ctatcttgct aaaaacaaga aaaaacggta
     2641 tgatagaaga gtgacaacag aggtaacaga gatgaacgag acacagattc aaagagaaac
     2701 acgtcaggta gtggaagatg ttttagaaaa gaccaatttg aagcaggggg ccctttttgt
     2761 tttaggtcta tcttctagtg aggtgctagg tggtcatatt gggaaagaat ccagtcaaga
     2821 gattggtgag ctgatagtgg agactatctt ggatattcta ggtagtagag gtatccattt
     2881 agcagttcaa ggttgtgagc atgtcaatcg ggctctcgtt gttgaacgtc aggtggcaga
     2941 gcagtttggt ctggaaattg tcagtgtcca tcctactctt catgcaggag gttcggggca
     3001 gttggcagcc tttaagttta tgcaggatcc agttgaggtt gaatttatca aggctcatgc
     3061 tggattggat atcggagaca ctgcaattgg catgcatgtc aagcatgttc aggttccgat
     3121 tcgccctatt ttgagagaga ttggtcatgc ccatgtaacg gcactggcta gtcgtccaaa
     3181 attaatcgga ggtgcgcgtg cgcactatcc gcaagatgct attagaaaga cctgagaatg
     3241 aataaaggag ataaaagtgt ttaaaaaaga ccgtttttca attcgtaaga ttaagggagt
     3301 tgtaggctct gtatttcttg gaagcctttt gatggctcct tctgtagtgg acgcagccac
     3361 ctatcactat gtaaataaag agattatttc acaagaagct aaagatttaa ttcagacagg
     3421 aaagcctgac aggaatgaag ttgtatatgg tttggtgtat caaaaagatc agttgcctca
     3481 aacagggaca gaagcatctg ttttgacagc ttttggttat ctatcaggtg acatcctcaa
     3541 aacgcttggc ttggacactg ttttagaaga aacctcagca aaacctggag aggtgactgt
     3601 agtcgaagtt gagactcctc aatcaacaac aaatcaggag caagctagga cagaaaacca
     3661 agtagtagag acagaggaag ctccaaaaga agaagcacct aaaacagaag aaagtccaaa
     3721 ggaagaacca aaatcggaga taaaacctac tgacgacacc cttcctaaag tagaagaggg
     3781 gaaagaagat tcagcagaac cagctccagt tgaagaagta ggtggagaag ttgagtcaaa
     3841 accagaggaa aaagtagcag ttaagccaga aagtcaacca tcagacaaac caacagagga
     3901 accaaaagtt gaacaagtag gtgaaccagt cgagccaagt gaagacgaac aggcaccaac
     3961 ggcaccagtt gagccagaaa agcaaccaga agctcctgaa gaagagaagg ctgtagagga
     4021 aacaccgaaa ccagaagata aaataaaggg tattggtact aaagaaccag ttgataaaag
     4081 tgagttaaat aatcaaattg ataaagctag ttcagtttct cctactgatt attctacagc
     4141 aagttacaat gatcttggac ctgttttaga aactgcaaaa ggtgtctatg cttcagagcc
     4201 tgtaaaacag cctgaggtaa atagtgagac aaataaactt aaaacggcta ttgacgctct
     4261 aaacgttgat aaaactgaat taaacaatac gattgcagat gcaaaaacaa aggtaaaaga
     4321 acattacagt gatagaagtt ggcaaaacct ccaaactggg gttacagaag ctgaaaaagt
     4381 tgcagctaat acagatgcta aacaaagtga agtaaattct gagactgcaa gtcttaaaac
     4441 agcaatttct agattaaata cagataaagt tgaactcgaa aatcaactta agattgcaca
     4501 gggaaaaact gaaactgatt tcagcatgga atcttggact gttttgagta cagctaaaaa
     4561 taaagctcag gaagtaaaag ataacggaac agcgacccaa gaacaaataa acgaagcaga
     4621 gaaaagtttg aaaacagccc ttgctgactt atctgttgac aaaacagctt tgggaagcgc
     4681 tatcgataca gctactaaga aaaataaaga gaattataca aatcaaacat gggcagagtt
     4741 ggaaacagcg cttacagcag caaaatctgt aaatactaac gagtctaaac aaagcgacgt
     4801 taacgaagct gctgaaaaat taactgcaac tatggaaaaa ttggttgaat tgtctgaaaa
     4861 gccacgtttg actctatcta ttgaaaagag agacatagat cgaaaagcta cggtcacgta
     4921 tactttggaa aatccagcaa atactcaaat aaaatcaata actgcaactc tgaaaaaagg
     4981 agaggaagtt gttaaggatt ttgttttaac agaagaaaat cttaaaacta atcatttaac
     5041 tgctttgttt gaaaagctag actactacaa agaatacact ctatctacgg atatggtata
     5101 taacagagga aatgatgatg agacggagag tatttcagaa gaactaattc agctgaatct
     5161 taagaaacta gaattgaaag atatccagac agtctctctg atgaaatttg aaaatggtca
     5221 agaaagtcag gttacacact tgtctgataa accgaccgat ttgagtaaat tatacttaaa
     5281 agttacatca tcaacgtcta aggatgctgt gttagccgtt agctctatag aagaagagat
     5341 tattgaaaat aaaaaaatct ttaaaattca tgcagataca ccagaattag tagttcgtaa
     5401 gaaagatggc agtctttcta agggatttga ctattacatg gagagagtta tccctcatga
     5461 tggtgatatt tattatgatt ttaaagactt gatttcagct atgacatcta atcctacagg
     5521 tacgtttatt ttagggagag atatttcctc gcgtaatgta aaaccggatg gaaatggaaa
     5581 atcttatatc aaaggtgaat ttaaaggaaa actacttggt acaaatgata atgttagaca
     5641 ctcgatcttt gacttagaat atccattgtt tgatactata aaatcaggag tcgtgaaaga
     5701 tattgatttc aagcatgtca atatggtatt cccagatagc aatcaaggag ataacgtagc
     5761 aacaattgca agagtaatca aagataagac aaaaattgag aatgttaatg ttgaaggtta
     5821 tctcgagggt cgagatcatg tagctggttt agttaataat cttgaaggta attccgaaat
     5881 tgaaaatgta tcctttacag gaaagattaa gtctaaaggt ggtaattcta ttacagcagg
     5941 tattgcaggt agaaatatct tatctcgtgt taaacgtgcc tatgtaaatg cagatataga
     6001 ggtacatcga tcatctaatt ctagcatgct tgttgcagta aatggaataa acgcagatgc
     6061 aagtggtggt tggggaacct ggggtagact tactgagtca gttgctaaag gaacattaga
     6121 aaccaagcaa ggagggcaag ctggaggagc ctcttctaca gtctggcctt atggagcaat
     6181 tgataatgtt gtcagctatg caaaagtgac caaagggaaa gaattatttg gatcagatgg
     6241 tgatttaaat tatgattggt ttatgaaaaa aattagtaat atttttggtg ttcaaggcat
     6301 cagctcaggc gattcgggta gtgattctaa atttacgcgt atttctgagg aagaagcaaa
     6361 tcaaaaagtt gcttcttata atattacagc tcccaacttg atgagtgact caagtctttt
     6421 ggtagacaga ctcaatgaaa gttggaaaaa tactgatcaa tttgaaagta tacaggatta
     6481 tcaagcccaa aaccaattaa tttaccagaa cttgactaaa tttactcctt attacaataa
     6541 agaatttatt gttcatgaag gaaatgctct cactcctgaa caggaaatat tgaagactaa
     6601 gaaaatcaaa tcgattgtag ggttgaaagg aacagagttc gttgtagatg gcagtgatat
     6661 tgatactatc atgcttcatt ttgaggatgg tagtcagaag cgatataagg taacctctac
     6721 tggtaagttt tcgataacta atttaccgga atatcaggtt gaagatttaa atgtgatgta
     6781 tacatcagaa catatagtac atccactaga ttcgtcactg ataaataacc ttgttgaaga
     6841 attgaaaaaa gtagaattgt atacagagtc tacttaccaa gttctaggta ttgataaaga
     6901 taatgctaac aaattgaata gaactaagag attattctta gatgagtcat tagatgctgt
     6961 taaaacacaa ttgcctacct ttgtaaaaac aatgtttgaa aatgagtggt tgcacatcaa
     7021 tggagaatct agtggagctg tcgctgcttt acgacaaaaa atcatggata ataagacggc
     7081 tatattgctt gctttgactt atatcaatcg ttattatgat gttaaattct cagactataa
     7141 tattaaaaaa ctgatgctct ttaaaccaac tttccatggt gaaaagattg atctattaga
     7201 tcgattaatc cgactaggat catctggaga aaatagatta aaaggttcag aaaatgcaga
     7261 aacgttcaag cagttatttg ctagcgaaac gaagcagaag gatttggtga cttatttaga
     7321 ctacaatcgc tctttgttga ctaattatca aacaacaggg gaatggttta aagaaacgac
     7381 taaggattat attcaatttg aggaacgtcc atccttagta gaggagatta aagatgccaa
     7441 atatcgagtt tacgataatt taaccgcacc gtattatcaa ggatatatcc tacctctctt
     7501 aacgttgaag aatactcatt tagcaatttt atcgaactat agtactatga catttgtcag
     7561 ccgtgaaaaa cgccctaatt ggaaaaatga agattttgat aagtgggtga aatatgtagc
     7621 aactgctcat agaaaccatg ttgatacttg gtataagatt ttacctgata atatcaaagg
     7681 taaaatggtt aaagagaatg ttactgctgt ttgggaagga ttgagcatcc caggaagtga
     7741 atgggtagac cagaatgctg tagatagaaa aggaagagat tacgccccag ctcgagaatt
     7801 ctttaatctt gtaggtggtc ctatgggagg ttggtatgct taccatggtt atggtgcgca
     7861 tgctggagga agaaatcggg ttaattatga ggtgtttgat gtattaagtg agtatggtat
     7921 atcggtcttt actcatgaat tgactcacgt taatgatact tggatttact taggagggta
     7981 tggtagacgt gaaaatatgg gacctgaagc ttatgctcag ggattattcc agtctcctgt
     8041 tccaggtcag ccgggttggg gggcgcttgg tctcaatatg gcatttgaaa gaaaaaatga
     8101 tggtgatcta atttataatg cctccccaac tcaatttgaa aataggaaag agttagatag
     8161 ttatatgaaa aattataacg atactctcat gatggtggac tacttggaag gagatgcagt
     8221 tatctctaaa ggtaaagaag ctattactaa atggtttaaa aaagttgaac ctaaggttgt
     8281 tagtcaaaca gctcagtatg atacggttcg tcagttgact gctgaagaga aagaaaaact
     8341 ttctgtttct agtgttgatg atttagttga tcaaggatta atgtcagaca gagctgtagg
     8401 aaataatacc tataatccag ctgattttga aacaagttat attgcgatag attatatgac
     8461 tggtatttat ggtggaggaa agaatagtgt aggttcacca ggtgccttga tgtttaaaca
     8521 taatactttc cgtatgtggg gctactatgg ttttgaagaa ggtgttctag gatatgcttc
     8581 taataaattt aagcaagcat ctagagatga aggtcatgct ggacttagtg ataactttat
     8641 tatttctaag atttccaaag gggaattttt aactatggaa gcatttaaaa agggatattt
     8701 taagaaagta gtagaagagt taaaaactaa aggtattcgt cctgttacta tcaatcaaaa
     8761 aacatatagc acctttgaag aattgcaaga aggatttaag caggctgttg aaagagattt
     8821 gaagaaaaat cagttagatg agagggaaac aagaaacttc aaattccaag ttttcagaca
     8881 acttcttcaa caaacagata gctttaaaac ttctatcttt agataatcga aatctctcat
     8941 ctgctttgcg gatgagggtt ttcttatttt atgctatact taaagtatgc atagaaaaac
     9001 agtgattgat tttaggactt tgggggagag atataccttt acccagccta ttaaagagtt
     9061 gaaaacgaga aatgtagaag aagtggcaga tttgctggca caagtggaaa gctaccaaga
     9121 gcaaggttat tatgtggtgg ggtatgtcag ctacgaggct gcacctgctt ttgaggaaaa
     9181 attagcagtt cacaaggatc ccctactggg agagtacctg ctttatttta ctgttcatga
     9241 tagcgtagaa acttccccta ttcctctgac ttatgaggat attgatttgc cctcaaattg
     9301 gcaggaagta acgtctgcag cagactatga aaaggccatt gcccaaattc accatcattt
     9361 acggcaggga gatacctatc aggtcaacta caccgtccaa cttaagcaaa agttaaatgc
     9421 caatcctttt gccatctaca atcgtatggt ggtagagcag gaggcgggct acaatgccta
     9481 tgtggaacat gacgagatgg cagtgatttc catgagccca gagctctttt ttgagcaaaa
     9541 tgatcgcgag ttgacaacac gaccaatgaa ggggacgact cagcgtgggg taactgacca
     9601 agaagatctt gaacaggcca gttggttgga acaggatccc aaaaatcgct ctgaaaatat
     9661 gatgattgtg gacctcttgc gcaatgatat gaaccgtatt tctgaagttg ggagcgagca
     9721 cgtggagcgt ctgtgtcagg tagagcagta ttcaactgtt tggcagatga cttcgaccat
     9781 caagagtcag ttgcgagagg atgtggacct tgttgaaatc ttccactcac tctttccttg
     9841 tggttccata acgggtgcac cgaaaattgc gacaatggag attatcaagg acttggagcc
     9901 tcaaccgcgt ggagtctact gtggaacgat tggtctcttg cttccaaatg gacgacggat
     9961 ttttaatgtg gccattcgta ccattcaact tcacaaaggt caagccattt atggagttgg
    10021 cggagggatt acttgggata gcacttggga atctgaatac cgtgaagttc atcaaaaggc
    10081 agcagttctc tatcgtaaac aagctcgctt ccaattaatt acaactggaa aaatcagcca
    10141 aaaacaactg atgtttgaag aacaacatct ggaaaggctg agaaaagcta gtcggtattt
    10201 tgcttatcct tttgacccag aaattttgag acaaaagatt gaagcagagt gtcagacttg
    10261 tgatgctaat caagattacc gcttgcgaat ttctctcagc aagtctggag agatagaatt
    10321 cagtcgtcaa atcttaacac ctcttagtcc aagtttttgt caggccaaac tttgtctgca
    10381 agaagcgaat ttgaatcaat cctttaccta ttttaaaacg acttacagac cgcatttgag
    10441 catagaggaa caagagaaga tttaccataa tggaaaagga gaacttcttg aaacctctat
    10501 cggaaatttg gttctgaaaa tcgatgggaa actctacaca ccgcctatcc gacttggaat
    10561 cttgccagga atttatcacc agtatttact agaaacagga caggtagaag agaaagtctt
    10621 gaccttggca gattttgccc aagcagaagc tatttacggc tgtaatgcag tgagaggctt
    10681 gtatgagttg caagtgatag gattgtgagt t
//
LOCUS       DAVLTG010000058        10664 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLTG010000058 DAVLTG010000000
VERSION     DAVLTG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.059"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(19..1443)
                     /locus_tag="VYN12_001752"
     CDS             complement(19..1443)
                     /locus_tag="VYN12_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1416081.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHTAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(1988..4267)
                     /gene="pulA"
                     /locus_tag="VYN12_001753"
     CDS             complement(1988..4267)
                     /gene="pulA"
                     /locus_tag="VYN12_001753"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1416082.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4393..6351)
                     /gene="ligA"
                     /locus_tag="VYN12_001754"
     CDS             complement(4393..6351)
                     /gene="ligA"
                     /locus_tag="VYN12_001754"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1416083.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6444..7622)
                     /locus_tag="VYN12_001755"
     CDS             complement(6444..7622)
                     /locus_tag="VYN12_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1416084.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7702..8565)
                     /locus_tag="VYN12_001756"
     CDS             complement(7702..8565)
                     /locus_tag="VYN12_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1416085.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8568..10469)
                     /locus_tag="VYN12_001757"
     CDS             complement(8568..10469)
                     /locus_tag="VYN12_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1416086.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3195 a         2352 c         1900 g         3217 t
ORIGIN      
        1 atttcctggt tttacacgtt atttcacatc aaaaacaatg gatttgacat ttgtcatcgc
       61 ttcaatgcta tatttaattc cttgcactcc agctccagaa cctttgacac caaggaatgg
      121 gaaattatct ggaccacgct gggttttatt attaatgtgg actgtaccta cttcaagttt
      181 ttcagcaatt tcaaaggctt ttttgaaatc atttgtaaag actgatgatt gaaggccgaa
      241 ttcagattcg ttggcaaagg caatagcttc ctctacacta gccacacgaa tgattggtaa
      301 aacaggacca aatggctctt cccatgccac tttcatatct tttgtaactt ggtcaaaaag
      361 cactggccag agaagattgc cctcacgttt gattggtgta agagcctgag cttctttttc
      421 ttgtgcatcc tcaatcaagc cccaaatgaa gtcggctgaa gcattgtcaa taacaggtgt
      481 aatatcagca ttgtcaaatg gatcaccaac tgttaattta gaaacttctt cctgaagcaa
      541 agtagctaat ttatctgcta cactttcgag aacaatgaca cgtttaatgg ccgtgcaacg
      601 ttgtcctgag tagctaaagg ctcccgcaac aatttgcttg gcagtatgtt ccaaatctgc
      661 atcttctagt acaagagctg catctttccc accaagttcc aacatgatag gacgcatacc
      721 agctaaacga ccaatacgtt ctccaatagg agttgaacct gtaaagttga tgaagttgac
      781 ttctttgtgc tcaatgatat aatccccaat ttctgaacca cgacctgtaa tggtgttgaa
      841 aacacctgcc ggaatccctg cttcttcaaa tgctttagcc aacaagagtc cagaaatgga
      901 accttgtgtt ggtggcttaa acatgaccac attccctgca atcaaggcag gtgcaatttt
      961 agaagcagat aaattaactg gataattaaa gggagcaatc gctagcacga taccaactgg
     1021 ttcacgacgg acaacagcca gtttgttttt acttgctgcc tcaaaaccac caccttccat
     1081 tgcttgtcca gtgatacgga gaccttcctc agcagcataa cgaatcaagt ctgctgtacg
     1141 cactacttct ccaattgctg ctttaatccc ttttgctact tctttggcaa ggatagtacc
     1201 aatttcttcc ttatcgcgtt ctaaaatagc tgctgtttta tgtaaataag ccgcacgttc
     1261 aactgctgat aaagctcgcc atgctggcag ggctgcacgc gcagcttgca tagcctcatc
     1321 agcttcagtc tgagtcatgg ctggaactgt acccaattct tcttgattga ttggtgaata
     1381 aatcgtaatt tcttgttcag atgatttcca ttttccattt actaaattct gatatcttgt
     1441 caaattcttg tcctcctgaa aatgattaag atatatttta ccaaattttc agaaaatcac
     1501 aacccttttt gcaaaatttt tgagattatt ttcacaaact tgatttttca aagtatactc
     1561 aataaaaata aaaaaaatcc actacgtcaa ggcgaggcta atgtggtttg aagaaatttt
     1621 cgaagagcgt gaatgagtat catctatagt aaaataaaaa aactgaacaa tttggttggg
     1681 gacagccaaa ccaatttctc acaatgtttc agaaacaagg gtgtgctact ccaatttcag
     1741 cctactataa ctgtcataga ttgctgaaac aaagtctagg taaaagtctt cataataaaa
     1801 agacctccta tcaagtgttc aaaaactttg ataggaggtc ttgttttgtg aaaatattta
     1861 tcaaattttc tatacaagtg agctgttagc caggttcttt ctattctttc aatttcaatg
     1921 aatggatttt ttactaatac tcataactgg gaatttgtct gtgtaaaaat agcgagatag
     1981 atggtattta taaaacactc aagacagcta gactaatatc atttaaaaca ttatcttctt
     2041 ttgagcgact gttggttacc aacatagcta aatttcctgc attttcaaat tgatagggtt
     2101 ctgatttagc attcacaacc accaagaggt gttctttgcc gtgaacttca tagataaggt
     2161 agccgctatg ttcaatcgca gaatgcacaa agacatgatg gtaaatttca tcatagctag
     2221 agtaagaaaa ggcaccagtt tttgtcttca atcggatgac ttgacggata aactcaatac
     2281 tgtcttgacg ctcattaatc aagttccagt tcacttggtt cacactgtca ggagcattat
     2341 agctattcat cgcacgctct ctatcatcat gggtcaactc accattttca ccagtcgcaa
     2401 ccagtttggt acgaccaaat tcttgaccga tttccataaa ggccatcccc tgcatgagca
     2461 gattcatggc tgtggcagtt tcgaccttgc gcatgatttg ctctgaactt tggtctggat
     2521 gaagggttgc caataaatcg tgaagattgt aattgtcatg ggcttctaca tagttaagca
     2581 cctgatttgg atgtgtatag cttcctaatt cacgacttcc taggattgct ttagctagaa
     2641 ttggctctgt cgcagcacca ctgacaaaac ctgacttgat agcaccataa acttctcccc
     2701 ctttgacagc atcgcgctga ttgtcattaa agaaaccaat atttggcatc tggtaggcat
     2761 tgtccttctt ggccttatca taaggggcaa gacctgttcc catatcccat ccttctccat
     2821 agaggataat gttggagtcg atttcatcca agctttgacg aatcatctgc atggtcttga
     2881 catcatgaat ccccatcaag tcaaaacgga agccgtcaat attatattcc tgcacccagt
     2941 atagaagaga atcaatcata tacttgcgaa acatttcgtg ttcactggct gtttcatttc
     3001 caacacccgt tccattctgg aaggtaccat ctggattcat acgataatag taatcaggga
     3061 ctgttgtttg gaatggtgca tcaacaactg agaaggtatg gttatagact acatccataa
     3121 tgactccaat acccgcatcg tgataagctt gaaccatcac cttcaaatca cgaatgacct
     3181 gagctggatc atctggatta gttgaaaaac tagtttctgg cgcgttatag ttttgtggat
     3241 cataacccca gttgtaggtt acatttccat cctcatcgta ttctttatga cggtctgcaa
     3301 ttggttgcaa ttgaacataa ttgtagccca gcttcttgat gtaatcaaaa gcagttgact
     3361 ggccgtattg gttaactgtt ccagcctgag cagcacccaa gaaagttcct cgaagatgtt
     3421 catctacacc cgatgtaggt gatttagtca aatcacgaat atgcatttca cagataactg
     3481 ccttacatgg attttccaag cgccaagtag cctccgaacc gtgcttaacc tcgaagtttt
     3541 caacttgctt ttctacatgg ctcagaatag ctgaacgttt gccatcaggg ctggtcgcga
     3601 ttgtataagg atcacgtgtc agtgtttggt gatgagggaa ttggacttga tactgataag
     3661 ccttacctac caaatcttcc tcaacatcca aactccagac accgattgta ttgtccttat
     3721 gattataaga gtagctattg cctcttttca tctcaaaagt cttccaaacg ggtgcatcat
     3781 tagcagctga ttcataaacg acaacttgca cttctgtcgc tgtaggtgac cagagggaaa
     3841 aatgagcctg attgtcctct acacggcaac ccaattctcc ttggtaaccc caatgatggt
     3901 caaaactagc actgttaatg gccttatcaa aggcaaaagg attttgattt ttatagaaag
     3961 gactggcaat agcaggattt tcagagtaat aaatcctatc atcgccttcc aaaatccaga
     4021 cctctgttaa taggggatag tgattaaaac ggatagaata ttctttacta gtttgacctg
     4081 tatgaaccac aaaattcaag ctttctataa catgtgaact tgggtgttca aagctaaata
     4141 aagctccaaa ataatcttct ttgtaggtta gcaaatcaat tcgttgatcc tgacttttta
     4201 caaaggagca agtgtcatat tctccattct tacgatggta atgaatgcgc atagggtagt
     4261 tatacatttt ttatttttta ttttttattt ttccttttta ctttgtttct atttcactaa
     4321 taaatttttg tcaatctcgt ctcaattaac agacatagtc atattctcta aactctgttt
     4381 ttaaacgatc cattacaaac tttctagcca tgcctcatct ctgacctgga taccaagttc
     4441 ttgtgctttt tgcagtttac ttccagcgtc tgcacctacc acgacgaggt cggtcttttt
     4501 agaaatacta cctgtcactt tggcacccag actttcgagt ttacttttag cttctgagcg
     4561 cttgagtcgt tccaattttc ctgtcaatac cacggtcaaa cctgacaagg ccgcatccgc
     4621 tactaccgtc tgtcctttat agtccagatt gaccccagtt tctttcaatt ctctgagcag
     4681 aatttcagag ccttctgtcg caaaataagt ctgaagactt ttggcaatca cgccacctag
     4741 actttcaata ctagccactt cctctgaatc tgcctgagac agattttcaa ttgaatggaa
     4801 atattgaagt aaaagctgac taaccttgct tccgacatga cgaattccca aaccaaataa
     4861 gagcttctcg gcagaatttt cctttgatgc ttggatagcc tgatacagtt tagcagcgga
     4921 cttttcctta accccctcta aaaggaggaa atcctcttct tgcaaacgat aaatatccgc
     4981 cacatccttg actaaattag cagcaaaaag cttctcaaca atagatggac caaggcctgt
     5041 aatattcata gcatcacgag aagcaaagtg aatcaagcct tccatgattt gagcagggca
     5101 acgcggattg atacaacgta gggccacttc atcttcaaag tgcaacaagt cagagttaca
     5161 acttggacag tttgtaggga tatctagttt ttcttcagaa acccgtttgg actctaccac
     5221 acgtaaaacg gcagggatga tgtcaccagc cttatataca atgaccgtat cgtcttttcg
     5281 gatatctttt tcagcaatat aatctacatt gtgcagggtc gcacggctaa cagtcgtacc
     5341 ggcaagttgt actggtgtta gattagcagt tggagttaca acaccggtac ggccaactgt
     5401 ccagtcaact gataagagtt gagcttcttt ttcttcggca gggaacttgt aggctactgc
     5461 ccactttgga gccttaactg taaaaccaag ttcttcttga cttgctaggt cgttgacctt
     5521 gattaccact ccatcaatat cgtaaggcag attttcccgt tcctgtccta cttcttggat
     5581 aaaattccag atttcatcta tgttttcagc caagattcgc ttaggattga ccacaaaacc
     5641 tagttgttct aggtacttca aacccttttc ttggctatca cgagttgaag ggctggcttc
     5701 ttgatagaga aacgttgcaa gattacgctt ggcaactact gctgtatcca actgacgcag
     5761 agttcctgct gccgcattac gaggattagc aaattcaggc tctccatttt cttggcgcac
     5821 ttggttaact tggtcaaagg aagcgcgtgg catgtaacat tccccacgaa ctgtgatatc
     5881 tagttcttct ggcaaagtca aagggatgtc cttaacacgc ttgaggtttt ctgtgatatt
     5941 ttcaccaatt gaaccatctc cacgtgttac cccagcaacc aaaatcccct tttcataagt
     6001 cagcgagata gataagccat cgattttcag ctcacaaata taggtcggat gagccacttc
     6061 cttacgaaca cgcgcatcaa aagcatctag ctcctcacgt gaaaaagcat cctgcaaact
     6121 ataaagagga tactgatgac tgtatttttc aaaaccatct aaaaccttgc caccaacacg
     6181 atgagtcgga ctgtctgcta gcacttgctc tggataagca gtttctaact cgaccaactc
     6241 acggtaaagg cggtcatact cactgtctgc aaccgaggga ttatcgctgg tatagtactc
     6301 agtcgcatag cgattgagca aagcgactaa ctcattcatt cttttattca taagaccatt
     6361 ttaccataaa acaagccctc ctcacaaacg agaagggcgg aaaaaacact tagtttgaaa
     6421 ttatttttga aactcaagca accttatatc aatttttcaa aatgagttcg aacataaata
     6481 aacgatatac aagacaagat gataacacca cttccaatta tcaggaaaga agagagatgt
     6541 acacttggca agactgtcat aaatcctttt gcaataggca taaatagaat agctaaggta
     6601 aaaattgtac tcagtactct tccaagaaat tcgctctcaa ccttggtttg tacttgagta
     6661 aaaaagtgaa tattaaaaat cgtcataaac aattcacaaa ctaaatttcc agaaaaggaa
     6721 agaaaagttg gaagtggtaa tcccatcata aaaactccga cacctgtcaa agccagtaaa
     6781 atcaaaagat tataaatatt agctttaatt ttactagcta gaagagcccc aatgatggaa
     6841 ccaatagccc ccatagttaa aatacttgca taggctcctt ctgacccgta aagctgattc
     6901 gaaaagggaa gtagaaattc aaaagctgca aaaaagaaat taacgctgga agctaccagc
     6961 aaaaggaaga aaatttcttg ctgatgccag atatagtgta acccatcctt gatatctaca
     7021 aaaatatctc tcccagtaaa agcctttttc tcttgaactt ttgcttcctc ttttggaagg
     7081 aaagccacta gaacaaaagc aatgaaaaaa gtcagcgagt ctagcagtag cgtcatattg
     7141 agacttgcaa actgtaaaac aaggaaggaa agaacaggag agctaacacc tacaacctgc
     7201 aaaaccagct ctaagcgaga attatagatc acaatctcat ctttctccac cacttcagtt
     7261 atgatagctt tattggctgt gcgagaaaag gcaaaagcaa tagcctgcac aatgttagca
     7321 acaatcaaag cgccaatcat ccagctatca ttccttatga aagaaatagc cagacaaaga
     7381 atcccacaaa caagatctgc cgtcattaaa atcttacgac gagaaaaacg gtctgaaata
     7441 actccgccaa agggattgac gagaatagat gtgacgagct cagaaatctg atacattcct
     7501 aaaactgtct gtcctatagt ccccatagaa gccaaccaga cactatttcc ataatcatag
     7561 agcatatttc ccattttatt gatagcccca cggctaatca actgcactgc atagcgattc
     7621 atattaaagc tcctctcaaa ttttgaaact attgtatcaa aaccgaaagg agctttttat
     7681 tttttccctt atttgggaaa attaactttt gacaaatttt tcgtagtgtt cctgataata
     7741 ggctacttgc tctggaagac ctaacacatc aaaaatatgc atggcctttt gcatctgctt
     7801 acagccttct ttacactgtc ctttttgata taaggcaaaa ccttttaaat aatggaaaac
     7861 attacgctca taaagcttaa tacctttgtc aataatcttc tctgtataag cctcaaaata
     7921 gttggcatta taaaaagaag aatgctctaa acaatgctgg taacaattga gggccaaaat
     7981 caaaactaat ctcttatggc gactaatctc ttggtaaaat tcctccctct ccataacttc
     8041 tctaccaatc cgagtgacat agtctacatc gtagaaacta tagaggttac cgaaaagaat
     8101 caactcatac atggtccatt cttctgtttt gaagagataa tctgctacct tatccaaatc
     8161 atcctgcttc atatcataag tcgcatctct ttgacaaatc agaccttgta gcaaaatcca
     8221 gttcagctca aaataaaggg aagtcgtcga actcttagac ttttcaagtt gttctctttg
     8281 aagcttttga aaacctgcaa tatcgtttga atagtaaagt gggataatct gtgccatcat
     8341 agacacatgt tcatgattat gaaaattcct tgccttatcc atgaaatttt cgattgttac
     8401 atgaatgtta tccaaaatct caaagaaacg ggagactgcc aggtcagact ccccaagctc
     8461 aaagcgagat aactgagagg tagagcagga ttcgcctgct gcttccttta aagaataatt
     8521 tccacttgtt cgaaattcac gaaatacttt tccaagatgt tccatcttta cacctgatct
     8581 gataattctt cccactcaag catagcttct tcctgacgat ggctgatttt gtccagctca
     8641 gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca acatttgttc agaaatggct
     8701 tggctttgac tttctagctc ttcaatttca gcttctagac tttcgatttg tcgcatgagt
     8761 ttgcgaactt ctttttgact ttctttctgg gcctgatagt cattgactgg acttgcttcc
     8821 tttgcttgat tgctagttga agcttcctca gtctgactca tttctgctgt tgctttcttc
     8881 tcaacatagt agtcgtaatc tccaaggtag agagttgaac cattctcaga caattccaaa
     8941 acatgagttg ccacacgatt gataaagtaa cgatcatgac tgacaaaaag caaggtacca
     9001 tcaaagtcaa tcaaggcatt ttctagcact tccttactat caatatccaa gtggttggtc
     9061 ggctcatcca gaatcaaaaa gttattgttt tccatagaca atttagctaa aagcaaacga
     9121 gctttttcgc caccagatag catgccgact gattttttaa catcatctcc tgagaaaagg
     9181 aaggccccaa gacggttgcg gatttcaact tctggtgtca gtttgaaatc attccagagt
     9241 tcatccagca ccgtattact tggtgtcagc ttgctttggg tttggtcata gtaaccaacc
     9301 tcaacattag cgccaaagcg cttttcacct ttgataaaag gaatctggtc cacaatagac
     9361 ttgataaagg ttgacttgcc gataccattt ggaccaacga tagcgacagc attcatctta
     9421 cgaagatcta ggttgatagg ttgtgacaaa acttccccgt cataaccaat agcagtattt
     9481 tcaacagtca aaacaacatt gcccgacgtt ttttcagact ggaaggtcat gttggctgct
     9541 ttcttgccag cttcaggctt gtccaaacgc tccatttttt ctagttgttt acggcgagat
     9601 tgagcacgtt tggtcgttga agcacgaact agattgcgat tgacaaagtc ttccagagca
     9661 gcgatttcct tctgttgctt ttcatagttt tttgcctcag tagctagctt ttgctccttc
     9721 aactcaacaa aacgagagta attccccaca tagcgatcca aggaatactt ggtcaaatct
     9781 agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt ggctgacgat aatgagggca
     9841 ccgctatagt ttaccaagta attctctagc caggagatgg tttcaatatc caagtggtta
     9901 gttggctcgt ccaagaccaa gagattgggc ttttcaagga gcattttagc tagagccaaa
     9961 cgagtatttt gaccaccaga aagctcagca attttcatct gccacataga ctcgtcaaac
    10021 ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg taaagccacc tgcttggcga
    10081 aaattttcag ataagcggtc ataatctgac atcagtttat ccaaatcctc accagacttt
    10141 tcacccatct ccagctccat ctgacgcagt tgtttatctg tccgacgtaa gtcatcaaag
    10201 acatgaagca tctcatcata gatggtattt tcagactcaa aacggctatc ttgagctagg
    10261 taagacagag aaatatcttt tttcttattg atttctccac tagttggctc ctcttctcca
    10321 actaaaatct tcaaaagagt agacttacct gcaccatttt tcccaacaag ggcaatccga
    10381 tctcgttcat caacctgcag gttgatatta tcgaaaagaa cctctcctgc aaaagaacgt
    10441 tcaattttat tagcttgtaa aataatcata caagtagtat agcatgtttc cctaaggcat
    10501 tcaagataat cgtaagtctt ttagtacaac ttttataaca taaaataaac taaattatgt
    10561 atattttata ttagattcct tcactatctt gttggatttt ctaaccagct aatcttgttt
    10621 caaatagtta tcgcacaagc ctattattta attcttttca ttat
//
LOCUS       DAVLTG010000059        10520 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLTG010000059 DAVLTG010000000
VERSION     DAVLTG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.060"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..1716
                     /locus_tag="VYN12_001758"
     CDS             <1..1716
                     /locus_tag="VYN12_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1416087.1"
                     /translation="LEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAG
                     SPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAG
                     TDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKD
                     TYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEM
                     THNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQ
                     VADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPD
                     PDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFS
                     PIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYG
                     KQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQK
                     VTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSI
                     FENKK"
     gene            1760..6973
                     /locus_tag="VYN12_001759"
     CDS             1760..6973
                     /locus_tag="VYN12_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1416088.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNMDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            7245..8096
                     /gene="ylqF"
                     /locus_tag="VYN12_001760"
     CDS             7245..8096
                     /gene="ylqF"
                     /locus_tag="VYN12_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1416089.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8083..8862
                     /locus_tag="VYN12_001761"
     CDS             8083..8862
                     /locus_tag="VYN12_001761"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1416090.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            8878..10428
                     /locus_tag="VYN12_001762"
     CDS             8878..10428
                     /locus_tag="VYN12_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1416091.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNILITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3603 a         1731 c         2150 g         3036 t
ORIGIN      
        1 ttagagaaat atagaaaagc atttgtacca gataaaacaa ataatgagtg gtttaaagaa
       61 caaactaaag catatattgt agaagaaaaa tctactatta aagaggtaag tgataagcaa
      121 tcaatagctg gtagtccata ttcaattgga gtatatgata gattaactag cccatcttgg
      181 aaatatccaa gtatggtgtt gccgctatta acattacctg aaaaatcggt gtttattata
      241 gccaacattt cgactatagg tttcggtgct tatgatagat atagaagtaa agaacatcca
      301 gcaggaactg atttaaatga ctatgttgag aaaaaagcta aagaagcggc tgttagattt
      361 agagatcact atgattattg gtatagaata ctagatgata aaaataaaga aaaattatat
      421 agaagtgttc tagtctatga tgcatttaga tttggtacag atgaaaaaga agataaagat
      481 acatatcaag caacttttga aactaatcat ccagctataa aacatttctt cggtccagcg
      541 ggaaataatg ttgttcataa ttctaatgga gcatatgcta caggggatgc attctattat
      601 atggcatatc gcatgcttga taaagatggt gcggtaactt atacacacga aatgacacat
      661 aactcagata gagaaattta tcttggaggc tatggaagac gaaatggact tggaccagag
      721 ttttatgcta aaggactgct acaagctcct gatcatccta atgatccaac agtcactatt
      781 aattccatat taaaatatga tcaatcagaa gaatcaacaa ggcttcaagt agcagatcca
      841 actcaacgat ttggaagtgt tgatgatcta aataagtata tgcataatat gtttgatgta
      901 atatacatgc ttgaaatact agaaggtaaa gctgtagcta aattagatac aaatcaaaaa
      961 tatgatttat taagaaaaat agaaaatgaa tataaacctg atcctgatgg aaattctgtt
     1021 tatgcaacga atgttgtacg tagattaaaa ccagaagaac ttactaaatt aactacattt
     1081 aacagtttga tagaacatga tattataaca agaagaggtt atgtagatga agcaacttat
     1141 aagcggaatg gctactatac aattaatcta ttctcaccaa tttattcagc attgagcagt
     1201 aaaataggaa caccaggaga tttaatggga cgacgtattg catttgagtt attggcagcc
     1261 aaggggtaca aagacggtat ggttccatat atttctaatc agtatgaaaa agaagcgaaa
     1321 gctcaaggaa aagttattac atcatatggt aaacaaatag gtttagttac tgatgaaatt
     1381 gttctttcaa aagtatttaa taaccagtat aattcttgga tagatttcaa gaaagatatg
     1441 tataaagaaa gagaagataa atttggaaag ttaaataaag ttagttttat cgatccaaac
     1501 ggttcttggg ctcgacaaca gaaagtgact attgataata ttaatagact tgaaaaaatg
     1561 attgaagatg cagtaaaatt tgatgctgag gatgaagttg ccaaattata tcctgagaca
     1621 aatagtagag ttcttaaact gaaaaaagca atctttaaag cttatcttga ccaaaccggt
     1681 gattttagaa gttcaatttt tgagaataaa aaatagtgtt tactattagg aaataaaaag
     1741 tgaaggtgga ggattagaat tgtcattatt aaaaaaagat aaattttcca ttcggaaaat
     1801 aaagggtatt gttggttcgg tattcttggg gagtctttta tttgcaccgt cagttgttgg
     1861 tgcatcgact tatcattact tagattatag tagtttgaca caaactgaac gtgatcaact
     1921 caaacaaggt agacctgatg aatccaaaga gtcatatgct ttggattatg aaaaagacgc
     1981 actaccaaac acaggaagtt ctcaatctat tatgactgca ttgggtttgt tagctatcgg
     2041 gagtcttatt gtgattatca caaaagataa tagaaataaa aaaatagcta catttttgat
     2101 tgtaggggcg acaggtttag ttacactatc aactgcttca gcacttaatt tgaatgctaa
     2161 catccatgag tctggacgtg atggtgtgtt gcaaatttct ggttacagat atgttggtta
     2221 cttggagctt gatgataaaa ctgtttcgtc ggtttctcca gcatcaactg tttcgccagt
     2281 tgagcaaccc aaagttgtaa cagagaaagg cgaaccggaa gttcatgaga agcctgacta
     2341 tacgcaacca ataggtgcaa accttgttga gcctgaagtt catgagaaac tagcatacac
     2401 tgaaccagta gggacaacag gagtagatga aaatggaaac ttgattgaac cacctgttaa
     2461 cgacatccca gaatatactg agccagtagg tacaacagga gtggatgaaa atggaaactt
     2521 gattgagcca cctgttagcg acattccaga gtatactgaa ccaatatcta cagtttcaga
     2581 agttgcatca gaaagagaag agttgccttc tttacatacc gatattcgga cagagactat
     2641 tcctaaaacc actatagaag aatctgatcc tagcaaattt ataggcgatg attctgttag
     2701 acaagttggt gaggatggcg aacgtcaaat tgttactagc tatgaagagt tacatggcaa
     2761 aaaaatcagt gacccagttg aaacagtaac tattttgaaa gaaatgaagc ctaaaattct
     2821 tgtaaaaggt accaaagaaa aacctaaaga aaaaacggct cctgttttga ccttagatag
     2881 aacaaataca aatgtattaa accgatccgc aactctttct tatcatttag ttaatacaga
     2941 tggagtcaca atcaataaaa ttactgcgac aattaaagat ggaaatgaaa ttgtcaaaac
     3001 agtagatttg acttcagagc aattagataa gcaggtagaa gatttaaaat tctacaagga
     3061 ctataagata gagaccacta tgacctatga ccgtggcaag ggagaagaaa ctgcaacatt
     3121 agaagagaaa ccacttcgct tggatttgaa aaaagttgaa attaaaaata tcgcatctac
     3181 taatttagtg aaggtaaatg acgatggtac tgaaacacct agtgatttta tgactgaaaa
     3241 accttcagat gaagatgtga agaaaatgta cttaaaaatt actagtcgtg ataataaagt
     3301 aacacgttta gcagttgata aaattgaaga agtgactgaa gaaggtaaga aactttataa
     3361 aatcactgcc gaagctcaag atttgattca acatacagac ccaacgaagg ttcgtaacaa
     3421 gtatgttcat tatattgaaa aaccagttcc aaaagttgat gacgtttatt ataactttaa
     3481 agagttagta gatgccatga atgctgataa aaatggtaca tttaaaatcg gagcagattt
     3541 gaatgcaacg aatgtaccaa cacctaacaa acaatatgtt ccaggtacgt ttaagggaca
     3601 tctatcaagt gttgatggta aacaatatac aattcataac attgcccgtc ccttatttga
     3661 ccgtgttgaa aatggttctg tgaaaaatat taatttaggt aatatggata tcaatatgcc
     3721 ttgggctgac ggaatagcac ctgttgccaa tatggtgaaa aatgcaactg ttgaagatgt
     3781 taaggtaact ggtaatgtag ttgctaataa caatattgcg ggtatcgtca ataaaatcga
     3841 tagtggtggt cagttgacaa atgtagcctt catcggtaat cttacaggtg ttggtgataa
     3901 aggtcaatat atggctggca ttgccggtga gatttggaga ggtaatcttg caaaagcata
     3961 tgtcgaggct gatattgttg ctaacagagc ccgtataggt ggtttagttg ctaaaacaga
     4021 taatggtaac gactctatgg gaattggtaa atacggttca attcgtaaat cagtcaccaa
     4081 aggaaccatt aagactaaag ttttgtttga aacaggtgga tttatcaata gcaatcttcc
     4141 ttttggtaaa cttgaagata atatttcaat gatgagagtt gaaaatggtg aagagttctt
     4201 tggttcttcc gatttggact acgatggtgg ttatttcaca aatggctggt tagagcgtaa
     4261 ctttgttgtc aaaggtgtca gttcaggtaa gcattcatac aaacgttctc gtgacaaaat
     4321 taaagaaatt agtcaagatg aagctaataa gagaattgca aattttggac ttactgctga
     4381 taaatacgaa atcaacgaac ctgtggtcaa tcgcttaaat cgtttaacca gaagagaaga
     4441 tgaatataag tcaactcaag actacaaatc cgaacgtgat ttagcttatc gtaatattga
     4501 gaaacttcaa ccattttata ataaagaatg gattgtcaac caaggtaaca aacttgcaga
     4561 agattcaaac ttagctaaga aagaagtcct ttctgttacg gggatgaagg atggtcaatt
     4621 cgtgaccgat ttatcagata ttgataagat tatggttcac tatgctgatg gtactaagga
     4681 agaaatggat gttactaaga atactgattc taaagtccaa caagtgcgtg aatatagtgt
     4741 atctggtctt ggtgatgttg tttatacacc gaatatggtt gttaaaaatc gtgataaatt
     4801 gattgctgat gttaaatctc aattatcaag tgtggaattg atttcacaag aagtaagaga
     4861 tttaatgagt agacgtgata aacctgcaga gaatacggat gaacgtaaga atggttatat
     4921 taaagatcta tacttagaag aaagctttgc cgaagtgaag caaaatctag ataagttagt
     4981 caaatccttg gtcgaaaatg aagaccatca attgaatggt gatgaagctg cgataaaatc
     5041 acttctcaag aaagtggaaa ccaataaagc taaaatcatg atggctctga cttatctcaa
     5101 tcgttactat gatatcaaat acggtgacat aagtataaaa aacatcatga tgttcaaacc
     5161 tgatttttat ggtaaaacac caagtgttat tgacagactc atcaacatcg gttcaagtga
     5221 aaagaacttg aaaggggatc ggactcagga tgcttaccgt gaaatcatcg caggtaatac
     5281 tggtaaaagt aatttgcgta acttcttaga atacaacatg cgtctgttta cagaggataa
     5341 agacatcaat gattggttta tccactcagc taagaatgtt tatgtttcag aacctaagac
     5401 aacaaataca gagttgaaag ataaacgtca tcgtgtgttc gatggtttag ataacggtgt
     5461 tcatggtcgt atgattttac cacttctaac gcttaaagat gcccatatgt tcttaatttc
     5521 aacatataac acgatggcgt acagttcatt tgagaaatat ggaaaacata cagaagaagc
     5581 tcgtaatgag ttcaaaacta agattgatga agttgcacat gctcaacaaa cttatttaga
     5641 tttctggtcc agattagctc tgcctaatgt tcgtgataga cttcttaaga gtcaaaatat
     5701 ggtaccgaca ccagtttggg ataaccagac ctacaatggt tctcctgtag gtcgtcgagg
     5761 atttgacagt aaaggtaacc ctatagctcc aattcgtgaa ttatatggtc caacatggcg
     5821 acaccatgat agagactggc gtatgggcgc tatggcatca atattcccta atccaaataa
     5881 tgatgacaag gtcttgttta tggtgacgga tatgattagc ccatttggta tttcagcctt
     5941 tactcacgaa acaacacacg taaacgatag aatgctttac ttcggtggtc ataagcatcg
     6001 tcaaggtaca gacgttgaag cctatgctca aggtatgttg caaacacctg acagctcaac
     6061 gactaatggt gaatacggcg cacttggaat taacatggct taccatcgtc caaatgatgg
     6121 taaccaatgg tacaacccag atcctgacaa attaaagaca cgtgatgaca ttgaccgcta
     6181 catgagaaac tacaatgaag ctatgatgtt gcttgatcat gtagaagctg atgctgtact
     6241 tcctaaaatt aaaggagaca atagtaagtg gttcaagaag attgacaaag aaatgcgctc
     6301 taagattcag tataatgatc ttttaggtcc aaaccaatgg gatagtatcc gtgatttgaa
     6361 agatgaagaa aaggtaatga ctttatctag cgtcaatgat ttagtggata ataacttcat
     6421 gacaaaacat ggaaatccag gtaatggacg ttatagacca gaagatttta caccaaactc
     6481 agcttacgta aatgtcaata tgatggcagg aatttacggt gggaatacga gtcaaggtgc
     6541 tcctggttca ttatcattta agcacaatgc tttccgtatg tggggctatt atggttatga
     6601 aaatggcttt attagttatg tatcaaataa atacaaagca gaagcagata aaaacaacca
     6661 cggtttacta agcgataagc taataattaa taaagtatcg aaaggaaact ttaatactct
     6721 tgaagagtgg aagagacatt ggtacgggga agttcttgct aaagctaaga aaggttttga
     6781 ggctatcgat attgatggcg tccatatcag taactatgat gagttaaggc ctttatttga
     6841 taaagcagtt gaagaagatt tgaagaaacc agatgacttc tctcacactg ttgctcttaa
     6901 atctaaggtc ttcaaagccc ttcttaaaaa cacagacggt ttctttaata aactgtttaa
     6961 agaagacatt taaatgttta gaatatagaa ggaacagttt tttgctccct ctgaaaagtc
     7021 atcatttgat ggcttttttc tatatagggt aaaagatagg ctaaaagata gggtaaaagg
     7081 ctatcatcgg acaaaataaa gaaggcatga tataatataa agtagatttc tatgtcataa
     7141 aacaagaact gtttggacat cattcatttg aaaactctct atgttcaaac tatagtaaaa
     7201 taaaataggg gatctaaatc cttgctacga aaggaaaaaa ctcaatggct actattcaat
     7261 ggtttcctgg tcacatgtct aaagcgcgtc gacaggtgca ggaaaattta aaatttgttg
     7321 attttgtgac gattttagta gatgcacgct tgcctctatc tagtcaaaat cctatgttga
     7381 ccaagattgt tggtgataaa ccaaaactct tgattttaaa caaggccgac ttggctgatc
     7441 cagcaatgac caaggaatgg cgtcagtatt ttgaatcaca aggaatccag acgctagcta
     7501 tcaactccaa agagcaagtg actgtaaaag ttgtaacaga tgcggccaag aagctcatgg
     7561 ctgataagat tgctcgccag aaagaacgtg ggattcagat tgaaaccttg cgtaccatga
     7621 ttattgggat tccaaacgct ggtaaatcaa ctctgatgaa ccgtttggct ggtaaaaaga
     7681 ttgctgttgt tggaaacaag ccaggggtca caaaaggtca acaatggctt aaaaccaata
     7741 aagatctgga aatcttggat acaccgggga ttctctggcc taagtttgag gatgaaactg
     7801 ttgcacttaa gttggcattg actggagcta tcaaggatca gttgcttcct atggatgagg
     7861 ttaccatttt tggtatcaat tatttcaaag aacattatcc agaaaagctg gctgaacgct
     7921 tcaaacaaat gaaaattgaa gaagaagcgc ctgtgattat tatggatatg acccgcgccc
     7981 tcggtttccg tgatgactat gaccgttttt acagtctctt cgtgaaggaa gtccgtgatg
     8041 gcaaactcgg taactatacc ttagatacat tggaagacct cgatggcaac gattaaagaa
     8101 atcaaagaac tccttgtgac agtcaaggag ttagaaagcc ctattttttt agagcttgaa
     8161 aaggataatc gctcaggagt tcaaaaggaa atcagcaagc gtaaaagagc cattcaagct
     8221 gaattagatg aaaatttgcg cttggaatcc atgctttctt atgaaaaaga actttataag
     8281 caaggattga ccttaattgc aggtattgat gaggttggtc gtggtcctct tgctggtcct
     8341 gtagtcgctg cggccgttat tttacctaaa aattgtaaga ttaaaggtct caacgacagc
     8401 aagaaaattc ctaaaaagaa acatctggag attttccaag ccgttcaaga ccaagccttg
     8461 tcgattggaa ttggtatcat agataatcag gtcatcgacc aagtcaacat ctatgaagca
     8521 accaaactag ccatgcaaga agcaatctcc cagctcagcc ctcaaccaga gcaccttttg
     8581 attgatgcca tgaaactgga cttgcccatt tcacaaacct ccattatcaa aggagatgcc
     8641 aactccctct ctatcgcagc agcatctata gtagccaagg taacacgtga tgaattgatg
     8701 aaagaatacg atcagcagtt ctctggctat gatttcgcta ctaatgcagg atatggcaca
     8761 gctaaacatc tggaaggcct cacaaaacta ggagttaccc caattcaccg aaccagcttt
     8821 gaacccgtta aatcactggt tttaggtaaa aaagaaagtt aattgaaagg aaataccatg
     8881 gaggaacagt cggaaatagt ccgttctaag aaagaattcg cctttgcatc cagcactata
     8941 ctatcccaag ttggtcgagg aatcattgtc ggcctcatcg ttggaattat cgtcggatcc
     9001 tttcgtttct taattgaaaa gggcttccac ctgatacaag gagtttatca agatcaaggg
     9061 tacttagtgc gcaatctttt tgtactggtt ttgttttata tactcatctg ttggctcagt
     9121 gccaaactaa cacggtcaga aaaagatatt aaaggctcag gaattcctca agtcgaagcc
     9181 gaactgaaag gcctcatgtc cctcaactgg tggggcattc tttggaaaaa atatgtgcta
     9241 ggtattcttg ctattgccag tggactcatg ctgggtcgag agggacccag cattcaactt
     9301 ggagcagttg gtggtaaagg aattgccaag tggctcaaat ccagtccagt agaggaacgt
     9361 tccttgattg ccagtggagc tgcagcaggt ttagccgcag cctttaatgc tcctattgca
     9421 gcacttctct ttgttgtaga agaagtctat caccattttt cgcgcttttt ctgggtctca
     9481 actctagcag ccagcatcgt agcaaacttt gtgtctctac tcatgttcgg tttgacacca
     9541 gtattggata tgccagataa cattcctccc atgaccctag accagtattg gatatatctc
     9601 gtcatgggaa ttttccttgg attttcaggt tttctctatg agaaagctgt attaaacgtt
     9661 ggaagagttt atgacttgat tggtcaaaaa atccatttgg atagggctta ttatcccatc
     9721 ttggctttta tccttatcat accagtcgga atcttcttac ctcaaatcat tggtggcgga
     9781 aatcagcttg tcctttcttt aactgaacaa aattttagtt tccaagtttt attagcttac
     9841 tttttaatcc gctttatttg gagtatgatt agctatggaa gtggactgcc aggaggaatt
     9901 ttcctcccca ttttagctct tggttctttg cttggtgcct tagttggtgt tatctgtgtc
     9961 aatcttggac ttgtcagtca agagcaattc cctatatttg tcattctagg aatgagtggc
    10021 tattttggag ccatatcaaa agctccctta accgctatga tcctcgtaac tgagatggta
    10081 ggagatattc gcaaccttat gccacttggt cttgtcactc ttgtttctta tattatcatg
    10141 gatttgctca aaggtacgcc agtctatgaa gccatgctgg aaaaaatgct tccagaagaa
    10201 gtatctagcg aaggagaagt tacacttatc gaaataccag tttctgataa aattgctggg
    10261 aaacaagttc atgaactcaa cttaccacac aacatcctca tcacaactca agtccataat
    10321 ggcaagagcc aaacagttaa cggctcaacc agaatgtatc tgggtgatat gattcacctg
    10381 gttattccaa aaagtgaaat tggaaaagtc aaagatttgt tgttgtagta tgatcattta
    10441 cataatttat gttatgtaaa tgatcggttt gatttattta gaaaaccgat tctcagaaat
    10501 gagatcggtt attttttact
//
LOCUS       DAVLTG010000060        10316 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLTG010000060 DAVLTG010000000
VERSION     DAVLTG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.061"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            1..274
                     /locus_tag="VYN12_001763"
                     /pseudo
     CDS             1..274
                     /locus_tag="VYN12_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
     gene            complement(402..1424)
                     /gene="cbpF"
                     /locus_tag="VYN12_001764"
                     /pseudo
     CDS             complement(402..1424)
                     /gene="cbpF"
                     /locus_tag="VYN12_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1443..2264)
                     /gene="cbpG"
                     /locus_tag="VYN12_001765"
     CDS             complement(1443..2264)
                     /gene="cbpG"
                     /locus_tag="VYN12_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1416092.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVNTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGNWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(2345..2584)
                     /locus_tag="VYN12_001766"
     CDS             complement(2345..2584)
                     /locus_tag="VYN12_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416093.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(2734..3000)
                     /locus_tag="VYN12_001767"
                     /pseudo
     CDS             complement(2734..3000)
                     /locus_tag="VYN12_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3025..3336)
                     /locus_tag="VYN12_001768"
     CDS             complement(3025..3336)
                     /locus_tag="VYN12_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1416094.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3261..3502)
                     /locus_tag="VYN12_001769"
                     /pseudo
     CDS             complement(3261..3502)
                     /locus_tag="VYN12_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3503..4135)
                     /locus_tag="VYN12_001770"
     CDS             complement(3503..4135)
                     /locus_tag="VYN12_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1416095.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(4149..5144)
                     /locus_tag="VYN12_001771"
     CDS             complement(4149..5144)
                     /locus_tag="VYN12_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1416096.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5141..5839)
                     /locus_tag="VYN12_001772"
     CDS             complement(5141..5839)
                     /locus_tag="VYN12_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1416097.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(5916..6926)
                     /locus_tag="VYN12_001773"
     CDS             complement(5916..6926)
                     /locus_tag="VYN12_001773"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1416098.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(6910..7917)
                     /locus_tag="VYN12_001774"
     CDS             complement(6910..7917)
                     /locus_tag="VYN12_001774"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1416099.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRADIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFFAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(7904..8857)
                     /gene="mvaD"
                     /locus_tag="VYN12_001775"
     CDS             complement(7904..8857)
                     /gene="mvaD"
                     /locus_tag="VYN12_001775"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1416100.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(8839..9717)
                     /gene="mvk"
                     /locus_tag="VYN12_001776"
     CDS             complement(8839..9717)
                     /gene="mvk"
                     /locus_tag="VYN12_001776"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1416101.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQAVLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(9839..10168)
                     /locus_tag="VYN12_001777"
     CDS             complement(9839..10168)
                     /locus_tag="VYN12_001777"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1416102.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNDTLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
BASE COUNT         3019 a         2415 c         1818 g         3064 t
ORIGIN      
        1 agcgaaatta tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg
       61 ttggaacagg cattcacaga gaagcactat ggtggagtcc ttctttggga ttctgaaatc
      121 ggaaatgttt tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagccat
      181 tatagactat attgattatt acaacaacaa gagaattaag gtaaaactaa aaggacttag
      241 tcctgtgcag tacagaacta aatcctttgg ataaattatt tgtctaactt ttggggggca
      301 gtacagaaaa accttgatac tatgcgtttt ttgattgtga agacttttat ccacctatta
      361 tacaaagtta agtatccatc acagtttaca attagccttc attacttaac ccattcacca
      421 ttatagttta agtagtaacc acctactgtg gtattaacag ctaaagcacc tgaatcatag
      481 gcatagtacc agttaccatt gacttggaac cagcctgttt tcatatctcc attacttgca
      541 tttagatagt atcaagtcga accttcctga taccaaccag ttgccatagc tcctgatgaa
      601 cggagatagt accatttgtt cccaaggttt tgccagccag ttctcatatc accattttca
      661 gcatctagat agtaccaagt tgagccttcc ttataccagc cagttgccat agctcctgac
      721 gaatggaggt agtaccactt attacctaga tattgccaac ctgtttgcat aatgccagtt
      781 gctggatcta gatagtacca tggagctgct tttagcttct cttcatcata cgtaagaggg
      841 taatccttaa cccaaccacg tgctagctct ccaaccgtca atctgttgat gcgagaatca
      901 aagccaccat ccttctgtaa ataataccaa tgaccctctt cataaatcca accagttttt
      961 aaagtatgat aactacgctg atcttcaaaa taatagactc gtttctctgc ttggctatca
     1021 tattcttccc catgatgttt gttggtattc gtagcagttt ttgcttctaa aacttgcttg
     1081 ccaacaaatt cttgtaagac accatcttga ccaaaataaa accaatctgg tctaagagca
     1141 atctctattc ttggagaagg accaatcgta acccccttgt gtggagcagg tatatattgc
     1201 cagccgacaa ccatctctcc ggataaagga tcaaaataat agtacttccc atctatcact
     1261 ctccagtagg tttcttttag agcccccttt ttgtagtagg ttctaccatt ttctttgaca
     1321 aactgccatc cttcagaatc atctgcaaat actgtactgg tccctagcaa accgaagaaa
     1381 aatgtggcta gtgcgacttg catcattttt ttcaaaagct tcattttata tatcctccaa
     1441 catcaaatcc actcaccaga tgaagcgaag ttataaactt taccatcgat agtttggcta
     1501 cctgtaacca ttgctccatt tgaattgaga taataccagt ttccatttac tttttgccaa
     1561 tctgtaagca tcttaccgga actgtctaaa taataccaag tatcatttat ctcctgccaa
     1621 cccgtttgtt tatcatgttg tctataatag taccaactac catttatttt cttccatcct
     1681 tcaagagagt aacctttaag aaccgaataa ataaatggca aatttcgttc atttaattta
     1741 actgcactgt taatttgatt agctccatct cctaaagtat gcactcctac tacacggtga
     1801 ctagcatcat aaactgtaga tccactagac ccctctaaag tattaacttg gtaatccaag
     1861 aacatgccat catcacttaa aacttgtttt ttatctgtat acatttgatg aattttaaaa
     1921 ttatatgata gatagcctgt gatagtcaca gttattcctg tcaaattttt ttgactagta
     1981 ggaagaccca aagtccctaa ttttgcacca atgggctctt ctagaattaa taaagccaag
     2041 tcatattccc ttgcatcctt agaatttaaa tttctaaatt ccttcaaata acgaacttcc
     2101 tttactttga tctttccaaa tagttcttga cttggactaa cagccggaag aacataaata
     2161 tcatccgctt ctttcccata gtcatgtctg tagtagttgt gagccgctgt aattaacaca
     2221 ttatctttaa taaaattcgc acttcccctc ccttctacat tcattccatc ggctactcca
     2281 taatacttag ataaaaccat agctgaagtc gaatacggat actgtaaagt attatcaatt
     2341 ttaatcaaat catcattacc gataatactt ctgattgctt ttggtagtat gaaccatacg
     2401 ttggtgaaat ctcagataat gaagaatcat tagactctgg acctttttct agtgtctcac
     2461 ttacctcata ttcttcacct gtactagaaa taacactcaa agcagatact gtcgataact
     2521 ggctagccaa taaagtactc gcaataattg aaatacccaa ttttttataa acagttttct
     2581 tcattattgt atcctcctaa tgtaattata gcgtactatt ctaaatttct taatctacta
     2641 tagaatcaag aaatctacca ccttctttaa ataccctcca ttatcacata aacaggtaaa
     2701 cttttcaatt aatgactgcg cttttcaatc acgctagagg tacttgcttg cttctttgat
     2761 actaagttca gccattcttt ccttgttttt ctcaataaag catgttaccc aagtgggatt
     2821 cgttttggag tagtctcgca gagtccagcc aatggcttta ttgataaaaa attctgtttg
     2881 gttcaagtta tgaagtagaa tcttttccat taattgagta ttggtcttct cttttcttaa
     2941 caactggtgg tcaatagcga cacgtctcag ccagatatta tctgataggc tccattttat
     3001 actcaatgaa aatcaaagag caaactagga agctagccgc agattgctca aaacactgtt
     3061 ttgaggttgc agatagagct gacgtggttt gaagagattt tcgaagagta ttaagattat
     3121 ttcttctagt tcagagtgtt catacaccaa actccctact actcgatcta ggatatctac
     3181 cgtgtcccac caggattttg tcacgactaa ctgctctagc ttaggcaaat cggtttcctt
     3241 tagataagac tgcattgctt tcaaatagtt agcagccaca tattggtatt ctctaggatc
     3301 cttttcccag caagtgtctg caaaatccca atcgataatc tttgtttttt tcgcttctgg
     3361 aaaatatttt tatagagttt atttctttca ggcaccgcaa tacctagaaa agaaaattga
     3421 tggcgcatat aggcttccat gggccttgct ttttagagtc ttttgctgct tctagctcct
     3481 caagtaaatc tgctaaactc atctaaaact cctcatgccc caccaaatgg tgctgaaagg
     3541 catagacagc cgcctgggta cgatcgctga cttcaagttt ggcaagaatg ttggacacgt
     3601 gggtcttgac cgtcttgaga gagataaaga ggtcatctgc gatgcgctga ttttcgtagc
     3661 ccttggcgat gagttggaga acatctcgct cacgcgcagt caattcttca tgaagttcca
     3721 tatgattgcg gtggtattca accttcttgc taacctcttg ctcaatggcc agctcgccag
     3781 cagctacctt actgacggca tgaagcaatt catctgcact agaagtcttg agcatatagc
     3841 ctttggcacc agcatctaag actggcatga ttttttcatt gtccaaataa gaggtcacaa
     3901 tcaaaatctt ggcttcaggc cattctttaa ggattgctaa ggtcgcgtca atcccattca
     3961 tctcaggcat gacaatatcc atgacaatga catctggacg cagttccaag gccaagtcaa
     4021 tcccttgaga cccgttggac gcctcaccta caacttctac atcgtcttgg aggtcaaagt
     4081 agcttttcaa gcccaatcgg accatttcat ggtcatctac tagtaaaatt ttcatcttta
     4141 ctcctttatc attccttatc taacagggga atacggatat caaccgccag cccttgcttg
     4201 ggagctgtca agagttgaac tgttccagcc atatcttcaa cccgctcctt gatatttcgc
     4261 agtccataac tcaagtcgtc taagctccct aactggaaac caatcccatt gtccaccacc
     4321 ttcagttgca attcaacatc tgtctgatag aggtagacat ctaggcaaga tgcctgggca
     4381 tggcggagcg tattgctaat caactcttgc aggatacgga agatatgctc ctcgattttc
     4441 ttaggcaatt tcgtcatatt ctgcttgaga ctaaccctaa gatcactctt gtcctcaagc
     4501 tcttttaaaa gaatttgaat cccttctatc aagctcttct gctccagttc aactggtcgc
     4561 aaatgcaaga gcaaaacccg caaatccttc tgggctgttt ctaaaatagc tgtgacactc
     4621 tgcaactggg tctgcatctt ttctctatcc aatttcaaag cctgctgact gatacccgat
     4681 aaaatcatgt gggccgcaaa caactcctga ctgactgtat cgtgcaaatc ccgagcaatt
     4741 cgcttccgtt ccttctcgat gatttcctct tcctgagcaa ggctatgatt ttcagctttt
     4801 tgaagagcct ctgtcaaaag gttaagttta cctgataagg acttgaaact ggcatccaaa
     4861 tctggatcta caacctgaac cacttcttgc cctgccaata aacgcttgag attagcctgc
     4921 atttttctta gagaaagctc ttcgatccct cgccaaaaca gggctaagag acaggtcatg
     4981 gacatgctga aaaccaacaa taaaaagaaa aatttttctg ttttttcgac atcgtgcaaa
     5041 aagatagacc agtcaaaatc aagtatttcc agcaagctat gggagaaaaa aaagacaaac
     5101 aggaaggagg tgagagcgat aatgacatag gcttgttttt tcatcctcta accacctcaa
     5161 catcaccaat catagtggtc aagaaaatct tgacactctt gttactcttg agatagtctt
     5221 ttgtttcttg atgatagtgt tcattgcgga gggctcgctt gggctggttg aaaaaagtca
     5281 aatccccata gagacagtta acgctgagac tgacttccac atctacaggt acgatgattt
     5341 tggtcgttcc taccatcttt ctgaggataa tgacattgtc atgattggtt aagatgaccc
     5401 tctccagatg aatagtgtcc ttgcccatga agcgaaagag attgatatca tcaaattggc
     5461 aagtctggta gcttgaaaaa tgatgaagat ttccaaacca acgatttttc tccttcttaa
     5521 ccgtcacaac ctcttcaaaa accaaattgg tctgctcttt ttcctggttc atcatcgggt
     5581 aaagaagaaa gagactatag ataaccgcaa caaaaatagc tagaatcaca aaaggattga
     5641 gcataacgat gaaaaagaag agaatggttg ccgctactaa aagaagatta ttcccctctt
     5701 taccagtgta gtagcgaatc aaaagcaaaa agaggaatag tatcagcaga aaacgcgaaa
     5761 aatgctctga taccatcaaa atcagagctc ctgtcagaag acaggcttcg ataaataaaa
     5821 agattttaaa ttttctcata ggttcatcct ctcccttcta ttttatcaca attcaaaaaa
     5881 gtcacctcag tctgaggatg gaaaaaaggc gctggttacg cctttttcat ctgatccttt
     5941 gcttctttta attttccata aagaagatag tctacttttt gtagatctgc tatggtggca
     6001 cagttaaggg aacacataat caagcgtagg tctgctttcc agccttggac aatgccaatc
     6061 acttcttcaa ctgtgtaggt ttcaaccaat tccagaacgg ttcgtgacaa tcccacagac
     6121 ttagcaccaa aaaccaagca cttaatcata tccagcggat tccgaacccc tccactaacc
     6181 aagagttcga ccttatcttt ccattcttgg gcattgagaa gggcctgcat ggtagactga
     6241 ccccattgat tgaggtaatc acgctggcca ctacgacggt tttcgatata ggcaaagctg
     6301 gtgccaccac gacccgatag gtccactgta cgaacaccga attcataggc tctttcgatt
     6361 gtcttggcat ccattccaaa gcccacttcc ttgaggacaa taggaacggg aatttgctcg
     6421 ctataatctg ctagatgcga ttgccagctt ctaaacttcc tttctccctc gggcatgagt
     6481 aattcctgca tgacattgac atgcacttgc aatagaacag gattcatctc ttctacagtc
     6541 tgaagtccta actcgacagg cttgtccaat ccaatattgg ttccaaggag gagattggga
     6601 tgactagact tgacagaaaa agaatcatcc gttggatttt tgagggctgc gctataagaa
     6661 cccgttacaa ataaaatacc acaggattcc gccacctgag ccagcttttg attgatttct
     6721 cttcccttat tacttccacc agtcatggca ttgatataaa aaggaaagtc ccactttcga
     6781 ccagcaaact ctgtcgaaag atcgatttca tccagattgt aaagaggcaa ggaagaatga
     6841 atcagctcca cctcatcaaa gctattatag gaacttttct gctcaagggc atagaggata
     6901 tgctcgtcct tacgatttgt cgtcatgtcc tatcctttct tgatataaga gctcaatccc
     6961 cagatcggcc caacgatttt ttaaggtttc ggttgattgc gcatcaaaac tcaaggcgat
     7021 gccacagtca ccaccaccag caccactact cttggcaacg gcctgcaaat cttgactggc
     7081 ttctttcaac tgtctaagca aaggcgtgta aatatctgta ctcaagcctt ctaaaagctt
     7141 gctggctact tctacttgct cgataacttt ttcggctttc ccctgctcca aggcttcgac
     7201 caaagaaacc accgtttctt ttgaggaact taaaaaattt tgattgatat tttgcttgat
     7261 ttgctggacc atgtgactcg atacagccac ttccttggtc catcccacta agaaatcaca
     7321 ttctaaagtt ggtttcactt gtgagataaa aaatccccaa tcacgctcca gaactgtcgc
     7381 caagttttct tcttctaacc aagcagccac cttctggcga tcaaatgact ggtagagaac
     7441 caaatcctct gccacaatac aggcaaggtc gcccatggaa ccattgtctc ctcgcttgag
     7501 caagacagcg ctagtcagct tgaacaagag ctcctgatca acagaaacat catacagagc
     7561 cagtaaagcc ttgacaacca agacaacgac gctgccacta gaacctagac caaacttttt
     7621 cccttctcgt tccattttgc cacagatttc tagggaaaaa ggtcttaaat tctgaccgcg
     7681 aacagcgaag aagtctccca tcaaagcaat cgtttcttga atcaagctgt agtcaggatt
     7741 gggccttaag tccactgcga aatcaaacat atctgaatag atacggtagc tgtcagaaaa
     7801 agcaatatca gccctcatat agatgggaat atcctttatc aaagctaact gccctggctc
     7861 taaaatagca tattcacctg cccaatagag ttttccgcaa gttttaacag caatcatctt
     7921 gactcaaatc ctttgttttt gacacaatca agcgataacg ctgaccgaaa atttctgata
     7981 aatgctccaa gtctttctcc tgacagaaga ccttaacatt gggaccagca tccatggtaa
     8041 agtagcaggc ctctcctttc tcacgaagct ggcgaacaaa gtccatagcc tcataagagg
     8101 catccgtcag ataagaaaag gctggactag cagtctttgt cgtagcatgc atagccaggg
     8161 catttttctc cgttaattct ccaatcttgg caaaatcatt ttccttgaga taaatcagca
     8221 tatcctgata gtccttctca gactgacgaa cccagtcgtc aaaagtcgtc gaggtttcca
     8281 cacaaagttt catcccatca cggctagaga ttggtttttt cttgtcctct agcaccaaca
     8341 taatcatagc tagtttcaag tctgtctcta cagggtaaat ttctccacta tccttatccc
     8401 aggctcctag tggtccataa aaactccgag aagaagagcc tgaggcaaac ttggcttcct
     8461 gcgctaactg acttctatcc aatccaagct tgaaataagc attacaagcc ttgaccaggg
     8521 cggacaaacc actagaactt gaggacaggc ccgctgccgt aggcatattg ttttgagtat
     8581 cgatacggac aaagccctca ccagctggac gataacggtc aataatctta ctcatcttgg
     8641 catgctcgac ctcattttgt agctgaccat tgatgtaaaa ttcgtcagct gttacattgg
     8701 ctggtaaagg cgacaaggtc gtctctgtat acatattttc caaagttaga gaaatactgc
     8761 tagtagcagg caccatctct ttttcttttt tctttcccca atatttgata atagcaatat
     8821 ttgcgtagga acgtactgtt acaggctctc tatccatgtc tgaacagctc ctttctcttc
     8881 taatctttct gctagttctt gtgcgtgtgt caaattggtt accaaggcta tgatacaacc
     8941 tcctagccca ccaccgctca tcttggcacc cagagcacca tggctaagag tcgtttcaac
     9001 caaaaagtct gcctcagggc tactgactcc aatttctttt aaatgtaaat gcgcttgact
     9061 gaggatttgt cccagtcctt cagcatcttt ttgtgaaatc gcaacttctg cttgctgggt
     9121 taattctccc aaggcatgca aaaacggtag ggcatccttg cccttatttt gaaccacttg
     9181 gatggcttca cgagtatgac cataaacacc cgtatcggca atcaccaaat aggcggataa
     9241 atccatctca agttctgtaa atcctacgtt cttgataaag cgaataggtt ggtcactgag
     9301 acaggtctta gcatccaaac cactaggatt catatgggca atcatttcag ctcgattgac
     9361 caagatttct agtacatcat gaggcagaac agcctgatag tagtcaaata ccgcacgaat
     9421 ggccgctatg ctgatagccg ctgacgaacc catcccccgt ttctcaggga tagccgagtc
     9481 aatctcacaa cgaatgcagg cttctgtgat atccaaatac tccagtgagg cataaaccgc
     9541 catggacaag gtatcctcct cataaaggcg ccaaggactc tctgcaggaa ctaccttaca
     9601 ggtcacctcc acctccaaaa gaggcaggga aatggcagga taaccgtaaa cgaccgcatg
     9661 ttcccctatt aaaattatct tactatgtgc ctggccgaca ccaacttttt ttgtcatttt
     9721 ttccttttac tagacgaaaa aacgtcttat ttttcataca aatattaatt ctttcctatc
     9781 tattttatta tattttcaca aaaaaagcga ttgtttccat tcacaatcgc ttctttcatt
     9841 attgaaccca ttcgccatta tagttgacag aatagccatc tacggtcgta ttcactgcca
     9901 aggcacctga gctataagcg tagtaccatc tgccattgac ctggaaccaa cctgtcgtca
     9961 tagaacgacg aaagaaactc cataccatta agtaaagagg aaagtcgtga gggagcatgc
    10021 gccattgaca acctgtttta gtgacgtaca aagtatcatt aacaagtact cgtttcggcc
    10081 atttataggt gcggtgtttg gagaaatagg gttcaatctt cgcccattct tgatcgttta
    10141 aatcagtatc atatgcttta cgtatcataa ctctagttta acattttttt gtgaatacag
    10201 gttctaaata atcgaccacg aaaatttctt aagtggaaaa cgccttatga agtatgctac
    10261 gggaaagtta tgcacttaat ttgacaattc aagatgtaaa aatatatact atagta
//
LOCUS       DAVLTG010000061        10316 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLTG010000061 DAVLTG010000000
VERSION     DAVLTG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.062"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            141..950
                     /locus_tag="VYN12_001778"
     CDS             141..950
                     /locus_tag="VYN12_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1416103.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            955..1656
                     /locus_tag="VYN12_001779"
     CDS             955..1656
                     /locus_tag="VYN12_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1416104.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1681..2598
                     /locus_tag="VYN12_001780"
     CDS             1681..2598
                     /locus_tag="VYN12_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV1416105.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2626..4167
                     /locus_tag="VYN12_001781"
     CDS             2626..4167
                     /locus_tag="VYN12_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV1416106.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4186..4644
                     /locus_tag="VYN12_001782"
     CDS             4186..4644
                     /locus_tag="VYN12_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1416107.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4646..6868
                     /locus_tag="VYN12_001783"
     CDS             4646..6868
                     /locus_tag="VYN12_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1416108.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6908..8017
                     /locus_tag="VYN12_001784"
     CDS             6908..8017
                     /locus_tag="VYN12_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1416109.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8174..9064
                     /locus_tag="VYN12_001785"
     CDS             8174..9064
                     /locus_tag="VYN12_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1416110.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9089..9412
                     /locus_tag="VYN12_001786"
     CDS             9089..9412
                     /locus_tag="VYN12_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416111.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9402..>10316
                     /locus_tag="VYN12_001787"
     CDS             9402..>10316
                     /locus_tag="VYN12_001787"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1416112.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVA"
BASE COUNT         3546 a         1497 c         2034 g         3239 t
ORIGIN      
        1 attatatttt tatgtttgtt gttctgttat gaaacgaaag aaattggaaa ctagtttcta
       61 atttatgaaa aatattgaaa aaaaaaaaaa aaagtgttaa aataaagaat gtaaacgttt
      121 acttcaacta aggagctcat atgttactgc aaaaagaact aattccaatg atagaagcta
      181 acttaccaaa tatggcatat gctgaaaaag acattgctaa attcttctta aaacagcaac
      241 ctctgaatga ttattcatct aaagcattgt gcgaatacct taatgtatcc aaagcaacat
      301 tgactcgatt tgcgaaaaaa tgtggtttta aaggttttag acaattcatt ttcaaatacc
      361 aagagatgat tcatgagaaa gaaaagttgg cattatatac agaggcaaca gaaaaagttt
      421 tatccgacta tgaggaaatg ttgagaaaaa cttacacggt tcttgatgaa gttcaacttg
      481 agcgtattgc tgagatgata gaaactgctg agcgtgtata tctctacggt aaaggaagtt
      541 ctgttcttgc tttacaagaa atgaagatga gatttatgcg tctcggagtg attggtgaag
      601 tattatcaga cgaggatatg attttgtgga gtagcttact acttaatgaa aattgccttg
      661 tcattggagc atccatttca ggtcaaactg atattgtact agaaggtcta caaaaagctg
      721 cagataaagg cgctaaaaca gttttaatga ctacaagaaa atttgacgaa gaagattgtt
      781 tctttgatga actattgtta ttagcttcga ccgatcatct ctcgtatggc aatcgcatat
      841 cacctcagtt tccaatactt ttaattacag actgcttatt ctctaattat ctggaaagtc
      901 cagagagaca atattattac aatcaaacta ttatccataa ggaggaataa taaaatgagc
      961 caaatttgga ctaaagaaaa atttataagc caagttcaag gtggagtcat tgtttcttgt
     1021 caagctttac ctggtgaagc cctttataat gaagaattta gcttgatgcc ttttatggct
     1081 aaagcagctt tagaggcagg agcagtgggc attcgcgcaa attctgtgcg tgatattaaa
     1141 gcaattcaga aagtagtaga tttaccaata attggaatta tcaaaaggga ttatccacct
     1201 caagaaccat atattactgc tacgatgaaa gaagtagatg aacttgtaga atgcggaaca
     1261 acagtcattg catttgatgc aactttaaga ccaagatatg atggcttagt tgtcagtgaa
     1321 tttatcaaaa aaataaaaga aaaatatccg aatcaattgc tgatggcgga tgtaagtaat
     1381 ttagatgaag gtctctatgc atttaaatca ggcgttgatt ttgttggtac aacattatca
     1441 ggttacacaa gtacaagtgt acaatcagat gagcctgatt ttgaactaat gaaaaaattg
     1501 gctgatttta atattccggt aattgccgaa ggaaaaattc attatccaga acaattaaaa
     1561 aaagcttata gtttaggtgt taccagtgta gtcattggtg gagcgattac acgtccaaaa
     1621 gaaattgctc agcgatttat taatgtcatc aaataaaaaa caatataaag gagaaatctg
     1681 atgaaagatt taactaaata caaaggcgtt atccctgcat tttatgcttg ctatgatgaa
     1741 aatggtgaaa ttagccaaga tcgtgtaaaa tctctggtac aatatttcat tgacaaaggt
     1801 gtaaaaggta tctatgtaaa tggttcttca ggtgaatgta tttaccaaag tgtagaagat
     1861 cgtaaacaaa ttattgaagc tgttatggaa gttgctaaag gtaaattaac agttatcaac
     1921 catattgcat gtaataacac gaaagatagt atcgaattgg caaaacattc agaaagtgtt
     1981 ggagtcgatg ctattgcagc tatcccacct atttatttca aattgccaga gtattcaatc
     2041 gcagcatatt ggaatgcaat gagtgaagct gcgtcaaata cagattttat tatctataat
     2101 attccacaat tggcaggggt tgcgttgact ggtagtttgt atgcaacaat gcgtcaaaat
     2161 cctcgtgtga ttggagttaa aaattcttct atgcctgtac aagatattca aatgtttgta
     2221 gctgcaggtg gagaagatta cattgtattc aatggtccag atgaacaata tcttggtggt
     2281 cgcttgatgg gagcagaagc tggtattggt ggtacttatg gcgttatgcc agatttgttc
     2341 ttgaaattgg aaagtttgat tcaagaacga gatttagata cagctaaaaa acttcaatat
     2401 gctatcaatg aagttatcta taagatgata tcaggtaagg caaatatgta tgctgtagca
     2461 aaagaagttt tgcgtctaaa tgaaaaactt gatttaggtt ctgttcgtca acctttagaa
     2521 gcattggcag aaggtgactt ggaagttgca aaacaagcag cagaacttat tcaacaagca
     2581 cgaaaagaat ttttataata aataaaatca atatggagat atgttatggg cacaacagga
     2641 tttacaataa ttgacttaat tatcttgatt gtttatttac ttgcggtgtt ggttgcaggt
     2701 atctatttct ctaaaaaaga gatgaaagga aaagagttct ttaaaggaga tggttcggtt
     2761 ccttggtatg ttacttcggt atccattttt gccacaatgc tcagtccgat ttccttcttg
     2821 ggactcgctg gtagctctta tgcaggtagc tggattttat ggtttgctca attagggatg
     2881 gtagtagcta ttccactgac aattcgtttt atcttaccta tctttgcacg gatagacatc
     2941 gatacggcat atgattactt ggataaacgt tttaattcta aagcacttcg tattatttca
     3001 gcactcttgt ttattattta tcaattggga cgtatgtcta tcattatgta cctcccatca
     3061 gctggtttat cagtattgac aggaattgac atcaatattt tgattatttt gatgggtgta
     3121 gttgcaattg tttattctta tactggtggt ctaaaatccg tattatggac agactttatt
     3181 caaggtgtga ttctgattag tggtgtcgtt ttagctttat ttgtactgat tgctaatatt
     3241 aaaggtggct ttggtgcagt agcagaaaca ttagcaaacg ggaaattcct tgctgcaaat
     3301 gaaaaacttt tcgatcctaa cttgctttca aactccatct ttttaattgt gatgggttca
     3361 ggctttacaa tcttgtcttc ctatgcttca tctcaagatt tggttcaacg ttttactaca
     3421 acacaaaata ttaagaaact taataagatg ttgttcacaa acggtgtttt gtcacttgca
     3481 actgcaacag tcttttactt gattggtaca ggcttgtacg tattctatca agtacaaaat
     3541 gcagatagtg cagctagcaa tatccctcaa gaccaaatct ttatgtactt tattgcatac
     3601 cagttaccag taggtatcac aggtttgatc ttggcagcga tttatgcagc atctcaatca
     3661 actatttcaa caggtttgaa ctctgttgca acttcatgga cattggatat tcaagatgtc
     3721 atttctaaaa atatgtcaga caatcgtcgt acgaaaattg cacaattcgt atctctagca
     3781 gtaggtttat tctcaattgg tgtttccatt gtcatggctc actcagatat taaatctgca
     3841 tacgaatggt tcaatagttt catgggactt gtacttggtc tacttggtgg tgtatttatt
     3901 cttggatttg tttctaaaaa agcaaataaa caaggtgctt atgcagcgct gattgtatca
     3961 accatcgtca tggtatttat taaatacttc cttcctccaa cagctgttag ctactgggca
     4021 tattcattga tttcaatctc tgtatcagta gtttcaggtt atattgtatc tgttcttact
     4081 ggaaataaag tatctgcacc taaatataca acgattcatg atattacaga aattaaagcg
     4141 gattcaagtt gggaagttcg tcactaatag aaaagagaaa ataatatgat tatttctgaa
     4201 caatctgatt ttaaacgata tgcttctgtc aataaatatt tttcaaaagt ctgtgatttt
     4261 ttagaaaata caaatttgac agatttagtt gatggaaaaa ttgatattga cggggaaaat
     4321 gtttttgcaa attgtatgac ttatctagct gatggagttc caggagatat ttttgaaact
     4381 cataagaaat atttagatat tcatattgtt gttgaaaata ctgaaaaaat ggcagtaact
     4441 tccccagttc gtgcccagtc acgtgtacct tttagcgaag agaaggatat tgctttttac
     4501 gatagcaaag actatcaaat tgttgaattg cttccaggga atatgttggt gacttttgaa
     4561 gaagatcttc accaaccaaa gattcattgc aatgatgaaa cggttaaaaa acttgttatc
     4621 aaagttttaa acgaggaaaa ataaaatgaa aaaaaatatt aaacaatatg taaccttagg
     4681 tactgtagtg gtattatcag catttgttgc taactcagtt gcagctcagg agactgaaac
     4741 ttctgaagta tcaacaccaa agttggtgca acctgttgca ccaacgactc cgatttcgga
     4801 agtacaacct acatcggata actcttcgga agttactgta caacctcgaa cagttgaaac
     4861 tactgttaag gatccatctt ctacagcgga agaaactcct gtcttagaaa aaaataatgt
     4921 tactttaaca gggggcggag aaaatgttac taaagagtta aaggataaat ttactagcgg
     4981 tgactttact gtagtgatta agtacaatca gtcaagtgag aaaggcttac aagctctgtt
     5041 tggaatatct aattccaaac ccggtcaaca aaatagttat gtagatgtgt tccttagaga
     5101 caatggtgag ttggggatgg aagcgcgtga tacttcttcc aataaaaata acctagtatc
     5161 cagacctgct tcagtttggg gtaagtacaa acaagaggct gtgactaaca ctgttgcagt
     5221 agtagcagat tcagtcaaaa aaacatattc tttatacgca aatggtacaa aagtagtaga
     5281 aaagaaagtg gataatttcc taaacatcaa ggatattaaa ggtattgatt actatatgct
     5341 tgggggagtg aaacgtgcag gaaaaacggc gtttggtttt aacggaacac tagaaaatat
     5401 caaattcttt aatagtgcat tggatgaaga aactgttaaa aagatgacaa caaacgctgt
     5461 tactggacat ttaatttata cggctaatga tacaacaggt tctaactatt tccgtattcc
     5521 agttctgtat acttttagca atggtcgggt attttcaagc attgacgctc gttacggtgg
     5581 aactcatgat ttcttgaata aaattaatat tgctacaagt tatagtgatg ataatggtaa
     5641 gacatggact aaaccaaaat taacattggc attcgatgat tttgcgccag taccattaga
     5701 atggcctcgt gaagttggtg gacgtgactt acaaatcagc ggtggtgcaa cctatattga
     5761 ctctgttatt gttgaaaaaa agaacaaaca agtactcatg tttgctgatg tgatgcctgc
     5821 tggagtaagt tttagagaag caactagaaa agattcaggt tataaacaaa ttgatggtaa
     5881 ttattacctt aaattaagga aacaaggtga tactgattac aattatacta ttcgtgagaa
     5941 tggtactgta tacgacgatc gtaccaacag accaactgaa ttttcagtag ataaaaattt
     6001 cggtattaaa caaaatggta attatttgac ggtagagcaa tattcggttt catttgaaaa
     6061 taataaaaag actgaatatc gtaatgggac taaagtccat atgaatatct tctacaaaga
     6121 tgcattgttt aaagtagtgc caacgaacta tattgcatat atttctagca atgatcatgg
     6181 cgaatcttgg tctgcaccaa ctttattacc tcctataatg ggacttaatc ggaatgcgcc
     6241 atatttaggt cctggacgtg gaatcattga aagctcaact ggacgtattc ttattccgtc
     6301 ttacactggt aaagagtctg cgttcattta tagtgacgat aatggagcat cttggaaagt
     6361 taaagtagtg ccacttcctt ctagttggtc agcagaagca caatttgtag aattgagtcc
     6421 aggagtaatt caagcatata tgcgtacaaa taatggtaaa attgcatatt taacaagtaa
     6481 agacgcaggt actacttgga gtgcaccgga atatttgaaa tttgtttcaa atccaagtta
     6541 tggaacacaa ttatcaatca tcaattatag ccaattgatt gatggtaaaa aggctgtcat
     6601 tttaagtact ccaaactcca caaatggtcg taaacacgga caaatttgga ttggtctaat
     6661 taatgatgat aatacaattg attggcgtta tcatcacgac gttgattata gtaactatgg
     6721 atactcatat tcaacattga cagagttacc aaatcatgaa attggattga tgtttgaaaa
     6781 atttgattca tggtctcgta atgaacttca tatgaaaaat gttgtaccat atataacatt
     6841 taagattgaa gatctgaaaa agaattaaag ctgaaatttg aaaatatata aaaagaggat
     6901 aaaaattatg gtaaattacg gtattgttgg agctggatat tttggagctg atttagctcg
     6961 ctcaatgaac aaaattgaag atgcaaaagt ggttgcggta tttgacccaa atcatggaga
     7021 agaagttgct caagagttgg gatcagatgt ttgtgcaagt ttagatgaac ttgtagcacg
     7081 tgaagatatt gattgtgtga tcgtagcttc acctagctac cttcaccgtg aaccagttgt
     7141 gaaagctgct caacatggca aacacgtatt ttgtgaaaag ccaattgcat tgtcttatga
     7201 agattgtaaa gccatggttg acgcatgtaa agaaaataat gtcatcttta tggctggtca
     7261 catcatgaac ttctttaacg gtgtacacca tgctaaagaa ttgattactc aaggtaaaat
     7321 cggtaaagtt ctttattgcc atgctgctcg tacaggttgg gaagaacaac aaccaactgt
     7381 atcatggaag aaacttcgtt ctcaatctgg aggacatttg taccaccata ttcatgaatt
     7441 agattgcatt cagtttatca tgggaggact tcctgaaaaa gcgacaatgg taggaggcaa
     7501 tgtatatcat aaaggtgaaa actttggtga tgaagatgat atgctcattg taaacttaga
     7561 atactctgat gatcgttatg ctgttttgga atatggtaat gctttccgtt ggggtgaaca
     7621 ctacgtcttg attcaaggaa ctgaaggagc tatcaaactt gacttgttca atactggcgg
     7681 tactcttcgt gttaaaggtg aaggagaatc acacttctta gttcatgaaa ctcaagagga
     7741 agatgatgat cgtacagcta tctataccgg tcgtggtatg gatggagcaa ttgcgtacgg
     7801 taaaccagga gtacgttgcc cattatggtt gcaaacatgt attgataaag aaatggaata
     7861 tctacatgac atcattaaag gtggagaaat tacagaagaa tttgaaaaac ttctcaatgg
     7921 tgtagctgct ttagaatcaa tcgctaccgc tgatgcatgt actttatcag ttaaagaaga
     7981 tcgaaaagta agtctttcag aaatcacaaa tgcttaactt ttgtaaaaca gaatagtaaa
     8041 ttcttgtcat tatataattt ctaaagttct gtgatacaac tcattgaata aagaaataga
     8101 gatgggactg ggataatgcc cagtcccatt ttttatcaaa aagtaatgag atcaaaaatg
     8161 tgggagtgtt gaaatgaaga ttataggtat cgatattggc ggaacaacaa ttaaggcaga
     8221 tttatacgat gagtttggaa cgagtttgaa tcatttcaaa gagatagaaa caattattga
     8281 ctatgatttg ggaacgaatc agatattaaa tcaggtctgt gatttaattg gtgagtatac
     8341 tttaaatcat tcaattgatg gtgttgggat ttccactgct ggagttgtta atgctaatac
     8401 tggagaaatc atctatgcag gctatacaat accagggtat atcggagtaa actttactgc
     8461 cgaaatagaa aaacgttttg ggttgtatac ttttgttgaa aatgatgtta attgtgctgc
     8521 attaggtgaa ttgtggaagg gacaagccaa agataagaaa aatgtagtaa tggttactat
     8581 tggaacaggt ataggaggca gtattattgt caacggacaa attgttaacg gatttaacta
     8641 tactgctggt gaagtaggtt atattcctgt aggtaattcg gattggcaaa gtaaagcctc
     8701 aacaaccgca ttgattcatt tatatcaaaa aaagagcttg aaaactaatc aaactggacg
     8761 tactttcttc actgatttaa gatctggaga taaagttgct gaagaaactt ttgaaatttt
     8821 tgtagaaaat ctaacaaaag gtttattaac gatttcttat ctacttaatc cagaaattct
     8881 catattagga ggtgggattc tggatagtaa ggatattttg ttacctgaaa ttcaaagttc
     8941 tttagctaaa aatgcaatgg ataataggtt tttacctaaa aatcttgtgg cagctacatt
     9001 aggaaatgaa gctggtcgta taggagctgt aaaaaatttc ttagatagaa tttctaataa
     9061 atagtatgta agataaggag gtgtcacaat gactaactct gtattttcga caatgcaaga
     9121 tattgagaat gttgcaaccg atattataaa atcatatgat aatgagattt atacttataa
     9181 agctgtttcc caagaagaat tggaaaaact agaaaaaagt tatgatgaaa aaagtcacga
     9241 agaattagtt tcaatagaaa gcaatttaga aatgaaacaa cagaacctta ttgatgaggt
     9301 taataaaaca atcaaggaaa atgatgcaaa tattcagtat atttcatcaa gtaggagagg
     9361 agaatttgta gaaaaaatta ttggtagggt ggtagaaaaa tatggccatt agtcagatga
     9421 aaagaatctc tctactattt tctaaaagta gtcttgatga tgttttaaaa actattcaag
     9481 aactagagtc agtgcagttc cgtgatttaa aggttcagga taactggtca gaagctctag
     9541 aaaaagatga agttgtattt ccaactattc aaatttttca tacttctaat tccaatcatg
     9601 gggttattga gggaaatgat gccttgactt atttgatgaa tcaacaacaa catttagaag
     9661 caactgtaga gaaattacaa gaatacctac cgaaagaaaa cacgtttaaa ttattgcagc
     9721 aacctccgat aactacctct tatgaagaat tagagaaatt tggtaaagct aatgttgctg
     9781 agggtgttct taaaaaagtg aatcatcaaa ttaacagagt tcatgaatta gaaagacaca
     9841 ttcaaagtaa taatgaggaa atagagcgat taataaagtg ggaaaaatta gaaattgttc
     9901 ctgcgaattt agaacaattt tctttctgta aaggaaaagt cggaacaatt ccaaggactg
     9961 aagataatcg cttatacaat agtcttttag aaaacaatat tgaagttcaa gaaatatttt
    10021 ctaatgatag agagtacggt gttgttgttt tctatcagtc tagttactct atagattttg
    10081 atgaatactt atttgaacca tttgattatt ctagaaagga attaccgaag cagcgagtag
    10141 tagatttaga tcaagaaaac atgcagttaa taactgaaaa agagaatatt atcgcatcgt
    10201 tgcaagattc aaagaaatat ttgatagatt tacaatggca aatagactat attttatcta
    10261 tctatgctcg tcaaatctct aagaataact ttttgtgcac tccgcatcta gttgca
//
LOCUS       DAVLTG010000062        10241 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLTG010000062 DAVLTG010000000
VERSION     DAVLTG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.063"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            1..389
                     /locus_tag="VYN12_001788"
                     /pseudo
     CDS             1..389
                     /locus_tag="VYN12_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            475..687
                     /locus_tag="VYN12_001789"
                     /pseudo
     CDS             475..687
                     /locus_tag="VYN12_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            587..1033
                     /locus_tag="VYN12_001790"
     CDS             587..1033
                     /locus_tag="VYN12_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1416113.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VYN12_001791"
     CDS             complement(1171..2475)
                     /gene="eno"
                     /locus_tag="VYN12_001791"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1416114.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2639..3085
                     /locus_tag="VYN12_001792"
     CDS             2639..3085
                     /locus_tag="VYN12_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1416115.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3082..3885)
                     /locus_tag="VYN12_001793"
     CDS             complement(3082..3885)
                     /locus_tag="VYN12_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1416116.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3894..4223)
                     /locus_tag="VYN12_001794"
     CDS             complement(3894..4223)
                     /locus_tag="VYN12_001794"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1416117.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4168..4539)
                     /locus_tag="VYN12_001795"
     CDS             complement(4168..4539)
                     /locus_tag="VYN12_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1416118.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VYN12_001796"
     CDS             complement(4598..6031)
                     /gene="glgA"
                     /locus_tag="VYN12_001796"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1416119.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VYN12_001797"
     CDS             complement(6028..7167)
                     /gene="glgD"
                     /locus_tag="VYN12_001797"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1416120.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7157..8299)
                     /locus_tag="VYN12_001798"
     CDS             complement(7157..8299)
                     /locus_tag="VYN12_001798"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1416121.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VYN12_001799"
     CDS             complement(8289..10217)
                     /gene="glgB"
                     /locus_tag="VYN12_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1416122.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3130 a         2265 c         1815 g         3031 t
ORIGIN      
        1 caccaagtaa aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt
       61 actgacaatc cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact
      121 accatccact atgcgctcaa agctatgggc tacactcgaa aaaaaagaac cacacctact
      181 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
      241 tagcacaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      301 tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccgcac
      361 cattggttat tatattaaaa cgaagtaaga ataggacaaa tcgatcagga cagtaaaatc
      421 taattctaac aatgttttag aagtagaggt gtactattct agtttcaatc tactatatta
      481 atggacaatg caagattcca tagaatgggg aagctagaac tcttgtgtga agagtttggg
      541 cataaacttt tacctcttcc tccctactcg cctgagtaca atcttattga gaaaacatgg
      601 gctcatatca aaaagcacct caaaagggta ttaccaagtt gcaatacctt ttatgaggct
      661 cttttgtctt gttcttgttt caattgacta tataaattgt ctaagcgaaa caaccgataa
      721 gaattggcac aaaagcgacc gtatttttgt taccaataca ggaaaaccag ttcatagttc
      781 tatcttgagc aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca
      841 tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa ataaaattcc
      901 tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta cttccatcta
      961 cacccacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata aagttatgaa
     1021 aaagattttt taaaaagttt tgtccctttt ttgtcctcta aatacaaaaa tagcccttcg
     1081 gataaaatcc gaggggctag aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg
     1141 gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga atgatttcaa
     1201 tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt ggttgtattt
     1261 agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac
     1321 tgcaatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata caacagcagt
     1381 gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag taccgatttg
     1441 gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg caaggtagtc
     1501 agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa gacgttcagt
     1561 aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag tgatgattgg
     1621 gtatttgtta accaattctt caaggtagtc gatttgttct gcagatgtac gaacagcagc
     1681 accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt agaattctga
     1741 tgaagcacag tcaaatccga taaatacgtc tttacctggt acatatccag cagcttcaat
     1801 cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag cgaatccacc
     1861 ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa gagcgtggaa
     1921 gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg gcaagatcat
     1981 gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga tgttcatcat
     2041 tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag
     2101 gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat tcgcacccaa
     2161 tttacctttg ttaggagtac cgtcaagtgc aatcatagca cggtcaatag cttgttgatc
     2221 acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt caacagcttt
     2281 ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg
     2341 ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg attcagtgta
     2401 aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc
     2461 agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc tctataatac
     2521 cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt ccttaacttt
     2581 ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata ctgttttcat
     2641 gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa taaatccgga
     2701 tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg tagatattga
     2761 cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa accttcagga
     2821 aaaagcaaag ccactatttg tgaagatttc accaactatc gaatttgata agcaagtttt
     2881 ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg aagagcatat
     2941 tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag aagaaaaaga
     3001 ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag ccaaaacatc
     3061 cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc caatattggc
     3121 agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag gttcactttt
     3181 ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta aatcttcagc
     3241 aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg caacacctat
     3301 aggcgctttc ccagcaaagc tttgactatc aagtcttcct tctccaacaa caaccaagtc
     3361 agcatctgaa actttcttat caaagttgat taagtccaag caggtatcaa ttccagacac
     3421 gatacttgcc tgagcaaagg cacacaaacc agcagcaatc cccagtcctc catcattact
     3481 ggccgtgcca ccaacaccga tataaatatc tttaatccct ttagaaatga gatggagaat
     3541 caactctcca ataccacaag tttggatttg aagtggattt cgtttctcta gcggaatttt
     3601 tccaagacca accaagtcag ctacttcaaa tagtgccagt tccccttttt gaaaatagcg
     3661 catggcttct ttttgtccaa aagggtctgt cacttggatc catttttctt ttaggtcaag
     3721 agaatgtcgg atagcatcta cagtaccttc tcccccatca ccaacagggc agaggagaca
     3781 ttctacatct gctatcgatt gttggaagcc tctttttatt gcttcagcta cctgttgagc
     3841 tgtcaagctt tccttaaacg aatccggtgc aattacaatc ttcatatttt ccctcattct
     3901 aaacagtcaa tcaaaggaag aacttctaaa aaatccctct tgtcaacatg atgtggtatt
     3961 tcttttttga gcatttcttt ggaacaaaag gcgattccta actccgccga cttcaacatt
     4021 aatagattat taaccccatc accgattgcc accgttcttt ctttagaaag ttttagtttc
     4081 tttctccatt tttccagagt ttcttttttg acctggggac ttataatttg tccaactaat
     4141 tttcctgtta aaagaccttc tttgacttca agctggttgg cagtgaaata ggcaatacca
     4201 agggattttg ctaatctctc caactattgg tgtaaatcca ccagacacca gaccaactag
     4261 gatgccattc ttttggagaa tagagatgaa ctctgggaca tttagcgata gatgaattga
     4321 gttgaagacg ttatcaaaga ccaaaatagg aagaccttcc aacaaggaca ctctttttct
     4381 taaactgctt tcaaagacca actctcctcg cattgctcga cttgtaatct gcgaaatttc
     4441 cgcctcatga cctgcctctc tccctaaaag atcaatcact tcttctagga ttaaggttcc
     4501 atctacatcc aaaacacaca agccttttac ttgagacatc agttctcctc tctaaacagc
     4561 ctaaaaatcg tatgaagtca tcatacgatt ttatctatta attaactaaa ctatggtaca
     4621 agtcaaggta tgacttgcag gctgtatccc atgagaagtc actctccata gcttgttttt
     4681 gtaggtttct ccaaatgtct ggatggtttc tatacaagtc caatgctgtt tggaaagtcc
     4741 aatttaacca ataaggagat agattgtcaa agctaaagcc agtaccgctt ccttcgattg
     4801 gattgaaagc gcgaactgta tctcgcaagc ctccaacttc atggaccaat ggcaaggttc
     4861 cataacgcat agccatcatt tgagacaagc cacacggttc aaaacgactt ggcatgagga
     4921 agaggtcaca agcagcgtag atttcctgag caagtttgac atcaaaagtg atatttgctg
     4981 atagcttgtc tgggtaaatc tgagcaaacc atgagaaagc tccttcaaag gctggatcgc
     5041 cagttcccaa aagaacaatc tgaacatctt cttgcaagat atggtgaaga ctttcgacca
     5101 ccacatcaaa acctttttga cgtgtcaaac gagaaacaat tcccaccagt ggaacgtctg
     5161 ctctaacagg caagccaact ctttcttgca attttgcctt atttttggct ttcccagaca
     5221 aatcttcctg attgaaatga tagtctaaaa gagcatccgt ctgaggatta taaagatcag
     5281 catcaatccc attcacgata ccagatactt taccagactc cattttaaga atctgatcca
     5341 aattacatcc aaactgacta gtcataattt catgagcata gctaggtgaa acggttgaaa
     5401 cacggttcgc atagagaata cctgccttca tccagttcag acagttgttc catcgaaggg
     5461 tgccatcagc gtaacgttca aggccaactc caaacaaatc acccaacatt ccttctgaaa
     5521 attgtccttg gaattctaaa ttatgaatgg ttaaaactgt ttcaatgtcc tcataggctt
     5581 gaatccaaca gtatttttcc ttcaacaaga aaggaatcat agctgtatgg tagtcatgaa
     5641 catggagaag atcaggaata aagtcaatcc tttccatagc ctcaatggca gccagttgga
     5701 aaaaggcaaa gcgttctccg tcatcaaaat caccgtaaac atgaccacgg aagaaataat
     5761 attgattgtc aataaagtag aaggttacac catttaatac tgttttctta attccacaat
     5821 actgtctacg ccaaccaacg ctcacctcaa aatgaagcac atcttcaatc tgatttccaa
     5881 atttagcctc taccatatca tagtagggta aaatcactgc aacttcgtgc ccagctttta
     5941 ccagtgattt tggaagagcg ccaatgacgt ctcccaaacc acctgttttt gaaaagggtg
     6001 caccctctgc tgctacaaat aaaattttca tgaatgaata tcctctgtta ctttagcacc
     6061 tttcttaacc acaactggat gttctgcagt tcctcgaatc acaacaccaa gctcaacttc
     6121 aacccctttg tccaagatag catattcgac ctgagcccct tctccaataa caacacgagg
     6181 gaagagcagg ctatctttaa ccaagctatc cttatggaca tgaatattac gtgatagaac
     6241 agaattagct acttgacctt caataatact accagaggca aactgagaag tgcttacctt
     6301 agatgtatta gcatagtaag ttggctcttc gtttttgacc tttgtataaa tcttttggtt
     6361 tggtgagaaa agagaataga atttttgtga ttcaagcata tcgatattcg cttgataata
     6421 agatttaaca gagtgaatat tggctagata gcccgtgtac tcgtaggcaa aagctccctc
     6481 ttttacagcc aaatcccgta aaacatagcg caatttctct ggatgttctt ttttagcttc
     6541 ttcttccaag tgttcaatca accaaggtgt atcaacgaca aagatatctg tagacatatt
     6601 gaacgtttca gctgttgact tgctatcaaa gagtttatga gaaagaacat ggtctgtttc
     6661 atctacatcc aagattgcat ttacttctga aatatctttc ttagctagtt ttttataaac
     6721 tacagtgata ggctcttttg ttgtactatg taggtggaaa acttggttca aatcaatgtt
     6781 aataagaaca tcgcagttga gggcaaccgt ttggtttgag ccagaacgtt tcaaataagt
     6841 aagaagctgt tggtagtatt cttttccaac tgtactactt tctacacggg tattgtaaat
     6901 tcctagatag taatggctaa gaagggttga taagccccac tcgcgccctg aacgaatatg
     6961 gtcaaagact gagctgatat tatcctgctg gaaaatacca aagacactac gaacacctgc
     7021 attagcaagg cttgaaagtg ggaagtcaat caaacgatat ttcccaccaa atggcaaact
     7081 tgctactgga cggtggtccg tcaatgtcga catatcgtga aaaccaactg tatttcctaa
     7141 aatggcagaa tatttatcaa tcttcatctg ttgctacccc cactacttca ttatatccta
     7201 caacttgtac ttcatctgtt ccatcaattt cgacaccgtc agaaataatc gcaccttcac
     7261 caataatggc acgtttaatc ttagctcctt gaccaatgat agctccactc atgataactg
     7321 aatcaaggac ttccgctcct tcgcgaactt gcgcgcctgt tgaaaggata gaatgtttaa
     7381 cagttccatc aacgaaacat ccgtctacaa ctaatgagtc ttccacatga gcatttgccc
     7441 cgaggaagtt tggtggtgaa atcaagtttc ttgagtaaat cttccattga cggttacgac
     7501 tatccaaggc attttctgga gaaatatact ccatgttcgc ttcccaaagt gactcaatag
     7561 taccaacatc tttccaataa ccactaaatt cataagcata aacactttca cctgactcaa
     7621 ggtaatttgg aatgacattt ttaccaaagt ctgacatgcc aaccttgctc ttttcagcag
     7681 cgactaacat attacgaagg cgttgccaat caaaaatgta gattcccata gaagcttttg
     7741 tagatttagg ttgagctggt ttttcttcaa attcaacaat acgattgtta gcatctgtgt
     7801 tcatgatacc aaaacggctt gcttctttaa gagggacgtc taaaactgct actgtcaagc
     7861 tggcattatt atccttatga gactggagca tatcatcata gtccattttg tagatgtgat
     7921 ccccagacaa aatcaagaca tactcaggat tgacactgtc gatatagtcg atattttggt
     7981 aaatagcgtg actagtcccc tcaaaccaac gatttccttc acttgcagaa taaggttgaa
     8041 gaatagagac acctgaatta ataccgtcta gtccccagct tgaaccattc ccaatatggt
     8101 tgttgagagc aagtggttga tactgtgtaa cgaccccaac attatgaatc cctgagttgg
     8161 cacagtttga tagggcaaag tcaatgatac ggtagcgccc accaaattgc acagctggtt
     8221 ttgcgatgct ttgagtgagt ttaccgagac gagttccttg cccaccagca agaatcaaag
     8281 ctaacatttc atttttcatt ttctactcct ttttggtttt tatttgtgac ggttttagta
     8341 gatttcaagc gacgtttgat tttccataca cttgctccca tagccggtag ggtaaaggtt
     8401 aaggtctgct cataatcttt ccatagtcct tcttgcgttt gaacagtttg attatgttct
     8461 ttccaaacgc ctccccactc ttccaactca gtattccata cttcttcgta aattcctgca
     8521 acgggtagtc cgattgtaaa atctttccgc tcaacaggta ccatgttaaa gatacagact
     8581 aacatttctc cctttttacc cttacgaata aaggaaagaa cactctggtc tcgattatcc
     8641 gcatcaatga tttcaatacc atcatagctg gtatcgattt cccacagaca gcgatgatct
     8701 ttgtaaaact ggtttagctg agaagtgaaa tacttcatct tagcattcat tgggtcttct
     8761 aggttagacc attccaactg ttcttcagat ttccattcta ggaattgacc gtattcgcta
     8821 cccatgaaga gcaatttctt accaggatga caaatttggt acgtatagag attgcgcaag
     8881 cctgcgaatt gattgtaacg atctccccac atcttatgca tcatactctt cttgccatga
     8941 accacttcat cgtgcgagaa tggcaagaga taattctcct tgaaaacata cataaagctg
     9001 aaagtcacca ggttaaagtc atatttacga tagatcggat cttcttcgta gaaacggagg
     9061 atatcattca tccagcccat gttccatttg tagtcaaatc ctagaccacc aatctctttc
     9121 attcccgtaa tcttggtcgc agacgaactt tcttctgcaa tcatcatcac atctggatat
     9181 tctaacttaa taacctcatt caagcgctga aggaaataat aaccttcata gttgagattt
     9241 ccgccatctt tattaggtgt ccatggagca tcatcatagt ccaaatagag catgttgcta
     9301 acagcatcca cacgaatacc atccaaatga tagacatcaa tccaatgctt aatgcaagaa
     9361 attaagaagg actggacttc attttttcca aggtcaaaat taagggcacc ccaaccatgg
     9421 ttatgagcct tattatggtc ttggtattca aaagtcggtg tcccatcata ataggctaag
     9481 gcatcatcgt tgatggtaaa gtgacctggt acccagtcca caataacccc aatattatgg
     9541 gtatgacact cctcgacaaa atcttgaaac tcctctggtc ggccataagc atgctctaaa
     9601 gcgaagtaac ccataagctg atacccccaa ctcaagccca aaggatggga catcaagggc
     9661 ataaactcaa tatgagtata gttcatttca acgagataag gaatgagttc atccttgagc
     9721 tgggcaaaac tataaggact gccatcagaa tttcttttcc atgatccagc gtgaacttca
     9781 taaatattga caggacgctc ttcaaagccc caacgttttc ttcgtgccag ccaaagtcca
     9841 tccttccatt tcttctcacg aagctctgtt aagattgccc ctgttcctgg acgagcctca
     9901 tacctgacag caaaagggtc aatcttcatc agttgatgac cattttgacg tgtgacatga
     9961 tatttgtaaa tatgcccttc ttgagccata ttggtaaaga cttcccagac cccaaaatca
    10021 tttcttacca ttggaatctg attttcaatc cagttggtaa aatcaccaac caagtgaaca
    10081 gcctgagcat taggtgccca aacacggaag gtatagccat gctctccatt tagttcttcc
    10141 ctatgtgctc ctagataatg ttggagataa aaattttcac ccgtcataaa ggtttttaat
    10201 gcttctctat tatccatata ctcctcttct cctgtaagcg t
//
LOCUS       DAVLTG010000063         9670 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLTG010000063 DAVLTG010000000
VERSION     DAVLTG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.064"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            190..285
                     /locus_tag="VYN12_001800"
                     /pseudo
     CDS             190..285
                     /locus_tag="VYN12_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(538..1158)
                     /locus_tag="VYN12_001801"
     CDS             complement(538..1158)
                     /locus_tag="VYN12_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1416123.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1158..1640)
                     /locus_tag="VYN12_001802"
     CDS             complement(1158..1640)
                     /locus_tag="VYN12_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1416124.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1640..2482)
                     /locus_tag="VYN12_001803"
     CDS             complement(1640..2482)
                     /locus_tag="VYN12_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1416125.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2577..3365)
                     /locus_tag="VYN12_001804"
     CDS             complement(2577..3365)
                     /locus_tag="VYN12_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1416126.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQALK
                     HLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDKAYKS
                     HITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTMSNMN
                     EGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLESSPKT
                     DLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3509..4888
                     /gene="glmU"
                     /locus_tag="VYN12_001805"
     CDS             3509..4888
                     /gene="glmU"
                     /locus_tag="VYN12_001805"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1416127.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLTGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4898..5443
                     /locus_tag="VYN12_001806"
     CDS             4898..5443
                     /locus_tag="VYN12_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1416128.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5455..5769
                     /locus_tag="VYN12_001807"
     CDS             5455..5769
                     /locus_tag="VYN12_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1416129.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5786..6478
                     /locus_tag="VYN12_001808"
     CDS             5786..6478
                     /locus_tag="VYN12_001808"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1416130.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6555..7046
                     /gene="rocS"
                     /locus_tag="VYN12_001809"
     CDS             6555..7046
                     /gene="rocS"
                     /locus_tag="VYN12_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1416131.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7144..7734
                     /locus_tag="VYN12_001810"
     CDS             7144..7734
                     /locus_tag="VYN12_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1416132.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7743..9506
                     /locus_tag="VYN12_001811"
     CDS             7743..9506
                     /locus_tag="VYN12_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1416133.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2996 a         1684 c         2059 g         2931 t
ORIGIN      
        1 aagacttttt gaccagcctc atttttttaa cttgatactc agtgaaaagc aaagattaaa
       61 ctagaaagct agccgcaggc tgctcaaaga acagctttga ggttgcagat aaaacttgtg
      121 aggtaaccaa catatataat gtgaagctga cgtggtttga atagatttta gaagggtatg
      181 agtctggaag ttttaatgga taatgcaaga ttccatagaa tgggtaagct agagttctta
      241 tgtgaagagt ttgggcataa acttttacct tttcctccct actcatctta gtatagaaaa
      301 gtgaatctaa aatagtacat aactgcttct aaaacattct tataaattga tttaaattct
      361 caaatcatat tattcagttc ttatttcatt ttgctctaca atcctgttga gaagacacgt
      421 gttcatatca aaaaggtatt ggcaagttgc aatacctttt tacaaggttc ttttgtctta
      481 tttttgtttc aactgactat atctcctatg gttctagttc agaaggctag gctataatta
      541 tgattgataa gaagtatcat tccaagtatt gagagtgaat gtttcaaaat catgggtttc
      601 tataatggtc aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata
      661 gcctaggaga gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg
      721 ctcagctgga ctatctttta atgatttgat aaattggatg gtccgctgag ttgtactata
      781 gagggattcg gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg
      841 gatttgttgc gggtaaatag cttccagggt tgcaattttc aaaccttcta acttcccaag
      901 ttgccattca cggagattag gaacgatttc taaagaacag ggggtataga gttgactttg
      961 gataatctca gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg
     1021 aatttccttg agatactgac caagtcgttt tagggtttca atggattcag gaagaagagg
     1081 agaatcacca ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg
     1141 gacaaagtag agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca
     1201 aagctagcca agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca
     1261 atcatttgat ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga
     1321 cgaattccga caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt
     1381 tgtggaatca tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag
     1441 tgctgagtga tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag
     1501 gttttgaaaa tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt
     1561 tgaatcccct gatgagggat agctgcttta gataggattt gttccaccaa tgtttttttg
     1621 attttaactt tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa
     1681 gccagattcc cagcgcaaag aagaaggcga tgatgacata accgacaagt gaaagtcctg
     1741 tgtattggat actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata
     1801 ggacgatacc gatgatgaaa tgatagacgc gtgagtggta gttgtttaag gcataatcca
     1861 tcaattttga aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc
     1921 ccaagaaatc aaaagtttta aaaccagtca acataggagc atatagtccc aaaatcaaaa
     1981 gtaaatttga tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta
     2041 ggacgaagtt aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc
     2101 ctaatccaga aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag
     2161 attctcgagt tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc
     2221 tccataatac aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc
     2281 cgattcccag aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt
     2341 ctttaaaggg atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta
     2401 gaacccctcc ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa
     2461 cgcgtgctaa ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta
     2521 ctatattgta tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa
     2581 ggttttaaaa aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg
     2641 atatctaaat cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca
     2701 taatctaaat cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga
     2761 atccaaacag aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca
     2821 acgtagatgc cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca
     2881 ccttcgttca tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg
     2941 taaggagagg cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt
     3001 ccagctacat aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga
     3061 ctcttatagg ccttgtctat tccattgata aatgaagcat cattttcttt tgttgtttga
     3121 gcaccactgt gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg
     3181 atttcctcag gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa
     3241 gcctgtgcta tattggattt tgttttaaac gattggctgt cattaagtgg gcgattgatg
     3301 attaaaatga acatcataat cccaaaaaaa ctaaataaaa taagtggatg aatttgtttt
     3361 ctcatatctt ataagtctac cctaaaaatc aaaaaaaatc aaaaaaatgg gttaaggaag
     3421 agactttaga gcattttttc attcaagagt gcggaatgat ttgaaatatg gtataataaa
     3481 agggaatttc tacagaaaag agaagattat gtcaaatttt gccattattt tagcagcggg
     3541 taaagggact cgcatgaaat ctgatttgcc aaaagttttg cacaaggttg cgggtatttc
     3601 tatgttggaa catgttttcc gtagtgtggg agctatccaa cctgaaaaga cagtaacagt
     3661 tgtaggacac aaggcagaat tggttgagga ggtcttgact ggacagacag aatttgtgac
     3721 tcaatctgaa cagttgggaa ctggtcatgc agttatgatg acagaaccta tcttagaagg
     3781 tttgtcagga cacaccttgg tcattgcagg agatactcct ttaatcactg gtgaaagctt
     3841 gaaaaacttg attgatttcc atatcaatca taaaaatgtg gccactatct tgactgctga
     3901 aacggataat ccttttggct atggacgaat tgttcgtaat gacaatgctg aggttcttcg
     3961 tattgttgag cagaaggatg ctacagattt tgaaaagcaa atcaaggaaa tcaacactgg
     4021 aacatacgtc tttgacaacg agcgtttgtt tgaggctttg aaaaatatca ataccaataa
     4081 cgctcaaggc gaatactata ttacagacgt cattggtatt ttccgtgaaa ctggtgaaaa
     4141 agttggcgct tatactttga aagattttga tgaaagtctt ggggtaaatg accgtgtggc
     4201 gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat cataaacaca tggtcaacgg
     4261 tgttagcttt gtcaatccag aagcaactta tatcgatatt gatgttgaga ttgctccgga
     4321 agttcaaatc gaagccaatg ttatcttgaa agggcaaacg aaaattggtg ctgagactgt
     4381 tttgacaaac ggtacttatg tagtggacag cactatcgga gcaggagcgg tcattaccaa
     4441 ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca gtcggtcctt atgctcacat
     4501 tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt aactttgttg aggtgaaagg
     4561 atcttcaatc ggtgagaata ccaaggctgg tcatttgact tatatcggaa actgtgaagt
     4621 gggaagcaac gttaatttcg gtgctggaac tattacagtc aactatgacg gcaaaaacaa
     4681 atacaagaca gtcattggag acaatgtctt tgttggttca aattcaacca ttattgcacc
     4741 agtagaactt ggtgacaatt ccctcgttgg tgctggttca actattacta aagacgtgcc
     4801 agcagatgct attgctattg gtcgcggtcg tcagatcaat aaagacgaat atgcaacacg
     4861 tcttcctcat catcctaaga accagtagga gcctatcatg gagtttgaag aaaaaacgct
     4921 tagccgaaaa gaaatctatc aaggaccaat atttaaactg gtccaagatc aggttgaatt
     4981 accagaaggc aagggaactg cccaacggga tttgattttc cacaatgggg ctgtctgtgt
     5041 tttagcagta acggatgaac aaaaacttat cttggtcaag cagtaccgca aagctatcga
     5101 ggcagtctct tacgaaattc cagccggaaa attggaggta ggagaaaaca cagcccctgt
     5161 cgcagctgcc cttcgtgaat tagaggaaga aacagcctat acagggaaat tagaactctt
     5221 gtacgatttt tattcagcta ttggcttttg taatgagaag ttaaaactat atttagcaag
     5281 cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag gatgaaacct tggaagtcct
     5341 tgaagtgagc ttagaagaag cgaaagaatt aatccaatca ggtcatatct gtgatgccaa
     5401 gacaattatg gctgttcagt attgggagtt gcagaaaaaa tagaggaggt cagtatgggt
     5461 aaatctttat taacggatga aatgattgaa agagctaata gaggcgaaaa aatttcaggt
     5521 cctcctttgc tagatgataa tgaggagact aagattttac caacctcttc ttcccgtttt
     5581 ggttatgcca atcctaagga tcatggtttt agccaggaaa ccttgaaaat tcaggtcgaa
     5641 ccatctattc ataaaagccg tcgcattgaa aataccaaga gaaatgtctt caattctaag
     5701 ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt tgcttgtttt agcaatgaaa
     5761 cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt attgctgcta tgccagaaga
     5821 actggcttat ctggtccagc atttagataa tacccaggag caagttgttt tggggaatac
     5881 ctatcataca ggaaccattg cttctcatga agtcgttctt gtagaaagtg gaattggtaa
     5941 ggtcatgtct gctatgagtg tggcgatttt ggctgatcat ttccaggtgg atgcccttat
     6001 taatacgggt tcagctgggg cagtagcaga aggtatcgct gttggggatg tcgtgattgc
     6061 tgacaaatta gcctatcatg acgtggatgt cacagctttt ggctatgctt atggacaaat
     6121 ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt gttgctcaaa tccaagagag
     6181 tttatctcaa ttggaccaaa actggcatct tggtttgatt gctacaggag atagttttgt
     6241 tgcaggaaat gacaagatag aagcgattaa gtcccatttc ccagaagttt tagccgtgga
     6301 gatggagggg gcagctattg ctcaagcagc gcatgccctc aatctcccag tcttagtcat
     6361 cagagctatg agtgacaatg ccaaccatga agcaaacatc ttttttgatg agtttattat
     6421 cgaagctgga cgtcgctctg cccaagtctt gttgaccttt ttgaaggctt tagattaagc
     6481 ggaaatttga cagtttttct agcttatgat aagatttaag taaagaaaag ctagaaaacg
     6541 tttcagagga tattatgagt attgaaatga ccgtcagtga gattgcagag gtcttaggat
     6601 tatctcgcca agcaatcaat aaccgtgtca aagaattacc agaagaagac acagataaaa
     6661 atgacaaagg ggtaacagtt gttaccagaa gtggcttgat taagctagaa gaaatctata
     6721 aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt caaacaacgt gaactgatgg
     6781 agattctagt ggatgagaag aatgcagaaa ttcttcgtct ttatgaacaa ttaaaagcca
     6841 aggatcgtca gttatcagaa aaagacgagc agatgcgtat caaagaccgt cagattgctg
     6901 aaaaagacaa acaattagat cagcaacaac aattgaccct tcaagccatg aaggatcaag
     6961 aaaatcttaa gctagagctg gaccaagcaa aagaagaagt ccaatccact aagaaaggct
     7021 tttttgctcg tttatttgga ggataatcaa ggagctgttt aggttaaatg ctaacctgat
     7081 ggcttctttt gtttgtgaat agtatagttg attagaacag agacagtaga ggagaggtac
     7141 agaatggaac gattagaaga ttacattgct tttgacttag aatttaatca gcacgaagga
     7201 caaacacact tgattcaagt atcggcagtg cgttttagag atggtcggga aatcgatgcc
     7261 tatgattcct atgttcatac cagcgtccct ctaaaaagct ttatcaatgg tttgaccggg
     7321 attacagctg agaccttaaa agatgctcct ccagttgaga aagtcttaga agaattccaa
     7381 gagtttgtgg gttctttgct gatgataggc tacaatgctg ctaaaagtga tttacctatt
     7441 ttagcagagc atggtttaga ctatagccaa cagtacaagg tggatttgta tgatgaagct
     7501 tttgaacgtc ggagttcaga tttacatggt attgccaatc tcaaattgca aactgttgcc
     7561 tcatttcttg gatttcaagg tcagtctcat aatagtttag aggatgctcg gatgacggcg
     7621 cgtgtttacg aatccttctt agagtcggat caagctaggg aattgttaga gacagaaagt
     7681 agcttatcaa acaatccttt tggtggcttg gacttgtctc aattatttga ctaggagtgc
     7741 ctatgaaacc tgaaaaacct aaaaaattgg gtcttaaaca gatttacctc aatcttgata
     7801 aaatcctctt tctatttttc ttgattttta tgatagtgga gtatttgtgg gtaccattca
     7861 attcatggtt ggctagcttc ttattagatc agacaggtta tctttttatt tcctataaca
     7921 atgtcttagc catccttact cattctccat tgattagtct agctttttta gccttgattg
     7981 taattaacct tctggttgct tattttcaaa taggactcct ctttattggt gctcgtcatc
     8041 tcctctataa tgaaaagcga aggctaattg agtatatccg caaggttttc catgaaagtt
     8101 ttggatttat gaaaaagcta acttgcgcta aagccttgtt tatctttttc tatatagcta
     8161 tgctttttcc ttttatacgg aaaatgctga agatttatta tcttaataaa atcgtcattc
     8221 cagagtttat ccaagcttat ttagaagata aatattggat gtggtggctg agcatcctac
     8281 ttctatctct tatctttctc tatgtctctg tcagattgat gtttgccctt ccgaagattg
     8341 tatatgatca gctgactgtt cgagaagcag tgatgtttag cttggagaaa accaagaaga
     8401 gagttacttt ttatgcttgg aatttatttt acatcttgct caaagcacat ttattatttt
     8461 atcttccttt gattccttta ttattggctc aaactttggt agatgatatc actcagagag
     8521 agtctctgat tcttggtatt ttgaattttg tcgtgattaa aaatctctat tatatggctc
     8581 tgacttattt tttggttaaa tttgtttcat ttttgacagg aaaggagctg gatatgcttc
     8641 ctaggagaga aaaagatcac atcgtgcgat ggggtgtcat gacttgtgcc agtcttttct
     8701 ttgccttaga aggttatatt tatctggagg ctcccatggt tcatctacct caacttattt
     8761 ctcaccgagg ggtttccaat gcaaatggga ttcaaaatac agtagagtcc ttggaaacta
     8821 cagcacaact caaaccagac ttggtggaga cggacgtgca ggaaacaaaa gatgggcagt
     8881 ttgtcatgat gcatgatgct aacttgaaaa atctagcagg tatcaataaa agtcctcaag
     8941 acttaaactt ggaggagctt aaagggattg atatttttga aaatggctac cagactaaaa
     9001 tttcaagctt tgaagattat ctcagtcgag ccaacgaact tggtcaaaaa ttactaattg
     9061 aaattaaaac cagtaaaaaa gatagtccag acatgatgaa ccgcttttta gcccgttatg
     9121 ctgcaaagct caagatttat ggacatcaaa tccagtcttt agactaccat gttgtcgaaa
     9181 aagtaagaca gtatgatgcc gaactgccag tttatttcat catgccctac aattctgtct
     9241 ttcctaaaac aagagcgaca ggatatacta tggagtactc aaccttggat gaatattttg
     9301 taagcaaact atggacaacg gatcagaaac tttatgtctg gactgtcaat gattcagaag
     9361 ctatcagcaa atctcttcac ttaggagtag atggagtgat tacagatgat ttggaaaaag
     9421 ttcagcggga aatagaagta gcccaagaag atccagaata tacggatttg ctcttgaaaa
     9481 aagcattgga attctttgaa ttttagtaat aaaaaagagg aacggttgtt cctcccatga
     9541 taggtaagta ttcttgtgaa tgcttgcttt tttgtggttg caatccgttt acgagaattg
     9601 tttgtattgt tcttgtttca atttacttta tagtgctttg aagttggaat gctacactat
     9661 aacttctaaa
//
LOCUS       DAVLTG010000064         9327 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLTG010000064 DAVLTG010000000
VERSION     DAVLTG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.065"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            269..1078
                     /locus_tag="VYN12_001812"
     CDS             269..1078
                     /locus_tag="VYN12_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1416134.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(1259..2134)
                     /gene="aguB"
                     /locus_tag="VYN12_001813"
     CDS             complement(1259..2134)
                     /gene="aguB"
                     /locus_tag="VYN12_001813"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1416135.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(2144..3229)
                     /gene="aguA"
                     /locus_tag="VYN12_001814"
     CDS             complement(2144..3229)
                     /gene="aguA"
                     /locus_tag="VYN12_001814"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1416136.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPVVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(3226..4353)
                     /gene="nspC"
                     /locus_tag="VYN12_001815"
     CDS             complement(3226..4353)
                     /gene="nspC"
                     /locus_tag="VYN12_001815"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1416137.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(4353..5612)
                     /locus_tag="VYN12_001816"
     CDS             complement(4353..5612)
                     /locus_tag="VYN12_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1416138.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(5609..6469)
                     /gene="speE"
                     /locus_tag="VYN12_001817"
     CDS             complement(5609..6469)
                     /gene="speE"
                     /locus_tag="VYN12_001817"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1416139.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            6850..7440
                     /locus_tag="VYN12_001818"
     CDS             6850..7440
                     /locus_tag="VYN12_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1416140.1"
                     /translation="MSFRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIK
                     EFAKSLSLRKTKTNKKDAHGIALKLLSDPNREQFQHDNRQVELKILTRHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTAS
                     NSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
     gene            complement(7406..8881)
                     /locus_tag="VYN12_001819"
     CDS             complement(7406..8881)
                     /locus_tag="VYN12_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1416141.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSARKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         2708 a         2083 c         1789 g         2747 t
ORIGIN      
        1 atatttcctc cattattctt cagattagtt gagtaatctg atactcatac ctacttacaa
       61 aaaaactatt atattaagtt ggttttttaa tttgtctagt tgcaacattg acaaacatag
      121 tatagcatat ctttgccaaa tatcctcttc aaatcatgaa ttgtcatcaa aacatcttaa
      181 actataaaat caattagtct caagctttct atcaatttct tctccaaaat atgctataat
      241 actaccaaaa gataaagaag gaagacctat gattaaacta ctagccttgg atatggatgg
      301 aaccctcctc aatgaagcca aggaaatccc acaagctcac attactgcta ttcacaaagc
      361 cattgaaaaa ggtgtcaaac tggttctctg tacgggtcgc ccccttttcg gtgtcctccc
      421 ctactacaaa aaactggggc ttgacctcca gaacgaatat gttattgtta acaacggttg
      481 ttcaactcac caaaccagtg attggggtct agttgactgg aaagaactga gtccagctga
      541 catcgaatac ctctatgacc ttgctgaaaa gagtgatgtt cagttgacac tttttgacga
      601 gtcacattat tttgttctcg gtggcaagcc caatcaagtt attgaaaatg atgctaaact
      661 agtattttca gacctgactg aaatttctct tgaggaagcg actagtggaa agttccggat
      721 gttccaaggt atgtttttag gaacaaaaga acaaacagac gattttgagc agcgttttgc
      781 tgaagagctt tgccaacgat tcagtggagt tcgttcgcag cctgtcattt atgaagcaat
      841 gccacttgga acgacaaagg ctactgctct ttcacgacta gctgagattt tgaagattga
      901 ttcctcagag attatggcca tgggcgatgc taataacgat atcgaaatgc tccagtttgc
      961 agggcttggg attgcaatgg gaaatgccag cgattatgtc aaatctcttg cggatgccgt
     1021 tacctcaagc aacgaagaag acggcgttgc gcgtgctatt gagaaatata ttctataaaa
     1081 aagaaaagca aatagacaga agttactgct atttgctttt ttgctaatat tttaaaatac
     1141 ggactaatca atagacaaga atagcgaatc ataaaaatcg atttactaga tgccatagta
     1201 tcttatagtt gctaataaga agttagtcta gcagaatgaa tctctcattt ctcccacact
     1261 aatctgtaat ttgtctatac atttctggtc ttctatctcg aaacaagccc cagtttaggc
     1321 gttcacttgc tcccttgtct aggtcataag tagctaacag aacagcttct tcttgtcttt
     1381 cagctcgttc tagaatagct cctgtttcat ccgtcataaa ggaggaaccg tagaagtcaa
     1441 gactggaact ctgtccgcca ttttcctcac taggagtaac ctcctctaaa ccataacgat
     1501 tggctgcgat gactggaaca atattcgctg ctgcgtgccc ttgcatagta cgttgccagt
     1561 gaccacaact atctgtatcc aaaattggct ctgaaccgat agctgtagga taaaagagca
     1621 attcagcacc attcaatgca agacagcgcg ctgtttcagg gaaccattga tcccaacaga
     1681 taccgatacc aatcttagca tagcgagtat tccagacctt gaaaccagtg ttaccaggcg
     1741 tgaaatagaa tttttcttga taataatggt catctggtat gtgggtcttt cgataaacgc
     1801 ccagcacttc cccatctgca tcaatgacgg caatagagtt atacaagaca ttaccatctt
     1861 tttcatagaa actgattggt aaaacaactt gtagttcctt agcaatcacc ttaaaatgct
     1921 gaatggcagt attttccgct acagattggg catactggta gtagtcatac tgacgttcct
     1981 gacagaaata gggatgttca aacaactcgg gcaagagaat aatttgggct ccttgctcag
     2041 cagcctgacg tactaaacgc tctgcggttt ggatatttgt tgccacatcc ttagcgcatt
     2101 gcatctgaat ggttgcaact cttacatttc tcatcttttt ctcctattct ggaatttgtt
     2161 gggtgataca gtggatatta ccaccaccta agagaatatc tctggctggt attccgacaa
     2221 ctttacggtc tgggaaacac ttgctgagga tatctatggc cacttggtcg tttacatcct
     2281 caaactgtgg aaccaagaca gccttgttgg cgatataaaa gtttacgtag gaagctgcta
     2341 gtcgttcacc tgcgtatcgc tcttcttctc cttcttcata gatgtagcct ggcaaatctt
     2401 cttctgtcac aacttgtcga actacaggga taggcaattt atgaatggtg aagtgacaac
     2461 cttttgcatc tgtttcctgt tctaagagtt cgagatctgc ttttgacatg gcatactggg
     2521 gatcattttc gtcatctgtc caagccaaaa caagctcagc aggaccaaca aaggcagcaa
     2581 cattatcgac gtgttcattg gtttcatcct gataaatacc ataaggaagc caaataactt
     2641 tttcagcacc aagactttct aataatgtgt tttcaatctc ctctttagtc aagttaggat
     2701 tgcgaccagg actaagcaag caactttcag ttacgagaat agttccttga ccatcgctat
     2761 ggattgcgcc tccttccagt acaaaaggtt tagcatcata gacaggcctt tccaaagcct
     2821 cagcaaaacg actggctact tggtcatcct cttcataatc ttgataaaga ccatcatagg
     2881 tgcctcccca agcattgaag gcccaatcca cggctaattt cttaccttta tcattgacga
     2941 gaatggttgg gccagtatca cgcgcccagg catcattggt gggaatgtct aaataaacaa
     3001 ccttgtctcc aagataggat tgggcttcag atagataggc ctgctccacc aaaagataga
     3061 ctctttcccc ttctgctatg gtctcgatga tctgagtaaa tgctctttta gcagcctttc
     3121 cttgaaaagg ccatgatcct ggtcgagtcg gccatatcat gagggtacca tgatggggtt
     3181 cgtactctgc tggcatgtga tagcctaatt tttttggact gtccatcatg ataatctccc
     3241 tttaaagtct tgatagccaa aagctttgag taagctacag tctccctgtt cgtccatgag
     3301 atagagactt ggcaatccaa taccattaaa ggtattattt ttgacaaaag aataaatggc
     3361 catgtcttga aaataaagtc tgtctccgat ttggactgga ttttcaaaac tataatcacc
     3421 aatcacatcg ccagtcagac aggtattaga agaaagtctg taggtatggg ctttttcctg
     3481 tgcctcaaag ccatttctca aaggtggacg atagggcatc tcaagtacat caggcatatg
     3541 gcaggtcgca gaggcgtcta aaaccaagat ttccataccg ttttctacaa tatctaatac
     3601 ctcagttgct aaataacccg cattaagcgc aatggcttca ccaggctcga tatagatttc
     3661 aagattgtaa gtttttcgga tacgcttgat ttctgaaatc agcaaatcca catcgtaacc
     3721 ttctcttgta atatgatgac caccacccat attgagccat tttacctcat gtaagtaggg
     3781 accaaattgt tcttctactg ctttcaaagt tgtttgtaaa tcatctgctc cctgctcgca
     3841 aagggtatga aaatgaagtc cgtcaaccaa atctagcaaa tcactcggaa tcttgtctat
     3901 agtaactcca aagcgagaac ctggtgcaca agggtcatag agcgcgtgat ctccttgagt
     3961 tgaacactga gggttgaggc gcaaaccaac actgacacca gcctctcgac aacgagcccc
     4021 atgcttacgc aactgtctct ctgagttaaa gacgatatgg tctgttatcc caagcaattc
     4081 ctccaagtct gcatccttga aagcaggcgc aaatacatgg acttcaccag gaaattcttc
     4141 ccttgccaat ttggcctcat agagtccact agctgtcgta cctgatagat actggctaat
     4201 caagggataa gttttgtaga gggaatatgc cttctgggca agcaagacct tgcaaccggc
     4261 ctcttcttgt acatattgta gaatgcggca attagcttct aacttggcca agtcaataac
     4321 ataggctggt gttggtactt gttctaactt cattagtcca ccatttgtgg attttcaacc
     4381 acaacccatg gcaaaccata ctcattcaaa gcttccatga atggatctgg atctaactcc
     4441 tcaaggttat acactccagc ttgtttccaa gttccgttca tgactaattt tgtcccaatc
     4501 atggctggaa ctcctgtcgt gtatgaaatt gcttgtgacc cgacttctgc atagcactct
     4561 tgatggtcgc aaacattgta gatgtagata gtcttttcaa cgccatcttt gacacctgta
     4621 aagatacatc caatattggt tttacctaca gtacgtgggc caaggctagc aggatctgga
     4681 agcaaggctt tcaaaaattg aattggaaca atttcttggc cgttaaagtt aatggtatcc
     4741 gtacgaagga gtccaacatt ttcaagacat ttcatgtgcg tcaagtaaga ttgaccaaaa
     4801 gtcataaaga aacgaatgcg tttgacacct ggaatgttct tggccaatga ttcgatttct
     4861 tcatggtgaa ggagatacat atctttttgt ccaacttgag ggaaatcata ctcacgcttg
     4921 atagacatag cttcgacttc gacccatttc ccatcttccc agtaagaacc tggcgcagaa
     4981 acctcacgga gattaatttc tggattaaag ttggttgcaa atggataacc gtggtcaccg
     5041 ccattacagt ctaaaatgtc gatataatgg atttcatcaa aatagtgttt gagggcataa
     5101 gctgaaaaga cactagttac acctgggtca aaaccagaac caagaagagc agtcaagcct
     5161 gcttctttga atttctcttg ataagcccac tgccatgagt agtcaaagta ggctgtaaaa
     5221 ccaagttcct tacaacgttt ttcgtagata gcacgccact cagggtcttc tgtgtcttct
     5281 gcttcgtagt tggctgtatc gatatagtga acacctgttg ccaaacaagc atccataatg
     5341 gttaaatctt gataaggcag agctacattc aaaacagctt ctggtttgta gctttcaatc
     5401 agggcaatca cttcttcaac cttgtcagca tcaagtgctg cagtttcaat tttagtactt
     5461 gttttgcctt ctagcttcgc tttcaagtca tcgcattttg acttggtacg gctagcaatc
     5521 ataatctctg taaatgtttc gctatcttga caaatctttg aaatagcaac ttgggcaacg
     5581 cccccacaac caataactag taaacgactc atttttttcc ttcctcttct tctaaaatgt
     5641 cctcaacata cttgggcaac ataaaggatc ccacgtgtaa gtttgcagtg tagtattctg
     5701 tgaaaagctg gcgttttttc caaccttcct tgtcaaaatc tttgacaggg tggtattttt
     5761 tcgatgcaaa tccaaacaac caatagccag ctgggctagt tggaatatgg gcctgataaa
     5821 cccgactgat tggaaaggct tgattgacct tgcggtgcat gcttcggcag gccgactcat
     5881 cctcgtcaaa gaagggactc ccatgctggt aaatcatgat gccgtcttcc ttcagagctc
     5941 gataactatt gccgtagaat tccttggtaa agagtccttc cgtatggcca aatggatctg
     6001 tcgcatcgtt gatgataata tcgtaatcat cttcgcagtt tcgcaaaaag cgtagcccat
     6061 tttggtagta aatggtaaca cgaggatcat ctagccctgc agcaaagtct gggaaatact
     6121 cacgacagac ctcgaccaac atctcatccg gttccacgat atcgatttgt tccagttcag
     6181 gatagagtgt taatacttgg gcaacaccgc cgtcaccacc cccaataacc aatactttct
     6241 ttggatttgg gtggacagcc atgggaacgt ggacggtcat ttcattgtag acgaaatcat
     6301 ccgcatctga gaacaagaca tggccattta aaatcagtat tttcccaaaa gctggcgtat
     6361 ccaagacttc gatatcctgc cattcacttt ttccagcgta aagttgcttg gctgttctca
     6421 gagacaattt gacatctgga gtatgaactt cagaaaacca taaatccatc tatttctcct
     6481 tatattatat ttagcgcagt tagctactgc caaagcccaa gtggtatact tggaataagt
     6541 cactgtggat tagttcattt cctccaatcg cttgacgatt tccgaaaggc tctaaccaca
     6601 gctttttgtt tcaattggta atgagtttga taacgcatag acgttttatc tcgtctaagg
     6661 taacaaggca aaaagttcgt ggataaccaa gtagacttga aatactatat ctggaggtac
     6721 tcccatgctt tatgtaggta ttgatgtcgc taaaaataaa cacgatgtta cagccttgaa
     6781 tgttcgagga aaactgttct taaaccactc actttttcaa ataataaagc tggttttgaa
     6841 ctcttagatc tgtcttttcg acagctcaac caagactgtc tcatcgctct tgaagatact
     6901 ggacattatg cctttaatct actgaacttc ctgcatgaac aaggatataa agtttacacc
     6961 tacactcctt tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa gactaaaacg
     7021 aataagaaag acgctcatgg catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa
     7081 tttcaacacg ataatcggca agtagaacta aaaatactga ctagacatat tcatcgtctc
     7141 aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat catctttcct
     7201 gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt gacacgctac
     7261 cctaatcctc agaaaaggat tgaggcagga tttgataagc tgatagaaat taagcgattg
     7321 accgcttcta attcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt
     7381 gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc tttctcttaa
     7441 taacgttgat atgattgacc tctggatctt ccgtcccttg gagggagcaa ccacgttcct
     7501 tggcgaattg gatatagtcg acaatttctc gtgtaatgcg ttcaccagga gccaagatag
     7561 gaatccctgg aggatagcac atgacaaatt ctccacagac ctgtccaaca gaatcatcca
     7621 aagttaaact ttttcttgct gaatagaagg cttcttgcgg agacagcact aactcgggct
     7681 gaatatattc tcctgctatc aaatcttttc catctcttga atagagtctc ttaatatcag
     7741 ccagagcacc aaccaagcgc tcgatgtctt ggatgcggtc gccgatagaa atataggcca
     7801 agatattgcc gatatcacca aactcgatct gaatgtcgta ttcgtctcgc aagaggtcat
     7861 aaacctcgat acctgttaag ccaataccct gagtgtaaac tgacagctta gttacgtcaa
     7921 aatcgcaaac cgaaacaccg tctattaatt cttttgagta ggcatagtag ccaccgatag
     7981 cattgatttc acggcgggca tactcagata gctcaatgac tttctcaaac gactctttac
     8041 cacgaagggc caagttgcga cgtgaaatat ccaaactagc catcaacaag taagaggcag
     8101 atgtagactg ggtcaggttt ataatctgac gaacgtactc gggattcatc tgctccccga
     8161 ttaaaagaag cgaactttgt gtcaaactcc caccagactt atgcatggaa actgctgcca
     8221 tatcagctcc tgcatccata gcagaaattg gaagtttacc agtgaaatgc aaatgcgctc
     8281 catgggcttc atctactaaa accatcatgc cagcttcatg agccatttct gtcaacccct
     8341 ttaggtctga acagatgccg tagtaagtag gattgttgat taggatagcc ttagcatctg
     8401 gatggtcctt tatggcctgt gctactcggt cattttcaag acctaaagcg ataccaatct
     8461 taggatctac actcatctcg atatagatgg gaatggcacc acatagaacc aacgcattga
     8521 tagcagattt atggacattt cgtggcagaa taatcttatc tcctgccttg caggttgcca
     8581 gaatcatagt ctgcaccgat gaagttgttc caccaatcat tagaaaggca tggctagctc
     8641 caaaagcatc tgcagccagc tcctctgcat cacgaataat cgaaatagga tggcctaaat
     8701 tatccaaggg tttcatcgaa ttgacatcaa tgcctacaca tttttctcct aagagttcga
     8761 caagttctgg atttccccgt ccacgcttgt gacctggaac atcaaaggga acaatccttt
     8821 tcttgcgtaa cttcaccaag gcctcataaa ttggggcttg gttttgatct aactctttca
     8881 aaacatactc ctttcaatat ttttaggacc ttatgaaaac taaggaacta aaggttgact
     8941 catgaaaaaa gagcaggttt tcacctgctc tgcaatcttc tgacgtgttt attttggttt
     9001 ctgttgagta tgtctgttcc cgatgtttcc taactctcta gtagcaaata ttacgtactt
     9061 tattgatcgt ttcacaagat gacgtgtgct ttcaccacac taaaaattta tgaattagga
     9121 caagtgtcct aacatcaact tataaaagta ggcttttaac cctatcaata atgtggcttt
     9181 tcaaccacgc ttcggcattc aaccctgcct gtccgtaggc attttttact cgggtttata
     9241 tttgctagaa aacatcatct cattttctaa gctttattac tatatcatgt ttttaagaac
     9301 ttgtaaagta ttttttgata aaaaaca
//
LOCUS       DAVLTG010000065         9298 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLTG010000065 DAVLTG010000000
VERSION     DAVLTG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.066"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            454..1497
                     /locus_tag="VYN12_001820"
     CDS             454..1497
                     /locus_tag="VYN12_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1416142.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1664..3751
                     /gene="topA"
                     /locus_tag="VYN12_001821"
     CDS             1664..3751
                     /gene="topA"
                     /locus_tag="VYN12_001821"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1416143.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3857..4216
                     /locus_tag="VYN12_001822"
     CDS             3857..4216
                     /locus_tag="VYN12_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1416144.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4309..4941
                     /locus_tag="VYN12_001823"
     CDS             4309..4941
                     /locus_tag="VYN12_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1416145.1"
                     /translation="MIYEFCAENMTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            4985..5641
                     /locus_tag="VYN12_001824"
     CDS             4985..5641
                     /locus_tag="VYN12_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1416146.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5660..6292
                     /locus_tag="VYN12_001825"
                     /pseudo
     CDS             5660..6292
                     /locus_tag="VYN12_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6320..6754
                     /locus_tag="VYN12_001826"
     CDS             6320..6754
                     /locus_tag="VYN12_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV1416147.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGCSVSYHDMPSV"
     gene            6766..7803
                     /gene="leuB"
                     /locus_tag="VYN12_001827"
     CDS             6766..7803
                     /gene="leuB"
                     /locus_tag="VYN12_001827"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV1416148.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVSMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7800..8069
                     /locus_tag="VYN12_001828"
     CDS             7800..8069
                     /locus_tag="VYN12_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1416149.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8073..8432
                     /gene="leuD"
                     /locus_tag="VYN12_001829"
     CDS             8073..8432
                     /gene="leuD"
                     /locus_tag="VYN12_001829"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1416150.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8594..9217
                     /locus_tag="VYN12_001830"
                     /pseudo
     CDS             8594..9217
                     /locus_tag="VYN12_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         2870 a         1643 c         2064 g         2721 t
ORIGIN      
        1 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
       61 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
      121 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
      181 taaaaaatgg tctaaaatag atgatgatac ttttcgaaaa tctttttacg tcagctcagc
      241 tttgccttgc tgtgttttga gcaagctacg gttagcttcc gagtttgatt ttcatttact
      301 agaaatgaaa ctgatgagag atatcagtag acatttgagt caggatatta tggaaaatga
      361 taaaaagagc tcgtgagatt ggcatatcag actactaaag tattgagttt gttaggattt
      421 tagcgactag ttagctggga aaggaagata tttgtgacaa ataataaact gtattcgttg
      481 atagaattta gaaataaaat atatgaagaa ttagaacttt ccagaagtga tttagcgatt
      541 ttactatgtg ccatgcttat cgcctctatc ggattaaata tggattcgac tcccgtgatt
      601 attggagcca tgttaatctc tcctttgatg acacctattc tgggagtggg gctctctcta
      661 gctatatttg attttaaatt gttaagaaaa tcttttaaaa tattagctat tcaaattctt
      721 gccagtctaa tagcttcaac actttatttt tatctttctc ccatttcgta tgctagttcg
      781 gagattgttg ctagaacctc tccgactatt tgggatgttc tcattgcttt tgtaggaggg
      841 atagcaggta ttattggtgc taggaaaaaa gagaccaata atattgttcc tggtgttgct
      901 attgcaaccg ccttgatgcc tcctctttgt acagtaggtt atgctattgc ttctgctaat
      961 ctaaaattta tcataggctc ctcttaccta ttcctcatca attgtagctt tattgtcatt
     1021 gcgacttata taggtgttag gttgatgatg gttaagaaac attattttaa agataatgaa
     1081 gaagactcta aaatgcgtag gattttgctt ctagttgctg ttttgctgat gattccgagt
     1141 ttcatctctg caacgacttt agtgagagaa acgttgaaaa aagagtccct taagaaattt
     1201 atatcagagc agtttcaggg gtataatatt ttgaaaaaaa cctattctaa aaagactcat
     1261 accctaaagc taaccatttc aggaaattat ttgacagaag aagaactcga tatgatttca
     1321 agtaagagag gtgactatgg tttaagtgat gtttctgttc aagtttcaca attgtctgat
     1381 tcagaacaac ttagtaagga agagctggtg gagtatttct tccagtatat caaggataag
     1441 gaagcaaaag aaaaggagaa agccaataaa tttgatacag agtctgagga gcaataattt
     1501 cttgagaata gctggtttct ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt
     1561 ttaagtataa aacttttctt ctattatagt agctaagtct tgacagggtt caaaaaatgg
     1621 tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta cggcaacaaa
     1681 aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa
     1741 gacgattgaa aaatatctag gcagaaacta caaggtttta gccagtgtcg ggcatatccg
     1801 tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac cgcaatatat
     1861 caatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa
     1921 taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt ggcatttggc
     1981 ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa
     2041 ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact tggtcgatgc
     2101 ccaacaagct cgtcggatct tggatcgctt ggtagggtat tcgatttcgc ctattttgtg
     2161 gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc ttaaactcat
     2221 cattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga cagttgatgc
     2281 tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag atggtaaaaa
     2341 gatgaaactg accagcaatg acgaagtcaa ggaagtcttg tctcgtctga ctagtaaaga
     2401 cttttcagta gatcaggtgg ataagaaaga gcgcaagcgc aatgctcctt taccctatac
     2461 cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc gaaaaaccat
     2521 gatggttgcc caacagctct atgaaggaat taatattggt tctggtgttc aaggtttgat
     2581 tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg aggcggcaag
     2641 cttcattacg gatcgttttg gtagcaagta ttctaagcac ggtagcaagg tcaaaaacgc
     2701 atcaggtgct caggatgccc atgaggctat tcgtccgtca agtgtcttta atacaccaga
     2761 aagcatcgct aagtatctgg acaaggatca gctcaagcta tataccctta tctggaatcg
     2821 ttttgtggct agccagatga cagcggccgt ttttgatacc atggctgtta aattgtctca
     2881 aaatggagtt caatttgctg ccaatggtag tcaggttaag tttgatggtt atcttgccat
     2941 ttataatgat tctgacaaga ataagatgtt accggacatg gttgttggag atgtggtcaa
     3001 acaggtcaat agcaaaccag agcaacattt cacccaaccg cctgcccgtt attctgaagc
     3061 aacactgatt aaaaccttag aggaaaatgg ggttggacgt ccatcaacct acgcgccaac
     3121 cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt ttgaaccgac
     3181 agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata tcgtaaacgt
     3241 gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa aagagcagtg
     3301 gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcca aggctgaaga
     3361 agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg aagtgtgtgg
     3421 cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta gcaatttccc
     3481 agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc caagctgtca
     3541 tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctattctatg gttgcaatcg
     3601 ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact gtccaaaatg
     3661 tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa
     3721 aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta aatttcaggc
     3781 tccttttggt tagaacttga caaaatacat cattttatgc gaaactagaa gaagattatt
     3841 ttaactagga gaagttatgc gtcttatcta tctgataatt ggttttttat cactggcctt
     3901 ggctattgtt ggggttgttt tacccttgtt gccgacaacg cctttccttt tgttgtctat
     3961 tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata ccaagctcta
     4021 tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac gaaagaaaaa
     4081 aatcatcgtc tctatctacg tcttgatggg aatttctatt tattttgcac ctcttttacc
     4141 agtcaaaatc ggtctgggtg ctttgaccat ctttatcact tattatctct tcaaggtcat
     4201 tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga aagcatattc
     4261 ataacaatat gatataataa atttgaagta atattcaagg agaatcaaat gatttacgaa
     4321 ttttgtgctg aaaatatgac tttacttgaa aaagcgatgc aggctggagc tcgtcggatt
     4381 gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt gactaaggca
     4441 gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg gccacgtggt
     4501 ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat tcgtttgact
     4561 gctcaggctg gaagtcaagg ggttgtattt ggagctttaa ctgctgataa aaagttggat
     4621 aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt ctttcacatg
     4681 gcctttgatg aactaagtga tgaagatcaa ccggaagcta ttgactggct cagtcaagcc
     4741 ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga aaaacgtttt
     4801 gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct accaggtggg
     4861 gggattgacc ttgaaaaccg tcaaaccttt atcgaccagg tgggggtaac acaattgcat
     4921 ggtactaagg ttgtttttta aaaaatagaa aggaactgct agcttttggt agcagttttc
     4981 acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc atgattatgg
     5041 ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag gtgactttgt
     5101 catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc aagagactgg
     5161 tgacctctat cctcacgttc atatggaaag catgagggga agttttgtcg gaaatgtccg
     5221 tgaggcttgt ctggagattc tttaccagat tcggaaggct tgttttgatg tgcaagattt
     5281 tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg gaaaccagtt
     5341 ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag gcaatcaaaa
     5401 gtggtatgcc gtcttgatga aaatctcttg gaataagctg gaaaagggca gagaaggaca
     5461 agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac aaaaggggat
     5521 ttatccagcc ttccatatga gcaagcgcta ctggattagt gtgtcccttg atgatacttt
     5581 atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct ctaaaaaatg
     5641 aaatatttta ataattttca tgaactttca attagctaaa tattctttac tgaagaaatt
     5701 ttcagaaaat atagaattta ccacaccaga ggaatatggt gccatcttca aatacctgat
     5761 tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg atgaccttgg
     5821 aatggcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg ttgaagggac
     5881 tatcaatggt attagggagc gagctggaaa tgctgctttg gaagaaattg cagtggctct
     5941 caatattcgc caagattact accaagtaga aaccagtatt gtcctaaatg agaccatcaa
     6001 tacgtcagaa atggtttctc gcttctctgg tattccagtt cctaaaaaca aagccgtcgt
     6061 tggtggcaat accttctccc acgaatctgg tattcactaa gatggagtcc ttaaaaatcc
     6121 tctcacttat gagatcatca cacctgaatt ggttggtgtt aagattccgc ttggaaaatt
     6181 atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt ttacagaaga
     6241 ggatatcaaa tcactctttg ctaagttcaa ggcactggcc gataagaagt aagaaatcac
     6301 agatgcagat attcgagctt tggtagctgg aaccatggtt gaaaatccag aaggcttcca
     6361 ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc tcgttagcct
     6421 agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt ccgttgaagc
     6481 aatctttaac gctatcgata agttctttaa ccaatctgtt cgtttggtgt cctacactat
     6541 cgatgcagta acagatggaa tcgatgccca ggatcgggtt ttggtcactg ttgaaaacag
     6601 agatacagaa accatcttta atgcagcagg gcttgatttt gatgtgttga aggcttctgc
     6661 tattgcctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg agatgggatg
     6721 cagtgtttct taccatgata tgcctagtgt gtaaaggaga aggctatggc aaagaaaata
     6781 gtagctctag caggagacgg aattggccca gaaatcatgg aggttggttt agaagttctg
     6841 gaggctctag ctgaaaaaac aggttttgac tatgagattg acagacgacc gttcggaggt
     6901 gcagatattg atgcagcatg gcctccctta cctgatgaaa cccttaaggc aagtagggaa
     6961 gcagatgcta tcctactagc agctatcggt agtcctcagt atgatggagc agtggttcgc
     7021 cctgaacaag gcctgatggc tctccgtaag gaactcaatc tttacgctaa tattcgtcct
     7081 gtaaaaatct ttgacagtct caagcatttg tcaccactca aactggaacg aattgctggt
     7141 gtagactttg tcgtggtgcg tgaattgaca ggcgggattt actttggaga tcatattctt
     7201 gaagagcgca atgcgcgtga tatcaacgac tatagctatg aggaagtgga gcggattatt
     7261 cgcaaagcct ttgaaattgc aagaaatcgc agaaaaatcc ttactagtat cgataagcaa
     7321 aatgttctag cgacctcaaa actctggcgg aaagtagctg aggaagtcgc acaggatttc
     7381 ccagatgtaa ccttggaaca ccagctggta gactcagctg ctatgcttat gattaccaat
     7441 cctgctaagt ttgatgttat tgtaacggag aatctttttg gagatatttt atctgatgaa
     7501 tcaagcgtct tatctggtac acttggggtt atgccatcag ccagtcattc cgaaaatgga
     7561 ccaagtctct atgaacctat tcacggttca gcacctgata ttgcaggtca aggaattgcc
     7621 aatcctattt ccatgatttt atcagtttcc atgatgttga gagatagttt cggacgttat
     7681 gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc tggcggcagg aattttaacg
     7741 agagatatag gaggtcaggc ttcaacaaag gaaatgacgg aagctattat tgcaaggtta
     7801 tgaagttaga cgaaaaaatt actctagtcc ttttgatttg gaatgtcatc attttcttga
     7861 tttatggcat tgacaaattc aaggcaagaa gaagagcttg gcgcatccaa gagaaaatct
     7921 tactcatttt agcccttact tgtggtggtt ttggggcctg gttagctgga atcacttttc
     7981 accacaagac tcgaaaatgg tactttaaaa cagtttggtt tcttgggatg gtgaccacac
     8041 tagtagcctt atattttatt tggaggtaat ggatggcagg gtcttcgagg gaacacgctg
     8101 cttgggctct agcggactat ggttttaagg tcgtgattgc aggatctttc ggtgacattc
     8161 attacaataa tgaactcaat aatggcctgt tgccaatcgt tcagcctaga gaggttagag
     8221 agaaactagc ccagctaaaa ccaaccgacc aggtaactgt ggacttggaa caacaaaaaa
     8281 tcatctcacc agttgaagaa ttcaccttcg agatagatag cgagtggaaa cataaactcc
     8341 taaatagttt ggatgatatc ggtattacct tgcagtatga agagttgatt gctgcttatg
     8401 aaaaacaacg accagcctac tggcaggatt agaaaaaata gaaaaggaaa tatagtaaac
     8461 tgaaataaga tgtaaacaaa tgaattagag cttaacatcc atttccagca attttttaga
     8521 aactacagtg gactattctg gattcaacac attataaaat tatgacaaaa cacattcaca
     8581 agaaggctac gacattttaa aaggtgaggg cggatgtatc gtttgcccta ctaaagttgg
     8641 ttacattatc atgaccagca acaaggcagg acttgagcgt aagttcgcag ccaaagaacg
     8701 taagcgtaac aaaccaggtg ttgttctctg cggtagcatg gatgaacttc gcgctttagc
     8761 gcaactcaac ccagaaattg aagcattcta ctaaaaacat tggatgaaga tattcttctt
     8821 ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata cggggatggc
     8881 cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa
     8941 gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta cgcctcatat
     9001 gcttcaatga caaaacgatt gaaactcgct atgagagcaa ggtgtaatgg tgtctatggt
     9061 cgataaggac ggcaaactca tcccagaaca aggaggagca cgttcaactt caccagcacc
     9121 agttgtgatc cgtaaagggc ttgacattga taaaatcatg atgcacctgt cagatacttt
     9181 taactcatgg gactaccgtc aggttgagta ttattaagat aaaaaaagaa gtctagtgtt
     9241 atgagatatt aaagctccta acactggact ttttgtttag aatttctttt ctttttct
//
LOCUS       DAVLTG010000066         9085 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLTG010000066 DAVLTG010000000
VERSION     DAVLTG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.067"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            1..168
                     /locus_tag="VYN12_001831"
     CDS             1..168
                     /locus_tag="VYN12_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV1416151.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(228..365)
                     /locus_tag="VYN12_001832"
                     /pseudo
     CDS             complement(228..365)
                     /locus_tag="VYN12_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            649..732
                     /locus_tag="VYN12_001833"
                     /pseudo
     CDS             649..732
                     /locus_tag="VYN12_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            781..864
                     /locus_tag="VYN12_001834"
     CDS             781..864
                     /locus_tag="VYN12_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1416152.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            989..1726
                     /gene="erm(B)"
                     /locus_tag="VYN12_001835"
     CDS             989..1726
                     /gene="erm(B)"
                     /locus_tag="VYN12_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1416153.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            2081..2635
                     /locus_tag="VYN12_001836"
     CDS             2081..2635
                     /locus_tag="VYN12_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1416154.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            2639..5557
                     /locus_tag="VYN12_001837"
     CDS             2639..5557
                     /locus_tag="VYN12_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HEV1416155.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(5631..5852)
                     /locus_tag="VYN12_001838"
                     /pseudo
     CDS             complement(5631..5852)
                     /locus_tag="VYN12_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6357..6779
                     /locus_tag="VYN12_001839"
     CDS             6357..6779
                     /locus_tag="VYN12_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1416156.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            6776..7006
                     /locus_tag="VYN12_001840"
     CDS             6776..7006
                     /locus_tag="VYN12_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1416157.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            7467..7670
                     /locus_tag="VYN12_001841"
     CDS             7467..7670
                     /locus_tag="VYN12_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV1416158.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            7752..8969
                     /locus_tag="VYN12_001842"
     CDS             7752..8969
                     /locus_tag="VYN12_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1416159.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3172 a         1498 c         1702 g         2713 t
ORIGIN      
        1 ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa gggaagatac tgaattaaaa
       61 aaattccccc tctattgtcc gaaatgcaga caagaaaatt taattgaaat aaagcagttc
      121 aaagtaactg tgattacaga gccagacgca aagacgcaga gccgataaaa tgagattaat
      181 acaatctcat tttatcggct ctttccgtta tgtatggatt cttttaatta gtcttcgatg
      241 tttcttgctt cgttgatacc gctggctaaa gattccatta aggatagttc tttgtctgta
      301 aagctatcca tgtatttctc tatctgtaat cgtcgggtgc tttttaccaa gttattagca
      361 ggtaggggtc ccgagcgcct acgaggaatt tgtatcgata agaaatagat ttaaaaattt
      421 cgctgttatt ttgtacattt aacttgacgg tgacatctct ctattgtgag ttattagtgg
      481 tacagttttc aaccgtttta attataaaaa agtggtgcat ttttaaattg gcacaaacag
      541 gtaacggtta ttgcaggtgt atttcttatc tatgggttta acatggattt tatcattaaa
      601 atcatgagta ttgtccgaga gtgattggtc ttgcgtatgg ttaaccctaa agttatggaa
      661 ataagactta gaagcaaact taagagtgtg ttgatagtgc attatcttaa aattttgtat
      721 aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc
      781 atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa
      841 aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta
      901 tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg tatttgttta
      961 tagatgtaat cacttcagga gagattacat gaacaaaaat ataaaatatt ctcaaaactt
     1021 tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga
     1081 taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag
     1141 taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt
     1201 aaaactgaat actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa
     1261 caaacagagg tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa
     1321 aaaagtggtt tttgaaagcc gtgcgtctga catctatctg attgttgaag aaggattcta
     1381 caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat
     1441 tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt
     1501 cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac
     1561 gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt
     1621 tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accattactt atgagcaagt
     1681 attgtctatt tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct
     1741 tttgtaaatt tggaaagtta cacgttacta aagggaatgt agataaatta ttaggtatac
     1801 tactgacagc ttccaaggag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat
     1861 aaggaataga tttaaaaatt tcgctgttat tttgtacaat aaggataaat ttgaatggta
     1921 ccataaacga ccgtttatgg taccttttca ttttcctgct ttttctaaat gttttttaag
     1981 taaatcaagt accaaaatcc gttccttttt catagttcct atatagttat acttaatgag
     2041 ttatggtaca tttaaattat aaaattaagg aggttttttt atgatttttg gctatgctcg
     2101 agtgagtacg gatgatcaaa atcttagttt acaaattgat gcacttactc attatggaat
     2161 tgataaatta tttcaagaaa aagtaactgg tgcgaaaaaa gaccgaccgc aattagaaga
     2221 aatgatcaac ctactacgtg aaggagattc tgttgtcatt tacaagttag atcgaatttc
     2281 acgatcaact aaacatttga ttgaactttc tgaattattt gaagaactta gtgtcaattt
     2341 tatatctatt caagataacg tagatacttc aacgtctatg ggaagattct ttttccgagt
     2401 tatggctagt ttagcagaac tggaacggga tattattatt gaacgaacta actctggtct
     2461 taaggcagcc agagtccgag gaaaaaaagg gggccgtcca agtaaaggta agctatcaat
     2521 tgatttagct ttaaaaatgt atgacagcaa agagtattct attcgtcaaa ttcttgatgc
     2581 ctctaaatta agcaaaacaa ccttttaccg ttacctcaat aaaaggaatg cttaagatat
     2641 ggctatgaaa agaattttaa ctacttcaca gcgtgaacaa cttctttctg tagaccactt
     2701 atcagaagag gattttaaag cgtattttag tttttctgat tatgatctgg aggttattaa
     2761 tcaacaccgt ggaaaggtca ataaactagg atttgcgata caactttgtt tggcccggta
     2821 tcctgggtgt tctttaagta attggccgat taaatcaacc agactaactt cttatgtgag
     2881 tcgacagctc catcttgatg caattgattt aaattcatat gatcatagaa atacacgtgc
     2941 aaatcacttc aacgagatct tagaagtatt caactatcat cgattcggta gtgctaatac
     3001 acaaaaacag ttaatagaat atttaattga actagcttta gaaaatgatg actctatcta
     3061 tctaatgaaa aaaacaattg atttcttaac tcgaaaaaga attatttttc catctatagc
     3121 tacacttgaa gacattataa gccgctgtcg agataaagca gaaaacaact tattttcaat
     3181 attactctgt tcattaacag atatacaaat tgaaaaacta gagagtttgt ttcaaattta
     3241 tgaagagacg aaaataacta aactcgcttg gctaaaagac attccaggta aggcaaatcc
     3301 agaaagcttt atgagtattt gtaaaaaagt ggaagtgatt gcttccatgg gactcgggac
     3361 aattaatgtc tcccatatta atcggaacag gtttcttcag ctagctagac taggggaaaa
     3421 ttatgatgca tatgacttct cccgttttga gcttgaaaaa agatactctt tacttattgc
     3481 ttttttagtc aatcatcatc aatatctgat cgatcaactg attgagatta atgaccgcat
     3541 tttagcaagt attaaacgca aagggacacg tgattcacaa gaacagttaa aagaaaaagg
     3601 aaaattggct actaaaaaat tggaacatta tgcttcttta attgatgctc ttcactttgc
     3661 aaaagataat gatagtaatc cttttgacga aattgaacga atcatgcctt gggaagattt
     3721 agtacaagat ggagaagaag ctaaaaaaat tacaggtaat aaaaatcatg gctatttaga
     3781 aatggttcga aataaagcta attacctccg aagatacacg ccaatgttat tgaggaccct
     3841 ttcgttcaaa gcaactccgg cagcaaatcc agtcctcatg gccctaactc aactaactga
     3901 tttacacaat agtggtaaaa gaaaaatacc ggcagatact tctactgatt ttgtgagtaa
     3961 aaaatggaaa agccttgttc ggccagaaga ggggaaaata gatcggtctt actatgagtt
     4021 agtagctttc accgagctaa agaacaatat tcgatcagga gatatttcag ttgaaggaag
     4081 tatgatccat cgaaatattg atgattactt agttgattta tctgcttgta ttgattcaga
     4141 aactattcca gacacgtttg aggactattt aaaggatcgg gaaataattt tagatttaca
     4201 gcttcaattt tattcgacag ttgataagag aatttcaaga gcaaacctta aaaagttgga
     4261 aaaagttaca cctagcgaag cagaaatata tagaaaaaaa ctttattcaa taattcctaa
     4321 gataaggctt agtgatcttt taattgaggt ggacagttgg accaactttt cacaagaatt
     4381 tagtcatgat tctacaggga aaccgccgag tgaacaagaa agaaaaatta tttttgctgc
     4441 tttgctgggt ttagggatga atattggtct tgaaaaaatg gcccaatcaa ctcctggaat
     4501 ttcttattct cagttagcca atgccaaaca atggcgcttt tataaagaag ctctgactcg
     4561 tgctcaatct gttttggtta attatcagtt aaagcttcct gttgcagact tttggggtga
     4621 aggaaaaacc actgcttcag acggaatgcg cgtcccagtg ggcgtctcag ctctaaaatc
     4681 cgatgttaat ccacattaca aaagtatgga aaaaggagct acaatgattc gatcaataaa
     4741 tgataggcat acgactcatc atatcgaggt tgcttcaact aatacaaggg aagctactca
     4801 tacccttgat ggcctacttt atcatgaaac agatctagat attgaggaac attttactga
     4861 tacaaatggg tattctgatc aggtgtttgg aatgaccgca ttactaggct ttgattttga
     4921 acctcgcatc agaaatataa aaaaatcaca attattttct atcaaatcac cttcctacta
     4981 ccctaactta tcagaagata taagcggaaa aatcaatgta aaaattattg aagaaaacta
     5041 tgatgaaatt aaacgaatcg cctattcgat tcaaacagga aaagtatcta gttctttact
     5101 attaggaaag ctaggctcat acgcacgtaa gaatagagta gctcttgcac tgagagaact
     5161 aggtcgcatt gaaaagagca tttttatgat agattatatt acagatagtg agctacggcg
     5221 aaggatcact catggactaa ataagacaga agcgattaat gctttagcta gagaactatt
     5281 ttttgggcga cgcggaaaat ttatggagcg cgatattcgc cgacaacttc aaagtgctag
     5341 tgcgcttaat gtgttaataa atgcaataag tatatggaac gccgtctact tacaagcagc
     5401 ttataattat ctcgtcaaaa tagatcccga agtaactaag tatatgaagc atgtatctcc
     5461 tattaattgg gagcatatca cttttcttgg agagtataaa tttgacttgt tatctattcc
     5521 taaacactta agagaattga atataaaaaa taaataggcc ttgaaacatt ggtttagtgg
     5581 gaatttgtac cccttatcga tacaaattcc cactaagcgc tcgggacccc aggtaagaaa
     5641 aattcatcaa cggaaacatg aagtaacgat acaaggtcat aaagaacttg tatgctgggg
     5701 tgttgccctt tattttcaat attagttaag taccgtgggt caatttcaat caatgctccc
     5761 acttgttcac gagttaaacc tcgtttcaat cgagcttctt taatggctaa accaaaggct
     5821 ctaaaatcat atttatcttc ttttttacgc atagtagacc acctctatac attttattgt
     5881 tcctactgaa ttaaaaacag gtatagaaaa acgtgttata tggtttatag gtttatattt
     5941 aataaaaagc actactaaac gccaataaaa aaaaccgtta tatggtagtg ctatttacgc
     6001 tgttaaaata ttgtatatta cttccaaatg gcggtttgtt ggaggtcaac gtcgccatga
     6061 agtacatcat atacaataaa tttccttaca ttgggttctt gtcaaaaaaa gtcgtctatc
     6121 tgcaatagat aagtacgtcc accaatgtgg ttttataaat catatagata gaataacaga
     6181 agcatgtaaa cagagaaata aatctgttta tatgcttttt tggctattca gaactttttt
     6241 acaaagttta tttatcagta atgcaacaaa tccccctttc acattgggac taagagtgaa
     6301 aggagataaa cgagcaaggc tcacttcctt tcctagacag aaagggggtg agaaacatga
     6361 aaccatcttc ttttcagacc acaatagaaa atcagtttga ctatatctgt aaacgtgcta
     6421 tggaagacga gcgaaagaat tatatgcttt atctttcaag gattgcaaag cgtgaggtgt
     6481 ccttttcgga tgttggcgat tatcttgtta gccagtttgc gacaacagat aactattcaa
     6541 ctgactttca gatttttaca ctcaatgggt tatcagtagg cgttgaaaat gatttgttga
     6601 gtgaagcatt acgtgagttg ccagacaaga aacgtgaaat tctactgctg ttttacttta
     6661 tggacatgag cgattcagaa attgcagacc tgttgaaatt gaaccgttct actgtctatc
     6721 ggcatagaac cagtggacta gccttaatta aaaagtttat ggaggaattt gaagaatgaa
     6781 aacacaatat cctatgattc cctttcctct cattgtaaag gcaacagatg gcgataccga
     6841 agcgattaac cagattctac atcattacag agggtacata acgaagcgtt ccctacgact
     6901 tatgaaagat gaatatggca atcaaagtat ggtcgttgat gaagtcttac gtggaagaat
     6961 ggaaaccaga ctgattacaa agattttgtc atttgaaatt aagtaatatc ctctctcctt
     7021 tcgtggaagc gtgctaaacc attccacgct tcccgaacag ggaggtttgt tattccacca
     7081 aagcatattg agctttcaat gtgttttgat aggctaacga gccattgttc tttgaaaact
     7141 gaataaaagt aatcgaatac gtttcgataa gaaaagagcc aacggaacta accgccatga
     7201 cctatcttat aaagatagcg agcgattcat gttagtgatc cgagaagcaa tctttagcag
     7261 gattgcctgc aacgacattc ttatcgtgat aatgatactc ccatacagtc aatagtccga
     7321 gcgtgataaa accgtcgcag gcaatgagta tggctacatg agaaccatgc aggggtggaa
     7381 ctcccgtgag ctttgctaaa gctgttcgat tgctggtaaa acaactttta tgaaatccaa
     7441 ataagtgatt tggaaaggag gattttatga agcagactga cattcctatt tgggaacgtt
     7501 ataccctaac cattgaagaa gcgtcaaaat attttcgtat tggcgaaaac aagctacgac
     7561 gcttggcaga ggaaaataaa aatgcaaatt ggctgattat gaatggcaat cgtattcaga
     7621 ttaaacgaaa acaatttgaa aaaattatag atacattgga cgcaatctag cgtcgccaaa
     7681 gggtcttgta tatgataaaa tagtattaag tcgtatcaag gctctttcca taaaggaaag
     7741 gagcaaatgc catgtcagaa aaaagacgtg acaataaagg tcgaatctta aagactggag
     7801 agagccaacg aaaagacgga agatacttat acaaatatat agattcattt ggagaaccgc
     7861 aatttgttta ctcgtggaaa cttgtggcta cagaccgagt accagcagga aagcgtgatt
     7921 gtatctcact tagagagaaa atcgcagagt tacagaaaga cattcatgat ggtattgatg
     7981 ttgtaggaaa gaaaatgaca ctctgccagc tttacgcaaa acagaacgct caaagaccaa
     8041 aggttagaaa aaacactgaa actggacgca aatatcttat ggatattttg aagaaagaca
     8101 agttaggtgt aagaagtatt gacagtatta agccatcaga cgctaaagaa tgggctatta
     8161 gaatgagtga aaatggttat gcttatcaaa ccatcaataa ctacaaacgt tctttaaagg
     8221 cttcattcta tattgctata caagatgatt gtgttcggaa gaatccattt gactttcaac
     8281 tgaaagcagt tcttgatgat gatactgtcc ctaagaccgt actaacagaa gaacaggaag
     8341 aaaaactgtt agcctttgca aaagctgata aaacctacag caaaaattat gatgaaattc
     8401 tgatactctt aaaaacaggt cttcgtattt cagagtttgg tggtttgaca cttccagatt
     8461 tagattttga gaatcgtctt gtcaatatag accatcagct attgagagat actgaaattg
     8521 ggtactacat tgaaacacca aagaccaaaa gtggcgaacg tcaagttcct atggttgaag
     8581 aagcctatca agcatttaag cgagtgttag cgaatcgaaa gaatgataag cgtgttgaga
     8641 ttgatggata tagtgatttc ctctttctta atagaaagaa ctatccaaaa gtggcaagtg
     8701 attacaacgg catgatgaaa ggtcttgtta agaaatacaa taagtataac gaggataaat
     8761 tgccacacat cactccacat agtttgcgac atacattctg taccaactat gcaaatgcag
     8821 gaatgaatcc aaaggcatta cagtacatta tgggacatgc taatatagcc atgacgctga
     8881 actattacgc acatgcaaca ttcgattctg caatggcaga aatgaaacgc ttgaataaag
     8941 agaagcaaca ggagcgtctt gttgcttagt agtacaaatg aatttactac ttatttacca
     9001 cttctgacag ctaagacatg aggaaatatg caaagaaacg tgaagtatct tcctacagta
     9061 aaaatactcg aaagcacata gaata
//
LOCUS       DAVLTG010000067         9028 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLTG010000067 DAVLTG010000000
VERSION     DAVLTG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.068"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(351..1199)
                     /gene="dprA"
                     /locus_tag="VYN12_001843"
     CDS             complement(351..1199)
                     /gene="dprA"
                     /locus_tag="VYN12_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1416160.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1295..1984)
                     /locus_tag="VYN12_001844"
     CDS             complement(1295..1984)
                     /locus_tag="VYN12_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1416161.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1996..2874)
                     /locus_tag="VYN12_001845"
     CDS             complement(1996..2874)
                     /locus_tag="VYN12_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1416162.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2864..3733)
                     /gene="licA"
                     /locus_tag="VYN12_001846"
     CDS             complement(2864..3733)
                     /gene="licA"
                     /locus_tag="VYN12_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1416163.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(3750..4772)
                     /locus_tag="VYN12_001847"
     CDS             complement(3750..4772)
                     /locus_tag="VYN12_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1416164.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4777..5484)
                     /locus_tag="VYN12_001848"
     CDS             complement(4777..5484)
                     /locus_tag="VYN12_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1416165.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5820..7307
                     /gene="tacF"
                     /locus_tag="VYN12_001849"
     CDS             5820..7307
                     /gene="tacF"
                     /locus_tag="VYN12_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1416166.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7317..8120
                     /locus_tag="VYN12_001850"
     CDS             7317..8120
                     /locus_tag="VYN12_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1416167.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8122..8931
                     /locus_tag="VYN12_001851"
     CDS             8122..8931
                     /locus_tag="VYN12_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1416168.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2839 a         1822 c         1519 g         2848 t
ORIGIN      
        1 tgttcacatc ttatttcaat tcactatact ttcccttata ctcaatgaaa atcaaagcgc
       61 aaactaggaa gctagccaca ggttgctcaa agcactgctt tgaggttgta gataagactg
      121 acgaagtcag ctcaaaatac tgttttgagg ttgcagatgg aagctgacgt agtttgaaga
      181 gattttcgaa gagtattata tgagaaaaat cctctactct actaatccac ttagaaaaaa
      241 cgcatattat caagtgttaa aaacttgcta atatgcgttt tattatggaa atgttgggtt
      301 cattttctct taaaattgat tttttcttag aattttagct taggtcattt ttaaaattca
      361 aattccgcaa gaacatcttg cccactggtg accaattttg ctccttcttg aatcaaatga
      421 tggcaaccgt ctgatagtcc atctaaaatg ctaccaggaa tagcaaagac atcgcgtcct
      481 tcttccattg ctcgctcaca cgtaatgaga ctacctgaac gcatcttagc ctctgctaca
      541 atcacaccac gacaaagtcc agcaatgatg cgattacggg caggaaaatg aaatttcaga
      601 ggttgttcgc caggtccata ttcacttaga accagatgat cattgccgat gtagtcttgc
      661 aagcgtttat tggctttagg ataaaacaca tccagtcctg ttccaatcac tgcaatggtt
      721 tttccgccat tctgaagagc tgccatatga gctgctgtgt caatgccctt ggccagacca
      781 ctgacaataa ccagttcatt ttccaagcct tgaatgactt tttcaactga cttagctccc
      841 tgtttgctac aagcacgact gcccacgacc gctaccttcg ggaatttcag gaggtcaaga
      901 tttcccttgt aaaataaaag tacaggcgca tcatatattt cactcaaatc ccaaggataa
      961 cagtcatcta aaatagagaa agatggaaat ttttgaaact ctttcgacaa atgcgcatcg
     1021 tctatctgaa aataacgttc cataaaaacg gctggattac ggcaacctga tatatctgca
     1081 atatcaccca acaaaagctc ctgatcaaca ttttcaccgt attctagcac tttcaaaatc
     1141 tgttgattgg tcaaacctga tttttttaac ttatagattt catagtttgt gattttcata
     1201 aataactcca tttctttttc tactcatcta tctattcgta aaagttcgta aaaaatcaaa
     1261 aaacatccga ctattttgtc agatgttgga atctttaatt ttcgttttta agaatttctt
     1321 ctaatttacg atagtcttgg acactatcga tctcataaat gctattgcct tctaattctt
     1381 caacatagac atctagctct ttgatattat ccttaaccat attgtcccaa tagagatcaa
     1441 caaattcacc acttgcataa gccttgtcga taaagctgac aatcttttct gcagttggag
     1501 catcccagaa ggatacacca ctaaggatgc gacctgcctt gctatcaaca ataatgtctt
     1561 gaaccttgta gtcatctcca tagaccaaga accattcgtt ggtacaatct tcacgataaa
     1621 cactaaaata agtcgaacgt gtcaaatcat tgcggaacat atttttaaag agataattgt
     1681 cagcatcaat aacatagctg ttggccaatt cttcttttac aagatagaga gagtaaaagt
     1741 tattgtagtc agcgtattta tcattgaaaa cgaggcgaac accgtatttt tcttttaagt
     1801 aatcgaattg ttctttaaga taaccaacaa tgatgatgat gtcattgatt cctttttctt
     1861 tgagaaactc aatttggtat tcaatcaaag gtttttgatt aacctgaacc aaggctttag
     1921 gggtattttc agtcatagga cgcaagcgag ttcccaatcc cgctgctaag ataatggctt
     1981 tcacacgaat ctcctttatt ctttaataat aatataaact ccagcaatga cgacaagtga
     2041 cgtcataatg gtcagcatat ctagcggtgc acccaaaaaa acaactgcaa acaagaccgt
     2101 ccatactaca tagctcacgt tcaagcctgt agccttggct ggttgcaagc gattgatagc
     2161 gatataataa gccaagtagg aaatcatatc aaaggctgca aaaacaatca tgagacctag
     2221 caattgtcca ttggctactg cagtaaatga ctgatgagag aagagcacaa tcacaagata
     2281 ggacaagaac gaagtcactt gacggattaa gagggcttcg atttcactca gttcactttc
     2341 catagcaaag gagctaagaa cactctcact tccccatgca atagcacaaa ccaaagcaca
     2401 gagaatccca atgtagaagg aattaacctg ttcaacctta taggtctggg caataatccc
     2461 tccaataatc aagacaatcc caaatacagt atttttcgaa atcttgtgct tcaaaaagaa
     2521 aaaagccaat agaactgaaa tcgcagggta aatagccgat acagatgaag ctaaagaact
     2581 tccgatatac ttaactgcat aaagattggc ctgcataccg atagggcctg ctagcaaggc
     2641 tccgatgata acactgacat tgcgaatatt taagaaaatt gagaggcgaa ctttcccttc
     2701 ttttaccaag agaaaagcta gtaagataaa gatgctcaaa aaatcatgag ctgcagccac
     2761 cacaaagggt gacaaatctg taaaaatcga aaagatataa gcactaaccg ttagacccaa
     2821 gccccagaaa atacctgaga gaaggccaaa aggaactccg tttttacttt tcatctgaac
     2881 ctccataaga agccaaacct ttaatagctc tttggtaacg attcacacca tagtcaccaa
     2941 aatcttcacc ttgctcttcc ttatagacag tccatagact ccaaatagta tcttgtaaaa
     3001 ttttataaat agcaatcttt tcatgagaaa ccggtgtttg gtcactctca tagtgagata
     3061 agaaagtttc ttcctcttgg gaagtgaatt cagactctaa aaagagggca gccaaatccc
     3121 acattggatc attcattgat gaatattccc agtcaatcaa ataaagtcgt ccttgaggtg
     3181 attcgataaa gttttcaggc accaaatcga tatgacaaga ttttctgtca acacctaagt
     3241 cagccagtct tttctctaag gagaagactg catttctaac agattcatag ttggcataag
     3301 gaatttgttc ttcaatcaag gattcgtatt ttttgatttc ttcaaaagga gcaaattctc
     3361 ctcttaattc cttagcagac gtatgaatag tttgtaatat tggagtaatt ttgtcgaact
     3421 tggtcttgat tgacgttgaa tcaagcgtaa tcgcagattc gatatactca tttactttga
     3481 taccagcttc aatatcaaaa agataatttt ttacatctaa gcctaaatcc tttagtagtt
     3541 caagattgta cttttcatct tgtcgattga taagcttttc tgtcccttta ccaaagaatt
     3601 taacaatgta ttgcttattt gttgttttgg ccaaatagtt ttgattggtc attccaccca
     3661 gttgttcaac actgaggact tcctcttctt gactaagtaa ggaagaaatt ttttctttaa
     3721 tgattttctc cacaattaac ctccagtact tatacttccc acttaaacac tgttttaaag
     3781 gctgtgttta aatcggttgc aaagacacga tgaatatctt taatttctct tacaggttct
     3841 tctagataaa ggatattttt aagacgatta gcaaatttct tgacttccat catttggata
     3901 gcattttcaa aatcaatgcg accagaacga gatgacccaa ccaaaatcaa gcccttttct
     3961 aaggcatcgc gagtattgag attgacttta tattcgctaa ctcccatcat gagaatcgtt
     4021 ccctgaggac gaatgtagcg aatcaagtca ttaatagctg gtccagtacc atcaccacca
     4081 caacattcaa aagcatggtc aaaggccaaa tcttcaggaa tattatccgt aatatagcat
     4141 tctttggcaa atgagaagag ttccaacttt tcccaatgac gaccaataac cacaatctct
     4201 gcttctggca aagtatagtt gataatattg gcaaccacaa aagctaaact tccatctcca
     4261 ataacggcga tccgctcccg cttgctatga gcaagagtca atagacgatt catagcgtgc
     4321 atgcccacac tgacaaactc tgtaatggct gcaaccgtat cttcaatagc atcataagcc
     4381 accacacgat ctttagggag agaaacaaac tctctcataa agccatcaaa tccactagac
     4441 aagaaatggg tccctgtcat gtagttttca tagaattctt catcactctg cataggagac
     4501 tgattgggaa tcatgacaac tttttgacca acctcgtagg ttccggtcgg gtcagaaatg
     4561 acggttccac atgactcgtg aatcattgcc attggaagct ttttattcaa aatcttggga
     4621 tcacgttttc cctgatagta acgctgatcc gcatgacaga cagccatgta gttgggacgg
     4681 ataaggatat gattctcttg gtcaatagcc tcttcctgat atttgacatt gataaactta
     4741 ggcttagtta gttgataaat ttgattaatc attttactag tctttctcaa tcatactttt
     4801 tgcaatcttc aaatctgtta cggttgtaat cttcagattt gagtattcac ctttggccaa
     4861 agccacatct tttcctttga tcacaaagat tttacatgca tctgtcaaga tttccttctc
     4921 ttcatcagaa agagatccat aaaggtccat gaagtccttg caacggaatg tttgaggtgt
     4981 ttgtccttga taaaggtgag cacgatttgg aatatctgta ataaattgac cattggtact
     5041 ttcaacgata gtatcaaccg cttctaccac tgtgtccact gcgtcatgat tttgggcaag
     5101 ttggatattg tcctgaatca tgcgaagtgt aataaatgga cgaacagaat cgtgggtaac
     5161 aacgatatcc tctggagtaa gcggacgata agcatcaatg gcttcaatga tgttcttaat
     5221 acttgtattg cggtcagcac caccctttgt aatgatgata cgttccttat aaagaggaag
     5281 atatttatct acaagatctt ctgcatgaga aacccagtct ccatgaacac caactacaat
     5341 tttttcaata cttggctcca agacaaattt ttcaattgta tgaatcaaaa taggtcgatc
     5401 acctagctct aaaaattgtt ttggcaagtt actgatcccc atgcgtgtgc cagttccacc
     5461 ggcaagaatt cctgcataaa tcatctattt tctcctttgt cttactaaaa aaacttattc
     5521 tctctattat accacaatct agtcctatca taaaagaaat actggtcctc cccttctaga
     5581 ataggagaat tatgcagttc tattattcaa agaaactagt ccatttctag taatgactag
     5641 gaattctgta gcaattacta ataaatggct gcgaaatttt agagtccttc agaataatat
     5701 actttcctta aagaaaactt aaaacttaag atttgaaact tcaaagtgat tacttgactt
     5761 actgcccttc atttcttatt agctaacttt atgatataat gaaaaacgag gtaaattgaa
     5821 tgaaaagtat aaaattaaat gctctatctt acatgggaat tcgtgtcttg aatattattt
     5881 ttcccatcct aactggaacc tatgtcgcgc gtgtcttgga ccgaactgac tatggttact
     5941 tcaactcagt cgacactatt ttgtcatttt tcttgccctt tgcaacttat ggtgtctata
     6001 actacggttt aagggctatc agtaatgtca aggataacaa aaaagatctt aacagaacct
     6061 tttctagtct tttttatttg tgcatcgctt gtacgatttt gaccactgct gtctatatcc
     6121 tagcctatcc tctcttcttt actgataatc caatcatcaa aaaggtctac cttgttatgg
     6181 ggattcaact cattgcccag attttttcaa tcgaatgggt caatgaagct ctggaaaatt
     6241 acagttttct cttttacaaa actgccttca tccgtatcct gatgctggtc tctattttct
     6301 tatttgttaa aaatgaacac gatattgttg tctatacact tgtgatgagt ttatcgacgc
     6361 tgattaacta cctgattagt tatttttgga ttaaaagaga catcaaactt gttaagattc
     6421 acctaagtga ttttaaacca ctctttctcc ctctgacagc catgttagtc tttgccaatg
     6481 ccaatatgct cttcactttt ttagatcgcc tcttcctcgt taaaacaggg attgatgtca
     6541 acgttagtta ctataccata gctcagcgaa ttgtgaccgt tatagctggg gttgtaacag
     6601 gtgcaattgg agtgagtgtg cctcgtctca gttactatct ggggaaagga gacaaagaag
     6661 cctatgtttc tctggttaat agaggtagtc gaatctttaa cttctttatc attccactga
     6721 gttttggact catggtttta ggaccaaatg ccatcctact ttacggtagt gaaaaatata
     6781 tcggaggcgg catcttgacc tctctcttcg cttttcgtac gattatcctg gccttagata
     6841 ccattcttgg ttcccaaatt ctctttacca atggctatga aaaacgtatc acagtttata
     6901 cagtctttgc tgggctactc aatttgggct tgaatagtct cctctttttc aaccgtatcg
     6961 tggctcccga atactactta ctgacaacta tgttatcaga ggcttctcta cttgttttct
     7021 atatcatttt catccataga aaacaactca tccacttggg acatatcttt agctatactg
     7081 ttcgatactc tctcttttca ctttcctttg tagcaattta tttcctgatt aatttcgtgt
     7141 atcctgtgga tatggtcatt aatttgccat ttttgattaa tactggtttg attatcttgc
     7201 tatcagctat ctcttatatt agtctacttg tcttcacaaa agatagcatt ttctatgaat
     7261 ttttaaacca tgttctagcc ttaaaaaata aatttaaaaa atcataggag tttaaaatga
     7321 aacaactaac cgttgaagat gccaaacaaa ttgaattaga aattttggat tatattgata
     7381 ctctctgtaa aaagcacaat atcaactata ttattaacta cggtactctg attggggcgg
     7441 ttcgacatga gggctttatc ccttgggacg acgatattga tttatccatg cctagagaag
     7501 actaccaacg atttattaac atttttcaaa aggaaaaaag caagtatgaa ctcctatcct
     7561 tagaaactga taagaactac tttaacaact ttatcaagat aaccgacagt acgactaaaa
     7621 ttattgatac tcgaaataca aaaacctatg agtctggtat ctttatcgat attttcccta
     7681 tggatcgctt tgatgatcct aaggtcattg atacttgtta taaactggaa agcttcaaac
     7741 tgctgtcttt cagtaaacat aaaaatattg tctataagga tagcctttta aaagattgga
     7801 tacgaacagc cttttggttg ctccttcgac cagtttctcc tcgttatttt gcaaataaaa
     7861 tcgagaaaga aattcaaaaa tatagtcgtg aaaatgggca gtatatggct tttatccctt
     7921 caaaatttaa ggaaaaggaa gtcttcccaa gtggtacctt tgataaaaca atcgatttac
     7981 cctttgagaa tttaagcctt cctgcacctg aaaaatttga tactattttg acacaatttt
     8041 atggagatta tatgacccta ccaccagaag aaaaacgctt ctacagtcat gaatttcacg
     8101 cttataaatt ggaggattag gatgcaatat ttagaaaaaa aagaaattaa agaaattcaa
     8161 ctagccctgc tggactatat tgatgagact tgtaagaaac atgatattcc ttattttctc
     8221 agttatggaa ccatgcttgg agccatccgc cacaaaggta tgattccttg ggatgatgat
     8281 attgatattt ccctttatcg tgaggattat gagcgtttac tgaagattat tgaagaagaa
     8341 aatcaccctc gctacaaggt tctttcctac gatacatctt cttggtactt ccataatttc
     8401 gcatcgattt tggacacttc tactgttata gaagaccatg ttaagtacaa gcgtcatgat
     8461 accagccttt tcatcgatgt cttcccaatt gatcgattta cagacttgag cattgtcgac
     8521 aagagctata agtatgtggc tcttcgtcaa ctagcttata tcaaaaaatc acgagcagtt
     8581 cacggtgata gcaaactaaa agattttctt agattatgta gctggtacgc tctccgattt
     8641 gtcaatcctc gctactttta caagaaaatt gatcaactag tcaaaaatgc tgtaaccaac
     8701 attcctcaat atgaaggagg agttgggatc ggtaaggaag ggatgaaaga aatcttccca
     8761 gttgatacct ttaaagaact gattttaact gagtttgagg gccgtatgtt gcctgttccc
     8821 aaaaaatatg accaattttt aacccagatg tatggcgatt atatgacacc accatcaaaa
     8881 gaaatgcaag agtggtatag tcatagcatt aaagcttatc gcaaaaactg attgaggggg
     8941 attatacaaa ctactaagat agaggttatt caaaaacata attttagtag aaaatgaaat
     9001 acatattccc acaataaaac gcatcata
//
LOCUS       DAVLTG010000068         8805 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLTG010000068 DAVLTG010000000
VERSION     DAVLTG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.069"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            29..184
                     /locus_tag="VYN12_001852"
                     /pseudo
     CDS             29..184
                     /locus_tag="VYN12_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            384..3659
                     /gene="rexB"
                     /locus_tag="VYN12_001853"
     CDS             384..3659
                     /gene="rexB"
                     /locus_tag="VYN12_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1416169.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3656..7306
                     /gene="addA"
                     /locus_tag="VYN12_001854"
     CDS             3656..7306
                     /gene="addA"
                     /locus_tag="VYN12_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1416170.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7521..8699
                     /locus_tag="VYN12_001855"
     CDS             7521..8699
                     /locus_tag="VYN12_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416171.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLLLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2718 a         1849 c         1875 g         2363 t
ORIGIN      
        1 tttactatag ttcaatcatt ctatcaagaa tattgaatat ataaaggcac gtaatattaa
       61 aacttcttct gatatcgaat tagagtccga tgttgatggc gataaatcag acaatctacc
      121 agtcgacatt aagatactgg gacaacacat tgaagtgtat tccgtaccta agaaacaatc
      181 ataaaactca aagccttgtt accgaggctt ttttattatg tgattttcag tagccagact
      241 tattctatct aatacaagta aagctaagta tttaagattt agcagatgat gaagaaaaga
      301 aaggatggcc taaatatttt aacagattta cgaggctaat catggtataa tatagggtga
      361 tgaaaaattc caacgaggct gagatgaaat tactttatac tgatattcgg acttctttga
      421 cagaaattct aacaagagag gcagaagagc tagttgcagc tggcaagcgg gtcttctaca
      481 ttgcccccaa ctctctttct tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc
      541 aggcttcttt ttcgattacc gtcacgcgct ttgctcaaat ggctcgttat ctggtcttga
      601 atgatttacc agctaaaact actcttgatg atatcggtct tgggttggcc ttttacaaat
      661 gccttgccga actcgatccc aaggacttgc gtgtttatgg cgctattaag caggatcctc
      721 aattgatcca gcagttaatt gagctttacc atgagatgac caaatcccag atgagttttt
      781 tggacttgga gaatttaaca gatgaggata agagggcgga tttactcttg atttttgaga
      841 aagtaacagc ctatcttaat caaggtcagt tagcccaggg aagtcagttg tcccatttga
      901 ttgaggctat tgagaatgac aaggtaagta gtgattttaa tcaaatcacc ttggtcattg
      961 acggctttac tcgtttttct gctgaggaag agcgggttgt ggacttactt cacggcaaag
     1021 gtgttgagat tgttatcggg gcttatgcta gtaagaaagc ctataccagt ccttttagcg
     1081 agggcaatct ctaccaagcc agcgtaaaat ttctccatca tctggcttct aaataccaaa
     1141 cgcctgctca ggactgttct caaactcatg agaagatgga tagttttgac aaggcctctc
     1201 gtttgttgga gtcttcttat gacttttcag aactcgcttt ggatgtcgat gagaaagacc
     1261 gtgaaaattt acaaatctgg tcttgtttga cgcaaaagga ggagttggag ctagtagccc
     1321 gtagtattcg tcagaaatta catgagaact cagacctgag ctacaagcat tttcgtattc
     1381 tcttggggga tgtagcttct taccagttat ctctcaaaac catttttgac cagtatcaga
     1441 ttccttttta tcttggtaga agcgaagcca tggctcatca tcccttgact cagtttgtcg
     1501 agtctatttt agctttaaaa cgttaccgtt ttcgtcagga ggatttgatt aatcttctta
     1561 gaactgattt gtatactgac ctcagtcagt ctgatattga tgcttttgag caatatatcc
     1621 gctatcttgg tatcaatggc ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg
     1681 gaaaatttaa tcttgagcgt ttgaatgtcc tccgcctgag aattttagca cctcttgaaa
     1741 ccctctttgc cagccgaaaa caaaaggctg aaaacctcct acaaaaatgg agtgtctttc
     1801 taaaagaagg agctgtgacc aagcagttac aagatttgac aaccactttg gaagctgtag
     1861 aacaggaaag acaagccgaa gtttggaagg ctttctgcca tgttttagaa caatttgcga
     1921 ctgtttttgc tggttcacag gttagtctgg aagacttcct agccttgctc cattctggaa
     1981 tgagtttgtc ccaataccgt accattccag caacagtgga cactgttctg gtgcagagtt
     2041 acgatttgat tgcaccattg actgctgact ttgtctatgc tattggacta actcaggaca
     2101 atttaccaaa aatttctcaa aacaccagtc ttctgacaga tgaagaaagg caaaacctaa
     2161 accaagcgac cgaagaaggc gttcaattac tgattgccag cagtgaaaat ctcaagaaaa
     2221 atcgctacac tatgctttcc ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc
     2281 caagcctttt taacgaaagt gaaagtaagg aatctgccta tcttcaagag ttgatccatt
     2341 ttggatttag gcggagagag aagaggatga atcacaaagg actgtctaag gaggatatgg
     2401 ggtcctatca cagtcttttg tctagtctgg ttgcctatca ccagcagggt gagatgagcg
     2461 atactgagca agatttgact tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag
     2521 atctgcaagg tctggaaaat ccagctatcc caaccagtcc aagcagcaag accttagcca
     2581 aggacacctt gcaagctctc tatcctgcca aacaggagtt ttacctgtct acgtcgggtt
     2641 tgacagagtt ttatcgcaat gaatacagtt atttcctacg ctacgtttta ggcttgcagg
     2701 aggaattacg tttgcgtcct gatgcccgta gtcacgggaa tttcttgcat cgtatctttg
     2761 aacgcgcctt acagttgcct aatgaagatt cctttgacca acgtctagaa caagctattc
     2821 aagaaaccag tcaagaacgc gaatttgaag ctatttatca agaaagtttg gaagcccagt
     2881 ttaccaagga agttttgctt gatgttgcac ggacgactgg acatattctc cgacacaatc
     2941 cagccatcga aaccatcaaa gaagaagcaa attttggtgg aaaagaccaa gcctttattc
     3001 aattagacaa tggacgcagt gtctttgtac gaggcaaggt ggaccggatt gaccgtttga
     3061 aagctaatgg agcgatagga gtagtagact acaaatccag tctgactcag ttccagtttc
     3121 ctcatttctt taatgggctc aattctcagt taccaaccta tcttgctgcc ctaaaaagag
     3181 aagggaagca gaactttttc ggcgccatgt acttggaaat ggctgaacct gtccaatctc
     3241 tgatggcggt aaaaagtctg gcaggagcag tggtagaagc cagcaaatct atgaaatacc
     3301 aagggctctt cttggaaaaa gaaagcagtt atttaggcga attttataac aaaaacaagg
     3361 ctaatcaact gacagatgag gaatttcagc tcctactgga ctacaatgcc tatctttaca
     3421 agaaagctgc tgagaagatt ttagcaggcc ggttcgccat caatccttat actgaaaatg
     3481 gcagaagcat tgccccatac gtccagcaac atcaggctat tacaggcttt gaagccaatt
     3541 accatctggg ccaagcccgt ttcctagaaa aattggacct agctgatggc aagcgtctgg
     3601 tcggagaaaa actcaagcaa gcttggtttg aaaaaataag agaggagtta aatcgatgaa
     3661 gcttattccc tttttaagtg aggaggagat tcaaaaactg caagaagcag aagcaaattc
     3721 gagcaaggaa cagaagaaaa ctgccgaaca aatcgaagct atctacactt ctggtcagaa
     3781 tatcctggtc tcagcatcgg ctggttctgg aaagaccttt gtcatggcag agcgcattct
     3841 ggaccaattg gcgcgtggtg tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa
     3901 ggctgcaact gaacttaaag aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac
     3961 agatgatgtc gatctcaaac aacacttggg tcgccagttg gcagacctac ccaacgctgc
     4021 catcggaacc atggactctt tcacacaaaa attccttggc aaacatggtt atctgcttga
     4081 tattgcacct aatttccgta ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga
     4141 agtctttcat gaggtctttg aagcgcatta ccaaggtaaa cagaaagaga gctttagtca
     4201 tttgctgaaa aactttgctg ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta
     4261 taaaatctat gacttcctcc aatccaccag taatcctcaa aagtggctga gtgaatcttt
     4321 cctcaaaggc tttgagaaag ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat
     4381 caaacaagcc ctctgggatt tggaaagctt tttccgttac catctggata acgatgccaa
     4441 ggagtttgca aaggctgcct atttagaaaa tgttcagtta attctggatg aaattggctc
     4501 cctaaatcag gagttcgata gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat
     4561 ctctaaggag aaaaacggtc gtgctctgac taatgccagc cgtaaggctg atttgaagcc
     4621 cctggctgat gcctacaacg aagagagaaa gacccagttt actaaactag gacaattatc
     4681 agaccagata gcgattctcg actatcaaga acgttatcat ggagacactt ggaaactagc
     4741 taaaaccttc caatctttca tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca
     4801 ggaaaatgcc tttgaattcg ctgatatcag ccattacacc attgagattt tagaaaattt
     4861 cccacaagtt cgtgagtctt atcaggagcg cttccatgaa gtcatggtcg atgagtatca
     4921 ggataccaac catattcaag aacggatgct ggaattgttg tctaatggcc acaatcgctt
     4981 tatggtggga gatatcaagc aatccatcta tcgtttccgt caggcagacc cgcagatttt
     5041 caatgagaaa ttccaacgct atgcgcaaaa tccccaagaa ggcaagctca ttctcctcaa
     5101 ggaaaatttc cgtagtagtt cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct
     5161 catggaccaa gaggtcggcg aaatcaacta tgataacaag caccagcttg tttttgccaa
     5221 taccaaactg actcccaatc cagacaacaa ggcagaattt ctcctctacg acaaggacga
     5281 tacaggtgag gaagaagaga gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt
     5341 tatcaaggag attctgaaac ttcatcaaga aaaaggtgtt gcctttaagg aaattgccct
     5401 tctgacctcc agccgcagtc gtaatgacca gattctcctc gccctgtctg agtacgggat
     5461 tcctgtcaaa actgacggag agcaaaacaa ttatctccaa tccctagaag tgcaagtcat
     5521 gctagacact cttcgtgtca ttcacaatcc cctgcaagac tatgccttgg ttgcccttat
     5581 gaagtctcca atgtttggtt ttgatgagga tgagctagca cgtttgtccc ttcagaaagc
     5641 agaggataaa gtccacgaaa atctctatga gaaactggtc aatgcacaaa aaatggcaag
     5701 tagtcaaaaa ggcttgattc acacagctct agctgaaaaa ctaaagcaat tcatggatat
     5761 cctagcttct tggcgcttgt atgccaaaac ccactctctc tatgacttga tttggaagat
     5821 ttacaacgac cgtttttatt atgactatgt tggggctttg ccgaatggtc ctgctaggca
     5881 ggccaatctc tatgccctag cactgcgtgc tgatcaattt gaaaagagca atttcaaagg
     5941 tttgtcgcgt tttattcgta tgattgacca agtcttagaa gcccagcacg atttggcaag
     6001 cgtggccgtc gcaccgccaa aagatgcagt agagctcatg accatccaca agagtaaagg
     6061 gctggagttt ccttacgtct ttatcctcaa tatggatcaa gatttcaaca agcaagactc
     6121 tatgtcagaa gtcattctca gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat
     6181 ggagacaggg gcagtagaag accactatcc taaaaccatc aaactctcca ttcctagtct
     6241 gacctatagg cagaacgaag aggaattaca gctagcaagc tattctgagc agatgcgttt
     6301 gctgtatgtt gctatgacgc gggctgagaa aaagctctat cttgtcggca agggttctcg
     6361 tgaaaagctg gaagtcaagc aatacccagc agccaaaaat gggaaactaa atagcaatac
     6421 tagactgcaa gcacggaatt tccaagattg gctttgggct atcagtaaag tgtttactaa
     6481 ggacaagctc aactttagtt atcgttttat tggcgaagat cagttgacca gagaagctat
     6541 cggagagttg gaaaccaaga gtcctctcca agatagctcc caagcagaca atcgtcagtc
     6601 agataccatc aaagaagctc tggaaatgct gaaggaggtg gaagtttata atactcttca
     6661 ccgcgcagct attgaacttc ctagtgttca aaccccaagt caaatcaaga aattctacga
     6721 accagttatg gatatggaag gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa
     6781 aatcagcttc gatttgccag atttttcaac caaagaaaag gtaactggag ctgagattgg
     6841 tagtgctact cacgaactca tgcagagaat tgacctcagc cagcaactaa cccttgctag
     6901 cctaacagaa acactcaaac aagttcaaac tagccaagct gtcagagaca agatcaatct
     6961 tgataaaatt cttgctttct ttgacacagt actcggtcag gaaattcttg ctaataccga
     7021 ccatctctat cgcgagcaac ctttctccat gctcaaacga gaccaaaaga gtcaggaaga
     7081 ctttgttgtc cgtggtatcc ttgatggcta tctgctttac gaaaacaaaa ttgttctgtt
     7141 cgactacaag acagaccgct atgatgaacc aagtcaactc gtagaccgct atcgtggtca
     7201 gttagctcta tacgaagagg ctttatcacg agcctattcg attgaaaata ttgaaaaata
     7261 cttgatttta ctcggtaaag acgaggttca agttgtaaaa gtataactta tactctttga
     7321 aaatctcttc aaaccacgtc agcttcgcct tgctgtatat atggttactg acttcgtcag
     7381 ttctatccac aacctcaaaa cagtgttttg agctgacttc gtcagttcta tctacaacct
     7441 caaaacagtg ttttgagctg attgcggcta gctttctagt ttgctctttg atttttattg
     7501 agtattagaa aggagacctc atgacacttc cagttagaaa atccctgcac gatgcagttt
     7561 tacaggcttc gaaagcggat acttgggaac aagctaccaa ggaatggaat gaagtttcct
     7621 tgatttttaa cggtatcggc cgtagcaatt gtgtctgtgg aaatgccatc aaatacgctt
     7681 atgaactctt taacggtgtc acaggccaac gcctctttcc aattggtagc gactgtgttc
     7741 gtcattttca tcgattgtcc cttgaccagc aattggaaga ggaagaaaaa ctgctcagaa
     7801 aggttgaaaa tctaaccaga aaagctcaga aaaaggaaaa aatcaaggtc aataaaagtg
     7861 actttgacga gcgacttcta aaatggctct gggaaaaagg tgttttcaaa cccaatcgtg
     7921 gcaatcaatt tgcgcctgag agagactacc agcttttact agaagtcttt cagggaggaa
     7981 gttggaccaa ggcggaacca aagaaaaagg ctcggatgga agaagtcctt gaaaagtgta
     8041 tcaaaccctt tttacttggg aaatcggatg accaactcta ccttgtcaag ctaggcaagg
     8101 agaaaattga ctacgaacaa gaactccgta tccaggcaga gaaagaacgc aagaagaggg
     8161 ataaaatcgc caagcaatat gcagacaatc tggttctagc catgggaccc gcagagcgtg
     8221 cttatcaaga ttactttggc tttacagaga ccctgactca agaagaacgc aagtgggaaa
     8281 aaattctttt tggtaaaaat agagcagaac gggctatcaa ggccaaacaa taccaaaaag
     8341 agctggaaaa agaccaacga attgccagtc aggatccaat tgaaagaaaa cagaagcaga
     8401 cttggctcct caattcctat tttcgtgagc ttcctgaaga aaaagctcga ttttctaggc
     8461 tcttattaga atatcgaaaa agtggtgaag tacccttttc aactgaatac ctgtccgatc
     8521 atctcatcga ctttttctat aaaatgaaag cctttgaatt tgaaatcgca ccagaacaag
     8581 tccgagattt tctaaaaaaa agcctgcagg aagaccatcg ctcatcagca caaggaagct
     8641 ggatagaagg aattctcctc aactgcctca aaccattttt agaacgatta gtgatatgag
     8701 taacacctac cgtgtaaatt tcatggtagg tgttattgta cccccaaata atataaaaca
     8761 aagtatgaaa gcgcatctca attttaagac ttttttgtaa attaa
//
LOCUS       DAVLTG010000069         8460 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLTG010000069 DAVLTG010000000
VERSION     DAVLTG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.070"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            174..599
                     /gene="lacA"
                     /locus_tag="VYN12_001856"
     CDS             174..599
                     /gene="lacA"
                     /locus_tag="VYN12_001856"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1416172.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            630..1145
                     /gene="lacB"
                     /locus_tag="VYN12_001857"
     CDS             630..1145
                     /gene="lacB"
                     /locus_tag="VYN12_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1416173.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQIDANFFTEF
                     LEKWDRGEYHD"
     gene            1156..2085
                     /locus_tag="VYN12_001858"
     CDS             1156..2085
                     /locus_tag="VYN12_001858"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1416174.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2087..3067
                     /gene="lacD"
                     /locus_tag="VYN12_001859"
     CDS             2087..3067
                     /gene="lacD"
                     /locus_tag="VYN12_001859"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1416175.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3301..4137
                     /locus_tag="VYN12_001860"
     CDS             3301..4137
                     /locus_tag="VYN12_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1416176.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4173..4490
                     /locus_tag="VYN12_001861"
     CDS             4173..4490
                     /locus_tag="VYN12_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1416177.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            4492..6186
                     /locus_tag="VYN12_001862"
     CDS             4492..6186
                     /locus_tag="VYN12_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1416178.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6401..7807
                     /gene="lacG"
                     /locus_tag="VYN12_001863"
     CDS             6401..7807
                     /gene="lacG"
                     /locus_tag="VYN12_001863"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1416179.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDAPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            7897..8109
                     /locus_tag="VYN12_001864"
     CDS             7897..8109
                     /locus_tag="VYN12_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1416180.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
BASE COUNT         2723 a         1422 c         1734 g         2581 t
ORIGIN      
        1 agatagaagt tttataaaaa agtaaaaaat aaataacaaa aacaaacaca aactgttgac
       61 ttcttcaaac aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac
      121 agccaataca ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta
      181 ttgttatcgg tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag
      241 aaaaagaaaa cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga
      301 ctctcgctgt tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg
      361 cttatggagc tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag
      421 tttctgatga acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta
      481 tgggtgcaca acttgttggt gatgaattgg ctaaaaacat cgctaaagga tttgttaatg
      541 gtaaatacga cggtggtcgt caccaaatcc gggttgacat gttgaacaaa atgggctaat
      601 tagattatag taagaaaggt aagttaaaaa tgagaattgc aattggatgt gaccacatcg
      661 taacagatga aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg
      721 actttggtac atatgaccat acacgtactc actacccaat ctttggtaaa aaagtagggg
      781 aagctgtaac tagcggtcaa gctgatcttg gagtatgtat ctgtggtact ggtgttggta
      841 tcaacaacgc tgtaaataaa gttccaggtg ttcgttctgc cttggttcgt gatatgacaa
      901 cagcccttta tgctaaagaa caattgaacg ctaacgttat tggttttggt ggtaagatta
      961 ctggtgaatt gcttatgtgt gatatcatcg aagctttcat ccatgctgaa tacaaaccaa
     1021 ctgaagaaaa caaaaaattg attgcgaaaa ttgaacatgt tgaaagtcac aatgctcaac
     1081 aaatagacgc aaacttcttc actgaattcc ttgaaaaatg ggatcgcgga gaataccacg
     1141 actaagaggt aacctatgat tttaacagtt acaatgaacc catccattga tatttcctat
     1201 cccttggatg agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct
     1261 ggtggtaagg gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct
     1321 actggtttag tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta
     1381 aagaaagatt tcttctcaat tcagggagaa actcgtaact gtatcgctat tctccacgga
     1441 gacaaccaaa cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagac
     1501 tttttggaac atttcaaaaa actcttggag tcagttgaag tagtggccat ctcaggtagt
     1561 ctgccagctg gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct
     1621 ggcaagcctg tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc
     1681 cataaaccaa cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa
     1741 gtttctgagg atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt
     1801 gaatggatta tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc
     1861 tacaaggtag atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact
     1921 gtggcaggaa tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcatcaag
     1981 gcaaatgtcc ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc
     2041 aactatcaag ttctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga
     2101 acaaaaacgt gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc
     2161 atttgaccaa cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac
     2221 tgtggcccaa atggaagaac ttaaagtctt ggtagcagat gaattgacta aatacgcttc
     2281 atctatgctt cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc
     2341 tggtcttctc cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc
     2401 agactgcttg gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa
     2461 attcttgctt tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta
     2521 catcgaacgc atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaattct
     2581 tgcttacgat gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag taaaaccaca
     2641 caaagttatc ggcgctatga aagtcttttc agacccacgc tttaacattg atgtcttgaa
     2701 agttgaagtt cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta
     2761 tacacgtgaa gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata
     2821 catctacttg agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca
     2881 tgaatcaggt gcaaacttta acggagttct ttgtggccgt gcaacatggg ctggatcagt
     2941 tgaagcatac atcaaagatg gtgaaacagc agctcgcgaa tggcttcgca caactggatt
     3001 tgaaaacatt gatgagctca acaaagttct tcaaacaaca gcaacttcat ggaaagaacg
     3061 tgtgtaagaa agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt
     3121 atgtaaaggt ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg
     3181 tgagtgttac taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc
     3241 tagttcattt gtggtcattt tttgtactca tataccttta agatataaaa ggaggttgac
     3301 atgtatcgaa ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga
     3361 gaagaggtga ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt
     3421 gctgaaaatc aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt
     3481 atggctcttc tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat
     3541 aagctatcaa agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat
     3601 catatttact gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca
     3661 gatatttctg ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac
     3721 tgtcagaagc tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc
     3781 attaatgctg aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa
     3841 attctcagga atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat
     3901 aaccatttct atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga
     3961 tctagagatg ataaccaatc acttctggat atggaagatc atattaaaca atcctatcca
     4021 aaagccttcg agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat
     4081 ttgtataaaa gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa
     4141 tttatttaaa actatataag gagaattcta tcatgaatag agaagaagta acattgttag
     4201 gttttgaaat cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg
     4261 ctgctgaagc tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta
     4321 ttgcagaggc tcaccacgcg caaacaagtc tattgactaa ggaagcttct ggtgaggact
     4381 tagcgtatag tgtgaccatg atgcatggtc aagatcactt gatgacaact atcttgttaa
     4441 aagacctaat gcaccattta attgaacttt acaagagagg agttaaataa aatggataag
     4501 ttaataattt ttattgagaa aggaaagcct ttctttgaga aattatcgag aaatatatac
     4561 ttaagagcga taaaagatgg ttttatttcc agtatgccag cagtattatt ctcaagtatt
     4621 tttatactaa tagctgctgt gcccaatatt tttgggttta aatggtctga tgaacagtta
     4681 gcttttattt tgaaacctta caactactca atggggattt tagctctctt agtagctggg
     4741 acaactgcaa aatcgttaac agattcagtt aatacacgta gtatggagaa aaccaaccaa
     4801 atcaactaca tgtcaacttt tttagcagct gttgttggat tgttaatact ggcagctgat
     4861 ccaattgaag gtggatttgc taatggtctt ttaggtacta gaggattact tactgcattt
     4921 ttggcagctt ttattacagt aaatatctat aaagtatgta ttaaaaataa tgtaaccatt
     4981 agacttcctg aagaggttcc accaaatatt gcacaagttt ttaaagatgt tattccgttt
     5041 gccttatctg ttctttcaat atatggattg gatttaattg ttagaaatat ttttggtaca
     5101 aatgtagcag aatctgttgg taaaatatta gcccctctat tttcagctac tgatggttat
     5161 atcggtttag ctattgtatt tggtgcttat gctttctttt ggtttgttgg aattcatggg
     5221 ccatctgttg tagaaccttt aattgtagct atcagttatg caaatataga agctaatgtt
     5281 cagcttgtgc aagctggtat gcacgcagat aaaattttaa atccagttac tcaaactttt
     5341 gttgtaacaa tgggtggtac tggtgcaaca ctagtagttc catttatgtt tatgtggtta
     5401 tgtaaatcaa aaagaaatag aattgtcgga cgtgcgtctg tagttcctac tttctttggc
     5461 gtaaatgaac caatcctatt tggtgctcca attgttttaa atcctatctt ctttattccg
     5521 tttgttactg ctcctattat caatgtttgg attatgaaat tttttgtaga tgttctacaa
     5581 atgaatagtt tcagtattat tttaccttgg acaacacctg ctccaattgg tattgttatg
     5641 ggaacggcgc tggctccatt gtcattcgtc ttggctataa ctttaatcat tatcgacact
     5701 ttaatctatt atccatttgt taaagtttat gaccatcaaa ttttagaaga agaacggaaa
     5761 ggaaactctt catctgaatt gaaagaaaaa gttgctgcaa acttcaacac tgcaaaagcg
     5821 gatgctattc ttgaaaaagc aggtgtcgat gcagcacaaa ataccatcac tgaagaaaca
     5881 aatgtcctcg ttctctgtgc tggtggaggt acaagtggac tccttgcaaa tgctttgaat
     5941 aaggcagcag cagaatacaa tgtccctgtg aaagcagcag caggcggcta tggtgctcac
     6001 cgtgaaatgt taccagagtt tgatttggtt atccttgctc ctcaagttgc ttcaaacttt
     6061 gaagatatga aggcagaaac agataagctc ggtattaaac tagcgaaaac agaaggcgct
     6121 caatacatca aattaactcg tgatggaaaa ggtgccctag cattcgtaca agaacaattc
     6181 gattaaggct aggaactgtg aaacagtctc ctatcgttac ggaaatcgct atggcgaatt
     6241 tcctaatcgc cttattaatt cgtcggtaaa aagatatcgt ttttacctcc tcatgtcaca
     6301 attcggtgac ttggtacaag aagtgagatg gagaaggatg gctcactgac tcctctcctc
     6361 tcacttttac tttatttaaa tcaagaaata ggtgaaaaaa atgacaaaaa cacttccaaa
     6421 agactttatt tttggtggcg caacagctgc ctatcaagca gaaggtgcta cacatactga
     6481 tggtaaagga ccagtagcgt gggataaata tcttgaagat aactactggt acactgcaga
     6541 accagccagt gatttttaca atcgatatcc agttgatctc aagctagcag aagagtatgg
     6601 tgtcaatggc attcgaattt ctattgcctg gtcacgtatt ttcccgactg gttatggtca
     6661 agtaaatgct aaaggtgttg agttttatca taatttattt gcagagtgtc acaaacgtca
     6721 tgttgagccc tttgtaactc ttcatcactt tgacgcgcca gaagctctcc actcaaatgg
     6781 agacttctta aaccgtgaaa atatcgaaca ttttgtagac tacgctgcct tctgttttga
     6841 agaatttcca gaagtaaact attggacaac cttcaatgaa attggaccaa tcggtgatgg
     6901 tcaatatttg gttgggaaat tccctccagg tatccagtac gaccttgcca aagtctttca
     6961 atcacaccac aatatgatgg tgtctcatgc atgcgcggta aaattgtaca aagagaaagg
     7021 ctataaaggg gaaattggtg ttgttcacgc cctgcctact aaatatcctc tagatcctga
     7081 aaatccagca gatgttcgtg cagcagagtt ggaagatatc atccacaata aattcatctt
     7141 agacgcaact tatctaggtc gctattcagc tgaaaccatg gaaggtgtca accatatctt
     7201 atcagtcaat ggtggtagtt tggatcttcg tgaagaagat tttacagcat tagaagctgc
     7261 aaaagacttg aatgatttcc taggaatcaa ctactatatg agtgactgga tggaagcctt
     7321 tgatggagaa actgaaatta tccataatgg taaaggtgaa aaaggaagct ctaagtatca
     7381 aatcaaaggt attggtcgtc gtgtagctcc tgactatgta tcacgcacgg attgggattg
     7441 gattatctac cctcaaggtt tgtatgacca aatcatgcgt gtgaagaaag attatcctaa
     7501 ctacaagaag atttacatca ctgaaaatgg tctcggctat aaagatgagt tcgttgataa
     7561 cactgtttac gatgatggtc gtattgatta cgtgaaacaa cacttggaga tcttgtctga
     7621 tgcgattgca gatggagcta atgtaaaagg ttacttcatt tggtcattaa tggatgtctt
     7681 ctcatggtca aacggttatg agaaacgtta tggtctcttc tacgtagatt ttgaaactca
     7741 agaacgttat cctaagaaat cagctcactg gtacaagaaa gtagcggaaa ctcagattat
     7801 agactagtag aattagtcat tagatataga attttagtga gtcaaaaaga tgttcaaaga
     7861 ttttatccaa tctatttatg aaaaaaagtt tatattataa atttcgaaaa atgctctcaa
     7921 ataccgtgtt tgacgagtga agaattgaaa agtcttggaa aatggtatgt ctcgactggt
     7981 aaagaatgga tttgtcattc agatgatgag ctggaagaat ttaaaaatct atttttaaat
     8041 tttatcaatc ctgaagaatg ggatactatc tcctttgatt cagattttat gccgtttcaa
     8101 caatcgtaac caatttctca aaaaagttaa atcttatatt tagtactctg taaaactctt
     8161 atctaatcac gttgcttata ctcaatgaaa atcaaagagc aactttaaac taggaagcga
     8221 gtcgcagatt tctcaatgca tagctttgag gaattgggca aaaagtcttt gatatagaaa
     8281 aaagcatagt atcaggtgtt gaaacacctg atactatgct ttttattgtg ggaagattta
     8341 ctttttttct tctgaaattg agttgttacc caggctcttt cagtttatta aggcttgatg
     8401 actttaatgt gtttagatag cttaaaaagg attgaatcac ttagtttaga atctgaaaca
//
LOCUS       DAVLTG010000070         8387 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLTG010000070 DAVLTG010000000
VERSION     DAVLTG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.071"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            120..983
                     /locus_tag="VYN12_001865"
     CDS             120..983
                     /locus_tag="VYN12_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1416181.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIQAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELGTV"
     gene            1366..1986
                     /locus_tag="VYN12_001866"
     CDS             1366..1986
                     /locus_tag="VYN12_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416182.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2072..2515
                     /gene="tsaE"
                     /locus_tag="VYN12_001867"
     CDS             2072..2515
                     /gene="tsaE"
                     /locus_tag="VYN12_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1416183.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2505..3023
                     /locus_tag="VYN12_001868"
     CDS             2505..3023
                     /locus_tag="VYN12_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1416184.1"
                     /translation="MEYELLIREAEPKDAAELVTFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            3031..4047
                     /locus_tag="VYN12_001869"
     CDS             3031..4047
                     /locus_tag="VYN12_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1416185.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4132..5388
                     /locus_tag="VYN12_001870"
     CDS             4132..5388
                     /locus_tag="VYN12_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1416186.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5443..6609
                     /gene="recA"
                     /locus_tag="VYN12_001871"
     CDS             5443..6609
                     /gene="recA"
                     /locus_tag="VYN12_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1416187.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6916..8286
                     /locus_tag="VYN12_001872"
     CDS             6916..8286
                     /locus_tag="VYN12_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1416188.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2537 a         1422 c         1839 g         2589 t
ORIGIN      
        1 tgtaattttt gacttttttt agtttattac cataaagaat tatttatttc tttaacttgc
       61 tattttgaac taaaaatttt ataatgcaat taagcaaata ggaaggttta ttatctttaa
      121 tgagtacact cgcagagaaa ttcagattga aaagaaaaga gttgagactc tcccaacaaa
      181 ctcttgcaga aggaatttgt gaacaaagcc agattagtaa aattgagaga gggcatttca
      241 ttccctccgc agaccttttg ttcaaactct ctcaacgact tgaagtacca ttagattatt
      301 tttttaatga acaaattgaa attaaatcta acctctctaa tttcaagcaa ttgtctgctc
      361 gactattaga cgatagaaat tatgacgatt tggaatatat ttatagaata gagattgaac
      421 gaagtacttt tctaacacta gaagaccgaa cttaccttga atggattcaa gctattattg
      481 acttctatca atatgacagt aagtgtgagg caatttcttc attggaaaat atattattaa
      541 aagtctcttc aaatactctg atttatttaa aggcgttgaa tactctatct aatttctatt
      601 ccttagtggg tcgtgaacaa gaatatgagg caaactactc tcatttaata gagttgtatc
      661 agacaaaaaa tttggaccat caagagtttt tatttggcta catcagagtt cgttacaact
      721 acgctcacta cctagtatca aaggaaaaat ataatgaagc catccaagaa gctcttgaaa
      781 cgattgaact ctgtaaacaa agacagacaa gctaccaatt ggctcctcta cttattcttg
      841 taggaaatgc tggagccaaa tttctagaca gagaacaagt caaaaattat tatatagaag
      901 caagagagtt atgtaagatt tataacaatc ctttaatgtt gatgaagata gaaaattatt
      961 tgaaggaact aggtactgtt tagttaatct tgacattata atttttctga aacgttaaat
     1021 aacctgtaag gctgatagtt agattaatac tatcagcctt ataattatgt gactctgagt
     1081 ccgtctcgct ccgtgaggtg cgagacaaaa caaccacccg tttgacggat tttcatgatt
     1141 tcaaatttat attcttcgaa aatctcttca aatcacgtca gctctatctg caatctcaaa
     1201 acactgtttt gagcaacctg tggctagcta cctagtttga tctttgattt tcattgagta
     1261 ttagtctcta gtgtttgttt agcgtcttaa agagacattt gagaagatta gaaacagttc
     1321 tctcttttct cctagtataa tgattggtag gaagggagag agaagatgaa atcaatgaga
     1381 atcttatttt tgttagcttt aattcaaatc agtttgagta gctgtttcct atggaaggaa
     1441 tgcatcttgt cctttaaaca aagtacagct tttttcatcg gaagcatggt tttcgtttca
     1501 ggaatctgtg ctggagtaaa ttatctttat acccgtaagc aagaagtcca tagtgtccta
     1561 gccagtaaga agtcggtgaa gcttttttac agtatgttac tcttaattaa tttgttagga
     1621 gctgttcttg ttttgtcaga taacttgttc atcaaaaata cgctgcagca agaattagtt
     1681 gactttttat tgccatcctt ctttttccta tttgggctag atttgctgat ttttttaccc
     1741 ttgaaaaaat acgtgcgcga ttttcttgct atgctagaca gaaaaaagac agtgttggtg
     1801 actattttag caacacttct tttcttaaga aatccaatga ccattgtctc acttctgatt
     1861 tatactggac tgggcttgtt ttttgcagcc tatcttgtcc caaattcggt taagaaggaa
     1921 gtttcctttt atggtcatat tttccgagat cttgtattgg tcattgttac gctcattttc
     1981 ttttagagaa agcctgtttt ttatggatgt tatgatgata agtttagtag gaaaatagac
     2041 acaaaagaaa agtttttggt ataataagag tatgtacaca aaaaatgaag aagagttgca
     2101 agccttaggg gagcgtttgg gccatctatt agcaaagaat gatgttttaa tcttaactgg
     2161 agaactgggt gcaggtaaaa cgacctttac taaaggactt gcaaaaggat tacagatttc
     2221 tcaaatgatt aaaagtccca cctatactat cgtgagagag tatgaaggtc gacttccact
     2281 ttatcaccta gatgtttatc gtattgaagg agatgctgat tctatcgact tggatgagtt
     2341 tatctttggt ggcggcgtga ctgttattga gtggggaaat ctcttaggag atgccttgcc
     2401 agatgcttat ttagaattgg aaattctaaa agaagcagat ggacgccgtt taaattttca
     2461 ggcaaagggt ttgcgtgctg agaaattgtt agaggagctt caatatggag tatgaattgc
     2521 tcattaggga agcagagccc aaagatgcag ctgaattagt gaccttttta aatcgtgtga
     2581 gtttggagac agactttacc agcctagacg gagatggtat tctcttgact agtgaggaga
     2641 tggaaatatt cctcaacaag caagctagtt cggacaatca gataacctta cttgcattct
     2701 taaatggcaa aattgctggt attgtaaata ttacagctga tcagcgtaag agagtccgtc
     2761 atattggaga tctcttcatt gtgattggaa aaagatattg gaataatggc ttgggaagtt
     2821 tgttgctaga agaagcgata gagtgggcac aagcaagtgg cattctgcgt cgtctccaac
     2881 tgactgtcca aactcgtaat caagcagcag tccatcttta tcaaaagcat ggctttgtca
     2941 ttgaaggtag ccaagagcgt ggggcatata tagaagaagg gaaatttatc gatgtttact
     3001 tgatgggtaa actgatagat tagtagaaat atggttaaaa aaattattgg aatggtgcta
     3061 gctttacttt ctgtaactgt agtaggagta ggtgtttttg cttatactat ttatcaacaa
     3121 gggacagaaa ccttagctaa aacctataaa aaaatcggcg aagaaaccaa ggttattgaa
     3181 gcgactgaac ctctaaccat tctgttaatg ggagtggaca ccggaaatgc tgaacgaact
     3241 gaaacttggg tcggtagaag tgatagcatg atcttgatga cagtgaatcc taaaacgaaa
     3301 aaaacaacaa tgatgagttt agagcgggat attctgacgc gcattgaatc agggaatggt
     3361 caggctcatg aagcgaaact gaactcagca tatgcagatg gtggagcaga gcttgctata
     3421 gaaaccattc aaaaaatgat gaatatccat attgatcgct atgtgatggt caatatgaga
     3481 gggttgcaaa aactagtgga tgcagtagga ggtattacag tcaataatat cctaggtttc
     3541 ccaatttcta tcagtgacca agaagaattt aatactattt ctatcggtgt tggggagcaa
     3601 catattgggg gagaagaagc cctagtctat gcacgaatgc gttaccaaga tcctgagggg
     3661 gattatggtc gtcaaaaacg tcaacgtgaa gttattcaaa aagtcatgga aaaagctctc
     3721 agtttaaata gcgttggtca ttatcaagag attctaaaag ctttgagtga caatatgcag
     3781 accaatattg atttgtctgc aaaaagtatc cctaacttgc taggctataa agattcattt
     3841 aaaaccattg aaactcagca gttgcagggt gaaggagaga tacttcaagg tgtttcttac
     3901 cagattgttt cgagagcaca tatgttggaa atgcaaaata tactccgacg ttctttggga
     3961 caagaagaag ttactcagct tgaaaccaat gcggttttat ttgaagattt atttggcaga
     4021 gcacctgttg gtgatgaaga taattaactt ttgatacaaa taaaaaaatc aatcgtagga
     4081 aaattcctgc gattttttca aaaaaatacg aatagatagg taggaggaaa catgaaagca
     4141 gaaatcattg ctgttggaac agagattttg acaggacaga ttgtcaacac caatgcccag
     4201 tttttgtcgg aaaaactagc tgagattggg gtagatgtat attttcagac ggctgtagga
     4261 gacaatgaag ttcgtctctt gtctttgctt gagattgcca gtcaacgtag cagtctggtg
     4321 attttgacag gcggtttggg gccaactgag gacgacctaa ccaaacaaac cctagctaaa
     4381 tttttaggga aagcattagt ctttgatcct caggctcagg agaagttgga tatctttttt
     4441 gccctgcgac cagactatgc ccgaacacca aataacgaaa gacaagctca aattgtagaa
     4501 ggagcgattc cactgccaaa cgaaacagga ctggctgttg gaggaaaatt agaagtagac
     4561 ggagtgacct atgtcgtcct tccaggtccg ccaagtgaat tgaaacccat ggtcttaaac
     4621 caacttctac ccaagttgat gacagggagc aagctgtatt cccgagttct tcgtttcttt
     4681 gggattggcg agagccagtt ggttacgatt ttggctgatt taattgataa tcagatcgat
     4741 cctaccttgg ccccttatgc caagacagga gaagtcactc tacgtctgtc aacaaaggct
     4801 agcagtcaag aagaggcgaa tcaagcgctg gatatcttgg aaaatcaaat cttggactgc
     4861 cagactttcg aaggaatttc tttacgagac ttttgctatg gttatgggga agaaactagt
     4921 ttagccagca ttgtggtaga agaactgaaa aggcaaggga aaaccatcgc ggctgcagag
     4981 agtttgacgg caggtctttt ccaagctacc gtggcgaatt tttctggagt ttcaagtata
     5041 tttgagggtg gttttgtgac ctatagcttg gaggaaaaat caaggatgtt ggatattcct
     5101 gccaagaatt tggaagaaca tggtgtggtg tctgaattta cagctcagaa gatggctgag
     5161 caggcacgaa gcaagaccca gtctgatttt ggaattagtt tgactggagt ggcaggacca
     5221 gatagcctag aaggacaccc agttgggaca gtcttcatag gcttggcgca agatcaagga
     5281 actgaggtta tcaaggttaa tattggaggc agaagccgag cagatgtacg tcacattgcg
     5341 gttatgcatg cctttaacct agttcgcaag gctttattaa gtgactaact tttgatataa
     5401 tagtagatag gtctgaggat cattagaatg taggagaata gaatggcgaa aaaaccaaaa
     5461 aaattagaag aaatttcaaa aaaatttggg gcagaacgtg aaaaggcctt gaatgacgct
     5521 cttaaattga ttgagaaaga ctttggtaaa ggatcaatca tgcgtttggg tgaacgtgcg
     5581 gagcaaaagg tgcaagtgat gagctcaggt tctttagctc ttgacattgc ccttggctca
     5641 ggtggttatc ctaagggacg tatcatcgaa atctatggcc cagagtcatc tggtaagaca
     5701 acggttgccc ttcatgcagt tgcacaagcg caaaaagaag gtgggattgc tgcctttatc
     5761 gatgcggaac atgcccttga tccagcttat gctgcggccc ttggtgtcaa tattgacgaa
     5821 ttgctcttgt ctcaaccaga ctcaggagag caaggtcttg agattgcggg aaaattgatt
     5881 gactcaggtg cagttgatct tgtcgtagtc gactcagttg ctgcccttgt tcctcgtgcg
     5941 gaaattgatg gagatatcgg agatagccat gttggtttgc aggctcgtat gatgagccag
     6001 gccatgcgta aacttggcgc ctctatcaat aaaaccaaaa caattgccat ttttatcaac
     6061 caattgcgtg aaaaagttgg agtgatgttt ggaaatccag aaacaacacc gggcggacgt
     6121 gctttgaaat tctatgcttc agtccgcttg gatgttcgtg gtaatacaca aattaaggga
     6181 actggtgatc aaaaagaaac caatgtcggt aaagaaacta agattaaggt tgtaaaaaat
     6241 aaggtagctc caccgtttaa ggaagccgta gttgaaatta tgtacggaga aggaatttct
     6301 aagactggtg agcttttgaa gattgcaagc gatttggata ttatcaaaaa agcaggggct
     6361 tggtattctt acaaagatga aaaaattggg caaggttctg agaatgctaa gaaatacttg
     6421 gcagagcacc cagaaatctt tgatgaaatt gataagcaag tccgttctaa atttggcttg
     6481 attgatggag aagaagtttc agaacaagat actgaaaaca aaaaagatga gccaaagaaa
     6541 gaagaagcag tgaatgaaga agttacgctt gacttaggcg atgaacttga aatcgaaatt
     6601 gaagaataag ctgttaaagc agtggagaaa tccgctactt tttcgatttt tgattcaagt
     6661 ttttagatta tatatagtag cttgaaataa gatatgaaca actttattag gaaagtcaaa
     6721 ttaatttcta gaaatgtttt agcagctaca gcgtactatt ccaaactcaa ccaactataa
     6781 tagatcgaaa ctagaatagt acacatctac ttctaaaaca ttgttaaaaa tcgatttgac
     6841 tgtccttatt tcattccgct atatataagt ttgctgtttc ttgtcgctcc tctggaaagc
     6901 tgatataata gctttatgaa taaaaaacga acagtggacc tgatacatgg tccgattctt
     6961 ccctcgctct taagcttcac ctttccaatc ttgctatcaa atatttttca acagctctat
     7021 aacactgctg atgtcttgat tgttggacga tttcttggtc aagaatcctt ggctgcagta
     7081 ggagcgacga cagcgatttt tgacctgatt gtaggtttta cacttggtgt tggcaatggc
     7141 atggggattg tcattgctcg ttattatggg gctcggaatt tcactaaaat caaggaagca
     7201 gtagcagcca cctggatttt aggtgctctt ttgagcattc tagttatgtt gctgggcttt
     7261 cttggcttgt atcctctctt gcaatactta gatactcctg cagaaattct tcctcaatct
     7321 tatcaatata tttctatgat tgtgacctgt gtaggtgtca gctttgctta taatcttttt
     7381 gcaggcttgt tgcggtctat tggtgacagt ctagcagccc tgggatttct gattttctct
     7441 gccttggtta atgtggttct ggatctctat tttattacgc aattgcatct gggagttcaa
     7501 tccgcaggac ttgctaccat tatttcgcaa ggtttatcag cggttctctg cttttattat
     7561 attcgtaaaa gtgtgccaga actcttgcca cagtttaaac atttcaaatg ggacaaaagc
     7621 ttgtacgcgg atctcttgga gcaaggtttg gctatgggct tgatgagttc aattgtatct
     7681 atcggtagtg tgattttaca gttttctgtt aatacatttg gtgcagtgat tattagtgcc
     7741 cagacggcag ctcgacgcat tatgaccttt gcccttcttc ctatgaccgc tatttctgca
     7801 tcaatgacga cctttgcttc tcagaatcta ggagctaagc gacctgaccg cattgttcaa
     7861 ggtcttcgaa tcggcagtcg tttaagtata tcctgggcag tttttgtttg tattttcctc
     7921 ttttttgcca gtccagcctt ggtttccttc ttggctagtt cgacagatgg ttacttgata
     7981 gaaaatggaa gtctctatct gcaaatcagt tcagcctttt atcccatttt gagcctcttg
     8041 ttgatttatc gcaattgctt gcagggcttg gggcagaaga tccttcctct agtttctagc
     8101 tttattgaac taatcggaaa aatcgttttt gtggttttga ttattccttg ggcaggatat
     8161 aagggtgtta tcctttgtga acctcttatc tgggttgcca tgacagttca actgtacttc
     8221 tcactattcc gtcatccctt gataaaagaa ggaaaggcaa ttttggcaac caaagtgcaa
     8281 tcctagttgg atttactgaa taaaatccat ttcctctagt gaacatcgaa aaaacttgtg
     8341 ttctcttctt tagtttggtg ttgaaaatag tttaacagac ttttgac
//
LOCUS       DAVLTG010000071         7754 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLTG010000071 DAVLTG010000000
VERSION     DAVLTG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.072"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            62..6496
                     /locus_tag="VYN12_001873"
     CDS             62..6496
                     /locus_tag="VYN12_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1416189.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7128..7604
                     /locus_tag="VYN12_001874"
     CDS             7128..7604
                     /locus_tag="VYN12_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1416190.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7642..>7754
                     /locus_tag="VYN12_001875"
     CDS             7642..>7754
                     /locus_tag="VYN12_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1416191.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAV"
BASE COUNT         3015 a         1077 c         1501 g         2161 t
ORIGIN      
        1 aggctagcaa agttaaagtt tattatctat tggaagttaa ataaatatgt aaggaattaa
       61 aatgaaaaaa agtacagtat tgtcattaac cacagctgca gttattttag cagcctatgc
      121 ccctaatgag gtagtcttag cagacacatc tagctctgaa gatgctttaa acatctctga
      181 taaagaaaaa gtagtattag ataaggaaac agaaaataaa gagaaacatg aagatattca
      241 taatgctata gaaacttcaa aggatactga agaaaagaaa acaacagtta ttgaggaaaa
      301 agaagttgtt agtaaaaatc ctgtgataga cactaaaact agcaatgaag aagcaagaat
      361 caaagaagat tccaatcaat cccaaggaga taatgcacac tcgtctgcaa ataaaggcac
      421 agaaaatccg aaaaaagaag atagacttgt ctatattgct gaatttaaag ataaagaatc
      481 tggagaaaaa gcaatcaagc aactatccaa tcttaagaat acaaaagttt tatatactta
      541 tgatagaatt tttaacggta gtgccataga aacaactcca gataacttgg acaaaattaa
      601 acaaatagaa ggtattacat cggttgaaag ggcacaaaaa gtccaaccca tgatgaatca
      661 tgccagaaag gaaattggag ttgaggaagc tattgattac ctaaagtcta tcaatgctcc
      721 gtttgggaaa aattttgatg gtagaggtat ggtcatttca aatatcgata ctggaacaga
      781 ttatagacat aaggctatga gaatcgatga tgatgccaaa gcctcaatga gatttaaaaa
      841 agaagactta aaaggaactg ataaaaatta ttggttgagt gataaaatcc ctcatgcgtt
      901 caattattat aatggtggca aaatcactgt agaaaaatat gatgatggaa gggattattt
      961 tgacccacat gggatgcata ttgcagggat tcttgctgga aatgatactg aacaagatat
     1021 caaaaacttt aacggcatag atggaattgc acctaatgca caaattttct cttacaaaat
     1081 gtattctgac gcaggatctg ggtttgcggg tgatgaaaca atgtttcatg ctattgaaga
     1141 ttctatcaaa cacaacgttg atgttgtttc ggtatcatct ggttttacag gaacaggtct
     1201 tgtaggtgag aaatattggc aagctattcg ggcattaaga aaagcaggca ttccaatggt
     1261 tgtcgctacg ggtaactatg cgacttctgc ttcaagttct tcatgggatt tagtagcaaa
     1321 taatcatctg aaaatgaccg acactggaaa tgtaacacga actgcagcac atgaggatgc
     1381 gatagcggtc gcttctgcta aaaatcaaac agttgagttt gataaagtta acataggtgg
     1441 agaaagtttt aaatacagaa atataggggc ctttttcgat aagaataaaa tcacaacaaa
     1501 tgaagatgga acaaaagctc ctagtaaatt aaaatttgta tatataggca aggggcaaga
     1561 ccaagatttg ataggtttgg atcttagggg caaaattgca gtaatggata gaatttatac
     1621 aaaggattta aaaaatgctt ttaaaaaagc tatggataag ggtgcacgcg ccattatggt
     1681 tgtaaatact gtaaattact acaatagaga taattggaca gagcttccag ctatgggata
     1741 tgaagcggat gaaggtacta aaagtcaagt gttttcaatt tcaggagatg atggtgtaaa
     1801 gctatggaac atgattaatc ctaataaaaa aactgaagtc aaaagaaata ataaagaaga
     1861 ttttaaagat aaattggagc aatactatcc aattgatatg gaaagtttta attccaacaa
     1921 accgaatgta ggtgacgaaa aagagattga ctttaagttt gcacctgaca cagacaaaga
     1981 actctataaa gaagatatca tcgttccagc aggatctaca tcttgggggc caagaataga
     2041 tttactttta aaacccgatg tttcagcacc tggtaaaaat attaaatcca cgcttaatgt
     2101 tattaatggc aaatcaactt atggctatat gtcaggaact agtatggcga ctccaatcgt
     2161 ggcagcttct actgttttga ttagaccgaa attaaaggaa atgcttgaaa gacctgtatt
     2221 gaaaaatctt aagggagatg acaaaataga tcttacaagt cttacaaaaa ttgccctaca
     2281 aaatactgcg cgacctatga tggatgcaac ttcttggaaa gaaaaaagtc aatactttgc
     2341 atcacctaga caacagggag caggcctaat taatgtggcc aatgctttga gaaatgaagt
     2401 tgtagcaact ttcaaaaaca cggattctaa aggtttggta aactcatatg gttccatttc
     2461 tcttaaagaa ataaaaggtg ataaaaaata ctttacaatc aagcttcaca atacatcaaa
     2521 cagacctttg acttttaaag tttcagcatc agcgataact acagattctc taactgacag
     2581 attaaaactt gatgaaacat ataaagatga aaaatctcca gatggtaagc aaattgttcc
     2641 agaaattcac ccagaaaaag tcaaaggagc aaatatcaca tttgagcatg atactttcac
     2701 tataggcgca aattctagct ttgatttgaa tgcggttata aatgttggag aggccaaaaa
     2761 caaaaataaa tttgtagaat catttattca ttttgagtca gtggaagaaa tggaagctct
     2821 aaactccaac gggaagaaaa taaacttcca accttctttg tcgatgcctc taatgggatt
     2881 tgctgggaat tggaaccacg aaccaatcct tgataaatgg gcttgggaag aagggtcaag
     2941 atcaaaaaca ctgggaggtt atgatgatga tggtaaaccg aaaattccag gaaccttaaa
     3001 taagggaatt ggtggagaac atggtataga taaatttaat ccagcaggag ttatacaaaa
     3061 tagaaaagat aaaaatacaa catccctgga tcaaaatcca gaattatttg ctttcaataa
     3121 ccaagggatc aacgctccat catcaagtgg ttctaagatt gctaacattt atcctttaga
     3181 ttcaaatgga aatcctcaag atgctcaact tgaaagagga ttaacacctt ctccacttgt
     3241 attaagaagt gcagaagaag gattgatttc aatagtaaat acaaataaag agggagaaaa
     3301 tcaaagagac ttaaaagtca tttcgagaga acactttatt agaggaattt taaattctaa
     3361 aagcaatgat gcaaagggaa tcaaatcatc taaactaaaa gtttggggtg acttgaagtg
     3421 ggatggactc atctataatc ctagaggtag agaagaaaat gcaccagaaa gtaaggataa
     3481 tcaagatcct gctactaaga taagaggtca atttgaaccg attgcagaag gtcaatattt
     3541 ctataaattt aaatatagat taactaaaga ttacccatgg caggtttcct atattcctgt
     3601 aaaaattgat aacaccgccc ctaagattgt ttcggttgat ttttcaaatc ctgaaaaaat
     3661 taagttgatt acaaaggata cttatcataa ggtaaaagat cagtataaga atgaaacgct
     3721 attcgcgaga gatcaaaaag aacatcctga aaaatttgac gagattgcga acgaagtttg
     3781 gtatgctggc gccgctcttg ttaatgaaga tggagaggtt gaaaaaaatc ttgaagtaac
     3841 ttacgcaggt gagggtcaag gaagaaatag aaaacttgat aaagacggaa ataccattta
     3901 tgaaattaaa ggtgcgggag atttaagggg aaaaatcatt gaagtcattg cattagatgg
     3961 ttctagcaat ttcacaaaga ttcatagaat taaatttgct aatcaggctg atgaaaaggg
     4021 gatgatttcc tattatctag tagatcctga tcaagattca tctaaatatc aaaagcttgg
     4081 cgagattgca gaatctaaat ttaaaaattt aggaaatgga aaagagggta gtctaaaaaa
     4141 agatacaact ggggtagaac atcatcatca agaaaatgaa gagtctatta aagaaaaatc
     4201 tagttttact attgatagaa atatttcaac aattagagac tttgaaaata aagacttaaa
     4261 gaaactcatt aaaaagaaat ttagagaagt tgatgatttt acaagtgaaa ctggtaagag
     4321 aatagaggaa tacgattata aatacgatga taagggaaat attattgctt atgacgatgg
     4381 tagtgcctta caatatgaaa ctgaaaaact tgacgaaata aaatcaaaaa tttatggcgt
     4441 tctaagccca tctaaagatg gacactttga aattcttgga aagataagca atgtttctaa
     4501 aaatgccaag gtatattatg gaaatagcta taaatcgata gaaatcaaag cgactaagta
     4561 tgactcacat tcaaaaacga tgacatttga tttatacgct aatattaatg atattgtgga
     4621 tggattagct tttgctggag atatgcggtt ttttgttaaa gatgataatc gaataaaagc
     4681 tgaaactaaa attagaatgc ctgaaaaaaa taaggaaact aaagcagaat atccctatgt
     4741 atcaagttat gggaatgtaa tcgaattagg agaaggagat ctttcaaaga acaaaccaga
     4801 caatttaact aaaatggaat ctggtaaaat ctattctgat tcagaaaaac aacaatatct
     4861 gttaaaggat aacatcattc taagaaaagg ctatgcacta aaagtgacta cctataatcc
     4921 tggaaaaacg gatatgttag aaggaaatgg agtctatagc aaggaagata tagcaaaaat
     4981 acaaaaggcc aatcctaatc taagagtcct ttcagaaaca acaatttatg ctgatagtag
     5041 aaatgttgaa gatggaagaa gtacccaagc tgtattaatg tcggctttgg acggctttaa
     5101 cattataagg tatcaagtgt ttacatttaa aatgaacgat aaaggggaag ctatcgataa
     5161 agacggaaat cttgtgacag attcttctaa acttgtatta tttggtaagg atgataaaga
     5221 atacactgga gaggataagt ccaatgtaga agctataaaa gaagatggct ccatgttatt
     5281 tattgatacc aaaccagtaa acctttcaat ggataagaac tactttaatc catctaaatc
     5341 taataaaatt tatgtacgaa atccagaatt ttatttaaga ggtaagattt ctgataaggg
     5401 tggttttaac tgggaattga gagttaatga atcggttgta gataattatt taatctacgg
     5461 agatttacac attgataaca ctagagattt taatattaag ctgaatgtta aagacggtga
     5521 catcatggac tggggaatga aagactataa agcaaacgga tttccagata aggtaacaga
     5581 tatggatgga aatgtttatc ttcaaactgg ctatagcgat ttgaatgcta aagcagttgg
     5641 agtccactat cagtttttat atgataatgt taaacccgaa gtaaacattg atcctaaggg
     5701 aaatactagt atcgaatatg ctgatggaaa atctgtagtc tttaacatca atgataaaag
     5761 aaataatgga ttcgatggtg agattcaaga acaacatatt tatgtaaatg gaaaagaata
     5821 tacatcattt gatgatatta aacaaataac agacaagaca ctaaacatta agattgttgt
     5881 aaaagatttt gcaagaaata caaccgtaaa agaattcatt ttaaataaag atacgggaga
     5941 ggtaagtgaa ttaaaacctc atagggtaac tgtgaccatt caaaatggaa aagaaatgag
     6001 ttcaacgata gtgtcggaag aagattttat tttacctgtt tataagggtg aattagaaaa
     6061 aggataccaa tttgatggtt gggaaatttc tggtttcgaa ggtaaaaaag acgctggcta
     6121 tgttattaat ctatcaaaag atacctttat aaaacctgta ttcaagaaaa tagaggagaa
     6181 aaaggaggaa gaaaataaac ctacttttga tgtatcgaaa aagaaagata acccacaagt
     6241 aaaccatagt caattaaatg aaagtcacag aaaagaggat ttacaaagag aagatcattc
     6301 acaaaaatct gattcaacta aggatgttac agctacagtt cttgataaaa acaatatcag
     6361 tagtaaatca actactaaca atcctaataa gttgccaaaa actggaacag caagcggagc
     6421 ccagacacta ttagctgccg gaataatgtt tatagtagga atttttcttg gattgaagaa
     6481 aaaaaatcaa gattaagaca aaagctatag aaaaaaatgg tttatgtact gagattagat
     6541 agtgaggtga tgacatagtt ttgtgaaaac ggccatttat aactcaatta tttagtttac
     6601 ttcacttcac tattgatact atttggagtt attaatggac ttagtttaga taactaatga
     6661 attgattgaa agggttagta ttgacaatat tggtcatatt gattagaaaa tagagtctat
     6721 caaaatttaa aggctaatag aggtgatgag acaatttcaa ggaattaagt agcgtttggt
     6781 tgcttaattc ctttttattt ggaaggaagt ttttcgtaac cgcccaataa cgaagtctat
     6841 tggacggtta cgatatgatc actgacttcg tcagtcttat ctacaacctc aaaactgtgt
     6901 tttgagcaac ctgcggctag cttcctagtt tactctttga ttttcattga gtattagaac
     6961 agaaaaaatg cttggagtat ttgtttgtgt gtttattttt atataacaaa ctataaacaa
     7021 aacaaaaata taaaaaaaga gacaaaaaag aacaaatagt aattgacaac ggtttcatat
     7081 agtgttatac ttatggcata aagttaatgg aaagaaggga aaaacttatg gtattagatt
     7141 atttctttga caaaaacctt gtgttttgct tagaagcgga taatcaagaa catctctttg
     7201 atcaggttgc aactttattg gaagaacgag aaattgtaac tccaacttat cgtgaagcct
     7261 tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact
     7321 tgccaaatgt agcgattcct cacacagata ttgttcataa tctagctgag aaagtggtgg
     7381 ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat aaggaagtag
     7441 aagtatctct actcttcttt atcattaaca attcaagttc aagtcaaacg aacattctgg
     7501 ctcagttgat ggactttttc acaggaaatg gtcatcttga agacctatca aaaatttctg
     7561 aaccagaaaa actttatgct tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa
     7621 ataaaatcgg aggaaatcca aatgattaaa attcttgctg cctgcggtgc aggtgttaac
     7681 tcaagtcacc aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt
     7741 cactgtgatg cagt
//
LOCUS       DAVLTG010000072         7517 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLTG010000072 DAVLTG010000000
VERSION     DAVLTG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.073"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(96..1511)
                     /locus_tag="VYN12_001876"
     CDS             complement(96..1511)
                     /locus_tag="VYN12_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1416192.1"
                     /translation="MTIFPDDFLWGGAVAASQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     EYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1524..3362)
                     /locus_tag="VYN12_001877"
     CDS             complement(1524..3362)
                     /locus_tag="VYN12_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1416193.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3380..4219)
                     /locus_tag="VYN12_001878"
     CDS             complement(3380..4219)
                     /locus_tag="VYN12_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1416194.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4519..7302)
                     /locus_tag="VYN12_001879"
                     /pseudo
     CDS             complement(4519..7302)
                     /locus_tag="VYN12_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2479 a         1571 c         1042 g         2425 t
ORIGIN      
        1 agaggtttag aatttgatgt cttccaaacc tctttatttc atatttaatg agatgttgcc
       61 ttaaccgtga taatatctaa tcatcaataa acaaactatt tgaataagga ttctccattt
      121 gattcaatca ctcctttata ccaagtaaag gacattttct tatatcgatt gaatgtgcca
      181 tttccatcat catttcgatc aacataaatg agaccgtacc tcttagaaag ctgtgcagtg
      241 gacatagaaa cgcagtcaat acatccccaa gacgtatagc ccataatttc cacaccatct
      301 tgtagagctt cagctacttg caataaatgt tctttcatat actgaattct ataatcatct
      361 tggactgtta agttattaaa ttcatctttt attagttgat ctttagcacc taatccgttt
      421 tccactataa ataatggaat ttgataacgg tcataatatc tatttaaaat tatacgtagt
      481 ccaattggat caatttgcca tccccactca gaagactcta aataaggatt tactaagcca
      541 ccaataatat tcccttctcc tgaattatac tgtgttggaa gagcagactg agtcacactc
      601 atgtaatagc taaaggataa aaaatctacg gtataatttt ttaataactc tgcatcttca
      661 gctgcaaact ctatgttaat gtcatgttcc ttaaaatatc tttttgcata attcggataa
      721 taacctctaa catgcacatc tgaaaataga taatttagat tctcatactc atgagtcgcc
      781 catacatctt ttggatttgg agtcattgga taagctggca tagctaatac catacacccc
      841 accttaaact ctgaattaat ctcacgagca atttttgtaa ccaaactcga ggcgactaat
      901 tcatgatgta tagcttgata taattcttgt ttcgaaagat tctccttagg tatatctatt
      961 cctccactag taaatggtaa ttccaaaaca gagtttactt cgttaaatgt aagccaatat
     1021 ttaactttat ctttatacct ttctaaaact gttcgagcaa atttttcata aaaatgaatc
     1081 attctcctat caacccatcc atgatatttt cttgctaaat ataatggagt ctcatagtgt
     1141 gaaagagtta caagtggctc tatcccgtga gcatgtagtt catcaaacaa ttcatcataa
     1201 tattccaaac cagcttcgtt aggttcttct tcatctcctt ttggaaaaat tctactccat
     1261 gcaatagaag tacgaaaaac attaaagccc atttcagaaa acaaggatat atcttcctta
     1321 tatttatgat aaaaatcaat acctaacaat tttaagttat cttctgtagg attttctgtt
     1381 gcttctccta atccaccttt gggtaacaca tcctgaactg ataatccctt accatcttca
     1441 ttatatgctc cctctacttg actagctgca acagctccac cccaaagaaa atcatctgga
     1501 aaaatggtca taactttcct ccattataat attaccagta attccttaga atgctcgatt
     1561 gtctgattat taggtaatac taatacatct agaaaatcat tggtattcgt tacaattact
     1621 ggtgtaactg tttcgtagcc tttagtcttg attaaattca agtccatttc aaaaatcaac
     1681 tgatttttga aaactctgtc tccttcttct acatgactaa taaaaccttg accttttagc
     1741 tcaacagtat ctaatccaat atgaattagt aactcaacac cctcatcact cttcaatcca
     1801 attgcgtgct tagtcggaaa aatatttgta attttcccat caaatggtgc ataaacctta
     1861 ccttcacttg ggataatcgc tactccgtct ccaattagtt tatctgaaaa tgttttatcc
     1921 tggacatcgc ttaacggaat gatttctcct gatataggag aaaatatcat ttttttattt
     1981 gaaactccaa cttcaacttc taaattgcta gaactctctt cttcatcgat tccaaatata
     2041 taagctaata caaaggtaat aacaaccgaa atgaccgcca caattaaagc atttacaata
     2101 tttgatggca catcagaata aataaattga ggcaacgcta tcaaagatgg gacagcaaat
     2161 agatacgctt taacactagt aagacctgca aataatcccg ctaatccacc accaatcata
     2221 gctgcataaa gcggtttttt atattttaaa gtcacaccat ataatgcagg ttcggtaatc
     2281 cctgcaagta aggctgagaa acctgctgca aaagcaattt gttttgtatt attattttta
     2341 ctctttaatg caacagccat cgaagcagcc ccttgagcta agtttgaccc taacattgct
     2401 ggaagaatta atacgtctgg agtagcaata gatgccgcca aaaaaatagg tgcaaaagcc
     2461 caatgcattc cagtcataac aataaatggc ataatagcac caagaatagc taatgtaagc
     2521 catccagcta caccatacat ttgcccaact agatttgata atccttcacc aacaattact
     2581 ccaataggcc cgactacaac taaggcaata cagcttgata ctaataatac tagcgtaggt
     2641 tgcaaaaaac tcttagtaac agctggtgtt aatttagcaa tcattttttc aatatatttc
     2701 atcaaccaaa ccataataag aattggaacg actgacgaac cataactagc tggtgtcaca
     2761 ggtacaccaa ataaactaag aggattccct gattgcacca tttgaacaaa atttggatgg
     2821 agaagtacac ctgctacaga catagctaat gtagatgtta cttttaattt ttgtgatgca
     2881 gaataagcta ataacagcgg taagaaataa tatggagcat ccccaaaaaa tgtcaaaaaa
     2941 gcaatagtct gagaatctga ttgcaatata ccaagcattg gtaaaataat taccaagact
     3001 ttcagcatac ctccccctaa cattgctgga atgattggag tcatggaacc agcgatatac
     3061 tcaatgattc tttctaaaat attccctttg tgcccttgaa caactgaatc ggattcaaaa
     3121 ttgccaagtt taacgaattc tttataataa ttagctacat cattaccaag tataatttga
     3181 tattgtccat tctttttcat aatacctatt acacctggta tcttcttcac atcatcatca
     3241 ttgactaaat tttcatcttt taattctaat cttaaacgtg ttacacaatg ggtaactcta
     3301 ttgacatttt tttcacctcc aattacatcg aggatttttt gtaccgtatc tttataactc
     3361 atggtattct cctattctat taatctaaat tttttgttaa gcgacgaata tgagccatca
     3421 aataaactaa ttcactagaa gtcagcaaat aattgtactc cgtttgtata aacattgcca
     3481 cctgttcacc acattcatat tctctaggat atttattttt cattaatgct aacaagtctt
     3541 catcatcatc gtcacaataa gttgtatttt caaccaagcg atgggcaaat aattttatat
     3601 gagttatgaa tctataataa tcaatagaat cttggttaaa ctcagtacaa tagaaatctt
     3661 gaatgatttt ctcaattccc ataattattt cagtgatttt atacgactct tgaaaattat
     3721 tttctaaatt agcattaaca aaatgtagcg ctatgaatgc agcttcgtca attggaagtt
     3781 caatacctaa ctcttttttt attatttgta aagccctttt cccaagttca aattcttctt
     3841 tataatattt cgatatttcc cagcgtaggg gattcgaaat aataatccct tctttataac
     3901 gttctatgct cgaagaaata tgatccgtta aattaatata gataatttca tcaaaattat
     3961 tacccaatgt tattttacct aggttaatta ttttttcggt gatgtacacc aactccaaag
     4021 gaacgttaat aaacatctct gtaaaacggg tcatattatc tctatttttg agaaaaaaac
     4081 ttttctcaat atcaattgga tttactttat ctccagtttt tcttccaaaa gctattcccc
     4141 ttccaaaaag aagaatatcg atatcttttt tactttgcgc aattacggca ttgtggttta
     4201 gtattcgttt tatgatcata aaatttccct tttaaaataa aaggaaccta cttaaaaaca
     4261 tcaagaaact tcttctgatg tgattaaata ggttcctgct cacttgtatt agtgataaca
     4321 tccttttatt tcaattttta atggtgacat gaagcttaaa taattaataa ctctgtaacc
     4381 gtttttattt tatgatattt caatctattt gtcaagtact tataaaaatt tttttatttt
     4441 gtgtgattcg aatgtgataa tggcaacagt ctcactaaag aaatgaaaat catacataga
     4501 aatttttaaa aattttctct atcgtaaacc tgccactagt tcagaaacta tactagctga
     4561 ttccaaacgt aatatggtca tctcatctac cttccctaat aatggcattg caccatacca
     4621 aacaatagtc ttattcacca aaagaatagg cgttactatt tttgattgag taaaagacac
     4681 tttaattttc tggctcttca actggtctag ccatgcttta tttgcaaccg tctctggtat
     4741 acatatctca atttgactaa tcctaaattc ttttagaaaa ttcatcagtt ttgtctggtg
     4801 cacataaggt aaaataagca gacattcctg tctttcccct gctaagtcct ctctcaacac
     4861 cttctcatat ctactatcaa cataaacgaa ttgtttctcc tcaccctcga tgacacgata
     4921 atccatcttt cgataagcta cttgtcgttt ctgaaacatc ttttctaaat aaggaacatg
     4981 aatatccaca taatcgaaaa tacgcaccaa agacttatcc ttgtagtttc tatgaatccg
     5041 acctgcatac tgaattaaat tatttttcca agaaaagggt gctgccaaga taagcgtgtc
     5101 caactgaggt aagtcaaaac cttcgccaat gtattttcca gtagacaaca aaacaaaccc
     5161 tttatctaac tgttctaacg tctccagtaa actcgttctt tctcggactt tggtttttcc
     5221 gctaataatg taacagccat caacctcttt ctctttcaat aacttttcaa agacatctat
     5281 ctgttgaatt cgattaacta aaaccaagat attccgtcct tctgccactt gggctagaat
     5341 atccttgaga atcaactgat tcctcgctga gtctgtagca atccaatcac tgagctgtat
     5401 aaaattactt gctttggtct tttcaatctc caaatgacca aaagaagtga atcttaattg
     5461 caattgccgt ttaaaatccg tttccctctt atcagcagta tggagtatct caccaattct
     5521 ctgaaaaaca ataggctcat gaccattctt acgctcaggc gtagccgtca aaccgtaaag
     5581 atacttccct ctaaactgag caacaacttt ttcaaacatc aaggcagaga catgatgaca
     5641 ctcatccaca atcatcatct catactcatc caaaagactt tgactatttt ccaacttaaa
     5701 tagagattga atcataacga catcaaccag tttactcagc catttcttag tcccaccgta
     5761 ctgtccaaca tagccgatta ccttttcacg acctgatgcc gtataacgga tagcctcctc
     5821 ctcttcgaaa gtcaaaaagc agtttaagcg atctagccat tggtctaaga gttgcttatt
     5881 atggactaga ataattgttt ttgttttccg ttcagagata agagcagcac ctaaaacggt
     5941 cttcccaaaa ccagtctccg catgaagtaa accattttct ttagaattca tatctgacag
     6001 ggctaattct tgctccaaag taagctctcc cttaaatgct actctaatag acctttgtac
     6061 ttttctccta tcctccacaa ctacctgctt aaatttatct tgcaatggat ataacaagcc
     6121 tcttggcagc cataaataat aatcggattc tccaaataaa tacattcgct caggaatttg
     6181 ataggttggc tgtcgcatag cctgctttaa atatagtaaa atgaaataat aacaggacaa
     6241 atcgatcagg aaagtcaaat cgatttctaa caatgtttta gaagcagagg tgtactattc
     6301 tagtttcaat ccactataaa attcgggatt agaaaaggaa gccatatttt tcaagaaaaa
     6361 aagtgccttg gatgtcacag acgatttttc aagttggatc atattggata aaacgacctt
     6421 caactcctta tccaattctt gcttgcctaa ctcctcttgg attaacagtg ccactttagc
     6481 agttgaaatc ctctgaattt cttgtagata cctccattga tcttcataag gctgaaaatg
     6541 ttcatccaca aagaccgttc gcccttgatg ataagcttct ccttgaaaag gaagggaaat
     6601 taaattatca aatccacctt taggaagaac atcctgattt ggaaacatgc catcaaaaga
     6661 atcaaaggac agttgcatac tttcctgcat agccaattct aatagtttct ttccaaacag
     6721 gcgagccttt cgactcagaa tcgcttcctc aaagaagaac caaatatgga gtccgtaacc
     6781 cgaacgagaa atctctaaat gggcttccat ctggcgttcc ctggctattc ttcgaatggt
     6841 taaaccagct tctttccaat ctccttcatc aaaatccagt accaaaaaat gacagctatc
     6901 atctaagtgc ataggaaaga taccgatagc tgcctcccca cgaaaatgag atttcaaaac
     6961 ggagttcgtc aatgtctgga aactccgttt ttcaggtggc aactgcttcc aaccataatc
     7021 ataggaagga aaatactgaa ttttcccttg ttcattgata aaattcttag cataaacatc
     7081 ataacgtcca gcaaacacgg aggtaaacaa ttgtaatttt tcttgcgtcg tcaagcgact
     7141 actttgaagt tggaacatct cctcgaactg agagcgttcc ataacaaact gactcttgtc
     7201 tttaagacgt ttacacaaga aaaactcact atccccatta aaagaagaaa agacatcaag
     7261 tacttctacc acaattccat ccaaagacac aaaaacagcc ataagagtca cctccttgat
     7321 tcctataggc tgattataac aagaatagct gaaattgtac acgaaaataa aatcctaata
     7381 gtactcattt tgtatgtggc taatattccg tctcgctccg gaatgtacga ggtaaataga
     7441 gtttaaacga gcagtctata aaattcaaaa aacgcatcat atcaggtgta catgaactac
     7501 accccaaaag ttagaca
//
LOCUS       DAVLTG010000073         7451 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLTG010000073 DAVLTG010000000
VERSION     DAVLTG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.074"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(36..1739)
                     /gene="ilvD"
                     /locus_tag="VYN12_001880"
     CDS             complement(36..1739)
                     /gene="ilvD"
                     /locus_tag="VYN12_001880"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1416195.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1972..2904)
                     /locus_tag="VYN12_001881"
     CDS             complement(1972..2904)
                     /locus_tag="VYN12_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1416196.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2901..3758)
                     /locus_tag="VYN12_001882"
     CDS             complement(2901..3758)
                     /locus_tag="VYN12_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1416197.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRLTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3762..5108)
                     /locus_tag="VYN12_001883"
     CDS             complement(3762..5108)
                     /locus_tag="VYN12_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1416198.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5121..5405)
                     /locus_tag="VYN12_001884"
     CDS             complement(5121..5405)
                     /locus_tag="VYN12_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1416199.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5409..7439)
                     /locus_tag="VYN12_001885"
     CDS             complement(5409..7439)
                     /locus_tag="VYN12_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1416200.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
BASE COUNT         2400 a         1640 c         1147 g         2264 t
ORIGIN      
        1 gttgacgtga tttgaagaga ttttcaagta tgagtttatt ttttacctga cttgtccata
       61 ttccagaagt ctgtcacggc tccgcgtgaa gcagatgata cgatatgggc atatttaccg
      121 aggacaccac ggctgtaaag tggtggcaag gttgtttctg ccttgcgttt ttcaagttct
      181 tcttcggata cggccatgga aatttctttg gtatcttggt caaccgtaac gatatcgccg
      241 gtacggagat aggcaattgg tccaccatcc tgagcttcag gagcgatatg tccaacaacc
      301 agaccataag taccaccaga gaaacgtccg tccgtcaaga gggccacctt atctccctga
      361 cctttaccaa caatcattga agaaagtgac agcatctcag gcataccagg accaccttta
      421 ggtccaacaa aacgaacaac gactacatcg ccatcaacga tttcatctgt cagaacggcc
      481 tgaatcgcat cttcttctga gtcaaagacc ttagctggcc caacgtgacg acgcacttta
      541 acacctgata ccttggcaac tgcaccgtca ggagcaaggt tcccgttcaa gatgataagc
      601 ggaccatccg cacgttttgg attttcaagt ggcatgataa ctttttggcc tggagtcaag
      661 tctgcaaagt cagccaagtt ttcagctaca gtcttaccag tacatgtgat gcgatctccg
      721 tgaaggaaac catttgccaa caagtacttc ataaccgcag ggacaccacc gacttcgtag
      781 aggtcttgga agacatactg accagatggt ttcaagtcgg ccaagtgagg cacacgttct
      841 tgaatcgtat tgaagtcctc aagtgacaag tcaacatttg cggcatgggc aatggcgagc
      901 aagtgaagag tggcgtttgt agaaccaccg agagccatcg ttacagtaat agcatcttca
      961 aaggcttcac gagtcaagat atctgatggt ttgagaccaa gttccaacat cttaacaaca
     1021 gcacgtcctg ctgcttcgat atcttctttc ttatcagctg attcagctgg gtgagaggat
     1081 gaccctggca aactcatccc tagaacttcg atagcagttg ccatggtatt agcagtatac
     1141 ataccaccac aaccaccagg gccagggcag gcattacatt caagacgttt cacgtcctca
     1201 gctgtcatgt caccgtggtt ccattttccg ataccttcaa agacagaaac caagtcgata
     1261 tctttaccat caagatttcc cggtgcaata gttccaccat aggcgaaaat agctgggata
     1321 tccatattag caatagcaat catagatcca ggcatgttct tgtcacagcc accgatagcg
     1381 acgaaggcat ccacgttgtg accactcata gccgcctcga tggagtccgc gatgatgtca
     1441 cgagatgtta gagagaaacg cataccaggc gttcccatag cgatcccgtc cgctacggta
     1501 atggttccaa actgtacagg ccaagcgcct gcagatttga caccttcttt agccagtttc
     1561 ccgaaatcat gcaagtgaat gttacatggt gtattttccg cccaagtcga aatcactccc
     1621 acaatcgatg tttcaaagtc cttatctgtc ataccagtcg cacgaagcat agcacggtta
     1681 ggtgatttaa ccatgctgtc atagatgcta ctgcggtgac gtttatctaa ttcagtcatc
     1741 ttatccctcc catttcagtt tttactatta tagcacaatt taaaggcaat gaacagaata
     1801 aaattcttga attttcagaa aattctatac gcatgtgaaa tatttaaaat taaaaacaac
     1861 aaagcggatt agtgcacttt ctgatgacca gaatatgctt tttaatccgc tttctttaaa
     1921 taacgtactg taatttttac agaaattctt tcagataagt gtatttaaca tctatcttgc
     1981 attataaatt tctagaacct tctcttttat attcgattca ctcaaaccat actcattaag
     2041 aagataatcc attttcccta cttgaccaaa tctttcttga acacccatcc gatgaatttt
     2101 tgtcattcca tcatcagaga ataattcaca taaagaactg ccaattccac ctatctgatt
     2161 gtggttttct acagtaaata tagtttttcc acttaacatt gtttttatct gttctggtat
     2221 cggtttgatt ctaaataaat ctatcacact tactgaataa cctaatttag acagttcatc
     2281 tgcaactcga atacttggag caaccattat accagaagca acgattacaa gatcttcacc
     2341 atgccttaac tcaatgtagc ctttagaaaa atcttctcca ccttgataca caggaactgg
     2401 agcttttcta attgttcgaa tatattttag tccttttaag tccaatgtct ggttcaatat
     2461 ttcacgaaat tggatatcat cagttgcttc aaaaatgatc gatttaggaa ttaaacgtaa
     2521 caatccaatt tcttcaaatg gcatatgtgt cccaccattc atttctgcag ttactcctgc
     2581 atctgatcca atcacagtgg catccaattg tgcgtatcca agagaaataa ataattgatc
     2641 aaatactctt cgtgaagcaa aaggaccaaa tgtatgaaga taaggtctaa acccctgaat
     2701 agacaagcct gctgcaaggc cgaccatttc tgcttccata atcccaacat tcacataacg
     2761 gtctccaaag tccttttcaa gattatgagt agccatcgaa cttgacaaat cggcttctaa
     2821 gactactata tcagaataac tttgattagc ctctaaaagg aagtctctat atacatgccg
     2881 taattctttc gtacttctca tcattctgtt tcctccaatt cctgacttaa tctttctaca
     2941 actgaagtta acatttgttt ctcctctaca gtaaggcgaa gatgatgatt ggatttcatt
     3001 tcttccagct cttgaacccc ttgaccttta atagtatcta atacaatgca cttaggtgat
     3061 gaattatttg actgttttaa ttggacaatc ccttcataaa tttctctaat atctgaaccc
     3121 ttgaccctaa tggattcaaa tccaaatgct gaaaattttt ctacgaaatc acctggatta
     3181 caaatatcct ttgtaaaacc atctaattgt tttttgttat catcaacaaa tacaattaag
     3241 ttggataact gttgatgaga agcaaactgt atagcctccc aacattgtcc ctcatttaac
     3301 tcaccatctc caacaatagc ataagtataa aagggactct ttcttattct ctgaccatat
     3361 gcaagtccag ttgcaacact aattccttgt cctaaagagc ccgttgtcat atctatgcct
     3421 ggcgttagat ttctatcagg atgagacggt aatttggttc catttgtatt taaagaatat
     3481 aggaattctt tgtcaaagaa accattcaaa tagagtgtac tgtatagagc tggtcctcca
     3541 tgaccttttg ataatatgaa ataatctcta tctcgtgctg caaatatttc tggagtcatt
     3601 ggcattattt caccataaag cactgctaaa acttctacga tagacagact tcctccgtaa
     3661 tgtccgaatc caagatgatt caatgttcta agagtattta atcggatgtt agtcgcaaat
     3721 tttcttaacc catcttctct atttttactt aaaatcatcc cttattcctc ctttgcagat
     3781 ggctttttaa taaaggatac tccaaacata actgctagaa taagaacaag accaatcaca
     3841 atgcctgctt gtgagccaaa ttgatttaac attcctaaaa taattcctga tagaccaaaa
     3901 tctgcatctg agaaagttga tccttggaaa ccaagtcctc ccaaaactgg cattaaaaag
     3961 actggaagaa aactgattaa aataccttgt aaaaatgctc caatagtggc tccacgaaca
     4021 ccaccagatg cattcccaat gacacctgca gtcgctccac agaagaaatg aggcacaaca
     4081 cctggtaaga taacaaccgt tcctgaagca atcataattg ccatacttac taaaccacca
     4141 acaaaactag agataaatcc aattagaact gcattgggtg cataagtata aacaatcgga
     4201 caatccaaag caggttttga attaggtaca agacgctctg aaataccttt aaaggctgga
     4261 acaatttcac ccaaaataag gcgaacacct gctaaaataa caaatacccc tgctgcaaat
     4321 tgacctgcta attgtaaagc ataaactaga ccacttgtac cactactgat ttctttttct
     4381 atatattctg accctgcaaa gatagctaca ataatgtaaa taactgccat ggataaagtg
     4441 atactaacag tactatcacg taaaaaagct aaactctttg gaaatttaat gtcctctgtt
     4501 gattttgatt tgtcaccgat aaggctacca gtaaaaccac tcaaccaata tcccaaagaa
     4561 ctgaaatgac ctaaagctac cttgtcattt ccagttaatt gaaccatata tttttgcaca
     4621 aatgctgggg aaatactcat aataataccg agtgctaatc ctcctagtaa gatgagaggc
     4681 aagctagtaa agccagcaac tgataaaatg accgcaatca tacatgccat atatagagtg
     4741 tggtgccctg ttaaaaaaat atatttaaat cgagtaaaac gagcgattaa gatattgaac
     4801 accatgcctg caaacataat cattgcagta gctgagccat atgttgttaa agctacagct
     4861 acaattgctt cattattcgg cacaacgcca gataaatgaa aagcatgctc aaacatggta
     4921 ccaaatggat ttaaagaatt ttgtacaatt cctgcaccac cagatacaac taagaaacca
     4981 acaaaggtct taattccacc tttaataata tcaggtaatt tcttcttctg aagaactaat
     5041 cctaagattg caattaaagc tactaaaata gctggtgtac taacaatatc caatatgaac
     5101 ttcatcatga cgctagcctc ctatataagt cctttttctt cacaaagttt agtaattaat
     5161 tctcgtagtt catccatatc aataatacta tttaagatac gaacatctcc aagatgacta
     5221 gctgaatcag ctagatcacg accaacaatc caaatatcag ctgcatttgg atctgctcca
     5281 cctaaatcat aatgttcaac ttctacatcc gaaacattca aatcactcaa tacagattca
     5341 atattcatct gtaccataaa acttgaacct aatcctgaac cacaagctgt accaattttt
     5401 aacattatct aatcctcctg tttaattatc attttaatgt catcatagtt ttttgatgat
     5461 attaaagttt gaacatgatt tttatctctt aaaattgttg ttaaatgtga caaagccttt
     5521 aaatgactct cattatcaat ggctgcaata caaatcaaca atcttacctc ttgttctgga
     5581 ttatccaata aataaatcgg ttcttccaaa actaacattg acattcctat ttcattcaca
     5641 ccttcatctg gccgagcgtg aggaattgct actcccttcc ctaaattaat aaaaggccca
     5701 aactcttcta ctttttgaat cattgcctca gggtagttct cagttatctt atcttgatcc
     5761 aaaagcggtt tagctgctaa acgaatcgcc tccttccatc ctaatttttg cgaactaacc
     5821 tgataggttt ctttggtaat aagttgttct agcactggta caatttcctt tctatcattt
     5881 ttttgataaa gataattctt taacgccaat cttaattcca attcttgtgt aataattcca
     5941 tatcttttga caatattcag gatttgttca atctcaaaat ccccatactc taaattcgga
     6001 aaatctttta acactagttc tactagttgt attgcttgct cttcagtcat cataaccgaa
     6061 actagataat ttggcttttc tgtctccacc tttatggtag aaaaaaccat atcatagtca
     6121 ctactagctt tcacctgtaa atcatcaatc tttgaggttc ctataaactc aatttgagga
     6181 aataatgcta atagattctc ttttaacatc aatgaagaac taacaccatt aggacaaatg
     6241 attgctgctt tataccattt ttgaggcaaa gtatctgctt tctttaaata acctccgaaa
     6301 tggataacaa aatatgctgt ttcactatca ggtatgggat tgtcaatagc gtccatcaag
     6361 ggcatcaaag aatctttgac taattcaaat aaatcaggat aatgttcttt aacatgcaat
     6421 acatattcat ttgaactagg taggccgaac tttaatctat agtaagccgg tataaggtgg
     6481 cgacgaagat tttctctcaa tccttccctt tgtttaaaat gtaacaaaga aatatcttcc
     6541 attctactta taatagcctc tgttaattga ttaaagtaaa ccggagcaac atctacttca
     6601 ccttcaaagc aacttgataa taaaactgtg atatagcgat aatcatcctc agaaaacacc
     6661 gtatctataa ttcccaaatc aaccactgta tccaataaaa tagtcgttat atcttgaata
     6721 acaggagata ctaatgtctc tgaaagacat actctttcaa catccctttg atacctacac
     6781 agaatgaata ctaaaccgaa aaggtaaact tttaattgat taacaatagg tactagctgt
     6841 agcttctcat aataatcttt aactacctga tcaatcaaat cataagttaa tgaatacccc
     6901 caactggata aaacataatc caaaccccaa atccctatgg aggattccag caactcacta
     6961 accatttgaa aagctaagcg gtgcttattc cactctgaac cgtgtaaagt ataacctttt
     7021 gctctactgt accctagctc caaatcatta tctaacataa tctttcttaa tgattgaata
     7081 tcagataagg ttgtattctt acttactttc aaaaagtctt ggtaatgatt attcgatata
     7141 aaatctaatc ggcaaaaagt gtaaagatag attaaagcta agcgagtcga ctttggtaaa
     7201 accaattcat ccgacttaat aatatctgtc aaagactgct tcgtacgatt tgataaacta
     7261 tagcgacctt gctttttatc cagcactatc cctttattag ctaaataagg cactaaataa
     7321 tctattcctt ctttgacttc ctttataggt aagctcacct taacagataa ctcatataat
     7381 gatagctcac aatgatccat caaagtcatc aaaataacta gtgctctata atcaaacatt
     7441 tctcttcctt t
//
LOCUS       DAVLTG010000074         7414 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLTG010000074 DAVLTG010000000
VERSION     DAVLTG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.075"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(153..992)
                     /locus_tag="VYN12_001886"
     CDS             complement(153..992)
                     /locus_tag="VYN12_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1416201.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMSFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(1006..1827)
                     /locus_tag="VYN12_001887"
     CDS             complement(1006..1827)
                     /locus_tag="VYN12_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV1416202.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(1964..2821)
                     /locus_tag="VYN12_001888"
     CDS             complement(1964..2821)
                     /locus_tag="VYN12_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1416203.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(2975..3709)
                     /locus_tag="VYN12_001889"
     CDS             complement(2975..3709)
                     /locus_tag="VYN12_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1416204.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(3709..4392)
                     /locus_tag="VYN12_001890"
     CDS             complement(3709..4392)
                     /locus_tag="VYN12_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1416205.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4582..4812
                     /locus_tag="VYN12_001891"
     CDS             4582..4812
                     /locus_tag="VYN12_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1416206.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            5041..7299
                     /locus_tag="VYN12_001892"
     CDS             5041..7299
                     /locus_tag="VYN12_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1416207.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
BASE COUNT         2304 a         1640 c         1346 g         2124 t
ORIGIN      
        1 cggatgtaaa ccaaatcaac tctaacaaaa atagatttac aagagtaaaa aaacgaacaa
       61 atttagtttc ttagcgagaa gaatactaaa cgttcgtttt ttgtgaatta agaataatga
      121 tacaaattat caatattttt tgtctaacta ttttagacat atcttttcat tactttagga
      181 agacaattac taatctccgt tggcaaaacc acatactgtt cttgagctag ttcttgggct
      241 atggctgaat gaagatgggt cgctactgcc acacgttcgt aaagactagc ttgcttaaac
      301 tggcctgcaa atcctgcaat catcccagca agcgtatctc ccattccccc agtcgcctga
      361 tagggaccgc caacctgtaa ctggtaataa tctgattggc cagcttgcca aatacgagta
      421 gctgaacctt tctccaccaa aattgttcct tgagggaagg aagttagggc actagccgtt
      481 gcatcttcct tttgcttttc aatcgtaatt ccagataatt tttcccattc tttttggtga
      541 ggagttagga taagctggct tgaggaaaat gacaaacttg tcctagcaag aatggtcaag
      601 gcacctccgt ctacaatcaa aatctgattt tgtcttaagc cagcaaagac ctgtttaact
      661 agatcttctc caaaagcatc gtctcgtaaa cccggcccca gcaagacaac ttctgccttc
      721 tccaattgct cttttaacaa ctgctggtct tgaagagaaa aggacatagc ctcaggtaaa
      781 tggctgtgca gggctggaat attttcccta tctgttccaa cggtcaccaa tcctgcaccg
      841 ctttttacag ctgccaaagc agccatgatg atggcaccac cataaggata agttccacca
      901 agaaacagca gacggccata gtctccttta tgactagtac gagaacgttc aataataact
      961 ttttctagta aggcttgatc aatcactttc atcgttcttc ctcaactatc ctttatctga
     1021 ttgttttaaa acaacttgat agactttctt agtccactct tctaagtctt ctccagcata
     1081 gtcaagataa tgcaccctat cttgtatttt agttggaata atattttcaa attggctctt
     1141 attatgagtt ggaataatac aaatatacaa ctcactaaat aaattcaaca tgtccttaat
     1201 ttttgcaaca tggtagccat caaaaatata accagtaact ttaatcaaat ctgtatagat
     1261 aaaatgaaaa ctcactccag gaataaactt gtcttgtaat tctttctctg aaggagctcg
     1321 acctaataaa cgctccatcg ctaatcgata accagaactt gtatttgacc accctaacat
     1381 gacataatca aaataatcta tcggatccga tgcagcattt ctactatcca aaaccaactc
     1441 ttcagcatct cgcctaaagg ctttcacagc agataagagc tgacctgttt taaagataga
     1501 aatcgctgca tctatagtcg tagtatgact acagtagtct gaagtcacta acctcttatg
     1561 tagatcataa gtcgaggcta ctcttttatc tgtaggggta aatggtggca gaaagggatg
     1621 ctgacagatg taatctaaaa tttctttttt taaacaagaa tcagcacact caatacttgt
     1681 ttgacgttta tgaagttttt cgtaagctat aaatttagca attttttcta attcccactc
     1741 ttgaatattt ggataatcaa ttagtgctag gtagtatatt ccatcccatt gtaaactata
     1801 ttccctatta taaattttta aaatcatcta atcacctcac tccattatac aacaaaaagg
     1861 aggcgcagac ctccttttgt aatcttatat ctaaaattta atattcattt ctgccatttt
     1921 aaatatagct atagaaaata cactctcttc agcgattttt ctcttatttt ctatccaatg
     1981 tccgaagtgc tgcttgataa gtttgctcca tcagcatagt aatggtcata gggccgacac
     2041 ctccagggac tggcgtaata tagctagcaa gtggggcaac tgcctcataa tccacatccc
     2101 cacagagctt accattttca tcacgattca tcccaacgtc aatgactacc gcacctggtt
     2161 tgacaaagtc agcagtcaca aacttggcac gaccgattgc gaccaccaga atatctgctt
     2221 tagcagccac cttagcaaga ttatgggtgc gtgagtgggt caaagtcact gttgcattct
     2281 tggccaaaag aagctgagcc atgggttttc caacgatatt agaacgaccg atgacaaccg
     2341 catttttacc ttctaattca atcccatatt catgaaacat ttccataatt cctgcaggtg
     2401 ttgatggaat catgactgga tgtccagacc aaaggcgtcc catatttaga ggatggaaac
     2461 catccacatc cttttctggg tcaatagcca atagaaccgc ctcttcatca atgtgttttg
     2521 gtaatggcaa ctgaaccaaa atcccatgcc aagctggatc ctgattgtat ttagcaatca
     2581 ggtctaacaa ttcctcttga gtaatggtct ctggaactcg cactacttcg ctacgggaac
     2641 cagccgcaag agctgacctc tccttgttgc gaacgtagac ttggctggct ggattatccc
     2701 caaccaaaat cactaccaaa ccaggcacta gagctgtttc ttcctttaat tttgcagtct
     2761 tttcagccaa ctgcccctgc aatttggccg ctaaagcttt cccatcaata atctgtgtca
     2821 tatcacttct cttttctttc aaatatcttc cattatacca aaaactgcta gtgccctcta
     2881 acacttcttt cctaggttat cctatagttt caaactataa gaaaaagctc tggttgaact
     2941 tttcactaat cttgtcttga aattttaaaa tagattataa aaccttactc aagaaatctt
     3001 tagtccgttg ttcttgggtt tgttcaaaaa tctgctcagg tgtcccatct tcaacaacca
     3061 caccgtctgc cataaagata acacgatctg ccacctcacg ggcaaatccc atctcatgtg
     3121 ttacgataac catagtcatc cctgacttgg caaggtcttg cataacagcc aatacctcac
     3181 ctaccatttc aggatccaag gctgaagttg gttcgtcaaa gagcaaaaca tctggttcca
     3241 tagccaaccc acgcgcgatg gcaatccgtt gttgctgccc acccgacaga ctctgtggat
     3301 aagcgtctgc cttatctggc aaaccaactt tttccaaaag ctcttgggct ctcttctcag
     3361 caacttccct gctttcacct ttagtcttga taggtgacaa ggtaatattt tccatcacag
     3421 tcatattagg aaagaggtta aattgttgga aaaccatgcc catcttctca cgcatggcaa
     3481 acaggtcatt cttcttgtcc gtaatatcga ctccctcaaa gataagcttc cccttggttg
     3541 cttcctccaa caaattcata gagcgaagca aggtagattt cccactccct gaaggaccga
     3601 tgataacgac aacttctcct cttttaatct cgaggttgat gcccttcaat acttcattct
     3661 ttccaaaaga tttatgtaaa ttttcaattt ttatcaaggt ttctgtcatt atttcttatc
     3721 tccttgtccc atatgttttt caaaagcttt caaggctact gtcagaatag aggtcataat
     3781 caagtagtaa aatgctgcaa ataaaagtgg tgttaaaggt agataggttg ttgtagaaac
     3841 tgttgtagcc ccattccaca actccatgac cccaatagct gataagaggg agctgtcctt
     3901 gataatggtg ataaattcgt tccccaatgc tggcaagata tttttgactg cttgtggcaa
     3961 aatcacataa cgcatcgcat ttttaagacg aatccctagc gaataagccg cctctagctg
     4021 accttttgga accgcattga ttccggcacg aacagtctcc gaaacataag caccactatt
     4081 catagagata atcaaaatcc ctggaatcag acgcgaaaaa tcaacaccta aaattccaat
     4141 ctgaatagtc ggagcattga tatgcataag agcaaaggca atcataattt gaaccatcat
     4201 cggtgtccca cggaaaatcc aaacgtacaa gttggccaac caaacaagcg gtttaaactt
     4261 tgaacgttgc ccaaaagcca agacaacacc caaaatagtt cccaaaaaga taacacagat
     4321 agaaataaga atcgtcacaa cagccccata gttaaaataa ggtaaatact taggtaaaaa
     4381 agaaaaattc atagtcacac tgctttctaa aatagaatac tgtatgatta taacatgttt
     4441 tgaattaaaa tttaaatttt ttatccaatt tatttaaaaa tctttaaact agcagaatta
     4501 gcgagaaatc ttagtttttt ctagtcaagt tgccctcctt tatggtaaaa tagtaacgat
     4561 aagaaatgaa ggagaatcaa aatggaatca catttggtta gaatcatcaa ccgccttgaa
     4621 gcaatggcaa acgatggcgg aaatttaaaa cgtaattttg aacgcgaagg agttgttgtt
     4681 gcagaagttg cgtacagcca cgacgaagaa aacggcccaa tctttaccct tcgtgacgta
     4741 gaagatcgcg aaacgtatac gtttgatagc attgacttaa tcgcaatgga aatttacgaa
     4801 cttctctact aatctaaaac aagttgggat tgtccctgca tgtctaagta aaatcctttt
     4861 tgtctcacaa ataggatttt tttatagtcc aaattcacaa aaattttcat tgtaacaact
     4921 tctcaaagct tcaatctttt tacttgcttt acaccccaat cctgttataa tgagagtata
     4981 gaatttgact atttttgacc tttaaacaag tcaggctaaa gaaagaaatg aggtagatgt
     5041 atgctttgtc aaaactgtaa aattaacgac tcaacaattc atctttacac caatctcaat
     5101 ggaaaacaaa aacaaattga cctctgtcaa aactgctata agattatcaa aacagatcct
     5161 aacaatagcc tcttcaaagg tatgacggat ctgaacaatc gtgacttcga tccctttggt
     5221 gatttcttca atgatctaaa caatttcaga ccttctagca atactcctcc tattccccca
     5281 acccaatcag gtggaggtta cggtggaaac ggcggttatg gttcccaaaa tcgtggatct
     5341 gctcaaactc cgccacctag ccaagaaaaa ggcctgctgg aagaatttgg tattaatgta
     5401 actgaaattg cccgtcgtgg agacattgac cccgttattg ggcgcgacga tgagattatc
     5461 cgtgtcatcg agattctcaa tcgtagaacc aagaataatc ctgtccttat cggtgaacct
     5521 ggtgtcggaa aaacggccgt tgtcgaaggt ctagctcaga aaattgtcga tggcgatgtg
     5581 ccacataaac tccaaggtaa acaagtcatc cgtctggatg tggttagctt agttcaagga
     5641 acggggattc gaggacaatt tgaagaacgc atgcaaaaac tcatggaaga aattcgcaaa
     5701 cgtgaagaca tcatcctctt tatcgatgaa atccatgaaa ttgttggtgc tggttctgcg
     5761 agtgatggta atatggacgc aggaaatatc ctcaagccag cccttgctcg tggagaactg
     5821 caactagtcg gtgctactac cctcaatgaa taccgtatca ttgaaaagga tgctgccctc
     5881 gagcgtcgta tgcagcctgt taaagtcgat gaaccaacgg tggatgaaac aatcactatt
     5941 ctcaaaggga ttcaaaagaa atacgaagat taccaccacg ttcaatatac cgatgctgcg
     6001 attgaagcag ctgcaactct ttccaatcgc tacatccaag atcgcttctt gcctgacaag
     6061 gccattgacc tcctagatga agctggttct aagatgaact tgaccttgaa ttttgtggat
     6121 cctaaagtaa ttgatcagcg cttgattgag gctgaaaatc tcaagtctca agctacacga
     6181 gaagaagatt ttgagaaggc ggcctacttc cgcgaccaga ttgccaagta taaggaaatg
     6241 caaaagaaaa agatcacaga ccaggatact cctatcatca gcgagaaaac tattgagcac
     6301 attatcgagc agaaaaccaa tatccctgtt ggtgatttga aagagaaaga acaatctcaa
     6361 ctcatccatc tagccgaaga tctcaagtct catgttattg gccaagatga tgcagtcgat
     6421 aagattgcca aggctattcg ccgtaatcgt gtcggacttg gtacccctaa ccgcccaatc
     6481 ggaagcttcc tcttcgttgg accaactggt gtcggtaaga cagaactttc caaacaactg
     6541 gctatcgaac tttttggttc tgctgatagt atgattcgct ttgatatgag tgaatacatg
     6601 gaaaaacata gtgtggctaa gttggtcggc gctcctccag gttatgttgg ctatgatgag
     6661 gctggtcaat taactgaaaa agttcgccac aatccgtatt ctctcatcct tctcgatgaa
     6721 gtggaaaaag ctcacccaga tgttatgcac atgtttcttc aagtcttgga cgatggtcgt
     6781 ttgacagacg ggcaaggacg caccgttagc ttcaaggatg ccatcattat catgacctca
     6841 aatgcaggta caggaaagac cgaagctagc gttggatttg gtgctgctag agaaggacgt
     6901 accaattctg tcctcggtga actcggtaac ttctttagcc cagagtttat gaaccgtttt
     6961 gatggcatta tcgaatttaa ggctctcagc aaggataacc tccttcagat tgtcgagctc
     7021 atgctagcag atgttaacaa gcgcctctct agcaacaaca ttcgtttgga tgtaactgac
     7081 aaggtcaagg aaaagttggt tgacctaggt tatgatccaa aaatgggagc acgcccactt
     7141 cgtcggacta ttcaagacta tattgaggac acaatcactg actactacct tgaaaatcca
     7201 agcgaaaaag atctcaaagc agttatgact agcaagggaa acattcagat taaatctgcc
     7261 aaaaaagctg aagttaaaag ttctgaaaaa gaaaaataaa tcctatagaa aaggagtaga
     7321 aaatgaaatt tttctgcttc tttttttact aaaataactg taatttcttg acagcttgcc
     7381 ctttgtccat tatgatatat agtagactga atct
//
LOCUS       DAVLTG010000075         7025 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLTG010000075 DAVLTG010000000
VERSION     DAVLTG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.076"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(319..1161)
                     /locus_tag="VYN12_001893"
     CDS             complement(319..1161)
                     /locus_tag="VYN12_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1416208.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1237..1314)
                     /locus_tag="VYN12_001894"
                     /pseudo
     CDS             complement(1237..1314)
                     /locus_tag="VYN12_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1417..2808)
                     /locus_tag="VYN12_001895"
     CDS             complement(1417..2808)
                     /locus_tag="VYN12_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1416209.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKMEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEAAILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3043..3420)
                     /locus_tag="VYN12_001896"
                     /pseudo
     CDS             complement(3043..3420)
                     /locus_tag="VYN12_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            3653..4630
                     /locus_tag="VYN12_001897"
     CDS             3653..4630
                     /locus_tag="VYN12_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1416210.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFRKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            4627..5709
                     /locus_tag="VYN12_001898"
     CDS             4627..5709
                     /locus_tag="VYN12_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1416211.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     SEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(5773..6809)
                     /locus_tag="VYN12_001899"
                     /pseudo
     CDS             complement(5773..6809)
                     /locus_tag="VYN12_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2080 a         1540 c         1207 g         2198 t
ORIGIN      
        1 atttatattt tgtatcaaat gatatttgag aaatttcttt caatacaatt acctccttga
       61 taaattctat atagtataaa attcaaaaag aaccaccttt caacacccaa gccttgcgac
      121 taggggcgtc agaaacgcgg ttccacccta atttattact tcattgtttt tgaaaatact
      181 acagaaagcg ccagctcatt attttgccct acttggctcc cactgtccca agctcgcttg
      241 aagaacgcca taagactttc tttcctgctg actattatat caaaaattag aataatgtac
      301 aattcttttt atgattttct agaaatccac atcatcaact cgtggagcac ccgattgaac
      361 agcaatcgtt tttaaggttt ctctctcctc atgactcagt tcaattccaa agcaatcaag
      421 attagcttga atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa
      481 gctccaggcc aaggctatct gagcaacaga ctttccgtga tttgctgcta tttcttggac
      541 ttgcttgcta tcaaacagtt ctccttgtcc aaaaggcccc caagcttcca ataaaattcc
      601 cttttcacga cagtaagcta cgacttcctc ttgatacaca cctggcgcca agcgaacttg
      661 attgaccgca ggaacgatag ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa
      721 attgctaacg ccgatagcac ggattttccc ttcttgatag aggtcttcca tcgctctcca
      781 aacttccgca ttgcgagttt tccatgcgtc attttctctg agcggttttg ggttcggcca
      841 atgaatcaaa tacaaatcca aataatccaa gcccagtttt tctatagatt tttccaaagc
      901 ttgacgagtt tgctcatagg tttgctgact attccaaagc ttggtagtta cgaacatttc
      961 ttcacgtgga actccgctat ctttgattgc ttgaccaaca ctttcttcat tctgataaat
     1021 cgccgccgta tcaatatgac gataaccagc cttcaaggct tctaacactg cacgataggc
     1081 ttcttctcca tccttagcct taaaagttcc aaatcccaat actggaattt ctactccatt
     1141 atttaattga taggtattca tatgcttctc cttctatttt atactctctt caaaccacat
     1201 caacgtcgcc ttgccgtagg tattgttact gacttcgtca gttctatcca caacctcaaa
     1261 acactgtttt gagcaacctg cagctagttt cctagtttgc tctttgattt tcattgagta
     1321 ttattcatca attatagcat aaaacatttt ttaagtagta ctatcttttg taaaaaataa
     1381 gtctatcaca tatctgacag acctattttt tcttgcttat tcatcacgac tataatacag
     1441 ctcatgagct tttaggcgag tattgagcat ctctggtatg gtcacaaagg tataaccttg
     1501 atttttcaaa tactcaatga cccttggcaa ggcattgact gtcggactgt gaatatcatg
     1561 catcaaaacg atagagccgt tagctacttg atgctgaatt tccgtcaaaa tagctgcttc
     1621 atttttactc ttccagtcca gactatccac atcccacata ataaagctca aatcgaggct
     1681 attgcgaata tcatctgtaa tagctccata aggcggacgc atgagtttgg aactagaacc
     1741 cagcacttta gttagcacat cctcagtatc agtaatctgc tttttagctt catcaagaga
     1801 tagttgcgag agaataggat ggctccaact atggtttcca acaacatgac cttcagattt
     1861 tatcctcttc accaagtcct cattcccaga aacatttttc ccaagcacaa agaaagtcgc
     1921 tttaatatca tatttagcta gggtctctaa tacctgcggg gtcgttgctg gatttggacc
     1981 atcatcaaag gttagagcga caactttttg atgtttctta tcaaagtaag attggtacaa
     2041 ggccgcatct ttttcgagta agtacgaaga ttggataaca tcaaagaaag cagatactgg
     2101 caaggctatc tcttctaaat tttcaaccac aggacttgga taaaggataa tctgactatc
     2161 cttgtaatca aaattccatg cagacaagtc ttggtcagag aagtttttta caatctgctc
     2221 actctggtct tgctccattt ttttatcctc tatgaaggag gtcaactctt ttatcagctg
     2281 ttccttagcc ttactagcat ctgaaaacag ttggtcaagt gtaaaaggtt gcccatcttc
     2341 tgttaagtga acctttccta gactggtctt ttcagtctct tcaatcttaa aagcaactaa
     2401 atcatagatt tgtttggtca cattacgatt aacgactccc tttaaacctg actcttcttg
     2461 ctctgtatag tagaaaacaa gattgtcctt actttctagc ttgtccttaa catcttgatt
     2521 tatcagctcc ctaacagagg aaatcacttt ctccccttgg agaggataat aggcaatcac
     2581 ttcggcttgc ccctgacgaa aatgctcctt ctgatttccc tcactcaatt gatcatcttt
     2641 ctcttttttg agcgattcaa tcttttgctc aaaacttttt tgctggtaga tcttaaaagc
     2701 aataaatccg cctaataggc aaatagaaat tgctaaaata ccaatcaaag ccaataatac
     2761 atgtctcgtt ttcccgtgtc tgccacgtcc tagtctactt ttattcatat ttatatcata
     2821 acaaatttga gcaataattt caatgataca atttggcaat ccacaattcc tctagcaagc
     2881 caaagcatct tacatcaact ccaacatccg tatctgtaga gattatgtag ttttctatct
     2941 atggaatttc tagtagattg aagctagaat agtagaccta tacttctaaa acattgttag
     3001 aaatcgattt gactgtcctg atcgatttgt cctgttctca tttcatttta ctataaaact
     3061 atgaaaagct aggtcatctg agaagtaatt actatcgaca attgcgatag cgtatactag
     3121 tgcgatttgt ttgtagctct ggtgggtatc accttcacgt tggcgaattt tttctaggtt
     3181 ttgattaacc taactgcaca gataagccca taggcgattg atgaaaaaat tctgatgatg
     3241 aacctgaatt tcgatgataa cttggattcc attatctaac tccgccaaga cgtctatact
     3301 agtatagaaa tcctgcgctg agtagggcat ggaaggcaag acgtgaatgt tacttccctc
     3361 caaaatcgtc acattttttg ctggcaagtc cagcatatcg cggataaatt gacaaatcat
     3421 tagttgggct gatacccgga tgtctgagaa tcctcctttt cctccttcta ttatagcaca
     3481 tttttaaatc taggtttgct agattctatg cttctatcta tttattcgga aaagaaagct
     3541 tttcttcaga agaaagctaa tagcttattt gaaattttct cctctctgtt ggatagtccc
     3601 gtctatctat gttataatga aagaaggatt taaaatcgga aaaggagtat ttatgctaaa
     3661 attaggtgtc atcggaactg gcgctatcag ccatcatttc atagaagcag cccataccag
     3721 tggagaatac caactggtcg caatctattc tagaaaacta gaaactgcag caacctttgc
     3781 ttctcgctat cagaatatcc aactattcga tcaattagaa gtcttcttca aatcttcttt
     3841 tgatttagtc tatatcgcca gtccaaactc cttacatttt gctcaggcaa aagctgcctt
     3901 gtctgctggt aaacatgtta ttctcgaaaa gccagctgtc actcaaccac aagaatggtt
     3961 tgatttgatt caaacagctg aaaaaaataa ctgttttatc tttgaagcag ctcgtaatta
     4021 ccacgagaaa gcctttacta ctatcaaaaa ctttttagca gataagcaag tgttaggagc
     4081 agatttcaac tatgccaaat actcttccaa gatgcctgac ttgttgactg gacaaacacc
     4141 aaatgtcttt tcagaccgtt ttgctggtgg agccctcatg gatttgggga tttatcccct
     4201 ctatgctgct gttcgtcttt ttagaaaagc caatgacgcg acttaccatg ctcaacagct
     4261 tgacaatagc attgacctaa atggagatgg tatcctcttc tacccagact atcaagttca
     4321 catcaaggct ggaaaaaaca tcacttccaa tcttccttgc gagatttata caacagatgg
     4381 aaccttgact ctcaacacga ttgagcatat tcgctcagct atttttaccg accaccaagg
     4441 aaatcaagtc cagcttccta tccaacaggc tcctcatacg atgactgagg aagtcgctgc
     4501 atttgcacac atgatccagc aaccagatct gaatctctac caaacttggc tgtatgatgc
     4561 aggatctgtt catgagctac tatataccat gcgccagact gctggcatta gatttgaggc
     4621 agaaaaatga aaaccaaact accgactgaa tggcaagaac tgagtgacca actcggtttc
     4681 caagaattca cccccattca aactcaacta tttgagcccc ttcttgctgg agaaaacctc
     4741 ctaggagtga gccaaaccgg aactggtaag accctagcgt atctcctacc aagtcttctc
     4801 agactacaaa agaaaaaagc ccaacaactc ttgattctag caccaaatac ggaacttgct
     4861 ggacagattt ttgatgtatg taaaacgtgg gcagaagcta tcggattgac tgctcaactc
     4921 ttcctttcag gttcaagtca gaaacgacaa attgaacgcc ttaaaaaggg gccagaaatt
     4981 ctgattggaa ctcctggccg tatctttgaa ctcattaaac ttaaaaaaat caagatgatg
     5041 aatgtggaaa ccatcatcct ggatgaattt gaccaattac tagatgattc tcagattcac
     5101 tttgtagaaa aaatcactca ctacgcacct cgtgaccacc aactggtcta catgagtgcc
     5161 acgaccaagt ttgaccaaga aaagattgtg ccgaatacac gcactattga tctctctgac
     5221 caaaaattgg acaatatcca gcatttctac atgcaggtag accaacgtca tcgagtggat
     5281 atgctacgaa aactggctca tgtagaggat ttccgtggtc tagtcttctt caatagcctg
     5341 tcagaccttg ggaatgccga ggaaaaacta cagtatcgtg atatattgac tgtttccctc
     5401 gctagtgatg ttaatgttaa atttagaaaa atcatcttag aaaagtttaa agataaccaa
     5461 ctaaccctgc ttcttgcaac tgaccttttg gctcgtggaa ttgatatcga tagcctagaa
     5521 tgtgtcgtaa actttgatat tcctagagat agcgaaacct acacacaccg tgctggccgt
     5581 actggtcgta tgggcaagga aggatatgtt atcactctcg tcactcattc agaagaaatc
     5641 aaaaaactta aaaagtttgc aagtatccga gaaattgtcc taaaaaacca agaactctat
     5701 atcaaataaa gccccattgc tctatacaca tccagtgtat ggagcttttt tataagcaat
     5761 tcaattttat actcatctgc tttcaaaaag cattctagtc catctccgat taacgatggg
     5821 ctttatcacc tccttctcca gtccttgtat gatatcttga agttgattca tgacatcttc
     5881 caaagtttga aaggctttat tcttaaatcc acgtttacga atctctttca acacttgttc
     5941 aatggggttc atctctggtg tgtatggagg aataaaggta aaaccaatat tagtcggaat
     6001 ctttaaggta cttgatttat gccatatagc attgtccata acgaataaaa gataatcatc
     6061 tggataagct tgtgaaagct cttctaaaaa gacgttcatc cactcagtat tacatccacc
     6121 agctattaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac aatagcgaaa
     6181 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc aacaagatcc
     6241 cagtttactg attctaccga aaccagcctc atcttgggac atcaagtgaa ccttacgaaa
     6301 acgtctactg gttttaaatc gctttctttt cttcttgaat tgagatttta tttttagacg
     6361 cgacaatggt ttgagcgtct gctttcttag gatgttctgg acgtggcgta atatttcgcc
     6421 aaccatggcg cttcaacaat tgatagaagg catcacgtgt gtaggaacga cctaactcct
     6481 ttttataagc ctgaaataag gcatcaattg taacaaattc tcctgcctct gcagccttca
     6541 aatggcgggc aagaaagact ttcttttcct caactgtcat atatgcatgg ttacgaccac
     6601 cacgtgtttc ttgaaggaga gagtcgagtc cgaactcctc atattttttt acattttgct
     6661 aaatcgttgt ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca
     6721 gacgaaatag aacgatttga aggcgtttat gatatttagc tgtacgagag tgttttgatg
     6781 gtttggattt cttctttagt tgatttcata tcactattgt ataatgcttt ttgattttag
     6841 tctagtatta tactcttcga aaatctcttc aaaccgcgtc agcttcgcct tgtcgtatag
     6901 atgttactga cttcgtcagt tctatctaca acctaaaaac agtgttttga gcagtctgta
     6961 gctaactttc tatagtaaaa tgaaataaga acaagacaaa tcgatcagga cagtcaaatc
     7021 gattt
//
LOCUS       DAVLTG010000076         6663 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLTG010000076 DAVLTG010000000
VERSION     DAVLTG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.077"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            1..432
                     /locus_tag="VYN12_001900"
                     /pseudo
     CDS             1..432
                     /locus_tag="VYN12_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            599..799
                     /locus_tag="VYN12_001901"
     CDS             599..799
                     /locus_tag="VYN12_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416212.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            824..1241
                     /locus_tag="VYN12_001902"
                     /pseudo
     CDS             824..1241
                     /locus_tag="VYN12_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1472..2179
                     /gene="ccdA2"
                     /locus_tag="VYN12_001903"
     CDS             1472..2179
                     /gene="ccdA2"
                     /locus_tag="VYN12_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1416213.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLSVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2190..2747
                     /gene="sdbB"
                     /locus_tag="VYN12_001904"
     CDS             2190..2747
                     /gene="sdbB"
                     /locus_tag="VYN12_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1416214.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3121..4512
                     /locus_tag="VYN12_001905"
     CDS             3121..4512
                     /locus_tag="VYN12_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1416215.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4655..5572
                     /gene="adcAII"
                     /locus_tag="VYN12_001906"
     CDS             4655..5572
                     /gene="adcAII"
                     /locus_tag="VYN12_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1416216.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5580..>6663
                     /gene="phtD"
                     /locus_tag="VYN12_001907"
     CDS             5580..>6663
                     /gene="phtD"
                     /locus_tag="VYN12_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1416217.1"
                     /translation="MKINKKYLAGSVAVLSLSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTP"
BASE COUNT         2048 a         1227 c         1387 g         2001 t
ORIGIN      
        1 ataatccaga cgcttatttg actgaaatag cttctgaatt tggctgtcat ccaactacca
       61 tccactatgc gctcaaagct atgggctaca ctcgaaaaaa agaaccacac ctactatgaa
      121 caaaacccag aaaaagtagc cttatttctt aagaatttta atagtttaaa gcacctagca
      181 cctgtttaga ttgatgaaac aggatttgat acttattttt atcgagaata tggtcgctca
      241 ttaaaaggtc agttaagaag aggcaaagta tctggaagaa gatatcagag gatttctttg
      301 gttgcaggtc taacaaatgg tgaattaatc gctccaatga cttacgaaga gacgatgacg
      361 agcgactttt ttgaagtatg gtttcagaaa tttctcttac caacattaac cacaccatcg
      421 gttattatag taaaatggaa taagaacagg acaaatcgat caggacaatc aaatcaattt
      481 ctagcaatgt tttagaagtc catatgtact attctagttt caatatacca taactgctcc
      541 tagtcaacct gcaagtcctg tcccagctcc aagctcagct ccgactcaag atcctagagt
      601 ggtagtaagc gcttcggcta gctcaacgag cacacaagct caagagcaag ttgacaagtc
      661 tgaacttcgt gccttgagtc aagagttaga ccaacgcttg aaagctttgg caacagtatc
      721 tgatccgaaa atcgatgcaa ccaaggctgt cctcctagat gctcaaaaag ctccggaaga
      781 tagtgccttg acagagtaag gtctgcatac tgcagtagag tctgtgaaga ctgccttgga
      841 ctctctcaaa gatgtgatag caaatgctag cgacagcaag cctacacagg acaagaagga
      901 tgcaaaacaa ggaacggaag atagtaagga ttcagataag atgactgaaa caaactcagt
      961 tccagcagga gtgattgtgg tcagtctact tgccctccta ggcgtgattg ccttctggct
     1021 aattcgccgt aagaaagagt cagaaatcca gcaattaagc acggaattga ccaaggttct
     1081 aggacagcta gatgcagaaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc
     1141 tccaagaaac ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac
     1201 tagtagagga gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt
     1261 cagacctaaa agacattttc gttcacaaaa gcagcgacga gtaatccttg tcgttgcttt
     1321 ttggctattt ttggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag
     1381 tgcccgatac gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag
     1441 gattagaatt attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt
     1501 ttttctagca ggtgttttat cctttttttc tccttgtatt tttcctcttc tgtcagtcta
     1561 tgctgggatt ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa
     1621 ggttctctgg tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt
     1681 ctttattcta ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg
     1741 atatggcatg ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt
     1801 gaagaaatta gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg
     1861 gtcagctttt ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt
     1921 tttaagttct gttttagcac ttgcggcttc tggaggcaat ggcgcttggc aaggagcgat
     1981 ttatactctc atttacactc tgggcatggc ccttcctttc ttggtattgg cactagcttc
     2041 aggtctagtc atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat
     2101 tggtggtttc ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct
     2161 agctggaatt tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc
     2221 tcttgtcatt agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag
     2281 cacaacagcc aaaacaacaa acgactgtac aacaaattgc tgttggaaaa gatgctccaa
     2341 acttcacatt gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa
     2401 aggtttactt gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt
     2461 tgatggaact agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag
     2521 gaattcaagg tgaaaaaatt gttgagcaat tcccacaatg gttccaggaa caaggatata
     2581 aggatatccc agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa
     2641 gcattcctac agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg
     2701 ctatcagtaa tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc
     2761 tgattacaag atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa
     2821 cctagctttt agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt
     2881 ccactggttt tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaagt
     2941 gcacgacaaa tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag
     3001 atggaagtta ctttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat
     3061 attcacatat ctcctatatt tatggtaaaa tagaatcatc agtttatttt ggagtcaaag
     3121 atgaatatat ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg
     3181 aagttatggg atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca
     3241 atcacaggta ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt
     3301 tctgccttgt gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc
     3361 gctacaggag gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg
     3421 gctggttggt taaccatgat ggagttcatg acagccatat caggcgtagc ttcgggttgg
     3481 gcagcttatt ttaaaggctt gctctctcaa tacgggatag cctttcctca ggctttaaat
     3541 ggtaccttta atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc
     3601 ttggtgactt cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta
     3661 gttattttga aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag
     3721 tttgataatt ggagcaattt tgctccttac ggttttggac aaatctatgg agctagcact
     3781 ggtattatgg ctggtgcgtc cttgatgttc ttcggttttt tgggatttga atccatctct
     3841 atggctgtag atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg
     3901 ctttctatcg taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac
     3961 tatagtcatt taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt
     4021 tgggcagcca actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg
     4081 atgacctatg ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct
     4141 gcctttaagg aactgacgaa gactagcaag ataccaaaga atgctactat cttgacaggt
     4201 ctagcttcag cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat
     4261 atttgtacct tagcctactt gatcatgttg gcttatggtc tgattcgctt acggaaagaa
     4321 aaaggaatgc ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta
     4381 tcgatcatca tttgtttatc cttcatgtta cagtataata tgaatacctg gattgctttc
     4441 ctagttgcgt tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc
     4501 atagaagaat aaagtgaaag tctattgagt tgttgacact cagcagattt ttatatgtga
     4561 aagaaatttc aaattttttc taaaaatatc ttgacagatt aaattttcag gagtagaata
     4621 tttactagtt aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt tatttttagt
     4681 cctgttaagt gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg
     4741 aaaggggatg aaaattgtga ccagttttta tcctatctac gctatggtta aggaagtatc
     4801 tggtgacttg aatgatgttc ggatgattca gtcaagtagt ggtattcact cctttgaacc
     4861 ttcggcaaat gatatcgcag ccatctatga tgcagatgtc tttgtttacc attctcatac
     4921 actcgaatct tgggcaggaa gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt
     4981 agaggcttct gagggaatga ccttggaacg tgtccctgga ctagaggatg tggaagcagg
     5041 ggatggagtt gatgaaaaaa cgctctatga ccctcacaca tggctagatc ctgaaaaagc
     5101 tggcgaagaa gctcagatta tcgctgataa actttcagag gtggatagtg agcataaaga
     5161 gacttatcaa aaaaatgcgc aagcctttat caaaaaagct caggaattga ctaagaaatt
     5221 ccaaccaaaa tttgaaaaag cgactcagaa aacatttgta acacaacata cagccttttc
     5281 ttatctagcg aagagatttg ggcttaatca acttggtatt gcaggtatct ctcctgaaca
     5341 agaaccaagt ccacgacaac taacagaaat tcaggaattt gttaagacct ataaggttaa
     5401 aacgattttt acagaaagta acgcttcttc aaaagtagct gaaactcttg tcaaatcaac
     5461 aggtgtgggt cttaaaactc tgaatccttt agagtcagac ccacaaaatg acaagaccta
     5521 tttagaaaat cttgaagaaa atatgagtat tctagcagaa gaattaaagt gaggaaagaa
     5581 tgaaaatcaa taaaaaatat ctagcaggtt cagtggcagt cctttcccta agtgtttgtt
     5641 cctatgaact tggtcgtcac caagctggtc aggttaagaa agagtctaat cgagtttctt
     5701 atatagatgg tgatcaggct ggtcaaaagg cagaaaattt gacaccagat gaagtcagta
     5761 agagagaggg gatcaacgcc gaacaaattg ttatcaagat tacggatcaa ggttatgtga
     5821 cctctcatgg agaccattat cattactata atggcaaggt tccttatgat gccatcatca
     5881 gtgaagaact tctcatgaaa gatccgaatt atcagttgaa ggattcagac attgtcaatg
     5941 aaatcaaggg tggctatgtg attaaggtag acggaaaata ctatgtttac cttaaagatg
     6001 cggcccatgc ggacaatatt cggacaaaag aagagattaa acgtcagaag caggaacgca
     6061 gtcataatca caactcaaga gcagataatg ctgttgctgc agccagagcc caaggacgtt
     6121 atacaacgga tgatgggtat atcttcaatg cttctgatat cattgaagat actggtgatg
     6181 cttatatcgt tcctcacggc gaccattacc attacattcc taagagtgat ttgtctgcca
     6241 gtgaattagc tgctgcccaa gcctattgga atgggaagca gggatctcgt ccttcttcaa
     6301 gttctagtca taatgcaaat ccagctcaac caagattgtc agagaaccac aatctgactg
     6361 tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta cgtgaattgt
     6421 atgctaaacc cttatcagaa cgccatgtgg aatctgatgg ccttattttc gacccagcgc
     6481 aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat taccacttta
     6541 tcccttatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt ccccttcgtt
     6601 atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca caatcgactc
     6661 cgg
//
LOCUS       DAVLTG010000077         6455 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLTG010000077 DAVLTG010000000
VERSION     DAVLTG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.078"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            119..1069
                     /locus_tag="VYN12_001908"
     CDS             119..1069
                     /locus_tag="VYN12_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1416218.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1246..2253
                     /gene="gap"
                     /locus_tag="VYN12_001909"
     CDS             1246..2253
                     /gene="gap"
                     /locus_tag="VYN12_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1416219.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2321..3157)
                     /locus_tag="VYN12_001910"
     CDS             complement(2321..3157)
                     /locus_tag="VYN12_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1416220.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3283..5478
                     /locus_tag="VYN12_001911"
     CDS             3283..5478
                     /locus_tag="VYN12_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1416221.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5531..5683
                     /gene="rpmG"
                     /locus_tag="VYN12_001912"
     CDS             5531..5683
                     /gene="rpmG"
                     /locus_tag="VYN12_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1416222.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5693..5869
                     /gene="secE"
                     /locus_tag="VYN12_001913"
     CDS             5693..5869
                     /gene="secE"
                     /locus_tag="VYN12_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1416223.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5924..>6455
                     /gene="nusG"
                     /locus_tag="VYN12_001914"
     CDS             5924..>6455
                     /gene="nusG"
                     /locus_tag="VYN12_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1416224.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2004 a         1123 c         1405 g         1923 t
ORIGIN      
        1 gaggctcttt tgtcttgttc ttgtttcaat tgactatagt tcacggatac agttgggaaa
       61 gaagctatta aatatttgga gagtcctttt gggatgaaca tgtcaaatat tactatagat
      121 gggcaagaaa agatgggcaa gaaatggatc tgagtcaaac gatgcttctt atgctcaagt
      181 agtgagtctt tatgatgata caagtatctc tgttagtaat aatgagacgg acaaagtgtt
      241 gactggatcc ctctatactg aaacaaatga acagggatta acgattccaa gcagtttact
      301 aaaaaattgg aatgaacaga caggaaaaaa tttgacaact aatgatctta ttggcaaatc
      361 agtctcagcc agcattgtag aaagtgctgc cgaaactagt aagattgctc aatttcaaac
      421 gaagattgta cgtgtaatca atgatgaaga tgacatggag gacagcaaca gtttcatgct
      481 gtctcatcaa atggaaacga ttttgaaaga ggctggattt acgaaagctg tatcttattt
      541 tatcttggaa ctcaaagatc catcacagac aaaagtagta acagaagaat tacagaaaaa
      601 taagaagtat actgtgcttt ctcaacagag agttcttgat attgtgatta cctttattcg
      661 tgttattcag ggattattga ttgtgctttc atcacaagct attgtggtag cggcggttat
      721 gattggtatc attatttaca tcaatatcat gcaacgttcc aaggaaatag gtgtcatgaa
      781 agcagttggt tatcagaatc gtggtgtcaa aggaattttt atttacgagg ctatctggat
      841 tgtaggcatc gccttgctgc tggcattttt ggttgcacaa ggggtgggaa gtttggcgaa
      901 tgcgattgta agtcactttt acccatccat cactaaggtt tttgaattaa atcttttatc
      961 tgttttagga actctagttt tcgctctatt acttggttat gtctcagcct acttcccggc
     1021 gcgtaagatt agtaaaatgg atcctgtaga atcgttacgc tatgaataat aagggattcc
     1081 ttgatttaca gtcttaaaaa gaaactcaca tagaaaaaca atggccatac ttgcaattca
     1141 actcaaatag ttgtataata ggtttgttga aaggtgattt gtagtgattc aagttactct
     1201 tttcacaata aaaatttcat gattttcata aggaggaaat cactaatggt agttaaagtt
     1261 ggtattaacg gtttcggacg tatcggtcgt cttgctttcc gtcgtatcca aaacgtagaa
     1321 ggtgttgaag ttacacgcat caacgacctt acagatccag ttatgcttgc acacttgttg
     1381 aaatacgaca caactcaagg tcgtttcgac ggtactgttg aagttaaaga aggtggattc
     1441 gaagttaacg gtaaattcgt taaagtttct gctgaacgtg atccagagca aatcgactgg
     1501 gctactgacg gtgtagaaat cgttcttgaa gctactggtt tctttgctaa gaaagaagca
     1561 gctgaaaaac accttaaagg tggagctaaa aaagttgtta tcactgctcc tggtggaaac
     1621 gacgttaaaa cagttgtatt caacactaac cacgacgttc ttgacggtac tgaaacagtt
     1681 atctcaggtg cttcatgtac tacaaactgc ttggctccaa tggctaaagc tcttcaagat
     1741 aactttggtg ttgttgaagg attgatgact actatccacg cttacactgg tgaccaaatg
     1801 atccttgacg gaccacaccg tggtggtgac cttcgccgtg ctcgcgctgg tgctgcaaac
     1861 atcgttccta actcaactgg tgctgcaaaa gctatcggtc ttgtaatccc agaattgaat
     1921 ggtaaacttg atggatctgc acaacgcgtt ccaactccaa ctggatcagt tactgaattg
     1981 gtagcagttc ttgaaaagaa cgttactgtt gatgaagtga acgcagctat gaaagcagct
     2041 tcaaacgaat catacggtta cacagaagat ccaatcgtat cttcagatat cgtaggtatg
     2101 tcttacggtt cattgtttga cgcaactcaa actaaagttc ttgacgttga cggtaaacaa
     2161 ttggttaaag ttgtatcatg gtacgacaac gaaatgtcat acactgcaca acttgttcgt
     2221 actcttgaat acttcgcaaa gattgctaaa taattcttga gttgatagaa agcaaggctt
     2281 tgtggtcttg cttttttata tggaaaaatg gatgacacga tcatccattc ttttttaatt
     2341 ctttttcaaa tgtatttgaa agggtagtga aagttagcct ctctaaagta agtgggtggg
     2401 taaaggaaag tcggaaggca tgaagcataa gccggcttgt ctttgattta ctattataga
     2461 gagggtctcc caggatagga agattatgat gcaaaaggtg cacacgaatc tgatgggttc
     2521 gccctgtctt tagcttgcaa tgagccaagg aagtcttgtt tgagaattgc tttaatctgc
     2581 ttacatgcgt ttcagcatat ttcccatttt ttgcatcaac tattcttttt ctacgatcat
     2641 ggcgatcacg tccaattttg tctctgaaaa caagttcttt tctgttgata tttccatcaa
     2701 ctagagccca atattctcta gaaatctctt ttttctccaa taagcgattg agaatgggca
     2761 ggataaaagg atttttggca aagagaacta agccactggt ttccatgtcc agacgatgaa
     2821 cgacatagca ggtttggcca acataggtac tgacatggtt aagaagggca atttcgtttg
     2881 gttgattacc atgcgttttc atcccctctg gtttgtttac aataatcaag tgttgatctt
     2941 gataaacttc ctgcactaag tctgggttgc cccaagggat cgtcttttgg ggataatctt
     3001 cctcgtcaaa agtcaactgg caaacatctc caggatttac gatttcgttc cagcggactt
     3061 cttcttgatt tatcaaaata tgtttcttga ttctcaaaaa atgacggatt tttctaggga
     3121 tgaggagttg ttcctcaagt aattgcttta ccgtcatttg aggtagagag gcgggtaatg
     3181 taaatgtgaa ttgcatacag atattgtaac aaaaaaagcc ctatttggat aggaaatagc
     3241 taaattcttg tcttcctatg atgaagatga taaaataaac gcatgaaatt agataaatta
     3301 tttgagaaat ttctttctct ttttaaaaaa gaaacaagtg aactagagga ctctgattct
     3361 actatcttac gtcgctctcg tagtgatcga aaaaaattag cccaagtagg tccgattcga
     3421 aaattctggc gtcgttatca tctaacaaag attatcctta tactaggttt gagtgcaggc
     3481 ttgctagttg gaatctattt gtttgctgta gccaagtcga ccaatgtcaa tgatttgcaa
     3541 aatgccttga aaactcggac tcttattttt gaccgtgaag aaaaagaggc tggtgccttg
     3601 tctggtcaaa agggaaccta tgttgagctg actgacatca gtaaaaactt gcagaatgct
     3661 gttattgcga cagaagaccg ttctttctat aaaaatgacg ggattaacta tggccgtttc
     3721 ttcttggcta ttgtcactgc tggacgttca ggtggtggct ctaccattac ccaacagctg
     3781 gctaaaaacg cctatttatc gcaggatcaa actgttgaga gaaaagcgaa agaatttttc
     3841 cttgccttag aattaagcaa aaaatatagt aaggagcaaa ttctaaccat gtaccttaac
     3901 aacgcttatt ttggaaatgg tgtgtggggt gtagaagatg cgagtaagaa atactttgga
     3961 gtttctgcat cagaagtgag tctggatcaa gctgcgactc tggcagggat gctcaagggg
     4021 ccggaactgt ataatccctt gaattccgta gaagattcta ctaatcggcg cgatactgtc
     4081 ttgcagaata tggttgcagc aggatatatt gataaaaacc aagaaaccga agctgctgaa
     4141 gttgatatga cttcgcaatt gcacgataag tatgaaggaa aaatctcaga ttaccgttac
     4201 ccctcttatt ttgatgcggt ggttaatgaa gctgtttcca agtataatct aacagaggaa
     4261 gagattgtca ataatggcta ccgcatttac acagagctgg accaaaacta ccaagcaaat
     4321 atgcagattg tttatgaaaa cacatcgcta tttccgaggg cagaggatgg aacgtttgct
     4381 caatcaggaa gtgtagctct cgaaccgaaa acagggggag ttcgtggagt tgtcggtcaa
     4441 gttgctgaca atgataaaac tggattccgg aatttcaact atgcaaccca atcaaagcgt
     4501 agtcctggtt ctacaattaa gcctttagtt gtttatacac cagcagttga agcaggctgg
     4561 gctttgaata agcagttgga taaccatacc atgcagtatg atagctataa ggttgataac
     4621 tatgcaggga tcaaaacaag tcgagaagtt cctatgtatc aatccttggc agaatcgctt
     4681 aatctacctg ctgttgccac tgttaatgat ttgggtgttg acaaggcttt tgaggcaggc
     4741 gaaaaattcg gactcaacat ggaaaaggtc gaccgtgttc ttggtgtcgc cttgggaagc
     4801 ggtgttgaaa ccaaccctct tcaaatggct caagcatacg ctgcctttgc aaatgaaggt
     4861 ttaatgcctg aagctcattt tattagtaga attgaaaatg ctagtggaca agttattgcg
     4921 agtcataaaa attcacaaaa acgggtgatt gataagtctg tagctgacaa gatgaccagt
     4981 atgatgttgg ggactttcac caacggtacc ggtattagtt catcgcctgc agactatgtc
     5041 atggcaggga aaactggaac aactgaagca gttttcaatc cggagtacac aagtgaccag
     5101 tgggtaattg gttatactcc ggatgtagtg attagccact ggcttggctt tccgaccact
     5161 gatgaaaatc actatctagc tggctctact tcaaacggtg cagctcatgt ctttagaaac
     5221 attgccaata ccattttacc ttatacgcca ggaagtacct ttacggttga aaatgcttat
     5281 aagcaaaatg gaattgcacc agccaataca aaaagacaag tacaaaccaa tgataatagc
     5341 cagacagatg ataatttgtc tgatattcga gggcgtgcgc aaagtctagt agatgaggct
     5401 agccgggcta tctcagatgc gaagattaag gaaaaggctc aaacaatatg ggattcgata
     5461 gtcaatctat ttcgctaaga tgcttgtcaa agcctagctt tcttgttata atggataaga
     5521 tggaggcgtt atggcactaa aaaaagcaag cctagcttgt gcggtttgtg gttcgagaaa
     5581 ctattcaatc aagatcagcg gaaaccccaa gcctacacga ctagaagtaa ataaattttg
     5641 taagcattgt ggcaagtaca ctacacacag agaaacgaga taggagagag cgatgcgttt
     5701 tattggagat atttttagac ttcttaaaga cacaacatgg ccaactcgca aggaaagctg
     5761 gagagatttt cgttctatca tggaatacac agctttcttt gtagtaatta tttacatttt
     5821 tgaccagttg attgtttcag gtttgattcg atttattaac attttttaga agattagtgg
     5881 agttaattac actagaaatc ttctatttat gaaaggaaat atcatggata gttttgataa
     5941 aggatggttt gttttacaaa cttattctgg ttatgaaaat aaggtgaaag aaaatctatt
     6001 acaacgtgca caaacctaca atatgttgga taatattcta cgcgttgaaa ttccaacaca
     6061 aacagtgcaa gttgaaaaaa atggaaagag aaaagaagta gaagaaaatc gctttccagg
     6121 ttatgttctt gtagaaatgg tcatgacaga tgaagcttgg tttgttgttc gaaacacacc
     6181 aaatgttaca ggatttgtcg gatcacacgg gaacagatca aaaccaactc cattattgga
     6241 acaagaaatt cgtgacattt tggtatctat gggacaaact gttcaagaat ttgatttcga
     6301 tgttgagatt ggtcaaactg tacgtattat tgatggtgct tttgcagact acactggtaa
     6361 gattacagaa attgataata acaaagtgaa aatgattatc tctatgtttg gtaatgacac
     6421 agttgcagaa gtaaacctaa accaaatcgc agaat
//
LOCUS       DAVLTG010000078         6045 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLTG010000078 DAVLTG010000000
VERSION     DAVLTG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.079"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..701)
                     /locus_tag="VYN12_001915"
     CDS             complement(<1..701)
                     /locus_tag="VYN12_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1416225.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYF"
     gene            complement(703..1260)
                     /locus_tag="VYN12_001916"
     CDS             complement(703..1260)
                     /locus_tag="VYN12_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1416226.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKVTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(1247..1696)
                     /locus_tag="VYN12_001917"
     CDS             complement(1247..1696)
                     /locus_tag="VYN12_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV1416227.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(2108..2503)
                     /locus_tag="VYN12_001918"
     CDS             complement(2108..2503)
                     /locus_tag="VYN12_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1416228.1"
                     /translation="MSKKLNRKKQLRNGLRRSGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(2599..2853)
                     /locus_tag="VYN12_001919"
     CDS             complement(2599..2853)
                     /locus_tag="VYN12_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1416229.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(2863..4197)
                     /locus_tag="VYN12_001920"
     CDS             complement(2863..4197)
                     /locus_tag="VYN12_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1416230.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTIAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(4197..4430)
                     /locus_tag="VYN12_001921"
     CDS             complement(4197..4430)
                     /locus_tag="VYN12_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1416231.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            4461..4538
                     /locus_tag="VYN12_001922"
                     /pseudo
     CDS             4461..4538
                     /locus_tag="VYN12_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4833..5021)
                     /locus_tag="VYN12_001923"
     CDS             complement(4833..5021)
                     /locus_tag="VYN12_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416232.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(4981..5163)
                     /locus_tag="VYN12_001924"
     CDS             complement(4981..5163)
                     /locus_tag="VYN12_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416233.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(5165..5944)
                     /locus_tag="VYN12_001925"
     CDS             complement(5165..5944)
                     /locus_tag="VYN12_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416234.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         1781 a         1363 c         1050 g         1851 t
ORIGIN      
        1 ttaaagtatt ctttcactag agctatagcg tcaatcttag atgtttcttg gtttagtttt
       61 atcaactccc ctttcaattt tttccattta aagttggaat ttaaaagata atctaaatca
      121 atatagaaat ctattataac agtctcatca tctgggctaa cagcttttac ctcatttatt
      181 ggtaagtcag tatgttgcga ataatttctc aaagaatggc aaaatcgata agtaaaattg
      241 atatcatact gatagcttgc aaaaccatgt atacaatcaa actcctcact atctttggaa
      301 tatttttgtt taatttggtt ttcgttaaaa tcgacaaaca attttccact ggataataaa
      361 tgaatcatga aacgatttac atctgcctct tcaatttcta attcctttga ctcaagttta
      421 tttttaatac ttaaaaaatc cgagacatct gaaataaaca attcgaacat attcttgatt
      481 ttttgaaaat tcttttgaat ctcaaaaatt tggtccgaga ctgacattat ttccttggtt
      541 ggttcaatat cagagatgac aatacgtttt tcattgttgt taatttctaa ataagctaat
      601 cgctcgataa tatcactatc atttaattca gcatactcaa catcaatttg gcgtaactgc
      661 ttctcagata gagagcttac ttcctctttt acatcgctca tcttattcct cccactcgct
      721 cttcagcaag ccatatatca gactgtcaca gcggtttcct tgaacatcct ttcggtctct
      781 tatgcgagct tcgagggtaa agccaagctt ttccgcgact cgtttacttt gaaggttata
      841 tccaaagcaa gttagttcaa tcttgtgaag acccaaatct ttaaaggcta agtcaatcaa
      901 ggcacgcgca gcttctggca cataacctcg cccccaatag tctgggtgta aggtatagcc
      961 gatttccagc acatcatctt catggcgatg gttgaaatcg acagagccaa cgatcttatc
     1021 cgttactttg acgacaatcc cgtagcctgc tgggagattt tccttttgat tacgctccgg
     1081 aagaatgtgc tccagataat aaatctcatc ttccaaggtc ttgactggag gaaaacctgc
     1141 tggataggcg acctctggca aactagcata gtcaaagata tcctcagcat ccgccacagt
     1201 acggactcgt aaaacgagac gttctgtttc gattttatct ggcagctcag ttcttgccat
     1261 ccttcttcct cgcttttttg atgaaactgc ccttcatatc tacacgctta tccagatagc
     1321 gataaacgcg ctgatatcca tctcccatga aataggttgg ggcaaacagt tgatttttaa
     1381 aatgtccctt ttcatccagg agttctgggg caacaagtcg ctcaagaatc ttggcaaaga
     1441 tgtggcaaat accgtcttcc tcaacaatcc tatctacccg acaatctaaa acaagtggac
     1501 aggcgtctaa aataggaatc tgagttcgtt cagaaatttc ataatgcact cccaaacgtt
     1561 ccaatttctc ctgatgactg ataaaaccag cctgctccat cgcaagcata gaagtttcat
     1621 cagaaatatt cacagtaaat ttttgatact gtttgatctg ctctgcggca ttctctctcg
     1681 caacgactcc aatcacaacc caatctccta gactataaga ggaactacag gtcgtgatgt
     1741 tatagccaaa attctaatct tgatatccta aaataaaaac aggaaaacca taatatagtt
     1801 tattagtttt aaatgattgt tttataacaa cctcctttga ctaagacaca aaagaaaagc
     1861 cctgccatct acatgacagg gacgaatgtg tttatccgcg gtaccaccca atttcgggcc
     1921 aagcccgcat ctttagtctt taaaataaaa agacagaaat atttcatttt ttcagtcatt
     1981 agcaaccagt tttgacacat ttgtggactt ctcagcgccg ccactttctg taaaatgtgg
     2041 gattcaaaac acctctaatg gctctattgt agcaagtttt tctcggaaat gcaaggctca
     2101 agaaaaatta cttgaacttg atgccatttt ctttcaattt cttgatggta gctgggccga
     2161 ttcctttcaa ggcaaggagt tctttttcag tccagttttt gaaatctgaa gcagacttga
     2221 ttccttcatc atagaaagtc ttggcacgat caagtggaag tccacccaag tttgctgcaa
     2281 aatcttctac agaattagct actttttgag cttgctcttt ggtagcttct actgcttgtt
     2341 caactttttt agaaacagcc ttaccagctg cgcttgctga ctgttctgca cgcttcacga
     2401 ctttttttgt ctcatctaca accttagtca cagtacttga aaaggcacct gagcgacgga
     2461 ggccatttcg taattgtttt ttacgattga gtttctttga catgataaaa tcctttcaat
     2521 aaaaaatccc tgctctgaca aggatttaac ataaacattc tatcaagatt ttagtgaaaa
     2581 atcaagaatc tttctcgttt aataatttcg ctcaccaaac aagccttctg gcaaatcatg
     2641 gaatcccttg cctgctttga agttttcaaa cttaccaagc aagaactgat aagcatccaa
     2701 gcgactctcg tagcgaatca tggcatcttt ggcacgctcg tcctggtctt cttcgtaaac
     2761 tttttgactt tccttgtgcg ccatgtcgtt aatcatgatt tgggtattga cccaagcttc
     2821 aaattccttc ataaattctt gttcgtaact cattttttct ccttattcta atccacgaaa
     2881 atagtccgta tcaatctcac ggtagggctg gatatcctga acatactcca acactccttg
     2941 gaattctccg tcttcatcgt gtactgcagc ataggtgatg tggacaaact tacctcgcga
     3001 ctcagacttg aaccacattt catacttgtc cttggtcccc tcacgaagcc ccttcatgat
     3061 agttttgacc ttgtccaagt acttaggcgg atggcagagt tcgacattgc gcccgacttg
     3121 agacggcgtc cgtttgaaaa tcatctcatc agctggcgta ttgtcattgt aatactggaa
     3181 aatatcatct ttattgacaa aggtaatctc catagggagg tgattgagga tgagattggc
     3241 ctgctcgact gaaagatagc cattaccaaa agcctgttga ctatggcggt ccagcacagc
     3301 ttccttttcc ttaggggtaa aggtaatggt aaaatggcct tctggcgtat ctatgacttg
     3361 ttgaacttga ccttctgccg tatctagctg tacaggctcc tctgcaatct tttcctcaat
     3421 aaagctctgt cgttctggca cccatttctc tgacggacgg atgatggcat agccataggc
     3481 atcgctctcc tccgcaatct gaagccagtc atcctgagta aaagactcaa ggagaatcat
     3541 gaggaggatg gactcttcct tgaaaatcat actttcaaac tctgtcgcaa aagcttcaaa
     3601 agcttccttt acactgctaa ttgacacttc tggtagtgac ttggctatcg ttagagctgt
     3661 ttgaaagagt tccctaatct gatcatccac tccccacata actttgggag gtgaatcgtg
     3721 tccatagcgc tccatgatag gaaagaagag ttcttcctta cgttggtaat ggatgtcaaa
     3781 ttgacccaca agtcccatct gacgcaccaa acccttacgc atctccgcca gcatttcctc
     3841 gtcttccata gactcatagg tatctaacaa tctacgaatg cgaatcaagg ccgcacggag
     3901 agccagattt tcttctttga agacacgaac tgggtgacct ggatgctcag tatctgaaac
     3961 ttcgacacct ttgatagcat ttttaaaaag attggcatgg acatcacaga gttccataac
     4021 atcttcaaag gtgacacctg agtctgagtt catcagctcg tgctccataa gggaaatctc
     4081 aatggctgag acacccgcaa aggtcgcatc aaaacgctcc tgaaccgact caggagaggc
     4141 gccattatgc aattctaata aaatatcccg taggacatga atccgttcat ctgccattag
     4201 tctaatccaa tcacttcgta gccattcgct tccagtgtgc gtacaatctt gtccatagga
     4261 gttcctgcta gcttagaacc ttgtttaagt gatactttac gaccaactgt attgcgcatc
     4321 aagggattgg caaggggttt aaaacccagc tccactagaa tttccaagac ttctggatgc
     4381 ttgtccacca cttctgcaac aggaattgac acatcgatga tattgtccat gacgacctcc
     4441 attatatgtt ctaatactca atgaaaatca aagagcaaac tagaaagcta gccgcaggtt
     4501 gctcaaaaca gtgttttgag gttgtagata gaactgacga agtcagctca aaacaccgtt
     4561 ttgaggttgt ggatagaact gacgaagtca gctcaaaaca ccgttttgag gttgtggata
     4621 gaactgacga agtcagctca aaacaccgtt ttgaggttgt ggatagaact gacgaagtca
     4681 gtaacatata tactgcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
     4741 aatgatttta ctgcttatat tataccatat ggagagagat taaaaaacta gcagtggagt
     4801 tcctgctagc tctctgcgac ttggattacc atctagataa gtttaaagag ccaatccaat
     4861 atcttaaata atatcttgta aaacagcaat tgaactgcaa aggaaatgat catccaaaag
     4921 aatttcacaa tcccaataat cggtttgata aaaagaatag caagaagacc aaaaaaaatt
     4981 tcattctctc tcctctggcc taatgagcca ccgagccgta tccattagct tatctgcaat
     5041 aaaaagtttt cccagaccaa caacgacatg gtcagctttc tttatcgttt tcatcacttt
     5101 tacaccttgc acggtcaaaa agtaattacc ataaatttta tcaaaagctt tgataggatt
     5161 catattactc tcctttaatg atttcagcct cttttcggat tgtttcaaca tcttcttgat
     5221 attgaacttc actatagttg actagcttgg ataattcttt ctgcaagctt tcccccattg
     5281 gtttcatagt tgcaaaggtt aaaccacctg caatgatacc acccaagata ggaataaatt
     5341 tccctattcc tttggccagc cctcccttgg taagattcac accaaatatt tttaagactt
     5401 ttttcaaaat agggtaccaa agcgtctttg ttaaagcttt attaggcact gttttcatta
     5461 cctgtttggc aattgttata ccaccagcac atagcaaagc agcggttcca ttcaccccta
     5521 acattacgcc tagataaagc aagagggtat tttgagcatc ttcactcaac tcctcgcgtg
     5581 aagcccaaag atcctcataa ccataaatat aacctaattc ttgagccaat ttcagagaga
     5641 aagcataaaa ttgagccaca tcagctggaa tggtaattgc catagcaagc cctccagcta
     5701 atcctgccaa aacagaagtc ccactcgcta ataatacatt gtcccgaata caagcattag
     5761 ctacacgatc taatatttct tgagatagaa gagtcgttgt accttgttcc aataaggtag
     5821 gaatatcttt tggatccaat tctttggaaa acttatccac taaaaatttc gaacgatcaa
     5881 ccttaacaac aggtagtttc accacttgtt gcaatacttg catagctaag tcttgttcag
     5941 ccatatacaa actccttatt tcttttttac accttatcat attatatttc ctacaaaaaa
     6001 agcattttct aattagataa cattaaaaaa tacagaaccc ctttt
//
LOCUS       DAVLTG010000079         6010 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLTG010000079 DAVLTG010000000
VERSION     DAVLTG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.080"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            128..1897
                     /locus_tag="VYN12_001926"
     CDS             128..1897
                     /locus_tag="VYN12_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1416235.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHTDKSTEDSLEAAQAATKAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1921..3876
                     /locus_tag="VYN12_001927"
     CDS             1921..3876
                     /locus_tag="VYN12_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1416236.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKLEEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3878..4315
                     /locus_tag="VYN12_001928"
     CDS             3878..4315
                     /locus_tag="VYN12_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1416237.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4377..5513
                     /locus_tag="VYN12_001929"
     CDS             4377..5513
                     /locus_tag="VYN12_001929"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1416238.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1844 a         1006 c         1228 g         1932 t
ORIGIN      
        1 taatttttaa gcctttttgc ccagcctcgt caaaagtaat gttttgacac aaaatctgtg
       61 acaaaacttt agttttaaag gtttttaact ttgtatatac tagttttaag aaaaggagga
      121 tgatctaatg gaagaaaaag tatcattgaa agtcagggtt caaaaactag ggacatcgct
      181 ttcaaatatg gttatgccca atattggagc atttattgct tggggagtat tgactgccct
      241 ctttatcgct gatggctatc tgccaaatga acagttagct actgttgttg gtcctatgtt
      301 aacgtattta ttgccaatcc tgattggtta cacaggtgga tatatgatcc atggccaacg
      361 tggtgccgtt gtaggagcta ttgctactgt tggtgcaatt acaggttcta gtgttcctat
      421 gtttatcgga gctatggtaa tgggcccact gggaggatgg actatcaaga aatttgatga
      481 gaagttccaa gaaaaaattc gtcccggatt tgaaatgtta gttaataact tctcagctgg
      541 tctcgttggt tttgcattat tgcttttggc tttctacgca atcggtccag tcgtatcgac
      601 tcttactgga gctgttggga atggtgttga ggctattgtc aatgctcgcc tccttcctat
      661 ggctaatatt atcatcgaac cggctaaagt ccttttcctc aataatgccc tcaatcatgg
      721 catttttact cctctgggag tagaacaggt agctcaagct ggtaagtcaa ttctcttcct
      781 attggaagct aatcctggac caggcctggg aattctatta gcttatgctg tattcggtaa
      841 aggttctgct aaatcttctt cttggggggc aatggttatt catttcttcg gagggattca
      901 tgaaatttac tttccttatg ttatgatgaa gcctactcta tttttagctg ctatggcggg
      961 aggtatctct ggaactttta cttttcaact cttagacgct ggtcttaaat ctccagcttc
     1021 accaggttct attattgcga ttatggctac ggcgccaaaa ggtgtttggc cccatataaa
     1081 tgttcttcta ggtgttttag tagcagcagt tgtttctttc cttgtagcag cccttattct
     1141 tcatacagac aagtcaactg aggattcgct cgaagctgct caggcggcta ccaaagcagc
     1201 taaggctcag tctaaaggtc agttagtatc aacttctgtt gatgcagttg tttcgacaga
     1261 ctcagtggaa aaaatcattt tcgcctgcga tgctggtatg ggaagctctg ctatgggagc
     1321 tagtattctt cgagataagg ttaaaaaagc aggtctagag attccagtat ctaatcaggc
     1381 aatctcaaat ttgcttgata caccaaaaac attaattgtt actcaggaag aactgacacc
     1441 aagagctaaa gacaagagtc caagtgctat tcatgtttct gttgataatt tcttagcgtc
     1501 ccctcgttat gatgaaattg tagcttcatt aacaggagct tctccaatag cagaaattga
     1561 aggagatata ccaacttcag caccagtaga tagtcaggaa attgacctta accatattga
     1621 tgctgtagta gttgcttatg gtaaagcaca gggaactgca actatgggct gtgaaacgat
     1681 tcgggctatc tttagaaaca agaatattcg tattccagtt tctactgcca aaatttcaga
     1741 attaggtgaa tttaattcta aaaacataat gattgtaaca actatttctt tacaggcaga
     1801 agtgcagcaa gcagcaccga attctcaatt tcttattgtg gatagtttag taacaacacc
     1861 agaatatgac aaaatggctg ctagaatgta caaatagaac tagaggtttc taaattacga
     1921 atgctattaa ccaaacgaga agaacaatta ttgaaggctt tcctacatgt agggaagctt
     1981 tcaatgcaag atatgactga aatcttacag gtttcatcta gaacaattta tcgaacttta
     2041 tcagatttga cagatagcat ggagcaatat ggaatcgaaa taacgaagca tgggaaatac
     2101 tatattttga ctggagagtt ggatgatttg ccgacagaac ttgaagtgtt agttgagtat
     2161 agtccccaag aaagacaaga gttgattacc tatcgccttc tgactgagag tggttttgtc
     2221 accaatgaag cattgcaaga gtgcacgaaa gtcagtaatg taactattat tcaggatatt
     2281 tcagatattg ataagcgtct tttagacttt gatctgaaaa ttgaacgaca aaaaggttat
     2341 cggatttctg gtgattcagt tggtaagaga agatttttgg ctattttact gacaaactgt
     2401 atctcagtag cagatttttc aaccggtaat tttgggagct ttgatatttt agaagcagat
     2461 agaactaggc tggccagtca gattgttaat aagcaactgt caggttttcc agatatggat
     2521 gctaggatga agatgttttt tgcgatcttg ttatctctta taggtcagga gcaaaacatt
     2581 gaaaattcac ctaatactag taagcaggct ttggaaattt ctcaaaaaat ttttcaaact
     2641 tactctaagc agactgcaca attttatagt attcaggaaa ttatctattt tgcgagcatc
     2701 ttggatgaat taatcattaa acgtcaggac aatccgctct ttacggagaa atttgatggt
     2761 gaatttttct acaatatttc aaatctgatt gatacggttt ccatgtatac caagattgac
     2821 ttttttaagg acaaggtttt attcaatttt cttttccatc atattcggct cagtttaggc
     2881 gtccctatcc tttttcaggg tgaaaatttg ccagaatctg tccagatttt agttgaaagg
     2941 aataaatttc tttatacagt catcagtctt ttagtgaatg atatttttcc gaaatatctt
     3001 catacagagt atgagtatgg catgattgcc ctacatttta tctctagctt aggccgtagt
     3061 ccagagattt atccagtccg tgttttgctt ttaacggatg aacgtcgggt cactagagat
     3121 ttattagtca gtaaaattaa gagtgttgct ccttttgtag agttgataga tattcagtct
     3181 ctagtagatt accacagtat tgatctcagt cagtatgatt atattttatc taccaagccg
     3241 ctgactaatc aggaaatcga tgtaatttct agttttccaa ccgtcaaaga attgcttgaa
     3301 ttacaggaac gacttcagta tgtacaggca catcgtacaa ttgtcgcgcg tgatgctatc
     3361 gctccagaga aaagttatga cttgcaagat tatttaatat ctagtagtca gcttttgagt
     3421 caattcgagt tggttcaatt ggagaataat caatcatttg agcacacggt agaacaaatc
     3481 atccaatatc agaagaatgt gagtgacaga gattacctaa caagaaaatt gttatctcac
     3541 ttccagaata gtcctatggc tattcctaat actggtctgg tgcttttaca tagtcagtct
     3601 agcaaagtaa caacaaatag ttttactatg tttgaactca aactacctat ctccgcattg
     3661 tcaatgaaac tagaggaaga agaggtcaaa aggtgtctgc taatgctaat gtctaaagaa
     3721 gctagcgagg aagcgagaga tttaatgaca gctattagtc agtcgattat tgaaaatcat
     3781 ctttatacag agatttacaa gacgggaaat caatccatta tttatcagat gctaaatact
     3841 atttttaacg aaaaaattaa gaaattggag aactaatatg aaacttgaaa aacatttgat
     3901 taagcttaat aaacaatttt ctaacaagga ggaagctatt tgttattgtg ggcaagttct
     3961 ttatgagggt ggatatgtta atgaagacta tattgaagcc atgattgagc gagataaaga
     4021 gctatctgtt tacatgggta actttatcgc cataccgcat gggacagatg cagcaaaaaa
     4081 tgatgtcctc aagtctggta ttacagtcgt tcaagtccct agaggggttg attttgggaa
     4141 tgtatctaac cctcaagtgg caacggttct ttttggtatt gctggtattg gtaatgaaca
     4201 cttagaaatt attcagaaaa tttctatctt ctgtgcagat gtagataatg ttcttaaact
     4261 agcagatgct cagtcaaaag aggaagtatt gcgcttattt gatgctgttg aataattgaa
     4321 tttcgtcatt tgtcatctag tatatatgtc cctcaaatag gaaaaggaga aattgaatga
     4381 aacattctgt tcattttggt gccggtaata tcggtcgtgg ttttataggt gaaattctat
     4441 ttaaaaatgg tttccatatt gattttgtgg atgtcaataa tcagataatt catgctctaa
     4501 atgaaaaggg caagtatgaa attgaaattg cacagaaagg acagtctcgt atagaagtaa
     4561 ctaatgtggc tggcattaat agcaaagaac atcctgagca agtcattgaa gcgattcaaa
     4621 agacggatat tattactact gcaatcggac ctaatatact cccttttatc gccgaacttc
     4681 tagccaaagg aatcgaagct cgccgagttg caggaaatac acaggcattg gatgttatgg
     4741 cctgtgaaaa tatgattggc gggtctcaat ttctttatca agaagtcaag aaatatttaa
     4801 gtccggaagg tttgacattt gctgataact acataggttt tccaaatgct gcagtagaca
     4861 ggattgttcc agcacaaagt cacgaagatt ccctttttgt tgtggtcgag ccctttaatg
     4921 aatgggtcgt ggaaaccaag cgtcttaaaa atccagattt acgtctaaaa gatgtgcatt
     4981 atgaagaaga tttagaaccc tttattgagc gaaaactttt ttcagtcaat tctggacatg
     5041 caacttcagc ttacattggt gcgcattatg gtgccaagac aattttggaa gctcttcaaa
     5101 atcctaatat caaatctcgg attgaatctg tattagctga aattcggagt ctcttgattg
     5161 ccaaatggaa ctttgataaa aaagaattgg agaattatca caaagtcatt atagaacggt
     5221 ttgaaaatcc tttcatagtg gacgaggtta gtcgcgtagc tcgtactcca atccgaaaat
     5281 taggctataa tgaacgattc atccggccga tacgtgaatt gaaagaactc agtttgtcat
     5341 ataaaaacct acttaaaaca gttggctatg cctttgacta tcgcgatgta aatgatgaag
     5401 aaagtattcg attaggtgaa ttgttggcta aacaatcagt caaagatgtt gttatacaag
     5461 ttacaggttt agacgaccaa gaattgattg agcaaattgt agagtatatt taatcttttt
     5521 cgaaaatctc ttcaaatcag gttagcatcg ctttgtctta ggcatatgtt gttctatcta
     5581 caacctcaaa gcagtgcttt gagctgactc cgtcagtctt atctgcaatc tcaaaacact
     5641 gtttgagtta tctgcggtaa tctttctagc ttgtctttga tttttgttgt tatttataag
     5701 gtaaaagaag ctggacaaaa agtcttcaaa atcgggaaaa ggcagcctat cgggtgttca
     5761 aaaatcttga taggatgtcc tttattatgg aaagccttat tggattttct cctcagattg
     5821 agtttttgat cagctttatg agataggtct tgctagagat gtagcccatc atgttatttt
     5881 tatggacagt gggaaaattg ttgaaaaaaa taatgcccat caattcttta gtcgtccaag
     5941 agaagaacga accaagcaat tttggaacga attctttcga atgcgatcta tatagtaaaa
     6001 tgaaacaaga
//
LOCUS       DAVLTG010000080         5868 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLTG010000080 DAVLTG010000000
VERSION     DAVLTG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.081"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            105..584
                     /locus_tag="VYN12_001930"
     CDS             105..584
                     /locus_tag="VYN12_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1416239.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VYN12_001931"
     tRNA            678..749
                     /locus_tag="VYN12_001931"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1001..2546
                     /locus_tag="VYN12_001932"
     rRNA            1001..2546
                     /locus_tag="VYN12_001932"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2598..2670
                     /locus_tag="VYN12_001933"
     tRNA            2598..2670
                     /locus_tag="VYN12_001933"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2631..2633,aa:Ala,seq:tgc)
     gene            2795..5696
                     /locus_tag="VYN12_001934"
     rRNA            2795..5696
                     /locus_tag="VYN12_001934"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5773..>5868
                     /gene="rrf"
                     /locus_tag="VYN12_001935"
     rRNA            5773..>5868
                     /gene="rrf"
                     /locus_tag="VYN12_001935"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1724 a         1138 c         1676 g         1330 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggagcaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caagaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aaacaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ttagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc gtcaggacca cttgatgaaa
      781 aaaagtttaa aaaagcttaa aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaca
      961 ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga gtttgatcct
     1021 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
     1081 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
     1141 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
     1201 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
     1261 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
     1321 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
     1381 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
     1441 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
     1501 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
     1561 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
     1621 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
     1681 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1741 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1801 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1861 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1921 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1981 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagctt tccttcggga
     2041 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     2101 cccgcaacga gcgcaacccc tattgttagt tgccatcatt cagttgggca ctctagcgag
     2161 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     2221 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     2281 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     2341 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     2401 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     2461 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     2521 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     2581 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     2641 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     2701 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2761 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2821 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2881 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2941 acctacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     3001 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     3061 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     3121 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     3181 acttagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     3241 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     3301 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     3361 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     3421 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     3481 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     3541 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     3601 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     3661 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3721 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3781 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3841 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3901 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3961 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     4021 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     4081 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     4141 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     4201 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     4261 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     4321 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     4381 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     4441 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     4501 aaatgacccc gtaacttcgg gagaaggggt gctgacttaa agtcagccgc agtgaatagg
     4561 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     4621 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     4681 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4741 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4801 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4861 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4921 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4981 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     5041 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     5101 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     5161 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     5221 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     5281 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     5341 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     5401 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     5461 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     5521 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     5581 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     5641 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     5701 actgagaata tgaaagcgaa cggttttctt aagttgaata gatattcaat tttgagtagg
     5761 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5821 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DAVLTG010000081         5478 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLTG010000081 DAVLTG010000000
VERSION     DAVLTG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.082"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(59..358)
                     /locus_tag="VYN12_001936"
     CDS             complement(59..358)
                     /locus_tag="VYN12_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1416240.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            760..1464
                     /locus_tag="VYN12_001937"
     CDS             760..1464
                     /locus_tag="VYN12_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1416241.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    1523..1610
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            1646..1960
                     /gene="rplU"
                     /locus_tag="VYN12_001938"
     CDS             1646..1960
                     /gene="rplU"
                     /locus_tag="VYN12_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1416242.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            1976..2320
                     /locus_tag="VYN12_001939"
     CDS             1976..2320
                     /locus_tag="VYN12_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1416243.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            2337..2630
                     /gene="rpmA"
                     /locus_tag="VYN12_001940"
     CDS             2337..2630
                     /gene="rpmA"
                     /locus_tag="VYN12_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1416244.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(2941..3146)
                     /locus_tag="VYN12_001941"
                     /pseudo
     CDS             complement(2941..3146)
                     /locus_tag="VYN12_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            3583..4500
                     /locus_tag="VYN12_001942"
     CDS             3583..4500
                     /locus_tag="VYN12_001942"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1416245.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(4593..5441)
                     /locus_tag="VYN12_001943"
     CDS             complement(4593..5441)
                     /locus_tag="VYN12_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1416246.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
BASE COUNT         1704 a          933 c         1103 g         1738 t
ORIGIN      
        1 catttttgca cctttcttag cctttgttat cgacaagcat tgttctagct ccttgttttt
       61 agaaaggtaa tttcccagcg aaagcaccca gttttttctt ggtagtttca tcgatttgtt
      121 caagagcaga gttgatggct tgaacggtca tatcagaaag agtctcaagg tcctctgggt
      181 caacgacagc tggattgaaa tcaatgctga caactttctt atcgccagtt aaggtcgctt
      241 ggacaagatc ttgagcagat ttgccaacaa attgcatagc agcaagttca gcttggcttt
      301 gttccatttg tttttgaagt ttttgtgctt gacgcatcat gttttgcatg ttcatcataa
      361 gatttctaaa gttcctttca tctcaagggg ataatccttg ttgttaacaa gtgcctgatt
      421 ttctctccta attgttatta gtagcatagc catcaagccc aagtattgat tttattatac
      481 cattttttta agacatagtc ttttattggt gagagttatt tatgtcaagg agtgattaga
      541 aataaattaa aataatgatt tttgctaaga gggctctatt ctagtttcat ggaaatgatt
      601 ttactaaagg ttcgtatgct ttgtttgcaa acatgttaca tctatctatt tttggataaa
      661 tagttgtcta ttattatttt tatgctaata gtaaaatcta aatggtagcc tacgattttt
      721 tagaaagaaa atggtacaat atttctaaga gaaaatacaa tgggaggtaa aatgaggtta
      781 ttacctataa gaaaaatatc acgtcagtct aaaaggttag cacttttttt gacgttttgt
      841 gctggatatg tggatgctta cacttttatt gttcgcggga atacccttgt agctggacaa
      901 actggaaatg ttgtctttct ttcagtagaa ttaattaaaa ataatgtttc ggatgttagg
      961 gacaaggttc tcaccttgct agcgtttatg atgggagtct ttttattaac gatttataag
     1021 gaaaaattga gaattgtgaa aaaacctatt ctgtccttga ttcccttggc aatcttatca
     1081 atcattattg cttttgtgcc gcaaactgtg gataatatct atctagtgcc gcccttggcc
     1141 ttctgtatgg gactggtgac aactgctttt ggagaagtgt cgggtattgc ctataataac
     1201 gcttttatga cagggaatat caaacggacc atgctggctt ttggagatta tttccgaacc
     1261 aagcacactc cttttttgcg tgaaggattc atatttgtta gcctgcttag tagttttgtc
     1321 cttggcgttg tcttttcagc ctatttgacg attttctatc atgaaaagac cattcttggt
     1381 gttcctatta tgatgagcgt tttttacctc agcatgcttt ttgcctcttg gcagaaaaaa
     1441 gtaaaagaaa aagcttcatt ttaggtgtta ttacttgtaa gaaaatagga gatatgctat
     1501 acttgaagag ttgactatgc acgatcctgt gcaaccgcac gaacatcgtt gcttgattat
     1561 tcaagtttaa gtggttcgtc ccacgatgct aggcgagtct tcacaaaaaa tcggggaaac
     1621 ccataaaaat cataggaggt gcataatgag cacatacgca attatcaaaa ctggcggaaa
     1681 acaagttaaa gttgaagttg gtcaagcagt ttacgttgaa aaattgaacg ttgaagctgg
     1741 tcaagaagtt acttttaacg aagttgttct tgttggtggt gaaaacactg ttgtcggaac
     1801 tccacttgtt gctggagcta ctgtagttgg aactgttgaa aaacaaggaa aacaaaagaa
     1861 agtggttact tacaagtaca aacctaaaaa aggtagccac cgtaaacaag gtcaccgtca
     1921 accatataca aaagttgtca tcaacgcaat caacgcttaa ttttaaggag aacacatgat
     1981 acaggcagtc tttgagagag ccgaagatgg cgagctgagg agtgcggaaa ttactggaca
     2041 cgccgagagt ggcgaatacg gcttagatgt cgtgtgtgca tcggtttcta cgcttgccat
     2101 taactttatc aattctattg agaaatttgc aggctatgaa ccaatcctag aattaaacga
     2161 agatgaaggt ggctatctga tggttgaaat accaaaagat cttccttcac accagagaga
     2221 aatgacccag ttattctttg aatcattttt cttaggtatg gcaaacttat cggagaacta
     2281 ttctgagttc gtccaaacca gagttatcac agaaaactaa cacggaggaa aacattatgt
     2341 taaaaatgac tcttaacaac ttgcaacttt tcgcccacaa aaaaggtgga ggttctacat
     2401 caaacggacg tgattcacaa gcaaaacgtc ttggagctaa agcagctgac ggacaaactg
     2461 taacaggtgg atcaatcctt taccgtcaac gtggtacaca catctatcca ggtgtaaacg
     2521 ttggtcgtgg tggagacgat actttgttcg ctaaagttga aggcgtagta cgctttgaac
     2581 gtaaaggacg cgataaaaaa caagtttctg tttacccaat cgcaaaataa aaaggttcat
     2641 tgaacctttt atcccgaacc ttgaaatgta aaggtgagga agctagaaac agcttaaaat
     2701 aaggctttcc gagttttcgg agagcctgtt tttttatttt gatacccata ctttttaata
     2761 tgtatagtgg attgatactc ttcgaaaatc aaattcaaac cacgtcaatt tcaccttgcc
     2821 gtactcaagt acagcctgcg gctaacttcc tagtttgcac tttaattttc attgagtatg
     2881 aatctggaat agaacactgt taaaaattga tatgagtttc ctactcgatt tcttcagatt
     2941 ttatttcaat tgactataag aactgctatc tggtttcaaa tattggcttg tcgtcccttc
     3001 acttgtctga atggtttgag ccgttccttc tgataaggga aaagatattc tttagctgaa
     3061 acggtctgag aatccaagct aacagatgga gagaaaaata gcccagtctg aagcacacta
     3121 gatgggagtt gttggaaagc agtcatctag tttttctttg ctgttttggc ttttttcttt
     3181 gtcatcaggg aaagtgactt gcttcaaatc agggagttta ggaaattctt caaacatctt
     3241 gcccaagttg tctcattttg taaattttac agccataggt gtacctcgat tctaaattct
     3301 acctttttgg caccaattag taatttaaag ttctcaggag ttagttgcat tgctttttca
     3361 tacataacat agtatgacac tttatggtta ccgaacaagt ctaatcactc cttgcaaaat
     3421 tttgaagatg tcctacaagt ttttgagaag aatattgcaa agttcatagt taagcaacga
     3481 tagaataaag tgctttttga aaacaggtac acttcatgtg aaaaaaacaa catttcagat
     3541 tttctgttcc agaaatagct atcgctatga tataattatt ttatgattat tactattcct
     3601 ataaaaaacc aaaaagatat tggcacacca tctgattcag tcgttgttct cggctatttt
     3661 gatggcatac ataaggggca tcaagaatta tttcgtgttg ccaacaaggc tgcgagaaag
     3721 gatttattgc ctatcgtcgt tatgaccttt aatgaatctc caaagatcgc tttagagcct
     3781 tatcatccag atttgttttt gcatattttg aaccctgctg aacgtgaaag aaaattaaag
     3841 cgcgaaggtg tagaagaatt atatctcctt gattttagta gtcaattcgc tagtctcact
     3901 gcacaagaat tctttgcaac ttatatcaag gctatgaatg ccaaaattat tgttgcaggt
     3961 tttgattata catttggttc tgacaaaaaa acagcagaag atttaaagga ttactttgat
     4021 ggagaagtta tcattgttcc acctgtagaa gatgagaaag gaaagattag ttcaactcgt
     4081 atccgtcaag ctattttaga tggaaatgtg aaagaagcag gaaaactttt gggggcaccg
     4141 cttccatcaa gaggtatggt ggttcatggt aatgctcgtg gtcgtacaat tggttatccg
     4201 acagcgaatt tagtgctttt agaccgtact tatatgccag cagatggcgt ttatgtcgtt
     4261 gatgttgaga ttcaaagaca gaagtatcgt gctatggcta gtgtcgggaa aaatgtgacc
     4321 tttgatggag aagaagcacg ttttgaagtc aatatttttg attttaatca agatatttat
     4381 ggggaaaccg tcatggttta ttggcttgat cgcattcgtg atatgaccaa atttgactca
     4441 gttgaccaat tagtggatca gttaaaggct gatgaagaag taactcggaa ttggtcttaa
     4501 gagcttgagt aaataaaaca aaaaagaggt tgtctgtaac ccaaaagata gatgatttag
     4561 tctaactttt gaggtcacga cattacctct ttttattctt tttcaaaggt gaagccttct
     4621 cctaggattt catgggcttc tgtaatagtt ataaaggctt gaggatcgat tcgatgaatc
     4681 atttccttcg ttttcacaat ttcatttctt ccgacaatac agtagatgat tttcaaattt
     4741 tctttactat agtagccttg accagaaata aaagtaacac ctcttccgag gtcatcatta
     4801 atcgccttag caagttggtc aggacgtttt gtgataatca taaagccttt gccggcatat
     4861 cctccttcac caatcaaatc aataacacga gaaacaataa aatcaaacaa aagcgtgtag
     4921 gaaaccaatc tcaaatcctt gaagattagg agaatcaaca tgagaataca aaaatctaag
     4981 ataaagagca gttttcctat ggatatatga gtgtatttgt tgagaatacg agctagaata
     5041 tcagttccgc cagttgtacc tccagcatta aaaataattc caaggccaat tcccaatagg
     5101 attcccgcta taagggctgt gattagtaaa tcaccttgaa gatcaatatg aaggggaata
     5161 tgctcaaaaa aagctaacca ggcggacaaa gctaaggttc ctagtaaact agaatagagg
     5221 gatttggctc caaagatctt ccaagctagg atgaaaaggg gaatattaat cagcaggttc
     5281 atgagggaaa cagggatttt aaaaagataa aaggtgatga gggtaatgcc tgtcgcccct
     5341 ccttcaaaga gatgatgggg aactacaaaa taagtcagtc caaaagcata aatagcagca
     5401 cctagtaaaa tggtaaaaat ggggtaaatt tttttaatca taggacacct cttttcttat
     5461 aagttgatta tatcaaat
//
LOCUS       DAVLTG010000082         5437 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLTG010000082 DAVLTG010000000
VERSION     DAVLTG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.083"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            84..272
                     /locus_tag="VYN12_001944"
     CDS             84..272
                     /locus_tag="VYN12_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1416247.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            334..1149
                     /locus_tag="VYN12_001945"
     CDS             334..1149
                     /locus_tag="VYN12_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1416248.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNETHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKMKFLKSNRMLFSKINMVDNQYKKHQNEQGGI"
     gene            1149..2003
                     /locus_tag="VYN12_001946"
     CDS             1149..2003
                     /locus_tag="VYN12_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1416249.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2115..2999
                     /locus_tag="VYN12_001947"
     CDS             2115..2999
                     /locus_tag="VYN12_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1416250.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            3162..4901
                     /locus_tag="VYN12_001948"
     CDS             3162..4901
                     /locus_tag="VYN12_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV1416251.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIWKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            5176..>5437
                     /locus_tag="VYN12_001949"
     CDS             5176..>5437
                     /locus_tag="VYN12_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416252.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSENLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYE"
BASE COUNT         1805 a          819 c         1156 g         1657 t
ORIGIN      
        1 tctccacttt taaactaatg tattataaaa gccagttgac acaagtgtta cacctgtgat
       61 agaattaact tgaggtgatg aaaatggcaa ccgataaaaa tagaataatg attagcttgg
      121 atgataaaaa tctagagaaa cttgaaaatt tagtagaaga tgctagagat agaaggggaa
      181 tgcgactaac aaagtcccag gttattgaat tactcctaaa taccgttgat tatttcgatg
      241 atattatggg ggctatttac tcaaaaaaat aagagcaaaa ttgctattat tttttacaaa
      301 ttggtgtaac actagtgata taggagtgat gaaatggttg tttatattag acaaagtaaa
      361 ttaccaagtg aggtttcaat taataaatac catgctcaag taggtgccta cttacaagga
      421 gaagaagtta ttttatatca atctttttct gaaataaaag agttaacaag tgaagatata
      481 gttgtagatt atataatgga gactagagca ttactaaaaa tgatgggctt aaacgttccg
      541 gtttatgact atcctattga gcttaaagag ttttatggtc gaaagattta tgctggtatt
      601 ttaggagaga ttgtgaatat acctgataat tggggaaaat ttattaagcc taaagctggt
      661 tcaaaagtct ttactggaag agttgttaat gaaacccatg atttaatagg tattggtcta
      721 cctttcgact atcctatatg gattagtgag gttgtagaat tcatagctga atggcgttgt
      781 tttgtgttag atggtcgcgt attagatgtt cgaccctata caggtgatta tcatgcacaa
      841 tttgatgcaa gtgtaattga tgaagcgata tcatgttgga aagatgcgcc aatagcttat
      901 ggactagata tcggtgttac tcgcgatggc agaacacttg ttgttgaagt aaatgatggt
      961 tatgcattgg gaaattatgg cctatctcct ttaaaatcaa tcaattttca tagagctagg
     1021 tggaaagaaa tggtaaaacc ctattttgaa aaaatgaaat ttttaaaatc caacaggatg
     1081 ttattttcta aaataaatat ggtagataac caatataaaa agcatcaaaa tgaacaagga
     1141 ggaatctgat gcttggagca attattggag atattgtcgg ttctgtttac gaatggaaca
     1201 atatcaaaac aaaggacttt cctttatttc ggaaggactg cttttttaca gatgacacgg
     1261 ttatgacctg tgctgttgca gaagcaatta tgaatggtgg acaaaaagac gatttcattg
     1321 acgcgatgaa gaaatatggc agaatgtatc cgaatgctga ttacggtgct cggtttaatg
     1381 catggctaaa cagcgataac cgtgagcctt ataatagctt tgggaatgga tcagctatgc
     1441 gtatttctcc atgtgcttgg atcatggact gtggttttta tgcgaaaact ggtatgtggc
     1501 catcatctag aggacttacg agtctttctg cagaggtaac tcataatcat ccagaaggtg
     1561 tcaaaggcgc tatggctaca gctgatgcta tctttctatg tcgtttttac tttggtggtt
     1621 attgtagaga gtacgagcaa tcaattaacg acaatcctac agagtgtaaa agacgaatta
     1681 aggattatat agaaaaagaa tacgattaca atctatctca aactttagat gaaatccgtc
     1741 ctaactatcg ttttaacgaa acatgtcagg aaactgtccc tcaagccatt atcgcctttc
     1801 ttgaaagtag agacttcgaa gatgcgataa gaaatgccat ctcacttggt ggcgacagtg
     1861 atactctcgc agcaatcact tgtagcatag cagaggcagc ttacggtatt cctgattgga
     1921 tcaaggataa ggcctattct tacttggatg aacccttaaa ggatgtagtt aggcgatggg
     1981 aaaatagaat aaaagcgtat taatctccag tacgtcagat ttctcttttc tgtattttca
     2041 ttgtataata ggattacatt tacttgcatg cgacgaaatg taaacatttc tgtttaaaat
     2101 taaggataaa atcaatgaaa aaagcaatgg taattatcaa ccctacttct ggtggcgaga
     2161 aggctttgga ttacaaagaa aagctggaga ataaagcaaa agaatacttt gaatatgttg
     2221 aaaccaaaat taccgaaaaa gcgctggatg caacacattt tgctgaagaa gcttctcgtg
     2281 agcagtatga tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa gtcatttcag
     2341 gtattgatga gagagactac attcctaagt tagggattat cccaggcggt acgggtaacc
     2401 tcattacaaa acttttggaa atcaatcaag acatcgatgg cgcaattgac gaactggatt
     2461 ttgatttaac caataagatt gatatcggta aagcaaatga caactatttt ggttatatct
     2521 ttagtatcgg ttctctgcct gaggcgattc acaatgttga aatagaggac aaaacaaaat
     2581 tcggtatttt aacctatgct gtaaatacca tgaagtctgt catgacagat caggtcttta
     2641 acattaaggt tgagacagaa aatggaaatt atgttggtga agctagccat gttttggtcc
     2701 ttttgacaaa ttacttcgct gataagaaaa tctttgaaga aaacaaggac ggctatgcca
     2761 acattttgat tctgaaagat gcctctatat tctccaaatt atccgtcatt cctgatttat
     2821 taaaagggga tgttgtcgca aatgataata tcgagtatat caaagcgcgt aatattaaaa
     2881 tctcttcaga tagtgaattg gagtcagatg ttgacggaga taaatcagat aacctacctg
     2941 tagaaatcaa agtcctagct cagcgagtag aagtattttc aaaaccgaaa gaggattagt
     3001 atatagagaa agtctttttt aaggcttttt gtatacttta aaagatagtt cctttaacaa
     3061 cggacattcc ttgcaaatag tttacaaaaa tagtatactg gatttattga gtttgaaaac
     3121 gtttgcgtaa aatttgaatg aatactttag gagacaaatt gatggaattg agtgctattt
     3181 accataggcc tgagtcggag tatgcctatc tttataagga taagaaactc catattcgaa
     3241 ttcgaactaa gaaaggggac attgaaagca tcaacttgca ctatggggac ccttttatct
     3301 ttatggagga gttttatcag gatacaaaag aaatggtcaa gataacttct ggtaccttat
     3361 ttgaccattg gcaggttgaa gtgtcagttg actttgcacg tatccagtat ctctttgagc
     3421 tcagagatac agaaggtcaa aatattttgt atggcgataa agggtgtgtg gaaaattctc
     3481 tagaaaatct tcatgcaatt gggaatggat ttaagttgcc ttatcttcat gagattgatg
     3541 cctgcaaggt tcctgactgg gtttcaaata cggtatggta tcagatattt cctgaaagat
     3601 ttgccaatgg caatgctcta ttaaacccag aagggacttt agactgggat tcatctgtca
     3661 cacctaagag cgatgatttc tttggtggtg atttacaggg gattattgat catatggatt
     3721 acttgcaaga cttgggtatt actggactat atctttgtcc catctttgaa tctacaagca
     3781 atcacaagta caatacgaca gattactttg aaattgaccg tcattttgga gacaaggaga
     3841 cctttcggga actggtggat caagcgcatc atcgtggcat gaaagtcatg ctggatgcgg
     3901 tatttaatca tattggttcg caatctcttc aatggaaaaa tgtcgtcaaa aatggtgaac
     3961 agtctgctta taaggattgg ttccatattc aacaattccc agtgacaact gaaaagctag
     4021 ttaataagag agacttaccc tatcatgttt ttggtttcga ggactatatg cctaagctaa
     4081 atacagccaa tccagaggtc aagaattatc ttttaaaggt tgcgacttat tggattgaag
     4141 agtttaatat cgatgcttgg cgtttggatg tggctaatga gattgaccat cagttctgga
     4201 aggattttcg taaggcagtt ttagctaaaa atcctgatct ttatatccta ggagaagtct
     4261 ggcatacatc tcagccttgg ctaaatggag atgagttcca tgccgtcatg aattatcctt
     4321 tatctgatag tatcaaggac tatttcttac gaggaattaa gaagacagac cagttcatcg
     4381 atgaaatcaa tggagagtct atgtattaca agcagcagat ttcagaggtc atgtttaatc
     4441 tcttggattc acatgataca gagcgaatcc tgtggacggc caatgaagat gttcaactgg
     4501 ttaaatcagc cttagccttt ctctttttac aaaaaggaac accgtgcatt tattacggaa
     4561 ccgagctagc cttgactgga ggaccagatc cagattgtcg tcgttgtatg ccttgggaac
     4621 gtgtatcaag tgacaatgat atgctgaact ttatgaagag gctgattaag atttggaaat
     4681 acgcgtcagt aatcatttcg catggcaagt atagccttca agaaatcaaa tctgatctag
     4741 tagctctgga atggaaatac gaaggacgga tcctcaaagc aatattcaac caatcaacag
     4801 aagattatct tttagagaaa gaagcagtag cactagcaag caattgccaa gaattggaga
     4861 atcagcttgt catctctcca gatggatttg tgattttcta aaaactagtt gatgaagatt
     4921 atggtacatt tcatatctta tatagtataa taaggctagt tactaaactt gtaaaggaga
     4981 acttaaatga attgtagagg acatgaaaca agacaaagaa ttgttagaga ttttgaagtt
     5041 tagcctaaag cacatattaa gctgttagca aatcaacaaa aacatagtga tgcaggagca
     5101 actattgaag atgaatatta tgtatttatc gctgagagta aaattgatgg caagaaggaa
     5161 gttattcagt gttgcatggg tgcggcaagg gattttttag aactaattaa tcacaaaggg
     5221 ctacctcttt ttaatccgct tgtaggtgat tctcatgtaa ataatagaca agaatatgac
     5281 aatacaggga gtgaaaattt acaacctgaa aagtggaatg aaactgcaaa gcagctttat
     5341 aatgctataa tgtggttgat tattttatgg aatgctaagc cggatacacc tttatttaat
     5401 tttaaagacg aagtaattaa gtataaaaca tatgagc
//
LOCUS       DAVLTG010000083         5269 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLTG010000083 DAVLTG010000000
VERSION     DAVLTG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.084"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..399
                     /locus_tag="VYN12_001950"
     CDS             <1..399
                     /locus_tag="VYN12_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1416253.1"
                     /translation="SEIIAYNLSTSPNLEQVQTMLEQAFKEKHYENTILHSDQGWQYQ
                     HDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAI
                     VDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(515..1318)
                     /locus_tag="VYN12_001951"
     CDS             complement(515..1318)
                     /locus_tag="VYN12_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1416254.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1595..2350)
                     /locus_tag="VYN12_001952"
     CDS             complement(1595..2350)
                     /locus_tag="VYN12_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1416255.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKL
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2420..5071)
                     /locus_tag="VYN12_001953"
     CDS             complement(2420..5071)
                     /locus_tag="VYN12_001953"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1416256.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(5083..>5269)
                     /locus_tag="VYN12_001954"
     CDS             complement(5083..>5269)
                     /locus_tag="VYN12_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1416257.1"
                     /translation="SKLESLKLKHSRYYISKISKYDLKYNPGNYTMSPLAAFAEIEEI
                     YIELSKIGLVKIVNKSN"
BASE COUNT         1551 a         1123 c         1015 g         1580 t
ORIGIN      
        1 agcgaaatta tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg
       61 ttggaacagg cattcaaaga gaagcactac gagaatacga ttctccatag tgaccaaggc
      121 tggcaatatc aacacgattc ttatcatcgg ttcctagaga gtaagggaat tcaagcatct
      181 atgtcacgta aaggtaacag cccagacaac ggtatgatgg agtccttctt tggcattctg
      241 aaatcggaga tgttttatgg ttatgagaag tcatttcagt cgcttaagca attggaacaa
      301 gccattgtag actatattga ttactacaac aataagagaa ttaaggtaaa actaaaagga
      361 cttagccctg tgcaatacag aactaaatcc ttcggataaa ttatttgtct aacttttggg
      421 gggcagtaca ttttaacact tgatactatg cgttttattg tgggaatgtt tgcttcattt
      481 tttcctaaaa ttcaatgttt actcagtatt tggattatga aaaatcgagg tctaaatcta
      541 gatacatttt ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag
      601 ctgttaaaaa ctcaggacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac
      661 gaaaatattt ggaatgttgc tgaaatggta tattatcaat atcaaaacca aactcacgaa
      721 gatactgaat caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct
      781 gccagattcc tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg
      841 catatgcaac ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt
      901 aatcagagta cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct
      961 gacgaaattg ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa
     1021 tagcaagtaa ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac
     1081 gtagagaaac caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg
     1141 catcctcata aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt
     1201 ccatatacgc tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata
     1261 aatcacgctt cgcttcataa gacaagtttg gattgtcaat gttgtaagtt ggttgcatag
     1321 aaatatcctt tcaattgttt ttcttcatta ccagtaaatc acgaaattgg ttggaaactg
     1381 gcttaaacta taaaaagtcc tcacaatagg ttctatgata tatatatata cttcatgtaa
     1441 ataataaaag agttataatc agcactactg ataaattcaa taccgatttc gccatcttaa
     1501 aacttagtca aacgaatacc gttgatttcc agttcattaa gtcgttgacc tgtcaagact
     1561 tctcgttcct tcaactggaa aagttaaggg ggaactaata caaatcctct acgcttctat
     1621 attcaatgat ttcatttttt ataatattct ttttaaactc aaaatgtttt agaggattat
     1681 caactaatac taactttgga atatcatcta ggttggtgac cagagataaa ataaaatctg
     1741 attgaaactc tttagctttc tcaaattcgt aggcagttaa acggacacga cccttaggtt
     1801 ttcgaatccc tttaacttcg gcaaggtagg aatgttcttg aatatctact tggaaatcat
     1861 atccatcacc ataaagacat gcatcggtta actgtccacc ttgaaatttt tcttctttat
     1921 caaaatgaag gataaaataa ttctctgcct ccatccccgt ttcctgtaga cgtttgaatt
     1981 tagttcgaat aattggtttt tcaattatag taatgcctgt ttgctttcct tcactagcaa
     2041 gtaacagttt aacaatttca acataactat gaacatcttc atttccaaac atcatatcaa
     2101 ttaaatcttt acgaaaacgg taaacttcag ctttctgcca ccaacctttt cgactattgt
     2161 caaaataagg atcaaataaa tccattctat tttttacaac tccagttgtt tcagcaattc
     2221 ccagagaaac cacatagcga taaaactccg acttgctaga gcattgaaat tcttttataa
     2281 aaagcttgtc aaacttggca agaccgtagc caattaaatt taacaattca taatgagggt
     2341 gtttggacat cactttctcc atcaatagat attgatttca ttataccaaa aaacacggct
     2401 catcaccgtg tttctgtgtt tatttcacca acttcttcat ctcatcaata cgtgctacgg
     2461 tcacatcata cttggcttgg tagtcggctt gtttgtcttt ttctttttgg acaacttctg
     2521 gtttagcgtt ggcgacgaag cgttcgttgc tgagtttttt gccaaccatg tcgagttctt
     2581 tctgccattt ggcaagttct ttttccagac gtgccaattc ttcttcgaca ttcaagaggt
     2641 ctaccagtgg caagaagatt tcggctcctg taataacgct tgacatagcc agttcaggtg
     2701 cagggatggt tgatgcgatt tccaagtgtt ctggatttgt aaagcgtttg atatagttga
     2761 cattgctgtt aaagaaggct tccaagtcgc tatcgcttgt cttaacaagg atggtgatag
     2821 gcttgcttgg tgctacattt acttccgcac gcgcattccg aacagcacga atcaagtctt
     2881 tgagactttc cacaccagtg tgagccgcaa ggtcttcaaa ggctagatta acagttgggt
     2941 atgcagctgt cacgatagaa ccttctgaga tttgtccaaa gatttcctct gtcacgaatg
     3001 gcatgattgg gtgaaggaga cgaaggatct tgtccagcgt atagaggaga acagatcgag
     3061 taatgacctt atcgtcttca ttgtcgctgt atagaacttc cttggtcaac tcaacatacc
     3121 agttggcaaa ttcttcccag atgaagttgt aaaggatatg accagccaca ccaaactcga
     3181 acttatcaaa gttttcagta acttttgcaa tggtttcgtt gagattgtgg agaatccagc
     3241 ggtccgtcac attaccagcc tcacctgttg caacttttgt gacattgtca tgcgccacat
     3301 ccagcgtcaa accttcattg ttcatgagga tatagcgaga aatgttccaa attttgttaa
     3361 taaagttcca tgaagcatcc attttctcgt aagagaaacg aacgtcttga cctggtgcgg
     3421 aaccgtttga aaggaaccaa cgaagggcat cagcaccgta tttctcgatg acatccattg
     3481 ggtcaatccc gttaccgaga gatttagaca tcttgcgtcc ttgctcgtca cggatgagac
     3541 cgtggataag cacgttttgg aatggctgac gaccagtaaa ttccaaggac tggaagatca
     3601 tacgagatac ccagaagaag atgatgtcgt aacctgttac caaggttgaa gttgggaaat
     3661 aacgtttaaa gtcttctgag tcgacttcag gccagcccat ggttgaaaat ggccagaggg
     3721 cagaactgaa ccaagtatcc aagacgtctt cgtcctgagt ccatccgtca ccttctggag
     3781 cttcttcgcc gacatacatt tcaccatcag cattgtacca ggcagggatt tggtgacccc
     3841 accaaagctg acgagagata acccagtcgt ggacattttc catccattga aggaaggtat
     3901 cgttgaaacg aggtgggtag aattcgacct tgtcctctgt gtcttggtta gcaatggcgt
     3961 tcttagccaa ttggtccatc ttgacgaacc attgagtaga caagcgtggc tcaactacga
     4021 cacctgtacg ttctgagtga ccaacactgt ggacacgttt ttcgattttg acaagggcac
     4081 cgatttcttc caacttagca acgactgcct tacgagcttc aaaacgatcc atgcctgaaa
     4141 attcaaaggc aagctcattc atagttccgt cgtcgttcat gacgttgact tgtggcaagt
     4201 tatgacgttg gccaaccaag aagtcatttg gatcgtgggc aggtgtgatt ttcacgacac
     4261 cagtaccaag ctcaggatct gcgtgctcat ctccaacgat tgggatgagt ttattagcga
     4321 ttggaaggat gacgttttta ccaatcaagt ccttgtagcg cgggtcttct ggattaatcg
     4381 caaccgcaac gtccccaaac atagtctcag gacgagttgt agcaacttca agggcgcgtg
     4441 aaccatcttc cagcatgtaa ttcatgtggt agaaggcacc ttctacatcc ttgtgaatca
     4501 cctcaatatc agaaagggct gtgcgagctg ctgggtccca gttgatgata aactcaccac
     4561 gatagatcca gcctttcttg taaaggttca caaagacctt acgaacagct tttgacaaac
     4621 cttcatcaag agtgaaacgc tcacgagaat agtctacaga aagccccatc ttgccccatt
     4681 gttccttgat ggtagtggca tattcgtctt tccattccca gaccttcgtc aagaaagact
     4741 cacgacctag gtcataacgc gtaataccct caccacgtaa gcgctcctca accttagcct
     4801 gagtcgcaat accagcgtgg tccatacctg gaagccaaag ggtatcaaag ccttgcatgc
     4861 gtttttgacg gatgatgata tcctgcaaag tcgtatccca agcgtgacca aggtgaagtt
     4921 tcccagttac gtttggtggt ggaatcacga ttgaataagg cttagccttt tgatcgcctg
     4981 aaggcttgaa aacatccgca tcaagccatt tttggtaacg accagcctca acctcggctg
     5041 gattgtattt agatgaaagt tctttagaca tgtgtgttct ccttaattac ttttattgac
     5101 aattttaacc aaaccaattt ttgaaagttc aatataaatc tcttcaattt cagcaaatgc
     5161 tgcaagtggt gacatagtat aatttccagg attatattta agatcatact tgcttatctt
     5221 tgaaatataa tacctagagt gtttcaattt taatgattcc aactttgat
//
LOCUS       DAVLTG010000084         5233 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLTG010000084 DAVLTG010000000
VERSION     DAVLTG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.085"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            156..428
                     /gene="rpsP"
                     /locus_tag="VYN12_001955"
     CDS             156..428
                     /gene="rpsP"
                     /locus_tag="VYN12_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1416258.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            448..687
                     /locus_tag="VYN12_001956"
     CDS             448..687
                     /locus_tag="VYN12_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1416259.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            955..1159
                     /locus_tag="VYN12_001957"
                     /pseudo
     CDS             955..1159
                     /locus_tag="VYN12_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            1263..2012
                     /locus_tag="VYN12_001958"
     CDS             1263..2012
                     /locus_tag="VYN12_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1416260.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSE"
     gene            2082..2600
                     /gene="rimM"
                     /locus_tag="VYN12_001959"
     CDS             2082..2600
                     /gene="rimM"
                     /locus_tag="VYN12_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1416261.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            2590..3309
                     /gene="trmD"
                     /locus_tag="VYN12_001960"
     CDS             2590..3309
                     /gene="trmD"
                     /locus_tag="VYN12_001960"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1416262.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            3321..3659
                     /locus_tag="VYN12_001961"
     CDS             3321..3659
                     /locus_tag="VYN12_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416263.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(3690..4010)
                     /locus_tag="VYN12_001962"
     CDS             complement(3690..4010)
                     /locus_tag="VYN12_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416264.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            4108..4323
                     /locus_tag="VYN12_001963"
     CDS             4108..4323
                     /locus_tag="VYN12_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1416265.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(4392..4472)
                     /locus_tag="VYN12_001964"
                     /pseudo
     CDS             complement(4392..4472)
                     /locus_tag="VYN12_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4528..5064)
                     /locus_tag="VYN12_001965"
     CDS             complement(4528..5064)
                     /locus_tag="VYN12_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1416266.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT         1741 a          898 c         1105 g         1489 t
ORIGIN      
        1 tttcctattc taacaaattt ctaaatactt taagaaattt atagtctgtc aagttttttt
       61 cttgacacat gccagaaatc tgctataata gaacatgtgc tagatagctc agctatttca
      121 ccgaaataaa aaattaaaga aatgagactt taaaaatggc agttaaaatc cgtttgactc
      181 gtatgggttc taagaaaaaa cctttctacc gtatcaacgt agcagattca cgttcaccac
      241 gtgacggacg tttcatcgaa acagttggaa cttacaaccc acttgttgct gaaaaccaag
      301 taactttgaa agaagaccgc gttcttgcat ggttggctaa tggagctcaa ccttcagaca
      361 cagtacgtaa catcctttca aaagaaggcg tattgaaaaa attccacgat tctaaatttt
      421 caaaataagt ttaaagtagg ttgacagatg gatacgattg aaaatctcat tattgcgatt
      481 gtgaaaccct taatttcaca accagatgcc ttaactatca agattgagga tacaccagaa
      541 tttttggaat atcatttgaa tcttgatcaa agcgatgtgg gtcgtgtaat cggtcgtaag
      601 ggtcgcacta tttctgcgat aagaacgatt gtctactctg tcccaactga atacaaaaaa
      661 gtaagaatcg ttattgacga aaaataagaa gggcgggacg gatgtctcgc ttttttgtgt
      721 ggaatagaag atatagtaaa atgaaataat aacaggacaa atcgatcagg acagtcaaat
      781 cgatttctaa caatgtttta gaagtaaagg tgtactattc tagtttcaat atactataaa
      841 agattgaacg tttaggcaat tccaagacta cttactcgaa cattaacagc agtctcggac
      901 tgatgaaggt ctctttatga agttagtgga gaagtcggag aagtagccga ggttttgaat
      961 aggcgctctg gtcgaaaaga agggatagga ttcgaacgag gaacttgcca gagaactggc
     1021 tgatatcatt tactacaccg tcgcaatcgt agctattaat catattgacc ttaccaagac
     1081 tgtctttgag aaagacaaaa ccgcagccgt taattaccaa cataaacatg atttggaagg
     1141 atttttgaag ggaaagtaga gatgttgtcc ccttcctcca acttgagaaa atccttggaa
     1201 cgtgataaaa taaaagataa ggatttttaa taattcatta tatagaatga gtggatttct
     1261 ttatgaagag gtttgaagta tctacagaaa ttggtagcct ctctgttact tatcaaaagc
     1321 aaaagaaagt gctagtttgt ctaaacggag caggtttgct accaagttat gaaaattttt
     1381 cacttatact tgaaaaacct cctcctacaa ttggttattt gacaattgat tttccgaaca
     1441 caggtaggag tccgattcat gaccaagctg gaaaaaatct agataatctt gcagatgcgg
     1501 tttatgaagt acttgaagaa ttaggaattt ctgaatatat actttgtgca catagttgga
     1561 gtggaatttt agcttgcaaa ttactcgaga aaccaattaa gcgtcagact ttagtagcaa
     1621 ttgaaccgac aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct tatccagaaa
     1681 tggaagagca gatgaggctg attgacgagt gtggtcctga actttatttt aagaacttaa
     1741 ctcaagcaac atttagtcct gaaacgaata aaaaaatctg ggaattaatg caagaaaaag
     1801 gcttagagtt ggaaaatcaa gatccagaat ttcagatatc tggagagatt actgaggaag
     1861 attttgagaa tttgtcgata gaatctcatg tccctgtatt tattttttgt cagacttata
     1921 gagaaaaaga gtacagagaa tcagaatatt ggacttccaa tactaaactc attttaggaa
     1981 ggaatcacca ttatttacaa tggtcagaat aggaaaaaat tgcggctatt attcgagaat
     2041 tgtcagaata agatggaaaa aaggagatta caggagacaa gatgaactac tttaatgttg
     2101 ggaaaatcgt taatacgcag ggattacagg gtgagatgcg agtcttgtct gtgacggatt
     2161 ttgcagaaga acggtttaaa aaaggagctg agctggcttt gtttgatgaa aaagatcagt
     2221 ttgtccaaac agtgaccatc gctagccacc gtaaacagaa gaactttgac attattaaat
     2281 tcaaagatat gtaccatatc aatactatcg aaaagtacaa gggatacagt ctcaaggtcg
     2341 ctgaggaaga tttgaatgac ctagacgatg gtgaatttta ctatcacgag attatcggtt
     2401 tggaagtcta tgagggtgat agcttggttg gaaccatcaa ggaaatcctg caaccaggtg
     2461 ctaatgatgt ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta ccttatatcc
     2521 caccagtggt tctcaatgtt gatattccaa ataaacgggt cgatgtggaa atcttagaag
     2581 ggttagacga tgaagattga tattttaacc ctctttccag agatgttttc tccactggag
     2641 cactcaatcg ttggaaaggc tcgagaaaaa gggctcttgg atatccagta tcataatttt
     2701 cgagaaaatg ctgaaaaggc ccgtcatgta gatgatgagc cctacggagg cggtcagggc
     2761 atgttgctca gagcacaacc tattttcgat tcctttgatg ctattgaaaa gaaaaatccg
     2821 cgcgttattc tcctcgatcc tgctggaaag cagtttgatc aggcttatgc tgaagatttg
     2881 gctcaagagg aagagctaat ctttatctgt gggcactatg agggttatga tgagcgcatt
     2941 aagaccttgg taacagatga gatttcccta ggcgactatg tcctcactgg tggagaattg
     3001 gcagctatga ccatgattga tgctacagtt cgcctgattc cagaagtgat tggcaaggag
     3061 tctagccacc aagatgatag tttttcttca ggtcttttag aatatcctca gtacacacgt
     3121 ccctatgatt atcgaggcat ggtcgtgcca gatgtattga tgagtggcca ccatgaaaag
     3181 attcgtcagt ggcgattgta cgagagttta aagaaaacct acgagcgcag accggattta
     3241 cttgaacatt atcaactgac agtagaagaa gaaaaaatgc tggcagaaat caaagaaaac
     3301 aaagaataaa ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt gctgaattta
     3361 atccagataa gatttaccaa gccatcttga aggcagccca aactgtttat gttttgacag
     3421 atgatttgcg tcaaaatctt gctcaagtca ctaagaaggt agttttggat ttacaagaag
     3481 ccaaggtgga acgtgcgact atcagtatga ttcaatctat ggttgaacat cgtttattgg
     3541 gcgcaggtta cattaccatt gcagaacact acatttccta tcgtttacaa cgtgacttgg
     3601 aaagaagtgg ttatggagat catattgcag ttcatttaca ttttgaacaa attcgctaag
     3661 aaaaaagagt gggatgaagc aactacatct cactctttct taaatctatt tttttgggct
     3721 gtttggacag ttgaggggac aaatcgcagg cgttgaatat cgcttatacg gataatccgg
     3781 ctcacatttt tggcaaaatt tttcacgata atttgctggc cttgctgatc atatttgatg
     3841 atatcacctg taaaacttgt ctcagacaag ataaggtgaa cagcggtttg tttctggata
     3901 gcctcttcaa tagtggctgt aagggagttg gtttcagtct ggtcaggttg gtcatgtcca
     3961 tttaaaaaat catgtatttt atctagaact tgctggaatt tatgtctcat attggcctcc
     4021 cttcttttat atcaatatta tataaaattt tcctaaaatc tacaagattt tacgaataaa
     4081 ctaatgaaac taaaaaagga gaagaaaatg gcagaattta catttgaaat cgaagagcac
     4141 ttgttgactc tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg tgtgagcttt
     4201 aatggtgccc ctgcaaagtt tgatattcgt gcttggagtc cagaccatac taaaatgggc
     4261 aaagggatta ctctctcaaa tgaagaattt caaacgatgg tggatgcctt taaaggcaac
     4321 taatactctt cgaaaatctc ttcaaaccgc atcagctttg ccttgccgta tgtatggtta
     4381 ctgacttcgt cagtttcatc cacaacctca aaacagtgtt ttgagcagcc tgcggctagc
     4441 ttcctagttt gctctttgat tttcattgag tataagtttt caaaataaaa aaaaggatat
     4501 tgagtcatga taactcggta tcctttttta gttagtaaag taagcctgat ttttaaggcg
     4561 ttgaagtagg ggacggctaa taaaactaat agccagaagt ttgccaaggt ctggaatgat
     4621 aaagggaaga acccccacaa caagagcttt ttcaaatgcc attccagcta ggaaatgcaa
     4681 gctgagaatc ccgccgacaa agacaagggc atcacccaag aggtttgcaa gaaaaatctt
     4741 aacaacacca ctcttgctgt tggttagaga ggaagtaagt ccagagtaaa cgagataaaa
     4801 ccaaagatag cctgcagtag ggccaactaa agcctgaaaa ccagctccac ctcctgcaaa
     4861 gacaggaaga ccgatagcac ctagaagaag atagagtcca gcagaaagta cagcctctct
     4921 cggtctaaag acagtagcaa tcaagccgat tgcaaagttt tgcagagtga agggaacagg
     4981 tccaattgga agactgattt gtgccaaaac agcaatgaga gcagccccaa tagcagggat
     5041 agcataaacg tgagcttttt tcaaaatagt taacctcttt tctaatgtat agtaactatt
     5101 atactcatat aggagtcgat gtcaaccatt ttttaaaaac aaggtaacaa aaactgtaac
     5161 agccgatttt cgtgactagt caagttggat aatttttttg ttgattcgaa aattgtctgt
     5221 atagataatc cta
//
LOCUS       DAVLTG010000085         5158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLTG010000085 DAVLTG010000000
VERSION     DAVLTG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.086"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(277..1005)
                     /locus_tag="VYN12_001966"
     CDS             complement(277..1005)
                     /locus_tag="VYN12_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1416267.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1163..2572
                     /locus_tag="VYN12_001967"
     CDS             1163..2572
                     /locus_tag="VYN12_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1416268.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2590..3885
                     /locus_tag="VYN12_001968"
     CDS             2590..3885
                     /locus_tag="VYN12_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1416269.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3890..4198
                     /locus_tag="VYN12_001969"
     CDS             3890..4198
                     /locus_tag="VYN12_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1416270.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4195..4503
                     /locus_tag="VYN12_001970"
     CDS             4195..4503
                     /locus_tag="VYN12_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1416271.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1744 a          866 c          935 g         1613 t
ORIGIN      
        1 aaaagactca aaaacttctc gtcagtgtaa gaatatttga aacactattt aaaactaaat
       61 aactataaga agtagatcag gtgaacaatt tcagtaccta ctctataagc tatacgaaga
      121 tatttttcaa catgatggat aaaacgatca ctcttttaaa gccatcttat ttagaaaaga
      181 gaaaccattt aagcatagat gggaccttct tgccctgttt taaatttttc ttaaactaga
      241 gtctgtaaaa gattggcttc attttcacat tttctcctag gaggaatgtc gtaatgcaaa
      301 agaattaaat tcaaataaat catagcgatg acgactaatc gagtactcaa acggagttcc
      361 gttatccaaa taagccactt gttctacttc aaataccggt tccgttggaa ggagctgcaa
      421 gtaatgttgc tcattttctg aactagaaga agctcgtaag atttttgtag cactggcaat
      481 atgcaatcct aactttcctt caatgtaatt gtaaatcgat ttttgtaaaa tatcttcagt
      541 aatacctgga ataacatcgg tactcatata agtttgttcc agaacataag gtttaccgtc
      601 aataatacgc aggcggtaaa tattataaac tggactctgc aaagcgacct gtagtttttc
      661 tgctaaaaat tcatttgcaa attctaattt gaagtgaata atcctcgagt caattgtaga
      721 atgagcatct tcagatattt ttgtcagtcc ccggatatct ctttctggaa cgattaattt
      781 tctttttgag ctgccacgag agagaacaaa ggttccctgc ccacgttttc taaaaattaa
      841 gccctcagaa actaacaagt ctaaagcttt tttgatcgtc attcgactac aggcaaactg
      901 tttagctaat gtcatttcat caggtaattg ttcgttcatg gtatatttat tacaaagaat
      961 cttttcacga atctcattgt aaataaataa atattttgta ctcatttaat ctggttctct
     1021 ctataatatt ctaatagtag tataacaaag ttcaagaaat gaggcaaaca caagatatgt
     1081 atcaacaatt tttaaaaatg tctagacaaa ttttaaaatt atgctatact ttatgtatag
     1141 aataatagaa aggaggttga gcatgaaaaa aaagttagta tttcctaatc tgttttggtg
     1201 gggagcagct tctagcggac ctcagacaga aggtcaatat ggaaaagtac atgaaaatgt
     1261 gatggactac tggttcaaaa cgcatccaga agattttttc gataatgtcg gacctcttgt
     1321 agccagtaac ttttttcata cttacaccga agatttccac ttgatgaagg aaattggagt
     1381 taattctttc cgcacttcca tccaatggag tcgactcatc aagaatttag agacaggtga
     1441 gcctgatcca aaaggtattg ctttctacaa tgccatcatt gaagaagcta aaaagaacca
     1501 gatggatctt gtgatgaatt tacatcattt tgatttacca gtggaacttc ttcaaaaata
     1561 cggtggttgg gaaagcaaac atgtagtgga gttattcgtg aagtttgcca agactgcttt
     1621 cacatgcttt ggagataagg ttcattactg gacaactttc aatgagccaa tggtcattcc
     1681 agaagcagga tacttatatg ctttccatta tccaaatcta aaaggaaagg gaaaagaggc
     1741 cgtacaagtc atctataatc taaaccttgc tagtgcaaaa gtgattcaac tatatcgctc
     1801 attagaactt gatggaaaga ttgggattat tttaaacttg acacctgctt atccaagaag
     1861 taattctcca gaagacttag aagcaagtcg atttacagat gacttcttta acaaagtctt
     1921 cttgaatcca gctgttaaag gaactttccc agaaagattg gtaaaacagc tagagagaga
     1981 tggcgtgtta tggagtcata ccgaaaaaga gcttcaactg atgaaatcaa atacggttga
     2041 ttttcttgga gtaaactact accatccaaa acgtgttcaa gcacaagcaa atcctgagga
     2101 atatcagacg ccctggatgc cagaccaata cttcaaagag tatgaatggc cggagcgtcg
     2161 catgaatcca tatcgtggtt gggaaatttt tccgaaatcc atttatgata ttgctatgat
     2221 tgtgaaggaa gaatatggta atatcccatg gtttatcagt gaaaacggaa tgggtgttga
     2281 aaacgaagca cggtttatcg atgaaaatgg agttatcgat gacgtgtatc gtattgaatt
     2341 ttatgaagaa catttaagat ggctacataa agccattgaa gagggaagtc actgttttgg
     2401 ataccacgct tggaccgcat ttgattgctg gtcttggaat aatgcatata agaatcgtta
     2461 cggatttatc tccgttgatt tagaaacgca aaagagaacc atcaagagct caggaagatg
     2521 gtatcgcaaa gtaagtgaca ataacggttt tgaagtagaa attgaggagt aaagagagga
     2581 gatattcata tgaaaaactc aaaatttata gaccaatttg ccacctttgc tggtaaacta
     2641 gggaaccaaa ttcatttaaa aaccctaaga gatgcattcg taacagtaat gccattatat
     2701 attttggcag gtttaatcgt tcttttgaac aacacggtat ttaagtggat tttccaaggg
     2761 gatacattaa caagattcca atattgggga ataacaattg caaacggtac tttaagtatt
     2821 tcaggtatga ttattgctgt aatggttggt tatttcttag ctaaaaacag agatttcgaa
     2881 aacccgttag cagcatcaat gctatcatta gtttctttaa ttgtgatgat gccaaataca
     2941 gtttctgtag ttcctgacgg agcaaaagat gctgtaaaca tttcaggtgt tctttcattc
     3001 aacaacacag gtacaggcgc aatgttcgcc ggggttatcg tagcgattat tgcaacagaa
     3061 ttattcattg aattatcaaa tgttaaagct ttacaaatga accttggtga aaatattcca
     3121 ccagctgtta atagatcatt tagcgtatta cttccagtca tgaccgtcat ctccttattt
     3181 ggggttgttt cagcattatt attcaatata actggaatga acttaatctc aatcattaca
     3241 atctttattc aagaaccaat tcgtcatatt ggtacaagct taatcggggt cattattatt
     3301 tactctttag gaaatatgtt atggctattt ggtattcacc aagcagttat ttacagtgcc
     3361 atcctagaac cattactatt aattaacatt actgaaaaca tcactgcagc aaataatgga
     3421 caagccattc cacacatcat caacctatca caaatacaaa cattcgcttt aatgggtggt
     3481 agtggatcta cattatgttt attaatagca acattcttag tgagtcgcaa tgctgtctct
     3541 aaaaacgtgg ctaaattatc ttttggacct ggtatcttca atatcaatga accagtatta
     3601 ttcggttacc caatcgttta taacatttca ttagctattc catttatcac agttccagtc
     3661 cttggtattt taatcagcta cttagcaaca gttacaggat tcatgagtcc tgcatttata
     3721 caagttcctt ggactacacc agtattctta aatgcatggt tagcaacagc aggggacgtg
     3781 agagcagttc tagttcaatt catcatcttt gcacttggag ttcttctata cattccattt
     3841 atcaaagtta atgacaaagt tgttgaacaa gaaatggaag gttaagatta tgaaacaaat
     3901 tttattagta tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag
     3961 tgcgactgaa cgtgggattg aaatctctat ccaagcaaaa tcaatgacag aagctaaaaa
     4021 gaatatccat gaagcagatg tcattctaat tgggccacaa attcgttatg agttacttgc
     4081 tgtgaaagaa attgcaggaa atatccctgt agataccatt gatatgcggg attacggaat
     4141 gatgaatgga gcaaaagttc tggaacaagc acttgcatgg ataggagaaa taagatgaca
     4201 gaagaaatgg aatatatctg ttttcagctc attgccaata gtggagcagc caaatcatcc
     4261 tttattgaag ccatccaact agctaaggca ggaaatttaa aagaagcgaa aattaaagtt
     4321 gaagaagcgg aagactcctt agtagaagcg cacaagattc actctaatct catacaaaaa
     4381 gaagctactg gagaaaaaat aggattctcc ttgctattta tgcatgcaga agaccaaatg
     4441 gcttcaacag agattattca gttgctatct aaagaattca tcgatctcta tcaaaataaa
     4501 taggaacact gtcattccca tctgtcttta ttaatgacga ctacattgta ggaacctcca
     4561 aaagttggac aaaatgattg aaaggattgg atcctgcatt acacaagatc caatcctttt
     4621 cttttactct agtttttata atatgttgaa tctagaatag tccactgtag tttctaaaaa
     4681 attgctggaa atggatgtta agctccaatt tatttgttta tatcttattt cagtttacta
     4741 tactagctta ttattctagt gaaaaattga atgagccact atttatttaa tatgtatgat
     4801 gagggaatga ctcaaaaact tcttgtcgat ataagaatat ctgagatagt attttaaaac
     4861 gaaaggacta taaaagctca tttccttcgc acttatttta tagagatcta tcattatact
     4921 ctttagaaat caaaaagcaa cacaccttgt catcgtttta tcgtaaatct gttaatgagg
     4981 gggctagtct tatctgcaat ctcaaatcag tgttttgagc tgaatggcac tcgttttcta
     5041 gtttgctctt tgattttaat tgggccttag taaatactac tcttaaatta aactatagtg
     5101 aattgaaata agatgtgaac aactctatca gaaaagtaaa attaatttct ataaatgt
//
LOCUS       DAVLTG010000086         4570 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLTG010000086 DAVLTG010000000
VERSION     DAVLTG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.087"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(422..973)
                     /locus_tag="VYN12_001971"
     CDS             complement(422..973)
                     /locus_tag="VYN12_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1416272.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1323..2147)
                     /gene="nadE"
                     /locus_tag="VYN12_001972"
     CDS             complement(1323..2147)
                     /gene="nadE"
                     /locus_tag="VYN12_001972"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1416273.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2144..3604)
                     /locus_tag="VYN12_001973"
     CDS             complement(2144..3604)
                     /locus_tag="VYN12_001973"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1416274.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3720..4208)
                     /locus_tag="VYN12_001974"
     CDS             complement(3720..4208)
                     /locus_tag="VYN12_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416275.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4198..4407)
                     /locus_tag="VYN12_001975"
     CDS             complement(4198..4407)
                     /locus_tag="VYN12_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1416276.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1322 a         1057 c          836 g         1355 t
ORIGIN      
        1 gataattttc actcatcttt catcattcct tatacaacta tgcagtataa atagaatagt
       61 tttctcatca gaatgagact attttaatat tagataattt gatagaaaaa acatgaataa
      121 aattggttga atttaattcc ctaactcgat agaggattct attttaaatt taacaacagc
      181 taggattaca ctataaaaag tacattacca cctgttcggc tggagaatct agtcgattag
      241 ctccctctta gttacaagct tcaagcgatt ttttaactaa cactaaacca gattaaagaa
      301 ggaactagaa catctgtctt gtactaatca atatgctatt ttaaagtttc aaataaactt
      361 ggaatgctaa ttattatatt tacaataaat agttgacttc gatagaaaca gaaaatagaa
      421 ttcaacattc ttccctactt ataccataat aaataagatc cgcaagatag ccttttctct
      481 ctacaccatt aacaatggtt tgtagatagg acattccagc cttttccatg acacgacctg
      541 aagctgggtt gagactggca taacgtgctc tgaccttttg aaaacctgct tgagtaaaac
      601 aaaagtccaa gatagctttc aaagtctctg tcatcatacc atttccccag taagccttgc
      661 ctaacacata gccaatttca cagcttaaat cagcctcgtc tatcttaaca atgctgatat
      721 ctcctattac ttgctctggg ttttctttta gacaaatggc ccatttataa tagttgagat
      781 tagtatagga agcaacccaa ttgcaaatcg agtttcgagt gatttcgaca tcaggatggg
      841 gatcccaggt aacataggtc agattctcag cggatgaagc ccaattttga aacatggctt
      901 ctgcatcact ctccacaaat cttcttaaaa tcaaacgttc tgtctgtaat atttgcgtac
      961 cgatagattt catgatgcta cctcacttcc ttatttctat actcgtagta aaaaggctca
     1021 actcagtaac agctagaaaa cgagtttgtc ttctaatttc ttgacgcagt tgctgcctgg
     1081 tttgaaatgc gctctagcaa gctttttcaa acctagtcat cgttgcaggg gtaagacgat
     1141 gaaatcgaac tcttcgagtt actgaatctg cctcattttc ttatttctaa actcggggtt
     1201 caagatcccc cagaccttct ctcactttct tatttcaaga tgagaggctg aaaacctcca
     1261 gtggaggttt ttcttgcttt ttaatttcag ggcaagaagc taaaaaggtc ccccggacct
     1321 ttttactccc aaaagtcatc aaatacggtg atgggtaagt ggcgtttgtg ttggcctttg
     1381 tgccaccagt tttcaatggt cgcttgagct tctgggctga ttgttttgcc ttctaggtag
     1441 tcgtcaatct ctgcgtaggt gactccaagt gcgacttcgt cagctaggcc tggtttatct
     1501 tcttctaggt ctgccgttgg gattttttca taaagggctg gctctgcgcc aagtttctgc
     1561 aagagctgtt ttccttggcg tttattgagg cggtaaagag ggagaatatc cgcaccgccg
     1621 tcaccaaact tggtaaagaa acctgtgata ttttccgcgg cgtggtctgt tccaatgacc
     1681 gctccgctat gggaaccagc aagggcatac tgagcaatca tacggcaacg tgccttgata
     1741 ttccccttgt tgaagtctga aacaggacta cctgtcgctt caactgcagc tgtcatggca
     1801 tcagctgatt ccttgatatt cacaaccaag ctgacatctg gctggatgaa ggctagggct
     1861 ttttgagcat ctgcttcatc agcttgcact ccgtatggca ggcggacagc gataaatttg
     1921 tagctatcgt ctcccgtttc agctcgcagt tcttccatag ctaattgcgc caaacgtcct
     1981 gccaaggttg agtcttgtcc cccagaaatc cctagtacaa aggtttttag gaagggatgt
     2041 tttttcagat atctttttaa gaaatcaata gaacgacgga tttcttcctg ggcatcaatc
     2101 actggtttga cacccagctc ttggataatc gtttcttgca aactcattct tcttctcctt
     2161 caccaagggc ttccttgcgc atcttatcaa tcaagtccat cttatcttgc catacatcac
     2221 gcgccaaatc cactggatag tgctgcggat tgagcacacg cttatactca tcccacaact
     2281 tgtcaaattc cttacgggca taatcctgaa tgtcagtcaa actaggcaag ttgtaaacta
     2341 atattccttc tttgaagata tccaccaaga gaggaacggc atcaaaatta cgaaccgtct
     2401 tcttgatgta tgtataggtc ggatggaaca tcttgatttc tgtcatgtcg ctaatatcca
     2461 caccatcata agtgatatag tcgccttctg acttgccttt ttcacgactg gtaatgcgcc
     2521 acacctgctt cttacctggc gtagaaactt tttcagcatt attagacagc ttaatcgtat
     2581 tgcgcatctg accagtttca tcttcgattg caacaatctt gtaaaccgcc ccaagagccg
     2641 gctggtcata ggctgtaatc agcttggtac ccacacccca gacatcaatc ttggcctttt
     2701 gcatcttgag gttaaggatg gtattttcat ctagatcatt agaagcataa atcttagcct
     2761 ctgtaaatcc agcctcatcc agttgctgac ggactttctt agaaatgtag gcaatatccc
     2821 cagagtcaat ccgcacaccc ataaagttaa tctgatcacc cagctcacgc gccacctgaa
     2881 tggcagctgg tacaccgatg cgaagggtgt cataggtatc cacaagaaag acacaatttt
     2941 tgtgggtcgc agcgtaagcc ttgaaagctt catagtcatt gccataaacc tgtaccaagg
     3001 catgggcatg ggttcccaaa acaggaatgt caaagagctt acccgcacgc acgttgctag
     3061 ttccattggc gccaccaatc acagctgcgc gtgttcccca gatggccgca tccatttctt
     3121 gagcccgacg tgtcccaaac tccatcaagg gttcatcttc gataaccgaa cgaatacgag
     3181 ctgccttcgt cgccaccaag gtctggtagt tgacgatgtt caaaagagcc gtttcgacca
     3241 actgacattg ggctagaggt ccttccacct gcacaatcgg ttcattagca aaaaccaaat
     3301 ccccttcttg ggcagaacga acggtcaact ccaacttgaa attgcgaagg taatccaaga
     3361 acgccccatg ataaccaagc gactccaaat aggctatatc actatctgaa aaacgcaagt
     3421 cttcaagata gttcacaatt ctttccaaac ctgcaaaaac cgcatagccg ttcttaaaag
     3481 gctgttggcg gaaatacacc tcaaagaccg ccttcttatt gtgaatccct tggtcaaagt
     3541 aaacctgcat catgttgatc tggtacaagt ccgtgtgcaa tgtcaaacta tcatctggat
     3601 acatactttt cctacttcct tagctagaaa cccatgaaaa ttttcaagaa ctttcatgta
     3661 ttccaataaa ttagtactat tatatcacat tttagctgga ttgagaaaag agtaacaagc
     3721 tattctccac tctccaattc atccatatct tgttcaaatt ttttctgagc ccattcgcca
     3781 tagctcttaa gaccaagatt gccaataaag atccacggaa ggtaaatgat ataagtaatg
     3841 acccaagcag acaggtattt aaaattcaaa ggattgtgct gataaatttc tatgttgaat
     3901 tgataattct gcaacatcaa aagagccgta atagccaagg ttaggaaaaa acaacccaaa
     3961 atcgtaaaat gaaaacgact atagtaggtc actcccagat aacgggcacg attgaaaaag
     4021 taaaatgtcc ctatgatgat aacgattagc agcatattag aattaaaaag gcttggtgct
     4081 aatactgaaa tgatataaga taggagcgac aaagcgatgc agatatagaa actttcagag
     4141 cccgctttat tgaacagttg ttcttctctt tcgtctagta attgataata ataaaatcta
     4201 tttttcatct tcttcctccc aaaatagttg gtctagggtt ttccctaaac atctgcaaat
     4261 ggactggcag agcgagagac tgggattgta tttccccgct tctatcaaac caatagtctg
     4321 gcgcgtcacc ccgacagcct ctgccagttg accttgtgtt aaatcacgct ctacccgagc
     4381 taattttaat tttaaatttt tagccacctt cgtcctcctt atagttttaa tactcatcta
     4441 ctcttaaaaa atccaaaacc aacacaagct atcagctatt tattataacc ccattaattt
     4501 gcactccagt attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc
     4561 tagtttactc
//
LOCUS       DAVLTG010000087         4403 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLTG010000087 DAVLTG010000000
VERSION     DAVLTG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.088"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            128..202
                     /locus_tag="VYN12_001976"
                     /pseudo
     CDS             128..202
                     /locus_tag="VYN12_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(664..825)
                     /locus_tag="VYN12_001977"
     CDS             complement(664..825)
                     /locus_tag="VYN12_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1416277.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
     gene            complement(810..1028)
                     /locus_tag="VYN12_001978"
     CDS             complement(810..1028)
                     /locus_tag="VYN12_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1416278.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1126..1911)
                     /locus_tag="VYN12_001979"
     CDS             complement(1126..1911)
                     /locus_tag="VYN12_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1416279.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1913..2731)
                     /locus_tag="VYN12_001980"
     CDS             complement(1913..2731)
                     /locus_tag="VYN12_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1416280.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2733..3725)
                     /locus_tag="VYN12_001981"
     CDS             complement(2733..3725)
                     /locus_tag="VYN12_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1416281.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1484 a          936 c          755 g         1228 t
ORIGIN      
        1 gtacatttat atataattgt tatctctcca taaaaacagt atatcattta aaaaaattta
       61 attcaagaaa aattaacatg cattaattta ttttttagca cacgttaaaa aataagatta
      121 gtactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg
      181 ttttgaggtt gtagatggaa ctgacgtagt cagctcaaaa cactgttttg aggttgtgga
      241 tagaactgac gaagtcagta accatacgca cggcaaggcg acgttgacgt ggtttgaaga
      301 gattttctat gagtataagt ccaaaacttt cgttaaccgg gatacattat aagcacattc
      361 ataccatcaa aaatagtagc aataaacttg aacaactacc agaaacacga aaacaggcat
      421 aattgatgaa atatcagcgc tattaaacaa tataaataac cgctaagaat aaggcttaac
      481 ggttatcttc tacctatcta ttttttcaac tcctcagtcg tttatctacc tataacctag
      541 gctttacgag tgccttgctc taccaactga gctaaatcgg cgattacact tacagtatgg
      601 cactctgaga atagatgtca agtaatatta ttcaagcttt ttaatcaaaa tctgacaagg
      661 attttacgga ttccatagct gagaaaaaat ctctaacttt ttaaagccaa gacctcgata
      721 aaagtcattt gttcgatcat aatctttatt agaaccttct gccactgttt tgacctgcag
      781 ataaccaact tttttacgag cttcactctc taaagtagca agcaattggc tcccaatttt
      841 tctaccttga taagcttttt tacgccgaga caatcaatct ctgcacaatc ttcactcgaa
      901 taggataacc ttacaaatcc agtcaaatca ctctcctgat aggcggtcca aacttgcagt
      961 gtcgtggttc cttctatata ggcttgtgtg ctttctggga ttccaaacca ttctggcaaa
     1021 tccttcaaaa cctcaacgac aactgccttt tttgattttc atccttgact tcttcaatta
     1081 caaacatcat aagttccttt cttgatttta gtcttacttt agcttttacg aacccgcact
     1141 ttcgtaggaa tctaagccct tatcccaaag tttaagggaa ataacaaaga aaaccagaga
     1201 aatcaacatc aaacctccta cgttaaagaa cacatccttt tcctgtaaga aatagctagc
     1261 tggatagtag gctgtaaagg cgaaaggcac gataaagcta atcaaccaac gaagaagaga
     1321 attgtaaata gaaatcggat acttagcaaa gtcattgaac atatagaaga tgtaaatcat
     1381 ggcgcctgac tgcttagtcc aaaaggcgat actggctgtt gcgattttaa gagaagtata
     1441 aatcaaggtc gcaaaaggaa tacaaactag gaaaagcagg aattttggaa gagtccaaac
     1501 aatgctggtc actgttgttc ccaataaaat accaccgact aagagttcac ccaaggcatc
     1561 aatctgaaag gtttcaacta ggatgtgaaa gagaggattg atgggacgag tcagatactt
     1621 gtcaaactct ccttttcgga ctaggcgttg ccctagtgcc cagagattgt caaaaaagag
     1681 atggtccatt cccttgggaa tcaaggaaaa tccataaatg aaagctatct cttgaaaggt
     1741 ccagccttct aggaatggaa tatgttgaaa gatgacattg agaaacaaga gattcaagcc
     1801 ttgagccaga aagactccca agacaccaac cacaaaatcc accttatatt ccatgatttg
     1861 tttgatgtat tgtctgataa aaatcagatg cattcgttga tattttttca tactaacctc
     1921 cttgaatggt gataaaggac tggacccgtt tccaaattaa ctgagacaat cccaccatca
     1981 ctaagagcca gaagaactgc aaaaggagtg cctgaagaat ctgactggca tcgtattttc
     2041 caacaatgat cataactgga gtataaatca aggacgaaaa aggcaaaaag gagagaatat
     2101 ctgaaacaac ctttggaaag aatgccaagg gaatcaaact ccccgacata aaagccacta
     2161 tggaagtctt aagtaggttg gaaccccaaa gatttttaaa cacaaaggct gaaaatccaa
     2221 agcaaatatt aaagaaaaag ttaatcagat aggcgagcgt taagctaaaa agataaagga
     2281 cagttaatcc tagcacctct acaatacctt gacccgatat gattttcatc aagacaatga
     2341 cacttaaaaa tggaaggcca acgctgataa aaatcaacca cttggaacca agctcggtga
     2401 aaagatagga ggccgcaaaa tgcactggtc gcaacaaacg catgataatg gagccatcct
     2461 tgacctcctc cccaatcata aaggacgaat cggatctagt cagaagattg gtcacaaaac
     2521 tcatgatgat gtagagggtg atatccgcca tactgaagcc ctgaatcaaa gactcttgcg
     2581 aagaatcaaa gacagccttc cagagataaa aggccacaaa agcccccatg acatcgccaa
     2641 tccgatagag aataaagttg actcggtaag taatcaactc ctgaacccct gcattgataa
     2701 agggtttata acgtctccac aatttgatca tcctagagct cctttcggta gaagcgacgg
     2761 ataatatcct caatatccgt atccaccatc ttcaaatcgc ggatttcaaa atcagatagg
     2821 gtttgcttga taatgtcagc tgactggtag cgagaactat caaattcaat gttgaggctg
     2881 tttccttgtc tatcaatggt catatcagac agaccttcat agtgagagac gagatgactt
     2941 tgacctggta gcagttcaaa agagagagtc ttcatcttac caaaggtctc cttgagttgg
     3001 ctcaccgttc catcaaaaat cttttgcccc ttgtcaatca tgaaaatccg atcacaaagt
     3061 tgctcaatat cactcaaatc gtgagtggtc aaaagaatgg tagtttcttc ctcttgattg
     3121 atctgagtaa ttgcccgacg aatattatcc ttaaccgaaa cgtccaaacc aatggtcggc
     3181 tcatctaaaa aaagaacctt gggattgtgg agcaaggagg ccgcaatatc cgctcgcatc
     3241 cgttgtccca gtgaaagagt ccgcacggga tccttgataa agtccttcaa atccaagact
     3301 tcattcaaaa agtccatacg cttatgaaag agcgagtttg gcacatcata aatctctttt
     3361 aagacagtgt aggtctcttg cagagccaaa tcccaccata gctgggtgcg ttgtccaaag
     3421 actacgccaa tatctttgac ataatcttgc cgattgtcct ggggaatctt gccgttaatc
     3481 cgacaaaaac cagatgttgg tttcaaaatt cctgtcagca ttttaatggt tgtcgacttc
     3541 ccagcaccat ttgccccgat aaatcctaaa atctgccctt ttggaacctc aaaggtcaaa
     3601 tccttgaccg cttcaaaggt ctgcttttca ggatgaataa aggagcgcaa agcccccttc
     3661 aagcccggtt ccttaacaat cttcacaaaa tgtttctgaa gatgttccac ttctatcatt
     3721 gccatatcta tctccctatc gtaaggaata gcaacattgt gtttttaact acaaatattc
     3781 taaatcctta ctttctacac cttctacatt ttattactac agaaggcttt ataccaacct
     3841 attatagtcc aataaaaaac gaaatgcaag cgtttgccta tagattgtga aattaggatt
     3901 tctctcatga aataatactt ttaatcaaaa attctgttta atagtttaaa ttaccaacct
     3961 actcatcttc tcaccagagg gcggtattaa ctttgatcat aaaatcggat actccctcta
     4021 tccagaaaat atgctcagaa tgattgtctc taaacaatac ctgctctttt acctcattca
     4081 tgaaaaagaa gtccataccc tgagaattat caactcacgc accgactacc taaaccaact
     4141 cgaccacctc tttcgtacat gtaggaaact attttcctca caaataatct cattataaaa
     4201 tccaataaat ttttttagct cacttgaata ttttctttgt atcgttttat cagcttcaat
     4261 ctgatctaga cttgttacct tggaacgact tgaaataacc tttgtaaaat aacacttaag
     4321 gctttcatca tctcgtataa atttttcaat agtgatataa aaagctttca tattctgttt
     4381 gtaatcagat attaattgat taa
//
LOCUS       DAVLTG010000088         4093 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLTG010000088 DAVLTG010000000
VERSION     DAVLTG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.089"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..693
                     /gene="phtD"
                     /locus_tag="VYN12_001982"
     CDS             <1..693
                     /gene="phtD"
                     /locus_tag="VYN12_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1416282.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKP
                     EEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQ
                     VEHSVINAKIADAEALLEKVTDPSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLL
                     ALLKKSQPAPIP"
     gene            903..4022
                     /gene="phtE"
                     /locus_tag="VYN12_001983"
     CDS             903..4022
                     /gene="phtE"
                     /locus_tag="VYN12_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1416283.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSISKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1526 a          684 c          799 g         1084 t
ORIGIN      
        1 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
       61 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      121 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      181 gaacgtccgc attcagataa tggttttggt aacgctagcg accatgttca aagaaacaaa
      241 aatggtcaag ctgataccaa tcaaacggaa aaaccaaacg aggagaaacc tcagacagaa
      301 aaacctgagg aagataagga acatgatgaa gtaagtgagc caactcaccc tgaatctgat
      361 gaaaaagaga atcacgctgg tttaaatcct tcagcagata atctttataa accaagcact
      421 gatacggaag agacagagga agaagctgaa gatactacag atgaggctga aattcctcaa
      481 gtagagcatt ctgttattaa cgctaagata gcagatgcgg aggccttgct agaaaaagta
      541 acagatccta gtattagaca aaatgctatg gagacattga ctggtctaaa aagtagtctt
      601 cttctcggaa cgaaagataa taacactatt tcagcagaag tagatagtct cttggctttg
      661 ttaaaaaaaa gtcaaccggc tccgataccg tagtaaaatg aatggagcat attttatgga
      721 gaagtaacct ttcgtgttac ttctcttttt tagaaaaacg taacagaaac ttgacaaaag
      781 taattttaaa tagtaaacta tttactggtt aattaaatgg ttaaataacc ggtttagaaa
      841 actatttaat aaagtaaaag aagttgagaa aaaacttcat catttattga aatgagggat
      901 ttatgaaatt tagtaaaaaa tatatagcag ctggatcagc tgttatcgta tccttgagtc
      961 tatgtgccta tgcactaaac cagcatcgtt cgcaggaaaa taaggacaat aatcgtgtct
     1021 cttatgtgga tggcagccag tcaagtcaga aaagtgaaaa cttgacacca gaccaggtta
     1081 gccagaaaga aggaattcag gctgagcaaa ttgtaatcaa aattacagat cagggctatg
     1141 taacgtcaca cggtgaccac tatcattact ataatgggaa agttccttat gatgccctct
     1201 ttagtgaaga actcttgatg aaggatccaa actatcaact taaagacgct gatattgtca
     1261 atgaagtcaa gggtggttat atcatcaagg tcgatggaaa atattatgtc tacctgaaag
     1321 atgcagctca tgctgataat gttcgaacta aagatgaaat caatcgtcaa aaacaagaac
     1381 atgtcaaaga taatgagaag gttaactcta atgttgctgt agcaaggtct cagggacgat
     1441 atacgacaaa tgatggttat gtctttaatc cagctgatat tatcgaagat acgggtaatg
     1501 cttatatcgt tcctcatgga ggtcactatc actacattcc caaaagcgat ttatctgcta
     1561 gtgaattagc agcagctaaa gcacatctgg ctggaaaaaa tatgcaaccg agtcagttaa
     1621 gctattcttc aacagctagt gacaataaca cgcaatctgt agcaaaagga tcaattagca
     1681 agccagcaaa taaatctgaa aatctccaga gtcttttgaa ggaactctat gattcaccta
     1741 gcgcccaacg ttacagtgaa tcagatggcc tggtctttga ccctgctaag attatcagtc
     1801 gtacaccaaa tggagttgcg attccgcatg gcgaccatta ccactttatt ccttacagca
     1861 agctttctgc cttagaagaa aagattgcca gaatggtgcc tatcagtgga actggttcta
     1921 cagtttctac aaatgcaaaa cctaatgaag tagtgtctag tctaggcagt ctttcaagca
     1981 atccttcttc tttaacgaca agtaaggagc tctcttcagc atctgatggt tatattttta
     2041 atccaaaaga tatcgttgaa gaaacggcta cagcttatat tgtaagacat ggtgatcatt
     2101 tccattacat tccaaaatca aatcaaattg ggcaaccgac tcttccaaac aatagtctag
     2161 caacaccttc tccatctctt ccaatcaatc caggaacttc acatgagaaa catgaagaag
     2221 atggatacgg atttgatgct aatcgtatta tcgctgaaga tgaatcaggt tttgtcatga
     2281 gtcacggaga ccacaatcat tatttcttca agaaggactt gacagaagag caaattaagg
     2341 ctgcgcaaaa acatttagag gaagttaaaa ctagtcataa tggattagat tctttgtcat
     2401 ctcatgaaca ggattatcca agtaatgcca aagaaatgaa agatttagat aaaaaaatcg
     2461 aagaaaaaat tgctggcatt atgaaacaat atggtgtcaa acgtgaaagt attgtcgtga
     2521 ataaagaaaa aaatgcgatt atttatccgc atggagatca ccatcatgca gatccgattg
     2581 atgaacataa accggttgga attggtcatt ctcacagtaa ctatgaactg tttaaacccg
     2641 aagaaggagt tgctaaaaaa gaagggaata aagtttatac tggagaagaa ttaacgaatg
     2701 ttgttaattt gttaaaaaat agtacgttta ataatcaaaa ctttactcta gccaatggtc
     2761 aaaaacgcgt ttcttttagt tttccgcctg aattggagaa aaaattaggt atcaatatgc
     2821 tagtaaaatt aataacacca gatggaaaag tattggagaa agtatctggt aaagtatttg
     2881 gagaaggagt agggaatatt gcaaactttg aattagatca accttattta ccaggacaaa
     2941 catttaagta tactatcgct tcaaaagatt atccagaagt aagttatgat ggtacattta
     3001 cagttccaac ctctttagct tacaaaatgg ccagtcaaac gattttctat cctttccatg
     3061 caggggatac ttatttaaga gtgaaccctc aatttgcagt gcctaaagga actgatgctt
     3121 tagtcagagt gtttgatgaa tttcatggaa atgcttattt agaaaataac tataaagttg
     3181 gtgaaatcaa attaccgatt ccgaaattaa accaaggaac aaccagaacg gccggaaata
     3241 aaattcctgt aaccttcatg gcaaatgctt atttggacaa tcaatcgact tatattgtgg
     3301 aagtacctat cttggaaaaa gaaaatcaaa ctgataaacc aagtattcta ccacaattta
     3361 aaaggaataa agcacaagaa aactcaaaac ttgatgaaaa ggtagaagaa ccaaagacta
     3421 gtgagaaggt agaaaaagaa aaactttctg aaactgggaa tagtactagt aattcaacgt
     3481 tagaagaagt tcctacagtg gatcctgtac aagaaaaagt agcaaaattt gctgaaagtt
     3541 atgggatgaa gctagaaaat gtcttgttta atatggacgg aacaattgaa ttatatttac
     3601 catcaggaga agtcattaaa aagaatatgg cagattttac aggagaagca cctcaaggaa
     3661 atggtgaaaa taaaccatct gaaaatggaa aagtatctac tggaacagtt gagaaccaac
     3721 caacagaaaa taaaccagca gattctttac cagaggcacc aaacaaaaaa cctgtaaaac
     3781 cagaaaactc aacggataat ggaatgttga atccagaagg gaatgtgggg agtgacccta
     3841 tgttagatcc agcattagag gaagctccag cagtagatcc tgtacaagaa aaattagaaa
     3901 aatttacagc tagttacgga ttaggcttag atagtgttat attcaatatg gatggaacga
     3961 ttgaattaag attgccaagt ggagaagtga taaaaaagaa tttatctgat ctcatagcgt
     4021 aaggaatagc agtagaaaaa gtctgaatca aaaatgaagt tctctcaaaa gttagaaata
     4081 aaactctgac ttt
//
LOCUS       DAVLTG010000089         4032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLTG010000089 DAVLTG010000000
VERSION     DAVLTG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.090"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            185..637
                     /locus_tag="VYN12_001984"
     CDS             185..637
                     /locus_tag="VYN12_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416284.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYICRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1456..1815
                     /locus_tag="VYN12_001985"
     CDS             1456..1815
                     /locus_tag="VYN12_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416285.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            1825..2190
                     /locus_tag="VYN12_001986"
     CDS             1825..2190
                     /locus_tag="VYN12_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1416286.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQNQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            2177..>4032
                     /locus_tag="VYN12_001987"
     CDS             2177..>4032
                     /locus_tag="VYN12_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1416287.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENA"
BASE COUNT         1460 a          610 c          800 g         1162 t
ORIGIN      
        1 gtgaaaatat tataagtgag aaagatggaa gttatcaaca ttcactgact ataatgaagg
       61 atttcaataa tcaaaaaata gttaactata ttgctcattt caatagttat gacattttga
      121 aaaaaggttc tcacttatca ggtgcatata aacgaaaaat tttttctaaa gaaaatacac
      181 gattttggag tttaatatta actcgaaaga atcttcgcaa caacttgata ttctctataa
      241 agaagttggt gtattaagtt tgggacaaaa agttgtagcc atgcttgatt ttttattagc
      301 atatagtgat tattctaaag acttcagacc attgattatt gatcagcctg aagacaatct
      361 agacaatcgt tatatttgca ggcatttagt tcagcagttt agagatgtga aagctcaacg
      421 tcaaattatt ttagcaacac ataatgctac aattgtaaca aattctatga cagatcaagt
      481 tgttattatg gagtcagatg gagttaacgg atggattgaa tcacagggat atgttagtga
      541 aaaatatata aaaaatcata tcatcaatca attagaggga ggaaaagatt ccttcaagca
      601 taaaatgtct atatatgaga cggctttatc agagtagagt cagaaaaagt aggttagaaa
      661 tttagcctac ttttttcttt gtccgacagg catagtgtgc atctgaggtc caagtcctct
      721 gtggatattt gctgcagatg aaaccaatag cgactcctaa gcctgaatat cgtgaggtag
      781 gggggatagg aaggaattag cgaaatcaag gttctacaaa cagaatcgtg acttgaagcc
      841 atatatagcg gatgaggaac tctaaaatcc aaataggtgt cgtaacctat atacgtaaat
      901 tacgagagta aactaggaaa gatgtacggc ttattccgtg agcgtttagg acgtagtaca
      961 acgaatcatg ggagtcagct gaacacatag tattgaagaa atttctgtaa tggaaatgga
     1021 gcgaagaagt gaacaattaa atgaatacct ctctaattaa atttgtcaat tctaattcct
     1081 ggtatgaaaa gacagtgacc tgaaaatgta aacgatggga gctgattata aatataggac
     1141 ggtacatgca gtggtgttag agattagtcc ctacttgatt tgtgataact tccccaaatt
     1201 tcttctgcta tacttttctc aacttttaaa aatccaacta agaattttac ctgggggttt
     1261 gggggcgaag ccaccaagtt atcttatcgt tggctgtcaa aactggaagg ttttggttag
     1321 ctggcgatat gattttttgg gtattgtaac cacaatgctt gagctcgcaa agaccgaaca
     1381 aggactttaa gaaatttccc gtatgacaca cggggtcggg gtttacccga gaaaggatga
     1441 aagtgaggaa aagagatgtc tgaacagtac cgtgacattc gaaaagaggt aaatctaacc
     1501 gcagatgagc taaaacagat tgaaaaaatg atggaggttg ataattatcg tcacttttca
     1561 ccattcgtca gggataaaat tttgatgact gatgacaaac agttagctgc caaagaatgg
     1621 ttttcccttt ggcagtctca aaagtttgaa cagatcagtc gagatgtgca tttggttttg
     1681 attatcgcaa gagagaatca ccaagtgact caagaacacg tgtcaatctt attgacctgc
     1741 gttcaagaat tgattgcgga agtcaatcaa gtacagtcac tcagtcgtgg gtttcgtgaa
     1801 aaatacatga gataggaggc tactatggtt tatcgttatc gtaccaatct caaaaaagta
     1861 tttctaacag attcagaatt acaccaattg aatgaacgga ttgctaagag caattgtcaa
     1921 aatttctcag tctatgccag aaaagttttg cttaatccca atatgtcatt tgtcacgatt
     1981 aacactgata cttatgaaca gttagtgttt gaattgagga ggattggaaa taacatcaat
     2041 caaattgcgc gtgcgattaa tcaaagccat ctgatttctc agaaccaatt acaagaattg
     2101 agtaaaggag tcggagagtt aattaaggaa gtggacaaag aatttcaagt ggaggtgaaa
     2161 agactgaagg agtttcatgg tagttactaa acactttgcg acgcacggaa aaaaatatcg
     2221 taggcgttta attaagtata ttctcaaccc tgataaaacg gacaatttga aattggtatc
     2281 tgattttggc atgagcaatt acttggactt ccctagtcat gcagaaatgg tagagatgta
     2341 caatgtcaac ttcagcaata atgacaagtt gtacgaatcc agaaacgacc gacaagaaaa
     2401 acaccaacaa actattcatg ctcattacct cattcaatca ttttctcctg aagataatct
     2461 gacacctgaa gaaattaacc gcattggtta tgagatcatg atggaattga caggaggtcg
     2521 ttttaagttt atcgtagcaa ctcacacaga caaagatcat gttcataatc acatcctaat
     2581 caacgctatt gaccgcaatt cagataaaaa gttgatatgg aactatgcct tggaacgaaa
     2641 cctccgtatg atttcagacc gtatttctaa agtgactggt gcaaaaatta ttgagaaacg
     2701 ttattcctat cgagattata aaaaatatag ggaatctagt cataagtttg aattgaaaca
     2761 acgtctttat tttttgctac agcaatctaa atcgtttgat gattttttag agaaagcaaa
     2821 gcagttgcat gttcagattg attttagtca aaagcatagc cgttttttga tgacagatag
     2881 aacgatgata aaaccaattc gaggacgcca actcagcaaa cgagatttat atgatgaaga
     2941 cttttttaaa acatattttg ccaaacaaga gattgaaagt cgtttaaaat ttttactaaa
     3001 gtctgtttat tcattagaag aattgcatgt aaaggctaaa gagttgaatc taaccatcga
     3061 gttaaaacag aaaaatgtga tgtttaccct agaagaagat ggcaaaaaga taagcctgag
     3121 tcataaaaaa attagcgata agaaattgta cgatgttcaa ttttttaatc gttattttga
     3181 agatagagaa gttagagata ttcaagcatt agaaaatctt caggaagatt ttcagacttt
     3241 tcgagaggag cagcataagg agaaagtctc cgctgaagaa atcgaggaag ccttcaagaa
     3301 atacaaggaa aaacgagatg ctatccatga gtttgagatt gaacttacgg ataatcagat
     3361 agagaagttg gttgatgatg gtgtctatat acaggtttcg tttggtatca aacagagtgg
     3421 actcatcttt attcctaact accagctaga tatttttgag gaagacaatc ataaaaaata
     3481 taaagtctac attcgagaaa cgtcttctta ctttgtctat aataaagaaa acatggataa
     3541 taattgtttc atcaagggta ggaccttaat cagacaattg agcaacgata gccaaaaact
     3601 cccctataga cgaccaactt taaaaagtct taaagagaag atttctgaaa ttaatcttat
     3661 gattgaacta tctaacacga acaaacaata ccaagaaatc aaagatgagc ttgtattaga
     3721 aattgcagag attgatatgc agctagaaga aacccaagaa aaaatcgcca ccttaaacaa
     3781 gatggcggaa gtccttatca atttgaagag tgaagatcat gagactagaa aattagctaa
     3841 gtatgatttt gaccaaatga acatgacgga atcaataatg ttagatcgac tcaatacgga
     3901 tattttaaaa ttacaacagg aacttggtaa tgaaattaat aaatatgagg agatagctag
     3961 aagattggat ttgtttgtga aaattattaa taccaataaa tttacagttc taaaatttca
     4021 cgagaatgcc tt
//
LOCUS       DAVLTG010000090         4008 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLTG010000090 DAVLTG010000000
VERSION     DAVLTG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.091"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            28..1803
                     /locus_tag="VYN12_001988"
     CDS             28..1803
                     /locus_tag="VYN12_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV1416288.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            1804..3189
                     /locus_tag="VYN12_001989"
     CDS             1804..3189
                     /locus_tag="VYN12_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV1416289.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            3212..3823
                     /locus_tag="VYN12_001990"
     CDS             3212..3823
                     /locus_tag="VYN12_001990"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV1416290.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1295 a          584 c          879 g         1250 t
ORIGIN      
        1 tttttggact tagtaaggag aataactttg actcaaggga agattataaa agtatcggga
       61 cctctagtta ttgcatcagg tatgcaggag gctaatattc aagatatttg ccgtgtaggt
      121 aagctagggt taatcggtga aattattgaa atgagaagag atcaggcatc tatccaagtc
      181 tatgaagaaa catctggtct tggtccggga gaacctgttg ttacaactgg agaacctctc
      241 tcggttgaat tagggccagg attgatttct caaatgtttg atggcataca acgcccatta
      301 gatcgattta aattggctac tcataatgat tttctagttc gtggggtaga agttccaagt
      361 ttggatagag atattaagtg gcattttgat tccactatag caattggtca aaaagtgagt
      421 acgggtgata ttcttggaac tgtcaaggaa accgaggtag ttaatcataa aattatggtt
      481 ccttatggag tatctggaga agtcgtttct attgcatctg gcgattttac aattgatgaa
      541 gttgtatatg aaataaaaaa attggacggt agtttctata aaggaacgct tatgcaaaaa
      601 tggcctgtcc gcaaggcgcg tcctgtttct aaacgtttaa ttccagaaga accattaatc
      661 acaggtcaac gagttattga tgcattcttt ccagtaacca aagggggagc tgcagcagtt
      721 cctggaccgt ttggagcagg aaagacagtt gtacaacacc aagtagctaa atttgccaat
      781 gttgatattg ttatttatgt cggttgtgga gaacgtggaa atgaaatgac ggatgtactg
      841 aatgagtttc ctgagttgat tgaccctaat accggacaat caattatgca acggacagtt
      901 ctgattgcta atacttcaaa tatgcctgtt gctgctcgtg aggcttcaat ttatacagga
      961 attaccatgg ctgagtattt tcgtgatatg ggctactctg tcgccattat ggctgattca
     1021 acttcacgtt gggcagaagc gctacgtgaa atgtcaggac gtctagaaga aatgcctggt
     1081 gatgagggtt atcctgctta tctgggaagt cgtatcgctg aatattatga aagagcagga
     1141 cgttctcagg ttctagggct tccagaacgt gaaggaacga ttactgctat tggagctgta
     1201 tcgccacctg gtggagatat ttcagaacca gttactcaaa acactttacg gattgtgaaa
     1261 gttttttggg ggcttgatgc tccgttggca cagcgacgtc attttcctgc aattaactgg
     1321 cttacatctt attcactata taaagacagt gtgggcactt atatagatgg taaagagaag
     1381 acagattgga atagtaaaat aactcgtgcg atgaactact tacaacggga atctagttta
     1441 gaggaaattg ttcgtcttgt tggaattgat tctctgtctg ataatgaacg actaacgatg
     1501 gaaattgcta aacaaattcg agaagattat ttgcaacaga acgcttttga ttcggtagat
     1561 acattcactt cgtttgcaaa acaagaagca atgctaagta atattctcac ttttgctgat
     1621 caggcaaatc atgctttaga gttgggttct tactttacag agattatgga aggtaccgtg
     1681 gcagttcgag accgtatggc gagaagtaaa tatgtttcag aagatagatt agatgaaatc
     1741 aaaattatat caaatgagat tacacatcaa attcatttga tattagaaac aggaggtcta
     1801 taaatgagtg ttataaaaga atacagaact gctagtgaag ttgttgggcc tcttatgatt
     1861 gttgaacaag taaataatgt gtcttacaat gagttagttg aaattcaact tcataatgga
     1921 gaaattcgtc gtggacaagt tttagagatc cacgaagata aagcaatggt tcagcttttt
     1981 gaaggatcta gtggaataaa tttagaaaag tctaaaattc gttttgctgg tcatgcatta
     2041 gaattggctg tatctgagga tatggttggt cgtattttta atgggatggg aaaaccaatt
     2101 gatggtggac cagatttaat tccagagaaa tatttagata ttgatggtca agctattaat
     2161 cctgtatcta gagattatcc agatgaattt attcagacag ggatctcctc tattgatcat
     2221 ttgaatactc ttgtacgtgg tcaaaaatta ccagtatttt caggttcggg cttacctcat
     2281 aatgaattag ctgctcagat agcaagacaa gcgactgttt taaattctga tgaaaatttt
     2341 gcggttgtat ttgcagcaat gggtattact tttgaagaag ctgagttttt tatggaagaa
     2401 ctcagaaaaa caggagcgat cgatcgttcg gttttattta tgaacttggc aaatgatcct
     2461 gcaattgagc gtattgcaac tccccgcatt gctttaactg cggcagagta tctagctttt
     2521 gaaaaagata tgcacgttct agttatcatg acggatatga ctaactattg tgaagcgtta
     2581 cgtgaagtct cggcagctcg ccgtgaagtt ccagggagac gaggctatcc gggatattta
     2641 tatacaaatt tatcaactct atacgaaagg gctggtcgct tagttggtaa aaaaggttcg
     2701 gtgacacaga ttcctatttt aacaatgcca gaagatgaca taacacatcc aattcctgat
     2761 ttaactggat acattactga agggcaaatt attttgtcgc atgagttgta taatcaaggt
     2821 tatcgtccac caatcaatgt tttaccttct ctctctcgat taaaagataa gggatctgga
     2881 gaaggtaaaa ctcgtggaga tcatgctcca actatgaatc aactgtttgc agcctatgcc
     2941 caagggaaaa aggttgaaga gttagcagta gtattaggag aatcggcttt atctgatgta
     3001 gataaattgt atgtgaggtt tacaaagcgt tttgaagaag agtacataaa ccaaggattt
     3061 tataaaaatc gaaatataga agatacgttg aatcttgggt gggaattact atcaattctt
     3121 cctagaacag agttaaaacg tatcaaagat gatttgcttg ataaatactt acctttggta
     3181 gaagtttaat ccggaaatgg agtgattatc tatggtacgt ttgaatgtaa aaccaactcg
     3241 tatggaattg aataacttaa aggaacgttt gacaacagct gaacgtggac ataagttatt
     3301 aaaggataaa agagatgaat tgatgaggcg atttatttct ttgattcgtg agaataatca
     3361 acttcggaaa gaagtggaaa gttatctaat tgataatcta aaatcctttg cagttgctaa
     3421 atcattaaag aattctcaaa tggtggagga attattttca attccatcga aagaaattga
     3481 attatttgtt gagaaagaaa atatcatgag tgtaacagtt cctagaatgc atatgaatat
     3541 tacttctcaa aatgagaaca gtgaatacag ctatttatct tctaatagtg aaatggatga
     3601 tgtatttgct acaatgaata gtttaattta taaattacta agactggcag aagttgaaaa
     3661 aacgtgtcag ttaatggctg atgaaataga aaaaacacgt agacgtgtaa atggtttaga
     3721 atactcgatt attccaaact tgtcggaaac tattcattat atagaattga aactagagga
     3781 ggcagaaaga gccaatttag ttcgtattat gaaagtgaag tagatccttt atttagatta
     3841 ttaattagat gaacaaatat cagcttggat aaggctttaa gcctttctaa gcttttttta
     3901 ttgacagtat caggatatct ttttcaaaat tttggtttgt tagataatga aaatgtttct
     3961 actaatctag atttaggatt agtaaatcgt aaatgtaatt atatagaa
//
LOCUS       DAVLTG010000091         3993 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLTG010000091 DAVLTG010000000
VERSION     DAVLTG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.092"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            371..598
                     /locus_tag="VYN12_001991"
     CDS             371..598
                     /locus_tag="VYN12_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416291.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3768
                     /gene="nanA"
                     /locus_tag="VYN12_001992"
     CDS             886..3768
                     /gene="nanA"
                     /locus_tag="VYN12_001992"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1416292.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTESAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1364 a          660 c          882 g         1087 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacgctt ataaaaagtg atagaatcta tttttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgagat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaacaaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagttcga ctcagaagta
     3301 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaact
     3361 cagtatgata gcaagacctt gttgtttgca gtagataagg aagatatcgg acaggaaatt
     3421 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3481 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3541 acagggggag ttaatggtac agagtcagct gttcatgaaa tcgcagagta taagggatct
     3601 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3661 caggcacttc ctgaaacagg aaacaaggag agtgacctcc tagcttcact aggactaaca
     3721 gctttcttcc ttggtctgtt tacgctaggg aaaaagagag aacaataaga gaagaattct
     3781 aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg ctatcttttt
     3841 ttgatgacat tcaggctgat acgaaatcat aagaggtctg aaactacttt cagagtagtc
     3901 tgttctataa aatatagtag attgaaataa gatgtgaaca actctatcag gaaagtcaaa
     3961 ttaatttata gaaaaatttt agcagtcaag gtg
//
LOCUS       DAVLTG010000092         3946 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLTG010000092 DAVLTG010000000
VERSION     DAVLTG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.093"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            32..346
                     /locus_tag="VYN12_001993"
     CDS             32..346
                     /locus_tag="VYN12_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416293.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1030..1191
                     /locus_tag="VYN12_001994"
     CDS             1030..1191
                     /locus_tag="VYN12_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416294.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1283..2962
                     /locus_tag="VYN12_001995"
     CDS             1283..2962
                     /locus_tag="VYN12_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1416295.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLHIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENISIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMSGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGNKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3230..3796
                     /locus_tag="VYN12_001996"
     CDS             3230..3796
                     /locus_tag="VYN12_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416296.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         1534 a          494 c          825 g         1093 t
ORIGIN      
        1 aaattaccga tagacagtag aggtactcca gattggaatt acatggaaag atatagagat
       61 agataaagag agagagggag agatagataa aaagtccacc cccatttttt atggagaatt
      121 caaaaatgta aggttaagca aagaagaata taaaaatcta aaagaaaaat taaactcaca
      181 cacagatata atgataaata aactatccag atacatggaa agcagtggta agacctatca
      241 aaaccactat gtgacaatct taaaatggta tgaagaagat aaagacaaac taagacagaa
      301 aggtttaaat aaaaaaatga attatgatgt aggagaatct ttatagataa aaagaggtgg
      361 aaaggcacta ttaaagactt taagtctaaa aaggtatcaa agtatgccag agataaaaaa
      421 atataaatat gacactttaa aggcgattag aaaattaaag aaatgctaga agacttttag
      481 atgacagtta ccaagagggt ctaattttca ctgctattta tgcagtggga attggacctt
      541 tttatataag caaattctat ttcaaaattg gttaccaaga aagacttctt ttcactgtta
      601 agtataagag ggtaatttat agaattttgt tacatcaaga taaatatttt ctgatggtca
      661 aattttaaaa agattaataa ctctcgataa attttgaacc ttaacaattg aatagaccaa
      721 gacaagacgt taattatttt tggagcgtaa taacctatcc gtcaagatct ttcggctgaa
      781 taattcggca aaaaaagttc tgctaagcaa aaagaaagtg agcgataagt aagagtttga
      841 atatagggag ggatacccta tccgctatga agaaaatgag ggtaatgata cttctaaggt
      901 tgaagccggc tcatccggaa tagaggcgga agtgagattc ctatgttgct aatccaaagc
      961 acttgtcaat gtcaaaaaac ttaattaaac aaataattat tagatataaa actttagagg
     1021 aggtatatat tggacaatga ctggaatgga ttggctgatt taatagcaaa tctgattgca
     1081 aaatatgctg gtgctttaga tttagataat ctacccgatc caacgccagc aaaaaatcaa
     1141 gagatgaaaa atagttttga catggcaaaa acacaaattg agacggacta ataaaagtgt
     1201 tataatatac ttgaaatgat agtccaaact taaattaaaa aaattatata tgatatagaa
     1261 aaattatatt gaggttaata ctatgtcaaa agaaaaaata aaagtatacc tctatacacg
     1321 agtatctacg tcaatacaga tagaggggta ttcgttagag gcacaaaaat cacgaatgaa
     1381 agcttttgct atttacaacg attatgaaat tgttggagag tatgaagatg ccgggaagtc
     1441 tgacaagtct attgaaggta gaatacagtt caatcgaatg atggaagata taaaatctgg
     1501 aaaagatgga gtatcttttg ttcttgtgtt taagttatca agatttgcaa gaaatgccgc
     1561 tgatgttctt tctacacttc atataatgca ggattatgga gttaatctta tctgcgttga
     1621 agatggcatt gattcatcta aagatgctgg gaaactaatg atttctgttt tatcagctgt
     1681 ggctgaaata gaaagagaaa acatcagtat tcaaacaatg gaaggtcgca ttcaaaaagc
     1741 aagggaagga aaatggaatg gtggctttgc tccgtatgga tataaacttg aagacggcaa
     1801 gctgtttata aatgaggaag aggcagttgc aataagaacg attttcgacc agtatgtaaa
     1861 tactacgata ggagccaatg ggatatctaa atacttagag aatcatggaa ttagaaaaat
     1921 cccaagacag aatggtaaga atcctttgtt tgatgcaggt cttataagaa agatattaaa
     1981 gaatcctgta tataatggga aaatagcatt tggaagaaga actttagaaa aagttcatgg
     2041 tacaagaaat gaatataagc aggttgaaca agatgaatat ctaatatctg aagggataca
     2101 tgaagctata gtttccgatg aagtttggca agctgctcag gttaagctaa aatctcaagc
     2161 aaagaaatat gagcatgtga ataaaggaaa agatacacgc acacacttgc tttctggaat
     2221 tgtaaaatgc ccgatatgtg gagtgggaat gtctgggaac aagtgtatca agaaaaagaa
     2281 agatggcaca aagtataaag atttttatta ctatggttgt aaccataggc agatgataag
     2341 aggtaataag tgtacattca gtaagcaaat tagagaagaa ttgttagatg atgctgttgc
     2401 agaggtgatt gtcaagatag taagtaatcc gaaatttgct tctatgatgc aagaaaaaat
     2461 caacatgaag gtggatacct ctgaaataga aaaagaaata gataattacc aaaaggaatt
     2521 gagaaagagt cattctacaa agtttaagct aattgaggaa atagataatt tagatgttga
     2581 agataagcat tataagagaa ggaaacagga tttagatgat agactatatc gtatgtatga
     2641 caaaatagat gaattagaat catcactaat tgatgcgaaa gcaaagaaac agactattga
     2701 agctgaaaag cttacaggag ataacatata taaggttctg atctattttg ataagctcta
     2761 taaagtcatg aatgatgtag agcgtaggca gttaatttca gctttgattt ctgaaattca
     2821 agtttatgaa gaaaaacaat ctaacggaca atggctaaaa tccattactt ttaagctacc
     2881 aattatagaa gaaaatctca acatagattt ggacaatgat gaacaagttg aatgtgtaag
     2941 tttattagag aaacgtagtt aatcctcaaa aggttcccca aactttttga gtcccactga
     3001 cgcatcacgc tgaggcggta tcactgcttg tacgagttga agcatcagcg aagtaaaagt
     3061 agatgttcag ccaatgcgac gaggtgagac cgaaggtcga taaggtgtgt tctgggtata
     3121 ggactcgtaa agtaagtagg aaatatgatg agatgataca gagagcctga attggtcagg
     3181 tgacgtgctt atttacatta gcctgataat gaaaatggag agattatcga tggttatatt
     3241 ggaattgtac caaaatgatt attctaaaga tttagtagca tttgattcca tagaagatgg
     3301 gaaagccttt gtagctcaaa tcccgggata cactctggaa acagaagatg gttttgaagt
     3361 ggagtatttt aatcctaaaa acataccgga ttatatggaa attattttta acggaaatat
     3421 tgttccttta tctaaattta tgttcgatcc tggggaaaat gtaaacatta tttggaaaga
     3481 gatttcaaat ttatccctca aaaatgatag agtgatcgaa ggatattcaa aaattgatgc
     3541 atatgtcgtt aacaaccatg aagttaaagc ctatgtcgaa acaagagaaa cgaactatcg
     3601 taaagcaaaa gacttcttag aaagccgcgg atatgaaatc gacagaagct ttttcggaag
     3661 tgaagacggt gaagcgattc tttacagaaa aaaagggatc gaagtttggc atttcttgtg
     3721 tcacttagac ccaatgtttg tagagattga agatgtagaa ggatatgtta aagaagaagt
     3781 tggagagatt caatagtcaa ccaaagttcc ttgtgagtat atacctttgc tagtaaaaga
     3841 gtcaaaacgt tataacgaag gggggtaaga aaacccttga gtgtaagtct ttttcttgtt
     3901 tagagggaaa gtattagagt agccgctcat aatttatact agattt
//
LOCUS       DAVLTG010000093         3831 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLTG010000093 DAVLTG010000000
VERSION     DAVLTG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.094"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..246
                     /locus_tag="VYN12_001997"
     CDS             <1..246
                     /locus_tag="VYN12_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416297.1"
                     /translation="GIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVV
                     INEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            561..1538
                     /locus_tag="VYN12_001998"
     CDS             561..1538
                     /locus_tag="VYN12_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416298.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            1915..2289
                     /locus_tag="VYN12_001999"
     CDS             1915..2289
                     /locus_tag="VYN12_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1416299.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2497..3399
                     /locus_tag="VYN12_002000"
     CDS             2497..3399
                     /locus_tag="VYN12_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416300.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3455..3787
                     /locus_tag="VYN12_002001"
     CDS             3455..3787
                     /locus_tag="VYN12_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1416301.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
BASE COUNT         1292 a          492 c          694 g         1353 t
ORIGIN      
        1 ggaatcattt acgataatga agcattaaga gatttgtcaa aacaatattt aaacaaaaat
       61 atttcggaat tacaagatgg ttctttcgag ggcggtatac aagatgctgt tgcctctaaa
      121 caaatagtag ttataaatga atttatagct tgtttaaatt ccagatgcgt gccatcccaa
      181 tatgatagat ttttttataa agatagacct tatatttttt ccagaaagag tcctattaag
      241 gggtgaaaat ttgttacatt tggattaaca agtgtcctag ggattagaaa taactctagt
      301 atagctagat atttttgagt aactagaaat atcattaggc tacccatatg attgccagaa
      361 aagatggctg atgaatctta tttatactgt tgcagtaggc attgtctagg ataaataagc
      421 tatcttgatg ggggaaattg gaataatttt agtagaaaca ttaaaggatt atggataagt
      481 agcgcaggat taggtgatgc aatgtgctaa gttggcttgg tgttagcagt agtattattt
      541 aacaatggaa agtagactaa atgaaaaata aacgttattt ttttgacaca attttaataa
      601 ttttactgct tataagcacg atattttgtg tcagcccagt atttataaaa ttggacatct
      661 taggaactcc ctctcatgcc atcttaacct ttgtattggc gataccgtta ttctatattt
      721 tgtctcaatg cttacatact ttgctattac tagtttcctc aatcttttgt aaattaagac
      781 caatttattt ttattttata tttgtgatca ttataggagc taggaaatac tatcgaattc
      841 tctttcacca actaatggga tttagtccag gaatagcagt gttttataag gagagtcaaa
      901 caactaagaa tctgtttaaa ttttactact tcttgtactt tacaacacta atttcatact
      961 attttttctt tacttttgtg tatgacaaac cgttgctttt gcctcttatt tcattttcta
     1021 ttatcatagc attagtacaa aaactttata gaattgagaa tcaacaatta tttctgttaa
     1081 aatcaaaggt actaacaata ctggaatcta agaagaattg tgagtttaat cttcaggatt
     1141 atcatgaaat ttggaaattg caatcaaaat ctgagttgcc atgcgtggct ttatcttata
     1201 tcagtttaat caagccatat ctttcagaga gtgtgcgtga acaaattgat ttattagaag
     1261 ttaagcgatt taaaaaaata aataatccaa tatcacttta tggtatgttg gatgttataa
     1321 aattaaatct atatttacgg cattataatg aaaaaaataa atatgaatca atgttaaaga
     1381 aaattttaga ggtaagacca gactttgttt taatcgagca gaatattgat gatagtttaa
     1441 atagctcgca accattatct ttatctttag ccatttcaga aatccaactt ttgcttgaag
     1501 tgtatatagg gatcaaacat gtttcaatta ggagataaaa ctagaataat atttgccatt
     1561 ataggggcaa gttgcatatt agtcagtatg tatcttattc cacttattaa aactgagaat
     1621 aaattttggg aaatactttt atttatatta ggtgtattgc taattggaat tgcgttacta
     1681 agtcaaaaaa aataaatttt gaaatagtat tagtgagttc gcaatcattt attgctagtg
     1741 gtttagaact gttaagtttc aaacaataat tgattttaaa ccttaggtaa cctataaaaa
     1801 caaataaggt agagaaagga tatcttatct aggtagctaa gtgataaaaa cacagtcgtc
     1861 tatcacttgt taggaaacga tcctaactat gcttaataaa aaaggagaaa ataaatggaa
     1921 ctcgtattac caaataatta tgttgctctt gagcaagaag agatgatgta tcttgatggg
     1981 ggattttcta ttctgagatg gcctgttgca acagccatta atatagcttt taatggtgtt
     2041 ttaggtggag gagcaatcag tctagttaga aattatattc gtaattatgg tttgcggcga
     2101 gttacaagcg caattgctgg agcagctgca agatatgttg gggtacgagt tgcaaataga
     2161 gtggcaggat ttgcactgtc tgctattaat ggatttgcag cttggatgtc aattggcgat
     2221 gctattacaa caatctgggc caacaatgat gtaaatagga gagacccaaa tttaaacgcc
     2281 ttgtggtaac tagatatggg tattaaaatg gaaaaaattt ttgttattat tttttttgta
     2341 tgtctattta tatcatccat aactttttta gcctatgatt ttgttagcga agaaataaaa
     2401 aagttgatta tttggatgaa tgtcgttttt ttgattttaa tcatagcaat gataatttat
     2461 ccaaaattaa gaaaatgata aggacactgt aaaattatga tacgtaaact aatcattttt
     2521 ttattaatgc tccctctttt tgtcttgtgg ctagagttgc atttgttagt gagtaacttg
     2581 caattgaatc tagaaattcc ccttgatttt gtggttagta cgagtcttgc tttctgtagt
     2641 ttgattttat caaaaatagt tttagacata ctatacgcat tgaaagattt gtacaagaaa
     2701 gaagctctta ttacgatttt tccttttatt tttataggca ggaagaaagt aaatgtgagg
     2761 ttctcgccct atttttcatt ccatcgtaaa agtttgtcgc ctgatgattt aagatctagg
     2821 attatatgga gttttattct tgaaattgct attattctag tatttatttt aaaaattcct
     2881 tttgcaatca tcatgcttac tacaatattt ttctggacta taatggatat caatcatctc
     2941 gtttttaata agacggaatt tctttttaat caaaataaat gggaaaaaga agattcgttt
     3001 gaaagcgatt tgacgaaaac gttaaaggat aagatacaaa aatcagagct aagttattct
     3061 gacttaatgt ctcttcagct gtatgatgcg atgaaccaat ccaccttttt aacggatagt
     3121 gaactttttg aggatatttt gaaaaaaatc gaagattctc ataacaccct tctgtgtaca
     3181 ggtcttgtcg agttactgct gtatgaaatg tctattagta acaataacaa ctggtccaac
     3241 aaggttgata aaattaggat acacctcatc agaatcaatc aattagattt tttctattat
     3301 acaagttggt taaggcaaaa ttttgatttc tgtatgaata gagagtatca taaaatgaaa
     3361 tctcggaaat tattactgag taataaaaag atagtttaag ttcgtcctat ttgtaaaaca
     3421 aatgaaacaa tttcaactaa ggaggagaaa acaaatggaa cttgtattac caaataatta
     3481 tgttgtgatt gatgaagaag aaatgatgta tcttgatggg ggagcttatt taagcaagcg
     3541 tgcttgtcaa ggaatttgcg tagctttagc tatgagttca ggaactttta tagcattagc
     3601 tggagctgca gttttaacca aaaaactaat aaactatatt aaggttggag gtcttggagg
     3661 ctggcttatt ggtgcagcag caggaaaaat agcttactgt attggatatg gtgctcttaa
     3721 tagaggttgt gatattagcg ggaaccctta tccttgggat ggatttatat ctgcgacagt
     3781 aagatgaata atgtagataa gattcgaaaa atacatatta tcgtatgttg g
//
LOCUS       DAVLTG010000094         3775 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLTG010000094 DAVLTG010000000
VERSION     DAVLTG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.095"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..170
                     /locus_tag="VYN12_002002"
     CDS             <1..170
                     /locus_tag="VYN12_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1416302.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(536..1846)
                     /locus_tag="VYN12_002003"
     CDS             complement(536..1846)
                     /locus_tag="VYN12_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1416303.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /locus_tag="VYN12_002004"
     CDS             2083..2955
                     /locus_tag="VYN12_002004"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1416304.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..3775
                     /locus_tag="VYN12_002005"
                     /pseudo
     CDS             3086..3775
                     /locus_tag="VYN12_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1191 a          640 c          830 g         1114 t
ORIGIN      
        1 gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc
      241 tatttgtcct gttcttattt catttcacta tatctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag atttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggtt gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ccttagctaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg tgggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttgtt gcaacgttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacacttg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtaattgc
     2041 ctctagtgct tacaagtgat attaaaaata gaggacttag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcggga ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcatgctaaa agacaatcac attgcggcag taggtagtgt tcagaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacacaatg tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg
     3181 taataccatt tatggctggt taaagctaaa agagaaaaca ggagagctaa accaccaagt
     3241 aaaaggaaca aaaccaagaa aggttgatag agatagactt aaaaactatc ttactgacaa
     3301 tccagacgct tatttgactg aaatagcttc tgaatttgcc tgtcatccaa ctaccatcca
     3361 ctatgcgctc aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag
     3421 acccagaaaa agtagcctta tttcttaaaa attttaatag tttaaagcac ctagcacctg
     3481 tttagattga tgaaacagga ttcgatactt atttttatcg agaatatggt cgctcattaa
     3541 aaggtcagtt aagaagaggt aaagtatctg gaagaagata tcagaggatt tctttggttg
     3601 caggtctaac aaatggtgag ttaatcgctc caatgactta cgaagagatg atgacgagcg
     3661 acttttttga agcttggttt cagaagtttc tcttaccaac attaaccaca ccatcggtta
     3721 ttattatgga taatgcaaga ttccatagaa tgggtaagtt agaactttta tgcga
//
LOCUS       DAVLTG010000095         3683 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLTG010000095 DAVLTG010000000
VERSION     DAVLTG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.096"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            37..1149
                     /locus_tag="VYN12_002006"
     CDS             37..1149
                     /locus_tag="VYN12_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416305.1"
                     /translation="MQMEIKAYNLSKDIKDDLYKKMEDSERVHLKAEVTTILTLSISS
                     IFSFISLAVVIFVGVNLIINKEINSLYLIGYLLAAMKIKDSLDASKEGLMEIFYLSPK
                     IERLKEIQNQDLQEGDDYSLKKFDIDLKDVEFAYNKDAKVLNGVSFKAKQGEVTALVG
                     ASGCGKTTILKLISRLYDYDKGQILINGKDIKEISTESLFDKVSIVFQDVVLFNQSVM
                     ENIRIGKQDASDEEVKRAAKLANCTDFIEKMDKGFDTVIGENGAELSGGERQRLSIAR
                     AFLKDAPILILDEITASLDVNNEKKIQESLNNLVKDKTVVIISHRMKSIENADKIVVL
                     QNGRVESEGKHEELLQKSKIYKNLIEKTKMAEEFIY"
     gene            1160..1744
                     /locus_tag="VYN12_002007"
     CDS             1160..1744
                     /locus_tag="VYN12_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1416306.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1744..2439
                     /locus_tag="VYN12_002008"
     CDS             1744..2439
                     /locus_tag="VYN12_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1416307.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            2427..>3683
                     /locus_tag="VYN12_002009"
     CDS             2427..>3683
                     /locus_tag="VYN12_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416308.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIK"
BASE COUNT         1360 a          463 c          699 g         1161 t
ORIGIN      
        1 agaaaaaact cagaaagctt tcaagaaaat atcgaaatgc aaatggagat taaagcatat
       61 aatttatcga aggatattaa agatgactta tataaaaaaa tggaagatag tgagagagta
      121 cacttaaagg cggaagtaac tacaatttta actttgtcta tatcttcaat atttagcttt
      181 atatctcttg ctgttgtgat atttgtcggc gtaaatctaa ttattaataa agagataaat
      241 tctctctacc ttataggata tttactagct gctatgaaga taaaagactc tttagatgca
      301 tctaaagagg gcttgatgga aatattttat ttatcgccca aaatagaaag attaaaagaa
      361 attcaaaatc aagatctaca agaaggcgat gactatagct taaaaaaatt tgatattgat
      421 ctaaaagatg ttgagtttgc ctacaataaa gacgcaaaag ttttaaatgg tgtaagtttt
      481 aaagctaagc agggagaggt cactgctttg gtaggtgcaa gtggctgcgg taaaacaact
      541 atcttgaaac ttatatcaag actttatgat tatgacaagg gacaaatctt aatcaatggc
      601 aaagatataa aagaaatatc aacagaatct ctttttgata aggtctctat agttttccaa
      661 gatgtggttc tctttaatca aagcgttatg gaaaatatta gaatcggaaa gcaagatgca
      721 agtgacgaag aggttaaaag agcagcaaaa cttgcaaatt gcacagattt tatagaaaaa
      781 atggataaag gtttcgatac agttattggt gagaacggag ctgagctatc aggaggagaa
      841 agacaaagat tatcaatagc cagagccttc ttaaaagatg cgccgatatt gatcttagat
      901 gagataacag caagccttga tgttaacaac gagaaaaaga ttcaagagtc tttaaataat
      961 ttagttaaag ataaaactgt tgtaatcatt tcacatagaa tgaaatccat agaaaatgca
     1021 gacaagatag tagttcttca aaacggaaga gtagaaagcg aaggtaagca tgaagagctt
     1081 ttacaaaaat caaaaattta caaaaattta atagaaaaga caaaaatggc agaagaattt
     1141 atttattagg aggactacaa tggataataa aaaattaaaa gtaaaagatt tagtaagcat
     1201 cggtgttttt ggcgtaattt attttgcctt catgtttgga gttggtatga tgggcttgat
     1261 tccaatattg ttcttaatat acccgacagt attagccata gttgcaggaa ctgttgttat
     1321 gttatttatg gctaaggttc aaaagccatg ggcactattt atatttggta tgatatcacc
     1381 acttgtgatg tttgcagctg gtcataccta cgtagttgtg gttttatcac ttatagtaat
     1441 gataatagca gaattaatta gaaagattgg taattataat tcatttaaat acaatatgct
     1501 ttcttatgca atcttcagca catggatatg tagctcttta atgcaaatgc ttttagcaaa
     1561 agaaaaatat atggagtggt ctttgatgac gatgggaaaa gattatgttg atgtattaga
     1621 aaagttaata acttatcctc acatggcttt agtagcctta ggtgctttct taggaggaat
     1681 tcttggagca tatataggca aggctctatt gaaaaaacac tttgaaaaag caggcattgt
     1741 ataatgccta ctttttcttc aaatgctccc tttaatccca atccgatctc taagatatta
     1801 gtcgtattta tcacaggctt aactgttatg catagcataa acatccgttt tgagctggca
     1861 attgtttgtc ttattggtat tttgctttat ttgaatggat acaaaaaaac acttttcaaa
     1921 tggattatat tgtgtgggat actttactcc ttgcctaatt ttatggtgtt atctgaatta
     1981 aaccctatag ttaagatgtt tttgagtata cctattgtta ttagaatgtt tattttacca
     2041 tttatggcag caagctttat gataaagacc tcggatgtag gcgcaataat ttcatcgatg
     2101 gataagctta agatttcaaa gaatgtatcc atacctattg cggttatgtt tagattcttc
     2161 ccatctttta aggaggagaa gaaaaacatc aaaatggcta tgagagtaag agggataaat
     2221 tttaaaaacc cagtcaaata tcttgaatat gtttctgtgc cactactcat tatatcatct
     2281 aatatatcag atgacattgc aaaagcggca gaaacaaagg caatagaaaa tccaattgcc
     2341 aagaccagat acattcgcgt aaagatacag ctaattgatt ttgtttatgt tttagcggtt
     2401 gttggactta ttgtgggagg cttaatatgg ttgaaataaa aaatttaagt cttgattatg
     2461 gtgaagagca tatattagat gatatatcac tatccatagc cgagggagag tgcgtgctat
     2521 ttacaggaaa aagtggaaat ggtaagtcat ctttaataaa ttcaatcaat ggactagctg
     2581 taaggtatga caacgcaaag acaaagggcg aaatcattat tgatggtaag aatataaaaa
     2641 atttggaact ttatcaaatc tcaatgcttg tttcaactgt ttttcaaaat cctaagacat
     2701 atttttttaa tgtcaatacg acattagaat tattatttta tttggaaaat atcggtcttg
     2761 caagagaaga gatggacagg cgtttgaagg atatgcttaa gatattcccg ataaaaaatc
     2821 ttttgaacag aaatatattt aatctatccg gcggtgaaaa acaaattctt tgcattgcag
     2881 cttcttatat agcaggtaca aagattatag ttatggatga gccttcatcg aatttagata
     2941 ttaaaagcat aagtgttttg gcaaagatgc taaagatatt aaaagagaaa ggtataagca
     3001 taattgttgc agagcataga atttattatt tgatggacat agttgaccgt gtatttttaa
     3061 tagataaagg aaagcttaaa aaaacttata ctagaagtga atttttaaag ctagataaaa
     3121 atgaattaaa tgctttaagt ttaagagata aagaattaag taaattaaaa gttccttatt
     3181 taaaagaagg tggagagtat cagataaaaa atcttagcta caaatttact gatgatgagt
     3241 gtttaagctt aaaagatatt tcattcaagc ttgggaaaat ttatggcata ataggatcca
     3301 acggacgagg aaaatcaacg cttttaagat gtttaatagg tcttgagaaa aaatcaaaag
     3361 aagaaattta ttttaaggga gagaagctat ctaaaaaaga aagactcaaa aactcttcac
     3421 ttgttatgca agatgtaaat catcaattat tcacagatga agtattcaac gagcttagat
     3481 taggagtaaa gaattttgat gaagaaaagg cgaaaatcat tttaaaagat ttaggcctgg
     3541 acgaatttat tgaaaggcat ccgatgagtt tatcaggagg gcaaaagcaa aggcttgcaa
     3601 tagcatctgt tatgtgcaag acttctccat ttgtcttttt tgacgaacct tcaagtggta
     3661 tggattattc caatatgata aaa
//
LOCUS       DAVLTG010000096         3501 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLTG010000096 DAVLTG010000000
VERSION     DAVLTG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.097"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            76..414
                     /locus_tag="VYN12_002010"
     CDS             76..414
                     /locus_tag="VYN12_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416309.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            480..2462
                     /locus_tag="VYN12_002011"
     CDS             480..2462
                     /locus_tag="VYN12_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1416310.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            2459..3082
                     /locus_tag="VYN12_002012"
     CDS             2459..3082
                     /locus_tag="VYN12_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1416311.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            3079..>3501
                     /locus_tag="VYN12_002013"
     CDS             3079..>3501
                     /locus_tag="VYN12_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416312.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKE"
BASE COUNT         1267 a          462 c          632 g         1140 t
ORIGIN      
        1 taaagtaata tggagggact aaaaagagac tattatttaa tcttcatcaa atatttaaat
       61 tcaaggagaa gtaaaatgaa aaaaagaatt aataagaaag catctgtttt tctagttgca
      121 agtgttttca gttttagctt tgctactaca gctagtgtcg ttaacgcagt aacggcacac
      181 cctgctccaa gtcccattat tgatgtatgg gaatatggtg taaatgataa ctatggttat
      241 tcgaattact ttgttagttc tccaagtaat attggatcaa aatcttcagt aacgaatttt
      301 tggggaacag ttaaagctca ggataaaaaa gattatggat gggcatattc aagtgcaaca
      361 aaatcttgga acgatgttcg cttaaatgca tattgggatt attatagatt ttaaaaataa
      421 tttatgaaaa caagagaccc aattataaga ttgggtctct tgtaatatgg taattgctta
      481 tgaaattaaa attatgtatc attggattct tcttttgttt gattgctaca attggtctgg
      541 tcactattag tgataccgaa atccccatac ctttaccaat tgatggagct ttttctatcc
      601 aaggaaaaag taatctttct aataacgaaa tatacgaaat ggttcgtgac ttatcaaaaa
      661 cggaaaaggt taccatttac aagccaatcg ttcagagttc gggtcagttg aagtatgtaa
      721 attttgatga tgtaaataat gaacaattaa agtcagcacc aatagtaggg atgtattaca
      781 cacttgggaa aatggatgta gacagtttga aaccacttac gatgacggga ctacaaacag
      841 tctatatggc ttatccttgg tatataggag gaatattaca attcactgga actttaagaa
      901 tactgttaat gggttcaatt tatttaactt tattagttgt tttatttgtt gttaggacga
      961 ggcagatcaa agaaggagtg atacgacgtt ctttgggctt gcctatatac gacttaagaa
     1021 gagagtatgg catttctctt atttttgaac tgattatgat ggctttattg atgatttctt
     1081 acagttcttt tttgggtaat ggtttcttca cctatagttc taagttattt ttctctctgc
     1141 ttttaacgaa ttttatacta tttcaaatca ttgatcttat tacttttgtt ttattttggt
     1201 tgacgattca gattgaaaag cctattgaaa ttattaaaaa caaggcaaaa aacaagctta
     1261 tttttgtcgt atggcttgct attatttcga ttatcatcct tgtctcagga gtttttttac
     1321 aagaaacaaa gagtagtcaa tctagtatta acatacagat acagaattta gtaccatggg
     1381 atacagtaaa agactggaga aggattgagt tccttggaat tgaaagtaac tctactaaaa
     1441 atagagaagt taatgattca gatggtcagt atctacagat agttgctgcc ttaaaaaact
     1501 tagatttctt atatatagaa cggtcttcag catatgttcc agatttcatg aaaacttcac
     1561 atgttataga aaatttttct aaacaattag aaaatgacgg gataacgaat ccagaaataa
     1621 ataaagagtt aatttatatc aaccaaacag gtgctaacct acaaaataaa gtgaatggaa
     1681 caaactatca tcttttagat aataagatag caaccatcta tattcctgag aagtggaaag
     1741 aaaaccagaa atctattgag aatacagttg tagcagaaca atttattgga acaaactata
     1801 caagagaaca gcttgcagtt caaataattc ctgatgggga aaaaattttt tattttaatg
     1861 aggatgctga taataatctt aaaatgaaag atattttacc gctggcaaat gtagcagata
     1921 gcaaagataa tatagttgtt gtgttagata cggacaaaat gatggaaaat aataagtttt
     1981 ctttggctag taacatacta tataaatctc tttttagtcc tgaagcggta aaaaaaataa
     2041 atgagatgac tgtcctgttg aatttctcaa tgaatccagt agatgtttac caaattgtga
     2101 aattaaagat tcaatcctta gagcaccaaa ttttactttc acaaatcttg cagaagataa
     2161 tttacagtat tgtctttata ctcatttatc aatatgtcca actttttatt actctaaaac
     2221 agaatgaata tgtgaaaaaa atcattttgg gtctgtcaaa aacatatata gcaatttcaa
     2281 gtctcaaata ttttatgatg actattacaa tggttattct atttacattt cttatgacag
     2341 ggcaaataga gttgctatat attggagcgg cttctctgct agttttgatg ttgtcaatca
     2401 taatgagttt tagaaaatta tctgaaagct acactaaaat tttaaaagga gatgaatcat
     2461 gacaattgac cttttgaacg tttcaaaaag tttcggctca aagaagatct ttacagactt
     2521 aaatttaata tttgaatctg gaaaaagcta tgcattgatt ggaggttctg gctccggtaa
     2581 aagtaccctt cttaatatta taggaagatt agaaaaaatt gacagtggga atgttttagt
     2641 tgataaacaa gatatttgga agataaaaga aagaactttt tttaaaaata ctgttggata
     2701 tgtatttcag aattattctt taatagataa caaaacagtg tatgataatc tgagccttat
     2761 cactaaagac aaaaaaacaa taactgacgt acttgaaaaa gtaggactgt caagtgacta
     2821 tttacaccaa aaaatatatg aattgtctgg agggcaggct caacgtgtag ctattgccag
     2881 aatgttaatg aaaccacgta aaattatctt agcagatgaa cctacaggag ctttagatgg
     2941 tgagattgga aaagaaatta ttcgtttact attgaatgaa acagctgaag ataaatatgt
     3001 cattatagcg acacatgatc cagctgtcta taacgaagtt gatgtgataa ttgacatgaa
     3061 agatataggg tataaggtat gaaaaagaaa atttatattg ctttgatctt tgtaactggg
     3121 gtactcgcca ttttcttttt tggaaaacaa atgattacaa aagaaaatat caataagcca
     3181 acggtagagt taacaatcta tacgctttct tctagtgata cagaaaaatg gaataaagtg
     3241 agacaagtag aaacggaaga agctatatac ttcataactg taaaagaagt atcatcttca
     3301 gaagaagtat tttcaaacat cattgcaaat ggagctgcta cggggttcgg agttcgtgaa
     3361 gaagaagtga agaaattcaa taatggttta ggagacacca tagaggactc taagcataat
     3421 aaactaattg aaatagaatt ttttactttt tctgatgatg gcgcgggatt tgtggtagca
     3481 aactttgact acggtaaaga a
//
LOCUS       DAVLTG010000097         3486 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLTG010000097 DAVLTG010000000
VERSION     DAVLTG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.098"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            129..488
                     /locus_tag="VYN12_002014"
                     /pseudo
     CDS             129..488
                     /locus_tag="VYN12_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            complement(608..1078)
                     /locus_tag="VYN12_002015"
     CDS             complement(608..1078)
                     /locus_tag="VYN12_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1416313.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1095..3368)
                     /locus_tag="VYN12_002016"
     CDS             complement(1095..3368)
                     /locus_tag="VYN12_002016"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1416314.1"
                     /translation="MRFNQYSYINFPKENILSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSENELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVSLPHKIELEKPQLNLVQPQGKAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFATLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNDRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         1042 a          601 c          775 g         1068 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaagac ctacggcaag gcgacgttga cgcggattga agagattttc gaagagtata
      481 aatcttccta ggataaagca aaacgcatag tatcaagggt tttcagcact tgatactatg
      541 cgttttctga tgttaaagac tttctaccag gttttttaaa agcataattg ttagttgtag
      601 tcatttatta ttcttcaaag aaaaatggtg gggcgaattt tttcagttct tcaaagcact
      661 tttgagcagt atctgcatct tcacagatga taagacagac atcattacca caaagggtag
      721 cgatagcgtc agggaagctc aaagtatcaa tgatagaacc aaaggattga gccagtccag
      781 gaagggtttt tagtaggact tggtgttgaa ctgggcgcat ccagacaagg gcgtcttcca
      841 tgtagagttc gagacgtttt tcccattttg agatggaacc attgttaaga acataataag
      901 cgctatcttc ttcgcggact tttgataggt tcatattttt gatgtcgcgt gagagggttg
      961 cctgggttac ttgaatgtcg ttctcagcaa gaagggcttg caactcagcc tgtgtatgaa
     1021 tcttgttttt tgtgataaga gcgcgtataa gttggtggcg gtgttctgat ttattcataa
     1081 taatgtaact ccttttagca aggtaaggta agcatggact gagcgaggtc gacagtcaag
     1141 tggtagtctg tattgtcacg gatggtgatt tcaaagtcag tagtatagag gactaaacgg
     1201 agagtgtctc cttcttttag cttgtaaata gttggctgca gttcaaattg aacgtccatc
     1261 cattcatctg cagtaatatc ctctactaac agtaaatcat ttctattttg taaattaagg
     1321 taaccttttg tcacgactcg ttgtgcctct ggtctaaatg gcaattcaca gagattttcc
     1381 aacatgtgat agcgaccgtt atcaatggtt ctagcactta aaatagctgg ataaggttgt
     1441 aggtatttct tttgcccaaa ttctagcagt tgggcagata agagcccctt gtttgtactg
     1501 gatttgatac gaagattgag ctgagcgcga ccgtttaggt ggagatcttt agtcacagga
     1561 aggttaatag taatctgatt ggctttccct tgatagagct ctgtattgaa ggtttggtat
     1621 gtcttaccat agcgctcaaa atccttatct gggtactggt tttgaatagc ttgctcttct
     1681 tgaccaagtg agaaggtttc acagttttct tgcccaccga agttatcaag tgataaccaa
     1741 gtctgtggag ctgtattgtc ctgccagata acagtaggaa gttgaaagtc tgtttcctgt
     1801 cctagtaatt tcttggtcaa taaggcattt atggactcac ggaagtcaat tgattgccaa
     1861 ttgttcatgt aaacatgagc accattatgg aaaaagagat gcttgtgtat atgagtagga
     1921 agagcatgga acatctggta aacatgaagt ggtttgacat tccaatcctg agaaccatga
     1981 gtaaagacaa cctctgcctt tactttatgg gcattgagca gataattgcg gtcatgccaa
     2041 aactgattgt agtccccagt ttttcggtct agctgagctt tcactttttc taagtcagct
     2101 tggtgagctt cattgccacg gatatagtcg ccagctaaga gattacgaga ataggttaac
     2161 tcagcaaggg agtcaaagtc ctcacctgga taaccacctg ggctagtcac cagaccgttt
     2221 tcacggtagt agttgtacca tgatgaaatt cctgcctcgg caatgataac ttctaaacca
     2281 tcgactcctg tagtcgcaag accattggac atggtaccta gataggaaag tcccgttgta
     2341 gcaacttttc cgtttgacca atcagccttg acttgacgct ggcgcgtgtg atcagtaaag
     2401 gcacggcaac ggtcgttaag ccaatcgatg acatttttat aagcctcgat ttgctggtag
     2461 tctccattag tcatgaaacc tgtcgagtct ttggtaccaa cacctgagac atagagagtg
     2521 gcaaagcctc tcggaaggaa gtagtcgttt agtgtatagc tagagttgat gtgagttagc
     2581 ttttcctcag cctctgctac aagctcagct ttaccttggg gttggacgag atttagttga
     2641 ggtttctcta gctcaatctt gtgaggaaga gaaacctcaa gctcgccctc catcttgtag
     2701 agagccttgt cactagcctt atcattggtt ccctgatgat aagggctggc tgtcatgatg
     2761 gcagggattt ttccatcaaa acgagggcga ataatgctaa cctttactag gtctggtagc
     2821 cctttttggt cagtatcgac acgagactca acgtaaacga cttcacgaat gacatcctgg
     2881 ctagaaaaag tagccaaact cttgccgtta aagtagtggt agtcattatc ctccggaata
     2941 agaccatcac taacaagttg gtcgataaga gtatttcctt ttttggtgcg agtattgagt
     3001 aactgataga gattttcaat caagtcacca tatataatgg gaaatccagt ttctttacga
     3061 aaaacgtcac tatcttcgaa gtcaaccaaa taagaaaagc ctaaaagttg aaaagcaaca
     3121 gtataaaaaa tatctgctgt cagttcattt tccgattgaa aaaatgtcag caggtctgtt
     3181 tttttatcag ctgctaggat ggaaagtggg tagttggtgt cttgataagt gaaaaagaaa
     3241 cgacgtaaaa aggtttcaag tgagtctttg tgattggctg tattttgtaa atcaaagcca
     3301 cattttttta gttcagataa gatattttct tttggaaaat tgatataact atattgatta
     3361 aaacgcatag aacctccata tagaatgaca gttaaggtta ttatatcaaa aaaaaagcag
     3421 aaagggaatt gttaacttca aaaggaaata atccaataaa aatgaataaa gtactaaatt
     3481 cagtat
//
LOCUS       DAVLTG010000098         3197 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLTG010000098 DAVLTG010000000
VERSION     DAVLTG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3197
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.099"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..201
                     /locus_tag="VYN12_002017"
     CDS             <1..201
                     /locus_tag="VYN12_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416315.1"
                     /translation="RLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSVLL
                     LFSNFSVPFIKAKEYELFKNSK"
     gene            1334..1573
                     /locus_tag="VYN12_002018"
     CDS             1334..1573
                     /locus_tag="VYN12_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416316.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1558..1836
                     /locus_tag="VYN12_002019"
     CDS             1558..1836
                     /locus_tag="VYN12_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416317.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            2125..>3197
                     /locus_tag="VYN12_002020"
     CDS             2125..>3197
                     /locus_tag="VYN12_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1416318.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPAPKPAPAPAPTPEAPAP"
BASE COUNT         1166 a          446 c          630 g          955 t
ORIGIN      
        1 agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt cgcattggat
       61 gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg ctatttgttt
      121 tcggttttac ttcttttttc taatttttca gttccattta tcaaagcaaa ggaatacgaa
      181 ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc ttaaaatcag
      241 atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac agtcgaggat
      301 cacttgttag gattacattt taatcatgct taataagaat ggagaattcc tatggggatt
      361 gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctgtt ctagctttag
      421 aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcctg gaaacattta
      481 ttttatagca attctaggct tagaattgct catatatatg tatttgagct gctcgatagt
      541 taggacagct ctattctgag aaatctgagc tatcaatgct tcagaatagt atttcgcaaa
      601 tggtttttat tgaagaggtg attgttttat gatagtctaa aataaaactg atttaatgga
      661 gtaaatggag aatcgtcaca tgaaacattt ttttgcagga attggtgaga taaaacttgt
      721 tggctactta ttgtatatat gtgtaggact agcccttctt tttcatatat atgtcatagg
      781 ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat ttgtaagtat
      841 gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga cttgaactgt
      901 atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa agagtgagat
      961 atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacctaaaa gtaatatagt
     1021 agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat taatttgact
     1081 ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt taaaccgttc
     1141 ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt ggcagagcta
     1201 aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga gaagccgact
     1261 ctaatcaacc actttgggca gtagtgagaa ctgccccgtg cttttttatt ttgagaaaat
     1321 atggagtttg tcgttgaaat tacttgattg tattttggac tatcaagaaa gattcaatgg
     1381 aaaaacatgt caagtatcaa cgaattataa gtatttagag attttcaaag tgaatttttg
     1441 cttgactgat ttacatcatt tatttgactt atacaaaatc acacgagatt atgctagtca
     1501 aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa atatcctatg
     1561 tacaatgatg taatcgaaag gatatcttta tatgagttta tcggtgatat tttctattct
     1621 aaaataataa gttgttgcat cgtagctagg gatttatcta aaaatactat gaaattggac
     1681 gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg aagagacaaa
     1741 agcggagtat ttaaatcagt tactctacat tttacaagcg ctaagaaata tgctaaagtt
     1801 cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg cttaagcttg
     1861 cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat gtttttatag
     1921 gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa agtagtatct
     1981 ttatctattt tttggagtag aagcttatga tatagaaatt tgtaataaaa atgtaatata
     2041 aaacatttga caaatattta cggggggagt atacttaata taagtatagt ctaaaaatga
     2101 ctatcagaaa agaggtaaat ttagatgaat aagaaaaaaa tgattttaac aagtctagcc
     2161 agcgtcgcta tcttaggggc tggttttgtt gcgtctcagc ctactgttgt aagagcagaa
     2221 gaagctcccg tagctaagca gtctcaagct gagagagact atgatgcagc aatgaaaaaa
     2281 tctgaagctg ctaagaaaga atacgaagaa gctaagaaag atttagaaga agcaaaagct
     2341 gctcagaaaa aatatgaaga cgatcaaaag aaaactgaag agaaagcaaa gcttgttcaa
     2401 aaagcggatg aagagcgtca aaaagcgaat gtggcagttc aaaaggcgta tttaaaactc
     2461 cgagaagcac aagaacaatt gaacaaaagt ccaaacaata agaaaaatgc cgctcaacag
     2521 aaattaaaag atgcattagc tcatattgat gaggtaacat taaaacaaaa agaggcggaa
     2581 gcgaatttca ataaggaaca agcaaaagta gttcctgaag cagataagtt agctgagact
     2641 aagaaaaaag cagaacaggc tgaaaaaaaa gaaccagaac ttgctaaaaa agtagcagaa
     2701 gctaaagcaa aagcagaaga agctgagaaa aaagctgttg aagccaaaca aaaagtggat
     2761 gctgaaaaat atgctcttga agctaaaatc gctgagttgg aatatgaagt tcagggacta
     2821 gaaaaagagc tcaaagagat tgatgagtct gactcagaag attatattaa agaaggtctc
     2881 cgtgctcctc ttcaatctaa attggatgcc aaaaaagcta aactatcaaa acttgaagag
     2941 ttgagtgata agattgatga gttagacgct gaaattgcaa aacttgaaaa agatgtagaa
     3001 gatttcaaaa actcagacgg tgagcaagct gaacaatatc ttgttgcagc taaaaaagac
     3061 ttagatgcta aaaaagctga attagaaaat actgaagctg accttaagaa agcagttgat
     3121 gagccagaaa ctccagctcc ggctccggct cctaaaccag ccccagctcc agctccaact
     3181 ccagaagccc cagctcc
//
LOCUS       DAVLTG010000099         3147 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLTG010000099 DAVLTG010000000
VERSION     DAVLTG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.100"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            292..1578
                     /locus_tag="VYN12_002021"
     CDS             292..1578
                     /locus_tag="VYN12_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1416319.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1593..1904
                     /locus_tag="VYN12_002022"
     CDS             1593..1904
                     /locus_tag="VYN12_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416320.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2153..2392
                     /locus_tag="VYN12_002023"
     CDS             2153..2392
                     /locus_tag="VYN12_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1416321.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            2413..2883
                     /locus_tag="VYN12_002024"
     CDS             2413..2883
                     /locus_tag="VYN12_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEV1416322.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HDAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          980 a          548 c          681 g          938 t
ORIGIN      
        1 tagactgtat caatcctttt ccattatagg agcaacagag tgggagtagt catctaagga
       61 ctaatttatg tatttttacg agtcagtatc tttggatact ggtttttact tttctagact
      121 ttttgactac ttgttaaaac tgggataatt ttcgactgtt taacagttat tatgcaaagt
      181 ctaaaagatt agaattgtca aaacaatccg tctaggcttg attttatcct ttatttacta
      241 taaaatgaga aggaaaaatg tcaaactttt atattgcaaa taggagaaat catgacaaaa
      301 acattaaaac gtcctgaggt tttatcacct gcagggactt tagagaagct aaaggtagct
      361 gttcagtatg gagcagatgc tgtctttatc ggtggtcagg cctatggtct tcgtagccgt
      421 gcgggaaact ttactttcga acagatggaa gaaggcgtgc agtttgcggc caagtatggt
      481 gccaaggtct atgtagcggc taatatggtt atgcacgaag gaaatgaagc tggtgctggt
      541 gagtggttcc gtaaactgcg tgatatcggg attgcagcag ttatcgtatc tgacccagcc
      601 ttgattatga ttgcagcgac tgaagcacca ggccttgaaa tccacctttc tacccaagcc
      661 agtgccacta actatgaaac ccttgagttc tggaaagagc taggcttgac tcgtgtcgtt
      721 ttagcgcgtg aggtttcaat ggaagaatta gctgagatcc gcaaacgtac agatgttgaa
      781 attgaagcct ttgtccatgg agctatgtgt atttcatact ctggacgttg tactctttca
      841 aaccacatga gtatgcgtga tgccaaccgt ggtggatgtt ctcagtcatg ccgttggaaa
      901 tacgaccttt acgatatgcc atttgggaaa gaacgtaaga gtttgcaggg tgagattcca
      961 gaagaatttt caatgtcagc cgttgacatg tctatgattg accacattcc agatatgatt
     1021 gaaaatggtg tggacagtct aaaaatcgaa ggacgtatga agtctattca ctacgtatca
     1081 acagtaacca actgctacaa ggcggctgtg gatgcctatc ttgaaagtcc tgaaaagttt
     1141 gaagctatca aacaagactt agtggacgag atgtggaagg ttgcccaacg tgaattggca
     1201 acaggtttct actacggtat accatctgaa aatgagcagt tgtttggtgc tcgccgtaaa
     1261 atccctgagt acaagtttgt cgctgaagtg gtttcttatg atgatgcgac acaaacagca
     1321 accattcgtc aacgaaacgt cattaacgaa ggggaccaag ttgagtttta tggtccaggt
     1381 ttccgtcatt ttgaaaccta tattgaagat ttgcatgatg ccaaaggcaa taaaatcgac
     1441 cgcgctccaa atccaatgga actattgact attaaagtcc cacaacccgt tcaagctgga
     1501 gacatggttc gtgcattaaa agaaggactc atcaattttt ataaggaaga tggaaccagc
     1561 gtcacagttc gagcttaaga aaggaaaagg aaatgataga ggcacagggt ttcttagtgg
     1621 ataagcaaac aagatgcatt cattaccata gcaagctgga tattattgct ttacaatgct
     1681 atgattgtaa aaagtattat gcttgttatc ggtgtcatga ttcattagaa aatcaccctt
     1741 ttgagccgta tcccttatct ttgatacagg ataagcctat tttatgtggt gtttgtctaa
     1801 aactactaac atataagcaa tataaagaaa gtttaagttg ccccttttgt ttttctcgct
     1861 ttaatccagg ttgccaaaat cataaggaac gctattttaa atagcaaatc atctagtttt
     1921 gaagtaggag aaaactcaat ttcaagagaa aatgaagtaa atcttcccac aataaaacgc
     1981 ataatatcaa gattgttcaa tacctgatac tatgcgtttt taagatttta aagacttttt
     2041 tcctttatct ggtattttga ctacttgtta aaactggggt aattttcgac tgtttaacag
     2101 ttattatgca aagtctaaaa gattagaatt gtcaaaacaa tccgtctaga gtatgcgtga
     2161 tgccaaccgt ggtggatgtt ctcagtcatg ccgttggaaa tacgaccttt acgatatgcc
     2221 atttgggaaa gaacgtaaga gtttgcaggg tgagattcca gaagaatttt caatgtcagc
     2281 cgttgacatg tctatgattg accacattcc agatatgatt gaaaatggtg tggacaatct
     2341 aaaaatcgaa ggacgtatgg agtggagtct attcactacg tatcaacagt aaccaactgc
     2401 tacaaggcgg ctgtggatgc ctatcttgaa agtcctgaaa agtttgaagc tatcaaacaa
     2461 gacttggtgg acgagatgtg gaaggttgcc caacgtgaac tggctacagg attttactat
     2521 ggtataccat ctgaaaatga gcagttgttt ggtgctcgtc gtaaaattcc tgagtacaag
     2581 tttgtcgctg aagtgatttc ttatgatgat gcgacacaaa cagcaaccat tcgtcaacgg
     2641 aacgtcatta acgaagggga ccaagttgag ttttatggtc caggtttccg tcattttgaa
     2701 acctatattg aagatttgca tgatgccaaa ggcaataaaa tcgaccgcgc tccaaatcca
     2761 atggaactat tgactattaa agtcccacaa cctgttcaag ctggagacat ggttcgagct
     2821 cttaaagagg ggcttatcaa tctttataag gaagatggaa ccagcgtcac agttcgtgct
     2881 taatgtagtt gtttagtttt aaaaaattat gcaaagctcc atatacaaca cttaaacgag
     2941 attaaagaat ggcgaaatcc cttgatgcgc aagagattag ctgtcttttt tattttttaa
     3001 gtgataaagt cggagctcag gtatcaaagc ctatcaaatt aaacaaagaa gtgatgtctt
     3061 agatattttg aaaaaaatta ataagcagaa aactctctat tattttgttg tagagagttt
     3121 tttgttaata aaatttcaca aaatgac
//
LOCUS       DAVLTG010000100         3117 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLTG010000100 DAVLTG010000000
VERSION     DAVLTG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.101"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            13..733
                     /locus_tag="VYN12_002025"
                     /pseudo
     CDS             13..733
                     /locus_tag="VYN12_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            782..1240
                     /locus_tag="VYN12_002026"
                     /pseudo
     CDS             782..1240
                     /locus_tag="VYN12_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
     gene            complement(1262..2215)
                     /locus_tag="VYN12_002027"
     CDS             complement(1262..2215)
                     /locus_tag="VYN12_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV1416323.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     misc_binding    2547..2776
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2936..3016
                     /locus_tag="VYN12_002028"
                     /pseudo
     CDS             2936..3016
                     /locus_tag="VYN12_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT          962 a          578 c          616 g          961 t
ORIGIN      
        1 acttttgaag agatgttagc tgtattaaaa acagcttatc aacttaaaca cgcaaaaggt
       61 ggacgaaaac ctaaattaag cctagaagac cttcttatgg ccactcttca atagtgcgag
      121 aatatcgaac ttatgaacaa attgcggctg attttggtat tcacgaaagc aactttatcc
      181 gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg tgttacggtt tcaagaactc
      241 ctctcagctc tgaggacacg gtaatgattg atgcgacgga agtacaaatc aatcgcccta
      301 aaaaagaatt agcgaatgat tctggtaaaa agaaatgcca cgctatgaag gctcaagcga
      361 ttgtcacaag tcaagggaga ttgtttcttt ggatatcact gtgaactatt gtcatgatat
      421 gaagttgttc aaaatgagtc gcagaaatat cggacaagct ggtaaaatct tggctgacag
      481 tggttatcaa gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa
      541 actcaagccg ctaacagttg aagataaaac ctataaccat gcgctatcta aggagagaag
      601 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg
      661 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
      721 actaggattc tagttttgca ggaagtctaa taaagaaact agcaaggtca ggccttactt
      781 tattggtgga catccaggat ttaattgtcc tctacttgat gatgaagtct atgaagatta
      841 ttatctagag tttgagaaag aagagacttg ctctgttcca cgtcctttcc cagaaacagg
      901 tatgttggat ttccaagata gaagtccatg gctagaggga caaaaagaaa tagatcttag
      961 ttatgatctt ttcagcaaag atgcagtgac tttggatgaa ttgcaatctc gaacaattgc
     1021 ccttcgttct cttaaacatg ataggggatt gaaagtgcat tttgcagaat ttccaaacct
     1081 catcatctgg tcaactttga acaagggacc tttcattacc tttgaaccat ggtctggctt
     1141 gtcaacattc cttgaagaag gagatcattt agaagataag aagaatgttt gtctcttaga
     1201 agccaatcag gttgaagaat tagggtttga gatagaagtt ttcccaaatt tcaagttgaa
     1261 gttagccacc caaaagaaat tcacttggcg acttgtagtc caagcatttt ttagggtagt
     1321 tgttaatcca attttcgata aaagctactt ctttcggagt cgttttcttg gttcctttag
     1381 gtaaccatct ccgaattaat cgattatgat tttcatttga acctctctcc catgaagagt
     1441 aagcatgtgc gtagtagata tgttcctcag gaaatacctc agacaatcgt ttgaactccg
     1501 aaccattatc tgcagtaatg gacagaatac gatgctcccc taatagtaac gtaagcgcct
     1561 gattgacaga ttcagcagtt ttatttggaa ttaaccttat aatttggtgt ctgctccgcc
     1621 ggtcggttaa gactaacagg caataatttt ttatcttagt cagtaggacg gtatcaattt
     1681 cataatgacc attttccaag cgaagattaa taacgtcagg acgttcttcg atagatttac
     1741 ctgccggctt aaagttcgga ctagcttgct tcttgacacc tttccttttt ctgggataaa
     1801 gcatgtcggc cttcgtcaat cctaaatgac cattatgaaa ccagtagtag atggttgaaa
     1861 taccaacttt cacttgcttc ttgttaacca tcatttcagg cgaaaatttt tgcttatgat
     1921 agtgtaagat cttctctctg atttcctttg ttaaaattaa ctttttcacc gaccgttttc
     1981 gattgaattg gtaaacagtt tgtgcgtaat cggcagaata gacctttttg tatagccctt
     2041 ttctcacttg ttgtaaagtt gtacctcttt tgacttcagt atgaatcgtt tgaggcgcct
     2101 ttcctaacaa gcctgcaatt tcacgattgg acttattttc attcttccac cgctcaatca
     2161 agcgacggtt atctattgtc aaatgtttcc cttttggggt ataatgttct tgcatctctg
     2221 tgcctttcct tgtgtttgtg gtgaacaaca agtatagcac agaggtgttt tcttatacct
     2281 taaatcacat ttcatttgac aacaggaacc cttgaacctg ttttttcagc taaaccaagg
     2341 ctatgattag ccttggccac ctagcctaac agtttcaaac ctgttatcaa atgaaatcat
     2401 caacttactc aaacatagtg aaacatctaa ttcttgacta aggtaaggtg gctaacttca
     2461 ttatagaact ttcaatggtc acattcgaat gatattttca aaaaaatcgt aaaaaagtct
     2521 tgacaaagaa aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt aactattttt
     2581 gatcttcagg gagcctgtgg tggttgtgaa taggtggttg gaagtagtga aagtgggctg
     2641 attttgaaaa tgaatttgaa acaatgaaaa ttcggtgcgc acaccttaca gtgcagcttg
     2701 ttgttaaaca aggcagagat gtaaagggat agtcccttta taattgaggt ggcaccgcgt
     2761 taccaacgcc ctcacacgga agtatattct gtgtgtgggc ttttttctat ccgtcgtttg
     2821 gtttatcttt tattagggcc ttaagtcgct ttgatgaact tgagttctat ctacagctcc
     2881 tttcctccta ctaaaagcaa acaaaaagct ggactaatac gaaaaaagct agtgatactc
     2941 aatgaaaatc aaagaacaaa ctaggaaact atccgcaggt tgctcaaaac actgttttga
     3001 ggttgtggat aaaactgacg aagtcagctc aaaatactgt tttgaggttg tggataaaac
     3061 tgacgaagtc agctcaaaat actgttttga ggttgtggat aaaactgacg aagtcag
//
LOCUS       DAVLTG010000101         3106 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLTG010000101 DAVLTG010000000
VERSION     DAVLTG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.102"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..3087)
                     /locus_tag="VYN12_002029"
     CDS             complement(<1..3087)
                     /locus_tag="VYN12_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1416324.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVG"
BASE COUNT          792 a          644 c          487 g         1183 t
ORIGIN      
        1 tcctactaat attccatgga atacattatt cacataactt tcttgaccat ctggaagttc
       61 aacttcacga gcatccatag ttgctcctaa acggaatgtg ccattaggat tgctattcat
      121 tgcatctact aaatttttaa atgatgtata taccccagtt tcactttgct gagtttttgg
      181 taaatagtat gtataatttt ctagtacatt attattttca tgttgtatca gactatttgc
      241 acttgctact atcttataaa catctctatt atctttagta tcattagtaa tgcttgtaac
      301 tggtagcatc acatctttaa agttctctga tttaactttc ataaagtaat tttctgcatt
      361 acttggtaaa gaagcaagtg aagttacatg tcgatactta ttaccatctt ttgaatatag
      421 ttctacagaa gatatatttc taagttctaa tttcttaata acttcttttt catctttagc
      481 gtcatctttt ttctcatctt tatgacgata aagttcatcg tatactggtg gaatttcatt
      541 acctgctata atactcttaa tccaagctaa ttgtgtagga gataaaatca atccgcctga
      601 gcgattttgt gctccatttt gatgcacacc aataacttca ccattagcat taaatattcc
      661 tccaccactc ataccaggat ttccaccttg atattgaaca ccgtaggtgt tattcgcata
      721 ttcttgttcc atttctaccg tagcatcttt taagtgcgta tatttcccag ctggatatcc
      781 atgaacattt agtttgtcat taagatttac tttcgaataa tttttaacta attctacatg
      841 ttctctgcca gttgtttcag gtagcttaat cactgctaaa tcatagataa atccttttgg
      901 ataatctttt ttattataaa aatgaatatt gttagcagta aatgttcctt tttgtccatc
      961 aggagtcacc cactcatata cgtttttaga tttatcacct ctaaattcgc cagtagtatt
     1021 atcagtagaa ttattaatga aattatgtgc tactgttaaa agtacatttg gtgcaataaa
     1081 agtagctgat cctactccag taaccttcga cgaatctgta ataaagttca tattaattaa
     1141 tgcactagat tttttctgaa tactcatttc ttctggtgta ttagtatttt cattatttgg
     1201 tttagtatct tctgcactag gttgttcgat tttaccagta tattctttca gtgcttctac
     1261 tttctctggc tcgactatcg ctccggcttg cacccctgtg tattctggta gtggtgctat
     1321 ctgctctggt tcaacaatag cgccagcctg cacccctgtg tattcttttg atggttctac
     1381 tttttctggt tctactattg ctccggcttg cactcctgtg tattccttcg gtgcttctac
     1441 cttctctggt tcgactatcg ctccagcctg cactcctgtg tattccttcg gtgcttctac
     1501 tttctctggc tcgactatcg ctccggcttg cacccctgtg tattctggta gtggtgctac
     1561 ctgctctggt tcaacaatag cgccagcttg tactccagca tattccggtt caactttttc
     1621 aggttcaaca atagctccag cttgtactcc tgtatattct ggtagcggtt ctacctgctc
     1681 tggatcaccc ttgtcagtca tgactgcctc tggtaacgct ggttgaactt ctggtacgcc
     1741 tttatcactt actacagctt ctggcaactc tggttggact gctgactcac ctttgtcggt
     1801 taatacagct gctggtagtt caggctgaat tgcgggttca acaatagctc cagactgtac
     1861 ttccttatgt tctgcaccag tctcagcttg ttcctttata acttgagctt ttttagtacc
     1921 tttttcgact attcttgaaa caggcgcagt cgttgaagtt gaaataattt ctcgtgaaac
     1981 ttcttcattg tttacagaaa atattctgac gatttcaact ttcttaccta atgcaccttc
     2041 ttgttttact cttacagttc cttctgctaa atcaggattt tcttgaattt cttcttgaaa
     2101 atctattttt gtttctatag tttcgtcacg atataagagt tccggtttgt tcaactgacc
     2161 tgatagcact tcatcctgtg gatttaatgt atttacccca gtcttttcct ttggagaaat
     2221 cttctcctct ttcttcgttt ctagattctt atgttcggct aattgttctt gagaatctga
     2281 agattgtttc tcttcttttc ttggattgat taattcagta gagaaaggtt tttcaactac
     2341 ttgaacttct gtcggcttag ttgaagaaac aggtgtttgt tcctgaatag cttgtactgt
     2401 tgatggatgg tctacaaaat ttggtgtaac attataatcc accttttgtt gttttgtagg
     2461 agtggctgct gatttttctt gattacttac ttcaaaatca gaagtcgttt ttccctcttt
     2521 gatatatcca atataagtgt aacctgaaat ctctttagga agaggtaatt tttctccaga
     2581 ggtcaattca tagtccgtat tgtaatttag caaaagatga ttttctaaag catggactga
     2641 aactaagaca ccatttccca ttcccgcaac caatactaaa tgtaataccg ttttattctt
     2701 aacctttttc ttggaaacag caaaaattaa aattcccaga gcagctaagc tagcaccagc
     2761 aactagggct tgcctctcat tcttgcttcc agtatttggt aattccgcca gttgattttg
     2821 agaatttaac ttataaacaa gataataagt ttcatcatca ttctccacgt atgtcggaat
     2881 atcatagaca agctgcttct tttcttctga tgatagctct gaatctgcca catatttata
     2941 gtgaactccc gcagtttctt gagcatccac agatgaacta gctaatacag acataaaaaa
     3001 taaacttgaa atcgttgcag atacaagtcc tactgataat tttctaaatg aaaaacgctc
     3061 ttgtttttca ccaaaatact tttccattat tcctccttga aataaa
//
LOCUS       DAVLTG010000102         2976 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLTG010000102 DAVLTG010000000
VERSION     DAVLTG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.103"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..381)
                     /locus_tag="VYN12_002030"
     CDS             complement(<1..381)
                     /locus_tag="VYN12_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416325.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKY"
     gene            complement(395..1108)
                     /locus_tag="VYN12_002031"
     CDS             complement(395..1108)
                     /locus_tag="VYN12_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1416326.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1566..1946)
                     /locus_tag="VYN12_002032"
     CDS             complement(1566..1946)
                     /locus_tag="VYN12_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1416327.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2368..>2976)
                     /locus_tag="VYN12_002033"
     CDS             complement(2368..>2976)
                     /locus_tag="VYN12_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1416328.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPSEEKPQTEKP
                     EEETPREEKPQSEKPESPKPTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDP
                     IIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          913 a          583 c          477 g         1003 t
ORIGIN      
        1 atattttgct acatgatcta ggtatatatc aaaaaagtca tgaggaaaat ctcccataca
       61 gccattacga ttcatattga ggctatattt tcgattagta agataattcg gaaatatatt
      121 tcctattact ctaagattat ctacttgtga atcccttctc ccaatataat ccccttcttt
      181 gactaatgat ggagatttcc aagtaaaaat taaatcgcca gagaaatttt tcttatcaaa
      241 aaacttaaaa agagattgat aaatactatt tgctaattga caagtgtcag atgtaaattc
      301 ataattaaca gcttcattaa aatcaacttc agacatttca atgtactctt caatagtaat
      361 attagctttt tttgtagtca ttagctcatc tcctttaaaa tgtgatcttt tcaagaatat
      421 ttttatctaa acaatccagc aagtcttggt aagaatagac ttcgtaagtc ggctgggctt
      481 gtgtgtgatt ttcgaggtga tgaggattat accagatagt gtcaatcccc gcattattgc
      541 caccttgaat gtcggcggtt agagaatctc caatcatcag cgtcttttct ttactaaatc
      601 cagcaatttg ctggccaatc ttttcataaa agagagcatc cggcttttga gtttgcaact
      661 gttctgagat aaagacttga ttgaaataag gtactagacc agattgagcc aaacgtcctg
      721 tctgaatggc agtaatgcca tttgtcgcag catacaagtc ataatcacgc tcaatgaggc
      781 tgtccaagag atcatgagcg cccgatagtg tttgtccctg ctgagcgaga taaaattggt
      841 aacgctgggc aagaaaacta ccgtcttttt cctgtccaaa atgagaaaat aaacgagaaa
      901 agcgcgtgtt aaccaactct tgtttactga ttttcttcag ctccaagtct ttccagagag
      961 ccttgttcat aggaacgtaa taatctttat aagcctgaat atccgcaact ccttcttctt
     1021 ttagaagttg ggtcaaagcc acatcctcag cagcatcaaa atcaagaaga gtgtggtcga
     1081 ggtcgaagag tagaaatttg tagaacaatt tgaggttttc ctttctgaaa attcattaag
     1141 aacattatat cataaagcac ctcatacaat taactaattt aatcacttaa aaaaattcga
     1201 acactttcta tacaactgac agctcaaatc tttcagaata gaacaatact aactatcgaa
     1261 caccccgtct tcataaatac atatgtaatt ctagacctag aattcctata aactaaatgc
     1321 tttcatactc ttccaagtaa ttgattgcct taaattttaa tttttgaagg attctaaagc
     1381 tagaatagcc ccatcacaat cagttttgat tgattcacaa tttagaaaca ctatagtttc
     1441 actcctgtta aaataaaaag gaactgcata aagcaatccc tttctgattt tgaaatcatt
     1501 tacttaacat tttatagttg agataatcaa tagcttatct ataaaaagag ttatagtaaa
     1561 attccttatt tattgatttc aagctccgct aactgtattt gaataactga cagttctgca
     1621 ccagcctgaa gaagagcagc tgcattatag gcaccttcta caattggaac cctgttgatg
     1681 atgatacttt tatcactgaa atcagtcacc atttttaagt tcattttagc agaacctagg
     1741 tcaaaaaagg caagtaaagt atctgctgga ttttcggaaa caaccctatc tacttgatca
     1801 aaactcgttc caattcctcc gccctcggtt cctcctacat aagtaatcgg aacatcttta
     1861 gctactttac taatcagttc aacaacacct tctgcaatat gtttggaatg tgaaacgata
     1921 acaagaccaa taccaatact ttccatcaaa ccactccagt ttctaaaata gcagtaaaga
     1981 gtaatcctga tgagaatgat ccaggatcaa tatgtccaag aaaccacatg ctcctaagac
     2041 aagagctaac agactggcca tcaataatag tattgttctt tttttcatca ttactcctta
     2101 actagtgttt aactgattaa ttagccagta aatagtttat ctttatttac actatctgtt
     2161 aagatatagt aaaatgaaat aagaacagga cagtcaaatc gatttctaac aatgttttag
     2221 aagtagaggt atactattct agtttcaatc tactatattt tgcacatttt catgaaaaaa
     2281 atgagaacta gaactcacat tctgctctca tttttcgttt tcccgttctc ctatcctgtt
     2341 tttaggagtt agaaaatgct gctaccttta cttactctcc tttaataaag ccaatagttt
     2401 ttcagcttct gccataatag tattgttgtc ctgggtgcca aatagtaaat tattttttaa
     2461 tcctgtgaga gtctctttgg cattggactt gataattgga tcctggattt ttccaagtaa
     2521 atcttcagcc tctctcagtt tttcttcaac cttttcagtc tcgacctgag gttcttctga
     2581 ttcctctggt gattcttctg gttcctctgt tggttttgga gactctggtt tctcgctttg
     2641 cggtttctct tctcgagggg tttcttcctc aggtttttct gtctgaggtt tctcctcgct
     2701 tggtttttcc gtttgattgg tatcagcttg accatttttg tttctttgaa catggtcgct
     2761 agcgttacca aaaccattat ctgaatgcgg acgttcgttt ggatgttcga catagtactt
     2821 gacagtcgcc aaaagatcct caagagtata ccccttaggt gcctcataaa ggccttcgtc
     2881 aaaccactca aatttgatgt tatggtaatg gtcataatga ggtatgatta aactaccgtt
     2941 tttgacttct acagtatatt gaagattgta aggcat
//
LOCUS       DAVLTG010000103         2929 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLTG010000103 DAVLTG010000000
VERSION     DAVLTG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.104"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(140..673)
                     /locus_tag="VYN12_002034"
     CDS             complement(140..673)
                     /locus_tag="VYN12_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1416329.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(762..1538)
                     /gene="recX"
                     /locus_tag="VYN12_002035"
     CDS             complement(762..1538)
                     /gene="recX"
                     /locus_tag="VYN12_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1416330.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1576..>2929
                     /gene="rlmD"
                     /locus_tag="VYN12_002036"
     CDS             1576..>2929
                     /gene="rlmD"
                     /locus_tag="VYN12_002036"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1416331.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          921 a          530 c          536 g          942 t
ORIGIN      
        1 tacgaattct gcataaatct ctttctagta atgtgttgta actctgctat aatggattta
       61 ttcctttttg tatttacaca atttatttta tactaccaaa aaaacaaggt caggattttg
      121 ttcctgacct ttgacaactt taccgattct ttagttctac atagcgcttg taccaaatgt
      181 ttacataggc ttctgagaaa ggaccacgtc cattgttaat ccaatcaaca agaattttga
      241 catgttcttt taaaatatag tccaagtcat cagaataatt cattttgcgt ttgtgacgct
      301 cgtattcttc aacgtccaag agacgttttt ccccatctgt aaaaatttta acatccaaat
      361 cgtaatcaat atacttcagt gcttcttcat ccagatagta ggggctagcc atattgcaat
      421 agtaagaagt tccattatca cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa
      481 agtaaacaat agccggttct cgagtgaccc aacgacgacc atcactttcg gtaacaagtg
      541 tatgatcgtt gacaccaata atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc
      601 aagttcggtg gagactccca tcatgcttat aactttgaat tgtaataaag tcgccttctt
      661 ttggaagctt cataactaac caactttcta caatttataa gtttatcatt tactattgta
      721 ccataaaatt acctaaaatc tgtgaatttc acttggaaat attaaagata ttctctaaga
      781 gcgcttgcta tatccgaaaa atcgtagccc tttcgtgcta aaacttgagt taaacgctgc
      841 ttcagttcgt atccttcata ctttcgagca tacttagtat attgcttatc aagttccttg
      901 aagatgagtt cttgagtcgt ttcttggtca acttggctat ctaagtcgtc aaaggcaatt
      961 ttagcatcag aataagagaa gcccttgtta gtcaagttct ggataatctt atcttgcagg
     1021 gcacgagctg gaagttttcc ctcatatttt ttcaatagtt tattggctac acgttgagca
     1081 acttcagaaa aatcaaattc tttcaagttc tcttctatag tagattttga aatccctttt
     1141 tgagatagtt tctgagtcag cacataagga cccttgtctc ctgaaagttg attggtattg
     1201 atgatagcat aagcgtactg accatcatta atccacttat cttctttaag attagcaata
     1261 acttgagaaa cgatgttttt atcaatatcg tattttttca gatattctct gacttctttt
     1321 tcagtgcgtg ctttaaagga taagtggtag agagcgagat tcttaccata agaaaattga
     1381 gcaaagtctt gaatctcttt caattcctct tcgcttatca ccttatctct cgataacata
     1441 aaacgaacaa ttgtatcttc ggtgatatag catttgtcgc cattatcaag ctccatcagg
     1501 tagagtcttt ttttcttttc aagttttgtg attttcatag ctctattata actcaaaatg
     1561 tgataagata ggggtatgaa tctgaaagtg aaacaaaaaa taccattaaa aatcaagcgc
     1621 atgggaatta acggtgaggg aatcggcttt taccaaaaaa cattagtctt tgtaccagga
     1681 gctctcaaag gcgaagatat ctattgtcag attacttcta ttagacgcaa ctttgttgaa
     1741 gcaaaattac tgaaggtcaa caagaagtct aaatttcgaa ttgtgccatc ttgtactatt
     1801 tataatgaat gcggaggctg ccaaatcatg cacctgcatt atgataagca gctggagttc
     1861 aagacggact tacttcatca agcgctgaaa aaatttgctc ctgcaggata tgaaaattat
     1921 gaaattcgtc caactattgg aatgcaggaa ccaaaatatt acagagctaa gttacaattt
     1981 cagactcgaa aatttaaaaa tcaggtcaag gcgggcttat atgcacaaaa ctctcactat
     2041 ttagtagagt tgaaagactg cctggtacaa gataaggaaa cccaagtgat tgctaatcgc
     2101 ttagcagaat tacttactta tcaccagatt ccaatcacgg atgagagaaa agttctaggt
     2161 gtccgtacta ttatggtccg acgcgcgaga aagaccggac aggttcagat tattattgtt
     2221 acaaaccgcc agcttaattt aactcaattg gtaaaagagt tggttaaaga tttcccagaa
     2281 gttgtgacag tagctgttaa tacaaataca gctaaaacca gtgagatata tggtgaaaag
     2341 acagagatta tctgggggca agagagtatt caagaaggtg tactcaatta tgaattttca
     2401 ctatcccctc gagcttttta tcaactaaat cctgagcaaa cagaagtcct ctatagcgaa
     2461 gcagtaaaag cgctggatgt tgataaagaa gaccatttga ttgacgctta ttgtggagtt
     2521 ggaacgattg gatttgcctt tgcaaagaaa gttaaaacac tcagaggtat ggatattatt
     2581 ccagaagcta ttgaagatgc caagcgaaat gctaaaagaa tgggatttga caatactcat
     2641 tatgaagctg gaacggcaga agagattatt cctcgttggt acaaggaagg ctaccgagca
     2701 gatgctttga ttgttgaccc accacgtaca ggtctggatg ataagttatt agatactatt
     2761 cttacttatg taccagaaaa aatggtttat atttcttgta atgtttcgac cttggctcgt
     2821 gatttggtac gcttagtaga agtctatgat cttcattata tccagtcggt cgatatgttc
     2881 ccacatacag ctcgaactga agctgttgta aaattaataa aaaaagttt
//
LOCUS       DAVLTG010000104         2617 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLTG010000104 DAVLTG010000000
VERSION     DAVLTG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.106"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            32..103
                     /locus_tag="VYN12_002037"
     tRNA            32..103
                     /locus_tag="VYN12_002037"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:64..66,aa:Gln,seq:ttg)
     gene            265..1467
                     /gene="rpsA"
                     /locus_tag="VYN12_002038"
     CDS             265..1467
                     /gene="rpsA"
                     /locus_tag="VYN12_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1416332.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1552..2617)
                     /locus_tag="VYN12_002039"
                     /pseudo
     CDS             complement(1552..2617)
                     /locus_tag="VYN12_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          795 a          441 c          596 g          785 t
ORIGIN      
        1 ggttcgaatc cctctctctc catttcatta atggggtata gccaagcggt aaggcaaggg
       61 actttgactc cctcatgcgt tggttcgaat ccagctaccc cagttcttag gtaataatca
      121 agataaaaag caaaatatct tagggtattt tatttttata attgaaagac gtgaatgata
      181 tgaacatgtc cttgcgggtg cttaggaaaa aaattataag tatgtcaagt ttaagaaaaa
      241 cttgattgtt ggaggatttt ttagatgaac gaatttgaag atttgctaaa tagcgttagt
      301 caagttgaga ctggtgatgt tgttagtgct gaagtattga cagttgatgc gactcaagct
      361 aacgttgcaa tctctggaac tggtgttgaa ggtgtcttga ctcttcgcga attgacaaac
      421 gatcgtgatg cagatatcaa tgactttgtt aaagtaggag aagtattgga tgttcttgta
      481 cttcgtcaag tagttggtaa agatactgat acagttacat accttgtatc taaaaaacgc
      541 cttgaagctc gcaaagcatg ggacaaactt gttggtcgcg aagaagaagt tgttactgtt
      601 aaaggaacgc gtgccgttaa aggtggactt tcagtagaat ttgaaggtgt tcgtggattt
      661 atcccagctt caatgttgga tactcgtttc gtacgtaacg ctgagcgttt tgtaggtcaa
      721 gaatttgata ctaaaatcaa agaagttaac gctaaagaaa accgcttcat cctttcacgt
      781 cgtgaagttg ttgaagcagc tactgcagca gctcgcgctg aagtattcgg taaattggct
      841 gttggtgatg ttgtaactgg taaagttgct cgtatcacaa gcttcggcgc tttcatcgac
      901 cttggtggtg ttgacggatt ggttcacttg actgaattgt cacatgaacg taacgtatca
      961 ccaaaatcag ttgtaactgt tggtgaagaa attgaagtga aaatccttga tcttaacgaa
     1021 gaagaaggac gtgtatcact ttcacttaaa gcaacagtac caggaccatg ggatggcgtt
     1081 gagcaaaaat tggctaaagg tgatgtagta gaaggaacag ttaaacgttt gactgacttc
     1141 ggtgcatttg ttgaagtatt gccaggtatc gatggacttg ttcacgtatc acaaatttca
     1201 cacaaacgga ttgaaaatcc aaaagaagct cttaaagttg gtcaagaagt tcaagttaaa
     1261 gttcttgaag ttaacgcaga tgcagaacgc gtgtcacttt ctattaaagc tcttgaagaa
     1321 cgtccagccc aagaagaagg acaaaaagaa gaaaaacgtg ctgctcgtcc acgtcgtcca
     1381 agacgtcaag aaaagcgtga tttcgaactt ccagaaacac aaacaggatt ttcaatggct
     1441 gatttgtttg gtgatatcga actttaatca aattgaaaat tcacaaaatc ctttgtttac
     1501 taaacaaggg atttttctgg ctctttgtca actgtagtgg gttgaagtca gctaagcttg
     1561 agaaaggaca aatttcgtcc tttctttttt gatgttcaaa gcgataaaaa tccgtttttt
     1621 gaagttttca aagtttcgaa aaccaaaggc attgcgcttg ataagtttga tgagattatt
     1681 ggtcgcttcc agtttggcat tagaatagtg tagttgaagg gcgttgataa tcttttcttt
     1741 atctttgagg aaggttttaa agacagtctg aaaaatagga tgagcctgct taagattgtc
     1801 ctcaataagt ccgaaaaatt tctctggttc cttattctgg aagtgaaaca gcaagagctg
     1861 atagagctga tagtggtgtt tcaagtcttc tgaatagctc aaaagcttgt ctaaaatctc
     1921 tttattggtt aaatgcatac gaaaagtagg acgataaaat cgcttatcac tcagtttacg
     1981 gctatcctgt tgtatgagct tccagtagcg cttgatagcc ttgtattcat gggattttcg
     2041 atgaaactga ttcatgattt gaacacgcac acgactcata gcacggctaa gatgttgcac
     2101 aatgtgaaag cgatcaagaa cgattttagc attcgggagt gaaacagtct gggagactgt
     2161 ttcagcctga gcctagaaat ttgaaagcga agctgtttag ccaagtcata gtaagggcta
     2221 aacatatcca tagtaataat tttgacgcga catcggacag ctctatcgta gcgaagaaag
     2281 tgatttcgaa tgatagcttg tgttcttccc tcaagaacag tgatgatatt gagattgtta
     2341 aaatcttgcg caatgaagct catctccatc tcccgattga aacagtcact ccccggactg
     2401 tttcaacgtc ccaggacata atctcaggaa gacgcgaaaa atcatgctca aagtgagaat
     2461 cattgagctt gcgaatgaca gttgaagttg agatggaaag ctgatgggca atatcagtca
     2521 tagaaatctt ttcaattaac ttttgagcaa ttttttggtt gatgatacga gggatttggt
     2581 gatttttctt taccagggga gtctcagcaa ccatcat
//
LOCUS       DAVLTG010000105         2479 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLTG010000105 DAVLTG010000000
VERSION     DAVLTG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2479
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.107"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            108..1115
                     /locus_tag="VYN12_002040"
     CDS             108..1115
                     /locus_tag="VYN12_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1416333.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQNRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            1118..1318
                     /locus_tag="VYN12_002041"
     CDS             1118..1318
                     /locus_tag="VYN12_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1416334.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            1470..1652
                     /gene="rpmF"
                     /locus_tag="VYN12_002042"
     CDS             1470..1652
                     /gene="rpmF"
                     /locus_tag="VYN12_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1416335.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            1668..1817
                     /gene="rpmG"
                     /locus_tag="VYN12_002043"
     CDS             1668..1817
                     /gene="rpmG"
                     /locus_tag="VYN12_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1416336.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2297..>2479)
                     /locus_tag="VYN12_002044"
     CDS             complement(2297..>2479)
                     /locus_tag="VYN12_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416337.1"
                     /translation="ATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNT
                     TTPDGYRVNANGEWVG"
BASE COUNT          820 a          476 c          452 g          731 t
ORIGIN      
        1 aagaaattat tgggctgaaa gtttttagtg attatttttc aactttctat tgacttttaa
       61 aaacaaagtg atatcattta gatatcaaat aatgggaggt cattcttatg actgaaaaac
      121 taatcaattc aaaaccaaat ggtgtattcg cattgattct cattgaattg acgctcgtac
      181 ttggtatctt tatatttata atgggtgttg gttcggaaaa catttttgga attattatcg
      241 gacctttact aatcgtaatt gcaggtctag ctcatgctgg tttaaaagtt gtcaaacctc
      301 aggaagctct ggttctgaca ctctttggta attatacagg taccatcaaa gaacctggtt
      361 tttactttgt caatcccttc agcgtagcag tcaaccctgc aaaccacact cgacttggac
      421 aaagtggtga tgttagcaca aaatctcctt ttttaggtgc taaatcatca aatgacaatg
      481 atgtaaatct tgaaattggc aagaaacaca tttccctcaa agtcatgacc ttgagcaatt
      541 ctcgtcaaaa aatcaatgat tgcttaggaa accctgtaga aatcggtatc gcggtaactt
      601 ggagagttgt cgataccgct aaggcagtct tcaacgttga taactacaaa gaatatcttt
      661 cattgcaatg tgatagcgcc ctccgtaata ttgtccgcat ctatccttac gatgtgtctc
      721 ctaatgtgga tactacgggt gacgggcaag cagatgaagg tagtctccgt ggctctagcg
      781 aaattgttgc taaccgtatt cgtgaagaaa tccaaaatcg tgttgaggat gctggcttgg
      841 aaatccttga agcacgtatc acttacctag cttatgctcc agaaattgct gccgttatgc
      901 ttcaacgcca acaagcatct gccattattg atgcacggaa gatgattgta gatggtgctg
      961 taggaatggt tgaaatggca ctagaacggc tcaatgaagg ggaattggta gaacttgacg
     1021 aagaacgaaa agctgccatg gtttcaaatc tccttgtcgt tctttgtggc aatcatgatg
     1081 cacaaccaat tgtcaacaca ggaagtcttt actaaagatg gctgaagcta aaaaaaagca
     1141 gatccccctt cgactctcaa caaagttata cgctgcactc gcatcatggg cagaagacga
     1201 ctttcgttca gtcaatgggc aaatcgaata tctcctcaca gagtgtgtca agcaacggaa
     1261 gaaagacgga aaatacgtat cagaaaccat tgacgaacca tttgagattg atatttaaca
     1321 ccttctcctg tctgccgtgt cggataggag aattttttca tctttttttg tcaagtaact
     1381 ttactttaca aaaaaaatgt gttatcctag tatggttgat gaaaatcagt agattgaatc
     1441 gaatataaat acctaaagga gaaatcaaaa tggcagtacc tgcacgtcgc acttcaaaag
     1501 cgaagaaaaa caaacgtcgt acacactaca aagtaacagc tccatctgta aactttgacg
     1561 aaactactgg agattactca cgttctcacc gtgtatcact taaaggatac tacaaaggac
     1621 gtaaaatcgc taaagctgca tcagctgaat aatagaaggg agataccatg cgcgtaaata
     1681 ttacacttga acacaaagaa tctggtgaac gcttgtacct tacttctaaa aacaaacgta
     1741 acactccaga ccgccttcaa ttgaagaaat actcaccaaa acttcgcaaa cacgttgtgt
     1801 ttacagaagt gaagtaagca ttcaatacga atcaatacag aagaaaaacg cttgatcagc
     1861 gttttttctt tttgttaatt tcactatatt gcaagagaaa tcattcgaat gactacattt
     1921 tttgaaataa gaatacggat tcggacaatt aaaagcaaga ggaactcaaa tgtaagttgg
     1981 ggttcctttt ttgtatattt ttcaaataac gcctctacac tatttgtagc aaattcacca
     2041 actacagttg tatcttagtt aaaataagtt agaatatgta agtgagtacc agatatacca
     2101 agacatcgtc accatctaag gtatattcaa aatacaaaag ttgaccaact agatttctga
     2161 atatccttat atatccattc ttaaaattgg tttaaatagc gtagtctttt aaactagttt
     2221 taagaatcca aaaaatcttc ctacatatgt aagaagattt tttagttcag aatgattaga
     2281 tttagctaat ggatacctat cctacccact caccgttagc attgactcga tagccatcgg
     2341 gtgtagtcgt gtttactaat aaatctcctg aattataggt atagtaccat ttaccagaaa
     2401 ctgtaaacca accagtagcc attgaacctg attcatttaa gtaataccat aagcctttgt
     2461 ctttaaccca accagtagc
//
LOCUS       DAVLTG010000106         2276 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLTG010000106 DAVLTG010000000
VERSION     DAVLTG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.108"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            4..1758
                     /locus_tag="VYN12_002045"
     CDS             4..1758
                     /locus_tag="VYN12_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416338.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1724..>2276
                     /locus_tag="VYN12_002046"
     CDS             1724..>2276
                     /locus_tag="VYN12_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416339.1"
                     /translation="MNGGFQMKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAI
                     LLMIFAQEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTA
                     ENLSKLPLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAG
                     NVKMGLAVIIPSILSFIFIPLSKK"
BASE COUNT          792 a          315 c          421 g          748 t
ORIGIN      
        1 cttatgaaga tttacaaaaa actatttgct tatgtccaag ataagaaata tcttggggtt
       61 ttggccataa ttttttctgc tatatctgct gcacttacag tatatggata ttatttaatc
      121 tacaaatttc tagataagtt aataattaat tcaaacttat ccggtgcaga gagtatagca
      181 ttaaaatctg ttattacact aacaagtgga gcgatatttt attttgtctc aggaatgttt
      241 tcacatatct tgggatttag gcttgaaaca aatttaagaa aaaggggaat cgatggtctg
      301 gaaaaagcaa gttttaggtt ctttgactta aatccatctg gtcaaataag aaagatcata
      361 gatgataatg cagcacaaac tcatcaggtg gtagcacaca tgattcccga tagttctcag
      421 gcaataatca cacccgtact tgtacttgca cttggcttta tagtaagtat aagggttggc
      481 ataattttgc ttgctcttac tataattggt ggcttaattt taggggcaat gatgggcgag
      541 caagaattta tgaagatata ccaagaatcc ctatctaaac taagtgctga aactgttgag
      601 tacgtgagag gaatgcaagt tgtaaaaata tttaaagcaa atgtagagtc ttttaaaagc
      661 ttttataagg cgataaaaga ttactcaaag tatgcttatg attattccct atcttgtaaa
      721 aggccttatg ttttgtatca atggttattt tttggactga ttgcaatttt aattattcct
      781 atagtttatt ttatgactag cttagctagc gcaaaggtga ttttacttga gcttatcatg
      841 attttatttt tatcaggagt tctctttgtt tcattcatga gaatgatgtg gtactccatg
      901 tatatttctc aaggaaatta tgcagtagat actttagagg cgctttacga agatatgcaa
      961 aaagacaaat tagtgcatgg taatgtcaat aattttaaaa actataatat agaatttgag
     1021 aatgttagct ttgcttataa tgataaagct gtcattgaaa atttatcctt taatttagaa
     1081 gaaggaaagt cctacgcact tgtcggttca tctggatcag gcaaatcaac agtagcaaaa
     1141 cttatatcag gtttttacaa tgttaataaa ggaagcataa agataggcgg gatagcaata
     1201 agtgaatatt ctgacgaagc cttaattaaa gccatttcct ttgtttttca agattcaaaa
     1261 ttattcaaga agagcattta tgataatgta gctttagcta ataaagatgc gacgaaagat
     1321 gacgttatga gagccttaaa attagcagga tgcgatttaa tattagacaa attcccagaa
     1381 agagaaaata caatcatagg ctcaaaaggt gtttatttat ccggtggaga aaaacaaaga
     1441 attgcaattg ctagagcaat tttaaaggat tccaaaatta ttattatgga tgaagcatca
     1501 gcatctattg acccagataa cgagtttgaa ttgcaaaaag cttttaaaaa tcttatgaag
     1561 gataaaacag ttatcatgat tgcacacagg ctatctacaa ttaaagacct tgatgaaatt
     1621 attgtcatgg atagtggaaa aattatagaa agagggtctg acaaagaatt aatgtcaaaa
     1681 gatacaaggt ataagagcct gcaagagatg tttaacagtg cgaatgaatg gagggtttca
     1741 aatgaaagag ttttataaaa aaagatttgc tcttacagat ggaggagcaa gaaatttaag
     1801 taaagcaaca ctggcttcat ttttcgttta ttgtataaac atgcttcctg ccatattact
     1861 tatgattttt gctcaggaag ttttggaaaa tatgggcaaa agcaatggct tttatatagt
     1921 attctcagtt ttgactttga tagcaatgta tattttgctt tctatcgaat acgataaatt
     1981 atataacaca acctatcaag aaagtgcaga tttaagaata aggacagcgg agaatttatc
     2041 aaaattacct ctatcttact tttctaaaca tgacatttcc gacatttcac aaacaatcat
     2101 ggctgatatt gaaggcatag agcatgcaat gagccactca ataccaaagg tgggcggcat
     2161 ggtactgttt ttcccattaa tatctgtaat gatgctagcg ggcaatgtca agatgggttt
     2221 agctgtaatt attccatcta ttttaagctt tatatttata cctttatcta aaaaat
//
LOCUS       DAVLTG010000107         2188 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLTG010000107 DAVLTG010000000
VERSION     DAVLTG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.109"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            266..1669
                     /locus_tag="VYN12_002047"
     CDS             266..1669
                     /locus_tag="VYN12_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1416340.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1858..>2188
                     /locus_tag="VYN12_002048"
     CDS             1858..>2188
                     /locus_tag="VYN12_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416341.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEE"
BASE COUNT          792 a          278 c          427 g          691 t
ORIGIN      
        1 gattctctgg agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata
       61 tggggggaat ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat
      121 attaagtttg atagaatttc ttggagattt tgttatggat tataatttca atttggagca
      181 tcctttcttt ttcactaata atgattatag tacagatact agcataaagt actaagtaag
      241 tctgcctttt aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat
      301 tggaaaattt gttgaaagac aagggtggaa aatacacatt agttcagagt ataatagttc
      361 acacgaattg ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca
      421 tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc
      481 tggtaaattt attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt
      541 agaaagtgcc ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga
      601 agcaccaata tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt
      661 tgttattgat gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt
      721 taaaattcca aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga
      781 taaaaaacag ggagactttc cctttattat agataatgca attagatttt caaacagtgg
      841 tgggatatat aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag
      901 accgtataca ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg
      961 caaagcacta aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa
     1021 gatctgggag cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg
     1081 ggttaccaat aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag
     1141 agtttcaaag atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt
     1201 atatcatcaa gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat
     1261 aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc
     1321 ccctggtttt agagcatggc gagaaacact tcccagtgag atagattggt atggtattag
     1381 acaaatagct cattatttat acatgccact agtaactaca tcggatttga catacaacta
     1441 tgtaagtcaa accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga
     1501 acatatagat tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga
     1561 gaatatttcc aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga
     1621 gcaagatata caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc
     1681 ttagcaaacg ataaagtttt agggccgata caatcaattg cctattcatt aaataagata
     1741 aatacaacca aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt
     1801 gtagacgctg aacatgataa taacggactg tatacttcat caatagatga gatacacatg
     1861 aaagatgttg tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag
     1921 tcaccattta gggtattatt aacaggaact tctggcagtg ggaaaacaac gattttaaat
     1981 ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa
     2041 aagagttcag attcaatacc aacagttgat cagacaccat atatttttga cactactatt
     2101 cgtgagaacg taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg
     2161 ttaaaaaagg taaatctata tgaagaat
//
LOCUS       DAVLTG010000108         2188 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLTG010000108 DAVLTG010000000
VERSION     DAVLTG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.110"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            9..1292
                     /locus_tag="VYN12_002049"
     CDS             9..1292
                     /locus_tag="VYN12_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1416342.1"
                     /translation="MVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKE
                     KIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLF
                     YILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIIRAIESALEKVDE
                     YAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFE
                     EGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIP
                     IYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIY
                     HENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELL
                     TKTIKEYLIPLPPLPEQSRIVDKIEQFFAHINALI"
     gene            1349..2146
                     /gene="psrA"
                     /locus_tag="VYN12_002050"
     CDS             1349..2146
                     /gene="psrA"
                     /locus_tag="VYN12_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1416343.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          791 a          310 c          387 g          700 t
ORIGIN      
        1 tttctacatt ggttgaaatt gtcagaggtg gctctccacg accaatcaaa gattatctta
       61 cttctgaagt agatggaata aattggataa aaataggtga tactgaaaag ggtgaaaagt
      121 atataaataa tgttaaagaa aaaatcaaaa aatcagggct taacaaaact agatttgtaa
      181 aaaaaggtac atttttgtta actaattcta tgagttttgg tagaccttat attttgaatg
      241 ttgatggtgc aatacacgat ggatggttgg ctatttcgaa ctatgaaaac tcattaaata
      301 aagattacct attctatatt ctttcatcaa atgtagttta ttctcaattt ctatctctaa
      361 ttagtggagc tgttgtgaaa aacttgaata gtgataaagt tgcttctatt cttatccctc
      421 tccccccact atccgaacaa caacgcataa taagagcaat cgaatcagct ttagaaaaag
      481 tagatgaata tgctgaaagt tataatagac tagaacagct agataaagaa tttccagata
      541 aactaaaaaa atctattctt caatatgcta tgcaaggaaa attagttgaa caagacccaa
      601 atgatgaatc agtcgaagtt ttacttgaaa aaatacgagc agaaaaacaa aaactctttg
      661 aagaaggcaa gattaaaaag aaagatttgg acatttctat tgtttcccaa ggagatgata
      721 actcttatta tgaggaagta ccttgtgaaa taccagaaag ttgggaatgg gtgaggttaa
      781 acgatataac ctcctacatt caaagaggga agtctccaaa atattcaaat attcctatat
      841 accctgtgat tgctcagaaa tgtaatcaat ggtctggctt ttctattgac ttagcaagat
      901 ttattgatcc cgaaacagtt catagttacc agaaagaaag attactaaga gatggtgatt
      961 taatgtggaa ttcaacaggt ctaggtacgt taggacgatt agctatttac catgaaaata
     1021 aaaatcctta tggctgggct gttgcagata gccatgttac agttataaga gtcttatcgg
     1081 gggttattaa ttgccatttc atctataatt ttctttcctc tcctattgtt cagtcagtta
     1141 ttgaagaaaa agcgtcgggt agtacaaaac aaaaagaatt attaacgaaa actataaaag
     1201 aatatttaat ccccctccca ccccttcctg aacaatccag aatcgttgat aaaatcgaac
     1261 aatttttcgc ccatattaac gcactaattt agtataatag ttttacgtgc ggtggaattt
     1321 ctatcaaaca taagatagga gttttacgtt gaaagatttt gaattacatt tgaagaaagc
     1381 tggtttagct gaaaatactg tgcgttcgta cctttatggt gttcgatttt tcttggagaa
     1441 ttacgaactc aaaatggaag atttatttga atacaaagga tatttattag acaattttaa
     1501 acctaaaact gtcaatttgc gactacaagg agtaaataaa tatctggctt ttattggtca
     1561 tgatgatttg aaattaaaat ttgtcaaagt acagcaaaaa ccgtttttag aagatgtcat
     1621 tagccatgct gattaccttt ttcttaaacg tagtttgaaa aaagatggta ttttaaaatg
     1681 gcattttgtc gtttggtttt taggtgcaac tggggctcgt gtaagtgaac ttattaaact
     1741 aaaagtagag catgtagaaa tcggttattt tgacatttac tcaaaaggtg gtaaaattcg
     1801 tagactgtac attcctaaaa aattaagaaa tagttgtctt agttggttag aatcagaaaa
     1861 tcgccgaagt ggttatttat ttttgaataa atttaacgaa ccaattacag caagaggagt
     1921 tgctcaacag ttaaaaaatt atgctgataa atacaaaatg aatcctaaag taatttaccc
     1981 tcattctttt aggcatttat ttgctaagaa ttttttagcg aagtataatg atattgcctt
     2041 gcttgcagat ttgatgggac acgaaagtat agaaactact cgaatttatc taaggaaaac
     2101 agctactgaa caacaaaata ttgtagataa aattgttaat tggtaaaaaa taacaggtgg
     2161 tcaaactgac tacctgctat ttttgtga
//
LOCUS       DAVLTG010000109         2040 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLTG010000109 DAVLTG010000000
VERSION     DAVLTG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.111"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            33..1058
                     /locus_tag="VYN12_002051"
     CDS             33..1058
                     /locus_tag="VYN12_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1416344.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1048..>2040
                     /locus_tag="VYN12_002052"
     CDS             1048..>2040
                     /locus_tag="VYN12_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1416345.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNR"
BASE COUNT          716 a          291 c          364 g          669 t
ORIGIN      
        1 caatagactt gaaatatgtt taaggagttt ttatgaaaaa caaatttttt ctaatagcta
       61 ttttagctat gtgtatagtt tttagcgctt gttcttctaa ttctgttaaa aatgaagaaa
      121 atacttctaa agagcatgcg cctgataaaa tagttttaga tcatgctttc ggtcaaacta
      181 tattagataa aaaacctgaa agagttgcaa ctattgcttg gggaaatcat gatgtagcat
      241 tagctttagg aatagttcct gttggatttt caaaagcaaa ttacggtgta agtgctgata
      301 aaggagtttt accatggaca gaagaaaaaa tcaaagaact aaatggcaaa gctaacctat
      361 ttgacgattt ggatggactt aactttgaag caatatcaaa ttctaaacca gatgttatct
      421 tagcaggtta ttctggtata actaaagaag attatgacac tctatcaaaa attgctcctg
      481 tagcagcata caaatctaaa ccttggcaaa ctttatggag agatatgatt aaaattgatt
      541 caaaagcctt aggtatggaa aaagaaggtg atgagttaat caaaaatact gaagctcgta
      601 tatccaaaga attagaaaaa catccagaaa tcaaaggaaa aatcaaagga aaaaaagtat
      661 tatttactat gattaatgct gcagatacat caaaattctg gatttatact agcaaagatc
      721 caagagcaaa ttatttaaca gatttaggtc tagttttccc tgaatcatta aaagaatttg
      781 agagtgaaga tagttttgca aaggaaattt ctgcagaaga agcaaataag ataaatgatg
      841 ctgatgtaat cataacttat ggtgatgata aaactcttga agctttacaa aaagatcctc
      901 ttttaggtaa aataaatgca attaaaaatg gtgccgttgc tgtaattcca gataatacac
      961 cgttagcagc ctcatgcact ccaacaccac tttcaataaa ctatactatt gaagaatacc
     1021 taaatctttt aggaaatgca tgcaaaaatg cgaaataaaa aacaaataaa cctaggcata
     1081 atttttgtaa tctgcctagg tcttcttatt acaatatttt tgtcattaaa gcttggaaca
     1141 aaagaaatta atatcagaga ttttttagca gcttttggaa tgggtaatac aaatgatgat
     1201 tttattaaat caattatata taaaagaata cctagaacta tttttgcaat tttagcaggt
     1261 tctagtcttg ccataagcgg tgtattgatg caatcagtta ctagaaaccc aatagctgat
     1321 ccaggtatac tcggtataaa cacaggagca agtcttagtg tagtaattgg tctttctttt
     1381 ttaggaattt catcaagcat aagccatata agttttgcaa tcattggtgg cttagtaagt
     1441 gcaatttttg tatacgcgat tgctgtaagc ggaaaagcag gccttacccc tataaaactt
     1501 gccttatcag gaacttgtgt tagtatggct ttaagcagtt ttgtaagttt tttaatttta
     1561 ccgaataata acgtcttaga caaatttaga ttttggcaaa taggtagcct tggagcagct
     1621 acattatctt ctatatctac actactacct tttataattt taggtcactt gatagctata
     1681 tttatttcat cagatttaaa cgctttagct atgggtgatg aaatggctgt tggtcttgga
     1741 gttaatgtta ataggataag atcacttgca ataattgcaa gtgtgctttt atgttcaagt
     1801 attactgcaa ttggtggacc tattggcttc gtaggtctta tagttcctca cttttgtggc
     1861 ttatttataa gcaaagatat acgcacaatg accatttctt catcttttat aggtgcagag
     1921 ctcttgctta tatgtgatat aatcggccgt atgttaggta aaccaggtga aattgaagta
     1981 gggataatta ctgcaataat cgggggtcca gtacttattt atgtaactat gaaaaataga
//
LOCUS       DAVLTG010000110         2026 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLTG010000110 DAVLTG010000000
VERSION     DAVLTG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.112"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..1019
                     /locus_tag="VYN12_002053"
     CDS             <1..1019
                     /locus_tag="VYN12_002053"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1416346.1"
                     /translation="FGHSIYIYESETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPK
                     YYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNIL
                     GVAVAIWGGIYGSFFGYELPFHLISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVR
                     MKKYAEAYNSGFAWCVILLGLLFIAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQ
                     TKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLFPGILAKL
                     TIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKV
                     ITKN"
     gene            1035..1511
                     /locus_tag="VYN12_002054"
     CDS             1035..1511
                     /locus_tag="VYN12_002054"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV1416347.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1545..>2026
                     /locus_tag="VYN12_002055"
     CDS             1545..>2026
                     /locus_tag="VYN12_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416348.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     S"
BASE COUNT          643 a          276 c          400 g          707 t
ORIGIN      
        1 attttggaca ttctatttat atttatgaat cggaaacatt gacggataat caagatgaaa
       61 tacctatcaa attaacgaat cattctttaa ttgaaccatt tgaattattg acagaaatgt
      121 atgctctgcc caaatattat gagaaagatc ctacacctgt attagcacca ttttacttta
      181 cattttttgg aatgatggtt gctgatttag gctatggttt actattgttt ttaggaacaa
      241 tgttagcatt aaaaattttt catctacctt cagcaactaa gagattttta aaattcttta
      301 atatattagg ggtagccgtt gcaatttggg gtggaatcta tggctcattt tttggatatg
      361 agttgccatt tcatctgata tctacaacct ctgatgtcat gactatatta gtagtgtcag
      421 ttgtgtttgg gtttattaca gtatttgcag gtttgttagc ttcaggacta caaaaagtaa
      481 gaatgaagaa atatgcagaa gcatataatt caggatttgc gtggtgtgtt attctgcttg
      541 gcttgttatt tattgctgtt ggaatgttga tgcctgatat gagaccgtta tttgtattag
      601 ggaaatgggt atctattttt aatgctgtgg ggattttgat tgtttctatt attcaaacca
      661 aaagcttgtc aggtattgga gcaggattgt ttaatctata taacatttca tcttatatag
      721 gtgatttagt tagtttcact cgattgatgg cattaggatt atctggagca agtatagcat
      781 cagctttcaa tttaattgtt ggtttgtttc cgggaatatt ggctaaactg acaattggat
      841 tagtattatt cattctttta catgcgatca atatttttct atcgttacta tcaggatatg
      901 ttcatggagc acgtctgata tttgttgaat tttttggtaa gttttatgag ggtggaggaa
      961 aaccatttca acctttgaag gcttctgaga aatatattaa ggttattaca aagaattaat
     1021 ggaggatata tataatggaa catttagcaa cttatttttc aacctatgga ggagctttct
     1081 tcgctgcatt gggaattgta ttggcggttg gattaagcgg tatggggtct gcttatggag
     1141 ttggtaaggc tgggcaatct gccgcagctt tactgaaaga acagcctgaa aagtttgcct
     1201 cagctttgat attgcaatta ttgcccggaa cacaaggatt atatggtttt gttattggaa
     1261 ttttaatttg gttgcaatta actccagaac ttcctttaga aaaaggcgtt gcttatttct
     1321 ttgtagctct tccaattgct attgtaggat acttttcagc taagcatcaa ggaaatgtag
     1381 cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga attcatgaag ggagcaattt
     1441 tagctgccat ggtagaaacc tatgcaattc ttgcttttgt cgtatcattc attttgaccc
     1501 ttcgtgtata agaaataaat ttgcaattca aaggaggtgt ctaaatgagc aatttagaaa
     1561 acttacgaga gtctgttatt gaacaagctc atgaaaaagg gcgtatgaaa ttattggatt
     1621 ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc gctcattata aagaaaaaag
     1681 aagctgaaca tgaacgaaag ttaaaagaat tgcaacagaa atatcaaata atttttcaac
     1741 aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa acagaaaata ttaaaagaac
     1801 tttttcaatc tgctttacta gaaatggaat cttggagtgc agataaagaa atggagttca
     1861 tctatcgaat tctggaacga tattcacaac aagaggtcat agtaaccttt ggggaacgga
     1921 ctttagctaa attcaatttg gaacaattag agaaattgaa attctctttt ccaaattatt
     1981 tatttagtga acaacctatc tcaaatgaat caggcttact tatttc
//
LOCUS       DAVLTG010000111         2005 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLTG010000111 DAVLTG010000000
VERSION     DAVLTG010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.113"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            88..1262
                     /locus_tag="VYN12_002056"
                     /pseudo
     CDS             88..1262
                     /locus_tag="VYN12_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            1255..>2005
                     /locus_tag="VYN12_002057"
     CDS             1255..>2005
                     /locus_tag="VYN12_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1416349.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERI"
BASE COUNT          748 a          197 c          384 g          676 t
ORIGIN      
        1 aagcatgatt tactataaaa ttattgagtt attcataaaa atttctctat caaatatcat
       61 aatgcgtcgt ttaaggagat ggttacaatg caatatagtt gtggaaaaat aaatattaat
      121 atccctgatg gatatggaga cattaaggat atagtgtttt cggctcatat tatagttagg
      181 tataataatg gacattgtgg aggtatagat ccgcatataa ttggactttg taaaaagcag
      241 atcagaagga tgtctctata tcctattttg ataatcgtat ctagagattc aaaggttatt
      301 gatgattata aaaatttaga tattgcctat gttgattgta ctcaatgttc aaataatttt
      361 gaaactgcct tacacgttaa aaatatttta aaattattaa aaatccaact tatacactgt
      421 catggctact caactaatta ttttttatat atgttaaaaa aacttgacaa gaatggattt
      481 ggaaaggtta agacagtgat aacatgccat ggatgggttg aatataactt aaaaaagaaa
      541 ttcttgactt attttgattt ttggacatat tctatgggag atgcttttat ttgtgtatct
      601 gaaactatga aaaaaagatt ggagagtata ataaaaaaat aagaagatag ttgcaataaa
      661 taacggaatt aatgtatcaa atagcgattt agatgtagta ggtgttcaag actttaaaaa
      721 agaattttgt attccaaata acaaaaaaat catttgttat gttgaaaggt tggatccaga
      781 aaaaaggccg gatagattcc ttgaatttgc agaaaaatta tttttagtca gagaagatgt
      841 gatttttatt atggctggaa atggtagtat gtgggctgct ttgaaagaaa aaatttgcca
      901 tttgaaatgt agagataatt tcaggttact tggtgaaatc tatccagcta ctatagttta
      961 ccaaatatcg gatttattgt atattccttc tgatacagaa ggaataccta tgtgtgtttt
     1021 agagtcaatg tcacaaggaa ctccggtttt agctagtaat gttggcgggt taagtgaaat
     1081 tattgaacat agggttgatg gatttttatt tgagaaggaa gatgttgagg gagtgtgtgc
     1141 ttgtgctaat tttttactca atgattctga gtatttgaaa tatataggtg agaatagtaa
     1201 atcaaaaata agaaaacatg agagtatatg atgaattatt agagaagagt agtcatggat
     1261 aggaatatag atcaagaatt agtaagtatt ataataccaa cacataatag gtatgaatct
     1321 ctgattagag ctgtgaaaag ttgtttacat caaagttata aaaatatcga agttataatt
     1381 attgatgata attatagtaa tgtaaattta agaaataaaa ttatccatca atttggctat
     1441 accaatcata gaattaagtt aattttaagt aatgaagatt taggtgcaac taatgccaga
     1501 aacataggta tcaaaaattc tagaggtaag tatatatcat ttttagacga tgatgatgaa
     1561 tatatgccag atcgaatttt aaagttgatg gcttgtttta aaaagagtag aatgaagaat
     1621 ttagctttag tttatagtta tggaataata atttatccaa atggtacacg agaagaggag
     1681 aagaccgatt ttgttggaaa tcccttgttt gttcaaatgg ttcacaatat agcaggtacg
     1741 tcattttggt tgtgtaaaaa agaggtgcta gaattaatta atggttttga gaaaatagat
     1801 tcacatcagg acggtgttgt tttattaaaa ctacttgctc aaggatacca aattgatata
     1861 gtgcgagaat tcttggtgaa ttactacgct cacagtaaag aaaacggtat cactggagtg
     1921 acacaaaaaa caattaatgc agatgaagaa tattataatt actgtaggaa atattttaat
     1981 ttattgagtt tcaacgagag aatat
//
LOCUS       DAVLTG010000112         1928 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLTG010000112 DAVLTG010000000
VERSION     DAVLTG010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.114"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..975
                     /locus_tag="VYN12_002058"
     CDS             <1..975
                     /locus_tag="VYN12_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="HEV1416350.1"
                     /translation="RLINFGEEDKYYIKNNHDAIISPEIFTQAQEIRLRRSGNKKTIA
                     NTKGKRERYSRMYPFSSRLECGFCGTVLSRRSWHSSSEYKKIIWHCTTSIKKGKKHCI
                     HSKGIEEKAIENAFLQSYQQLFYENNNLTEDFLEIIKEELTDDTLKVELNKIVSKLNS
                     LYKKEEKLVSMNLDGKISDSVYEDKFNQIQIEKEKLLEEKVNLEVTLKSEVDIKSRLE
                     NFKEILTSQKTLTEFDKDIFDSIVEKIIVGGINSDGEIDPAMLTIIFKTGDSSTKDAK
                     SYKSKRKNAKIENDKLCFNTVTDDEKKCTNKENNARRDGSTFVQTRCR"
     gene            896..1243
                     /locus_tag="VYN12_002059"
     CDS             896..1243
                     /locus_tag="VYN12_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416351.1"
                     /translation="MTKKSVQIKKTTHVETVALLSKLDVDKHISVEIELDEMDLTSAE
                     SKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREHYNKSKKDKQIIPQCTPEKE
                     EAIMDALRHFKMI"
     gene            1457..1690
                     /locus_tag="VYN12_002060"
     CDS             1457..1690
                     /locus_tag="VYN12_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEV1416352.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
BASE COUNT          800 a          225 c          344 g          559 t
ORIGIN      
        1 cgtttaataa atttcggtga agaagataaa tactatatta aaaataatca tgatgcaata
       61 attagtccag aaatttttac acaggcgcaa gaaattcgat tacggagatc aggaaacaag
      121 aaaacaatag caaatacaaa aggaaaacga gaaagatatt caagaatgta tccttttagt
      181 agtagattgg aatgtggttt ttgtggtact gttctgtctc gaagaagttg gcactctagt
      241 tcagagtaca aaaagattat ctggcactgt acaacatcta taaagaaagg taaaaagcat
      301 tgcatccata gtaaaggaat agaggaaaaa gcaatagaaa atgctttttt acagagctac
      361 caacagttgt tttatgaaaa taataaccta actgaagact ttcttgaaat tataaaagaa
      421 gagcttactg atgatacctt aaaagtggag ttgaataaga tagttagtaa attaaattcg
      481 ttgtacaaaa aagaagaaaa attagtttca atgaatctag atggaaaaat aagtgattct
      541 gtatatgaag ataaattcaa tcaaatacaa attgagaaag aaaaactttt agaagaaaaa
      601 gtaaacttag aagtaacttt aaaatcagaa gttgatataa aaagtagatt agagaatttt
      661 aaagaaattt taacttcaca aaagactctg acggagtttg acaaggatat ttttgatagt
      721 atcgttgaaa aaatcatagt aggcggaata aattctgatg gagaaattga tccagcaatg
      781 ttgactataa tttttaaaac gggagattct tcgactaaag atgcaaaatc ttacaaatct
      841 aaaaggaaga atgctaaaat agaaaatgat aaattgtgtt ttaataccgt aaccgatgac
      901 gaaaaaaagt gtacaaataa agaaaacaac gcacgtcgag acggtagcac ttttgtccaa
      961 actcgatgtc gataagcaca taagtgttga aattgagctg gatgagatgg atttgacaag
     1021 tgcggagagc aaagcaacat atgctcaaat caaagaatat gtttggaata aatttgaatt
     1081 aaaagtttcg acattatata ttgcacagat aaaaaagaaa tgtggaatag aattacgaga
     1141 acattacaac aagtctaaaa aggataaaca aattattcca cagtgtacac ctgaaaaaga
     1201 agaagccatc atggatgctt tgagacactt caaaatgatt taatagaaaa gaatgacagt
     1261 atatgacttt ctgcatttat tacattccta cttggtatag gaacagctat tattcctttc
     1321 ttgcaaggta tcaattagaa aataggctca atataaagat tgataggatc atttttatat
     1381 ttaaaggagc gttgaaatga ttgataaagg caacaaaaaa ttttaggata aatttgctaa
     1441 gttgtatgcc ccttttatga aaaaagataa agaggtttat gataaagttt gtgaatatct
     1501 tagtcctcat ttgaataaag atatggaggt gcttgaactt gcttgttggt ttcgtgtcat
     1561 aacagttata gaggcaaata gttatgtaaa tataaggagt tcaagacttc taccaaagtt
     1621 taaaactcaa aaaataaata gttggtgtgc tgcttatagt atccatttta ataatggata
     1681 ttgtaattag cataccaatg aatttaaaga ttctttaaag agtcttattt tgtgatgaaa
     1741 atttaatatg taaatctcag acgatagaaa ttaaaaactc tatcgtcttt tttatactca
     1801 aaattaggag gtaaaaatgg taaggataag aggtcccact taaaacaatt tatggcaaaa
     1861 taaggacgga ataacacaac aaattctcta aaacaaatca ctaaatcaat gtaagattga
     1921 atgaaatc
//
LOCUS       DAVLTG010000113         1912 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLTG010000113 DAVLTG010000000
VERSION     DAVLTG010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.115"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            37..909
                     /locus_tag="VYN12_002061"
     CDS             37..909
                     /locus_tag="VYN12_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1416353.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            909..1703
                     /locus_tag="VYN12_002062"
     CDS             909..1703
                     /locus_tag="VYN12_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416354.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          661 a          298 c          325 g          628 t
ORIGIN      
        1 ttacttatcg gagatgaaag ttattctttt tcaactttga ttaaagtctt aaatagtgaa
       61 actgttcctg gagctagttt ttcgattatg gaaattagat taccaaaatt attagcagga
      121 attatagctg gctggtcttt tggattggca ggatttatct ttcaaactat gttaagaaat
      181 cctcttgcaa gtcctgatat aatcggtgtc acaagttctt catctattgc agcggtcttt
      241 tgcatattgg tattaaaaac aaatagttta actactggaa ttatttcaat aacttgtgga
      301 ctaacatcat ctttaatatt atttttacta gctaaaaaag atggtttttc agcagcaaga
      361 ctgataatat taggtattgg ttttcaagct gtcacaagag caggcacctc atttttattg
      421 ttgaaagtag caagatatga attacaagaa gttatgagat ggctcagtgg ctctttatct
      481 tttacaaagt tagatgacat acctcttgtt ctaatagtaa gtattattgc tactatatta
      541 gttttatttt ttaataaaag actagaaatt attgaacttg gtgaagaaat agcaatcgga
      601 cttggagcaa atcccgagct ttcaaggctt gttttaattt tttgcgctgt atctttaact
      661 gctttttcta cttcaattac aggaccaata gcttgtatat cttttttagc tggtcccata
      721 gccttaaata ttggcaagaa aagaagccca atattagctg gattggttgg aattttacta
      781 gttttgttat cagacatatt ctctcaaaat attttaccag ctagatatcc agtaggtgtt
      841 gtaactggct tgttaggttc accatactta atatacttac taataaaaat gaacaggagg
      901 aatatataat gaaaggtctg tggtcaaata atcttacctg cggttatgat gaaaaaataa
      961 tcttggaaaa tataaatata aaaatacctg aagaaaaaat atcagttatt attgggtcaa
     1021 atggttgtgg gaaatcaaca ctcattaaaa ccttgtctcg acttataaag ccattagagg
     1081 gagaagtatt gcttgataat aaatcaatta attcttataa agaaaaagat ttagcaaaac
     1141 acatagctat attacctcaa tctccaataa tccctgaatc aataacagta gctgatcttg
     1201 taagccgtgg tcgtttcccc tacagaaagc cttttaagag tcttggaaaa gatgaccttg
     1261 aaataataaa cagatcaatg gttaaggcca atgttgaaga tctagcaaat aacctagttg
     1321 aagaactttc tgggggtcaa aggcaaagag tatggatagc tctagcccta gcccaagata
     1381 caagtatcct acttttagat gagccaacta cttacttgga tatctcatat caaatagaac
     1441 tattagacct cttgactgat ctaaaccaaa aatataagac aaccatttgc atgattttgc
     1501 acgatataaa tctaacagca agatacgctg attacctatt tgcaattaaa gaaggtaaac
     1561 ttgttgcaga gggaaagcct gaagatatac taaatgataa actagttaaa gatatcttta
     1621 atcttgaagc aaaaattata cgtgacccta tttccaattc gcctctaatg attcctattg
     1681 gcaagcacca tgttaactct taataattga atattggaat tcatttaaaa gtcgcaaatt
     1741 ttgaactgac cctcaaaagt taggccaaaa aactaactaa aggaggtcag ttttttaatg
     1801 gcaaatacag cacagaattt aagataaaat gactctttgt caactgtagt gggttgaaaa
     1861 aaagctaagc tcgagaaagg acaaatttcg tcctttcttt tttgatattc ag
//
LOCUS       DAVLTG010000114         1862 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLTG010000114 DAVLTG010000000
VERSION     DAVLTG010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.116"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..263
                     /locus_tag="VYN12_002063"
     CDS             <1..263
                     /locus_tag="VYN12_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1416355.1"
                     /translation="SQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            358..787
                     /locus_tag="VYN12_002064"
                     /pseudo
     CDS             358..787
                     /locus_tag="VYN12_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            858..1016
                     /locus_tag="VYN12_002065"
     CDS             858..1016
                     /locus_tag="VYN12_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1416356.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            1109..>1862
                     /locus_tag="VYN12_002066"
     CDS             join(1109..1477,1479..>1862)
                     /locus_tag="VYN12_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1416357.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIRQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTIEDKVYNHA
                     LSKERSKVENIFAKVKTFKMISTTYRNHLNASD"
BASE COUNT          599 a          342 c          404 g          517 t
ORIGIN      
        1 cgagtcaata ctatttggag cccctttata acctcttgcg agagagacta ttgactcagc
       61 ccttacttca tgcggatgaa acttcttata gggtgctaga gagtgatagt cagctgactt
      121 actattggac ttttttgtca ggtaaagcag agaaacaagg gattacgctt taccaccatg
      181 atcagtgtcg aagtggttca gtagtacaag aattcctagg agattattct ggctatgtgc
      241 attgtgatat tttgcggcag taacttagga ctttagtcct ctagttctgc ctatgcgata
      301 gcagtccaag gtttaggagc aaggcgacgc taagcttggt aaacttcgaa ccgctcgtct
      361 gcttatcgtc aactggaaga agctgaactt gttggatgtt gggcgcatgt gagaaggaag
      421 ttttttgaag cgccccccca agcaagcgga taaatcatcc ttaggagcta aaggtttagc
      481 ttattgtgat cagttatttt ccttggaaag agactgggag gctttgccag ctgatgaacg
      541 actacagaaa cgtcaagaac atctccagcc cttaatggaa gacttctttg cttagtgccg
      601 gcgtcagtca gttttagcag gttcaaaact aggaagggca attgaataca gcctcaagta
      661 tgaagaaacc tttaagacca ttttgaaaga cggacatctg gtcctttcca ataatctagc
      721 tgaacgcgcc attaaatcat tggttatggg acggagtaaa agagtccagt ggactctttt
      781 agcctaagct cagtttaaaa aagcgagggt ggttattttc tcaaagtttt gaaggagcta
      841 aagcaagagc tattattatg agtttgttgg aaacagctaa acgtcatcaa ttaaatagcg
      901 agaaatatct atcctatctt ctagaatgtc ttccaaacga ggaaactctc gtaaacaaag
      961 aggttttaga ggcttattta ccatggacta aagttgtaca agaaaagtgc aaataagaaa
     1021 tctccagatt aggaactatc cgtgagttct ccagtctgga gatttttcaa tagacttcct
     1081 gcgaaacaaa atatggtata atagttctat gaatgatgaa gcaagtaaac aactaaccga
     1141 tgcacgattt aagcgtcttg ttggtgttca acgcacgact tttgaagaga tgttagctgt
     1201 attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagtct
     1261 agaagacctt cttatggcca ctcttcaata tgtgcgagaa tatcgaactt atgaacaaat
     1321 tgcggctgtt tttggtattc acgaaagcaa cttaatccgt cggagccaat gggttgaagt
     1381 aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagttctg aggacacggt
     1441 aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaagaatta gcgaattatt
     1501 ctggtaaaaa gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa
     1561 ttgtttcttt ggatatcact gtgaactatt gtcatgatat gaagttgttc aaaatgagtc
     1621 gcagaaatat cagacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga
     1681 agatatatcc tcaagcacaa acttcacgta aatccagcaa actcaaaccg ctaacaattg
     1741 aagataaagt ctataaccat gcgctatcta aggagagaag caaggttgag aacatctttg
     1801 ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg aaatcatcta aacgcttcgg
     1861 at
//
LOCUS       DAVLTG010000115         1862 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLTG010000115 DAVLTG010000000
VERSION     DAVLTG010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.117"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..224
                     /locus_tag="VYN12_002067"
     CDS             <1..224
                     /locus_tag="VYN12_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1416358.1"
                     /translation="FQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFG
                     FRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(298..1242)
                     /gene="manA"
                     /locus_tag="VYN12_002068"
     CDS             complement(298..1242)
                     /gene="manA"
                     /locus_tag="VYN12_002068"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1416359.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1374..1655)
                     /locus_tag="VYN12_002069"
     CDS             complement(1374..1655)
                     /locus_tag="VYN12_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1416360.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
BASE COUNT          566 a          425 c          327 g          544 t
ORIGIN      
        1 tttttcagac tgtctttaaa acctttctaa aggacaaaga gaaaatcgtc aacgcccttc
       61 aactacacta ttctaacgcc aaattggaag cgaccaataa tctcatcaaa cttatcaagc
      121 gcaatgcctt tggttttcgg aactttgaaa acttcaaaaa acggattttt atcgctctga
      181 atatcaaaaa agaaaggaca aaatttgtcc tttctcgagc ttagctgact tcaacccact
      241 acagttgaca aagagcctca aaaaggactt gagtaatgaa ctcaggccct ttctttttta
      301 tggatgacta acaattaatt ctaaatcttg cccttccaga gtccaagctt caacatcact
      361 tggtaggata aagtgtctcc ctttttggat tggatagttt ttcccgtcaa cagttagttg
      421 accttgacca gccaagacac tcaacaagct gtagtcagct gtcttttcaa agttaacttt
      481 tccagtaatt tcccatttgt aaactgcgaa gaaatcattg gatacaagga gagtggaacg
      541 tagatcatct gctttgattg tcactggacg gctatttgcg ggttcaccaa tgttcaagac
      601 atcgatagat ttttcaaggt gaagttcacg taaattgccc ttgtcatcct tacggtcaaa
      661 gtcatagaca cggtaagtgg tatcgctaga ctgctgggtt tcaagaatca agatacccgc
      721 cccgatagcg tgcatggtac cgcttggtac atagaagaaa tctcctgctt taactggcac
      781 ttttgtcaac agcgcatccc agttcttatc ctcgatttgc tggcggagtt cttcttttga
      841 cttggcattg tggccgtaga taatctctga accttcatcc gcagcgatga tgtaccagca
      901 ttctgttttt ccaagttcgc cttcatgctc tagtccataa gcatcgtctg ggtgaacttg
      961 aacgctgagc cagtcgttag catccaaaat cttagtcaaa agcggaaata caggctcagg
     1021 acgattgcca aataattcac ggtgttccgc atacaaagta gcaagatctg ttccctcgta
     1081 acgaccattg gcaactttag aaacaccatt tagatgagct gagatagccc agtactctcc
     1141 gactttttca cttgggatgt cgtagccaaa ctcatcacgt agcttggtac caccccagat
     1201 tttttcttgc ataactgatt gtaaaaataa tggttctgac atcttaatct cctgtctgat
     1261 ttttctcccc tcattatagc aaaaaaagag ttcgaattga actctttttt acatcttata
     1321 aagcagggag aagattttat aaaaatagta aacaaatgtg ctctactcga tgcttacacc
     1381 attgctataa atgacatgta ccaatagaag gacttcttct tgctacgttt gagagtccca
     1441 tttcctacat tatctcgatc tacatagata aagccatagc gcttattcat ttcccctgtg
     1501 ccagctgaaa ccgaatcgat acagccccat gtcgtataac caagcaagtc aaccccgtct
     1561 ttgtaaatgg catctcgcat ggccttgatg tgggcctcta agtaagtaat ccgatagtca
     1621 tctgctacat aaccattctc atccggtgta tccatagcac cgagtccatt ttctacgata
     1681 atactatact aaaatcaaaa agcattatat aatagtgata tgaaatcaac taaagaagaa
     1741 atccaaacca tcaaaacact ttttaaagac tctcgtacag ctaaatatca taaacgcctt
     1801 caaatcgttc tatagtaaaa cgaaacaaga acagggcaaa tcgatcagga cagtcaaatc
     1861 ga
//
LOCUS       DAVLTG010000116         1818 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLTG010000116 DAVLTG010000000
VERSION     DAVLTG010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.118"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            633..854
                     /locus_tag="VYN12_002070"
     CDS             633..854
                     /locus_tag="VYN12_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416361.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            938..1741
                     /locus_tag="VYN12_002071"
     CDS             938..1741
                     /locus_tag="VYN12_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1416362.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
BASE COUNT          582 a          373 c          330 g          533 t
ORIGIN      
        1 cttcatatcg cctgaacgag agttggatac ttggcttcta agtcccaagc ccgttcccaa
       61 gcgaaatatg gacttattag tagatgattc actagcagga gatatcattt tactatggag
      121 aatccagttt ggtactttta ccactgaaac atgattttaa aaactcccat tcgaatatga
      181 ttcaaaattc gcttagaatc aatgttttcc cactttttca aaaaataaat tttcatctaa
      241 tttaaataac tttcaattaa gtgtgaattt tgcttaaaat cattaaaaaa caccccatgg
      301 tgtgaaccat gaagtgttgt aaatgctgtg ttgtagctag ttcttagcgt ttagagaact
      361 ggctagcttt acgagctttc ttaagatctg gtttccaaaa tactttgagt acacttatgg
      421 tattgatgcc cctaaacatc taaaaactct ggtagaaaaa gggtatgctc ttgtcgaaac
      481 ttcttttgac tcacttgacc atctaaatac taccatgaaa aagaatatcc tgaagaagaa
      541 gggagttact ggactttcta aaatgaaatc ttgcgacctg gatcaagccc ttcatgagca
      601 tttttcagaa gaagaattag ctggtcactt tcatgtcctt ctatggactt ttttacaatg
      661 gcattgctat cacacccaat acctatctaa gcgcctggtt cgtaaacttt attgcagctc
      721 ttcctctaaa tttcctaatt gttgaaccaa ttgcccgttt tatactaagt tcttttcaga
      781 aaccatttac tggggaagaa gttgaagaag ttgaagattt tcaagatgat gatgaaatcc
      841 caactattat ctaagccagt tctgtaaact actaatattt gaaatccact tccttttagg
      901 gtacaatggt tataaatgaa tttttgagag gatcagaatg aaaaaactag caacccttct
      961 tttactgtct actgtagccc tagctgggtg tagcagcgtc caacgcagtc tgcgtggtga
     1021 tgattatgtt gattccagtc ttgctgctga agaaagttcc aaagtagctg cccaatctgc
     1081 caaggagtta aacgatgctt taacaaacga aaacgccaat ttcccacaac tatctaagga
     1141 agttgctgaa gatgaagccg aagtgattct ccacacaagc caaggtgata ttcgcattaa
     1201 actcttccct aaactcgctc ctctagcggt tgaaaatttc ctcactcacg ccaaagaagg
     1261 ctactataac ggtattacct tccaccgtgt catcgatggc tttatggtcc aaactggaga
     1321 tccaaaaggg gacggtacag gtggtcagtc catatggcat gacaaggata agactaaaga
     1381 caaaggaact ggtttcaaga acgagattac tccttatttg tataacatcc gtggtgctct
     1441 tgctatggct aatactggtc aaccaaacac caatggcagc cagttcttca tcaaccaaaa
     1501 ctctacagat acctcttcta aactccctac aagcaagtat ccacagaaaa ttatcgaagc
     1561 ctacaaagaa ggtggaaacc ctagtctaga tggcaaacac ccagtctttg gtcaagtgat
     1621 tgacggtatg gatgttgtgg ataagattgc taaagccgaa aaagatgaaa aagacaagcc
     1681 aactactgct atcacaatcg acagcatcga agtggtgaaa gactacgatt ttaaatctta
     1741 aaaaccaaaa aaatacagta tccacattcg gtactgtatt tctggctcta taatatctat
     1801 agtgggtaaa tccactat
//
LOCUS       DAVLTG010000117         1760 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLTG010000117 DAVLTG010000000
VERSION     DAVLTG010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.119"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..235
                     /locus_tag="VYN12_002072"
     CDS             <1..235
                     /locus_tag="VYN12_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416363.1"
                     /translation="GGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNL
                     GISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            250..990
                     /locus_tag="VYN12_002073"
     CDS             250..990
                     /locus_tag="VYN12_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416364.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            993..>1760
                     /locus_tag="VYN12_002074"
     CDS             993..>1760
                     /locus_tag="VYN12_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1416365.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIII"
BASE COUNT          588 a          227 c          328 g          617 t
ORIGIN      
        1 tggaggtcaa aaacaaaaaa tagctttagc tagagctctg attagaaata ataaagtgta
       61 cttatttgac gaaatatcag ctaatttaga taatgataat tcaaattcca tacatgatat
      121 tctgttcaat ttaggtattt catttattga agtttcacat cattatgact taaatgacaa
      181 gagatacact gatatatata aattggaaaa tggaacactt ttcaaaatta agtgattgga
      241 ggcaagaata tggataaaga ttatatatta aaagtgaaag ggctgtatca tcaattttta
      301 ctaggaaata ataaaacgtt gcaagtgctg aaaaatgttt ctctttctgc ttcgagagga
      361 gaatttataa gtattctagg aattagtggt tctggaaagt caactttatt aaaatgtatt
      421 tctagtttgc ttgaaccaac aagtggggaa gtaattttaa atggaatcaa cccctataaa
      481 atcagaaatg caaaattgtc aagtataaga cgtaacgaag tatcttttat atttcaagca
      541 tacaatttaa taccttccct gccggtaata gaaaatatag cacttccttt gcgattatca
      601 caaaaaaaat taactattaa aaatgtagaa aacttactca aaagaatgaa gtttaatgct
      661 ggcttaaacg attttgttgg aactctgtct ggtggagaac aacagaaggt tgctatagct
      721 agagcggtta ttgctgatag tgatataata tttgctgatg agccaactgg ggctttagac
      781 agcgtttctc gtgaagtaat ttttgaatta ttgagagagt tagtaggggc gggtaagtgt
      841 gtaattatgg taacgcacga tatagaattg gcctcgaaaa ctgatcgtgc attaatattg
      901 aaagatggaa aaattttcaa agaacttcat agacctagcg gggaagagtt gtataaaatc
      961 ttagaggtac aatcaactac ggaggaatag agatgctcag attagtttac tatcaatttt
     1021 tacataataa gaaacaatgg ttaggcgttt caccagtaat ttttgtttcg agtttagtta
     1081 tgggattggc tgttaatggg gtaattaatg ttgagaataa ttcgcaagta tttgtcggac
     1141 ttccagatcc taaaccaatt tttatgtttc cgatagtatt cggaggagta acattattct
     1201 ttgtgctctc taacataata aatatgttgg ttgaaatttt tagagatgat tacgaacttc
     1261 tggaggtgtt gggagcaagt cgccttcaac tatcatttct tgtgggggga cagattttta
     1321 tcatttcctc gattattagt tttattgcat atctatgctc tatatttgtt acgtcaaatt
     1381 attattattt tttacaatac tttttcgggg aaaatatatt acctgatatc caatttcaaa
     1441 cgagtgctgt tggatgtatc attacagtag tgttgatttc atttttagcc tttctaagtg
     1501 gttgctttta tacgttcaag aagattagaa ataggaagag ttctaaaata aggcatgttc
     1561 tttcaatagt aaaaagaata ctgctattgg ctggttttag tgttatctgg ttgctttctt
     1621 tgcaacaaat tttccaagat agcacaattt tagcgaaggc ccagataata ttcaatattg
     1681 taatcttaga tattgtgatt atttatcaat tatctccttt tatacagtca tgttttatca
     1741 aactactttc tataattata
//
LOCUS       DAVLTG010000118         1674 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLTG010000118 DAVLTG010000000
VERSION     DAVLTG010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.120"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            84..491
                     /locus_tag="VYN12_002075"
     CDS             84..491
                     /locus_tag="VYN12_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1416366.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VYN12_002076"
     CDS             656..955
                     /locus_tag="VYN12_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1416367.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VYN12_002077"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VYN12_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1416368.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          567 a          329 c          294 g          484 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctg
//
LOCUS       DAVLTG010000119         1619 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLTG010000119 DAVLTG010000000
VERSION     DAVLTG010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.121"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..742)
                     /locus_tag="VYN12_002078"
     CDS             complement(<1..742)
                     /locus_tag="VYN12_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416369.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLY"
     gene            complement(899..1144)
                     /locus_tag="VYN12_002079"
     CDS             complement(899..1144)
                     /locus_tag="VYN12_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416370.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
BASE COUNT          617 a          283 c          202 g          517 t
ORIGIN      
        1 tataaagcaa aggtaaaact ttataaaaaa tatctaagtc aacctcactc tgattctgaa
       61 gcaagtagga gtcaagcaaa ttttcaaaaa tagctatcaa tatgattggt gtaaggtttt
      121 tgtattcaca tgtcaagtat tctgagtatc gtgcagatga tatttctttt acataacttt
      181 ttgaaagcaa gattttttca aattcatcat ctattattaa tcttctattt ccaatccaag
      241 cggtattacc acccaaataa gattgtacaa atagcaatat gtaagaaaat atgaacgtaa
      301 atactgaaag aggtagaatt ctatgcgtaa aaaaatagac gataatggta gccaggagta
      361 aagatatctc tcgtgacaat cgaattcttt tcagcatctt ttttaacagt ccgtaaggtt
      421 gtccttggca atattcttga actaaattaa tcggaatgac atctctcacc atttctggaa
      481 agtagagtaa gtttataggt tgaaatctcc aactcccatc ataagtaaat ggatatagaa
      541 ccaaatactt aaaagatttt tttcttataa acttaattat cacaatatga atgactgttg
      601 caatgaagta tattaaatat aaaagtaaaa ccgccatcaa tatacttaca aaaatcccct
      661 tggactcaat caatggaaaa taaaatattg caactagaag cgaataaagt cccgctaata
      721 aatatttctg atcatctttc attcaaaaca ccatattatt tactaagaat acatcaatac
      781 aatagagcaa ctctgtaagt caatatttga taaagcaaag ctttaacccc ttccccagac
      841 gttagctttt cttcaaccca ctacagttga caaggagccc aaattattga taaaaacttt
      901 agtcatcatc gtctctataa aaatattttc tatacactct tgataatacc aaaattaatg
      961 ccaatatcat accaagagct ataataatag aatttattag atttatttta gtatatccaa
     1021 tcactagtcc aataattgga ctagcagaca tgcttagata taataaaaat aacaaaaaat
     1081 gaatttcacc aattcctgca aaaaaatgtt tcatagctat agttttacgc ccataaatac
     1141 ccatcaaatt taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaag
     1201 acttcagcaa cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca
     1261 ccaatatatc ttgttatagc acttagttac ctagataaga tatcctttag cttgcttcca
     1321 aaatttaagt ctacacctat aatatgagtt catattagta ctgctaaatc ctatctatag
     1381 taatgtcaaa cacctaaata aagtcatctc tccaattcat tcaagaaatg aagaaaggca
     1441 aaaaatcttt aaaataagaa aagtgcatat tatcaggtgt tcaaaaatat tgatgatata
     1501 cgttatatag atagaaagat ttactcaatc tcactttcaa attgagtttt ttcccaacct
     1561 cgtttttaat ttatatcttc aataaaatct aatgacctag ttgatatgtc atatggaat
//
LOCUS       DAVLTG010000120         1498 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLTG010000120 DAVLTG010000000
VERSION     DAVLTG010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.122"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            29..1375
                     /gene="gdhA"
                     /locus_tag="VYN12_002080"
     CDS             29..1375
                     /gene="gdhA"
                     /locus_tag="VYN12_002080"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1416371.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          460 a          294 c          321 g          423 t
ORIGIN      
        1 taaaatatga caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt
       61 gtttgaaact gtgaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga
      121 atttttcaac actttagaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat
      181 cttggcacgt attactgagc ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg
      241 tgatggaaaa gttcaagtaa accgcggtta ccgtgttcaa ttcaactcag ctgttggacc
      301 atacaaaggc ggacttcgtt tccacccaac tgtaaaccaa gggatcttga aattcctcgg
      361 atttgaacaa atctttaaaa atgtcttgac tggacttcct atcggtggag gtaaaggtgg
      421 atcagacttc gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt
      481 catgactgaa ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg
      541 tgttggtgga cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga
      601 tgctggtgtc ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc
      661 aactggttac ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt
      721 tgctggtaag aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa
      781 agcaactgaa ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga
      841 tgaaaatggt atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt
      901 gactgagtat gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta
      961 cgctggaaac tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc
     1021 agctaaacgt ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccaag
     1081 cgaccttgat gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgcaaaagc
     1141 tgccaacgct ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct
     1201 ctcatggact cgtgaagaag ttgatggccg tctcaaagac atcatgacaa acatcttcaa
     1261 cacagctaaa acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa
     1321 cattgctgcc tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt
     1381 atttactcaa tcctcaatca ctacgattgg ggatttttag cttgaattaa aaaattggaa
     1441 aatctaatta aataaaatga aatgcaataa aaactgaaca aattgattgc ggaattca
//
LOCUS       DAVLTG010000121         1497 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLTG010000121 DAVLTG010000000
VERSION     DAVLTG010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.123"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            49..273
                     /locus_tag="VYN12_002081"
     CDS             49..273
                     /locus_tag="VYN12_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1416372.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSAYSKMEAGNRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            409..549
                     /locus_tag="VYN12_002082"
     CDS             409..549
                     /locus_tag="VYN12_002082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416373.1"
                     /translation="MRQMIYNDTSDRSGCHRKRAASEILMMTSSVMPWRRLIKDKKEV
                     IF"
     gene            731..>1497
                     /locus_tag="VYN12_002083"
     CDS             731..>1497
                     /locus_tag="VYN12_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1416374.1"
                     /translation="MSNNVEIIKANPLVTRRNDNSGSSSRRVAAYCRVSSDSDDQKNS
                     YDSQVRHYREYISQHQDWNLVDIYADEGISGTQVGKRQDFQRLISDCLDGKIDYIITK
                     AIARFARNTLDTLKYVRLLKDKQIGVFFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMQRGELIGFQGCLGYDYNQDTKSISINEKEAKIVRYIFERYIDGIGG
                     KAIARELDELGYKTPRGLDHWQDTTVLGIIKNEKYKG"
BASE COUNT          571 a          186 c          296 g          444 t
ORIGIN      
        1 ttaaaaataa gaaaataact atattatact tgttttagga gacaacagat gttgaaaagg
       61 attagagatt tacgtgaaga tgatgatttg acacaagaat atattgcgaa aatcgttttg
      121 aattgtacaa gatcagctta ttctaaaatg gaagctggta acaggttaat ctctataaat
      181 gaccttatca aacttgcaga tttttataag gtgagtctag actaccttgt aggtcgagtg
      241 gataataaag aagaccatta ctccaaaaag tagttggtta agaaagcaca ttgacaattg
      301 aataatccaa aatggtactt tcctcatttg tggagcagat ttgaatggct cgccatgata
      361 agagcgattt taaaaccatc aataaaatag agcgatactt tatatgccat gagacaaatg
      421 atatacaatg atacttctga ccgttcaggc tgccaccgta aaagagcagc aagtgaaatt
      481 cttatgatga cttcatcagt catgccatgg aggagattaa taaaagataa aaaggaagtg
      541 attttttgaa atcaaattta gaaaattata tagttgagct agagatgcta aatctattat
      601 tcctacaaaa acttattagc gaaaaagaat atgaaaaaat aaagctgaaa ctgcgtaaaa
      661 tatacacaaa ttagctgacc ttttttattg gttgcggtaa aataaatgca gagaaatagg
      721 aggttaagcc atgtcaaata atgttgaaat tataaaagca aatcctttag taactagaag
      781 aaatgataat agtggttctt catcgaggag agtagcagca tattgtcgtg ttagttccga
      841 tagtgatgat caaaaaaata gctatgattc tcaagttcgt cattatagag agtatatatc
      901 acagcaccaa gattggaatt tggttgacat ttatgctgat gaagggattt caggaactca
      961 agttggaaaa agacaagatt ttcaaagatt gatttcagat tgccttgatg gaaaaataga
     1021 ctatatcatt actaaagcta ttgctcgatt tgctagaaat acattagata ctctcaaata
     1081 tgttcgtttg cttaaagata aacaaattgg agtatttttt gaagaagaaa acattgatac
     1141 tttaactatg gatggtgagt tgctattaac gatattgagt tcggtggctc aacaggaagt
     1201 tgaaaataca tctgcccatg ttaaaaaagg tttaaaaatg aagatgcaac gtggagaact
     1261 tattggtttt caaggttgtc ttggttatga ctataatcaa gatacaaagt caatatcaat
     1321 aaatgaaaaa gaagccaaga tagtacgtta tatttttgaa cgatacattg atggtattgg
     1381 gggtaaggca atagctagag aactagatga actaggttat aaaactccga gaggtcttga
     1441 tcactggcaa gatacaacag ttttaggaat tattaaaaat gagaagtata aaggtga
//
LOCUS       DAVLTG010000122         1489 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLTG010000122 DAVLTG010000000
VERSION     DAVLTG010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.124"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..>1489
                     /gene="pcpA"
                     /locus_tag="VYN12_002084"
     CDS             <1..>1489
                     /gene="pcpA"
                     /locus_tag="VYN12_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1416375.1"
                     /translation="KTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQ
                     NNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQ
                     AFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFD
                     FSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLP
                     KSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKT
                     PKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAF
                     YGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHI
                     KNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVA
                     KPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNES"
BASE COUNT          573 a          205 c          249 g          462 t
ORIGIN      
        1 aaaaaactac aatattatca ttaactacag ctgcggttat tttagcagca tatgtcccta
       61 atgaaccaat cctagcggat actcctagtt cggaagtaat caaagagact aaagttggaa
      121 gtattattca acaaaataat atcaaatata aggttctaac tgtagaaggt aacataggaa
      181 ctgttcaagt gggtaatgga gttactcctg tagagtttga agctggtcaa gatggaaaac
      241 cattcacgat tcctacaaaa atcacagtag gtgataaagt atttaccgtt actgaagtag
      301 ctagtcaagc ttttagttat tatccagatg aaacaggtag aattgtctac tatcctagct
      361 ctattactat cccatcaagc ataaaaaaaa tacaaaaaaa aggcttccat ggaagtaaag
      421 ctaaaactat tatttttgac aaaggcagtc agctggagaa aattgaagat agagcttttg
      481 atttttctga attagaagag attgaattgc ctgcatctct agaatatatt ggaacaagtg
      541 cattttcttt tagtcaaaaa ttgaaaaagc taaccttttc ctcaagttca aaattagaat
      601 taatatcaca tgaggctttt gctaatttat caaatttaga gaaactaaca ttaccaaaat
      661 cggttaaaac attaggaagt aatctattta gactcactac tagcttaaaa catgttgatg
      721 ttgaagaagg aaatgaatcg tttgcctcag ttgatggtgt tttgttttca aaagataaaa
      781 ctcaattaat ttattatcca agtcaaaaaa atgacgaaag ttataaaacg cctaaggaga
      841 caaaagaact tgcatcatat tcgtttaata aaaattctta cttgaaaaaa ctcgaattga
      901 atgaaggttt agaaaaaatc ggtacttttg catttgcgga tgcgattaaa cttgaagaaa
      961 ttagcttacc aaatagttta gaaactattg aacgtttagc cttttacggt aatttagaat
     1021 taaaagaact tatattacca gataatgtta aaaattttgg taaacacgtt atgaacggtt
     1081 taccaaaatt aaaaagttta acaattggta ataatatcaa ctcattgccg tccttcttcc
     1141 taagtggcgt cttagattca ttaaaggaaa ttcatattaa gaataaaagt acagagtttt
     1201 ctgtgaaaaa agatacattt gcaattcctg aaactgttaa gttctatgta acatcagaac
     1261 atataaaaga tgttcttaaa tcaaatttat ctactagtaa tgatatcatt gttgaaaaag
     1321 tagataatat aaaacaagaa actgatgtag ctaaacctaa aaagaattct aatcagggag
     1381 tagttggttg ggttaaagac aaaggtttat ggtattactt aaacgaatca ggttcaatgg
     1441 ctactggttg ggttaaagac aaaggtttat ggtattactt aaatgaatc
//
LOCUS       DAVLTG010000123         1445 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLTG010000123 DAVLTG010000000
VERSION     DAVLTG010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.125"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            19..495
                     /locus_tag="VYN12_002085"
     CDS             19..495
                     /locus_tag="VYN12_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1416376.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFSRIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            495..1256
                     /locus_tag="VYN12_002086"
     CDS             495..1256
                     /locus_tag="VYN12_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1416377.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          530 a          202 c          289 g          424 t
ORIGIN      
        1 aaaataaagg agtttgctat gattggaaag aacataaaat ccttacgtaa aacacatgac
       61 ttaacacaag acgacttttc ccgaattgta ggaatttctc gaaatagctt gagccggtat
      121 gaaaatggaa ctagttcagt ctctacggaa ctaatagaca tcatttgtca gaagtttaat
      181 gtatcttatg tcgatattgt aggagaagat aaaatgctca atcctgttga agattatgaa
      241 ttgactttga aaattgaaat tgtgaaagaa agaggtgcta atctattatc tcgactctat
      301 cgttatcaag atagtcaggg aattagcatt gatgatgaat ctaatccttg gattttaatg
      361 agtgatgatc tatctgactt gattcatacg aatatctatt tagtagaaac ttttgatgaa
      421 atagagagat atagtggcta tttggatgga attgaacgta tgttagagat atctgaaaag
      481 cggatggtag cttaatggaa atccaagatt atactgatag tgaattcaaa catgctttag
      541 caaggaatct tcgttcactg acaagaggaa aaaagtccag taagcaacct atagcgattt
      601 tgcttggagg gcaaagtggt gccggtaaga ctacaattca tcgtattaaa cagaaagaat
      661 ttcaaggaaa tattgttatc atagatggtg atagttttcg ttctcagcat ccacactatt
      721 tagaactgca gcaagaatat ggcaaagaca gtgtagaata taccaaagat tttgcaggaa
      781 aaatggtaga gtctttagta acaaaattga gtagtttgag atacaatctt ttgatcgagg
      841 gaactttacg aacagttgat gttccaaaga aaacagcaca actcttgaaa aataagggat
      901 atgaagtaca attggcctta attgcgacaa agcctgaatt gtcgtatcta agtactctta
      961 tccgttatga agaactgtac attatcaatc caaatcaagc acgcgcaact ccaaaagaac
     1021 atcatgattt cattgtaaat catctagttg ataatacacg acaattggaa gaactggcta
     1081 tctttgaaag cattcaaatt taccaacgag atagaagttg tgtatatgat tcaaaagaaa
     1141 atacaacttc agcagcagat gttcttcaag agttactctt tggggagtgg agtcaggtag
     1201 agaaggagat gttgcaggtg ggggaaaaga gacttaatga attacttgaa aaataaacaa
     1261 ttgatatttt taggagaata gaaatgagag ggtttaataa caagataaag tctgtttatc
     1321 aagaactaac aaattccaaa gagaaattcg gtagctttca caagacttta attcatttgc
     1381 atacacctgt ttcttatgat tacaagctat tttctaattg gactgcaacg aaatatagaa
     1441 aaatt
//
LOCUS       DAVLTG010000124         1368 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLTG010000124 DAVLTG010000000
VERSION     DAVLTG010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.126"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..684)
                     /locus_tag="VYN12_002087"
     CDS             complement(<1..684)
                     /locus_tag="VYN12_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416378.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKR"
     gene            complement(694..1224)
                     /locus_tag="VYN12_002088"
     CDS             complement(694..1224)
                     /locus_tag="VYN12_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416379.1"
                     /translation="MNNYFNRLECRIRLKSIKHFTSFSFKLAALSTGIWTATLFLLIF
                     LIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSYIAYYFFLSLLTISSFS
                     WFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMVNSNPYALIYWLTLLSI
                     IIPLTVFSVHRNWRRV"
BASE COUNT          584 a          252 c          167 g          365 t
ORIGIN      
        1 cctcttttga cgagtgaaat agaaaatact tttaaaaaga aagactaaaa atagcaactg
       61 aagaaataaa tctcgtccta tatctccatt ccctcgattc aaaatataaa atagataatt
      121 agttcgattt cctacaaata gaccaccaaa cacaatcatg agtaaaaaga aactaacgca
      181 agcaaagttc atttgtacat tcgctcctag tgcgtataac ataaagcaaa acaagactaa
      241 cacacaagca ttcaaagaat caactataaa caaaactcct atatcccagt ttggtaactg
      301 taacataaat tgaatcacta gaacttttac catgattaaa atgagtccat aaagaaaaca
      361 ggtccaaatc tgatacctaa tccagagctt aatagaagaa aatcgaatca cttccataaa
      421 gaaatcggat gctcttctac gatatacaac tgctagaaaa aatgtatgaa taataaacca
      481 atgaagcaac catatagata agactaaaaa agagttttga ctcagattag gcccttttaa
      541 aatttctata acaagtctat catttccttc taaccaatac cataatccta aacaaatcaa
      601 tatccaaaaa agaacataac cccaaaagta cttggtatag attatctgat tcaacctcca
      661 catgtgacta cttaactttc ccatttccaa cttttacact ctcctccagt ttctatgaac
      721 agaaaataca gtcaatggaa ttatgataga tagtaatgta agccaataaa tcaatgcata
      781 cggattggaa tttaccatat actgaaaaat tggcaataat ccaattatcc cattgtccaa
      841 ctgataaatc cagaataagg attctacaaa taaaaaagta aacagaaata ctaagctcat
      901 gtttgatttt ttaaaccaag aaaaactgct aatagtaagt aaggataaaa agaaatagta
      961 tgctatataa gagaaaaaaa atcctataaa gaaactagca ttgtttgcaa tacttatacc
     1021 ataaaattct cttaaaaaat caacctcctt tatctccaaa gagaagctaa aaccattact
     1081 aaatgcaatt agaaaaatca ataaaaataa agtcgccgtc caaatccccg tactaagagc
     1141 tgctaatttg aaactaaaac tggtaaagtg cttaattgat ttcagacgaa tgcgacactc
     1201 caacctatta aaatagttat tcatcaaata aaaaaagaac aatatatatg tgaacggaaa
     1261 gcaatatact ccagtcgtca tatcttgaag taaaactaag atccattcta atacatttgg
     1321 atggattgaa tattggcgac agcgcaataa atatactgta ctagataa
//
LOCUS       DAVLTG010000125         1362 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLTG010000125 DAVLTG010000000
VERSION     DAVLTG010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.127"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            26..865
                     /locus_tag="VYN12_002089"
     CDS             26..865
                     /locus_tag="VYN12_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1416380.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            972..1247
                     /locus_tag="VYN12_002090"
     CDS             972..1247
                     /locus_tag="VYN12_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1416381.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT          452 a          210 c          291 g          409 t
ORIGIN      
        1 atcctaaaat agaaagattg atactatgac aaaaattaag attgtaaccg attcatctgt
       61 tactattgaa cctgaactag taaagcaatt agatattaca attgttccat tatctgtaat
      121 gattgataat gttgtttatt ctgatgcgga tttgaaagaa gaaggtaaat ttcttcagtt
      181 gatgcaagaa agtaagaatc ttccgaaaac aagtcagcca cctgtaggtg tctttgctga
      241 gatttttgaa gacctatgca aagatggtgg ccagattctt gctattcata tgtcccatgc
      301 tctttcgggt acggtagaag cagcacgcca aggtgctagc ctatctactg cagatgtgac
      361 tgttgttgat agttccttca ctgaccaagc cctgaaattc caagttgttg aggctgcgaa
      421 gttagctcaa gaaggtaaag atatggaggc aattttatct catgtagaag aggttaaaaa
      481 ccatacagag ctttatattg gtgtttcaac tttggaaaat cttgtcaaag gtggacgaat
      541 tagccgtgta actggcttgt tgagctctct tctcaatatc cgtgttgtca tgcaaatgaa
      601 agaccatgaa ttgcagccaa tggttaaagg tcgtggaact aaaacattta aaaaatggtt
      661 agatgagttg ataacatcgc tttctgaacg tgctgtagca gagattggaa tttcatattc
      721 tggtagtgat gattgggcaa aagagatgaa agaaagctta caagcttatg ttgaaaagcc
      781 aatttctgtt ttggaaacgg gttccattat tcaaactcac acgggtgaga acgcttgggc
      841 tattttgata cgttaccact cctaaaaaaa taaataaaat gggaagaaat agcgttttta
      901 acttgaccta aaagggattt taggatatga ttatatttgt taattagaaa ttatttggag
      961 gaatcattaa catggcaaac aaacaagatt tgatcgctaa agtagcagaa gctacagaat
     1021 tgactaagaa agactcagca gcagcagttg aagctgtatt tgcagcagta gctgactatc
     1081 ttgcagctgg tgaaaaagtt cagttgatcg gttttggtaa ctttgaagtt cgtgagcgcg
     1141 cagaacgtaa aggtcgcaac ccacaaactg gtaaagaaat gacaattgca gcttctaaag
     1201 taccagcatt caaagctggt aaagctctta aagacgctgt taaataatca gtctttaaaa
     1261 agcctattgt atcaagcttt ctagcttggt cagtaggctt tttaattatg aaatctagta
     1321 ataaatagag ttaaaaagtt gaatgttccg aaaatattgt at
//
LOCUS       DAVLTG010000126         1246 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLTG010000126 DAVLTG010000000
VERSION     DAVLTG010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.128"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..330
                     /locus_tag="VYN12_002091"
     CDS             <1..330
                     /locus_tag="VYN12_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEV1416382.1"
                     /translation="NSDGTTNAANVLSSGQLNVLAIAIFIAKNISQNSTVIDFIGIDD
                     PIQNMDDINQFSMIDVLSQLKKQLIFTTHDVKYVNLFLKKNELRLDDISVYYLDAEND
                     KYENILI"
     gene            701..1057
                     /locus_tag="VYN12_002092"
     CDS             701..1057
                     /locus_tag="VYN12_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416383.1"
                     /translation="MKRNIRSVRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQICRDVHEVLIISKSDHQVTQEHVSILLTCIQELIKEV
                     ENTSPLSEDFRNKYMR"
     gene            1062..>1246
                     /locus_tag="VYN12_002093"
     CDS             1062..>1246
                     /locus_tag="VYN12_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEV1416384.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLN
                     PGMNFITIDTNSYQDLI"
BASE COUNT          439 a          171 c          221 g          415 t
ORIGIN      
        1 aatagtgatg gaactactaa cgctgctaat gttttaagtt ctggacaact gaacgtatta
       61 gcaatcgcta tttttattgc gaagaatatt agtcagaata gcacagtgat tgattttatt
      121 ggtatagatg atcctattca aaatatggat gacattaatc agttctctat gattgatgtt
      181 ctcagtcaat taaagaagca actcattttc actacacatg atgtaaaata tgtaaatcta
      241 tttctgaaaa aaaatgaact tcgcttagac gatatttctg tatattattt ggatgctgaa
      301 aacgataaat atgagaatat tttaatttga gattagactc aatgatggat tatatgtatt
      361 tttagaattg agagtcaaga attattgacc ctctttttta tcatctcatt tccctgtgat
      421 aaaatttcca actttccttt gctatacttt tctcaacttg taaaaatcta tgttagattt
      481 tctatggggg tttgggggag gagccaccaa gttatcatat cgttagcttt caaaactaga
      541 aggttttgat cagctggcga tatgattttt aggatattgt ggacacaata tctgagctcg
      601 caaagcctta caaaatgttg aagctatttt gaaaaatgta ctgacagtgt ctgtaagctt
      661 acattgtcag tacaggtatc aatgaaggag gaaaagttat atgaaaagaa atatacgtag
      721 tgttcggaaa caatttcgct taacagaaac ggaggaaaaa caaatactag atttaatgag
      781 agagaaagga gaggataatt tttctgattt tctccgtaaa agcttactat tgtccgatgg
      841 acaaaaacag atggaaaaat ggttcaacct ttggaaaaaa caaaagttgg aacaaatttg
      901 tcgcgatgtt catgaagttt taatcatttc taaaagcgat catcaggtta ctcaagaaca
      961 tgtttctatt ttgttaactt gtattcagga attaattaaa gaggtagaaa ataccagtcc
     1021 tcttagtgaa gattttcgta acaaatacat gaggtagtag agtggagcac cgatatagaa
     1081 caaatttaaa aaaagtcttt ttatctgacc tagaattagt caaattgaat gaaaatatct
     1141 caaaaagtaa ctgcttatca ttctcagaat atgctagacg aactctacta aatcctggta
     1201 tgaattttat caccattgat acaaatagtt atcaagattt gatttt
//
LOCUS       DAVLTG010000127         1221 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLTG010000127 DAVLTG010000000
VERSION     DAVLTG010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.129"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..>1221)
                     /locus_tag="VYN12_002094"
     CDS             complement(<1..>1221)
                     /locus_tag="VYN12_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4297 domain-containing protein"
                     /protein_id="HEV1416385.1"
                     /translation="TEDKNNILNIDFSQSIDKLYAPINNEDIEDILLAEETSDDGGII
                     AMTGFYYQMMVAVLYLGEVFQGDWDGMFLDHHQDIVLFNNSKKIIKFIQVKTKNSTYA
                     PANKKIVESWIPKLFITAFNIKQKQDFNLKFELVSNCFFQDQKNFNISPFYPDSESRS
                     IEETKQMISASFGSKVINYNDNNEDFLDQAFENFNMRHIPHESLEEKVVRNIPISLGF
                     VNNQLSQDMLDHIISEFFKSCYNPEDASVQLISGERLNKLKGIIKKQLENSVVNAYHT
                     SSEKIFTDYLTKLDKEYSHPKMKSDFIKEFRIFLDRFDVEIKKTLSSSDLTMMGIINR
                     YLKYNESINVMLEESDRKEHFNDLFSLLLFLKISIESDIKIDEKNRHILSVNLDKLLF
                     LVLGNDDNFREPSE"
BASE COUNT          399 a          211 c          145 g          466 t
ORIGIN      
        1 atttctgaag gctccctaaa attatcgtca tttcctaaaa ccaaaaagag cagtttatct
       61 aaattaactg ataaaatgtg tctgtttttc tcgtcaatct ttatatcact ttcaatcgaa
      121 atcttgagga ataacaataa tgaaaacaag tcattaaaat gttccttacg gtcactctcc
      181 tctagcatta cattaatact ctcattgtat tttaaatacc tattgataat acccatcatt
      241 gttaaatcgc tagatgacaa agtctttttt atctcaacat caaacctatc caaaaatatt
      301 ctaaactcct taataaaatc tgacttcatt ttaggatgag aatattcttt gtccaatttt
      361 gttaagtaat ctgtgaaaat tttctcagaa cttgtatgat atgcatttac tactgagttt
      421 tctagttgct tttttataat tcctttgagt ttgtttaacc tttcaccact aattaattgt
      481 accgacgcat cttcagggtt gtaacatgat ttaaaaaact cggaaataat gtgatcaagc
      541 atatcttgcg atagttgatt gttcacaaaa cctaaactta ttggtatatt cctcactacc
      601 ttttcttcta atgattcatg aggtatatgt ctcatattaa agttttcaaa agcttggtcc
      661 agaaaatcct cattattatc attgtaatta ataactttcg aaccaaaaga agcactgatc
      721 atttgttttg tctcttcaat acttctactt tccgaatctg gataaaatgg tgaaatatta
      781 aaattttttt gatcttgaaa aaaacagtta gaaactaatt caaattttaa attgaagtct
      841 tgtttttgtt ttatattgaa cgcagttata aataatttgg gaatccagct ttctactatt
      901 tttttatttg caggtgcata ggtgctattt ttagttttca cttggataaa ttttattatt
      961 ttctttgaat tattaaacaa aacaatatct tggtgatgat ctaaaaacat cccatcccaa
     1021 tcaccttgga atacttctcc caaataaagt acagccacca tcatctgata ataaaatcct
     1081 gtcatagcaa taatcccacc atcatctgag gtctcctctg ctaaaagaat atcttcaata
     1141 tcctcattat ttattggagc atatagttta tcaatagatt gactaaaatc tatgtttagt
     1201 atattgtttt tatcctcagt a
//
LOCUS       DAVLTG010000128         1171 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLTG010000128 DAVLTG010000000
VERSION     DAVLTG010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.130"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            18..1019
                     /locus_tag="VYN12_002095"
     CDS             18..1019
                     /locus_tag="VYN12_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1416386.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT          386 a          145 c          230 g          410 t
ORIGIN      
        1 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg gggggagaat
      601 cccatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
      841 ttattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatgaagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aacaagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc g
//
LOCUS       DAVLTG010000129         1147 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLTG010000129 DAVLTG010000000
VERSION     DAVLTG010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.131"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            10..744
                     /locus_tag="VYN12_002096"
     CDS             10..744
                     /locus_tag="VYN12_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416387.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            904..>1147
                     /locus_tag="VYN12_002097"
     CDS             904..>1147
                     /locus_tag="VYN12_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416388.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLNFIVAIVVNTILLVLFYFLLSYIFYLYKLKSG"
BASE COUNT          418 a          125 c          202 g          402 t
ORIGIN      
        1 ttaaaattaa tgagaatcaa agagaaaacc aataatatta atggaggaat aaaaaatgta
       61 agtaagcatt atggtcattc aatcattctc aaagatataa attttgcact taacaagggt
      121 gaaattgttg gtctagcagg gagaaatgga gttggtaaga gtacgttgat gaaaattctt
      181 gttcagaata atcaaccgac ttcaggtaat attataagca gtgataatgt tgggtattta
      241 atcgaagaac caaaattatt tttatctaaa acaggtttag agaatttaaa atatttgtca
      301 aatttatatg gtgttgacta caatcaagaa agatttagat gtttgatcca agagttagat
      361 ttgactcagt ctattaataa aaaagtaaag acctattctt tgggtacaaa acaaaaatta
      421 gctttgcttc taactctcgt tacggaacct gatatattga ttttagatga accgactaat
      481 ggtttagata ttgaatcatc acaaatagtt ttagcggttc taaaaaaatt agctttacat
      541 gaaaatgtgg gaattttaat atcgagtcat aaattagaag acattgaaga aatttgtgag
      601 agagttcttt tcttggagaa cgggcttttg acatttcaaa aagtaggaaa agatagtcat
      661 aatttcttgt ttgagatagc tttttcatca gctacagata gagacatttt cattaccaaa
      721 caagaatttt gggatattgt ttaggaagag ggattgagaa ttactatgtc tgggaatatt
      781 caaaatagtg agctttttaa attttttaac gaaaactcta ttaaagtagt tgattttgaa
      841 actaaaaaag agacgcttaa agatatttac ctaaatcgtt caaaataaag gaaggttata
      901 atcatgaaat taaataaaca gaagaatcgg atgatttacg tcttgtctaa ttttctatat
      961 gctatctcag tttccattat ttatgctttg aatggcattg tgttactagt catagtaagt
     1021 aaattgggta ttccaggtga tttaggatta aattttatag tagctattgt agtcaataca
     1081 attttgttag tcctgtttta ttttctatta tcttacattt tctatttata caaattgaaa
     1141 agtggct
//
LOCUS       DAVLTG010000130         1088 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLTG010000130 DAVLTG010000000
VERSION     DAVLTG010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.132"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..191
                     /locus_tag="VYN12_002098"
     CDS             <1..191
                     /locus_tag="VYN12_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416389.1"
                     /translation="FINMAEHKIDNDGVKGHSYSPSVQIQDLYKNLMAKDGDRKKLSK
                     SKISETLKELKFLGENDD"
     gene            181..>1088
                     /locus_tag="VYN12_002099"
     CDS             181..>1088
                     /locus_tag="VYN12_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1416390.1"
                     /translation="MMIRLKQVIIKNFRNFQGTHQFDFSKDVTIFLGDNGNGKSSVFD
                     AIQWCLTGNVERFKNVSSADIMKSVLINKNSDECAVEIIFTTNLSLKRVAPRYGNIRV
                     SCNYGNEIVRGDKNVKEYIEGLFKNSKGEKFDIQEFLKSSLLAQDQVLDFISSDTAND
                     RYRVLSSILGMNEITNLKENYEKVRSLLDNEMEKKADFVKSLQKEIDLQESKIDYGYK
                     YLITDEISNSSFEDKQKENNELQKSKAQIEERLTRFNLQYNNIKQDIGDLNQIANTIK
                     SLEYEIKELQIAQEKNLKDSALNDNL"
BASE COUNT          446 a          115 c          202 g          325 t
ORIGIN      
        1 cgtttataaa tatggcagaa cataaaatag ataacgatgg agtaaagggg catagctatt
       61 cgccttcagt acagattcaa gatttgtata aaaatttaat ggcaaaagat ggggatagaa
      121 aaaaattatc gaaatctaag atatccgaaa ctttaaaaga gttaaaattt ttaggagaaa
      181 atgatgatta gattgaagca agtaataatt aaaaatttta gaaattttca aggtacacat
      241 cagtttgatt tttcaaaaga tgttactatc tttttaggag ataatggaaa tgggaaaagt
      301 tcagtttttg atgcaattca atggtgttta acaggaaatg ttgaaagatt caagaatgtc
      361 agtagtgcag acatcatgaa aagtgtacta ataaataaga actctgatga atgtgcagtt
      421 gaaattatct ttacaactaa tttatctttg aaaagggtag caccaagata tggtaatatt
      481 agagtttctt gtaattatgg caatgaaatt gtacgaggag ataaaaatgt caaagaatat
      541 atcgagggat tattcaagaa ttcaaaaggt gaaaaatttg atattcaaga atttctgaag
      601 tcctctttac ttgctcaaga tcaggtgtta gatttcattt caagtgacac tgcgaacgat
      661 cgttataggg tactatcttc gatactagga atgaatgaaa taactaactt aaaagagaat
      721 tacgaaaagg ttaggagttt gctggataat gaaatggaga aaaaagcaga ttttgtgaaa
      781 tctcttcaaa aggaaattga tcttcaagaa tcaaaaattg actatggata taaatatctg
      841 attactgatg aaataagtaa ttctagtttc gaggataaac aaaaagaaaa taatgagcta
      901 cagaaaagta aagctcagat tgaagagaga cttacacgat ttaatttgca gtataataat
      961 attaaacagg atattggtga tctaaatcag attgctaaca caattaaatc actagaatat
     1021 gagataaaag aacttcaaat cgctcaagaa aaaaacttaa aagattctgc cttgaatgat
     1081 aatttatt
//
LOCUS       DAVLTG010000131         1050 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLTG010000131 DAVLTG010000000
VERSION     DAVLTG010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.133"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..559
                     /locus_tag="VYN12_002100"
     CDS             <1..559
                     /locus_tag="VYN12_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1416391.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..1049)
                     /locus_tag="VYN12_002101"
     CDS             complement(507..1049)
                     /locus_tag="VYN12_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1416392.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINKGVRIIRGGNIKPLEF
                     SLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIFQ
                     LTPFESSDIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFEE
                     QELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          352 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccagaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cttgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctata aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataata
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtgtc aatgtagtaa
      901 tcattatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattaa tgcttaaatc gcccttcttg taagaaagac ctgtatttat tgaaaaaata
     1021 tcttttattt ttataacaac ccaattcata
//
LOCUS       DAVLTG010000132          956 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLTG010000132 DAVLTG010000000
VERSION     DAVLTG010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.134"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..935)
                     /locus_tag="VYN12_002102"
     CDS             complement(<1..935)
                     /locus_tag="VYN12_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1416393.1"
                     /translation="MVAGQLLLIYAATINALVLNELIAMNLERFLKLSIYQMIVWCGI
                     IFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLN
                     DQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFASKMREVSL
                     NLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAG
                     AISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGGQLSSIIG
                     TKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEA"
BASE COUNT          342 a          172 c          129 g          313 t
ORIGIN      
        1 gcttcatata acggaaaatc tctattcacc tcatttggtt cgatatcatt cattttattt
       61 gactcaattg gattaattga atacaatttt aaaaaaatag gcttcgtacc aataatagag
      121 gataattgac ctcctaattc acctagcgct gtaaaaataa cacctgttag tgctcctatt
      181 gcttcaatag taccaatttt cactattcct tttattgcaa gatagcctgt taaaaaaacg
      241 agagatatct gaaaaaaaat attgagaaag aagctaatag cgcctgctaa cgtttctaca
      301 gttgtctttc tttgtataac catctttaat aaaattcctg cttctttaat tttcttaggc
      361 aatacatata aaagattcaa ggacgctaac acatcaaatc cattcaatat agtctcacta
      421 gattttaaaa aagcttcatt ttggctagtt aaatttagac taacttctcg cattttcgat
      481 gcaaagattt ttggtacaag tagcataatc attaatgaaa acaaggtggc tacagtcaat
      541 gaccaatgat agtgattaag agtcacaact gcaaatatag taccagaaat tccttttatt
      601 actaaaaaaa gttgtttaaa agcctgatca tttaaagtct gaacatcatt atttagccac
      661 gaaagatatg ttcctgatga tttactatga aattcttgat aggtagagtt agagatgtct
      721 gtggcaactc tatttcgaat ctctagatta aactcttgga tcacttcaac ctgataattt
      781 ttcactaccc agtcaaggaa tattatccca caccagacaa tcatttggta gattgacaat
      841 ttcaaaaacc gctctaaatt catcgcaatt aattcattca acaccagagc attaatagtt
      901 gctgcataaa ttagcaataa ttgaccagca acaataaata tcgttaataa actaaa
//
LOCUS       DAVLTG010000133          954 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLTG010000133 DAVLTG010000000
VERSION     DAVLTG010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.135"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..293)
                     /locus_tag="VYN12_002103"
     CDS             complement(<1..293)
                     /locus_tag="VYN12_002103"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV1416394.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNV"
     gene            complement(283..>954)
                     /locus_tag="VYN12_002104"
     CDS             complement(283..>954)
                     /locus_tag="VYN12_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV1416395.1"
                     /translation="KLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETF
                     NNIRVLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDI
                     LQLLSDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEF
                     LCDLLLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIR
                     PHYGS"
BASE COUNT          337 a          163 c          124 g          330 t
ORIGIN      
        1 tctacattat cctctatacg ttttaatcct aaatttaaac cttgtttatg agtcggtaat
       61 aaaataatag caggcacaac ttgggaatca taatggcgaa ttgtatctaa tatcattgaa
      121 gcaatgtctt cagtgatata aatgacacca taatcagatt gagctaattt tcttagtgta
      181 tttatagctt cttgttcttg gtaggcagga aatatatcaa acccaatcat gctaaatggt
      241 aaaataatat cacggctacc aattatgcca attttatact tattagcttc cataatgtgg
      301 gcgtatcctt tcttttattg attcaaaggg aattgtattt tgaagagctg atatgatcat
      361 tctgagattc tttacttcaa actcacatcc caataaatat ctagcaagaa ctaacggccc
      421 ctctacattg taccttcctt gatctaaagt tttatacaat agtaaatcac ataaaaattc
      481 taactcagaa gatgaaattg ttgcgtcctg catcttcaat tcataagttg aaaagattga
      541 atctaagctt ggatttattt tattgaacca cacaaatatt tcttgatttt ctacaatgta
      601 tataaattct ttagcagaaa tacttccttc atctgaaagt aattgtaaaa tatccccatg
      661 actcttattt tgagataaac cacgttttac agtaataata ttataaaagt caatcatttc
      721 gacaataacc tgagacagta cctcatctaa ctcattagat aaaagtttca gatgtttaaa
      781 atatgctaga tcagctccga catcaagtac acgaatatta ttaaaagttt catactcatt
      841 ccaaattgat tctacttcac gaaccataaa atcaggaagt gtatctgaat gtaaggaaga
      901 aactaaatgt tttaaacttt ctatatcaaa aatccctatt ggaattaata attt
//
LOCUS       DAVLTG010000134          928 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLTG010000134 DAVLTG010000000
VERSION     DAVLTG010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.136"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            43..351
                     /locus_tag="VYN12_002105"
                     /pseudo
     CDS             43..351
                     /locus_tag="VYN12_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(506..829)
                     /gene="tnpB"
                     /locus_tag="VYN12_002106"
     CDS             complement(506..829)
                     /gene="tnpB"
                     /locus_tag="VYN12_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1416396.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          317 a          170 c          178 g          263 t
ORIGIN      
        1 aagctgagcc aaagttatgc gctaaagggg ctttaggaat aggagatttc acaagcttat
       61 ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc aagtacctta
      121 aagattccga ctaatattgg ctttgcattt attcctccat acacaccaga gatgaacccc
      181 attgaacaag tgtggaaaga gattcgtaaa cgtggattta agaataaagc cttttaaact
      241 ttggaagatg tcatgaatca actccaagat gttatacaag gactggagaa ggaggtgata
      301 aagtccatcg ttaatcggag atggactaga atgctttttg aaagcagatg agtataaaaa
      361 gaaagtcctc atttcaatag aaatcacgac tttctgatgg atttatagta aaatgaaata
      421 agaacaggac aaatcgatca ggacagtaaa atcgatttct aacaatgttt tagaagcaga
      481 ggtgtactat tctagtttca atctactata tttttggagt gatagaaaag cccttcataa
      541 gccagtctac ttgttctggt gtgagagctt tgacatcctt ttctgtactt agccaaatca
      601 atctgccgtt ctcaaagcgt ttatatagta gccaaaatcc ttgaccatcc cagtaaagga
      661 ctttaaagcg gtctttacgt ccaccacaaa agagaaagac ttgaccggag aaaggatcca
      721 attcaaagtg ggttttaacc agataagcca gtgaatcgat tccttgtctc atatcagttt
      781 tcccacacac gagatagacc tcccctaggc tagatagatg aattgtcata gagcaacacc
      841 ttatccaaaa gctgttctac catttcgaga ttgagagatt gaaaaaaact tacttcaagc
      901 ttgccaatac gaattttaag cagaatat
//
LOCUS       DAVLTG010000135          905 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLTG010000135 DAVLTG010000000
VERSION     DAVLTG010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.137"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            1..905
                     /locus_tag="VYN12_002107"
                     /pseudo
     CDS             1..905
                     /locus_tag="VYN12_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
BASE COUNT          342 a          103 c          162 g          298 t
ORIGIN      
        1 gacagattat gatgagaaaa ttggtagttt taatacatat gaaatcgaac aaacggtatc
       61 gaagattctg agggtaaaac ctaatggaaa gattatttta aagtcaacag ttccgatcgg
      121 cttttcaaac aaattaaaaa ggctgtttga tacaaaaaat atcatttttg tccctgaatt
      181 tttgagagaa ggttgttcta tatatgataa tttatatcca agtcgcatag ttgttggaga
      241 tgagacagtt gaaggaagaa aaattgcaga gttgttcctt tcgattagta ctcatagtac
      301 tgccaatatt aaaaatgtta tgttagtttc tcctactgaa gcagaagcaa ttaagctttt
      361 ttctaacaca ttcttagctc tccgtgttgc tttttttaat gaactagatt cttttgctga
      421 gaggagaagt ttaaatgctg aagttgtaat aaaaggtgtt tgtttagatc caagaattgg
      481 aaatttttat aataatcctt cttttggatt tggaggatat tgtcttccca aagatactaa
      541 acaattaaaa aaagaattta tagaaataaa tgccccagtg atagaagcga ttgatatttc
      601 aaacacaaat agaaaacagt tcatagttaa acaaatattg gaacgaaagc caaagatagt
      661 aggaatatat aaattgggga tgaaatataa ttcagataat tacaaagagt cagctatttt
      721 aagtataatt aatgaactat tgattgtcgg tataaaaatt ttagtatatg aaccaaattt
      781 aaacgttagt tatagataac gtaatttttg aaaagaattt tgaactattt acaaaacaaa
      841 gtgatctaat tgttgcaaat agatgggata ggggccttga agcttataaa gataaagttt
      901 acaca
//
LOCUS       DAVLTG010000136          903 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLTG010000136 DAVLTG010000000
VERSION     DAVLTG010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.138"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            92..274
                     /locus_tag="VYN12_002108"
     CDS             92..274
                     /locus_tag="VYN12_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1416397.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            284..634
                     /locus_tag="VYN12_002109"
     CDS             284..634
                     /locus_tag="VYN12_002109"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1416398.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            642..>903
                     /locus_tag="VYN12_002110"
     CDS             642..>903
                     /locus_tag="VYN12_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1416399.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIAN"
BASE COUNT          373 a          114 c          153 g          263 t
ORIGIN      
        1 gaaatgaccg aattagaaag aaaaaatcga aaaattagct aagaaatatt ctgataactt
       61 aaacatcaaa gttcaagaga gagttcgtga aatggcaaat gataataaga gccattattt
      121 gatatacaga gttttaggta tttcatttga agaaggagaa aatatcgatt tgtatcaaaa
      181 taaaggtcgt tttttataca aatatgctgg ttcattttta gaagaagctg cagtactatc
      241 ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt aacattccta attctgaaag
      301 tacaaaacct aagacttttg aaattgattg tttagtcgga gaaaaacacg catacgaaat
      361 aaaatggtgg gatgcaacta cagatggaga ccatataact aaagaacaca ctagaataaa
      421 agttattcat aacaaaggat atataccaat tcggttaatg ttctactatc caaatagaac
      481 tcaagctata aaaattcagc aaactttaga aacattgtat aacggtattg gagggaaata
      541 ttatggagat tctgcctggg aagatttaag agcagtgacc ggtattgatt tacttagtat
      601 tctaacagat attgcaaata aaaaacaggg gtaaaatcaa aatgacagta ttaaaaggag
      661 ataacttaga aatattaaaa actattgaat cctcaagtat tgatttaatc tatatggacc
      721 ctcctttctt tacacagaaa acccaaaaat tatctaataa caaaaatatt atgtattcat
      781 tcgaagatac gtggacttcg attgaggatt acaaagaatt tttgtctgta agattagaag
      841 aatgcaaaag agtgctaaaa aatagtggca gtattttcgt tcattgtgat aaaattgcaa
      901 atc
//
LOCUS       DAVLTG010000137          817 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLTG010000137 DAVLTG010000000
VERSION     DAVLTG010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.139"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..601)
                     /locus_tag="VYN12_002111"
     CDS             complement(<1..601)
                     /locus_tag="VYN12_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1416400.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHIDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEK"
     gene            complement(613..816)
                     /locus_tag="VYN12_002112"
     CDS             complement(613..816)
                     /locus_tag="VYN12_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416401.1"
                     /translation="MKSLSFLSKIVNGLIQNIEENLEDDIERILKYLYICLFNEIFII
                     KNKVNFFDDVEFNQTLSEFLDKL"
BASE COUNT          282 a          159 c           88 g          288 t
ORIGIN      
        1 gtttttcatc aagttcctct tgatacattt ttaattcttt agtttttccc atataactaa
       61 ccatactact atcacttaca tatgggaagt cctcataata tattacttta taacgcataa
      121 attcaagcgc ccttccaata ctattcacaa aaacatgatc aatatggtca ccaagtgaaa
      181 gcggacaata tacgacacat ttgtcatcta aatgcattaa cagctctttt atgatatcat
      241 tctttaatgt gtcctcattt tttaattcac tatagatatg acggtataga aaattgccat
      301 ttctatcttt cctatagaga cattcatagt acgataagtg tctaaaatca cactgtagac
      361 gttcacaagc taacctgtct tctttcttcc tttcttcaat cggatatttc ccaaggttac
      421 acaacttatg aaattgctta gcagagggct gtagctgttg gctcaaaggg taaccagaaa
      481 atatagtaat aacaagtaca atttctcctt ctgaagttaa ttttgaaata taatcaccac
      541 aggaaaaaat tgcgtcatct aaatgtggag ataaaaagat atacttagta ttgttactca
      601 taaccattcc ctctacaatt tatctaaaaa ttcactaagt gtctgattaa attccacatc
      661 atcaaaaaaa ttcaccttat tcttaataat gaatatttcg ttaaataaac atatatataa
      721 atatttcaat atcctttcaa tatcatcctc taaattctcc tcaatatttt gtatcagccc
      781 atttacaatc ttacttaaaa aagataagct ctttatc
//
LOCUS       DAVLTG010000138          788 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLTG010000138 DAVLTG010000000
VERSION     DAVLTG010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.140"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(43..189)
                     /locus_tag="VYN12_002113"
     CDS             complement(43..189)
                     /locus_tag="VYN12_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416402.1"
                     /translation="MKTKEQTRKLAAGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FKEY"
     gene            347..565
                     /locus_tag="VYN12_002114"
     CDS             347..565
                     /locus_tag="VYN12_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1416403.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
BASE COUNT          251 a          116 c          146 g          275 t
ORIGIN      
        1 cgaaatctag tggaatgaat ctggaatagt ccatcgagct ttctaatact ctttgaaaat
       61 ctcttcaaac cacgtcaacg tcgccttgcc gtgcgtatgg ttactgactt cgtcagttct
      121 atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag tttgctcttt
      181 ggttttcatt gagtataaca cattgttaga agttggttta aatttcctaa tcagtttgtt
      241 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      301 ccatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaaaaatatc
      361 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      421 cgtaaatggt actgctattc tttatcctta tttacgttct attgtttcaa tagtttcggc
      481 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      541 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      601 aaaagcagta agaaaaatgt cttgcattat acagcaactt tttgggaatg agtagatgga
      661 ttgaataaaa tttgattaag agtggatgat ttatctgtag attattattg gacagttagt
      721 cttgaagtag tctaagaatt aggttataat cagtagaagc cttgctaata atgaggaggt
      781 tagtttat
//
LOCUS       DAVLTG010000139          759 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLTG010000139 DAVLTG010000000
VERSION     DAVLTG010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.141"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..380
                     /locus_tag="VYN12_002115"
     CDS             <1..380
                     /locus_tag="VYN12_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1416404.1"
                     /translation="EGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGD
                     DGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIV
                     THAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          274 a           90 c          145 g          250 t
ORIGIN      
        1 ttgaaggtac gattagagat aatattttat tggaagaaaa ttatactgat gaagaaatac
       61 tacagtcttt agagcaagtt ggtttgagtg taaaagattt tcctaataac attttagatt
      121 attatgttgg tgatgatggg agattactgt caggagggca gaaacaaaaa attactttag
      181 ctagagggct aattagaaat aagaaaatag tattaattga cgagggaact tctgctatcg
      241 ataggagaac ttcgttagcg attgaacgta agatattaga tagagaggat ttgactgtca
      301 ttattgttac ccatgctccg catccggaac ttaaacaata ttttactaag atatatcaat
      361 ttccaaagga ttttatttaa gaatataggg gagggaaaca tgagattcta ttgtgaaact
      421 tatgaggtaa ttactgaaga gaaaaaagta tcattttttt atgtagatga gaaaccctta
      481 aggtatctgt tatttgacta tatatttcta ctagttctag ctaaaaaaaa tatcccaatc
      541 ttatgaactg caccccaaaa gttagattta ttctgtctaa cttttggggt gcagttcatt
      601 ttgcatagtt ttggcattca tcctagatat ccatataaaa tgtctgagat tgttgaaatg
      661 tctaaaaaaa tatcagatct aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg
      721 aggtttcaag atagtgttct tgataacata aatagtgtc
//
LOCUS       DAVLTG010000140          755 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLTG010000140 DAVLTG010000000
VERSION     DAVLTG010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.142"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..>755
                     /locus_tag="VYN12_002116"
     CDS             <1..>755
                     /locus_tag="VYN12_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1416405.1"
                     /translation="MMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSIST
                     STVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAI
                     IRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRV
                     RVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSY
                     SQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNL"
BASE COUNT          236 a          153 c          124 g          242 t
ORIGIN      
        1 atgatggtcg ctgaaacttc tatcgtcaag aagaatcacc aaatccctcg tatcatcaac
       61 caaaaaattg ctcaaaagtt aattgaaaaa atttctatga ctgatattgc ccatcagctt
      121 tccatctcaa cttcaactgt tattcgtaag ctcaatgatt ttcactttaa acatgatttt
      181 tcttgtcttc ctgagattat gtcttgggat gagtatgctt ttacaaaggg aaagatgagc
      241 ttcattgcgc aagattttaa caatctcaat atcatcactg ttcttgaggg aagaacacaa
      301 gctatcattc gaaatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatt
      361 attactatgg atatgtttag tccttactat gacttagcta gacaactttt cccatgtgct
      421 aaaatcgtgt tggatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
      481 cgtgttcaaa tcatgaatca attggatcga aagtctcatg aatacaaggc tatcaagcgc
      541 tactggaagc tcatacaaca ggatagtcgt aaactcagcg ataaacattt ttatcgtcct
      601 acttttcgta tgcacttaac caataaagag attttaaaca agcttttgag ctattcacaa
      661 gacttgaaac atcactatca gctctatcaa ctcttgctgt ttcactttca gaataaggaa
      721 ccggagaaat ttttcggact cattgaggac aatct
//
LOCUS       DAVLTG010000141          752 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLTG010000141 DAVLTG010000000
VERSION     DAVLTG010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.143"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..>752
                     /locus_tag="VYN12_002117"
     CDS             <1..>752
                     /locus_tag="VYN12_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1416406.1"
                     /translation="PLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVH
                     ADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLI
                     DKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNL
                     WDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDE
                     ILTKDSTVQRGEVLEDAQIKEKKATFVSKNTI"
BASE COUNT          278 a           98 c          160 g          216 t
ORIGIN      
        1 aaccattatt tggggaatta aatggtgcta cagtagaaaa actttcacta aaagatgtta
       61 atatttccgc aaaggacgat actgcaacac ttgcgaaaga agcaaataac aatactcata
      121 ttgataacgt tcatgctgat ggagcgatag ctggggaacg tagcatagga ggattagtat
      181 cacaagttaa taattctact atttctaaca gtagctatac aggtagaata actaatacat
      241 ataaaacagt tgctagttat caaatcggag gtttagtagg caaactttct ggtccgaggg
      301 gattaataga taagtcgttc gcatcaatcg atttatcttc aaatgcaaca caaggagacc
      361 agtctattgg tggaatagtt ggtgcagtag aaaatagtgc gcttattagt aatagttatg
      421 ctgaaggaaa tctaaataat gttcaacgtt ttgcaaacgt tggtggagta gttggtaatc
      481 tttgggatcc ggttggagga ttagaaaaat ccggtcgact ttctaatgta ctaagcgatg
      541 ttaatgtaac gaatggtaat gctattgcag gttataattt taatggtata aaagcaaatg
      601 gcacatacag taataaaaat aataaggttg tgaacgtagt acaagaagat gatgaaatct
      661 taactaagga ttctactgtt caaagaggag aagtattaga agatgcacaa ataaaagaga
      721 aaaaagctac ttttgtatct aaaaatacta tt
//
LOCUS       DAVLTG010000142          678 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLTG010000142 DAVLTG010000000
VERSION     DAVLTG010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.144"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..496)
                     /locus_tag="VYN12_002118"
     CDS             complement(<1..496)
                     /locus_tag="VYN12_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1416407.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNS"
     gene            576..638
                     /locus_tag="VYN12_002119"
     CDS             576..638
                     /locus_tag="VYN12_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEV1416408.1"
                     /translation="MKKISKFLPILVLVMDIIII"
BASE COUNT          233 a           91 c          111 g          243 t
ORIGIN      
        1 aggagttgta gttaattgtg cgtacacagt tacctaataa aatgatttca taatagcccc
       61 atttttcaac tttgaaaaga tagtctgtca gatgaagaag ctcttcatct gatggaatga
      121 tgttcgaatc cattgtgtgt aaaatagatt ttaccattgt tttctcaaaa gaatttagag
      181 tgtaatcaga agtatcagaa agtagacatg ctatattatt gatactttgt gatgaatatt
      241 gcttacgaat gtactgtact agattagcaa atgattcgga actggtatag tcgtcattgt
      301 gtaaaacaag gaactcatcc aaagtaatat gtaatttgtc taaaatattg attagtcgaa
      361 tacaagatat ctctgactcc ccacgttcaa aacgagatat ttgtgatttt gaaagatgtt
      421 catctgctac agagcataga ctaatttgtt ttcctttacg aacttttcta agtgtgatgc
      481 caagttttga tttcataatt tcccattttc ccaacaaaaa ttaaatccgt ttttatttat
      541 tgtacaataa ataaaaacgg aaaggaagtc caagtatgaa gaaaatttca aaatttttac
      601 cgattttggt tttggtgatg gatattatca tcatttaaaa aagtgtatta attattgtat
      661 ttcacaatta gataatat
//
LOCUS       DAVLTG010000143          660 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLTG010000143 DAVLTG010000000
VERSION     DAVLTG010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.145"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..>660
                     /locus_tag="VYN12_002120"
     CDS             <1..>660
                     /locus_tag="VYN12_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1416409.1"
                     /translation="SKTKNLTLVSDFGMRNYLDFPSYKELVKMYNDNFLSNDTLYEFR
                     HDRQEVNQRKIHSHHIIQSFSPDDHLTPEQINRIGYETVKELTGGRFRFIVATHVDKD
                     HIHNHIILNSIDQNSDKKFMWDYKAEHNLRMVSDRLSKIAGAKIIENRYSHRQYEVYR
                     KTNYKYEIKQRVYFLIENSKNFEDLKKKARALNLKIDFRHKHATFFMTDSTMKQVVRD
                     NK"
BASE COUNT          254 a           97 c          104 g          205 t
ORIGIN      
        1 agtaaaacaa aaaatctaac actagtttca gattttggta tgagaaatta tttagatttt
       61 cctagttata aagaactagt gaagatgtac aatgataatt ttttaagtaa tgatactctt
      121 tatgaatttc gtcatgatag acaagaagta aatcaacgaa aaattcattc tcatcacatc
      181 attcagtcct tttctccaga tgaccatctc actcctgaac aaatcaatcg aattggttat
      241 gagacagtta aagagttgac aggaggaaga tttcgtttta ttgtagcaac tcatgtcgat
      301 aaagatcata tccacaatca catcatccta aattcaattg atcagaattc tgataaaaag
      361 tttatgtggg attataaggc agaacataat ctacgaatgg tttctgatcg tctttcaaaa
      421 attgcagggg caaaaattat agaaaatcgt tattcgcatc gtcagtatga agtttatcgc
      481 aaaacaaatt acaaatatga aataaaacaa cgagtatatt ttctaatcga gaactcgaaa
      541 aattttgaag atcttaagaa aaaagctaga gctttaaatt taaaaattga ttttagacac
      601 aagcatgcca ccttttttat gacggattca actatgaaac aggtggtgcg tgataataaa
//
LOCUS       DAVLTG010000144          658 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLTG010000144 DAVLTG010000000
VERSION     DAVLTG010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.146"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            <1..>658
                     /locus_tag="VYN12_002121"
     CDS             <1..>658
                     /locus_tag="VYN12_002121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEV1416410.1"
                     /translation="IDIKNKLSNSNFDGLTFETDKDIQKKIEDLKGQVEKYQYALSHI
                     VNYYNLINDKEQIPKSIDEFNQKNEKLEGEIQVLQDRVVELKSDFSTVESKNDIDSLI
                     QLVQEAYKFVSDHKEFENTCPVCSQSVKNTTKHFDERITNLLEQSNITAEKISGFRKR
                     INETESSILNKQEEVRTIQLDISKLKYQENEIQTKLDIILGDYLYVKDNFTLDKEQLE
                     Y"
BASE COUNT          275 a           80 c          114 g          189 t
ORIGIN      
        1 tatagatata aaaaataagt tatctaattc taactttgac ggattaactt ttgaaacgga
       61 taaagatata caaaagaaga ttgaggattt aaaggggcag gttgaaaagt atcaatatgc
      121 tttgtctcat attgttaact attacaattt aataaacgat aaggaacaaa ttccaaaatc
      181 tattgacgag tttaatcaaa aaaatgaaaa attagaaggc gaaatccaag tattacaaga
      241 tagggtagtt gaattaaagt cagattttag cacagttgaa tcaaagaatg atattgactc
      301 actgattcaa ttagttcaag aggcatataa atttgtgagt gaccataagg aatttgagaa
      361 tacttgcccg gtttgcagtc agtccgttaa aaataccacc aaacattttg atgagcgtat
      421 tactaatcta ttggaacaaa gtaacattac agctgaaaaa attagtgggt ttaggaaacg
      481 aataaacgag actgaatcaa gcattttgaa taaacaagaa gaagttcgta caattcaatt
      541 agatatatcc aaattaaaat atcaagagaa cgaaatccag acaaaactag acattatatt
      601 gggtgattat ctatatgtta aagacaactt tacattagat aaagaacagt tggagtat
//
LOCUS       DAVLTG010000145          631 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLTG010000145 DAVLTG010000000
VERSION     DAVLTG010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.147"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(35..205)
                     /locus_tag="VYN12_002122"
     CDS             complement(35..205)
                     /locus_tag="VYN12_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416411.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(218..>631)
                     /locus_tag="VYN12_002123"
     CDS             complement(218..>631)
                     /locus_tag="VYN12_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1416412.1"
                     /translation="KNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQ
                     RQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIVAHRLSTIKDA
                     DVIFVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT          190 a          140 c           69 g          232 t
ORIGIN      
        1 tctctactcc ttagtttaca gcaaaaaatt atgcttaatt cttattgttt ttgtaaacaa
       61 tcagcgaacc caatactatt ccattcaaca agcctaaaga aataccatat tcaactggaa
      121 aatctaaaaa aattgcaaac actattccaa tcatcacccc tagtgaggct gttgttaaaa
      181 ttacatattc attttctttc ttcattttct ttacacctca tttccttttt gtatataagc
      241 tgtagtactc tccaccaaga tccattaagt acttatgatt tcctgactca acaatcttac
      301 cacctttcat tacaaaaata acatccgcat ccttaatcgt tgacaatcta tgagctacaa
      361 ttatttgagt acagccctga ctttgtatat actttgttat tctttcctca ttaatagtgt
      421 ctaatgcact agttgcttca tctaaaatta caatactagg attatttatt aatgcacgtg
      481 ccagtgctat ccgttgcctt tgcccacctg aaatatttga ccccatctct gagatgatag
      541 tattaaattt catcggcata gccatgattt catcatagat ttgaactgct ttacaaactt
      601 cctctatctt ttgtgaagta acttcgttct t
//
LOCUS       DAVLTG010000146          624 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLTG010000146 DAVLTG010000000
VERSION     DAVLTG010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.148"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..590)
                     /locus_tag="VYN12_002124"
     CDS             complement(<1..590)
                     /locus_tag="VYN12_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1416413.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWIS"
BASE COUNT          217 a          109 c           75 g          223 t
ORIGIN      
        1 atacttatcc attcatttgc ctttgcttta aagaaaaaat cagcggcagg agcgtccatc
       61 ttacaattta atatttccat tgccactctt tctaaggcct ttgtaagtat tatttgattc
      121 gattgaagca aggttgaata aaaagattct ggattaatgt taatagatgc taaatgtttt
      181 tctattagct cttttttaaa accaatggaa acagcaagat aacaacaatt ctcgtgtaat
      241 aaaaaaacaa aatcatcttt tatattatca aaatcaaaag tacataaaga gtttgcggta
      301 atagtttgat acggattaaa cttttctccg tttgcactga caatgtaact tgaataaatt
      361 gaaacatagt ctgacatact ataagtgcta ttttgaacta cttcctcttt gatataaaaa
      421 tcatgtatat cgataatgaa gctgcctcct tcataaaacc aatataggcc ttctgcataa
      481 gttgaattct cttttttcca acaaaatgta tgacctgcac ttgaatactt ctcattgttt
      541 ttacattcat ctactttcat ataatctttt acaaaatcat aatatgacat aacacactat
      601 cccttttaga caatattcca atta
//
LOCUS       DAVLTG010000147          582 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLTG010000147 DAVLTG010000000
VERSION     DAVLTG010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.149"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            29..310
                     /locus_tag="VYN12_002125"
     CDS             29..310
                     /locus_tag="VYN12_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416414.1"
                     /translation="MRELNLCHGSVGTISCLDAILKDEENLLIKESIDFYFDNVVSQV
                     IKPELSTDLNTMNTFSFMLGVSGVVYEISRKQDDRLLNVLLLELRGHDD"
     gene            303..>582
                     /locus_tag="VYN12_002126"
     CDS             303..>582
                     /locus_tag="VYN12_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416415.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVV"
BASE COUNT          218 a           64 c          106 g          194 t
ORIGIN      
        1 taaaaatgta ttaactaatg tagaaaaaat aagagaattg aatttatgtc acggttctgt
       61 aggtactatc agttgtcttg atgcaatatt gaaagatgaa gaaaacctat taataaaaga
      121 atctatagat ttttattttg ataatgtcgt ttctcaggtc atcaaaccag aattaagtac
      181 ggatttgaat actatgaata cattttcttt tatgctagga gtatctggag ttgtctatga
      241 aatatctcga aaacaagatg atagattact taatgtttta ttactggagt taagaggaca
      301 tgatgactag aaaagtacct aatattgagc aaatgtctca aatagaatgt ggtttatgtt
      361 gctgcttgtc catactacat ttctataaaa gcaaagagac attactagat ttaagacgtg
      421 atatagaaaa agggagagat ggttatagta taggtgactt gaaacagtta ttgaataaac
      481 gaaattttga tactggctca tatcaagtta aagatgtaaa taaaattagt gaacttccgt
      541 taccattaat agcattctgg gataatcaac attatgtagt ta
//
LOCUS       DAVLTG010000148          560 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLTG010000148 DAVLTG010000000
VERSION     DAVLTG010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.150"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
BASE COUNT          183 a           75 c           89 g          213 t
ORIGIN      
        1 tggataaaaa aataaaggca gtccgaagac cgccaatatt tatctctctg cacctttgct
       61 atggtctttc ttatttgact tagatttgtc atctgtctta aagcttttta tttgccctaa
      121 tatggacttt ttatccttgt cttgactctt tacttgttct tttgctttta agagcttaga
      181 agacaaaaag agatattata ttaaaacaat atttctccgg tactgggact gggacgggac
      241 taaaaatctg aaaacgtcct ataattaggt ggatttagtg atattataaa aaatagaatc
      301 tagtattttg aatggttttg gatatattgt atgtttggaa aagaagaatg ggagtaattt
      361 taaactaaca aaaaatgcct tgaaatcagt gtttcagagc attttttgtt ctttctgtaa
      421 ataatttgca aactatagta actgttgact tttacttaac catttttcga ttgtaagttc
      481 aaaatggtca actactatta tattttcagg aatcgtatca aaatcaaata ataaattatc
      541 tgaatgagtt tttataacta
//
LOCUS       DAVLTG010000149          510 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLTG010000149 DAVLTG010000000
VERSION     DAVLTG010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.151"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            159..>510
                     /locus_tag="VYN12_002127"
     CDS             159..>510
                     /locus_tag="VYN12_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1416416.1"
                     /translation="MAAGYLNRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSK
                     DSAPVIENLNLTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNINQID
                     KKILSQNLGVVPQDS"
BASE COUNT          185 a           59 c           92 g          174 t
ORIGIN      
        1 tatttcaatt gttcgctcct ataattatat tgatttttgg acttgataat gttttaaatg
       61 gaaaaatttt attgggtgag gttgtcgcat ttcaaaccat ggcatcaatt ttatttagtt
      121 cagaaatctc aatatttaat gcttatacgc agtatatttt ggcagcagga tacttaaata
      181 gagtaaatga tatctggctt gaaaatgaag agaatgttga aaatggtctt aaaaagtgtt
      241 ctttagaagg tagaatagat attaaggacc tatctttctc ttattccaaa gactcagctc
      301 ctgtaataga aaatttaaat ttgactattg agccaggaca gagaattgca ctagtcggtc
      361 aatcggggtc aggaaaaagt acgttatcaa aaatactatc aggattatat aagattgata
      421 caggaaaaat tttatttgat ggtgtaaata ttaatcaaat agataaaaaa atattaagtc
      481 aaaatttagg agtagttcca caggattcat
//
LOCUS       DAVLTG010000150          430 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLTG010000150 DAVLTG010000000
VERSION     DAVLTG010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.152"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..>430)
                     /locus_tag="VYN12_002128"
     CDS             complement(<1..>430)
                     /locus_tag="VYN12_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1416417.1"
                     /translation="CYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAH
                     QLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLK
                     GRTQAVIRNHFLRYDRAVRCRVKIITMDMFSPYYDLARQL"
BASE COUNT          140 a           68 c           90 g          132 t
ORIGIN      
        1 aaaagttgtc tagctaagtc atagtaagga ctaaacatat ccatagtaat gattttgacg
       61 cgacatcgga cggctctatc gtagcgaaga aagtgatttc ggatgacagc ttgtgttctt
      121 cccttaagaa cagtgatgat attgagattg ttaaaatctt gcgcaatgaa gctcatcttt
      181 ccttttgtaa aagcatactc atcccaagac ataatctcag gaagacaaga aaaatcatgt
      241 ttaaagtgaa agtcattgag cttacgaata acagttgaag ttgagatgga aagctgatgg
      301 gcaatatcag tcatagaaat cttttcaatt aacttttgag caatcttttg gttgatgata
      361 cgagggattt ggtgattctt cttgacgata gaagtttcag cgaccatcat ttttgaacag
      421 tgatagcact
//
LOCUS       DAVLTG010000151          404 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVLTG010000151 DAVLTG010000000
VERSION     DAVLTG010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.denovo.153"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(<1..>404)
                     /locus_tag="VYN12_002129"
     CDS             complement(<1..>404)
                     /locus_tag="VYN12_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1416418.1"
                     /translation="KELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVHSLRCLNL
                     ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCF
                     NAQLRPGNRYCSEEADSFITPVLERFNQLLFR"
BASE COUNT          129 a           77 c           94 g          104 t
ORIGIN      
        1 attcgaaaga gaagttgatt aaaccgttct aaaacaggtg tgataaagct gtctgcctct
       61 tcagaacaat aacgattacc aggacgaagc tgggcattga aacaataacc tgtcttcccc
      121 tcgaaagcat aaagaggatg atagccatga gcacgatagt gggcgttata agcaacacct
      181 tcttgcttgc cataagttgt gaaatgggta gaatcgatat ctacaatgag ttggtttagc
      241 tggtgaaact gtaaaaagaa ttcgaccaat tcaaggttga ggcatcgcaa actatggact
      301 gtttcctcgt cagttctgga aagaaaacgg gataaggttg gctgtgaagc aagctgccct
      361 ccttccaaca attttggaaa gtaggcatca gctgacaatt cttt
//
LOCUS       DAVLTG010000152        20977 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.guided.035, whole genome shotgun sequence.
ACCESSION   DAVLTG010000152 DAVLTG010000000
VERSION     DAVLTG010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.guided.035"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            complement(45..2402)
                     /locus_tag="VYN12_002130"
     CDS             complement(45..2402)
                     /locus_tag="VYN12_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1416419.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDSYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEERVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRTFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQAEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            complement(2353..2712)
                     /locus_tag="VYN12_002131"
     CDS             complement(2353..2712)
                     /locus_tag="VYN12_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEV1416420.1"
                     /translation="MNTCVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            complement(2766..3620)
                     /locus_tag="VYN12_002132"
     CDS             complement(2766..3620)
                     /locus_tag="VYN12_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEV1416421.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(3637..3879)
                     /locus_tag="VYN12_002133"
     CDS             complement(3637..3879)
                     /locus_tag="VYN12_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416422.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            complement(3900..5777)
                     /locus_tag="VYN12_002134"
     CDS             complement(3900..5777)
                     /locus_tag="VYN12_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEV1416423.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            complement(5777..6265)
                     /locus_tag="VYN12_002135"
     CDS             complement(5777..6265)
                     /locus_tag="VYN12_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416424.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            complement(6255..6554)
                     /locus_tag="VYN12_002136"
     CDS             complement(6255..6554)
                     /locus_tag="VYN12_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416425.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            7227..7541
                     /locus_tag="VYN12_002137"
     CDS             7227..7541
                     /locus_tag="VYN12_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1416426.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            7557..7943
                     /locus_tag="VYN12_002138"
     CDS             7557..7943
                     /locus_tag="VYN12_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1416427.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            7972..9357
                     /locus_tag="VYN12_002139"
     CDS             7972..9357
                     /locus_tag="VYN12_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1416428.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            9360..9512
                     /locus_tag="VYN12_002140"
     CDS             9360..9512
                     /locus_tag="VYN12_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1416429.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            9535..10740
                     /locus_tag="VYN12_002141"
     CDS             9535..10740
                     /locus_tag="VYN12_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV1416430.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            10783..11004
                     /locus_tag="VYN12_002142"
     CDS             10783..11004
                     /locus_tag="VYN12_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1416431.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            11121..11618
                     /locus_tag="VYN12_002143"
     CDS             11121..11618
                     /locus_tag="VYN12_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1416432.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            11593..12099
                     /locus_tag="VYN12_002144"
     CDS             11593..12099
                     /locus_tag="VYN12_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1416433.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            12083..14530
                     /locus_tag="VYN12_002145"
     CDS             12083..14530
                     /locus_tag="VYN12_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1416434.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            14533..16710
                     /locus_tag="VYN12_002146"
     CDS             14533..16710
                     /locus_tag="VYN12_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1416435.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            16707..17708
                     /locus_tag="VYN12_002147"
     CDS             16707..17708
                     /locus_tag="VYN12_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1416436.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            17705..18640
                     /locus_tag="VYN12_002148"
     CDS             17705..18640
                     /locus_tag="VYN12_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1416437.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            18885..19001
                     /locus_tag="VYN12_002149"
     CDS             18885..19001
                     /locus_tag="VYN12_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1416438.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            19017..20936
                     /gene="tet(M)"
                     /locus_tag="VYN12_002150"
     CDS             19017..20936
                     /gene="tet(M)"
                     /locus_tag="VYN12_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1416439.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         6620 a         3998 c         4128 g         6231 t
ORIGIN      
        1 tcgggcacgt atgatttctc ttttatcctt catttacctt ccccttaatt agaagccatt
       61 ttatcaggat ccgtactcat gatatcaaac aattgagtac cttgaggaat cttattttta
      121 aagggaacga caactgaacc agcttttatt agtccagccc ctttttctgg attgactagg
      181 tatttttcga gttcttttga caagcctaag agttgaacca attcttctct atcatttttt
      241 gcttgcttga ggagaatcat aaattcacta tttgcaataa tccgtctacc atttggatct
      301 aacaataagg tttcgacgtt ttgggttatc ccagtcggac tggctccata ttttctgaca
      361 cgactccaca atttaaagaa gaaatcactg gcatatttat ctaataagag aagctgcatc
      421 tcatcgaaat aaatccaggt cttcttccct aatttttgat tccgaacgac acgattccat
      481 atctgatcaa aaacaaccat aagggcaatt tgtttcagct catctcctaa ctttttaaca
      541 ttatagatta agaaattgga ccctgtttga atattggtct tatgagaaaa aatatcaaga
      601 gaaccttcaa catacagttc catatcaagt gccaaattct gcgcttcttc ttctgcttgt
      661 tggctcaaga caaagaccca ttcttccaaa gaaggctctt taaatgactg ataagtgagt
      721 ctcgtaactc ggtcgataat cgatttttct ctcccatcca tttttctatc caataactta
      781 ccgataaagg ataaaagaaa ttctgatttt acctttacag gatcctcatc catattttcc
      841 tcagacaagt caaggacatt gagataggtt tgggaatcag gcgcaatatc aatcatttct
      901 cccccaaaag ttcgtccaat gacactgtac tctgcttctg gatccacgat gataatttca
      961 gtattttcac cagattcctt gattttggtc gtgataattt catgcttggt tgccatccct
     1021 ttcccagctc cagatgttcc taaaatcaga ccagacggtg tatttaatag gctgcgatca
     1081 atggtaataa tattacttga tatttgattg ataccgtaat atttcccact acggtcttgt
     1141 aagtctactg aagtccaagg tgagttcact gctacattag atgttaataa actccgtgat
     1201 actccctcta aaaaatcaca accaaatggt agcaaactat taaaggctgc ttcttgcata
     1261 tatggtagtt tatcaatcat taggtcattt gagccagcca cttgttgaat agtgtctagt
     1321 gcttgtttga gttcttcttc atcctgacca aaaacaccaa tcaagaagac tgtttgaaat
     1381 agtttatctc ctgtctcggt catggttttt aagagttcct cagcttcatc gatattgctt
     1441 tctaatacat gacctacttt ttccaaatag atacctgtac gagcaagttt ttgttgttcc
     1501 ccgatctttt gggattccat caaggtcttc tttgttcgta gtttcttcat ggcatctgcc
     1561 ttggtcgaac tttgagcatg gaggcttaca atcaattcca aatctccttg catgaggtct
     1621 ctgataaact gatctcctaa ttccataccg tagtctctca catagacaat ctgtaataaa
     1681 cggtcattga tttgtaggta attcttgttt ttaaaatcca agagattagg tgctatgaag
     1741 tgacgagttg tctgacccga tctcgttaaa tcacggtaag aaaaaggaag atggtgttct
     1801 cctctaagca tatcggccaa caagttcacc cgttcttctc cagccaagga ttcaaatcgt
     1861 gcatcaattt ctgagaaacc actcttgaaa tattcgccta tttgagacaa ggaacgatag
     1921 gcttgtttgg gattagaatc ctttctacca aaactaatca gtttcacagc tgaaaaatta
     1981 ttttcaccac tgtctaaatt ctgattcatc atccgattca attctttacg atagctatca
     2041 tacccatctt ctttttcctc atacagaaca ctctgtctaa acttttctaa attcaatctt
     2101 ttattaaaga tagtcaattg gaagttggtt tggtcatcta gtgagttaat caaatcagaa
     2161 tacttctcaa tgattgcgcc cttatcttct aaaccaacgg tctggtaatt gacatcacca
     2221 agtaaatagc tttgtgagaa ataatcttct tttacctgca tcagaccatt ttgatacagg
     2281 gcttgatagg aaagagtatt agccgttgag ggtaacactt cctctttttt ccctttaact
     2341 tcttcctttt tattagtcat tgaagttttt tgtttcttta atgtatttga ttttcttttc
     2401 atgttcaggt cctttctttc ctgtaattgt gcgtagggga accgttaatt caaaatgaag
     2461 acggtatttc aaataatgtt caaaatataa atcattgggt ttatagactc caaaaagcat
     2521 tagggggatg gtaaaagcaa acacaaaacc gtaaacaaac caatctccaa attgccagaa
     2581 aaagagattc aagcccaaaa caataattgt gacaataaag gctggtaaaa caaagatgat
     2641 ttgtcttgtg gtgaaaccta accaagccct gtgttggtat tttgagatgt ctttaaagac
     2701 acatgtattc atgactttcc tttctaaaaa ggctaagaag caatcacttc ctagccttta
     2761 tctaattaca tacctaagat tgagcgagcc gtacgttgag aaccaacgag ggcaataatc
     2821 agtaagatag cttgtactaa actaccaaac ataatcgcaa gtgattgcaa gactcctgca
     2881 ccatttgaaa cagctatttt cccagcagat tcaaacaaag gaacaagaga aacaatcaga
     2941 aaaatgagaa ccccttgtac cgcatagacc ataatatttt ttaaatagcc aataccaata
     3001 gacttccatt catcacttaa aaatgttgga atcgtaagag gggcaaatgg gatcataagg
     3061 tagagttgaa taaatcgaat agataccaaa agattaacca tggctgcact tactatccga
     3121 acaagccaga taaggagagc gaaaaagccc acaatcatcc ggccaataaa tcctgaacct
     3181 tttaatccag agagtgtatc atacttcgcc ccaccgtgag ccacaatcga ggccacttgt
     3241 tcgatggcgt gactcgcaat cccgatgata gcttctacta taacggtagt attggtaatg
     3301 accactgcga ccataatata actaatcaac atcggcgcta atgcttcaaa ggtcatcgct
     3361 ccaccagagt tagcaatctt ctttgccatc ttcgaaaatt ctaagatgag aacaactgat
     3421 aaaatcgcaa ctccaagagg ctgcatgaca cttttagtaa tactagacat ataagtccaa
     3481 actgttggat tgtagctaga tagggattta atcagatcta ccgtagattg taaatccaca
     3541 ttaaatcctt caaataaatt ttcagctgat attttttcag atgcaaggta aacaaagggt
     3601 gagactaaac taagattcat gtcattgttt atcctcctaa attgaaatct gggttacaaa
     3661 ggctccagca gcccctacca taacaccacc gacaatttca agaatggcat tccgaacacc
     3721 tggtccacca tctttaatgt tggttgcaag gttgacaatc cccacaacaa cgagaaaggc
     3781 accaactgca atcaatccct tctgtaacaa agacatagct tgtgcaaaca tagcacttgc
     3841 gtctactcca taaacaaaac ctttaaaatg cgtaatcatc tatttcctct tttctatttt
     3901 tattttaaac tagattcaaa agttaaatca cgaattctaa ggtcgtcaag ataattttct
     3961 tgtctttgat tcaaaggatt gatttgatag ttccaccacc gttcatcgct ttcttgatta
     4021 gctaggtact tccagtttgg atgcttagtg gaattgtatt ttttgctttt aaagacaggc
     4081 atattggcaa ttcgaaccaa gcattcatgc cgtttcatat ttccgacctc atcgggtgtc
     4141 attaagtcac gagcaatctt ttgatgagaa agggatcctg aacctgtttg gccaaaggaa
     4201 cgactagtat ttcgaacatc aatggtttgt ttaccgagta agccactcat aaatttaaag
     4261 gtatcttcat cattaccacc taagtagact aagctatcac agttccccaa aatggttttc
     4321 caagcttctt tttctttata gagcccttga agttgggcaa tattttgaag aataggaacg
     4381 agactcatat ttcgagaacg gactgttgag gtttgttcag caaaatctgg aatttctccg
     4441 atatttgcga actcatctaa gtaaactctc acatgaagag gcaattgacc cttaaaatca
     4501 atatctgctt gtcttgttag ggtttgaaat acggttgaaa aaaagagggc tgaaagaaag
     4561 cgaaaggtac tatcgttatc tgggataact aagtaaacca ttgatttttc cttgccccat
     4621 gtcttcatat caagggtatc tcttttggtc aagtccatga cactttgaat attgaagagg
     4681 gcaaatttag cagtggttac agctataaca gaatccagag tcttatcctt ataattttga
     4741 aaatctgccc aatttcgcat ggtaaaattt tcagtcccat actttttagc ataattttca
     4801 aatagaattt ctaagacact tttttcctgg ttttcaccct tggataagtg tttaatgagt
     4861 tttgagattt cagcaaaact tggataacga cctcgttttt ttcgctcttc cacttctttt
     4921 ttttgacgtt tcaacaagtt ttgatattcc ttttgactta aacgactttc ttctatgagc
     4981 tgttctcttg ttttaggtgg attatagaaa tcgactaagt aagaggctaa agctcgaacc
     5041 aaagtcatag aagcttcatc ccaaaatgga tcacttcggg agccagagcc tttggtgtta
     5101 ttaaaataaa cagtcagcat gcgattcaaa tcgttttctg tttctatata gcgaaaagga
     5161 ttaaagccat ctgagttctt catattgact aaatctaaca cctttacttg gtagccatgt
     5221 tctaaaaaga gtttgcctgt tttctcggcc aagtgatctt taggatccac tacaatatta
     5281 gaactattca tctgaatcag attgggtttc acaaagcgaa atgtcttccc acttcctgaa
     5341 cctccaatca ccgcaatatt cttatttcta tcatattggg gtggtttttt atctaataat
     5401 gtcaaacgaa catcttgtgc taagatcgta tcatgagaaa attccttacc gtaaaagagc
     5461 ttcttttctt ttagagttcc aaaacgggcg ctcccgtatt ctaccccttc tcggtattgt
     5521 tttttaccag tctctagata gagataaacc agtaacatca tcacaaaacc tagtagaaaa
     5581 aaagcacttg attttccagt aaaagaaaca ttccatggcg actgaagaac ttcatcttga
     5641 ccttccatca gaagatgagt ccatttatct aaggtatttc cagtatagga atcatacaaa
     5701 agcgtcaaac gatgaaaaag atagcctagt aagataccta acagtgagaa tagtaggaat
     5761 ttttttccac tgtacatcat ctcaccatct ctttctgttt gacggctcct tcttgtctaa
     5821 aggtaatttg ggatttagct tcatcaatag catcatctaa tgacttatcc atggtaaaat
     5881 cagctaattt ctccggatca ttaaccattt tttctaaaag atggtctaaa tgattgtcta
     5941 aaatcgaacg gtctttcgcg tagaaatgta gagaatcccc ttgccaagcg atggctaaag
     6001 gaatctcttc tttttctaaa aaagctttaa atttctctat atcaattggt ttgtctaaaa
     6061 aatctttttt cagattaatc gtatcaatcg catagggaga ttgtagcaat tcttctaatt
     6121 tctgcactcc tatcttatag gcggaatcct gtgctaaagc ctgacgtcta gaccattcta
     6181 gaatctttaa aagacttttt acagtaaata aaagactacg ctctgcatat tgaactgcca
     6241 ttcgttcctg ttgttcagag gacatctgat gcctccttct tcacaaatag cagctttcct
     6301 tctttataac gataagctat caatttctga cgttgcttaa tcgacttgac aaccttcagt
     6361 agatctctcg aataaggttc tcgaagagtg acttctactg ccttcccatc aacgatacca
     6421 acacgtttaa attcaatgta gtcttttttg agatgtccta agcccatacc aaaaggaaag
     6481 tgatgaatca attggatggt acaaccacct ttatttccca tttgtttcaa atcatacaag
     6541 tttactacct tcatgattaa ctcctttatc tagtttgtcg catcgtttaa gtctggtaac
     6601 gataaactcc gtgtctgtta gaaaattctc acacacgtct tgtgccagtt gcccttcaca
     6661 gggaaatact ctcagtccct acttacacag gcacgctaat caagacggag tggattcaat
     6721 tttcaaagaa caggtagctt tattatagag aagagtagtt gaaattttta tcacattttt
     6781 tatttttctg tagagctaaa ttcatactaa acaaagattt tgaaataaaa gactaacatt
     6841 gttacataac gttagcattt catttcccta aaataagcta attttgtcta aaaaatagca
     6901 taaaaatcta gttatccgca taaaaactgg acttatcaca ctttatcaag gtcaaaacca
     6961 ctcaatttac tactaattta ctacttatga atgagctttg atacgacgat ttatccttga
     7021 aaagtgaaga tataaagata cttccaataa aatttgaata tttaataggt agacacttca
     7081 aaaaatgagg tgtctatttt tttacccgat tttgaaagga agtgaactta tgaaaacaaa
     7141 aaatcaagaa tcaaaaggtc gttccccact ctttaagacc atcaaacatt cattcagcca
     7201 ataaaaaaga aaggataggt aaaaatatgg aacttaaatt tgtgattccc aacatggaaa
     7261 aaacattcgg caatttagaa tttgctggcg aggataaagt cgttcagcga agaatcaacg
     7321 gacggctaac tgtcttatca agaagctata atctctattc tgatgttcaa agagcagatg
     7381 atattgtggt ggtgcttcct gctgaagctg gcgaaaaaca tttcggcttt gaggaacgtg
     7441 tgaagttagt caatccacgt attaccgcag agggctacaa aatcggcact cgtggtttta
     7501 caaattacct tttacatgct gacgacatga taaaagaata aagaaagaga ggaaaaatga
     7561 tgagattagc aaatggcatt gtattagata aagacacgac ttttggagaa ttgaaattct
     7621 ctgctctacg tcgtgaagtg agaatccaaa atgaagacgg gtcggtttca gatgaaatca
     7681 aggaacgtac ctatgactta aaatccaaag gacaaggacg catgattcaa gtaagtattc
     7741 ctgccagcgt gcctttgaaa gagtttgatt ataacgcacg ggtggaactt atcaatccca
     7801 ttgcggacac cgttgctact gccacctatc aaggagcaga tgttgactgg tatatcaagg
     7861 cagacgatat tgtgctgaca aaggattcta gttcattcaa agctcaacca caagcaaaga
     7921 aagaaccgac acaagacaaa tagtcgctag gtagaaagga gactttttcg catgaaacag
     7981 cgtggtaaaa ggattcgccc atctggtaaa gatttagtct ttcattttac gatagcgtca
     8041 ctcctgcctg ttttcctgct ggttgtcgga ctgtttcatg tgaagacaat ccagcagatc
     8101 aactggcagg attttaacct atcacaagca gataagattg acattcccta tttaattatc
     8161 agtttcagtg tcgcaattct tatctgcttg ctggtagcgt ttgtattcaa acgggttcgc
     8221 tatgatacgg ttaaacaact ttaccaccgt caaaaactgg caaagatgat acttgaaaac
     8281 aagtggtatg aatctgaaca ggtcaaaaca gagggtttct ttaaagatag tgctggtcgt
     8341 acaaaggaaa agataaccta cttccctaaa atgtattatc gacttaaaaa tggcttgata
     8401 cagatacggg tggaaatcac gctgggaaaa tatcaagacc aactcttaca cttggaaaag
     8461 aaattagaga gtggcttgta ctgtgagctg acggataaag agttaaagga ttcctatgtg
     8521 gaatatactt tgctctatga caccatagcc agtcgtattt ctattgatga agtagaagct
     8581 aaagatggta aacttcgctt aatgaaaaac gtatggtggg aatatgataa gctccctcat
     8641 atgttgattg ctggtggtac aggtggcggt aaaacttact ttatactgac actgattgaa
     8701 gccttgcttc atacagattc aaaactgtat attcttgacc cgaaaaatgc tgaccttgcg
     8761 gacttaggtt ctgtgatggc aaatgtctac tatagaaaag aagacttgct ttcttgcatt
     8821 gaaacattct atgaagaaat gatgaaacgt agtgaggaaa tgaagcagat gaagaactat
     8881 aagactggca aaaattatgc ttacttaggt ctcccggcac acttcttaat ctttgatgaa
     8941 tacgtcgctt tcatggaaat gctgggaaca aaagaaaaca ccgcagttat gaataagctg
     9001 aaacagattg tcatgttagg tcgtcaagct ggcttctttc taatactggc ttgtcaacgt
     9061 ccagacgcaa aatatttagg cgacggaatc cgtgatcagt ttaatttcag agtggcttta
     9121 ggtcgtatgt ctgaaatggg ctatggcatg atgtttggca gtgacgtaca aaaggatttc
     9181 ttcttaaagc gaatcaaagg tcgtggctat gttgatgtag gaacaagtgt catatcagag
     9241 ttttatactc cccttgtacc aaaaggatat gatttcttgg aggaaattaa aaagttatcc
     9301 aacagcagac agtccacgca ggcgacgtgc gaagcggaag tcgcaggtgt ggactgatct
     9361 tgctggctgg tgtggcaata gccacgccag cacttaaccc cccgtatcta acaggggggt
     9421 acaaatcgac aggaaacagt caaaaaaaca ttagaaaatc ctttggttac aagggattta
     9481 caaaatttca gcgtatgtca aatgggcttt aaaagttgac atacgccttt ttgattggag
     9541 ggatttttac tgaatgaaca aacttggtta cagcatttaa aagaaaaacg cttggcttat
     9601 ggactatctc aaaaccgttt agctgttgcg actggtatta caaggcagta tctaagcgat
     9661 attgaaacag gaaaagtcaa gccatcagag gatttacagc agtccctttg ggaagctctg
     9721 gaacgcttca atcccgacgc tccccttgaa atgctgtttg attatgtaag gattcgcttt
     9781 ccgacaacag acgtacagca ggtggtcgaa aacatcttac aactgaaact gtcctatttt
     9841 cttcatgagg actatggttt ctattcttat tcagagcatt atgctttagg cgacatattc
     9901 gtcctttgct cccatgaact ggacaaagga gttctggtgg aattgaaagg tcgtgggtgc
     9961 agacaatttg aaagctatct tctggcacaa caaagaagct ggtatgagtt ctttatggac
    10021 gttttggtgg ctggcggtgt gatgaaacgc cttgaccttg ccattaacga taagacaggg
    10081 attttgaata tccctgtact cactgaaaag tgccaacagg aagaatgtat ctccgtcttc
    10141 cgcagtttta aaagctatcg cagtggcgaa ctggtacgca aagaggaaaa ggaatgtatg
    10201 ggaaacaccc tctatatcgg ttcattacaa agtgaagttt atttctgtat ctatgaaaag
    10261 gactacgagc agtacaagaa aaatgatatt cccattgaag acgcagaagt aaaaaaccgt
    10321 tttgagattc gattgaaaaa tgagcgtgcc tattatgcag tccgtgattt actcgtctat
    10381 gacaatccag agcataccgc ctttaaaatt atcaatcggt atatccgttt tgtagataaa
    10441 gacgattcca aacctcgttc tgattggaaa ctgaatgaag aatgggcttg gtttattggg
    10501 aacaatcgtg aacgattaaa actaaccaca aaaccagagc cttactcctt ccaaaggacg
    10561 ctgaactggc tatctcatca agttgccccg accttaaagg ttgcgattaa acttgatgaa
    10621 atcaaccaga cgcaggttgt aaaagacatt ctcgaccatg cgaaactgac agaccgacac
    10681 aagcagattt tgaagcaaca gtcagtaaaa gaacaggacg tgataacaac aaaaaaataa
    10741 ctcaaataca aattcattga atatagagag gagaacattt ttatgaattt tggacaaaac
    10801 ctttataact ggtttctatc aaacgctcaa tcactggtgc ttttagcaat cgttgtgatt
    10861 ggcttgtatc ttggcttcaa gcgtgagttt agcaaactga ttggcttttt aattattgcg
    10921 attattgcgg ttggcttagt cttcaacgct gctggagtaa aagacatttt actagagcta
    10981 ttcaatcgca ttattggtgc ttaaataaaa ccgttctttt gtggaatata agtggttttc
    11041 ttatgttccg caaaggaatg gtacaccaaa cgaagtgcgg tagggatttt tgaatctcta
    11101 caaagaaagg acgtgaatat atggacgata tgcaagtcta tattgcgaat ttaggcaaat
    11161 acaatgaggg cgaattggtc ggtgcgtggt ttacctttcc cattgacttt gaggaagtca
    11221 aagagaaaat cggcttgaat gatgaatatg aggaatacgc cattcatgac tacgagttac
    11281 cctttacggt tgacgaatac acttccattg gcgaactcaa tcgactatgg gaaatggtat
    11341 cggaattacc cgaagaatta caatcggagc tatctgctct gctcactcat ttttcaagca
    11401 ttgaagaact aagcgaacat caagaggata ttatcattca ttccgattgt gatgatatgt
    11461 atgacgtggc acgctactac attgaagaaa cgggtgcttt aggcgaagta ccagctagtc
    11521 ttcaaaacta tattgattat caagcctatg gtcgggattt agacctttca ggaacgttta
    11581 tctcaaccaa tcatgggatt tttgaaatcg tctattaaat ctgtcggtac attactactg
    11641 gcagattttc tattttacgg ggtggctcaa tcagctaccc ctatttttta tgaaaggatt
    11701 gattacatga agaaaatacg aagctatacc agtatctggt ctgtggaaaa ggtactgtat
    11761 tctatcaatg attttagact tccgtttccc ataaccttta cgcaaatgac atggtttgtc
    11821 gtgtcactct ttgcagtgat gatacttggc aacttgcccc ctctttccat gatagaggga
    11881 gcatttctca aatactttgg gattcctgtg gctttcacat ggtttatgtc tacaaaaact
    11941 tttgatggta aaaagcctta tggatttttg aagtctgtca ttgcttatgc actgcgacca
    12001 aagctgacct atgcaggaaa aaaagtaacg cttggcagaa accagccaca agaagccatt
    12061 acagcagtta ggagtgaatt ttatggcata tccaattaaa tacattgaaa acaatctcgt
    12121 ctggaataaa gacggggaat gttatgctta ctatgagctt gttccttaca attactcatt
    12181 tctaagtcca gaacagaaaa tacaagtgca tgattctttc agacagctta tcgcacaaaa
    12241 tcgtgatggc aaaattcatg ctttacaaat cagtacagaa tccagcatac gttctgcaca
    12301 agagcgttcc aaaaatgaag tcactggcaa gctcaaagcg gttgcctatg acaaaatcga
    12361 ccaacagaca gacgctttaa tatccatgat tggcgaaaat caagtgaact accgtttctt
    12421 tatcggcttt aagttgcttc tcaacgatca ggagttttct atgaaaagtc ttaccgttga
    12481 agcaaaaaat gctttgtctg attttgtcta tgatgtgaac cataagctga tgggcgattt
    12541 tgttagtatg agtaatgatg aaatcctgcg ttttcagaag atggaaaagc tcttagaaaa
    12601 taaaatctct cgtcgtttca aaatccgcag gttagataag gacgacttcg gctatctgat
    12661 tgaacacctt tacggacaga caggcactgc ctatgaagag tatgagtacc atctatcaaa
    12721 gaaaaagctg gataatgaaa cgctgattaa atactatgac ttgattaagc ctactcgctg
    12781 tttggtggaa gaaaaacagc gatatttgaa aatccagcag gaagatgaaa ccgtctatgt
    12841 agcttacttt accattaaca gcattgtcgg agaactggac ttcccgtcct ctgaaatctt
    12901 ctactaccag caacagcaat ttacattccc gattgatacg tcaatgaatg tggaaattgt
    12961 agcgaatcgt aaagccctat ctactgtccg caataaaaag aaagaactga aagacttgga
    13021 taaccacgct tggcaaagtg ataatgaaac cagctccaat gtggcggaag ctctggaaag
    13081 tgtgaatgag ctggaaacca atttagacca aagcaaggaa tctatgtaca agctgtctta
    13141 tgtggtaagg gtatcagcaa atgatcttga cgaactcaaa cgtcgttgta atgaagtgaa
    13201 agatttttat gacgatttaa gcgtaaaact ggtacgacca tttggggata tgctcggctt
    13261 acatgaagaa tttttacctg ccagcaagcg ttatatgaat gattatattc aatacgtgac
    13321 ctctgatttc ctcgctggtt taggttttgg tgctactcaa atgctggggg aaaatgaggg
    13381 gatttatgtt ggctacagct tagatactgg acgcaatgtc tatctgaaac ctgctcttgc
    13441 cagtcaaggg gttaagggtt cagtaaccaa tgcgttagcg tcggcttttg ttggttcgct
    13501 gggtggtggt aaatcctttg cgaataacct tatcgtctat tatgcggtgc tttatggggc
    13561 acaagcagtg attgtagacc caaaagcaga acgtggcaga tggaaagaaa ccttgccaga
    13621 gatttcccat gaaatcaata tcgtcactct gacttctgat gagaaaaaca aaggcttact
    13681 tgacccttat gtgattatga aaaatcccaa agattctgaa tcactggcta ttgatattct
    13741 gacattcctt acggggattt cctctcgtga tggggaacgc ttcccaatcc ttagaaaagc
    13801 cattcgtgca gtaaccaata gtgaagtacg agggttgatg aaagtgattg aggaattacg
    13861 ggttgagaat acgccactaa gtaccagtat agccgaccat atcgaaagtt ttacagacta
    13921 tgactttgca catttattat tcagtaatgg ttatgtggag cagtctatca gcttagaaaa
    13981 acaactgaac attatacagg ttgcggactt ggtacttccc gacaaggaaa cttcctttga
    14041 ggaatatacc actatggagc ttttatccgt tgctatgctg attgtcatta gtacctttgc
    14101 tttagacttt atccatacag accgaagcat tttcaagatt gtagatttag acgaagcatg
    14161 gagcttttta caggtagcac aaggaaaaac actatctatg aagctggttc gggctggtcg
    14221 tgctatgaac gctggggtat atttcgtgac ccaaaataca gacgacctct tagatgaaaa
    14281 actgaaaaat aacctcggct taaaatttgc atttcgttcc actgacctta acgagattaa
    14341 aaagacctta gccttttttg gtgtagaccc agaggacgaa aacaatcaga agcgattgcg
    14401 tgatttggaa aacgggcaat gccttatcag tgatttatat ggtcgtgtcg gtgtgataca
    14461 gttccaccct gtatttgaag aactgctcca tgcctttgat accagaccac ctgtgcgaaa
    14521 agaggtgtaa atgtgaaacc atcaatagta aacagaataa aatcaaactg gacgctgaaa
    14581 cgtctaggta aagtggcaat gacagtggct ttcacacttg tgattgccat ttttctttta
    14641 gccatgctgg gaacggtggt tcaagctgcg ggcttggtag atgatacggt caatgtggca
    14701 aatgaataca gccgataccc acttgaaaac tatcaactgg atttttatgt ggataatagc
    14761 tggggctggc ttccgtggaa ctggtcggac gggattggaa aacaggtcat gtatggacta
    14821 tatgccatta ccaattttat ttggacaatc agtttgtatg tttccaatgc gacaggttac
    14881 ttagtacagg aagcctattc cttagacttc atttccgcta cagcagattc cattggtaag
    14941 aatatgcaga ccttagctgg tgtgagtgca aacggatttt caacagaggg tttctatgtt
    15001 ggattcctct tactcttgat tttggttctt ggggtttatg ttgcctatac gggactgata
    15061 aagagagaaa ccacaaaggc aattcatgcc attatgaatt ttgtgctggt gtttatccta
    15121 tcggcttcct ttattgccta cgctcccgac tacattaaaa aaatcaatga cttttcatca
    15181 gacatcagta atgccagttt atcacttggc acgaagattg tcatgcccca ttccgatagt
    15241 caaggcaagg acagcgtgga cttaatcaga gatagcctgt tttccataca ggttcagcaa
    15301 ccgtggctac tgcttcaata caacagttca gacattgaaa gtatcggtat tgaccgtgtg
    15361 gaaagcctgc tctccaccag cccagattcc aacaatggcg aagacagaga aaaaattgtt
    15421 gcggaagaaa ttgaagacag aagcaatacc aatctaacca ttacaaagac cattaaccgt
    15481 ttaggtacag tcttcttcct atttgtcttc aatattggga tttccatatt tgtattccta
    15541 ttaacaggaa tcatgatttt ctcgcaggta ctttttatca tctatgctat gtttctgcct
    15601 gtgagcttta ttttaagcat gattccatca tttgatggta tgtcaaaacg agccataaca
    15661 aagctcttta ataccatttt gacacgagct ggaatcacat tgattattac gacagcattt
    15721 agtatttcaa ccatgctcta taccttatcg gctggttatc cgttcttttt gattgctttt
    15781 ctacagattg tgacctttgc aggaatctac ttcaagctgg gcgatttaat gagtatgttt
    15841 tctctacaga gtaacgattc tcaaagtgtg ggaagtcgtg tgatgagaaa acctcgtatg
    15901 cttatgcacg ctcacatgca ccgtctacag cggaaacttg gacgttccat gactactcta
    15961 ggggctgggt ctgccattgt tacaggtaaa aaaggacagt cgggttcggg gagttctgca
    16021 aggacacaag cagatcactc ccgaccagac ggaaaggaaa aatcaacact tggaaaacgt
    16081 atcggtcaaa ccatcggtac agtagctgat accaaagaca gaatggtaga cactgctagt
    16141 ggtttgaaag aacaggttaa agatttgccg accaatgcaa gatatgcagt atatcaagga
    16201 aaatccaaag taaaagagaa tgtccgtgat ttaaccagta gtatttctca aaccaaagcg
    16261 gacagagcca gtggacgcaa ggaacagcag gaacaaaggc gaaaaaccat tgcgaagcgt
    16321 cgctctgaaa tggaacaggt caaacagaaa aaacagcctg cttcttctgt tcatgaaaga
    16381 ccgactacaa gacaagaaca atatcatgat gaacagacct caaaacagtc taatattcag
    16441 acttcatata aggaatctca acaagccaaa caagagcgtc cagcagttaa gtccgatttt
    16501 tcaagtccaa aagtggaacg ccaaggcaat accgttcaag aaaaaaccgt tcaaaagcca
    16561 gcaacttcaa ccactacagc agatagaact tcacaacgtc caatcacaaa agaacgtccg
    16621 tctactgttc aaagagtacc actacaaaat acaagaagta gaccaccaat caaaaccgcc
    16681 accattaaga aagtcggtaa gaaaccatga agttgaaaac tttagtgatt ggtggttctg
    16741 gattattctt gatggtcttc tcactgcttc tgtttgttgc cattttattt tcagatgaac
    16801 aggacagcgg aatttccaat attcattatg gaggtgtgaa tgtttccgca gaagtgctgg
    16861 ctcataagcc tatggtagaa aaatatgcca aagaatatgg cgttgaagaa tatgtcaaca
    16921 tacttcttgc gattatacag gtggaatcgg gcggtactgc ggaagatgtt atgcagtcct
    16981 cggaatccct cggtcttcca cctaattcat tgagtacaga agaatccatt aagcaaggtg
    17041 tgaagtattt cagtgaatta ttagccagta gcgaaaggct cagtgtagat ttagaatcgg
    17101 ttatccagtc ctacaattat ggtggtggtt tcttagggta tgtggctaat cgtggaaata
    17161 aatatacctt tgaactggct caaagtttct caaaagagta ttcaggtggc gaaaaagtgt
    17221 cttaccccaa tcccatagcc atacctatca atgggggctg gcgatacaac tatggcaata
    17281 tgttttatgt gcaactggta acgcagtatc ttgtcacaac agagtttgat gatgatacgg
    17341 tacaagccat catggacgaa gcactgaaat atgagggctg gcgatacgtt tacggtggag
    17401 cttccccgac tacttctttt gattgtagcg gactgacaca atggacgtat ggaaaagctg
    17461 gaattaactt accacgaacc gcacaacagc aatatgatgt gacccagcat atcccactat
    17521 cggaagcaca agctggcgat ttggttttct ttcattctac ctataacgct ggctcttata
    17581 ttactcatgt tgggatatac cttggcaata accgtatgtt tcatgcaggc gacccaatcg
    17641 gttatgccga cttaacaagc ccctactggc aacagcattt agtgggagca ggacgaatca
    17701 aacaatgaga aaggaagatt taatgatgaa atttagaaaa aatcagaata aagaaaaaca
    17761 gataccaaag gaaaagaaac ctcgtgtcta ctataaggtc aatcctcata aaaaggttgt
    17821 gattgccttg tgggtacttt tagggcttag tttcagcttt gcgatattca agcactttac
    17881 agctatagat actcatacta ttcacgaaac aactatcata gaaaaggaat acgttgatac
    17941 tcatcatgta gaaaattttg tagagaactt tgcgaaagtc tactattcat gggagcaatc
    18001 cgataagtcc attgataatc gaatggaaag tctaaaaggc tatctgacag atgaacttca
    18061 agctctcaat gttgatacag tacgcaaaga tattcctgta tcgtcttctg taagaggatt
    18121 tcagatatgg acggtagagc caactggcga caatgagttt aatgtaacct acagtgtaga
    18181 ccagctcatt acagagggag aaaatacaaa gaccgtccac tctgcttata tagtgagtgt
    18241 ctatgtagat ggttctggaa atatggtact ggttaagaat ccgaccatta ccaacatacc
    18301 taagaaatca agttataaac caaaagccat tgaaagtgag gggacggttg attccattac
    18361 aaccaatgaa atcaatgagt ttttaacgac gttcttcaag ctctatccta cagcgacagc
    18421 cagtgaactt tcctactatg tgaatgacgg gatattaaaa ccaatcggaa aagagtacat
    18481 ctttcaagaa ctggtaaatc ctattcacaa tcgtaaggat aatcaagtca cggtatcgct
    18541 gacagtggag tatatcgacc agcagaccaa agcaacgcag gtatctcaat ttgatttggt
    18601 acttgaaaag aacgggagta attggaagat tatagaataa caaatattgg tacattatta
    18661 cagctatttt gtaatcacgt actctctttg ataaaaaatt ggagattcct ttacaaatat
    18721 gctcttatgt gctattattt aagtatctat ttaaaaggag ttaataaata tgcggcaagg
    18781 tattcttaaa taaactgtca atttgatagt gggaacaaat aattggatgt ccttttttag
    18841 gagggcttag ttttttgtac ccagtttaag aataccttta tcatgtgatt ctaaagtatc
    18901 cggagaatat ctgtatgctt tgtatgccta tggttatgca taaaaatccc agtgataaga
    18961 gtatttatca ctgggatttt tatgcccttt tgggcttttg aatggaggaa aatcacatga
    19021 aaattattaa tattggagtt ttagctcatg ttgatgcggg aaaaactacc ttaacagaaa
    19081 gcttattata taacagtgga gcgattacag aattaggaag cgtggacaga ggtacaacga
    19141 ggacggataa tacgctttta gaacgtcaga gaggaattac aattcagaca ggaataacct
    19201 cttttcagtg ggaaaatacg aaggtgaaca tcatagacac gccaggacat atggattttt
    19261 tagcagaagt atatcgttca ttatcagtat tagatggggc aattctactg atttctgcaa
    19321 aagatggcgt acaagcacaa actcgtatat tgtttcatgc acttaggaaa ataggtattc
    19381 ccacaatctt ttttatcaat aagattgacc aaaatggaat tgatttatca acggtttatc
    19441 aggatattaa agagaaactt tctgcggaaa ttgtaatcaa acagaaggta gaactgcatc
    19501 ctaatatgcg tgtaatgaac tttaccgaat ctgaacaatg ggatatggta atagaaggaa
    19561 atgattacct tttggagaaa tatacgtctg ggaaattatt ggaagcatta gaactcgaac
    19621 aagaggaaag cataagattt cataattgtt ccctgttccc tgtttatcac ggaagtgcaa
    19681 aaaacaatat agggattgat aaccttatag aagtgattac gaataaattt tattcatcaa
    19741 cacatcgagg tcagtctgaa ctttgcggaa aagttttcaa aattgagtat tcggaaaaaa
    19801 gacagcgtct tgcatatata cgtctttata gtggcgtact gcatttgcga gattcggtta
    19861 gaatatcgga aaaggaaaaa ataaaaatta cagaaatgta tacttcaata aatggtgaat
    19921 tatgtaaaat cgataaggct tattccgggg aaattgttat tttgcagaat gagtttttga
    19981 agttaaatag tgttcttgga gatacaaagc tattgccaca gagagagaga attgaaaatc
    20041 ccctccctct gctgcaaacg actgttgaac cgagcaaacc tcaacaaagg gaaatgttac
    20101 ttgatgcact tttagaaatc tccgacagtg acccgcttct gcgatattat gtggattctg
    20161 cgacacatga aatcatactt tctttcttag ggaaagtaca aatggaagtg acttgtgctc
    20221 tgctgcaaga aaagtatcat gtggagatag aaataaaaga gcctacagtc atttatatgg
    20281 aaagaccgtt aaaaaaagca gagtatacca ttcacatcga agttccaccg aatcctttct
    20341 gggcttccat tggtctatct gtagcacagc ttccattagg gagcggagta cagtatgaga
    20401 gctcggtttc tcttggatac ttaaatcaat cgtttcaaaa tgcagttatg gaggggatac
    20461 gctatggctg tgaacaagga ttgtatggtt ggaatgtgac ggactgtaaa atctgtttta
    20521 agtatggctt atactatagc cctgttagta ccccagcaga ttttcggatg cttgctccta
    20581 ttgtattgga acaagtctta aaaaaagctg gaacagaatt gttagagcca tatcttagtt
    20641 ttaaaattta tgcgccacag gaatatcttt cacgagcata caacgatgct cctaaatatt
    20701 gtgcgaacat cgtagacact caattgaaaa ataatgaggt cattcttagt ggagaaatcc
    20761 ctgctcggtg tattcaagaa tatcgtagtg atttaacttt ctttacaaat ggacgtagtg
    20821 tttgtttaac agagttaaaa gggtaccatg ttactaccgg tgaacctgtt tgccagcccc
    20881 gtcgtccaaa tagtcggata gataaagtac gatatatgtt caataaaata acttagtgta
    20941 ttttatgttg ttatataaat atggtttctt gttaaat
//
LOCUS       DAVLTG010000153         2651 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00040813
            SAMN33607253-rid17937553.guided.105, whole genome shotgun sequence.
ACCESSION   DAVLTG010000153 DAVLTG010000000
VERSION     DAVLTG010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607253
            Sequence Read Archive: SRR23725650
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721527.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721527.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:21:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,154
            CDSs (total)                      :: 2,108
            Genes (coding)                    :: 1,979
            CDSs (with protein)               :: 1,979
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 129
            CDSs (without protein)            :: 129
            Pseudo Genes (ambiguous residues) :: 0 of 129
            Pseudo Genes (frameshifted)       :: 59 of 129
            Pseudo Genes (incomplete)         :: 63 of 129
            Pseudo Genes (internal stop)      :: 38 of 129
            Pseudo Genes (multiple problems)  :: 25 of 129
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607253-rid17937553.guided.105"
                     /strain="AUSMDU00040813"
                     /serotype="19A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST2013"
     gene            83..166
                     /locus_tag="VYN12_002151"
     CDS             83..166
                     /locus_tag="VYN12_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1416440.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            291..1028
                     /gene="erm(B)"
                     /locus_tag="VYN12_002152"
     CDS             291..1028
                     /gene="erm(B)"
                     /locus_tag="VYN12_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1416441.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            1383..1937
                     /locus_tag="VYN12_002153"
     CDS             1383..1937
                     /locus_tag="VYN12_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1416442.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            1941..>2651
                     /locus_tag="VYN12_002154"
     CDS             1941..>2651
                     /locus_tag="VYN12_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /protein_id="HEV1416443.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASM"
BASE COUNT          954 a          415 c          442 g          840 t
ORIGIN      
        1 gcattatctt aaaattttgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
       61 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
      121 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
      181 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
      241 gtttaacttc tgtatttgtt tatagatgta atcacttcag gagagattac atgaacaaaa
      301 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
      361 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
      421 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
      481 tcaacttatc gtcagaaaaa ttaaaactga atactcgtgt cactttaatt caccaagata
      541 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggaat attccttacc
      601 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccgtgcgtct gacatctatc
      661 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
      721 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
      781 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
      841 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
      901 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
      961 gtaccattac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     1021 ggaaataatt ctatgagtcg cttttgtaaa tttggaaagt tacacgttac taaagggaat
     1081 gtagataaat tattaggtat actactgaca gcttccaagg agctaaagag gtccctagcg
     1141 cctacgggga atttgtatcg ataaggaata gatttaaaaa tttcgctgtt attttgtaca
     1201 ataaggataa atttgaatgg taccataaac gaccgtttat ggtacctttt cattttcctg
     1261 ctttttctaa atgtttttta agtaaatcaa gtaccaaaat ccgttccttt ttcatagttc
     1321 ctatatagtt atacttaatg agttatggta catttaaatt ataaaattaa ggaggttttt
     1381 ttatgatttt tggctatgct cgagtgagta cggatgatca aaatcttagt ttacaaattg
     1441 atgcacttac tcattatgga attgataaat tatttcaaga aaaagtaact ggtgcgaaaa
     1501 aagaccgacc gcaattagaa gaaatgatca acctactacg tgaaggagat tctgttgtca
     1561 tttacaagtt agatcgaatt tcacgatcaa ctaaacattt gattgaactt tctgaattat
     1621 ttgaagaact tagtgtcaat tttatatcta ttcaagataa cgtagatact tcaacgtcta
     1681 tgggaagatt ctttttccga gttatggcta gtttagcaga actggaacgg gatattatta
     1741 ttgaacgaac taactctggt cttaaggcag ccagagtccg aggaaaaaaa gggggccgtc
     1801 caagtaaagg taagctatca attgatttag ctttaaaaat gtatgacagc aaagagtatt
     1861 ctattcgtca aattcttgat gcctctaaat taagcaaaac aaccttttac cgttacctca
     1921 ataaaaggaa tgcttaagat atggctatga aaagaatttt aactacttca cagcgtgaac
     1981 aacttctttc tgtagaccac ttatcagaag aggattttaa agcgtatttt agtttttctg
     2041 attatgatct ggaggttatt aatcaacacc gtggaaaggt caataaacta ggatttgcga
     2101 tacaactttg tttggcccgg tatcctgggt gttctttaag taattggccg attaaatcaa
     2161 ccagactaac ttcttatgtg agtcgacagc tccatcttga tgcaattgat ttaaattcat
     2221 atgatcatag aaatacacgt gcaaatcact tcaacgagat cttagaagta ttcaactatc
     2281 atcgattcgg tagtgctaat acacaaaaac agttaataga atatttaatt gaactagctt
     2341 tagaaaatga tgactctatc tatctaatga aaaaaacaat tgatttctta actcgaaaaa
     2401 gaattatttt tccatctata gctacacttg aagacattat aagccgctgt cgagataaag
     2461 cagaaaacaa cttattttca atattactct gttcattaac agatatacaa attgaaaaac
     2521 tagagagttt gtttcaaatt tatgaagaga cgaaaataac taaactcgct tggctaaaag
     2581 acattccagg taaggcaaat ccagaaagct ttatgagtat ttgtaaaaaa gtggaagtga
     2641 ttgcttccat g
//
